Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4i22 | IRE | Epidermal growth factor receptor | 2.7.10.1 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 4i22 | IRE | Epidermal growth factor receptor | 2.7.10.1 | 1.000 | |
| 3vrz | VRZ | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.549 | |
| 2h8h | H8H | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.539 | |
| 4riy | ADP | Epidermal growth factor receptor | 2.7.10.1 | 0.539 | |
| 2c0i | L1G | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.536 | |
| 3vs6 | VSH | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.531 | |
| 3w2s | W2R | Epidermal growth factor receptor | 2.7.10.1 | 0.530 | |
| 3vs4 | VSF | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.529 | |
| 3vs5 | VSG | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.526 | |
| 3vs2 | VSB | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.522 | |
| 1qcf | PP1 | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.521 | |
| 3vs7 | KS1 | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.520 | |
| 3w33 | W19 | Epidermal growth factor receptor | 2.7.10.1 | 0.520 | |
| 4k11 | 0J9 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.519 | |
| 1pmn | 984 | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.514 | |
| 3v8w | 0G2 | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.514 | |
| 3ttj | JBI | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.513 | |
| 3vs1 | VSA | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.510 | |
| 2ycq | UPX | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.508 | |
| 2ycr | HCW | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.508 | |
| 2c0t | L3G | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.507 | |
| 4yuq | KS1 | Calmodulin-like domain protein kinase | / | 0.506 | |
| 3r9d | X6B | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.505 | |
| 4jq8 | KJ8 | Epidermal growth factor receptor | 2.7.10.1 | 0.504 | |
| 3mtf | A3F | Activin receptor type-1 | 2.7.11.30 | 0.502 | |
| 3w32 | W32 | Epidermal growth factor receptor | 2.7.10.1 | 0.502 | |
| 2wot | ZZG | TGF-beta receptor type-1 | 2.7.11.30 | 0.501 | |
| 4k0y | 1OA | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.501 | |
| 4kba | 1QM | Casein kinase I isoform delta | 2.7.11.1 | 0.501 | |
| 2xk9 | XK9 | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.500 | |
| 3vs0 | VS0 | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.500 | |
| 1u54 | ACP | Activated CDC42 kinase 1 | / | 0.499 | |
| 3vry | B43 | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.499 | |
| 5e8w | STU | TGF-beta receptor type-1 | 2.7.11.30 | 0.499 | |
| 2c0o | L2G | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.498 | |
| 3bbt | FMM | Receptor tyrosine-protein kinase erbB-4 | 2.7.10.1 | 0.498 | |
| 4c4g | 7RO | Dual specificity protein kinase TTK | 2.7.12.1 | 0.498 | |
| 3poz | 03P | Epidermal growth factor receptor | 2.7.10.1 | 0.496 | |
| 4bid | IE8 | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.493 | |
| 4hjo | AQ4 | Epidermal growth factor receptor | 2.7.10.1 | 0.492 | |
| 4ks8 | B49 | Serine/threonine-protein kinase PAK 6 | 2.7.11.1 | 0.492 | |
| 3b8r | 887 | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.490 | |
| 4zse | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.490 | |
| 1xjd | STU | Protein kinase C theta type | 2.7.11.13 | 0.489 | |
| 3v5l | 0G1 | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.489 | |
| 3vs3 | VSE | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.489 | |
| 4fr4 | STU | Serine/threonine-protein kinase 32A | 2.7.11.1 | 0.489 | |
| 4c4h | 7RO | Dual specificity protein kinase TTK | 2.7.12.1 | 0.488 | |
