Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4mxz | DB8 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 4mxy | DB8 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 1.000 | |
| 4mxz | DB8 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 1.000 | |
| 4dgg | I76 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.579 | |
| 3vs7 | KS1 | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.565 | |
| 4bc6 | XZN | Serine/threonine-protein kinase 10 | 2.7.11.1 | 0.563 | |
| 1qpj | STU | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.561 | |
| 3qlg | 1N1 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.557 | |
| 4mxo | DB8 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.548 | |
| 3qlf | PD5 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.545 | |
| 3b2w | 9NH | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.543 | |
| 4gk4 | L90 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.542 | |
| 3w2s | W2R | Epidermal growth factor receptor | 2.7.10.1 | 0.538 | |
| 2zm1 | KSF | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.536 | |
| 2of2 | 547 | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.530 | |
| 2c6e | HPM | Aurora kinase A | 2.7.11.1 | 0.528 | |
| 3vs6 | VSH | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.527 | |
| 4nka | 2K7 | Fibroblast growth factor receptor 1 | / | 0.526 | |
| 2c0i | L1G | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.525 | |
| 2hk5 | 1BM | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.525 | |
| 4nks | 2M2 | Fibroblast growth factor receptor 1 | / | 0.525 | |
| 3cjg | KIM | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.523 | |
| 2c0t | L3G | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.522 | |
| 2pwl | ACP | Fibroblast growth factor receptor 2 | / | 0.521 | |
| 4aot | GW8 | Serine/threonine-protein kinase 10 | 2.7.11.1 | 0.521 | |
| 3w2o | 03P | Epidermal growth factor receptor | 2.7.10.1 | 0.520 | |
| 4id7 | 1G0 | Activated CDC42 kinase 1 | / | 0.520 | |
| 3vrz | VRZ | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.518 | |
| 4l7s | G7K | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.517 | |
| 2j7t | 274 | Serine/threonine-protein kinase 10 | 2.7.11.1 | 0.516 | |
| 4mxx | DB8 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.516 | |
| 1yol | S03 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.515 | |
| 2xvd | AS6 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.515 | |
| 4f64 | 0S8 | Fibroblast growth factor receptor 1 | / | 0.515 | |
| 4gk2 | L66 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.515 | |
| 4joa | 3DK | ALK tyrosine kinase receptor | 2.7.10.1 | 0.515 | |
| 4qmn | DB8 | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.514 | |
| 2of4 | 979 | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.512 | |
| 3vs3 | VSE | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.512 | |
| 3a4o | STU | Tyrosine-protein kinase Lyn | 2.7.10.2 | 0.511 | |
| 3uvq | FS8 | Mitogen-activated protein kinase 14 | / | 0.511 | |
| 4i22 | IRE | Epidermal growth factor receptor | 2.7.10.1 | 0.511 | |
| 2h8h | H8H | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.510 | |
| 2qo9 | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.510 | |
| 2xp2 | VGH | ALK tyrosine kinase receptor | 2.7.10.1 | 0.509 | |
| 3ue4 | DB8 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.507 | |
| 3ad6 | KSC | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.506 | |
| 3v8w | 0G2 | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.506 | |
| 4o0r | X4Z | Serine/threonine-protein kinase PAK 1 | 2.7.11.1 | 0.506 | |
