sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4dlx | GNP | GTPase HRas |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 4dlx | GNP | GTPase HRas | / | 1.000 | |
| 2rgc | GNP | GTPase HRas | / | 0.912 | |
| 4dlz | GNP | GTPase HRas | / | 0.890 | |
| 3rs5 | GNP | GTPase HRas | / | 0.877 | |
| 4dlv | GNP | GTPase HRas | / | 0.863 | |
| 3oiv | GNP | GTPase HRas | / | 0.831 | |
| 2rgb | GNP | GTPase HRas | / | 0.825 | |
| 2rge | GNP | GTPase HRas | / | 0.819 | |
| 3rs0 | GNP | GTPase HRas | / | 0.773 | |
| 4dlw | GNP | GTPase HRas | / | 0.768 | |
| 3rsl | GNP | GTPase HRas | / | 0.757 | |
| 3v4f | GNP | GTPase HRas | / | 0.747 | |
| 3rs7 | GNP | GTPase HRas | / | 0.734 | |
| 3lbn | GNP | GTPase HRas | / | 0.719 | |
| 4dls | GNP | GTPase HRas | / | 0.698 | |
| 2c5l | GTP | GTPase HRas | / | 0.696 | |
| 4nyi | GNP | GTPase HRas | / | 0.685 | |
| 3ddc | GNP | GTPase HRas | / | 0.673 | |
| 3l8y | GNP | GTPase HRas | / | 0.664 | |
| 4l9w | GNP | GTPase HRas | / | 0.664 | |
| 3oiu | GNP | GTPase HRas | / | 0.658 | |
| 3x1z | GNP | Ras-related protein Rap-1b | / | 0.658 | |
| 4nyj | GNP | GTPase HRas | / | 0.653 | |
| 5b2z | GNP | GTPase HRas | / | 0.652 | |
| 1e96 | GTP | Ras-related C3 botulinum toxin substrate 1 | / | 0.644 | |
| 4k81 | GTP | GTPase HRas | / | 0.642 | |
| 3k8y | GNP | GTPase HRas | / | 0.641 | |
| 4hdo | GNP | Ras-related protein Rap-1b | / | 0.640 | |
| 4rkf | GNP | Ras-related protein Rab-3 | / | 0.639 | |
| 3i3s | GNP | GTPase HRas | / | 0.637 | |
| 4g0n | GNP | GTPase HRas | / | 0.634 | |
| 4dsn | GCP | GTPase KRas | / | 0.633 | |
| 3kko | GNP | Ras-related protein M-Ras | / | 0.631 | |
| 3oiw | GNP | GTPase HRas | / | 0.629 | |
| 3pit | GNP | Ras-related protein M-Ras | / | 0.624 | |
| 3kuc | GDP | Ras-related protein Rap-1A | / | 0.615 | |
| 3a6p | GTP | GTP-binding nuclear protein Ran | / | 0.613 | |
| 5dif | GNP | GTP-binding nuclear protein Ran | / | 0.612 | |
| 5jlj | GNP | GTP-binding nuclear protein Ran | / | 0.608 | |
| 3oes | GNP | GTPase RhebL1 | / | 0.607 | |
| 3kud | GDP | GTPase HRas | / | 0.605 | |
| 3w3z | GTP | GTP-binding nuclear protein Ran | / | 0.605 | |
| 4lhw | GNP | Ras-related protein Rab-8A | / | 0.605 | |
| 1zbd | GTP | Ras-related protein Rab-3A | / | 0.601 | |
| 3sbd | GNP | Ras-related C3 botulinum toxin substrate 1 | / | 0.596 | |
| 1ibr | GNP | GTP-binding nuclear protein Ran | / | 0.595 | |
| 1t91 | GTP | Ras-related protein Rab-7a | / | 0.594 | |
| 3ea5 | GDP | GTP-binding nuclear protein Ran | / | 0.593 | |
| 3rs4 | GNP | GTPase HRas | / | 0.593 | |
| 2qme | GCP | Ras-related C3 botulinum toxin substrate 3 | / | 0.591 | |
| 1xts | GTP | GTP-binding protein Rheb | / | 0.590 | |
| 3e5h | GNP | Ras-related protein Rab-28 | / | 0.590 | |
| 3rab | GNP | Ras-related protein Rab-3A | / | 0.587 | |
| 2bku | GTP | GTP-binding nuclear protein Ran | / | 0.581 | |
| 3lbh | GNP | GTPase HRas | / | 0.576 | |
| 1m7b | GTP | Rho-related GTP-binding protein RhoE | / | 0.574 | |
