sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1l4m | NCN | Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase | 2.4.2.21 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 1l4m | NCN | Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase | 2.4.2.21 | 1.000 | |
| 1l4k | NCN | Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase | 2.4.2.21 | 0.758 | |
| 1l4f | NCN | Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase | 2.4.2.21 | 0.712 | |
| 1l4h | NCN | Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase | 2.4.2.21 | 0.694 | |
| 1l4l | NCN | Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase | 2.4.2.21 | 0.690 | |
| 1jha | AAM | Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase | 2.4.2.21 | 0.675 | |
| 1d0v | RBZ | Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase | 2.4.2.21 | 0.669 | |
| 1jho | RMB | Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase | 2.4.2.21 | 0.639 | |
| 1l5o | NCN | Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase | 2.4.2.21 | 0.613 | |
| 1l4g | NCN | Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase | 2.4.2.21 | 0.612 | |
| 1jhr | P2P | Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase | 2.4.2.21 | 0.607 | |
| 1l4e | RBZ | Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase | 2.4.2.21 | 0.606 | |
| 1l5k | 1RB | Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase | 2.4.2.21 | 0.604 | |
| 1l5l | 7RP | Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase | 2.4.2.21 | 0.536 | |
| 2qo9 | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.491 | |
| 4g2f | C07 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.484 | |
| 2q61 | SF1 | Peroxisome proliferator-activated receptor gamma | / | 0.479 | |
| 1pdh | FAS | p-hydroxybenzoate hydroxylase | / | 0.478 | |
| 1jhq | PMO | Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase | 2.4.2.21 | 0.477 | |
| 1l5m | 7RA | Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase | 2.4.2.21 | 0.475 | |
| 2giv | ACO | Histone acetyltransferase KAT8 | / | 0.473 | |
| 3mdm | FJZ | Cholesterol 24-hydroxylase | / | 0.472 | |
| 4xld | BRL | Peroxisome proliferator-activated receptor gamma | / | 0.472 | |
| 2ejj | SAH | Diphthine synthase | / | 0.469 | |
| 2q9f | C3S | Cholesterol 24-hydroxylase | / | 0.469 | |
| 4gk3 | L87 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.469 | |
| 1dbv | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.468 | |
| 1mg5 | NAI | Alcohol dehydrogenase | 1.1.1.1 | 0.466 | |
| 1dz4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.465 | |
| 4nd2 | A3D | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.465 | |
| 4z0h | NAD | Glyceraldehyde-3-phosphate dehydrogenase GAPC1, cytosolic | 1.2.1.12 | 0.465 | |
| 5c7o | NAD | Glyceraldehyde-3-phosphate dehydrogenase, testis-specific | 1.2.1.12 | 0.465 | |
| 1cjk | FOK | Adenylate cyclase type 2 | / | 0.464 | |
| 1cjk | FOK | Adenylate cyclase type 5 | / | 0.464 | |
| 1u8f | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.464 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.464 | |
| 2egl | SAH | Diphthine synthase | / | 0.463 | |
| 2nu9 | COA | Succinate--CoA ligase [ADP-forming] subunit alpha | 6.2.1.5 | 0.463 | |
| 3mvq | NDP | Glutamate dehydrogenase 1, mitochondrial | 1.4.1.3 | 0.463 | |
| 3ndc | SAH | Precorrin-4 C(11)-methyltransferase | 2.1.1.133 | 0.463 | |
| 4du8 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.463 | |
| 2huq | SAH | Diphthine synthase | / | 0.462 | |
| 2xyu | Q9G | Ephrin type-A receptor 4 | 2.7.10.1 | 0.462 | |