| 4k11 | 0J9 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.505 | |
| 2zv9 | PP2 | Tyrosine-protein kinase Lyn | 2.7.10.2 | 0.504 | |
| 2xyu | Q9G | Ephrin type-A receptor 4 | 2.7.10.1 | 0.503 | |
| 3b8r | 887 | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.502 | |
| 4gk3 | L87 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.502 | |
| 4xli | 1N1 | Abelson tyrosine-protein kinase 2 | 2.7.10.2 | 0.502 | |
| 1qpd | STU | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.501 | |
| 2fgi | PD1 | Fibroblast growth factor receptor 1 | / | 0.501 | |
| 4bid | IE8 | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.501 | |
| 4j97 | ACP | Fibroblast growth factor receptor 2 | / | 0.501 | |
| 1qpe | PP2 | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.500 | |
| 2itz | IRE | Epidermal growth factor receptor | 2.7.10.1 | 0.500 | |
| 4jia | 1K3 | Tyrosine-protein kinase JAK2 | / | 0.500 | |
| 4jrv | KJV | Epidermal growth factor receptor | 2.7.10.1 | 0.500 | |
| 5aaa | VGH | ALK tyrosine kinase receptor | 2.7.10.1 | 0.500 | |
| 2i0e | PDS | Protein kinase C beta type | 2.7.11.13 | 0.499 | |
| 3ac3 | KSH | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.499 | |
| 4i23 | 1C9 | Epidermal growth factor receptor | 2.7.10.1 | 0.499 | |
| 1sm2 | STU | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.498 | |
| 3vs5 | VSG | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.498 | |
| 3l8p | 0CE | Angiopoietin-1 receptor | 2.7.10.1 | 0.497 | |
| 3vjo | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.497 | |
| 2ivu | ZD6 | Proto-oncogene tyrosine-protein kinase receptor Ret | 2.7.10.1 | 0.496 | |
| 4gmy | 0X5 | Tyrosine-protein kinase JAK2 | / | 0.496 | |
| 2zva | 1N1 | Tyrosine-protein kinase Lyn | 2.7.10.2 | 0.495 | |
| 2y6o | 1N1 | Ephrin type-A receptor 4 | 2.7.10.1 | 0.494 | |
| 4ic7 | ANP | Mitogen-activated protein kinase 7 | 2.7.11.24 | 0.494 | |
| 4mcv | 29K | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.494 | |
| 4nk9 | 2K5 | Fibroblast growth factor receptor 1 | / | 0.494 | |
| 4qmx | H8H | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.494 | |
| 4wkq | IRE | Epidermal growth factor receptor | 2.7.10.1 | 0.494 | |
| 2bdj | HET | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.493 | |
| 2zm4 | KSM | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.493 | |
| 3vs1 | VSA | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.493 | |
| 4lgg | VGG | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.493 | |
| 2p2h | 994 | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.492 | |
| 2vrx | 447 | Aurora kinase B-A | 2.7.11.1 | 0.492 | |
| 3ac2 | KSE | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.492 | |
| 1m17 | AQ4 | Epidermal growth factor receptor | 2.7.10.1 | 0.491 | |
| 5hes | 032 | Mitogen-activated protein kinase kinase kinase 20 | 2.7.11.25 | 0.491 | |
| 2vx0 | 7X7 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.490 | |
| 2yfx | VGH | ALK tyrosine kinase receptor | 2.7.10.1 | 0.490 | |
| 3vs0 | VS0 | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.490 | |
| 1y57 | MPZ | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.488 | |
| 3ac5 | KZM | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.485 | |
| 3vs2 | VSB | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.485 | |
| 4btk | DTQ | Tau-tubulin kinase 1 | 2.7.11.1 | 0.485 | |
| 2bdf | 24A | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.484 | |
| 2zyb | KSL | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.484 | |