| 4dgg | I76 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.488 | |
| 3jxw | LXG | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.487 | |
| 2dq7 | STU | Tyrosine-protein kinase Fyn | 2.7.10.2 | 0.486 | |
| 3bgq | VX2 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.486 | |
| 3qlf | PD5 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.486 | |
| 4bgg | 844 | Activin receptor type-1 | 2.7.11.30 | 0.486 | |
| 1yi3 | LY2 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.485 | |
| 2ivu | ZD6 | Proto-oncogene tyrosine-protein kinase receptor Ret | 2.7.10.1 | 0.485 | |
| 4kb8 | 1QN | Casein kinase I isoform delta | 2.7.11.1 | 0.485 | |
| 2ivv | PP1 | Proto-oncogene tyrosine-protein kinase receptor Ret | 2.7.10.1 | 0.484 | |
| 4fod | 0UV | ALK tyrosine kinase receptor | 2.7.10.1 | 0.484 | |
| 1xkk | FMM | Epidermal growth factor receptor | 2.7.10.1 | 0.483 | |
| 4enx | Z20 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.483 | |
| 4fob | 0US | ALK tyrosine kinase receptor | 2.7.10.1 | 0.483 | |
| 5ajq | DB8 | Serine/threonine-protein kinase 10 | 2.7.11.1 | 0.483 | |
| 4bf2 | STU | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.482 | |
| 4fv9 | E71 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.482 | |
| 4hvh | 19R | Tyrosine-protein kinase JAK3 | 2.7.10.2 | 0.482 | |
| 2xp2 | VGH | ALK tyrosine kinase receptor | 2.7.10.1 | 0.481 | |
| 2yir | YIR | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.481 | |
| 3say | OFT | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.481 | |
| 3tti | KBI | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.481 | |
| 4ft7 | H3K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.481 | |
| 2exc | JNK | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.480 | |
| 3uyt | 0CK | Casein kinase I isoform delta | 2.7.11.1 | 0.480 | |
| 1byg | STU | Tyrosine-protein kinase CSK | / | 0.479 | |
| 2xa4 | AZ5 | Tyrosine-protein kinase JAK2 | / | 0.479 | |
| 3f69 | XDR | Serine/threonine-protein kinase PknB | 2.7.11.1 | 0.479 | |
| 2bdf | 24A | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.478 | |
| 2yit | YIT | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.478 | |
| 4wkq | IRE | Epidermal growth factor receptor | 2.7.10.1 | 0.478 | |
| 3gub | GUB | Death-associated protein kinase 1 | 2.7.11.1 | 0.477 | |
| 3mfs | ANP | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.477 | |
| 3w2r | W2R | Epidermal growth factor receptor | 2.7.10.1 | 0.477 | |
| 1stc | STU | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.476 | |
| 2h96 | 893 | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.476 | |
| 2nry | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.476 | |
| 1u4d | DBQ | Activated CDC42 kinase 1 | / | 0.475 | |
| 3lj3 | WYE | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.475 | |
| 4k18 | 1OB | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.475 | |
| 4o0r | X4Z | Serine/threonine-protein kinase PAK 1 | 2.7.11.1 | 0.475 | |
| 1szm | BI4 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.474 | |
| 1yhs | STU | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.474 | |
| 2itt | AEE | Epidermal growth factor receptor | 2.7.10.1 | 0.474 | |
| 3v5j | 0F2 | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.474 | |
| 4jbq | VX6 | Aurora kinase A | 2.7.11.1 | 0.474 | |
| 4l7s | G7K | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.474 | |
| 4gih | 0X5 | Non-receptor tyrosine-protein kinase TYK2 | 2.7.10.2 | 0.473 | |
| 2cdz | 23D | Serine/threonine-protein kinase PAK 4 | 2.7.11.1 | 0.472 | |
| 2gcd | STU | Serine/threonine-protein kinase TAO2 | 2.7.11.1 | 0.472 | |
