sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4l42 | 5FI | Ribosomal protein S6 kinase beta-1 | 2.7.11.1 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 4l42 | 5FI | Ribosomal protein S6 kinase beta-1 | 2.7.11.1 | 1.000 | |
| 4l3j | 5FI | Ribosomal protein S6 kinase beta-1 | 2.7.11.1 | 0.608 | |
| 3we4 | 5FI | Ribosomal protein S6 kinase beta-1 | 2.7.11.1 | 0.603 | |
| 4l3l | 5FI | Ribosomal protein S6 kinase beta-1 | 2.7.11.1 | 0.588 | |
| 2hog | 710 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.517 | |
| 4ftt | 6HK | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.515 | |
| 1uu8 | BI1 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.510 | |
| 3amb | VX6 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.508 | |
| 4fti | H7K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.497 | |
| 2xck | MH4 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.496 | |
| 4l45 | 5FI | Ribosomal protein S6 kinase beta-1 | 2.7.11.1 | 0.495 | |
| 4k1b | 1OC | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.494 | |
| 1uu3 | LY4 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.493 | |
| 1uvr | BI8 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.491 | |
| 1zrz | BI1 | Protein kinase C iota type | 2.7.11.13 | 0.490 | |
| 3zh8 | C58 | Protein kinase C iota type | 2.7.11.13 | 0.489 | |
| 4fr4 | STU | Serine/threonine-protein kinase 32A | 2.7.11.1 | 0.487 | |
| 3lij | ANP | Calcium/calmodulin dependent protein kinase with a kinase domain and 4 calmodulin like EF hands | / | 0.486 | |
| 4xx9 | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.485 | |
| 3rwp | ABQ | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.484 | |
| 2r7b | 253 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.483 | |
| 3a99 | ANP | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.482 | |
| 3a7h | ATP | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.481 | |
| 1uu7 | BI2 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.479 | |
| 1yvj | 4ST | Tyrosine-protein kinase JAK3 | 2.7.10.2 | 0.479 | |
| 2hy8 | 1ST | Serine/threonine-protein kinase PAK 1 | 2.7.11.1 | 0.479 | |
| 4enx | Z20 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.479 | |
| 1uu9 | BI3 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.478 | |
| 3tkh | 07S | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.476 | |
| 3v8w | 0G2 | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.476 | |
| 4l44 | 5FI | Ribosomal protein S6 kinase beta-1 | 2.7.11.1 | 0.476 | |
| 4rqv | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.476 | |
| 1wvx | BD4 | Death-associated protein kinase 1 | 2.7.11.1 | 0.475 | |
| 4gmy | 0X5 | Tyrosine-protein kinase JAK2 | / | 0.475 | |
| 1okz | UCN | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.473 | |
| 3t14 | FAD | Sulfide-quinone reductase | / | 0.473 | |
| 4eut | BX7 | Serine/threonine-protein kinase TBK1 | 2.7.11.1 | 0.472 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.470 | |
| 1uuo | BRF | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.470 | |
| 2cgw | 3C3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.470 | |
| 1k6p | XN3 | Gag-Pol polyprotein | 3.4.23.16 | 0.469 | |
| 2pe1 | 517 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.469 | |
| 2vd5 | BI8 | Myotonin-protein kinase | 2.7.11.1 | 0.469 | |
| 4k18 | 1OB | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.469 | |
| 2h8h | H8H | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.468 | |
| 2hy0 | 306 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.467 | |
