sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1t48 | BB3 | Tyrosine-protein phosphatase non-receptor type 1 | 3.1.3.48 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 1t48 | BB3 | Tyrosine-protein phosphatase non-receptor type 1 | 3.1.3.48 | 1.000 | |
| 4nbl | 2J6 | Caspase-6 | 3.4.22.59 | 0.485 | |
| 1ozq | PRF | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.484 | |
| 2jc6 | QPP | Calcium/calmodulin-dependent protein kinase type 1D | 2.7.11.17 | 0.482 | |
| 2vt4 | P32 | Beta-1 adrenergic receptor | / | 0.477 | |
| 4fa3 | 0SL | Aldo-keto reductase family 1 member C3 | / | 0.475 | |
| 4kbn | 25U | Dihydrofolate reductase | 1.5.1.3 | 0.475 | |
| 3hv3 | R49 | Mitogen-activated protein kinase 14 | / | 0.474 | |
| 4nbi | D3Y | D-tyrosyl-tRNA(Tyr) deacylase | / | 0.474 | |
| 1zkl | IBM | High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A | 3.1.4.53 | 0.473 | |
| 3bbf | GDP | Nucleoside diphosphate kinase B | 2.7.4.6 | 0.473 | |
| 3lfe | Z84 | Mitogen-activated protein kinase 14 | / | 0.473 | |
| 4llk | MEW | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.473 | |
| 1zkn | IBM | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.472 | |
| 2bjs | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.472 | |
| 4hqv | QEI | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.470 | |
| 4a4o | 664 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.469 | |
| 1cl2 | PPG | Cystathionine beta-lyase MetC | 4.4.1.8 | 0.468 | |
| 2fjm | 073 | Tyrosine-protein phosphatase non-receptor type 1 | 3.1.3.48 | 0.468 | |
| 4b4v | L34 | Bifunctional protein FolD | / | 0.467 | |
| 1f3e | DPZ | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.466 | |
| 1ygj | RMC | Pyridoxal kinase | 2.7.1.35 | 0.466 | |
| 2zhf | 49U | Prothrombin | 3.4.21.5 | 0.466 | |
| 3p9t | TCL | Repressor | / | 0.466 | |
| 3sl6 | JN8 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.466 | |
| 4hsh | QEI | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.466 | |
| 1y5x | E89 | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.465 | |
| 2fmn | 4HF | 5,10-methylenetetrahydrofolate reductase | 1.5.1.20 | 0.465 | |
| 2gsq | GBI | Glutathione S-transferase | 2.5.1.18 | 0.465 | |
| 3arv | SAU | Chitinase A | / | 0.465 | |
| 4iaq | 2GM | 5-hydroxytryptamine receptor 1B | / | 0.465 | |
| 1fdw | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.464 | |
| 1y6q | TDI | 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase | 3.2.2.9 | 0.464 | |
| 1uho | VDN | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.463 | |
| 2yat | EEU | Estrogen receptor | / | 0.463 | |
| 3nu0 | 3TU | Dihydrofolate reductase | 1.5.1.3 | 0.463 | |
| 2fzj | DH3 | Dihydrofolate reductase | 1.5.1.3 | 0.462 | |
| 2y60 | M8F | Isopenicillin N synthase | 1.21.3.1 | 0.462 | |
| 4b4w | 9L9 | Bifunctional protein FolD | / | 0.462 | |
| 4j53 | 1J4 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.462 | |
| 4pnm | NU1 | Tankyrase-2 | 2.4.2.30 | 0.462 | |
| 1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.461 | |
| 1qti | GNT | Acetylcholinesterase | 3.1.1.7 | 0.460 | |
| 2bu9 | HFV | Isopenicillin N synthase | 1.21.3.1 | 0.460 | |
| 2xvw | 9NR | Serum albumin | / | 0.460 | |
| 1dgh | NDP | Catalase | 1.11.1.6 | 0.459 | |
| 2tpl | HPP | Tyrosine phenol-lyase | 4.1.99.2 | 0.459 | |
| 4a6d | SAM | Acetylserotonin O-methyltransferase | 2.1.1.4 | 0.459 | |
| 2ycz | I32 | Beta-1 adrenergic receptor | / | 0.459 | |
| 1blz | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.458 | |
| 3u3o | 3QV | Sulfotransferase 1A1 | 2.8.2.1 | 0.458 | |
| 4a4l | 939 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.458 | |
| 4do3 | 0LA | Fatty-acid amide hydrolase 1 | 3.5.1.99 | 0.458 | |
| 4iar | ERM | 5-hydroxytryptamine receptor 1B | / | 0.458 | |
| 2hxz | H7J | Cathepsin S | 3.4.22.27 | 0.457 | |
| 2rd2 | QSI | Glutamine--tRNA ligase | 6.1.1.18 | 0.457 | |
| 2x20 | PID | Peridinin-chlorophyll a-binding protein 1, chloroplastic | / | 0.457 | |
| 3b8x | G4M | Putative pyridoxamine 5-phosphate-dependent dehydrase | / | 0.457 | |
| 3gie | ACP | Sensor histidine kinase DesK | 2.7.13.3 | 0.457 | |