| 2gcp | GSP | Rho-related GTP-binding protein RhoC | / | 0.574 | |
| 3bbp | GTP | Ras-related protein Rab-6A | / | 0.572 | |
| 1g17 | GNP | Ras-related protein SEC4 | / | 0.569 | |
| 1xtr | GNP | GTP-binding protein Rheb | / | 0.569 | |
| 1zc4 | GNP | Ras-related protein Ral-A | / | 0.569 | |
| 4l9s | GDP | GTPase HRas | / | 0.569 | |
| 2x19 | GTP | GTP-binding nuclear protein GSP1/CNR1 | / | 0.566 | |
| 1yzq | GNP | Ras-related protein Rab-6A | / | 0.564 | |
| 1zc3 | GNP | Ras-related protein Ral-A | / | 0.564 | |
| 4l8g | GDP | GTPase KRas | / | 0.564 | |
| 1cxz | GSP | Transforming protein RhoA | / | 0.563 | |
| 4dlt | GNP | GTPase HRas | / | 0.563 | |
| 3tnf | GNP | Ras-related protein Rab-8A | / | 0.559 | |
| 4dso | GSP | GTPase KRas | / | 0.559 | |
| 4mit | GTP | Rho-related protein racC | / | 0.559 | |
| 1zd9 | GDP | ADP-ribosylation factor-like protein 8A | / | 0.557 | |
| 3nbz | GTP | GTP-binding nuclear protein Ran | / | 0.557 | |
| 4ol0 | GTP | GTP-binding nuclear protein Ran | / | 0.557 | |
| 1yhn | GTP | Ras-related protein Rab-7a | / | 0.556 | |
| 5dha | GNP | GTP-binding nuclear protein Ran | / | 0.554 | |
| 2fe4 | GDP | Ras-related protein Rab-6B | / | 0.552 | |
| 2fju | GSP | Ras-related C3 botulinum toxin substrate 1 | / | 0.552 | |
| 3lbi | GNP | GTPase HRas | / | 0.552 | |
| 4tq9 | GDP | GTPase KRas | / | 0.552 | |
| 1kmq | GNP | Transforming protein RhoA | / | 0.551 | |
| 4hdq | GNP | Ras-related protein Rap-1b | / | 0.551 | |
| 1mh1 | GNP | Ras-related C3 botulinum toxin substrate 1 | / | 0.550 | |
| 3sbe | GNP | Ras-related C3 botulinum toxin substrate 1 | / | 0.550 | |
| 4kvg | GTP | Ras-related protein Rap-1A | / | 0.550 | |
| 3a58 | GNP | GTP-binding protein RHO1 | / | 0.549 | |
| 1s1c | GNP | Transforming protein RhoA | / | 0.547 | |
| 1vg8 | GNP | Ras-related protein Rab-7a | / | 0.547 | |
| 2msd | GNP | MHC class I alpha chain | / | 0.547 | |
| 3wyg | GTP | GTP-binding nuclear protein GSP1/CNR1 | / | 0.546 | |
| 4lv6 | GDP | GTPase KRas | / | 0.546 | |
| 3bc1 | GNP | Ras-related protein Rab-27A | / | 0.544 | |
| 3tso | GNP | Ras-related protein Rab-25 | / | 0.543 | |
| 3wyf | GTP | GTP-binding nuclear protein | / | 0.542 | |
| 4o25 | GTP | GTP-binding protein Rheb | / | 0.542 | |
| 4dxa | GSP | Ras-related protein Rap-1b | / | 0.541 | |
| 3tgp | GNP | GTPase HRas | / | 0.540 | |
| 4epx | GDP | GTPase KRas | / | 0.540 | |
| 4epw | GDP | GTPase KRas | / | 0.539 | |
| 4obe | GDP | GTPase KRas | / | 0.539 | |
| 2gil | GTP | Ras-related protein Rab-6A | / | 0.538 | |
| 4js0 | GNP | Cell division control protein 42 homolog | / | 0.538 | |
| 2ce2 | GDP | GTPase HRas | / | 0.536 | |
| 4q02 | GDP | GTPase KRas | / | 0.533 | |
| 4ldj | GDP | GTPase KRas | / | 0.532 | |
| 4ql3 | GDP | GTPase KRas | / | 0.530 | |
| 4gzl | GNP | Ras-related C3 botulinum toxin substrate 1 | / | 0.529 | |
| 1a2b | GSP | Transforming protein RhoA | / | 0.527 | |
| 1lfd | GNP | GTPase HRas | / | 0.527 | |
