sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2ih2 | NEA | Modification methylase TaqI | 2.1.1.72 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 2ih2 | NEA | Modification methylase TaqI | 2.1.1.72 | 1.000 | |
| 1g38 | NEA | Modification methylase TaqI | 2.1.1.72 | 0.607 | |
| 2np7 | NEA | Modification methylase TaqI | 2.1.1.72 | 0.581 | |
| 2ibt | NEA | Modification methylase TaqI | 2.1.1.72 | 0.559 | |
| 3qv2 | SAH | 5-cytosine DNA methyltransferase | / | 0.527 | |
| 4anx | 534 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.493 | |
| 2wdz | NAD | Galactitol dehydrogenase | / | 0.490 | |
| 3flk | NAI | Tartrate dehydrogenase/decarboxylase | 1.1.1.93 | 0.486 | |
| 4ia7 | BIV | Vitamin D3 receptor A | / | 0.483 | |
| 3l0l | HC3 | Nuclear receptor ROR-gamma | / | 0.482 | |
| 1ajv | NMB | Gag-Pol polyprotein | 3.4.23.16 | 0.481 | |
| 3f63 | GTX | Glutathione transferase GST1-4 | / | 0.480 | |
| 1bdr | IM1 | Gag-Pol polyprotein | 3.4.23.16 | 0.478 | |
| 1rfv | ADP | Pyridoxal kinase | 2.7.1.35 | 0.478 | |
| 1mtr | PI6 | Gag-Pol polyprotein | 3.4.23.16 | 0.477 | |
| 3g7j | GTX | Glutathione transferase GST1-4 | / | 0.477 | |
| 4wlo | NAI | Malate dehydrogenase, mitochondrial | 1.1.1.37 | 0.476 | |
| 1ajx | AH1 | Gag-Pol polyprotein | 3.4.23.16 | 0.474 | |
| 2qi5 | MZ7 | Gag-Pol polyprotein | / | 0.473 | |
| 3a99 | ANP | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.473 | |
| 3lzv | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.473 | |
| 1qbu | 846 | Gag-Pol polyprotein | 3.4.23.16 | 0.472 | |
| 2b9w | FAD | Putative aminooxidase | / | 0.472 | |
| 3zk5 | Z18 | Cytochrome P450 monooxygenase PikC | / | 0.472 | |
| 2hc0 | AB2 | Protease | / | 0.471 | |
| 2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.471 | |
| 1yb5 | NAP | Quinone oxidoreductase | 1.6.5.5 | 0.470 | |
| 3ibd | CPZ | Cytochrome P450 2B6 | 1.14.13 | 0.470 | |
| 6upj | NIU | Gag-Pol polyprotein | / | 0.470 | |
| 2cej | 1AH | Pol protein | / | 0.469 | |
| 3r9u | FAD | Thioredoxin reductase | / | 0.469 | |
| 4ia1 | BIV | Vitamin D3 receptor A | / | 0.469 | |
| 2hcd | BIV | Vitamin D3 receptor A | / | 0.468 | |
| 1hvk | A79 | Gag-Pol polyprotein | / | 0.467 | |
| 2fze | APR | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.467 | |
| 2qnn | QN1 | Gag-Pol polyprotein | 3.4.23.16 | 0.467 | |
| 2rkf | AB1 | Pol protein | / | 0.467 | |
| 2upj | U02 | Gag-Pol polyprotein | 3.4.23.16 | 0.467 | |
| 3oxv | 478 | Gag-Pol polyprotein | 3.4.23.16 | 0.467 | |
| 3oxx | DR7 | Gag-Pol polyprotein | 3.4.23.16 | 0.467 | |
| 3s54 | 017 | Protease | / | 0.467 | |
| 3to6 | LYS_CMC | Histone acetyltransferase ESA1 | / | 0.467 | |
| 4tuv | CPZ | Cytochrome P450 119 | 1.14 | 0.467 | |
| 2fxe | DR7 | Gag-Pol polyprotein | 3.4.23.16 | 0.466 | |
| 1c6z | ROC | Protease | / | 0.465 | |
| 1hpo | UNI | Gag-Pol polyprotein | 3.4.23.16 | 0.465 | |
| 2vo0 | M03 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.465 | |
| 9hvp | 0E9 | Gag-Pol polyprotein | / | 0.465 | |
| 1dw6 | 0Q4 | Gag-Pol polyprotein | 3.4.23.16 | 0.464 | |
| 5upj | UIN | Gag-Pol polyprotein | / | 0.464 | |
| 1sg9 | SAM | Release factor glutamine methyltransferase | 2.1.1.297 | 0.463 | |
| 2a7r | 5GP | GMP reductase 2 | / | 0.463 | |
| 2ca0 | PXI | Cytochrome P450 monooxygenase PikC | / | 0.463 | |
| 3ndw | RIT | Gag-Pol polyprotein | 3.4.23.16 | 0.463 | |