| 3nwl | NDP | Catalase | 1.11.1.6 | 0.457 | |
| 3qly | 55V | Uncharacterized protein | / | 0.457 | |
| 4dz5 | NAP | Aldo-keto reductase family 1 member C3 | / | 0.457 | |
| 4mrx | CZH | Obelin | / | 0.457 | |
| 1e62 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.456 | |
| 1jxz | BCA | 4-chlorobenzoyl coenzyme A dehalogenase | 3.8.1.7 | 0.456 | |
| 1oyn | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.456 | |
| 2i16 | LDT | Aldose reductase | 1.1.1.21 | 0.456 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.456 | |
| 4qij | 1HA | 1,4-dihydroxy-2-naphthoyl-CoA synthase | / | 0.456 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.455 | |
| 1j3j | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.455 | |
| 1kmv | LII | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 3h4v | DVP | Pteridine reductase 1 | 1.5.1.33 | 0.455 | |
| 4b11 | 7I1 | Glycylpeptide N-tetradecanoyltransferase | / | 0.455 | |
| 1xor | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.454 | |
| 2o8h | 227 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.454 | |
| 2re8 | GSU | Glutamine--tRNA ligase | 6.1.1.18 | 0.454 | |
| 2xtb | KRM | Adenosine kinase, putative | / | 0.454 | |
| 3gcq | 1BU | Mitogen-activated protein kinase 14 | / | 0.454 | |
| 4lm4 | JPZ | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.454 | |
| 5kf2 | COA | Predicted acetyltransferase | / | 0.454 | |
| 2bf7 | HBI | Pteridine reductase 1 | 1.5.1.33 | 0.453 | |
| 2poq | ISD | Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase | 1.3.1.20 | 0.453 | |
| 2xk4 | OL2 | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.453 | |
| 3g4i | D71 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.453 | |
| 4fk3 | 325 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.453 | |
| 4kp6 | 1S1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.453 | |
| 4zas | TYD | CalS13 | / | 0.453 | |
| 1e2l | TMC | Thymidine kinase | / | 0.452 | |
| 1w19 | T4P | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.452 | |
| 3djf | BC3 | Purine nucleoside phosphorylase | / | 0.452 | |
| 4ddr | MMV | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 4h7z | GUN | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.452 | |
| 1gj5 | 130 | Prothrombin | 3.4.21.5 | 0.451 | |
| 1h42 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.451 | |
| 1v3q | 2DI | Purine nucleoside phosphorylase | 2.4.2.1 | 0.451 | |
| 2ilt | NN1 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.451 | |
| 3arp | DEQ | Chitinase A | / | 0.451 | |
| 3qpn | PFK | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.451 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.451 | |
| 4xzj | NAD | Putative NAD(+)--arginine ADP-ribosyltransferase Vis | 2.4.2.31 | 0.451 | |
| 1piw | NAP | NADP-dependent alcohol dehydrogenase 6 | 1.1.1.2 | 0.450 | |
| 1vot | HUP | Acetylcholinesterase | 3.1.1.7 | 0.450 | |
| 2qhx | FE1 | Pteridine reductase 1 | 1.5.1.33 | 0.450 | |
| 2qxw | LDT | Aldose reductase | 1.1.1.21 | 0.450 | |
| 2wjo | QUD | Beta-secretase 1 | 3.4.23.46 | 0.450 | |
| 3nxy | D2H | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 3prf | FP3 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.450 | |
| 4f1t | H52 | Probable serine/threonine-protein kinase roco4 | 2.7.11.1 | 0.450 | |
| 4wo5 | 324 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.450 | |
| 1d3d | BZT | Prothrombin | 3.4.21.5 | 0.449 | |
| 1s3y | TQT | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 3s41 | S41 | Glucokinase | 2.7.1.2 | 0.449 | |
| 3tvx | PNX | cAMP-specific 3',5'-cyclic phosphodiesterase 4A | 3.1.4.53 | 0.449 | |
| 3zpq | XF5 | Beta-1 adrenergic receptor | / | 0.449 | |
| 4at4 | T6E | BDNF/NT-3 growth factors receptor | 2.7.10.1 | 0.449 | |
| 4c71 | 7RD | 3-oxoacyl-ACP synthase | / | 0.449 | |
| 4n3l | 2FN | Prothrombin | 3.4.21.5 | 0.449 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.448 | |
| 1pd8 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 1qv0 | CZH | Obelin | / | 0.448 | |
| 1s3u | TQD | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.448 | |
| 2xk7 | 30E | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.448 | |