| 2j0m | 4ST | Focal adhesion kinase 1 | 2.7.10.2 | 0.472 | |
| 4kbk | 1QG | Casein kinase I isoform delta | 2.7.11.1 | 0.472 | |
| 4u97 | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.472 | |
| 2nru | T12 | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.471 | |
| 3bgp | VX1 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.471 | |
| 3ggf | GVD | Serine/threonine-protein kinase 26 | / | 0.471 | |
| 3t2z | FAD | Sulfide-quinone reductase | / | 0.471 | |
| 2w7x | D1A | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.470 | |
| 4c3f | 7KW | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.470 | |
| 4erw | STU | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.470 | |
| 2iw8 | 4SP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.469 | |
| 2izr | BRK | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.469 | |
| 4fny | I3K | ALK tyrosine kinase receptor | 2.7.10.1 | 0.469 | |
| 4fux | E75 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.469 | |
| 4hge | 15V | Tyrosine-protein kinase JAK2 | / | 0.469 | |
| 1jpa | ANP | Ephrin type-B receptor 2 | 2.7.10.1 | 0.468 | |
| 3r2b | 05B | MAP kinase-activated protein kinase 2 | 2.7.11.1 | 0.467 | |
| 2gs7 | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.466 | |
| 2uzl | C94 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.466 | |
| 3uvq | FS8 | Mitogen-activated protein kinase 14 | / | 0.466 | |
| 4c34 | STU | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.466 | |
| 4hni | 16W | Casein kinase I isoform epsilon | 2.7.11.1 | 0.466 | |
| 4i0s | 1B5 | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.466 | |
| 1yol | S03 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.465 | |
| 2obj | VRV | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.465 | |
| 2w0j | ZAT | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.465 | |
| 3bkb | STU | Tyrosine-protein kinase Fes/Fps | 2.7.10.2 | 0.465 | |
| 3l8p | 0CE | Angiopoietin-1 receptor | 2.7.10.1 | 0.465 | |
| 4hvi | 19S | Tyrosine-protein kinase JAK3 | 2.7.10.2 | 0.465 | |
| 2itz | IRE | Epidermal growth factor receptor | 2.7.10.1 | 0.464 | |
| 2q5g | 1FA | Peroxisome proliferator-activated receptor delta | / | 0.464 | |
| 4fv7 | E94 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.464 | |
| 4hnf | 16W | Casein kinase I isoform delta | 2.7.11.1 | 0.464 | |
| 4lmu | QUE | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.464 | |
| 1g5s | I17 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.463 | |
| 1qpd | STU | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.463 | |
| 4aoj | V4Z | High affinity nerve growth factor receptor | 2.7.10.1 | 0.463 | |
| 2bdj | HET | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.462 | |
| 2iw9 | 4SP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.462 | |
| 2o0u | C0M | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.462 | |
| 3cbl | STU | Tyrosine-protein kinase Fes/Fps | 2.7.10.2 | 0.462 | |
| 4aot | GW8 | Serine/threonine-protein kinase 10 | 2.7.11.1 | 0.462 | |
| 4b99 | R4L | Mitogen-activated protein kinase 7 | 2.7.11.24 | 0.462 | |
| 1ad5 | ANP | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.461 | |
| 1vjy | 460 | TGF-beta receptor type-1 | 2.7.11.30 | 0.461 | |
| 2c47 | 5ID | Casein kinase I isoform gamma-2 | / | 0.461 | |
| 4jq7 | KJQ | Epidermal growth factor receptor | 2.7.10.1 | 0.461 | |
| 4l52 | 1UL | Mitogen-activated protein kinase kinase kinase 7 | 2.7.11.25 | 0.461 | |
| 1oi9 | N20 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.460 | |
| 2j0j | 4ST | Focal adhesion kinase 1 | 2.7.10.2 | 0.460 | |
| 3f5p | 741 | Insulin-like growth factor 1 receptor | 2.7.10.1 | 0.460 | |