| 4o2l | GTP | GTP-binding protein Rheb | / | 0.527 | |
| 2ov2 | GCP | Ras-related C3 botulinum toxin substrate 3 | / | 0.526 | |
| 4q03 | GDP | GTPase KRas | / | 0.525 | |
| 4qxa | GTP | Ras-related protein Rab-9A | / | 0.524 | |
| 4xvr | GNP | GTPase HRas | / | 0.524 | |
| 3cph | GDP | Ras-related protein SEC4 | / | 0.523 | |
| 3th5 | GNP | Ras-related C3 botulinum toxin substrate 1 | / | 0.523 | |
| 4wa7 | GDP | GTPase KRas | / | 0.523 | |
| 4luc | GDP | GTPase KRas | / | 0.521 | |
| 3kkq | GDP | Ras-related protein M-Ras | / | 0.520 | |
| 1ow3 | GDP | Transforming protein RhoA | / | 0.518 | |
| 1k5d | GNP | GTP-binding nuclear protein Ran | / | 0.517 | |
| 3x1w | GDP | Ras-related protein Rap-1b | / | 0.515 | |
| 2w2x | GSP | Ras-related C3 botulinum toxin substrate 2 | / | 0.514 | |
| 1yu9 | GNP | Ras-related protein Rab-4A | / | 0.513 | |
| 2msc | GDP | MHC class I alpha chain | / | 0.513 | |
| 1gwn | GTP | Rho-related GTP-binding protein RhoE | / | 0.512 | |
| 1d5c | GDP | GTPase (Rab6) | / | 0.511 | |
| 4lpk | GDP | GTPase KRas | / | 0.511 | |
| 1oix | GDP | Ras-related protein Rab-11A | / | 0.510 | |
| 3kz1 | GSP | Transforming protein RhoA | / | 0.510 | |
| 3c14 | FOK | Adenylate cyclase type 2 | / | 0.507 | |
| 3c14 | FOK | Adenylate cyclase type 5 | / | 0.507 | |
| 4o2r | GDP | GTP-binding protein Rheb | / | 0.506 | |
| 1z2a | GDP | Ras-related protein Rab-23 | / | 0.505 | |
| 4xvq | GNP | GTPase HRas | / | 0.505 | |
| 1x1r | GDP | Ras-related protein M-Ras | / | 0.503 | |
| 3k9l | GNP | GTPase HRas | / | 0.503 | |
| 2mse | GNP | MHC class I alpha chain | / | 0.502 | |
| 4cid | ANP | EH domain-containing protein 2 | / | 0.501 | |
| 4uj3 | GNP | Ras-related protein Rab-11A | / | 0.500 | |
| 2rgg | GNP | GTPase HRas | / | 0.499 | |
| 4dsu | GDP | GTPase KRas | / | 0.497 | |
| 2bme | GNP | Ras-related protein Rab-4A | / | 0.495 | |
| 2gvd | FKP | Adenylate cyclase type 2 | / | 0.494 | |
| 2gvd | FKP | Adenylate cyclase type 5 | / | 0.494 | |
| 5hpy | GDP | Transforming protein RhoA | / | 0.494 | |
| 1z0d | GDP | Ras-related protein Rab-5C | / | 0.492 | |
| 3qbt | GNP | Ras-related protein Rab-8A | / | 0.490 | |
| 1uad | GNP | Ras-related protein Ral-A | / | 0.489 | |
| 3nmp | PYV | Abscisic acid receptor PYL2 | / | 0.488 | |
| 3mjh | GTP | Ras-related protein Rab-5A | / | 0.486 | |
| 1z0a | GDP | Ras-related protein Rab-2A | / | 0.484 | |
| 2cl6 | CAG | GTPase HRas | / | 0.483 | |
| 4lrw | GDP | GTPase KRas | / | 0.483 | |
| 5c46 | GSP | Ras-related protein Rab-11A | / | 0.483 | |
| 1fdw | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.482 | |
| 2fg5 | GNP | Ras-related protein Rab-31 | / | 0.482 | |
| 3eg5 | GNP | Cell division control protein 42 homolog | / | 0.482 | |
| 3gmd | 2M3 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.482 | |
| 2p2l | GDP | Ras-related C3 botulinum toxin substrate 1 | / | 0.481 | |
| 1n6l | GTP | Ras-related protein Rab-5A | / | 0.480 | |