| 3vt9 | YI4 | Vitamin D3 receptor | / | 0.467 | |
| 2b00 | GCH | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.466 | |
| 2c7x | NRB | Cytochrome P450 monooxygenase PikC | / | 0.466 | |
| 2obj | VRV | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.466 | |
| 3iok | 1P6 | Tyrosine-protein kinase JAK2 | / | 0.466 | |
| 3lcd | BDY | Macrophage colony-stimulating factor 1 receptor | 2.7.10.1 | 0.466 | |
| 4c4f | 7CE | Dual specificity protein kinase TTK | 2.7.12.1 | 0.466 | |
| 4c4g | 7RO | Dual specificity protein kinase TTK | 2.7.12.1 | 0.466 | |
| 4c62 | XWW | Tyrosine-protein kinase JAK2 | / | 0.466 | |
| 4riy | ADP | Epidermal growth factor receptor | 2.7.10.1 | 0.466 | |
| 1xr1 | ANP | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.465 | |
| 2bdf | 24A | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.465 | |
| 2xf0 | 4UB | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.465 | |
| 4fv9 | E71 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.465 | |
| 4aw3 | MYV | Mycinamicin IV hydroxylase/epoxidase | / | 0.464 | |
| 5ack | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.464 | |
| 3at4 | CCK | Casein kinase II subunit alpha | 2.7.11.1 | 0.463 | |
| 4bbe | 3O4 | Tyrosine-protein kinase JAK2 | / | 0.463 | |
| 4kik | KSA | Inhibitor of nuclear factor kappa-B kinase subunit beta | 2.7.11.10 | 0.463 | |
| 2nru | T12 | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.462 | |
| 2ydi | YDI | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.462 | |
| 3ma3 | 01I | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.462 | |
| 3r04 | UNQ | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.462 | |
| 3t2z | FAD | Sulfide-quinone reductase | / | 0.462 | |
| 4a06 | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.462 | |
| 4i22 | IRE | Epidermal growth factor receptor | 2.7.10.1 | 0.462 | |
| 4kzo | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.462 | |
| 4l7s | G7K | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.462 | |
| 1qpj | STU | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.461 | |
| 2j7t | 274 | Serine/threonine-protein kinase 10 | 2.7.11.1 | 0.461 | |
| 3opd | HIE | Heat shock protein 83 | / | 0.461 | |
| 4fuy | EK2 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.461 | |
| 1xkd | NAP | Isocitrate dehydrogenase [NADP] | / | 0.460 | |
| 2xbj | XBJ | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.460 | |
| 3dey | DHT | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.460 | |
| 3klm | DHT | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.460 | |
| 3t2y | FAD | Sulfide-quinone reductase | / | 0.460 | |
| 3v5l | 0G1 | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.460 | |
| 4hge | 15V | Tyrosine-protein kinase JAK2 | / | 0.460 | |
| 4ji9 | 1M3 | Tyrosine-protein kinase JAK2 | / | 0.460 | |
| 4l43 | 5FI | Ribosomal protein S6 kinase beta-1 | 2.7.11.1 | 0.460 | |
| 4oa9 | ANP | Protein BRASSINOSTEROID INSENSITIVE 1 | 2.7.10.1 | 0.460 | |
| 3nun | JMZ | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.459 | |
| 2ayp | 43A | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.458 | |
| 2x6d | X6D | Aurora kinase A | 2.7.11.1 | 0.458 | |
| 3cyl | VIT | Basic phospholipase A2 homolog piratoxin-2 | / | 0.458 | |
| 3qd3 | 3Q5 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.457 | |
| 3rak | 03Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.457 | |
| 4ez5 | 0RS | Cyclin-dependent kinase 6 | 2.7.11.22 | 0.457 | |
| 4izy | 1J2 | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.457 | |
