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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3r7uX96Cyclin-dependent kinase 22.7.11.22

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
3r7uX96Cyclin-dependent kinase 22.7.11.221.000
3r7iX9ICyclin-dependent kinase 22.7.11.220.675
3rm618ZCyclin-dependent kinase 22.7.11.220.620
4ek610KCyclin-dependent kinase 22.7.11.220.609
3r7yZ04Cyclin-dependent kinase 22.7.11.220.596
4nj32KDCyclin-dependent kinase 22.7.11.220.576
3r1yX76Cyclin-dependent kinase 22.7.11.220.573
3sqq99ZCyclin-dependent kinase 22.7.11.220.570
4fki09KCyclin-dependent kinase 22.7.11.220.569
2a0cCK9Cyclin-dependent kinase 22.7.11.220.568
1pxoCK7Cyclin-dependent kinase 22.7.11.220.567
3ezrEZRCyclin-dependent kinase 22.7.11.220.561
3rpo24ZCyclin-dependent kinase 22.7.11.220.561
2c6o4SPCyclin-dependent kinase 22.7.11.220.553
3r7vZ02Cyclin-dependent kinase 22.7.11.220.552
3le62BZCyclin-dependent kinase 22.7.11.220.550
3lfqA28Cyclin-dependent kinase 22.7.11.220.548
2vtpLZ9Cyclin-dependent kinase 22.7.11.220.547
4fkq42KCyclin-dependent kinase 22.7.11.220.545
3qwjX6ACyclin-dependent kinase 22.7.11.220.544
4fkt48KCyclin-dependent kinase 22.7.11.220.542
3s2pPMUCyclin-dependent kinase 22.7.11.220.540
2r3lSCWCyclin-dependent kinase 22.7.11.220.538
3r1sX73Cyclin-dependent kinase 22.7.11.220.538
1w8cN69Cyclin-dependent kinase 22.7.11.220.535
2vtjLZ4Cyclin-dependent kinase 22.7.11.220.535
3r83Z14Cyclin-dependent kinase 22.7.11.220.535
2vthLZ2Cyclin-dependent kinase 22.7.11.220.534
4fklCK2Cyclin-dependent kinase 22.7.11.220.534
3fz1B98Cyclin-dependent kinase 22.7.11.220.533
2a4lRRCCyclin-dependent kinase 22.7.11.220.532
3qqfX07Cyclin-dependent kinase 22.7.11.220.532
3rm719ZCyclin-dependent kinase 22.7.11.220.532
3s1h56ZCyclin-dependent kinase 22.7.11.220.531
2r3p3SCCyclin-dependent kinase 22.7.11.220.529
3lfnA27Cyclin-dependent kinase 22.7.11.220.528
4fkpLS5Cyclin-dependent kinase 22.7.11.220.528
1ykr628Cyclin-dependent kinase 22.7.11.220.527
2b53D23Cyclin-dependent kinase 22.7.11.220.527
2r3mSCXCyclin-dependent kinase 22.7.11.220.527
2w06FRVCyclin-dependent kinase 22.7.11.220.527
3qxoX65Cyclin-dependent kinase 22.7.11.220.527
3qzhX69Cyclin-dependent kinase 22.7.11.220.527
1oitHDTCyclin-dependent kinase 22.7.11.220.526
3lfsA07Cyclin-dependent kinase 22.7.11.220.526
3rak03ZCyclin-dependent kinase 22.7.11.220.526
2c6lDT4Cyclin-dependent kinase 22.7.11.220.524
3qruX19Cyclin-dependent kinase 22.7.11.220.524
2vtoLZ8Cyclin-dependent kinase 22.7.11.220.521
3r71X86Cyclin-dependent kinase 22.7.11.220.521
1w0xOLOCyclin-dependent kinase 22.7.11.220.520
3r8lZ30Cyclin-dependent kinase 22.7.11.220.518
3pxyJWSCyclin-dependent kinase 22.7.11.220.517
2b52D42Cyclin-dependent kinase 22.7.11.220.516
3qqlX03Cyclin-dependent kinase 22.7.11.220.516
3ezvEZVCyclin-dependent kinase 22.7.11.220.513
3qx2X63Cyclin-dependent kinase 22.7.11.220.513
4fkj11KCyclin-dependent kinase 22.7.11.220.513
2btrU73Cyclin-dependent kinase 22.7.11.220.512
2uzoC62Cyclin-dependent kinase 22.7.11.220.511