| 3kf7 | L9G | Mitogen-activated protein kinase 14 | / | 0.460 | |
| 4jrv | KJV | Epidermal growth factor receptor | 2.7.10.1 | 0.460 | |
| 1m17 | AQ4 | Epidermal growth factor receptor | 2.7.10.1 | 0.459 | |
| 3c7q | XIN | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.459 | |
| 4c62 | XWW | Tyrosine-protein kinase JAK2 | / | 0.459 | |
| 4wbo | ANW | Rhodopsin kinase | / | 0.459 | |
| 4yzc | STU | Serine/threonine-protein kinase/endoribonuclease IRE1 | 2.7.11.1 | 0.459 | |
| 3a60 | STU | Ribosomal protein S6 kinase beta-1 | 2.7.11.1 | 0.458 | |
| 3uzp | 0CK | Casein kinase I isoform delta | 2.7.11.1 | 0.458 | |
| 4gfo | 0X2 | Non-receptor tyrosine-protein kinase TYK2 | 2.7.10.2 | 0.458 | |
| 4kio | G5K | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.458 | |
| 4n70 | 2HX | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.458 | |
| 3at4 | CCK | Casein kinase II subunit alpha | 2.7.11.1 | 0.457 | |
| 3zze | 6XP | Hepatocyte growth factor receptor | 2.7.10.1 | 0.457 | |
| 4gj2 | 0XH | Non-receptor tyrosine-protein kinase TYK2 | 2.7.10.2 | 0.457 | |
| 4jr3 | KJR | Epidermal growth factor receptor | 2.7.10.1 | 0.457 | |
| 4mxy | DB8 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.457 | |
| 4mxz | DB8 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.457 | |
| 4nka | 2K7 | Fibroblast growth factor receptor 1 | / | 0.457 | |
| 2itn | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.456 | |
| 3aox | EMH | ALK tyrosine kinase receptor | 2.7.10.1 | 0.456 | |
| 3cd3 | STU | Tyrosine-protein kinase Fes/Fps | 2.7.10.2 | 0.456 | |
| 3l1s | Z92 | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.456 | |
| 3ogq | AB1 | Pol polyprotein | / | 0.456 | |
| 4dfl | 0K0 | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.456 | |
| 4dfn | 0K1 | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.456 | |
| 4dym | IYZ | Activin receptor type-1 | 2.7.11.30 | 0.456 | |
| 4eor | 4SP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.456 | |
| 4f4p | 0SB | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.456 | |
| 2hy8 | 1ST | Serine/threonine-protein kinase PAK 1 | 2.7.11.1 | 0.455 | |
| 3oom | 507 | Activin receptor type-1 | 2.7.11.30 | 0.455 | |
| 3qk0 | QK0 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.455 | |
| 3t2y | FAD | Sulfide-quinone reductase | / | 0.455 | |
| 4cki | ADN | Proto-oncogene tyrosine-protein kinase receptor Ret | 2.7.10.1 | 0.455 | |
| 4kb8 | 1QO | Casein kinase I isoform delta | 2.7.11.1 | 0.455 | |
| 2cgw | 3C3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.454 | |
| 2hxl | 422 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.454 | |
| 2vx0 | 7X7 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.454 | |
| 3r04 | UNQ | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.454 | |
| 4acc | 7YG | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.454 | |
| 4dit | 0KD | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.454 | |
| 4feq | 0T8 | Tyrosine-protein kinase receptor TYRO3 | 2.7.10.1 | 0.454 | |
| 4jia | 1K3 | Tyrosine-protein kinase JAK2 | / | 0.454 | |
| 4qmx | H8H | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.454 | |
| 2xm9 | LWH | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.453 | |
| 3gxl | QIG | TGF-beta receptor type-1 | 2.7.11.30 | 0.453 | |
| 3tuc | FPW | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.453 | |
| 3w18 | N13 | Aurora kinase A | 2.7.11.1 | 0.453 | |
| 4c58 | 824 | Cyclin-G-associated kinase | 2.7.11.1 | 0.453 | |
| 4ftk | H9K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.453 | |
| 4gk2 | L66 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.453 | |
| 4gmy | 0X5 | Tyrosine-protein kinase JAK2 | / | 0.453 | |