| 5dt0 | SKE | Aurora kinase A | 2.7.11.1 | 0.457 | |
| 2znn | S44 | Peroxisome proliferator-activated receptor alpha | / | 0.456 | |
| 3orz | BI4 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.456 | |
| 3zep | 1NX | Tyrosine-protein kinase JAK3 | 2.7.10.2 | 0.456 | |
| 4bbf | O19 | Tyrosine-protein kinase JAK2 | / | 0.456 | |
| 4o0r | X4Z | Serine/threonine-protein kinase PAK 1 | 2.7.11.1 | 0.456 | |
| 2c3l | IDZ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.455 | |
| 3a4o | STU | Tyrosine-protein kinase Lyn | 2.7.10.2 | 0.455 | |
| 3bqr | 4RB | Death-associated protein kinase 3 | / | 0.455 | |
| 3q9x | EMO | Casein kinase II subunit alpha | 2.7.11.1 | 0.455 | |
| 3sz0 | FAD | Sulfide-quinone reductase | / | 0.455 | |
| 4flh | 14K | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.455 | |
| 4fsr | HKC | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.455 | |
| 2pyw | ADP | Methylthioribose kinase | 2.7.1.100 | 0.454 | |
| 2w1f | L0F | Aurora kinase A | 2.7.11.1 | 0.454 | |
| 3a62 | STU | Ribosomal protein S6 kinase beta-1 | 2.7.11.1 | 0.454 | |
| 3inm | NDP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.454 | |
| 3ofm | 4B0 | Casein kinase II subunit alpha' | 2.7.11.1 | 0.454 | |
| 3tmz | 06X | Cytochrome P450 2B4 | 1.14.14.1 | 0.454 | |
| 3vt8 | YI3 | Vitamin D3 receptor | / | 0.454 | |
| 4cd0 | AWJ | ALK tyrosine kinase receptor | 2.7.10.1 | 0.454 | |
| 4dit | 0KD | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.454 | |
| 4rup | H97 | Vitamin D3 receptor A | / | 0.454 | |
| 4y8w | STR | Steroid 21-hydroxylase | / | 0.454 | |
| 1h66 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.453 | |
| 1xl2 | 189 | Gag-Pol polyprotein | 3.4.23.16 | 0.453 | |
| 2izr | BRK | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.453 | |
| 2vv9 | IM9 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.453 | |
| 3ggf | GVD | Serine/threonine-protein kinase 26 | / | 0.453 | |
| 3zk5 | Z18 | Cytochrome P450 monooxygenase PikC | / | 0.453 | |
| 4jay | FAD | UDP-N-acetylenolpyruvoylglucosamine reductase | / | 0.453 | |
| 1h69 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.452 | |
| 1pjk | ANP | Casein kinase II subunit alpha | 2.7.11.1 | 0.452 | |
| 1q3w | ATU | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.452 | |
| 1yol | S03 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.452 | |
| 4c34 | STU | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.452 | |
| 4f64 | 0S8 | Fibroblast growth factor receptor 1 | / | 0.452 | |
| 3bkb | STU | Tyrosine-protein kinase Fes/Fps | 2.7.10.2 | 0.451 | |
| 3fzp | AGS | Protein-tyrosine kinase 2-beta | 2.7.10.2 | 0.451 | |
| 3v5j | 0F2 | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.451 | |
| 4ia2 | BIV | Vitamin D3 receptor A | / | 0.451 | |
| 1ie4 | T44 | Transthyretin | / | 0.450 | |
| 1j1c | ADP | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.450 | |
| 2r0u | M54 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.450 | |
| 2ycq | UPX | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.450 | |
| 2yir | YIR | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.450 | |
| 3bhe | BZN | Gag-Pol polyprotein | 3.4.23.16 | 0.450 | |
| 3ckx | STU | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.450 | |
| 3l08 | ZIG | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.450 | |
| 3l8p | 0CE | Angiopoietin-1 receptor | 2.7.10.1 | 0.450 | |
| 3sw7 | 19K | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.450 | |