| 1z2c | GNP | Rho-related GTP-binding protein RhoC | / | 0.480 | |
| 2fhj | MFN | Formylmethanofuran--tetrahydromethanopterin formyltransferase | 2.3.1.101 | 0.476 | |
| 2a9y | 26A | Adenosine kinase | 2.7.1.20 | 0.475 | |
| 3maa | FKP | Adenylate cyclase type 2 | / | 0.475 | |
| 3maa | FKP | Adenylate cyclase type 5 | / | 0.475 | |
| 4nte | FAD | DepH | / | 0.475 | |
| 2vcz | VC3 | Hematopoietic prostaglandin D synthase | / | 0.473 | |
| 4xoi | GTP | Transforming protein RhoA | / | 0.473 | |
| 2g0n | GDP | Ras-related C3 botulinum toxin substrate 3 | / | 0.472 | |
| 4mv1 | ADP | Biotin carboxylase | 6.3.4.14 | 0.472 | |
| 1cju | FOK | Adenylate cyclase type 2 | / | 0.471 | |
| 1cju | FOK | Adenylate cyclase type 5 | / | 0.471 | |
| 1mrq | STR | Aldo-keto reductase family 1 member C1 | / | 0.471 | |
| 2p1u | 4TN | Retinoic acid receptor RXR-alpha | / | 0.471 | |
| 3pqb | VGP | Putative oxidoreductase | / | 0.471 | |
| 5iub | CLR | Adenosine receptor A2a | / | 0.470 | |
| 1kph | SAH | Cyclopropane mycolic acid synthase 1 | 2.1.1.79 | 0.469 | |
| 3w0a | DS5 | Vitamin D3 receptor | / | 0.469 | |
| 5g53 | NEC | Adenosine receptor A2a | / | 0.469 | |
| 1g16 | GDP | Ras-related protein SEC4 | / | 0.468 | |
| 3tkl | GTP | Ras-related protein Rab-1A | / | 0.468 | |
| 1cjv | FOK | Adenylate cyclase type 2 | / | 0.467 | |
| 1cjv | FOK | Adenylate cyclase type 5 | / | 0.467 | |
| 1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.467 | |
| 2ham | C33 | Vitamin D3 receptor | / | 0.467 | |
| 3hz5 | Z64 | Heat shock protein HSP 90-alpha | / | 0.467 | |
| 4jda | A9S | Abscisic acid receptor PYL3 | / | 0.467 | |
| 1ay0 | TPP | Transketolase 1 | 2.2.1.1 | 0.466 | |
| 2bf7 | HBI | Pteridine reductase 1 | 1.5.1.33 | 0.466 | |
| 4edz | 0O5 | Hematopoietic prostaglandin D synthase | / | 0.466 | |
| 2a0x | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.465 | |
| 5k2b | ZMA | Adenosine receptor A2a | / | 0.465 | |
| 2zb8 | IMN | Prostaglandin reductase 2 | 1.3.1.48 | 0.464 | |
| 3f0a | ACO | Spermidine N(1)-acetyltransferase | / | 0.464 | |
| 3q44 | D50 | M1 family aminopeptidase | 3.4.11 | 0.464 | |
| 5k2d | ZMA | Adenosine receptor A2a | / | 0.464 | |
| 1cjt | FOK | Adenylate cyclase type 2 | / | 0.463 | |
| 1cjt | FOK | Adenylate cyclase type 5 | / | 0.463 | |
| 2oeg | UPG | UDP-glucose pyrophosphorylase | / | 0.463 | |
| 1cul | FOK | Adenylate cyclase type 2 | / | 0.462 | |
| 1cul | FOK | Adenylate cyclase type 5 | / | 0.462 | |
| 1ie9 | VDX | Vitamin D3 receptor | / | 0.462 | |
| 1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.462 | |
| 1pqc | 444 | Oxysterols receptor LXR-beta | / | 0.462 | |
| 1rsz | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.462 | |
| 2a9z | 26A | Adenosine kinase | 2.7.1.20 | 0.462 | |
| 5h8t | RTL | Retinol-binding protein 1 | / | 0.462 | |
| 1cjk | FOK | Adenylate cyclase type 2 | / | 0.461 | |
| 1cjk | FOK | Adenylate cyclase type 5 | / | 0.461 | |
| 1tu3 | GNP | Ras-related protein Rab-5A | / | 0.461 | |