| 4oa9 | ANP | Protein BRASSINOSTEROID INSENSITIVE 1 | 2.7.10.1 | 0.453 | |
| 4wsq | KSA | AP2-associated protein kinase 1 | 2.7.11.1 | 0.453 | |
| 5amn | DTQ | Proto-oncogene tyrosine-protein kinase receptor Ret | 2.7.10.1 | 0.453 | |
| 5ar4 | SB2 | Receptor-interacting serine/threonine-protein kinase 2 | 2.7.11.1 | 0.453 | |
| 5awm | ANP | Stress-activated protein kinase JNK | 2.7.11.24 | 0.453 | |
| 1di8 | DTQ | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.452 | |
| 2b1p | AIZ | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.452 | |
| 3hmm | 855 | TGF-beta receptor type-1 | 2.7.11.30 | 0.452 | |
| 3vbq | 0F5 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.452 | |
| 4eny | J19 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.452 | |
| 4k33 | ACP | Fibroblast growth factor receptor 3 | 2.7.10.1 | 0.452 | |
| 4qmp | DKI | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.452 | |
| 1h1s | 4SP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.451 | |
| 1qpj | STU | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.451 | |
| 2wtd | ZZK | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.451 | |
| 2x1n | X1N | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.451 | |
| 2x2m | X2M | Proto-oncogene tyrosine-protein kinase receptor Ret | 2.7.10.1 | 0.451 | |
| 3a4o | STU | Tyrosine-protein kinase Lyn | 2.7.10.2 | 0.451 | |
| 4jlc | SU6 | Serine/threonine-protein kinase TBK1 | 2.7.11.1 | 0.451 | |
| 4otw | DB8 | Receptor tyrosine-protein kinase erbB-3 | 2.7.10.1 | 0.451 | |
| 1u59 | STU | Tyrosine-protein kinase ZAP-70 | 2.7.10.2 | 0.450 | |
| 1xr1 | ANP | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.450 | |
| 2x2l | X2L | Proto-oncogene tyrosine-protein kinase receptor Ret | 2.7.10.1 | 0.450 | |
| 2yiq | YIQ | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.450 | |
| 3c4e | C4E | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.450 | |
| 3cyl | VIT | Basic phospholipase A2 homolog piratoxin-2 | / | 0.450 | |
| 3t2k | FAD | Sulfide-quinone reductase | / | 0.450 | |
| 3w1f | 1O5 | Dual specificity protein kinase TTK | 2.7.12.1 | 0.450 | |
| 3ofm | 4B0 | Casein kinase II subunit alpha' | 2.7.11.1 | 0.449 | |
| 3umx | Q18 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.449 | |
| 3zh8 | C58 | Protein kinase C iota type | 2.7.11.13 | 0.449 | |
| 4c4f | 7CE | Dual specificity protein kinase TTK | 2.7.12.1 | 0.449 | |
| 4dgn | LU2 | Casein kinase II subunit alpha | 2.7.11.1 | 0.449 | |
| 4eok | 4SP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.449 | |
| 4fv1 | EK4 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.449 | |
| 4gj3 | 0XP | Non-receptor tyrosine-protein kinase TYK2 | 2.7.10.2 | 0.449 | |
| 1h1r | 6CP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.448 | |
| 1idb | 0DO | Gag-Pol polyprotein | / | 0.448 | |
| 1nvq | UCN | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.448 | |
| 2e9u | A25 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.448 | |
| 2vwz | 7X6 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.448 | |
| 3gc9 | B45 | Mitogen-activated protein kinase 11 | 2.7.11.24 | 0.448 | |
| 3jy0 | LYG | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.448 | |
| 3t8o | ATP | Rhodopsin kinase | / | 0.448 | |
| 3ue4 | DB8 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.448 | |
| 4bdb | ODO | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.448 | |
| 4c4i | X20 | Dual specificity protein kinase TTK | 2.7.12.1 | 0.448 | |
| 4fsq | HK3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.448 | |
| 4gii | 0X6 | Non-receptor tyrosine-protein kinase TYK2 | 2.7.10.2 | 0.448 | |