| 4acm | 7YG | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.450 | |
| 4c58 | 824 | Cyclin-G-associated kinase | 2.7.11.1 | 0.450 | |
| 4feq | 0T8 | Tyrosine-protein kinase receptor TYRO3 | 2.7.10.1 | 0.450 | |
| 4ia7 | BIV | Vitamin D3 receptor A | / | 0.450 | |
| 4ivb | 1J5 | Tyrosine-protein kinase JAK1 | / | 0.450 | |
| 4u97 | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.450 | |
| 3sn6 | P0G | Beta-2 adrenergic receptor | / | 0.450 | |
| 1k6t | XN1 | Gag-Pol polyprotein | 3.4.23.16 | 0.449 | |
| 1k6v | XN2 | Gag-Pol polyprotein | 3.4.23.16 | 0.449 | |
| 2i4j | DRJ | Peroxisome proliferator-activated receptor gamma | / | 0.449 | |
| 3be9 | P04 | Casein kinase II subunit alpha | 2.7.11.1 | 0.449 | |
| 3i4b | Z48 | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.449 | |
| 3nwx | KVS | Gag-Pol polyprotein | 3.4.23.16 | 0.449 | |
| 3oez | STI | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.449 | |
| 3qtz | X42 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.449 | |
| 3v9v | 21L | Peroxisome proliferator-activated receptor gamma | / | 0.449 | |
| 4ewn | 0VR | Imidazole glycerol phosphate synthase subunit HisF | 4.1.3 | 0.449 | |
| 4ft0 | HK9 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.449 | |
| 4u9a | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.449 | |
| 1fin | ATP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.448 | |
| 1zeo | C01 | Peroxisome proliferator-activated receptor gamma | / | 0.448 | |
| 2azz | TCH | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.448 | |
| 2xc3 | RT8 | Steroid C26-monooxygenase | 1.14.13.141 | 0.448 | |
| 2y98 | MIV | Mycinamicin IV hydroxylase/epoxidase | / | 0.448 | |
| 4c4h | 7RO | Dual specificity protein kinase TTK | 2.7.12.1 | 0.448 | |
| 4dk5 | 0KO | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.448 | |
| 4fko | 20K | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.448 | |
| 4nky | 3QZ | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.448 | |
| 1pdh | FAS | p-hydroxybenzoate hydroxylase | / | 0.447 | |
| 1qbg | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.447 | |
| 2cmw | OLP | Casein kinase I isoform gamma-1 | 2.7.11.1 | 0.447 | |
| 2j0m | 4ST | Focal adhesion kinase 1 | 2.7.10.2 | 0.447 | |
| 3cbl | STU | Tyrosine-protein kinase Fes/Fps | 2.7.10.2 | 0.447 | |
| 3f69 | XDR | Serine/threonine-protein kinase PknB | 2.7.11.1 | 0.447 | |
| 3t8o | ATP | Rhodopsin kinase | / | 0.447 | |
| 4bf2 | STU | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.447 | |
| 4g17 | 0VN | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.447 | |
| 4gj2 | 0XH | Non-receptor tyrosine-protein kinase TYK2 | 2.7.10.2 | 0.447 | |
| 4i0s | 1B5 | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.447 | |
| 4nxv | GDP | Mitochondrial dynamics protein MID51 | / | 0.447 | |
| 5dqr | FAD | 7-hydroxymethyl chlorophyll a reductase, chloroplastic | 1.17.7.2 | 0.447 | |
| 1pkd | UCN | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.446 | |
| 2i4p | DRH | Peroxisome proliferator-activated receptor gamma | / | 0.446 | |
| 2om9 | AJA | Peroxisome proliferator-activated receptor gamma | / | 0.446 | |
| 2phk | ATP | Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform | 2.7.11.19 | 0.446 | |
| 2w0j | ZAT | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.446 | |
| 2ym7 | YM7 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.446 | |
| 3kpk | FAD | Sulfide-quinone reductase | / | 0.446 | |
| 3syi | FAD | Sulfide-quinone reductase | / | 0.446 | |
| 3vn2 | TLS | Peroxisome proliferator-activated receptor gamma | / | 0.446 | |