3rahO1ZCyclin-dependent kinase 22.7.11.220.511
2exmZIPCyclin-dependent kinase 22.7.11.220.508
2r64740Cyclin-dependent kinase 22.7.11.220.507
3qrtX14Cyclin-dependent kinase 22.7.11.220.507
1p2a5BNCyclin-dependent kinase 22.7.11.220.505
2r3iSCFCyclin-dependent kinase 22.7.11.220.505
3r8vZ62Cyclin-dependent kinase 22.7.11.220.504
1b39ATPCyclin-dependent kinase 22.7.11.220.503
2c6kDT2Cyclin-dependent kinase 22.7.11.220.503
2r3jSCJCyclin-dependent kinase 22.7.11.220.503
3r73X87Cyclin-dependent kinase 22.7.11.220.503
4ek816KCyclin-dependent kinase 22.7.11.220.503
3rni21ZCyclin-dependent kinase 22.7.11.220.501
4fkr45KCyclin-dependent kinase 22.7.11.220.501
3sw418KCyclin-dependent kinase 22.7.11.220.500
1ke5LS1Cyclin-dependent kinase 22.7.11.220.499
1pxmCK5Cyclin-dependent kinase 22.7.11.220.499
1y8yCT7Cyclin-dependent kinase 22.7.11.220.499
3ral04ZCyclin-dependent kinase 22.7.11.220.497
2r3kSCQCyclin-dependent kinase 22.7.11.220.495
2vtiLZ3Cyclin-dependent kinase 22.7.11.220.495
2xmyCDKCyclin-dependent kinase 22.7.11.220.493
1vyzN5BCyclin-dependent kinase 22.7.11.220.492
2btsU32Cyclin-dependent kinase 22.7.11.220.492
1ke7LS3Cyclin-dependent kinase 22.7.11.220.491
3qtxX43Cyclin-dependent kinase 22.7.11.220.490
3qqkX02Cyclin-dependent kinase 22.7.11.220.487
1v1k3FPCyclin-dependent kinase 22.7.11.220.485
3qtzX42Cyclin-dependent kinase 22.7.11.220.485
3rpy27ZCyclin-dependent kinase 22.7.11.220.485
3rjc06ZCyclin-dependent kinase 22.7.11.220.484
1gih1PUCyclin-dependent kinase 22.7.11.220.483
3rkb12ZCyclin-dependent kinase 22.7.11.220.483
3rpv26ZCyclin-dependent kinase 22.7.11.220.483
1g5sI17Cyclin-dependent kinase 22.7.11.220.482
3rk708ZCyclin-dependent kinase 22.7.11.220.482
4fkg4CKCyclin-dependent kinase 22.7.11.220.481
3qqhX0ACyclin-dependent kinase 22.7.11.220.480
3rk909ZCyclin-dependent kinase 22.7.11.220.480
4fko20KCyclin-dependent kinase 22.7.11.220.480
1vyw292Cyclin-dependent kinase 22.7.11.220.479
1ckpPVBCyclin-dependent kinase 22.7.11.220.478
1ke6LS2Cyclin-dependent kinase 22.7.11.220.475
2r3fSC8Cyclin-dependent kinase 22.7.11.220.475
2vtnLZ7Cyclin-dependent kinase 22.7.11.220.475
3qtuX44Cyclin-dependent kinase 22.7.11.220.475
5aniES4Cyclin-dependent kinase 22.7.11.220.475
1di8DTQCyclin-dependent kinase 22.7.11.220.474
2c5yMTWCyclin-dependent kinase 22.7.11.220.474
3rmf20ZCyclin-dependent kinase 22.7.11.220.474
2w1hL0FCyclin-dependent kinase 22.7.11.220.472
3qzgX67Cyclin-dependent kinase 22.7.11.220.472
4acm7YGCyclin-dependent kinase 22.7.11.220.472
3r28XA0Cyclin-dependent kinase 22.7.11.220.471
3r7eX88Cyclin-dependent kinase 22.7.11.220.471
3sw719KCyclin-dependent kinase 22.7.11.220.471
1h0w207Cyclin-dependent kinase 22.7.11.220.470
1gz8MBPCyclin-dependent kinase 22.7.11.220.469
1hckATPCyclin-dependent kinase 22.7.11.220.469
1pxpCK8Cyclin-dependent kinase 22.7.11.220.469
2vtqLZACyclin-dependent kinase 22.7.11.220.469
2r3r6SCCyclin-dependent kinase 22.7.11.220.468
3iggEFQCyclin-dependent kinase 22.7.11.220.468
3qziX72Cyclin-dependent kinase 22.7.11.220.468
3raiX85Cyclin-dependent kinase 22.7.11.220.468