| 1e9h | INR | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.447 | |
| 2b52 | D42 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.447 | |
| 2hog | 710 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.447 | |
| 2o65 | MYF | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.447 | |
| 2phk | ATP | Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform | 2.7.11.19 | 0.447 | |
| 2vx1 | 7X8 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.447 | |
| 2wti | WTI | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.447 | |
| 2y46 | MIV | Mycinamicin IV hydroxylase/epoxidase | / | 0.447 | |
| 2zdt | 46C | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.447 | |
| 3hl7 | I47 | Mitogen-activated protein kinase 14 | / | 0.447 | |
| 4iwq | 1FV | Serine/threonine-protein kinase TBK1 | 2.7.11.1 | 0.447 | |
| 4oac | ADP | Protein BRASSINOSTEROID INSENSITIVE 1 | 2.7.10.1 | 0.447 | |
| 5e8x | STU | TGF-beta receptor type-1 | 2.7.11.30 | 0.447 | |
| 1kbo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.446 | |
| 1y0s | 331 | Peroxisome proliferator-activated receptor delta | / | 0.446 | |
| 2e9v | 85A | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.446 | |
| 2i4p | DRH | Peroxisome proliferator-activated receptor gamma | / | 0.446 | |
| 2j7t | 274 | Serine/threonine-protein kinase 10 | 2.7.11.1 | 0.446 | |
| 2vz6 | FEF | Calcium/calmodulin-dependent protein kinase type II subunit alpha | 2.7.11.17 | 0.446 | |
| 2xj1 | XJ1 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.446 | |
| 3bu5 | ATP | Insulin receptor | 2.7.10.1 | 0.446 | |
| 3cy2 | MB9 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.446 | |
| 3zc6 | VFC | Tyrosine-protein kinase JAK3 | 2.7.10.2 | 0.446 | |
| 4bzn | UGX | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.446 | |
| 4mxo | DB8 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.446 | |
| 1m2p | HNA | Casein kinase II subunit alpha | 2.7.11.1 | 0.445 | |
| 2jkq | VG8 | Focal adhesion kinase 1 | 2.7.10.2 | 0.445 | |
| 2q59 | 240 | Peroxisome proliferator-activated receptor gamma | / | 0.445 | |
| 2ym7 | YM7 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.445 | |
| 3she | I85 | MAP kinase-activated protein kinase 3 | 2.7.11.1 | 0.445 | |
| 3zew | STU | Ephrin type-B receptor 4 | 2.7.10.1 | 0.445 | |
| 4c02 | TAK | Activin receptor type-1 | 2.7.11.30 | 0.445 | |
| 4hgl | 0YO | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.445 | |
| 1csn | ATP | Casein kinase I homolog 1 | 2.7.11.1 | 0.444 | |
| 1k6c | MK1 | Gag-Pol polyprotein | 3.4.23.16 | 0.444 | |
| 2etm | 7PY | Focal adhesion kinase 1 | 2.7.10.2 | 0.444 | |
| 2hk5 | 1BM | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.444 | |
| 3be9 | P04 | Casein kinase II subunit alpha | 2.7.11.1 | 0.444 | |
| 3k5u | PFQ | Aurora kinase A | 2.7.11.1 | 0.444 | |
| 3tki | S25 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.444 | |
| 3vth | APC | Carbamoyltransferase | / | 0.444 | |
| 5hes | 032 | Mitogen-activated protein kinase kinase kinase 20 | 2.7.11.25 | 0.444 | |
| 2pvn | P63 | Casein kinase II subunit alpha | 2.7.11.1 | 0.443 | |
| 2vu3 | LZE | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.443 | |
| 2vwy | 7X5 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.443 | |
| 2wtc | VGM | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.443 | |
| 3ncg | BK1 | Calmodulin-domain protein kinase 1, putative | / | 0.443 | |
| 3t14 | FAD | Sulfide-quinone reductase | / | 0.443 | |
| 4anq | VGH | ALK tyrosine kinase receptor | 2.7.10.1 | 0.443 | |
| 4aw3 | MYV | Mycinamicin IV hydroxylase/epoxidase | / | 0.443 | |
| 4bb4 | 32W | Ephrin type-B receptor 4 | 2.7.10.1 | 0.443 | |