| 2q5p | 241 | Peroxisome proliferator-activated receptor gamma | / | 0.461 | |
| 3opd | HIE | Heat shock protein 83 | / | 0.461 | |
| 4ge4 | 0KE | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.461 | |
| 2hut | SAH | Diphthine synthase | / | 0.460 | |
| 2qbm | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.460 | |
| 3g45 | 988 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.460 | |
| 4aa4 | QC0 | Mitogen-activated protein kinase 14 | / | 0.460 | |
| 4ejm | NAP | Putative zinc-binding dehydrogenase | / | 0.460 | |
| 4tuv | CPZ | Cytochrome P450 119 | 1.14 | 0.460 | |
| 1cs4 | FOK | Adenylate cyclase type 2 | / | 0.459 | |
| 1cs4 | FOK | Adenylate cyclase type 5 | / | 0.459 | |
| 1ol7 | ADP | Aurora kinase A | 2.7.11.1 | 0.459 | |
| 4jhz | 1KV | Beta-glucuronidase | 3.2.1.31 | 0.459 | |
| 1cul | FOK | Adenylate cyclase type 2 | / | 0.458 | |
| 1cul | FOK | Adenylate cyclase type 5 | / | 0.458 | |
| 1g4t | FTP | Thiamine-phosphate synthase | / | 0.458 | |
| 2phk | ATP | Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform | 2.7.11.19 | 0.458 | |
| 4l4e | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.458 | |
| 1pd9 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.457 | |
| 2owu | SAH | Diphthine synthase | / | 0.457 | |
| 2vci | 2GJ | Heat shock protein HSP 90-alpha | / | 0.457 | |
| 2z3u | CRR | Cytochrome P450 | / | 0.457 | |
| 3a4v | NAD | NDP-sugar epimerase | / | 0.457 | |
| 3hx4 | ANP | Calmodulin-domain protein kinase 1 | / | 0.457 | |
| 1cjt | FOK | Adenylate cyclase type 2 | / | 0.456 | |
| 1cjt | FOK | Adenylate cyclase type 5 | / | 0.456 | |
| 1f17 | NAI | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.456 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.456 | |
| 1uyu | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.456 | |
| 3b20 | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.456 | |
| 3cge | COA | Coenzyme A disulfide reductase | / | 0.456 | |
| 4bcr | WY1 | Peroxisome proliferator-activated receptor alpha | / | 0.456 | |
| 2a94 | AP0 | L-lactate dehydrogenase | 1.1.1.27 | 0.455 | |
| 2p5f | SAH | Diphthine synthase | / | 0.455 | |
| 2wmu | ZYU | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.455 | |
| 2ww4 | ADP | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | 2.7.1.148 | 0.455 | |
| 3a1n | NAD | NDP-sugar epimerase | / | 0.455 | |
| 4egh | 0OY | Heat shock protein HSP 90-alpha | / | 0.455 | |
| 4ib4 | ERM | 5-hydroxytryptamine receptor 2B | / | 0.455 | |
| 4lht | CNL | 1,8-cineole 2-endo-monooxygenase | 1.14.13.156 | 0.455 | |
| 2dv4 | SAH | Diphthine synthase | / | 0.454 | |
| 2el0 | SAH | Diphthine synthase | / | 0.454 | |
| 2wyv | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.454 | |
| 3zh8 | C58 | Protein kinase C iota type | 2.7.11.13 | 0.454 | |
| 4nmd | FDA | Bifunctional protein PutA | / | 0.454 | |
| 2a1o | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.453 | |
| 2jcx | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | / | 0.453 | |
| 2p2x | SAH | Diphthine synthase | / | 0.453 | |
| 2ylx | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.453 | |
| 3otw | COA | Phosphopantetheine adenylyltransferase | / | 0.453 | |
| 4fak | SAM | Ribosomal RNA large subunit methyltransferase H | / | 0.453 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.453 | |
| 5ez7 | FAD | Probable FAD-dependent oxidoreductase PA4991 | / | 0.453 | |
| 1phh | FAD | p-hydroxybenzoate hydroxylase | / | 0.452 | |
| 1szj | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.452 | |
