sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 5hwr | COA | Hydroxymethylglutaryl-CoA synthase |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 5hwr | COA | Hydroxymethylglutaryl-CoA synthase | / | 1.000 | |
| 5hwo | HMG | Hydroxymethylglutaryl-CoA synthase | / | 0.768 | |
| 5hwp | COA | Hydroxymethylglutaryl-CoA synthase | / | 0.681 | |
| 5hwq | CAA | Hydroxymethylglutaryl-CoA synthase | / | 0.616 | |
| 2wya | HMG | Hydroxymethylglutaryl-CoA synthase, mitochondrial | 2.3.3.10 | 0.589 | |
| 1txt | CAA | HMG-CoA synthase | / | 0.574 | |
| 2p8u | COA | Hydroxymethylglutaryl-CoA synthase, cytoplasmic | 2.3.3.10 | 0.542 | |
| 3sqz | COA | Putative hydroxymethylglutaryl-CoA synthase | / | 0.514 | |
| 4twn | B96 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.499 | |
| 4cvm | ANP | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase | / | 0.495 | |
| 2j3j | HC4 | NADPH-dependent oxidoreductase 2-alkenal reductase | 1.3.1.74 | 0.488 | |
| 1vbi | NAD | Malate/L-lactate dehydrogenase family protein | / | 0.487 | |
| 2g8y | NAD | Hydroxycarboxylate dehydrogenase B | / | 0.482 | |
| 2gv8 | NDP | Thiol-specific monooxygenase | 1.14.13 | 0.482 | |
| 3k3h | BYE | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.477 | |
| 2cib | CM6 | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.475 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.475 | |
| 1rfv | ADP | Pyridoxal kinase | 2.7.1.35 | 0.474 | |
| 1ysl | COA | Hydroxymethylglutaryl-CoA synthase | 2.3.3.10 | 0.474 | |
| 2fm5 | M99 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.474 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.474 | |
| 3uyl | TYD | Probable NDP-rhamnosyltransferase | / | 0.473 | |
| 2y0m | ACO | Histone acetyltransferase KAT8 | / | 0.472 | |
| 3bxx | QUE | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.472 | |
| 4amb | DUD | Putative glycosyl transferase | / | 0.472 | |
| 5dmh | ADP | 3-oxo-tetronate kinase | / | 0.472 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.471 | |
| 4oxy | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.469 | |
| 1upw | 444 | Oxysterols receptor LXR-beta | / | 0.468 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.468 | |
| 4fw8 | NAI | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.468 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.468 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.467 | |
| 4b14 | 4XB | Glycylpeptide N-tetradecanoyltransferase | / | 0.467 | |
| 4z61 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.467 | |
| 2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.465 | |
| 4yai | NAI | C alpha-dehydrogenase | / | 0.465 | |
| 1r5h | AO2 | Methionine aminopeptidase 2 | / | 0.464 | |
| 4uyf | 73B | Bromodomain-containing protein 2 | / | 0.464 | |
| 2xvw | 9NR | Serum albumin | / | 0.463 | |
| 1cul | FOK | Adenylate cyclase type 2 | / | 0.462 | |
| 1cul | FOK | Adenylate cyclase type 5 | / | 0.462 | |
| 1psa | 0ZL | Pepsin A | 3.4.23.1 | 0.462 | |
| 2dv3 | SAH | Diphthine synthase | / | 0.462 | |
| 1ay0 | TPP | Transketolase 1 | 2.2.1.1 | 0.461 | |
| 1drh | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.461 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.461 | |
| 2ym2 | NAP | Phenylacetone monooxygenase | 1.14.13.92 | 0.461 | |
| 3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.461 | |
| 3pqb | VGP | Putative oxidoreductase | / | 0.461 | |
| 3b9o | FMN | Alkane monoxygenase | / | 0.460 | |
| 1adf | TAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.459 | |
| 1xom | CIO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.459 | |
| 2wo7 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.459 | |
| 3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.459 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.459 | |