| 3exf | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.448 | |
| 3exf | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.448 | |
| 3ey4 | 352 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.448 | |
| 3nrr | D16 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.448 | |
| 3qwc | 98P | Prothrombin | 3.4.21.5 | 0.448 | |
| 3szf | DCQ | Sulfide-quinone reductase | / | 0.448 | |
| 3x0c | 5GP | Phosphatidylinositol 5-phosphate 4-kinase type-2 beta | 2.7.1.149 | 0.448 | |
| 4c6z | TLE | 3-oxoacyl-ACP synthase | / | 0.448 | |
| 4dhy | S41 | Glucokinase | 2.7.1.2 | 0.448 | |
| 4hf4 | 15H | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.448 | |
| 4kd7 | 9DR | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 5ab7 | MLC | Nonspecific lipid-transfer protein, putative | / | 0.448 | |
| 5h8t | RTL | Retinol-binding protein 1 | / | 0.448 | |
| 1zq5 | E04 | Aldo-keto reductase family 1 member C3 | / | 0.447 | |
| 2fm5 | M99 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.447 | |
| 3akl | ADP | Serine/threonine-protein kinase CtkA | 2.7.11.1 | 0.447 | |
| 3k3h | BYE | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.447 | |
| 4ea0 | 651 | Dehydrosqualene synthase | / | 0.447 | |
| 1be4 | PCG | Nucleoside diphosphate kinase A 2 | 2.7.4.6 | 0.446 | |
| 1oyt | FSN | Prothrombin | 3.4.21.5 | 0.446 | |
| 2a9z | 26A | Adenosine kinase | 2.7.1.20 | 0.446 | |
| 2bnp | MST | Reaction center protein L chain | / | 0.446 | |
| 2f98 | NGV | Aklanonic acid methyl ester cyclase AcmA | 5.5.1.23 | 0.446 | |
| 2uuk | 897 | Prothrombin | 3.4.21.5 | 0.446 | |
| 3o9l | LPN | Renin | 3.4.23.15 | 0.446 | |
| 3ppk | FNI | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.446 | |
| 4fhd | 0TT | Spore photoproduct lyase | / | 0.446 | |
| 1dr4 | HBI | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 1nbm | ADP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.445 | |
| 1ohk | COP | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 2qx7 | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.445 | |
| 3k45 | 51P | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 3qiy | QI1 | Botulinum neurotoxin type A | 3.4.24.69 | 0.445 | |
| 4b1i | A8P | Poly(ADP-ribose) glycohydrolase | 3.2.1.143 | 0.445 | |
| 4ckr | DI1 | Epithelial discoidin domain-containing receptor 1 | 2.7.10.1 | 0.445 | |
| 4ky4 | 04J | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.445 | |
| 4mry | CEI | Obelin | / | 0.445 | |
| 4muw | 2F4 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.445 | |
| 4u0o | MTA | Lipoyl synthase 2 | / | 0.445 | |
| 1fds | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.444 | |
| 1k4h | APQ | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.444 | |
| 1lnm | DTX | Bilin-binding protein | / | 0.444 | |
| 1q9m | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.444 | |
| 1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
| 1yry | MSG | Purine nucleoside phosphorylase | 2.4.2.1 | 0.444 | |
| 2io6 | 330 | Wee1-like protein kinase | 2.7.10.2 | 0.444 | |
| 2w6c | BM4 | Acetylcholinesterase | 3.1.1.7 | 0.444 | |
| 2y6f | M9F | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
| 3d3p | 20A | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.444 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.444 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.444 | |
| 3ghh | 2NF | CD38 molecule | / | 0.444 | |
| 3mau | PLR | Putative sphingosine-1-phosphate lyase | / | 0.444 | |
| 3tfu | PL8 | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase | 2.6.1.62 | 0.444 | |
| 4jxx | ATP | Glutamine--tRNA ligase | 6.1.1.18 | 0.444 | |
| 4nbj | D3Y | D-tyrosyl-tRNA(Tyr) deacylase | / | 0.444 | |
| 4oex | 5EO | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.444 | |
| 4phl | PIL | Phosphodiesterase | / | 0.444 | |
| 4x24 | TDI | 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase | / | 0.444 | |
| 4yfy | 1YJ | VioF | / | 0.444 | |
| 4z87 | GDP | Inosine-5'-monophosphate dehydrogenase | / | 0.444 | |
| 1jf2 | CZH | Obelin | / | 0.443 | |
| 1sjw | NGV | Nogalonic acid methyl ester cyclase | / | 0.443 | |
| 2jh0 | 701 | Prothrombin | 3.4.21.5 | 0.443 | |