| 1ykd | CMP | Adenylate cyclase | / | 0.452 | |
| 2cgp | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.452 | |
| 2dv7 | SAH | Diphthine synthase | / | 0.452 | |
| 2q63 | 1UN | Gag-Pol polyprotein | 3.4.23.16 | 0.452 | |
| 2tps | TPS | Thiamine-phosphate synthase | / | 0.452 | |
| 3zuy | TCH | Transporter | / | 0.452 | |
| 4hbm | 0Y7 | E3 ubiquitin-protein ligase Mdm2 | 6.3.2 | 0.452 | |
| 4kip | 1R9 | Mitogen-activated protein kinase 14 | / | 0.452 | |
| 4q72 | FAD | Bifunctional protein PutA | / | 0.452 | |
| 4q73 | FAD | Bifunctional protein PutA | / | 0.452 | |
| 1cbf | SAH | Cobalt-precorrin-4 C(11)-methyltransferase | 2.1.1.271 | 0.451 | |
| 1fm6 | BRL | Peroxisome proliferator-activated receptor gamma | / | 0.451 | |
| 1mei | XMP | Inosine-5'-monophosphate dehydrogenase | / | 0.451 | |
| 1sxj | ADP | Replication factor C subunit 5 | / | 0.451 | |
| 1t2d | NAD | L-lactate dehydrogenase | 1.1.1.27 | 0.451 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.451 | |
| 2dv5 | SAH | Diphthine synthase | / | 0.451 | |
| 2ek2 | SAH | Diphthine synthase | / | 0.451 | |
| 2pcg | SAH | Diphthine synthase | / | 0.451 | |
| 2znp | K55 | Peroxisome proliferator-activated receptor delta | / | 0.451 | |
| 2zui | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.451 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.451 | |
| 4hgs | 15G | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.451 | |
| 4nd4 | NAD | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.451 | |
| 4neu | Q1A | Receptor-interacting serine/threonine-protein kinase 1 | 2.7.11.1 | 0.451 | |
| 4rcv | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | / | 0.451 | |
| 1g69 | TZP | Thiamine-phosphate synthase | / | 0.450 | |
| 1yrd | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.450 | |
| 2cgw | 3C3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.450 | |
| 2emr | SAH | Diphthine synthase | / | 0.450 | |
| 2znq | 401 | Peroxisome proliferator-activated receptor delta | / | 0.450 | |
| 4e37 | NDP | Catalase | 1.11.1.6 | 0.450 | |
| 4lsm | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.450 | |
| 5ar4 | SB2 | Receptor-interacting serine/threonine-protein kinase 2 | 2.7.11.1 | 0.450 | |
| 5koi | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.450 | |
| 1dhi | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 1eyq | NAR | Chalcone--flavonone isomerase 1 | 5.5.1.6 | 0.449 | |
| 1i7g | AZ2 | Peroxisome proliferator-activated receptor alpha | / | 0.449 | |
| 1sow | NAD | L-lactate dehydrogenase | 1.1.1.27 | 0.449 | |
| 2e07 | SAH | Diphthine synthase | / | 0.449 | |
| 2feu | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.449 | |
| 2gmh | FAD | Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial | 1.5.5.1 | 0.449 | |
| 2p5c | SAH | Diphthine synthase | / | 0.449 | |
| 2pcm | SAH | Diphthine synthase | / | 0.449 | |
| 2x0r | NAD | Malate dehydrogenase | / | 0.449 | |
| 2ym3 | YM3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.449 | |
| 3v1y | NAD | Glyceraldehyde-3-phosphate dehydrogenase 1, cytosolic | 1.2.1.12 | 0.449 | |
| 4aac | AAV | Mitogen-activated protein kinase 14 | / | 0.449 | |
| 4bb6 | HD1 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.449 | |
| 4hj6 | FMN | LOV protein | / | 0.449 | |
| 4y8w | STR | Steroid 21-hydroxylase | / | 0.449 | |
| 1dxq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.448 | |
| 1e5q | NDP | Saccharopine dehydrogenase [NADP(+), L-glutamate-forming] | 1.5.1.10 | 0.448 | |