| 4nk9 | 2K5 | Fibroblast growth factor receptor 1 | / | 0.443 | |
| 4xx9 | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.443 | |
| 4z61 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.443 | |
| 5aac | VGH | ALK tyrosine kinase receptor | 2.7.10.1 | 0.443 | |
| 1hos | PHP | Gag-Pol polyprotein | / | 0.442 | |
| 1ke6 | LS2 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.442 | |
| 1m2r | MNY | Casein kinase II subunit alpha | 2.7.11.1 | 0.442 | |
| 2brm | DFZ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.442 | |
| 2chl | DKI | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.442 | |
| 3dog | NNN | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.442 | |
| 3dtc | VIN | Mitogen-activated protein kinase kinase kinase 9 | 2.7.11.25 | 0.442 | |
| 3elj | GS7 | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.442 | |
| 4a06 | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.442 | |
| 4c4j | X21 | Dual specificity protein kinase TTK | 2.7.12.1 | 0.442 | |
| 4g2f | C07 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.442 | |
| 4qmt | H1N | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.442 | |
| 2cgx | 3D3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.441 | |
| 2csn | CKI | Casein kinase I homolog 1 | 2.7.11.1 | 0.441 | |
| 2izs | BRQ | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.441 | |
| 2p33 | J07 | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.441 | |
| 2pvl | P55 | Casein kinase II subunit alpha | 2.7.11.1 | 0.441 | |
| 2qo9 | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.441 | |
| 2vwx | 7X4 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.441 | |
| 2xc3 | RT8 | Steroid C26-monooxygenase | 1.14.13.141 | 0.441 | |
| 3at3 | ATK | Casein kinase II subunit alpha | 2.7.11.1 | 0.441 | |
| 3ma3 | 01I | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.441 | |
| 3rk5 | 07Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.441 | |
| 4acg | 6LQ | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.441 | |
| 4bcm | T7Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.441 | |
| 4bkz | 1WS | Maternal embryonic leucine zipper kinase | 2.7.11.1 | 0.441 | |
| 4ftu | 7HK | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.441 | |
| 4iwo | 1H4 | Serine/threonine-protein kinase TBK1 | 2.7.11.1 | 0.441 | |
| 4jbo | WPH | Aurora kinase A | 2.7.11.1 | 0.441 | |
| 4k1b | 1OC | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.441 | |
| 4loq | SB4 | Mitogen-activated protein kinase 14 | / | 0.441 | |
| 1rw8 | 580 | TGF-beta receptor type-1 | 2.7.11.30 | 0.440 | |
| 1sh9 | RIT | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
| 2clq | STU | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.440 | |
| 2itp | AEE | Epidermal growth factor receptor | 2.7.10.1 | 0.440 | |
| 2pvh | P19 | Casein kinase II subunit alpha | 2.7.11.1 | 0.440 | |
| 2wou | ZZF | TGF-beta receptor type-1 | 2.7.11.30 | 0.440 | |
| 2xck | MH4 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.440 | |
| 2zv9 | PP2 | Tyrosine-protein kinase Lyn | 2.7.10.2 | 0.440 | |
| 3a99 | ANP | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.440 | |
| 3cy3 | JN5 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.440 | |
| 3kpk | FAD | Sulfide-quinone reductase | / | 0.440 | |
| 4btk | DTQ | Tau-tubulin kinase 1 | 2.7.11.1 | 0.440 | |
| 4dtk | 7LI | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.440 | |
| 4e4m | 0NH | Tyrosine-protein kinase JAK2 | / | 0.440 | |
| 4g6n | EK0 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.440 | |
| 4lop | SB4 | Mitogen-activated protein kinase 14 | / | 0.440 | |
| 5dgz | L20 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.440 |