| 4l06 | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.446 | |
| 4nka | 2K7 | Fibroblast growth factor receptor 1 | / | 0.446 | |
| 1byg | STU | Tyrosine-protein kinase CSK | / | 0.445 | |
| 1i7i | AZ2 | Peroxisome proliferator-activated receptor gamma | / | 0.445 | |
| 1k6c | MK1 | Gag-Pol polyprotein | 3.4.23.16 | 0.445 | |
| 2cgu | 3A3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.445 | |
| 2hb7 | O1C | Vitamin D3 receptor | / | 0.445 | |
| 2nry | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.445 | |
| 2w05 | FRT | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.445 | |
| 3et7 | 349 | Protein-tyrosine kinase 2-beta | 2.7.10.2 | 0.445 | |
| 4fkv | 61K | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.445 | |
| 4ftr | 5HK | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.445 | |
| 4hvi | 19S | Tyrosine-protein kinase JAK3 | 2.7.10.2 | 0.445 | |
| 4wlo | NAI | Malate dehydrogenase, mitochondrial | 1.1.1.37 | 0.445 | |
| 1ad5 | ANP | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.444 | |
| 1jip | KTN | 6-deoxyerythronolide B hydroxylase | / | 0.444 | |
| 1knu | YPA | Peroxisome proliferator-activated receptor gamma | / | 0.444 | |
| 2iw8 | 4SP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.444 | |
| 2q59 | 240 | Peroxisome proliferator-activated receptor gamma | / | 0.444 | |
| 3gob | HXX | DdmC | / | 0.444 | |
| 3nwq | 2NC | Gag-Pol polyprotein | 3.4.23.16 | 0.444 | |
| 4fhi | 0S4 | Vitamin D3 receptor A | / | 0.444 | |
| 4grb | 0XG | Casein kinase II subunit alpha | 2.7.11.1 | 0.444 | |
| 4iaq | 2GM | 5-hydroxytryptamine receptor 1B | / | 0.444 | |
| 4kbk | 1QG | Casein kinase I isoform delta | 2.7.11.1 | 0.444 | |
| 4mq1 | 2C3 | Dual specificity tyrosine-phosphorylation-regulated kinase 1A | 2.7.12.1 | 0.444 | |
| 5dr6 | SKE | Aurora kinase A | 2.7.11.1 | 0.444 | |
| 5itz | LOC | Tubulin beta-2B chain | / | 0.444 | |
| 1fvv | 107 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.443 | |
| 1jio | DEB | 6-deoxyerythronolide B hydroxylase | / | 0.443 | |
| 1xjd | STU | Protein kinase C theta type | 2.7.11.13 | 0.443 | |
| 2cke | IQU | Death-associated protein kinase 2 | / | 0.443 | |
| 2hc4 | VDX | Vitamin D3 receptor A | / | 0.443 | |
| 2i4z | DRH | Peroxisome proliferator-activated receptor gamma | / | 0.443 | |
| 2qhn | 582 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.443 | |
| 2wmx | ZY6 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.443 | |
| 2y03 | Y01 | Beta-1 adrenergic receptor | / | 0.443 | |
| 2y46 | MIV | Mycinamicin IV hydroxylase/epoxidase | / | 0.443 | |
| 3e8e | G98 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.443 | |
| 3qd4 | 3Q6 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.443 | |
| 3t2k | FAD | Sulfide-quinone reductase | / | 0.443 | |
| 3vsp | EK8 | Peroxisome proliferator-activated receptor gamma | / | 0.443 | |
| 3vt6 | 5YI | Vitamin D3 receptor | / | 0.443 | |
| 3zew | STU | Ephrin type-B receptor 4 | 2.7.10.1 | 0.443 | |
| 4anw | O92 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.443 | |
| 4aqc | 88A | Tyrosine-protein kinase JAK2 | / | 0.443 | |
| 4c4j | X21 | Dual specificity protein kinase TTK | 2.7.12.1 | 0.443 | |
| 4fg7 | ATP | Calcium/calmodulin-dependent protein kinase type 1 | 2.7.11.17 | 0.443 | |
| 4fsn | A58 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.443 | |
| 4g1w | G1W | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.443 | |
| 4mcv | 29K | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.443 | |