| 4fic | 0UL | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.484 | |
| 2vd5 | BI8 | Myotonin-protein kinase | 2.7.11.1 | 0.482 | |
| 3vs4 | VSF | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.482 | |
| 2pzp | ACP | Fibroblast growth factor receptor 2 | / | 0.481 | |
| 3a7h | ATP | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.481 | |
| 3ac1 | KZI | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.481 | |
| 4c62 | XWW | Tyrosine-protein kinase JAK2 | / | 0.481 | |
| 3f5p | 741 | Insulin-like growth factor 1 receptor | 2.7.10.1 | 0.480 | |
| 3vry | B43 | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.480 | |
| 4c3f | 7KW | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.480 | |
| 2gcd | STU | Serine/threonine-protein kinase TAO2 | 2.7.11.1 | 0.479 | |
| 2j0k | 4ST | Focal adhesion kinase 1 | 2.7.10.2 | 0.479 | |
| 2v7a | 627 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.479 | |
| 2vwy | 7X5 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.479 | |
| 2w0j | ZAT | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.478 | |
| 4c4h | 7RO | Dual specificity protein kinase TTK | 2.7.12.1 | 0.478 | |
| 4ks8 | B49 | Serine/threonine-protein kinase PAK 6 | 2.7.11.1 | 0.478 | |
| 2dq7 | STU | Tyrosine-protein kinase Fyn | 2.7.10.2 | 0.477 | |
| 4ans | VGH | ALK tyrosine kinase receptor | 2.7.10.1 | 0.477 | |
| 4dfl | 0K0 | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.477 | |
| 2vx1 | 7X8 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.476 | |
| 2ycr | HCW | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.476 | |
| 4anq | VGH | ALK tyrosine kinase receptor | 2.7.10.1 | 0.476 | |
| 4bb4 | 32W | Ephrin type-B receptor 4 | 2.7.10.1 | 0.476 | |
| 5d12 | G97 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.476 | |
| 2vwu | 7X1 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.475 | |
| 5ajq | DB8 | Serine/threonine-protein kinase 10 | 2.7.11.1 | 0.475 | |
| 2eb3 | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.474 | |
| 2py3 | ACP | Fibroblast growth factor receptor 2 | / | 0.474 | |
| 3u4u | LNH | Casein kinase II subunit alpha | 2.7.11.1 | 0.474 | |
| 3zew | STU | Ephrin type-B receptor 4 | 2.7.10.1 | 0.474 | |
| 1ad5 | ANP | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.473 | |
| 1szm | BI4 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.473 | |
| 4g2f | C07 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.473 | |
| 1byg | STU | Tyrosine-protein kinase CSK | / | 0.472 | |
| 1vjy | 460 | TGF-beta receptor type-1 | 2.7.11.30 | 0.472 | |
| 2qoc | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.472 | |
| 2x9f | X9F | Ephrin type-B receptor 4 | 2.7.10.1 | 0.472 | |
| 4jbo | WPH | Aurora kinase A | 2.7.11.1 | 0.472 | |
| 3amb | VX6 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.471 | |
| 4flh | 14K | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.471 | |
| 4fsq | HK3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.471 | |
| 4xey | 1N1 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.471 | |
| 4yzc | STU | Serine/threonine-protein kinase/endoribonuclease IRE1 | 2.7.11.1 | 0.471 | |
| 2itp | AEE | Epidermal growth factor receptor | 2.7.10.1 | 0.470 | |
| 2itq | ITQ | Epidermal growth factor receptor | 2.7.10.1 | 0.470 | |
| 2pz5 | ACP | Fibroblast growth factor receptor 2 | / | 0.470 | |
| 2q0b | ACP | Fibroblast growth factor receptor 2 | / | 0.470 | |
| 2vww | 7X2 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.470 | |
| 2x2l | X2L | Proto-oncogene tyrosine-protein kinase receptor Ret | 2.7.10.1 | 0.470 | |