| 1lsj | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.448 | |
| 1m76 | CAA | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.448 | |
| 1o76 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.448 | |
| 1v35 | NAI | Enoyl-ACP reductase | / | 0.448 | |
| 1zem | NAD | Xylitol dehydrogenase | / | 0.448 | |
| 2bdf | 24A | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.448 | |
| 2dv3 | SAH | Diphthine synthase | / | 0.448 | |
| 2ed5 | SAH | Diphthine synthase | / | 0.448 | |
| 2vcj | 2EQ | Heat shock protein HSP 90-alpha | / | 0.448 | |
| 3h6v | NS6 | Glutamate receptor 2 | / | 0.448 | |
| 3nwq | 2NC | Gag-Pol polyprotein | 3.4.23.16 | 0.448 | |
| 3qn8 | NI7 | Gag-Pol polyprotein | 3.4.23.16 | 0.448 | |
| 3tox | NAP | Putative oxidoreductase | / | 0.448 | |
| 4z07 | PCG | cGMP-dependent protein kinase 1 | 2.7.11.12 | 0.448 | |
| 1h69 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.447 | |
| 2cah | NDP | Catalase | 1.11.1.6 | 0.447 | |
| 2cgx | 3D3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.447 | |
| 2hr8 | SAH | Diphthine synthase | / | 0.447 | |
| 2owk | SAH | Diphthine synthase | / | 0.447 | |
| 2pca | SAH | Diphthine synthase | / | 0.447 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.447 | |
| 3cgc | FAD | Coenzyme A disulfide reductase | / | 0.447 | |
| 3cgd | COA | Coenzyme A disulfide reductase | / | 0.447 | |
| 3fp0 | FP0 | 15-O-acetyltransferase | / | 0.447 | |
| 3pwr | ROC | Gag-Pol polyprotein | 3.4.23.16 | 0.447 | |
| 3t11 | 3T1 | Gag-Pol polyprotein | 3.4.23.16 | 0.447 | |
| 4gyz | D5M | Tyrosyl-DNA phosphodiesterase 2 | 3.1.4 | 0.447 | |
| 4o63 | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.447 | |
| 5eyp | LOC | Tubulin beta chain | / | 0.447 | |
| 1boo | SAH | Modification methylase PvuII | 2.1.1.113 | 0.446 | |
| 2el3 | SAH | Diphthine synthase | / | 0.446 | |
| 2gqw | FAD | Ferredoxin reductase | / | 0.446 | |
| 2w3b | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 3f1k | NAP | Uncharacterized oxidoreductase YciK | 1 | 0.446 | |
| 3uic | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.446 | |
| 3vn2 | TLS | Peroxisome proliferator-activated receptor gamma | / | 0.446 | |
| 4xum | IMN | Peroxisome proliferator-activated receptor gamma | / | 0.446 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.445 | |
| 1bxk | NAD | dTDP-glucose 4,6-dehydratase 2 | / | 0.445 | |
| 1k6p | XN3 | Gag-Pol polyprotein | 3.4.23.16 | 0.445 | |
| 1k6t | XN1 | Gag-Pol polyprotein | 3.4.23.16 | 0.445 | |
| 1okz | UCN | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.445 | |
| 1t85 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.445 | |
| 2egs | SAH | Diphthine synthase | / | 0.445 | |
| 2eh4 | SAH | Diphthine synthase | / | 0.445 | |
| 2ek3 | SAH | Diphthine synthase | / | 0.445 | |
| 2g2z | COZ | Malonyl CoA-acyl carrier protein transacylase | 2.3.1.39 | 0.445 | |
| 2ivv | PP1 | Proto-oncogene tyrosine-protein kinase receptor Ret | 2.7.10.1 | 0.445 | |
| 2x2m | X2M | Proto-oncogene tyrosine-protein kinase receptor Ret | 2.7.10.1 | 0.445 | |
| 3gob | HXX | DdmC | / | 0.445 | |
| 3iae | D7K | Benzaldehyde lyase | / | 0.445 | |
| 3il1 | B5D | Glutamate receptor 2 | / | 0.445 | |
| 3inv | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.445 | |
| 3irm | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.445 | |
| 3oib | FDA | Putative acyl-CoA dehydrogenase | / | 0.445 | |
| 4c9p | CAM | Cytochrome P450 | / | 0.445 | |
| 4h3f | 10O | Beta-secretase 1 | 3.4.23.46 | 0.445 | |