| 4xcv | NDP | Probable hydroxyacid dehydrogenase protein | / | 0.459 | |
| 1d4a | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.458 | |
| 2e15 | SAH | Diphthine synthase | / | 0.458 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.458 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.458 | |
| 4ead | 0NP | Thymidine phosphorylase | 2.4.2.4 | 0.458 | |
| 4mlp | 2CX | Cryptochrome-2 | / | 0.458 | |
| 5dp2 | NAP | CurF | / | 0.458 | |
| 2jj2 | ANP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.457 | |
| 3nbv | ANP | Ketohexokinase | / | 0.457 | |
| 3tne | RIT | Candidapepsin-1 | 3.4.23.24 | 0.457 | |
| 4ri1 | ACO | UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine N-acetyltransferase | 2.3.1.202 | 0.457 | |
| 4wdb | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.457 | |
| 1dxo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.456 | |
| 1h69 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.456 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.456 | |
| 2z6r | SAH | Diphthine synthase | / | 0.456 | |
| 3dy8 | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.456 | |
| 3vdq | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.456 | |
| 4jx1 | CAH | Camphor 5-monooxygenase | 1.14.15.1 | 0.456 | |
| 4nxx | GDP | Mitochondrial dynamics protein MID51 | / | 0.456 | |
| 4u9a | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.456 | |
| 1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.455 | |
| 2bu9 | HFV | Isopenicillin N synthase | 1.21.3.1 | 0.455 | |
| 2hdj | NDP | Aldo-keto reductase family 1 member C2 | / | 0.455 | |
| 3h3q | H13 | Collagen type IV alpha-3-binding protein | / | 0.455 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.455 | |
| 1lf2 | R37 | Plasmepsin-2 | 3.4.23.39 | 0.454 | |
| 1uzw | CDH | Isopenicillin N synthase | 1.21.3.1 | 0.454 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.454 | |
| 3d7z | GK5 | Mitogen-activated protein kinase 14 | / | 0.454 | |
| 3ft8 | MOJ | Heat shock protein HSP 90-alpha | / | 0.454 | |
| 3g5s | FAD | Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO | / | 0.454 | |
| 3lpk | Z76 | Beta-secretase 1 | 3.4.23.46 | 0.454 | |
| 4eak | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.454 | |
| 1kr2 | TAD | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 | 2.7.7.1 | 0.453 | |
| 1me6 | IVS | Plasmepsin-2 | 3.4.23.39 | 0.453 | |
| 2ouu | 35G | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.453 | |
| 3b6z | CO7 | Enoyl reductase LovC | 1 | 0.453 | |
| 3cib | 314 | Beta-secretase 1 | 3.4.23.46 | 0.453 | |
| 3k5g | BJC | Beta-secretase 1 | 3.4.23.46 | 0.453 | |
| 4j8t | DOG | Uncharacterized PhzA/B-like protein PA3332 | / | 0.453 | |
| 1blz | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.452 | |
| 1uym | PU3 | Heat shock protein HSP 90-beta | / | 0.452 | |
| 2pg0 | FAD | Acyl-CoA dehydrogenase | / | 0.452 | |
| 2q2v | NAD | Beta-D-hydroxybutyrate dehydrogenase | / | 0.452 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.452 | |
| 2x7h | PFN | Prostaglandin reductase 3 | 1 | 0.452 | |
| 3qi4 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.452 | |
| 3t3r | 9PL | Cytochrome P450 2A6 | 1.14.13 | 0.452 | |
| 4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.452 | |
| 1ib0 | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.451 | |
| 2wez | ZYE | Beta-secretase 1 | 3.4.23.46 | 0.451 | |
| 2wyv | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.451 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.451 | |
| 3hbb | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.451 | |
| 4bft | ZVT | Pantothenate kinase | 2.7.1.33 | 0.451 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.451 | |
| 5irn | ADP | Nucleotide binding oligomerization domain containing 2 | / | 0.451 | |