| 4fob | 0US | ALK tyrosine kinase receptor | 2.7.10.1 | 0.470 | |
| 4k33 | ACP | Fibroblast growth factor receptor 3 | 2.7.10.1 | 0.470 | |
| 2itt | AEE | Epidermal growth factor receptor | 2.7.10.1 | 0.469 | |
| 2j0j | 4ST | Focal adhesion kinase 1 | 2.7.10.2 | 0.469 | |
| 4fr4 | STU | Serine/threonine-protein kinase 32A | 2.7.11.1 | 0.469 | |
| 3f69 | XDR | Serine/threonine-protein kinase PknB | 2.7.11.1 | 0.468 | |
| 3w33 | W19 | Epidermal growth factor receptor | 2.7.10.1 | 0.468 | |
| 4bib | IEO | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.468 | |
| 5e8x | STU | TGF-beta receptor type-1 | 2.7.11.30 | 0.468 | |
| 2vwx | 7X4 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.467 | |
| 3acj | KSS | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.467 | |
| 3cok | ANP | Serine/threonine-protein kinase PLK4 | 2.7.11.21 | 0.467 | |
| 3js2 | VM1 | Fibroblast growth factor receptor 1 | / | 0.467 | |
| 4jq8 | KJ8 | Epidermal growth factor receptor | 2.7.10.1 | 0.467 | |
| 4bch | T7Z | Cyclin-dependent kinase 9 | 2.7.11.22 | 0.466 | |
| 4grb | 0XG | Casein kinase II subunit alpha | 2.7.11.1 | 0.466 | |
| 4hvh | 19R | Tyrosine-protein kinase JAK3 | 2.7.10.2 | 0.466 | |
| 5aac | VGH | ALK tyrosine kinase receptor | 2.7.10.1 | 0.466 | |
| 1jpa | ANP | Ephrin type-B receptor 2 | 2.7.10.1 | 0.465 | |
| 2qoq | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.465 | |
| 4fst | HK4 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.465 | |
| 4hvi | 19S | Tyrosine-protein kinase JAK3 | 2.7.10.2 | 0.465 | |
| 1ie4 | T44 | Transthyretin | / | 0.464 | |
| 2itn | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.464 | |
| 4c4g | 7RO | Dual specificity protein kinase TTK | 2.7.12.1 | 0.464 | |
| 4u97 | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.464 | |
| 1xkk | FMM | Epidermal growth factor receptor | 2.7.10.1 | 0.463 | |
| 1zyj | BI5 | Mitogen-activated protein kinase 14 | / | 0.463 | |
| 2f2c | AP9 | Cyclin-dependent kinase 6 | 2.7.11.22 | 0.463 | |
| 2pzr | ACP | Fibroblast growth factor receptor 2 | / | 0.463 | |
| 4eym | 0RX | Mitogen-activated protein kinase 13 | 2.7.11.24 | 0.463 | |
| 4ftt | 6HK | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.463 | |
| 4jbq | VX6 | Aurora kinase A | 2.7.11.1 | 0.463 | |
| 4qms | 1N1 | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.463 | |
| 5ap5 | 7RO | Dual specificity protein kinase TTK | 2.7.12.1 | 0.463 | |
| 1uvr | BI8 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.462 | |
| 3bbt | FMM | Receptor tyrosine-protein kinase erbB-4 | 2.7.10.1 | 0.462 | |
| 4f63 | 0S7 | Fibroblast growth factor receptor 1 | / | 0.462 | |
| 4hvg | 19Q | Tyrosine-protein kinase JAK3 | 2.7.10.2 | 0.462 | |
| 5bvw | 1N1 | Epithelial discoidin domain-containing receptor 1 | 2.7.10.1 | 0.462 | |
| 2etm | 7PY | Focal adhesion kinase 1 | 2.7.10.2 | 0.461 | |
| 2vwz | 7X6 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.461 | |
| 3be9 | P04 | Casein kinase II subunit alpha | 2.7.11.1 | 0.461 | |
| 3gc9 | B45 | Mitogen-activated protein kinase 11 | 2.7.11.24 | 0.461 | |
| 3r9d | X6B | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.461 | |
| 4bf2 | STU | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.461 | |
| 4yuq | KS1 | Calmodulin-like domain protein kinase | / | 0.461 | |
| 2itw | ITQ | Epidermal growth factor receptor | 2.7.10.1 | 0.460 | |
| 2j0l | ANP | Focal adhesion kinase 1 | 2.7.10.2 | 0.460 | |
| 3oom | 507 | Activin receptor type-1 | 2.7.11.30 | 0.460 | |
| 4c4i | X20 | Dual specificity protein kinase TTK | 2.7.12.1 | 0.460 | |
