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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1ckpPVBCyclin-dependent kinase 22.7.11.22

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
1ckpPVBCyclin-dependent kinase 22.7.11.221.000
3s2pPMUCyclin-dependent kinase 22.7.11.220.627
2r64740Cyclin-dependent kinase 22.7.11.220.605
3qwjX6ACyclin-dependent kinase 22.7.11.220.593
3qtzX42Cyclin-dependent kinase 22.7.11.220.582
4fkpLS5Cyclin-dependent kinase 22.7.11.220.578
2xmyCDKCyclin-dependent kinase 22.7.11.220.560
1ke5LS1Cyclin-dependent kinase 22.7.11.220.557
3roy22ZCyclin-dependent kinase 22.7.11.220.557
3rjc06ZCyclin-dependent kinase 22.7.11.220.556
3qxoX65Cyclin-dependent kinase 22.7.11.220.554
3qu0X40Cyclin-dependent kinase 22.7.11.220.552
3r6xX84Cyclin-dependent kinase 22.7.11.220.552
2duv371Cyclin-dependent kinase 22.7.11.220.547
2vtiLZ3Cyclin-dependent kinase 22.7.11.220.544
3rpv26ZCyclin-dependent kinase 22.7.11.220.543
2btsU32Cyclin-dependent kinase 22.7.11.220.539
3r8lZ30Cyclin-dependent kinase 22.7.11.220.539
3rni21ZCyclin-dependent kinase 22.7.11.220.539
4ek610KCyclin-dependent kinase 22.7.11.220.539
2c6o4SPCyclin-dependent kinase 22.7.11.220.537
3ti1B49Cyclin-dependent kinase 22.7.11.220.534
2a0cCK9Cyclin-dependent kinase 22.7.11.220.533
3rk909ZCyclin-dependent kinase 22.7.11.220.533
1oitHDTCyclin-dependent kinase 22.7.11.220.532
4fkg4CKCyclin-dependent kinase 22.7.11.220.532
3r7vZ02Cyclin-dependent kinase 22.7.11.220.531
2btrU73Cyclin-dependent kinase 22.7.11.220.530
3r7yZ04Cyclin-dependent kinase 22.7.11.220.529
3r1yX76Cyclin-dependent kinase 22.7.11.220.528
1ke9LS5Cyclin-dependent kinase 22.7.11.220.527
1pxmCK5Cyclin-dependent kinase 22.7.11.220.527
3r9dX6BCyclin-dependent kinase 22.7.11.220.527
1g5sI17Cyclin-dependent kinase 22.7.11.220.526
3r1sX73Cyclin-dependent kinase 22.7.11.220.526
1ke7LS3Cyclin-dependent kinase 22.7.11.220.525
3lfnA27Cyclin-dependent kinase 22.7.11.220.525
3s1h56ZCyclin-dependent kinase 22.7.11.220.525
4fkv61KCyclin-dependent kinase 22.7.11.220.525
1y91CT9Cyclin-dependent kinase 22.7.11.220.524
2b52D42Cyclin-dependent kinase 22.7.11.220.524
4fkr45KCyclin-dependent kinase 22.7.11.220.524
4bgh3I6Cyclin-dependent kinase 22.7.11.220.523
3qtuX44Cyclin-dependent kinase 22.7.11.220.522
3rpo24ZCyclin-dependent kinase 22.7.11.220.522
3sqq99ZCyclin-dependent kinase 22.7.11.220.522
3rak03ZCyclin-dependent kinase 22.7.11.220.521
1e1xNW1Cyclin-dependent kinase 22.7.11.220.520
3qzhX69Cyclin-dependent kinase 22.7.11.220.520
2exmZIPCyclin-dependent kinase 22.7.11.220.519
3iggEFQCyclin-dependent kinase 22.7.11.220.519
3rm719ZCyclin-dependent kinase 22.7.11.220.519