1ke9LS5Cyclin-dependent kinase 22.7.11.220.467
3r1qX75Cyclin-dependent kinase 22.7.11.220.467
3r6xX84Cyclin-dependent kinase 22.7.11.220.467
2c6iDT1Cyclin-dependent kinase 22.7.11.220.466
3qx4X4BCyclin-dependent kinase 22.7.11.220.466
3qxpX64Cyclin-dependent kinase 22.7.11.220.466
4bgh3I6Cyclin-dependent kinase 22.7.11.220.466
1h1r6CPCyclin-dependent kinase 22.7.11.220.465
2bheBRYCyclin-dependent kinase 22.7.11.220.464
2duv371Cyclin-dependent kinase 22.7.11.220.464
2fvdLIACyclin-dependent kinase 22.7.11.220.464
2i40BLZCyclin-dependent kinase 22.7.11.220.464
2uznC96Cyclin-dependent kinase 22.7.11.220.464
2vtsLZCCyclin-dependent kinase 22.7.11.220.464
1oirHDYCyclin-dependent kinase 22.7.11.220.463
2r3gSC9Cyclin-dependent kinase 22.7.11.220.463
4fks46KCyclin-dependent kinase 22.7.11.220.463
2vttLZDCyclin-dependent kinase 22.7.11.220.462
4erwSTUCyclin-dependent kinase 22.7.11.220.462
2b55D31Cyclin-dependent kinase 22.7.11.220.460
3qtrX36Cyclin-dependent kinase 22.7.11.220.460
3qwkX62Cyclin-dependent kinase 22.7.11.220.459
1gii1PUCyclin-dependent kinase 22.7.11.220.458
1oguST8Cyclin-dependent kinase 22.7.11.220.457
1pxlCK4Cyclin-dependent kinase 22.7.11.220.457
3r9hZ67Cyclin-dependent kinase 22.7.11.220.457
3roy22ZCyclin-dependent kinase 22.7.11.220.457
3wblPDYCyclin-dependent kinase 22.7.11.220.457
4kd11QKCyclin-dependent kinase 22.7.11.220.457
3ti1B49Cyclin-dependent kinase 22.7.11.220.456
1aq1STUCyclin-dependent kinase 22.7.11.220.455
2r3o2SCCyclin-dependent kinase 22.7.11.220.454
2vtrLZBCyclin-dependent kinase 22.7.11.220.454
3qu0X40Cyclin-dependent kinase 22.7.11.220.452
3bhtMFRCyclin-dependent kinase 22.7.11.220.451
4fkv61KCyclin-dependent kinase 22.7.11.220.451
4lyn1YGCyclin-dependent kinase 22.7.11.220.451
1pyePM1Cyclin-dependent kinase 22.7.11.220.450
2uzeC95Cyclin-dependent kinase 22.7.11.220.450
3pj8404Cyclin-dependent kinase 22.7.11.220.450
3ddqRRCCyclin-dependent kinase 22.7.11.220.449
3r8pZ46Cyclin-dependent kinase 22.7.11.220.449
2c69CT8Cyclin-dependent kinase 22.7.11.220.448
2r3q5SCCyclin-dependent kinase 22.7.11.220.448
2wpa889Cyclin-dependent kinase 22.7.11.220.448
2bhhRYUCyclin-dependent kinase 22.7.11.220.447
3r9dX6BCyclin-dependent kinase 22.7.11.220.447
4ks8B49Serine/threonine-protein kinase PAK 62.7.11.10.447
2vu3LZECyclin-dependent kinase 22.7.11.220.446
3ig7EFPCyclin-dependent kinase 22.7.11.220.446
4bcpT3CCyclin-dependent kinase 22.7.11.220.446
1finATPCyclin-dependent kinase 22.7.11.220.445
4fx360KCyclin-dependent kinase 22.7.11.220.445
1fvv107Cyclin-dependent kinase 22.7.11.220.444
2w17I19Cyclin-dependent kinase 22.7.11.220.444
3tnwF18Cyclin-dependent kinase 22.7.11.220.444
4fkw62KCyclin-dependent kinase 22.7.11.220.444
1urwI1PCyclin-dependent kinase 22.7.11.220.443
2vtlLZ5Cyclin-dependent kinase 22.7.11.220.443
4ez30S0Cyclin-dependent kinase 22.7.11.220.442
1y91CT9Cyclin-dependent kinase 22.7.11.220.441
4nk92K5Fibroblast growth factor receptor 1/0.441
3nynSGVG protein-coupled receptor kinase 62.7.11.160.440
3r9nZ68Cyclin-dependent kinase 22.7.11.220.440