| 5amn | DTQ | Proto-oncogene tyrosine-protein kinase receptor Ret | 2.7.10.1 | 0.460 | |
| 5e8w | STU | TGF-beta receptor type-1 | 2.7.11.30 | 0.460 | |
| 1qcf | PP1 | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.459 | |
| 2j0m | 4ST | Focal adhesion kinase 1 | 2.7.10.2 | 0.459 | |
| 4fz6 | 0VG | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.459 | |
| 4qml | ANP | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.459 | |
| 2hog | 710 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.458 | |
| 2pvy | ACP | Fibroblast growth factor receptor 2 | / | 0.458 | |
| 2xyn | VX6 | Abelson tyrosine-protein kinase 2 | 2.7.10.2 | 0.458 | |
| 3at4 | CCK | Casein kinase II subunit alpha | 2.7.11.1 | 0.458 | |
| 3gub | GUB | Death-associated protein kinase 1 | 2.7.11.1 | 0.458 | |
| 4c4f | 7CE | Dual specificity protein kinase TTK | 2.7.12.1 | 0.458 | |
| 4jq7 | KJQ | Epidermal growth factor receptor | 2.7.10.1 | 0.458 | |
| 2wou | ZZF | TGF-beta receptor type-1 | 2.7.11.30 | 0.457 | |
| 2yit | YIT | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.457 | |
| 3e5a | VX6 | Aurora kinase A | 2.7.11.1 | 0.457 | |
| 3lj3 | WYE | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.457 | |
| 1fin | ATP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.456 | |
| 3d7t | STU | Tyrosine-protein kinase CSK | / | 0.456 | |
| 3mtf | A3F | Activin receptor type-1 | 2.7.11.30 | 0.456 | |
| 3wow | ANP | Casein kinase II subunit alpha | 2.7.11.1 | 0.456 | |
| 4i0r | 1B4 | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.456 | |
| 4j98 | ACP | Fibroblast growth factor receptor 2 | / | 0.456 | |
| 1e90 | MYC | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.455 | |
| 2xk9 | XK9 | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.455 | |
| 3c7q | XIN | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.455 | |
| 3ncg | BK1 | Calmodulin-domain protein kinase 1, putative | / | 0.455 | |
| 4b8m | VX6 | Aurora kinase B-A | 2.7.11.1 | 0.455 | |
| 4nky | 3QZ | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.455 | |
| 2f4j | VX6 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.454 | |
| 2o0u | C0M | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.454 | |
| 2xa4 | AZ5 | Tyrosine-protein kinase JAK2 | / | 0.454 | |
| 3beg | ANP | SRSF protein kinase 1 | 2.7.11.1 | 0.454 | |
| 3orz | BI4 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.454 | |
| 4bdb | ODO | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.454 | |
| 5l8l | ADP | Aurora kinase A | 2.7.11.1 | 0.454 | |
| 1di8 | DTQ | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.453 | |
| 2hxl | 422 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.453 | |
| 2r7b | 253 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.453 | |
| 2wot | ZZG | TGF-beta receptor type-1 | 2.7.11.30 | 0.453 | |
| 3hx4 | ANP | Calmodulin-domain protein kinase 1 | / | 0.453 | |
| 1oiy | N41 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.452 | |
| 2ijm | ADP | Focal adhesion kinase 1 | 2.7.10.2 | 0.452 | |
| 2w05 | FRT | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.452 | |
| 2ycq | UPX | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.452 | |
| 3lcd | BDY | Macrophage colony-stimulating factor 1 receptor | 2.7.10.1 | 0.452 | |
| 3say | OFT | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.452 | |
| 2ivv | PP1 | Proto-oncogene tyrosine-protein kinase receptor Ret | 2.7.10.1 | 0.451 | |
| 2r0u | M54 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.451 | |
| 2vu3 | LZE | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.451 | |