4fkq42KCyclin-dependent kinase 22.7.11.220.519
2uzoC62Cyclin-dependent kinase 22.7.11.220.517
4ek816KCyclin-dependent kinase 22.7.11.220.517
4lyn1YGCyclin-dependent kinase 22.7.11.220.517
1ke6LS2Cyclin-dependent kinase 22.7.11.220.516
4acm7YGCyclin-dependent kinase 22.7.11.220.516
4fkj11KCyclin-dependent kinase 22.7.11.220.516
3qzgX67Cyclin-dependent kinase 22.7.11.220.515
4fkt48KCyclin-dependent kinase 22.7.11.220.515
1h1r6CPCyclin-dependent kinase 22.7.11.220.513
3r28XA0Cyclin-dependent kinase 22.7.11.220.513
3r83Z14Cyclin-dependent kinase 22.7.11.220.513
3r8vZ62Cyclin-dependent kinase 22.7.11.220.513
3rm618ZCyclin-dependent kinase 22.7.11.220.513
1p2a5BNCyclin-dependent kinase 22.7.11.220.512
3ezvEZVCyclin-dependent kinase 22.7.11.220.512
1b38ATPCyclin-dependent kinase 22.7.11.220.511
3ig7EFPCyclin-dependent kinase 22.7.11.220.511
2vtpLZ9Cyclin-dependent kinase 22.7.11.220.510
3qqkX02Cyclin-dependent kinase 22.7.11.220.510
1gih1PUCyclin-dependent kinase 22.7.11.220.507
3r71X86Cyclin-dependent kinase 22.7.11.220.507
4bcpT3CCyclin-dependent kinase 22.7.11.220.507
3pj8404Cyclin-dependent kinase 22.7.11.220.506
3r9hZ67Cyclin-dependent kinase 22.7.11.220.505
2uznC96Cyclin-dependent kinase 22.7.11.220.504
2w05FRTCyclin-dependent kinase 22.7.11.220.504
3r73X87Cyclin-dependent kinase 22.7.11.220.504
4eor4SPCyclin-dependent kinase 22.7.11.220.504
1ke8LS4Cyclin-dependent kinase 22.7.11.220.503
4fki09KCyclin-dependent kinase 22.7.11.220.502
3raiX85Cyclin-dependent kinase 22.7.11.220.501
3rmf20ZCyclin-dependent kinase 22.7.11.220.501
1fvt106Cyclin-dependent kinase 22.7.11.220.500
1h1s4SPCyclin-dependent kinase 22.7.11.220.500
3ddpRC8Cyclin-dependent kinase 22.7.11.220.500
3r9oZ71Cyclin-dependent kinase 22.7.11.220.500
4fks46KCyclin-dependent kinase 22.7.11.220.500
1di8DTQCyclin-dependent kinase 22.7.11.220.499
2a4lRRCCyclin-dependent kinase 22.7.11.220.498
3qqlX03Cyclin-dependent kinase 22.7.11.220.496
3qwkX62Cyclin-dependent kinase 22.7.11.220.496
4fx360KCyclin-dependent kinase 22.7.11.220.496
2r3gSC9Cyclin-dependent kinase 22.7.11.220.495
3lfqA28Cyclin-dependent kinase 22.7.11.220.495
2w06FRVCyclin-dependent kinase 22.7.11.220.494
1v1k3FPCyclin-dependent kinase 22.7.11.220.493
3rk708ZCyclin-dependent kinase 22.7.11.220.493
4eon1ROCyclin-dependent kinase 22.7.11.220.493
1h0vUN4Cyclin-dependent kinase 22.7.11.220.492
1pxlCK4Cyclin-dependent kinase 22.7.11.220.492
3ddqRRCCyclin-dependent kinase 22.7.11.220.492
3unj0BXCyclin-dependent kinase 22.7.11.220.492
3sw418KCyclin-dependent kinase 22.7.11.220.491
1vyzN5BCyclin-dependent kinase 22.7.11.220.490
3lfsA07Cyclin-dependent kinase 22.7.11.220.490
3qx2X63Cyclin-dependent kinase 22.7.11.220.490