| 4nbt | NAD | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.445 | |
| 4yr9 | NAD | L-threonine 3-dehydrogenase, mitochondrial | 1.1.1.103 | 0.445 | |
| 1k74 | 544 | Peroxisome proliferator-activated receptor gamma | / | 0.444 | |
| 1phe | PIY | Camphor 5-monooxygenase | 1.14.15.1 | 0.444 | |
| 1pzg | A3D | Lactate dehydrogenase | / | 0.444 | |
| 1teh | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.444 | |
| 2emu | SAH | Diphthine synthase | / | 0.444 | |
| 2oap | ANP | Type II secretion system protein (GspE-2) | / | 0.444 | |
| 2ou2 | ACO | Histone acetyltransferase KAT5 | / | 0.444 | |
| 2owv | SAH | Diphthine synthase | / | 0.444 | |
| 2wmx | ZY6 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.444 | |
| 2ylz | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.444 | |
| 3ada | NAD | Subunit alpha of sarocosine oxidase | / | 0.444 | |
| 3cgb | COA | Coenzyme A disulfide reductase | / | 0.444 | |
| 3iqi | ASN_GLU_ASN_ILE | Cysteine synthase | 2.5.1.47 | 0.444 | |
| 3s79 | ASD | Aromatase | 1.14.14.14 | 0.444 | |
| 3tki | S25 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.444 | |
| 3wrh | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.444 | |
| 4boy | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.444 | |
| 4ewn | 0VR | Imidazole glycerol phosphate synthase subunit HisF | 4.1.3 | 0.444 | |
| 4g95 | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 4ia7 | BIV | Vitamin D3 receptor A | / | 0.444 | |
| 1dz6 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 1h5q | NAP | NADP-dependent mannitol dehydrogenase | 1.1.1.138 | 0.443 | |
| 1j0x | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.443 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.443 | |
| 1owp | FAD | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.443 | |
| 1qbg | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.443 | |
| 2a1n | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 2acx | ANP | G protein-coupled receptor kinase 6 | 2.7.11.16 | 0.443 | |
| 2b53 | D23 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.443 | |
| 2b7a | IZA | Tyrosine-protein kinase JAK2 | / | 0.443 | |
| 2cmj | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.443 | |
| 2hma | SAM | tRNA-specific 2-thiouridylase MnmA | / | 0.443 | |
| 2r7b | 253 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.443 | |
| 2udp | UPP | UDP-glucose 4-epimerase | 5.1.3.2 | 0.443 | |
| 2wot | ZZG | TGF-beta receptor type-1 | 2.7.11.30 | 0.443 | |
| 3fwg | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 3nwx | KVS | Gag-Pol polyprotein | 3.4.23.16 | 0.443 | |
| 4an9 | 2P7 | Dual specificity mitogen-activated protein kinase kinase 1 | 2.7.12.2 | 0.443 | |
| 4dbv | NDP | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.443 | |
| 4fcq | 2N6 | Heat shock protein HSP 90-alpha | / | 0.443 | |
| 4gdy | 0X1 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.443 | |
| 4i8v | BHF | Cytochrome P450 1A1 | 1.14.14.1 | 0.443 | |
| 4kl9 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 4wuo | NAD | 3-isopropylmalate dehydrogenase | 1.1.1.85 | 0.443 | |
| 2e08 | SAH | Diphthine synthase | / | 0.442 | |
| 2e8h | SAH | Diphthine synthase | / | 0.442 | |
| 2egb | SAH | Diphthine synthase | / | 0.442 | |
| 2qbl | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 2rhg | IGP | Tryptophan synthase alpha chain | / | 0.442 | |
| 2znn | S44 | Peroxisome proliferator-activated receptor alpha | / | 0.442 | |
| 3b9l | AZZ | Serum albumin | / | 0.442 | |
| 3sqw | ANP | ATP-dependent RNA helicase MSS116, mitochondrial | 3.6.4.13 | 0.442 | |