| 1h50 | FMN | Pentaerythritol tetranitrate reductase | / | 0.450 | |
| 1kvk | ATP | Mevalonate kinase | 2.7.1.36 | 0.450 | |
| 1q0r | AKT | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.450 | |
| 1u4o | NDD | L-lactate dehydrogenase | 1.1.1.27 | 0.450 | |
| 2c29 | NAP | Dihydroflavonol 4-reductase | / | 0.450 | |
| 2xvv | 9DN | Serum albumin | / | 0.450 | |
| 3dyq | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.450 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.450 | |
| 3lpi | Z74 | Beta-secretase 1 | 3.4.23.46 | 0.450 | |
| 3zxz | KRW | Hepatocyte growth factor receptor | 2.7.10.1 | 0.450 | |
| 4hy6 | FJ1 | Heat shock protein HSP 90-alpha | / | 0.450 | |
| 4l9k | EHF | Serum albumin | / | 0.450 | |
| 4r81 | FMN | Predicted NADH dehydrogenase | / | 0.450 | |
| 5c77 | SAH | Protein arginine N-methyltransferase SFM1 | / | 0.450 | |
| 5ej9 | TPP | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.450 | |
| 5jla | NAD | Putative short-chain dehydrogenase/reductase | / | 0.450 | |
| 1gg5 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.449 | |
| 1r2j | FAD | FkbI | / | 0.449 | |
| 1uye | PU9 | Heat shock protein HSP 90-alpha | / | 0.449 | |
| 3qe2 | FMN | NADPH--cytochrome P450 reductase | / | 0.449 | |
| 3uzw | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.449 | |
| 4e90 | 7RG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.449 | |
| 5fl3 | ADP | Pili retraction protein PilT | / | 0.449 | |
| 1h5q | NAP | NADP-dependent mannitol dehydrogenase | 1.1.1.138 | 0.448 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.448 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.448 | |
| 2a0x | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.448 | |
| 2p6l | SAH | Diphthine synthase | / | 0.448 | |
| 3bv7 | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.448 | |
| 3da2 | 4MD | Carbonic anhydrase 13 | 4.2.1.1 | 0.448 | |
| 3ibd | CPZ | Cytochrome P450 2B6 | 1.14.13 | 0.448 | |
| 3ohh | 3HH | Beta-secretase 1 | 3.4.23.46 | 0.448 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.448 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.448 | |
| 4bca | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.448 | |
| 4bcr | WY1 | Peroxisome proliferator-activated receptor alpha | / | 0.448 | |
| 4bfs | ZVS | Pantothenate kinase | 2.7.1.33 | 0.448 | |
| 4ipw | 1G7 | Mycocyclosin synthase | 1.14.21.9 | 0.448 | |
| 4ozt | P1A | Ecdysone receptor, putative | / | 0.448 | |
| 4q73 | FAD | Bifunctional protein PutA | / | 0.448 | |
| 1h51 | FMN | Pentaerythritol tetranitrate reductase | / | 0.447 | |
| 1hyg | NAP | L-2-hydroxycarboxylate dehydrogenase (NAD(P)(+)) | / | 0.447 | |
| 1kqw | RTL | Cellular retinol-binding protein type II | / | 0.447 | |
| 1rfu | ADP | Pyridoxal kinase | 2.7.1.35 | 0.447 | |
| 2e0n | SAH | Precorrin-2 C20-methyltransferase | / | 0.447 | |
| 2fa3 | ACO | Hydroxymethylglutaryl-CoA synthase | / | 0.447 | |
| 2g78 | REA | Cellular retinoic acid-binding protein 2 | / | 0.447 | |
| 3jsi | WTC | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.447 | |
| 3k3e | PDB | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.447 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.446 | |
| 1qzy | TDE | Methionine aminopeptidase 2 | / | 0.446 | |
| 1r5g | AO1 | Methionine aminopeptidase 2 | / | 0.446 | |
| 2eeq | SAH | Diphthine synthase | / | 0.446 | |
| 2ejz | SAH | Diphthine synthase | / | 0.446 | |
| 2ekp | NAD | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.446 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.446 | |
| 2y6f | M9F | Isopenicillin N synthase | 1.21.3.1 | 0.446 | |
| 3f03 | FMN | Pentaerythritol tetranitrate reductase | / | 0.446 | |
| 3kjr | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.446 | |