1oi9N20Cyclin-dependent kinase 22.7.11.220.489
1ykr628Cyclin-dependent kinase 22.7.11.220.489
4fkw62KCyclin-dependent kinase 22.7.11.220.489
1unlRRCCyclin-dependent-like kinase 52.7.11.10.488
3r7uX96Cyclin-dependent kinase 22.7.11.220.488
1w8cN69Cyclin-dependent kinase 22.7.11.220.487
1aq1STUCyclin-dependent kinase 22.7.11.220.486
1pxoCK7Cyclin-dependent kinase 22.7.11.220.486
1urwI1PCyclin-dependent kinase 22.7.11.220.485
2iw84SPCyclin-dependent kinase 22.7.11.220.485
3ral04ZCyclin-dependent kinase 22.7.11.220.485
1v0pPVBCell division control protein 2 homolog2.7.11.220.483
2b55D31Cyclin-dependent kinase 22.7.11.220.482
2iw94SPCyclin-dependent kinase 22.7.11.220.481
3rahO1ZCyclin-dependent kinase 22.7.11.220.481
2bheBRYCyclin-dependent kinase 22.7.11.220.480
3fz1B98Cyclin-dependent kinase 22.7.11.220.480
3qruX19Cyclin-dependent kinase 22.7.11.220.480
4ez30S0Cyclin-dependent kinase 22.7.11.220.480
1b39ATPCyclin-dependent kinase 22.7.11.220.479
3rkb12ZCyclin-dependent kinase 22.7.11.220.479
2r3lSCWCyclin-dependent kinase 22.7.11.220.478
3py0SU9Cyclin-dependent kinase 22.7.11.220.478
1dm2HMDCyclin-dependent kinase 22.7.11.220.477
3ql8X01Cyclin-dependent kinase 22.7.11.220.477
2wpa889Cyclin-dependent kinase 22.7.11.220.476
3qqhX0ACyclin-dependent kinase 22.7.11.220.476
3r8pZ46Cyclin-dependent kinase 22.7.11.220.476
2bhhRYUCyclin-dependent kinase 22.7.11.220.475
2r3kSCQCyclin-dependent kinase 22.7.11.220.475
2vthLZ2Cyclin-dependent kinase 22.7.11.220.475
2vv9IM9Cyclin-dependent kinase 22.7.11.220.475
2w1hL0FCyclin-dependent kinase 22.7.11.220.475
3qtrX36Cyclin-dependent kinase 22.7.11.220.475
4bcoT6QCyclin-dependent kinase 22.7.11.220.475
1hckATPCyclin-dependent kinase 22.7.11.220.474
2j9mPY8Cyclin-dependent kinase 22.7.11.220.474
3rk507ZCyclin-dependent kinase 22.7.11.220.474
5aniES4Cyclin-dependent kinase 22.7.11.220.474
3qqfX07Cyclin-dependent kinase 22.7.11.220.473
4fko20KCyclin-dependent kinase 22.7.11.220.473
1oguST8Cyclin-dependent kinase 22.7.11.220.472
1w0xOLOCyclin-dependent kinase 22.7.11.220.472
4kd11QKCyclin-dependent kinase 22.7.11.220.472
2fvdLIACyclin-dependent kinase 22.7.11.220.471
2vtoLZ8Cyclin-dependent kinase 22.7.11.220.470
1h1q2A6Cyclin-dependent kinase 22.7.11.220.469
3ezrEZRCyclin-dependent kinase 22.7.11.220.469
1pxkCK3Cyclin-dependent kinase 22.7.11.220.468
2vu3LZECyclin-dependent kinase 22.7.11.220.468
3qtxX43Cyclin-dependent kinase 22.7.11.220.468
3r1qX75Cyclin-dependent kinase 22.7.11.220.468
2c6iDT1Cyclin-dependent kinase 22.7.11.220.467
2r3r6SCCyclin-dependent kinase 22.7.11.220.467
3qxpX64Cyclin-dependent kinase 22.7.11.220.467
1h0w207Cyclin-dependent kinase 22.7.11.220.465