| 2y00 | Y01 | Beta-1 adrenergic receptor | / | 0.451 | |
| 3q4z | ANP | Serine/threonine-protein kinase PAK 1 | 2.7.11.1 | 0.451 | |
| 4f65 | 0S9 | Fibroblast growth factor receptor 1 | / | 0.451 | |
| 4ieb | ANP | Calmodulin-domain protein kinase 1 | / | 0.451 | |
| 2c0o | L2G | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.450 | |
| 2e9n | 76A | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.450 | |
| 2xik | J60 | Serine/threonine-protein kinase 25 | 2.7.11.1 | 0.450 | |
| 4ccu | AWF | ALK tyrosine kinase receptor | 2.7.10.1 | 0.450 | |
| 4ftk | H9K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.450 | |
| 5ar4 | SB2 | Receptor-interacting serine/threonine-protein kinase 2 | 2.7.11.1 | 0.450 | |
| 1q41 | IXM | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.449 | |
| 1yvj | 4ST | Tyrosine-protein kinase JAK3 | 2.7.10.2 | 0.449 | |
| 3fls | FLS | Mitogen-activated protein kinase 14 | / | 0.449 | |
| 3qk0 | QK0 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.449 | |
| 3sgx | 0FW | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.449 | |
| 3tmz | 06X | Cytochrome P450 2B4 | 1.14.14.1 | 0.449 | |
| 3tuc | FPW | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.449 | |
| 4acc | 7YG | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.449 | |
| 4ftm | 1HK | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.449 | |
| 4fux | E75 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.449 | |
| 4fyn | 0VE | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.449 | |
| 4ia2 | BIV | Vitamin D3 receptor A | / | 0.449 | |
| 4jbp | YPH | Aurora kinase A | 2.7.11.1 | 0.449 | |
| 4jr3 | KJR | Epidermal growth factor receptor | 2.7.10.1 | 0.449 | |
| 1a72 | PAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.448 | |
| 2yn8 | STU | Ephrin type-B receptor 4 | 2.7.10.1 | 0.448 | |
| 3a62 | STU | Ribosomal protein S6 kinase beta-1 | 2.7.11.1 | 0.448 | |
| 3ml8 | ML8 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.448 | |
| 3s4q | NK0 | Mitogen-activated protein kinase 14 | / | 0.448 | |
| 4bbf | O19 | Tyrosine-protein kinase JAK2 | / | 0.448 | |
| 4c34 | STU | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.448 | |
| 4eqc | XR1 | Serine/threonine-protein kinase PAK 1 | 2.7.11.1 | 0.448 | |
| 4f9w | LM4 | Mitogen-activated protein kinase 14 | / | 0.448 | |
| 4fv9 | E71 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.448 | |
| 4hjo | AQ4 | Epidermal growth factor receptor | 2.7.10.1 | 0.448 | |
| 4j6d | TES | Cytochrome P450 monooxygenase | / | 0.448 | |
| 4xhg | ADP | Uncharacterized protein | / | 0.448 | |
| 1ee0 | CAA | 2-pyrone synthase | / | 0.447 | |
| 2xm9 | LWH | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.447 | |
| 3l08 | ZIG | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.447 | |
| 3w18 | N13 | Aurora kinase A | 2.7.11.1 | 0.447 | |
| 4cd0 | AWJ | ALK tyrosine kinase receptor | 2.7.10.1 | 0.447 | |
| 4ftn | 2HK | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.447 | |
| 4qmt | H1N | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.447 | |
| 2jed | LG8 | Protein kinase C theta type | 2.7.11.13 | 0.446 | |
| 3fln | 3FN | Mitogen-activated protein kinase 14 | / | 0.446 | |
| 3icr | COA | Coenzyme A disulfide reductase | / | 0.446 | |
| 4hyu | 1BK | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.446 | |
| 4j6c | STR | Cytochrome P450 monooxygenase | / | 0.446 | |
| 4riy | ADP | Epidermal growth factor receptor | 2.7.10.1 | 0.446 | |
| 2hen | ADP | Ephrin type-B receptor 2 | 2.7.10.1 | 0.445 | |