| 4ite | TEY | Vitamin D3 receptor | / | 0.461 | |
| 4ead | 0NP | Thymidine phosphorylase | 2.4.2.4 | 0.460 | |
| 4q0a | 4OA | Vitamin D3 receptor A | / | 0.460 | |
| 3sn6 | P0G | Beta-2 adrenergic receptor | / | 0.460 | |
| 3t1t | GDP | Probable gliding protein mglA | / | 0.459 | |
| 1n83 | CLR | Nuclear receptor ROR-alpha | / | 0.458 | |
| 1u0h | FOK | Adenylate cyclase type 2 | / | 0.458 | |
| 1u0h | FOK | Adenylate cyclase type 5 | / | 0.458 | |
| 3w0c | 6DS | Vitamin D3 receptor | / | 0.458 | |
| 3eml | ZMA | Adenosine receptor A2a | / | 0.458 | |
| 1qjf | ACS | Isopenicillin N synthase | 1.21.3.1 | 0.457 | |
| 2p1v | 5TN | Retinoic acid receptor RXR-alpha | / | 0.457 | |
| 2zru | FMN | Isopentenyl-diphosphate delta-isomerase | / | 0.457 | |
| 1qyw | 5SD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.456 | |
| 1zg3 | 2HI | Isoflavone 4'-O-methyltransferase | / | 0.456 | |
| 2ffq | GSP | Ras-related protein Rab-6B | / | 0.456 | |
| 3neg | PYV | Abscisic acid receptor PYL1 | / | 0.456 | |
| 4nh8 | 2LC | Heat shock protein HSP 90-alpha | / | 0.456 | |
| 4ykl | GMP | Aprataxin-like protein | 3 | 0.456 | |
| 5iu8 | 6DZ | Adenosine receptor A2a | / | 0.456 | |
| 5k2c | ZMA | Adenosine receptor A2a | / | 0.456 | |
| 1bzf | TMQ | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 1ysi | N3B | Bcl-2-like protein 1 | / | 0.455 | |
| 2ic5 | GDP | Ras-related C3 botulinum toxin substrate 3 | / | 0.455 | |
| 2zet | GTP | Ras-related protein Rab-27B | / | 0.455 | |
| 3o6o | 94M | Heat shock protein 83 | / | 0.455 | |
| 4epq | 0RR | Poly(ADP-ribose) glycohydrolase | / | 0.455 | |
| 4lb2 | DM5 | Serum albumin | / | 0.455 | |
| 1db1 | VDX | Vitamin D3 receptor | / | 0.454 | |
| 1fdu | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.454 | |
| 2e98 | B29 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.454 | |
| 3p3z | P3Z | Putative cytochrome P450 | / | 0.454 | |
| 1jtv | TES | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.453 | |
| 1s19 | MC9 | Vitamin D3 receptor | / | 0.453 | |
| 1z71 | L17 | Prothrombin | 3.4.21.5 | 0.453 | |
| 2fm0 | M98 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.453 | |
| 3lq2 | TDP | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.453 | |
| 1bwl | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.452 | |
| 1v8k | ANP | Kinesin-like protein KIF2C | / | 0.452 | |
| 2z9d | FMN | FMN-dependent NADH-azoreductase | / | 0.452 | |
| 3sqx | ANP | ATP-dependent RNA helicase MSS116, mitochondrial | 3.6.4.13 | 0.452 | |
| 4kp6 | 1S1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.452 | |
| 4la7 | A1O | Abscisic acid receptor PYL2 | / | 0.452 | |
| 4xg1 | LLP | Diaminopimelate decarboxylase | / | 0.452 | |
| 2rbe | ZMG | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.451 | |
| 3fnh | JPJ | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.451 | |
| 3qiz | QI2 | Botulinum neurotoxin type A | 3.4.24.69 | 0.451 | |