| 3tox | NAP | Putative oxidoreductase | / | 0.446 | |
| 3vf6 | 0H6 | Glucokinase | 2.7.1.2 | 0.446 | |
| 4ap1 | NAP | Steroid monooxygenase | / | 0.446 | |
| 4dc1 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.446 | |
| 4eag | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.446 | |
| 1fml | RTL | Retinol dehydratase | / | 0.445 | |
| 1gee | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.445 | |
| 1iy8 | NAD | Levodione reductase | / | 0.445 | |
| 1kbo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.445 | |
| 1kce | CB3 | Thymidylate synthase | / | 0.445 | |
| 1rx0 | FAD | Isobutyryl-CoA dehydrogenase, mitochondrial | 1.3.99 | 0.445 | |
| 1u3d | FAD | Cryptochrome-1 | / | 0.445 | |
| 1u7t | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.445 | |
| 1xon | PIL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.445 | |
| 1y2k | 7DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.445 | |
| 2il2 | LIX | Renin | 3.4.23.15 | 0.445 | |
| 2owu | SAH | Diphthine synthase | / | 0.445 | |
| 2rlc | CHD | Choloylglycine hydrolase | 3.5.1.24 | 0.445 | |
| 3duy | AFJ | Beta-secretase 1 | 3.4.23.46 | 0.445 | |
| 3oqu | A8S | Abscisic acid receptor PYL9 | / | 0.445 | |
| 3uoy | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.445 | |
| 1a72 | PAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.444 | |
| 1bim | 0QB | Renin | 3.4.23.15 | 0.444 | |
| 1f5f | DHT | Sex hormone-binding globulin | / | 0.444 | |
| 1qjf | ACS | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
| 1t9g | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.444 | |
| 1tys | TMP | Thymidylate synthase | / | 0.444 | |
| 1x7h | NDP | Putative ketoacyl reductase | 1.3.1 | 0.444 | |
| 2h55 | DZ8 | Heat shock protein HSP 90-alpha | / | 0.444 | |
| 2huv | SAH | Diphthine synthase | / | 0.444 | |
| 2i4j | DRJ | Peroxisome proliferator-activated receptor gamma | / | 0.444 | |
| 2iod | MYC | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.444 | |
| 2oz5 | 7XY | Uncharacterized protein | / | 0.444 | |
| 2wdz | NAD | Galactitol dehydrogenase | / | 0.444 | |
| 2ztl | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.444 | |
| 3b9l | AZZ | Serum albumin | / | 0.444 | |
| 3hl0 | NAD | Maleylacetate reductase | / | 0.444 | |
| 4an4 | DUD | Putative glycosyl transferase | / | 0.444 | |
| 4h8n | NDP | NADPH-dependent conjugated polyketone reductase C2 | / | 0.444 | |
| 4i5e | NAP | Alclohol dehydrogenase/short-chain dehydrogenase | / | 0.444 | |
| 4i8x | 6P3 | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.444 | |
| 4n3r | 2GU | Tankyrase-1 | 2.4.2.30 | 0.444 | |
| 4nxu | ADP | Mitochondrial dynamics protein MID51 | / | 0.444 | |
| 4tuv | CPZ | Cytochrome P450 119 | 1.14 | 0.444 | |
| 5dld | UD1 | UDP-N-Acetylglucosamine 2-epimerase | / | 0.444 | |
| 1fm4 | DXC | Major pollen allergen Bet v 1-L | / | 0.443 | |
| 1hb3 | SCV | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
| 1n2s | NAI | dTDP-4-dehydrorhamnose reductase | 1.1.1.133 | 0.443 | |
| 1q0z | AKA | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.443 | |
| 2c1z | U2F | Anthocyanidin 3-O-glucosyltransferase 2 | 2.4.1.115 | 0.443 | |
| 2nry | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.443 | |
| 2z6c | FMN | Phototropin-1 | 2.7.11.1 | 0.443 | |
| 3gw9 | VNI | Lanosterol 14-alpha-demethylase | / | 0.443 | |
| 3o6o | 94M | Heat shock protein 83 | / | 0.443 | |
| 3oet | NAD | Erythronate-4-phosphate dehydrogenase | / | 0.443 | |
| 4ku5 | DCC | 3-oxoacyl-[ACP] synthase III | / | 0.443 | |
| 5a3b | APR | SIR2 family protein | / | 0.443 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
| 1ia1 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1mkd | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.442 | |