| 3sd0 | TSK | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.445 | |
| 3t14 | FAD | Sulfide-quinone reductase | / | 0.445 | |
| 4gt3 | ATP | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.445 | |
| 1u59 | STU | Tyrosine-protein kinase ZAP-70 | 2.7.10.2 | 0.444 | |
| 3e9y | FAB | Acetolactate synthase, chloroplastic | 2.2.1.6 | 0.444 | |
| 3fzp | AGS | Protein-tyrosine kinase 2-beta | 2.7.10.2 | 0.444 | |
| 3tti | KBI | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.444 | |
| 3uvp | 048 | Mitogen-activated protein kinase 14 | / | 0.444 | |
| 3w0s | ANP | Hygromycin-B 4-O-kinase | 2.7.1.163 | 0.444 | |
| 4b99 | R4L | Mitogen-activated protein kinase 7 | 2.7.11.24 | 0.444 | |
| 4bcq | TJF | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.444 | |
| 1oec | AA2 | Fibroblast growth factor receptor 2 | / | 0.443 | |
| 2c7x | NRB | Cytochrome P450 monooxygenase PikC | / | 0.443 | |
| 2wle | COA | Polysialic acid O-acetyltransferase | / | 0.443 | |
| 2yir | YIR | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.443 | |
| 2zjw | REF | Casein kinase II subunit alpha | 2.7.11.1 | 0.443 | |
| 3erk | SB4 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.443 | |
| 4d0l | 093 | Phosphatidylinositol 4-kinase beta | 2.7.1.67 | 0.443 | |
| 4dk5 | 0KO | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.443 | |
| 4lgh | 0JN | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.443 | |
| 5aab | VGH | ALK tyrosine kinase receptor | 2.7.10.1 | 0.443 | |
| 1c1d | NAI | Phenylalanine dehydrogenase | / | 0.442 | |
| 1rfv | ADP | Pyridoxal kinase | 2.7.1.35 | 0.442 | |
| 2i40 | BLZ | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.442 | |
| 2yiq | YIQ | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.442 | |
| 3t2z | FAD | Sulfide-quinone reductase | / | 0.442 | |
| 3ttj | JBI | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.442 | |
| 4dfn | 0K1 | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.442 | |
| 4ftl | H0K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.442 | |
| 4otw | DB8 | Receptor tyrosine-protein kinase erbB-3 | 2.7.10.1 | 0.442 | |
| 1fm4 | DXC | Major pollen allergen Bet v 1-L | / | 0.441 | |
| 1wvx | BD4 | Death-associated protein kinase 1 | 2.7.11.1 | 0.441 | |
| 2brm | DFZ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.441 | |
| 2fvd | LIA | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.441 | |
| 2izs | BRQ | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.441 | |
| 2y02 | Y01 | Beta-1 adrenergic receptor | / | 0.441 | |
| 3c4x | ATP | Rhodopsin kinase | / | 0.441 | |
| 3eb0 | DRK | Uncharacterized protein | / | 0.441 | |
| 3poz | 03P | Epidermal growth factor receptor | 2.7.10.1 | 0.441 | |
| 3u9n | 09H | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.441 | |
| 3vjn | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.441 | |
| 1bvr | THT | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.440 | |
| 1pjk | ANP | Casein kinase II subunit alpha | 2.7.11.1 | 0.440 | |
| 1rw8 | 580 | TGF-beta receptor type-1 | 2.7.11.30 | 0.440 | |
| 2bfy | H1N | Aurora kinase B-A | 2.7.11.1 | 0.440 | |
| 2y46 | MIV | Mycinamicin IV hydroxylase/epoxidase | / | 0.440 | |
| 3cd3 | STU | Tyrosine-protein kinase Fes/Fps | 2.7.10.2 | 0.440 | |
| 3lpb | NVB | Tyrosine-protein kinase JAK2 | / | 0.440 | |
| 4beb | ATP | Type I restriction enzyme EcoR124II R protein | 3.1.21.3 | 0.440 | |
| 4fsu | HK5 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.440 | |
| 4kba | 1QM | Casein kinase I isoform delta | 2.7.11.1 | 0.440 | |
| 4wsq | KSA | AP2-associated protein kinase 1 | 2.7.11.1 | 0.440 |