| 5dr9 | SKE | Aurora kinase A | 2.7.11.1 | 0.443 | |
| 1kbo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.442 | |
| 2c6h | PXI | Cytochrome P450 monooxygenase PikC | / | 0.442 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.442 | |
| 2h96 | 893 | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.442 | |
| 2nnh | REA | Cytochrome P450 2C8 | / | 0.442 | |
| 2w9s | TOP | Dihydrofolate reductase type 1 from Tn4003 | 1.5.1.3 | 0.442 | |
| 2xch | CKG | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.442 | |
| 3bu5 | ATP | Insulin receptor | 2.7.10.1 | 0.442 | |
| 3oib | FDA | Putative acyl-CoA dehydrogenase | / | 0.442 | |
| 3sgt | P09 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | / | 0.442 | |
| 3w1f | 1O5 | Dual specificity protein kinase TTK | 2.7.12.1 | 0.442 | |
| 4agu | D15 | Cyclin-dependent kinase-like 1 | / | 0.442 | |
| 4ccb | OFG | ALK tyrosine kinase receptor | 2.7.10.1 | 0.442 | |
| 4ezj | 0SC | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.442 | |
| 4gev | CB3 | Thymidylate synthase | / | 0.442 | |
| 4iwo | 1H4 | Serine/threonine-protein kinase TBK1 | 2.7.11.1 | 0.442 | |
| 4j97 | ACP | Fibroblast growth factor receptor 2 | / | 0.442 | |
| 4r21 | STR | Cytochrome P450 family 17 polypeptide 2 | / | 0.442 | |
| 5a4k | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.442 | |
| 1d4a | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.441 | |
| 1oky | STU | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.441 | |
| 2c6e | HPM | Aurora kinase A | 2.7.11.1 | 0.441 | |
| 2fvd | LIA | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.441 | |
| 2ww4 | ADP | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | 2.7.1.148 | 0.441 | |
| 3c0i | 3AM | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.441 | |
| 3t11 | 3T1 | Gag-Pol polyprotein | 3.4.23.16 | 0.441 | |
| 4b7x | NAP | Probable oxidoreductase | / | 0.441 | |
| 4eny | J19 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.441 | |
| 4f4p | 0SB | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.441 | |
| 4ii5 | ADP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.441 | |
| 4wkq | IRE | Epidermal growth factor receptor | 2.7.10.1 | 0.441 | |
| 5br4 | NAD | Lactaldehyde reductase | 1.1.1.77 | 0.441 | |
| 1c70 | L75 | Protease | / | 0.440 | |
| 1s9j | BBM | Dual specificity mitogen-activated protein kinase kinase 1 | 2.7.12.2 | 0.440 | |
| 1zhw | HC2 | Oxysterol-binding protein homolog 4 | / | 0.440 | |
| 2cdz | 23D | Serine/threonine-protein kinase PAK 4 | 2.7.11.1 | 0.440 | |
| 2hxl | 422 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.440 | |
| 2vn0 | TDZ | Cytochrome P450 2C8 | / | 0.440 | |
| 2w06 | FRV | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 | |
| 2ym4 | 4YM | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.440 | |
| 3fco | IIG | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.440 | |
| 3ggg | NAD | Prephenate dehydrogenase | / | 0.440 | |
| 3inx | JZC | Heat shock protein HSP 90-alpha | / | 0.440 | |
| 3o0g | 3O0 | Cyclin-dependent-like kinase 5 | 2.7.11.1 | 0.440 | |
| 3w0a | DS5 | Vitamin D3 receptor | / | 0.440 | |
| 4bcm | T7Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 | |
| 4cy8 | FDA | 2-hydroxybiphenyl-3-monooxygenase | / | 0.440 | |
| 4e4q | RRH | Peroxisome proliferator-activated receptor gamma | / | 0.440 | |
| 4i3z | ADP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 | |
| 4jia | 1K3 | Tyrosine-protein kinase JAK2 | / | 0.440 | |
| 4nb6 | 444 | Nuclear receptor ROR-gamma | / | 0.440 |