| 4ihj | GTP | Tubulin alpha-1B chain | / | 0.451 | |
| 5iu4 | ZMA | Adenosine receptor A2a | / | 0.451 | |
| 1d3p | BT3 | Prothrombin | 3.4.21.5 | 0.450 | |
| 2w6o | OA3 | Biotin carboxylase | 6.3.4.14 | 0.450 | |
| 2xk6 | EQH | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.450 | |
| 2zpa | ADP | tRNA(Met) cytidine acetyltransferase TmcA | / | 0.450 | |
| 3vt4 | 5YI | Vitamin D3 receptor | / | 0.450 | |
| 4l09 | 1UR | Tankyrase-2 | 2.4.2.30 | 0.450 | |
| 4u9z | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.450 | |
| 5k2a | ZMA | Adenosine receptor A2a | / | 0.450 | |
| 1l2j | ETC | Estrogen receptor beta | / | 0.449 | |
| 1pq6 | 965 | Oxysterols receptor LXR-beta | / | 0.449 | |
| 1pwy | AC2 | Purine nucleoside phosphorylase | 2.4.2.1 | 0.449 | |
| 2vcq | D25 | Hematopoietic prostaglandin D synthase | / | 0.449 | |
| 2xau | ADP | Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP43 | 3.6.4.13 | 0.449 | |
| 2xtz | GSP | Guanine nucleotide-binding protein alpha-1 subunit | / | 0.449 | |
| 2bfp | H4B | Pteridine reductase 1 | 1.5.1.33 | 0.448 | |
| 2ic5 | GNP | Ras-related C3 botulinum toxin substrate 3 | / | 0.448 | |
| 3djf | BC3 | Purine nucleoside phosphorylase | / | 0.448 | |
| 3ikt | NAD | Redox-sensing transcriptional repressor Rex | / | 0.448 | |
| 3njo | PYV | Abscisic acid receptor PYR1 | / | 0.448 | |
| 4g1y | 0VO | Vitamin D3 receptor A | / | 0.448 | |
| 4h6z | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.448 | |
| 4uj5 | GNP | Ras-related protein Rab-11A | / | 0.448 | |
| 4zzi | 1NS | NAD-dependent protein deacetylase sirtuin-1 | 3.5.1 | 0.448 | |
| 1fds | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.447 | |
| 1lp4 | ANP | Casein kinase II subunit alpha | 2.7.11.1 | 0.447 | |
| 2rdn | 1PL | 1-deoxypentalenic acid 11-beta-hydroxylase | 1.14.11.35 | 0.447 | |
| 4n4v | 2GY | Tankyrase-1 | 2.4.2.30 | 0.447 | |
| 4rra | A3T | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.447 | |
| 4rrr | A3T | Threonine--tRNA ligase | 6.1.1.3 | 0.447 | |
| 4s1i | PLP | Pyridoxal kinase, putative | / | 0.447 | |
| 2vcw | ZZA | Hematopoietic prostaglandin D synthase | / | 0.446 | |
| 2y6f | M9F | Isopenicillin N synthase | 1.21.3.1 | 0.446 | |
| 3zu2 | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.446 | |
| 3zvu | A8S | Abscisic acid receptor PYR1 | / | 0.446 | |
| 4h6u | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.446 | |
| 5kf1 | COA | Predicted acetyltransferase | / | 0.446 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.445 | |
| 1rzu | ADP | Glycogen synthase 1 | 2.4.1.21 | 0.445 | |
| 1s0x | C3S | Nuclear receptor ROR-alpha | / | 0.445 | |
| 1zgv | 501 | Prothrombin | 3.4.21.5 | 0.445 | |
| 2acl | L05 | Oxysterols receptor LXR-alpha | / | 0.445 | |
| 3c16 | FOK | Adenylate cyclase type 2 | / | 0.445 | |
| 3c16 | FOK | Adenylate cyclase type 5 | / | 0.445 | |
| 3cob | ADP | Kinesin heavy chain-like protein | / | 0.445 | |
| 3i28 | 34N | Bifunctional epoxide hydrolase 2 | 3.3.2.10 | 0.445 | |