| 3wrm | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 4cuk | NAI | D-lactate dehydrogenase | / | 0.442 | |
| 4enh | FVX | Cholesterol 24-hydroxylase | / | 0.442 | |
| 4euf | NAD | Trans-2-enoyl-CoA reductase [NADH] | / | 0.442 | |
| 4fsw | HK6 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.442 | |
| 4i8z | G08 | Gag-Pol polyprotein | 3.4.23.16 | 0.442 | |
| 4r8q | ADP | Mitotic checkpoint serine/threonine-protein kinase BUB1 | 2.7.11.1 | 0.442 | |
| 1nvq | UCN | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.441 | |
| 2ejk | SAH | Diphthine synthase | / | 0.441 | |
| 2en5 | SAH | Diphthine synthase | / | 0.441 | |
| 2ep7 | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.441 | |
| 2ghl | LIB | Mitogen-activated protein kinase 14 | / | 0.441 | |
| 2pch | SAH | Diphthine synthase | / | 0.441 | |
| 2xck | MH4 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.441 | |
| 3bhe | BZN | Gag-Pol polyprotein | 3.4.23.16 | 0.441 | |
| 3dmt | NAD | Glyceraldehyde-3-phosphate dehydrogenase, glycosomal | 1.2.1.12 | 0.441 | |
| 3qt6 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.441 | |
| 3u33 | FAD | Putative acyl-CoA dehydrogenase AidB | 1.3.99 | 0.441 | |
| 3uyt | 0CK | Casein kinase I isoform delta | 2.7.11.1 | 0.441 | |
| 3w4y | FAD | Mitochondrial FAD-linked sulfhydryl oxidase ERV1 | 1.8.3.2 | 0.441 | |
| 3zw9 | NAD | Peroxisomal bifunctional enzyme | 1.1.1.35 | 0.441 | |
| 4amb | DUD | Putative glycosyl transferase | / | 0.441 | |
| 4z61 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.441 | |
| 1byg | STU | Tyrosine-protein kinase CSK | / | 0.440 | |
| 1drh | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 1fm7 | DFV | Chalcone--flavonone isomerase 1 | 5.5.1.6 | 0.440 | |
| 1h65 | GDP | Translocase of chloroplast 34 | 3.6.5 | 0.440 | |
| 1hii | C20 | Gag-Pol polyprotein | / | 0.440 | |
| 1ie3 | NAD | Malate dehydrogenase | / | 0.440 | |
| 1k6c | MK1 | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
| 1kl2 | FON | Serine hydroxymethyltransferase | / | 0.440 | |
| 1olm | VTQ | SEC14-like protein 2 | / | 0.440 | |
| 1pl8 | NAD | Sorbitol dehydrogenase | 1.1.1.14 | 0.440 | |
| 1rek | B8L | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.440 | |
| 1t88 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 1y7l | ASN_LEU_ASN_ILE | Cysteine synthase | 2.5.1.47 | 0.440 | |
| 2e16 | SAH | Diphthine synthase | / | 0.440 | |
| 2e7z | MGD | Acetylene hydratase | / | 0.440 | |
| 2huv | SAH | Diphthine synthase | / | 0.440 | |
| 2ibz | UQ6 | Cytochrome b | / | 0.440 | |
| 2nru | T12 | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.440 | |
| 2q0l | FAD | Thioredoxin reductase | 1.8.1.9 | 0.440 | |
| 2v9j | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.440 | |
| 2ym5 | YM5 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.440 | |
| 2z6r | SAH | Diphthine synthase | / | 0.440 | |
| 2zaw | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 3ajr | NAD | NDP-sugar epimerase | / | 0.440 | |
| 3fwi | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 4ek1 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 4ftc | H6K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.440 | |
| 4ftu | 7HK | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.440 | |
| 4hbg | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | 1.1.1.100 | 0.440 | |
| 4iwq | 1FV | Serine/threonine-protein kinase TBK1 | 2.7.11.1 | 0.440 | |
| 4l4f | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 |