| 2jj2 | ADP | ATP synthase subunit alpha, mitochondrial | / | 0.443 | |
| 2jj2 | ADP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.443 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.443 | |
| 2xnm | WGZ | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.443 | |
| 2yy2 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.443 | |
| 3cqe | P91 | Wee1-like protein kinase | 2.7.10.2 | 0.443 | |
| 3gyf | 51P | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 3iej | 599 | Cathepsin S | 3.4.22.27 | 0.443 | |
| 3ptz | UDX | UDP-glucose 6-dehydrogenase | 1.1.1.22 | 0.443 | |
| 3vf6 | 0H6 | Glucokinase | 2.7.1.2 | 0.443 | |
| 4a95 | 9MT | Glycylpeptide N-tetradecanoyltransferase | / | 0.443 | |
| 4k6i | 9RA | Retinoic acid receptor RXR-alpha | / | 0.443 | |
| 4nbn | 2J7 | Caspase-6 | 3.4.22.59 | 0.443 | |
| 3eml | ZMA | Adenosine receptor A2a | / | 0.443 | |
| 1dlr | MXA | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1fdu | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.442 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
| 1w2c | ANP | Inositol-trisphosphate 3-kinase A | 2.7.1.127 | 0.442 | |
| 1xoq | ROF | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.442 | |
| 2b04 | CHO | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.442 | |
| 2q6h | CXX | Na(+):neurotransmitter symporter (Snf family) | / | 0.442 | |
| 3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.442 | |
| 3eon | 341 | Glutaryl-CoA dehydrogenase | / | 0.442 | |
| 3jq6 | DX1 | Pteridine reductase, putative | / | 0.442 | |
| 3lm4 | HPX | Catechol 2,3-dioxygenase | / | 0.442 | |
| 3njo | PYV | Abscisic acid receptor PYR1 | / | 0.442 | |
| 3nxr | D2D | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 4bjb | P34 | Tankyrase-2 | 2.4.2.30 | 0.442 | |
| 4dpd | DHF | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.442 | |
| 4feu | 537 | Aminoglycoside 3'-phosphotransferase AphA1-IAB | / | 0.442 | |
| 4k9y | K9Y | Focal adhesion kinase 1 | 2.7.10.2 | 0.442 | |
| 4nhy | PD2 | Prolyl 3-hydroxylase OGFOD1 | 1.14.11 | 0.442 | |
| 4tta | FMC | Purine nucleoside phosphorylase DeoD-type | / | 0.442 | |
| 1dgf | NDP | Catalase | 1.11.1.6 | 0.441 | |
| 1efz | PRF | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.441 | |
| 1pd9 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 1pwm | FID | Aldose reductase | 1.1.1.21 | 0.441 | |
| 2ovy | PFJ | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.441 | |
| 2vz0 | D64 | Pteridine reductase | / | 0.441 | |
| 3d73 | NBB | Pheromone-binding protein ASP1 | / | 0.441 | |
| 4bfu | ZVU | Pantothenate kinase | 2.7.1.33 | 0.441 | |
| 4ddl | 0JQ | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.441 | |
| 4gh6 | LUO | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.441 | |
| 4oew | 5IO | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.441 | |
| 4y6n | UPG | Glucosyl-3-phosphoglycerate synthase | 2.4.1.266 | 0.441 | |
| 5d7p | AR6 | NAD-dependent protein deacetylase sirtuin-2 | 3.5.1 | 0.441 | |
| 5epv | ACP | Blue-light-activated histidine kinase | 2.7.13.3 | 0.441 | |
| 5std | UNN | Scytalone dehydratase | 4.2.1.94 | 0.441 | |
| 1fcy | 564 | Retinoic acid receptor gamma | / | 0.440 | |
| 1kyy | INI | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.440 | |
| 1odn | APV | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
| 1ry0 | PG2 | Aldo-keto reductase family 1 member C3 | / | 0.440 | |
| 1udt | VIA | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.440 | |
| 2bxq | IMN | Serum albumin | / | 0.440 | |
| 2iqd | LPA | Aldose reductase | 1.1.1.21 | 0.440 | |
| 2rl5 | 2RL | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.440 | |
| 2vqj | TFG | Histone deacetylase 4 | 3.5.1.98 | 0.440 | |
| 2wo7 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
| 2xk8 | 5R1 | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.440 | |
| 3qpp | PFW | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.440 | |
| 3ug8 | IMN | Aldo-keto reductase family 1 member C3 | / | 0.440 | |
| 3w5e | NVW | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.440 | |
| 4fsa | 0V3 | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.440 |