| 3jun | AJD | Phenazine biosynthesis protein A/B | / | 0.445 | |
| 1a4r | GNH | Cell division control protein 42 homolog | / | 0.444 | |
| 2zl9 | VDA | Vitamin D3 receptor | / | 0.444 | |
| 3sqz | COA | Putative hydroxymethylglutaryl-CoA synthase | / | 0.444 | |
| 4rri | A3T | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.444 | |
| 5jtb | ZMA | Adenosine receptor A2a | / | 0.444 | |
| 4uhr | NGI | Adenosine receptor A2a | / | 0.444 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
| 1xom | CIO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.443 | |
| 1xu9 | CPS | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.443 | |
| 2y8l | ADP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.443 | |
| 3ch6 | 311 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.443 | |
| 3dcs | MZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.443 | |
| 3k7m | FAD | 6-hydroxy-L-nicotine oxidase | / | 0.443 | |
| 3vg9 | ZMA | Adenosine receptor A2a | / | 0.443 | |
| 3vi5 | M4M | Hematopoietic prostaglandin D synthase | / | 0.443 | |
| 4n3l | 2FN | Prothrombin | 3.4.21.5 | 0.443 | |
| 4xyb | NDP | Formate dehydrogenase | / | 0.443 | |
| 4yvn | EBS | Spore coat protein A | / | 0.443 | |
| 5kf2 | COA | Predicted acetyltransferase | / | 0.443 | |
| 2y8q | ADP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.442 | |
| 2zi5 | 3L1 | Deoxycytidine kinase | 2.7.1.74 | 0.442 | |
| 3nmn | PYV | Abscisic acid receptor PYL1 | / | 0.442 | |
| 4ehv | 0SJ | Mitogen-activated protein kinase 14 | / | 0.442 | |
| 4fev | PP1 | Aminoglycoside 3'-phosphotransferase AphA1-IAB | / | 0.442 | |
| 4frk | DWD | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 4k5o | 1OT | M1 family aminopeptidase | 3.4.11 | 0.442 | |
| 4k5p | 1OS | M1 family aminopeptidase | 3.4.11 | 0.442 | |
| 4wbn | GTP | Tubulin alpha-1B chain | / | 0.442 | |
| 5bt4 | 2LO | Bromodomain-containing protein 4 | / | 0.442 | |
| 1k7f | IAV | Tryptophan synthase alpha chain | / | 0.441 | |
| 1mvs | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 1o6r | R19 | Squalene--hopene cyclase | 4.2.1.129 | 0.441 | |
| 2fhk | MFN | Formylmethanofuran--tetrahydromethanopterin formyltransferase | 2.3.1.101 | 0.441 | |
| 2r6j | NDP | Eugenol synthase 1 | 1.1.1.318 | 0.441 | |
| 2yy2 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.441 | |
| 3ipq | 965 | Oxysterols receptor LXR-alpha | / | 0.441 | |
| 3ix4 | TX1 | Transcriptional activator protein LasR | / | 0.441 | |
| 4lga | A2O | Abscisic acid receptor PYL2 | / | 0.441 | |
| 1a27 | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.440 | |
| 2ji9 | TPW | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.440 | |
| 2w6q | OA5 | Biotin carboxylase | 6.3.4.14 | 0.440 | |
| 3eig | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 3vf6 | 0H6 | Glucokinase | 2.7.1.2 | 0.440 | |
| 4dsc | A8S | Abscisic acid receptor PYL3 | / | 0.440 | |
| 5iw5 | NMN | NADH pyrophosphatase | / | 0.440 |