| 1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.442 | |
| 1rwb | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.442 | |
| 1teh | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.442 | |
| 2dv7 | SAH | Diphthine synthase | / | 0.442 | |
| 2o1s | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.442 | |
| 2ydv | NEC | Adenosine receptor A2a | / | 0.442 | |
| 3dhe | AND | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.442 | |
| 3mpj | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.442 | |
| 4nbt | NAD | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.442 | |
| 4wdf | A2P | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.442 | |
| 5jqh | CAU | Beta-2 adrenergic receptor | / | 0.442 | |
| 1gco | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.441 | |
| 2a4x | BLM | Mitomycin-binding protein | / | 0.441 | |
| 2egl | SAH | Diphthine synthase | / | 0.441 | |
| 2giv | ACO | Histone acetyltransferase KAT8 | / | 0.441 | |
| 2gqp | PA7 | Endoplasmin | / | 0.441 | |
| 2p6k | SAH | Diphthine synthase | / | 0.441 | |
| 3ada | NAD | Subunit alpha of sarocosine oxidase | / | 0.441 | |
| 3cls | FAD | Electron transfer flavoprotein subunit alpha | / | 0.441 | |
| 3h3s | H15 | Collagen type IV alpha-3-binding protein | / | 0.441 | |
| 3oib | FDA | Putative acyl-CoA dehydrogenase | / | 0.441 | |
| 3up4 | NAP | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.441 | |
| 3w0c | 6DS | Vitamin D3 receptor | / | 0.441 | |
| 4a31 | 2CB | Glycylpeptide N-tetradecanoyltransferase | / | 0.441 | |
| 4a32 | 2CD | Glycylpeptide N-tetradecanoyltransferase | / | 0.441 | |
| 4iar | ERM | 5-hydroxytryptamine receptor 1B | / | 0.441 | |
| 4qi5 | FAD | Cellobiose dehydrogenase | / | 0.441 | |
| 4rhe | FMN | Flavin prenyltransferase UbiX | / | 0.441 | |
| 4wda | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.441 | |
| 4yvk | SFG | tRNA (guanine-N(1)-)-methyltransferase | 2.1.1.228 | 0.441 | |
| 1j7k | ATP | Holliday junction ATP-dependent DNA helicase RuvB | / | 0.440 | |
| 1so2 | 666 | cGMP-inhibited 3',5'-cyclic phosphodiesterase B | 3.1.4.17 | 0.440 | |
| 1y2c | 3DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.440 | |
| 2a0w | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.440 | |
| 2c1b | CQP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.440 | |
| 2dra | ATP | CCA-adding enzyme | 2.7.7.72 | 0.440 | |
| 2dv5 | SAH | Diphthine synthase | / | 0.440 | |
| 2fw3 | BUI | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.440 | |
| 2g24 | 7IG | Renin | 3.4.23.15 | 0.440 | |
| 2iku | LIY | Renin | 3.4.23.15 | 0.440 | |
| 2p9d | SAH | Diphthine synthase | / | 0.440 | |
| 2qd4 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.440 | |
| 2yne | YNE | Glycylpeptide N-tetradecanoyltransferase | / | 0.440 | |
| 3a1c | ACP | Probable copper-exporting P-type ATPase A | 3.6.3.54 | 0.440 | |
| 3dyn | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.440 | |
| 3f3s | NAD | Lambda-crystallin homolog | / | 0.440 | |
| 3sf6 | FDA | Glutaryl-CoA dehydrogenase | / | 0.440 | |
| 3uic | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.440 | |
| 4anx | 534 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.440 | |
| 4b13 | X25 | Glycylpeptide N-tetradecanoyltransferase | / | 0.440 | |
| 4dvi | 2IW | Tankyrase-1 | 2.4.2.30 | 0.440 | |
| 4g7g | VFV | Lanosterol 14-alpha-demethylase | / | 0.440 | |
| 4gh6 | LUO | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.440 | |
| 4pl0 | ANP | Microcin-J25 export ATP-binding/permease protein McjD | / | 0.440 | |
| 4plp | NAD | Homospermidine synthase | 2.5.1.44 | 0.440 | |
| 4u0m | GTP | Cyclic GMP-AMP synthase | / | 0.440 | |
| 4uwm | FMN | 3,6-diketocamphane 1,6 monooxygenase | 1.14.13 | 0.440 | |
| 5js6 | NAD | 17-beta-hydroxysteroid dehydrogenase 14 | 1.1.1 | 0.440 |