1oiqHDUCyclin-dependent kinase 22.7.11.220.465
1r78FMDCyclin-dependent kinase 22.7.11.220.465
2vtjLZ4Cyclin-dependent kinase 22.7.11.220.465
3s0o50ZCyclin-dependent kinase 22.7.11.220.465
2iw6QQ2Cyclin-dependent kinase 22.7.11.220.464
1vyw292Cyclin-dependent kinase 22.7.11.220.463
2vtsLZCCyclin-dependent kinase 22.7.11.220.463
3unk0BYCyclin-dependent kinase 22.7.11.220.463
4cfnJYMCyclin-dependent kinase 22.7.11.220.462
1oiyN41Cyclin-dependent kinase 22.7.11.220.461
2wotZZGTGF-beta receptor type-12.7.11.300.461
3qrtX14Cyclin-dependent kinase 22.7.11.220.461
1oiuN76Cyclin-dependent kinase 22.7.11.220.459
2c69CT8Cyclin-dependent kinase 22.7.11.220.459
3wblPDYCyclin-dependent kinase 22.7.11.220.459
2c4g514Cyclin-dependent kinase 22.7.11.220.458
4bcnT9NCyclin-dependent kinase 22.7.11.220.458
2r3iSCFCyclin-dependent kinase 22.7.11.220.457
2w17I19Cyclin-dependent kinase 22.7.11.220.457
2x1nX1NCyclin-dependent kinase 22.7.11.220.457
2wxvWXVCyclin-dependent kinase 22.7.11.220.455
3r7eX88Cyclin-dependent kinase 22.7.11.220.455
2r3p3SCCyclin-dependent kinase 22.7.11.220.454
3cic316Beta-secretase 13.4.23.460.453
3rpy27ZCyclin-dependent kinase 22.7.11.220.452
1e9hINRCyclin-dependent kinase 22.7.11.220.451
1pyePM1Cyclin-dependent kinase 22.7.11.220.451
2c5nCK8Cyclin-dependent kinase 22.7.11.220.451
2xnbY8LCyclin-dependent kinase 22.7.11.220.451
1qmzATPCyclin-dependent kinase 22.7.11.220.450
4eop1ROCyclin-dependent kinase 22.7.11.220.450
2vtnLZ7Cyclin-dependent kinase 22.7.11.220.449
3s00Z60Cyclin-dependent kinase 22.7.11.220.449
3sayOFTGlycogen synthase kinase-3 beta2.7.11.260.449
4nj32KDCyclin-dependent kinase 22.7.11.220.448
1h1pCMGCyclin-dependent kinase 22.7.11.220.447
2vtlLZ5Cyclin-dependent kinase 22.7.11.220.447
3dogNNNCyclin-dependent kinase 22.7.11.220.446
3bhtMFRCyclin-dependent kinase 22.7.11.220.445
3qx4X4BCyclin-dependent kinase 22.7.11.220.445
3o0g3O0Cyclin-dependent-like kinase 52.7.11.10.444
4eoi1ROCyclin-dependent kinase 22.7.11.220.444
4flh14KPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.444
3v5l0G1Tyrosine-protein kinase ITK/TSK2.7.10.20.443
4eos1ROCyclin-dependent kinase 22.7.11.220.443
2c6mDT5Cyclin-dependent kinase 22.7.11.220.442
3axwTIDCasein kinase II subunit alpha2.7.11.10.442
3uli1N3Cyclin-dependent kinase 22.7.11.220.442
4eok4SPCyclin-dependent kinase 22.7.11.220.442
1gii1PUCyclin-dependent kinase 22.7.11.220.441
2b53D23Cyclin-dependent kinase 22.7.11.220.441
2c6kDT2Cyclin-dependent kinase 22.7.11.220.441
2r3o2SCCyclin-dependent kinase 22.7.11.220.441
1pxpCK8Cyclin-dependent kinase 22.7.11.220.440
3qziX72Cyclin-dependent kinase 22.7.11.220.440
4anmWULCasein kinase II subunit alpha2.7.11.10.440