| 4ia2 | BIV | Vitamin D3 receptor A | / | 0.463 | |
| 2yir | YIR | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.462 | |
| 3vdq | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.462 | |
| 4b7s | QLE | Cytochrome P450 monooxygenase PikC | / | 0.462 | |
| 4nb6 | 444 | Nuclear receptor ROR-gamma | / | 0.462 | |
| 1d4y | TPV | Gag-Pol polyprotein | 3.4.23.16 | 0.461 | |
| 1jip | KTN | 6-deoxyerythronolide B hydroxylase | / | 0.461 | |
| 1sdu | MK1 | Gag-Pol polyprotein | 3.4.23.16 | 0.461 | |
| 1x7g | NAP | Putative ketoacyl reductase | 1.3.1 | 0.461 | |
| 2j14 | GNI | Peroxisome proliferator-activated receptor delta | / | 0.461 | |
| 3cjq | SAH | Ribosomal protein L11 methyltransferase | 2.1.1 | 0.461 | |
| 3i2l | 2NC | Protease | / | 0.461 | |
| 3vt8 | YI3 | Vitamin D3 receptor | / | 0.461 | |
| 4lch | 1WN | UDP-3-O-acyl-N-acetylglucosamine deacetylase | / | 0.461 | |
| 1bv7 | XV6 | Gag-Pol polyprotein | 3.4.23.16 | 0.460 | |
| 1k6c | MK1 | Gag-Pol polyprotein | 3.4.23.16 | 0.460 | |
| 2i9k | SAH | Modification methylase HhaI | 2.1.1.37 | 0.460 | |
| 2xck | MH4 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.460 | |
| 3djk | G55 | Gag-Pol polyprotein | 3.4.23.16 | 0.460 | |
| 3pt6 | SAH | DNA (cytosine-5)-methyltransferase 1 | 2.1.1.37 | 0.460 | |
| 4b1f | KRH | Glutamate racemase | / | 0.460 | |
| 1d4i | BEG | Gag-Pol polyprotein | 3.4.23.16 | 0.459 | |
| 1iiq | 0ZR | Gag-Pol polyprotein | 3.4.23.16 | 0.459 | |
| 1mui | AB1 | Protease | / | 0.459 | |
| 1p0h | ACO | Mycothiol acetyltransferase | 2.3.1.189 | 0.459 | |
| 1s3z | COA | Aminoglycoside N(6')-acetyltransferase type 1 | / | 0.459 | |
| 3ete | NDP | Glutamate dehydrogenase 1, mitochondrial | 1.4.1.3 | 0.459 | |
| 7mht | SAH | Modification methylase HhaI | 2.1.1.37 | 0.459 | |
| 1hvl | A76 | Gag-Pol polyprotein | / | 0.458 | |
| 2g1p | SAH | DNA adenine methylase | 2.1.1.72 | 0.458 | |
| 3w8e | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.458 | |
| 4bii | PYW | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.458 | |
| 4imp | NDP | Polyketide synthase extender modules 3-4 | / | 0.458 | |
| 4k11 | 0J9 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.458 | |
| 4rto | SFG | DNA adenine methylase | 2.1.1.72 | 0.458 | |
| 1dfo | FFO | Serine hydroxymethyltransferase | 2.1.2.1 | 0.457 | |
| 1npv | L27 | Gag-Pol polyprotein | 3.4.23.16 | 0.457 | |
| 1pr9 | NAP | L-xylulose reductase | 1.1.1.10 | 0.457 | |
| 2d29 | FAD | Acyl-CoA dehydrogenase | / | 0.457 | |
| 2f80 | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.457 | |
| 2har | OCC | Vitamin D3 receptor | / | 0.457 | |
| 3ldf | SAH | Uncharacterized protein | / | 0.457 | |
| 4ia3 | BIV | Vitamin D3 receptor A | / | 0.457 | |
| 4jvf | 17X | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.457 | |
| 1h2b | NAJ | NAD-dependent alcohol dehydrogenase | / | 0.456 | |
| 1nvt | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.456 | |
| 2aid | THK | Gag-Pol polyprotein | 3.4.23.16 | 0.456 | |
| 2qnq | QN3 | Gag-Pol polyprotein | 3.4.23.16 | 0.456 | |
| 3etg | NDP | Glutamate dehydrogenase 1, mitochondrial | 1.4.1.3 | 0.456 | |
| 3saa | 77F | Protease | / | 0.456 | |
| 3t2z | FAD | Sulfide-quinone reductase | / | 0.456 | |
| 3tl9 | ROC | Gag-Pol polyprotein | 3.4.23.16 | 0.456 | |
| 3zpt | M8Y | Gag-Pol polyprotein | 3.4.23.16 | 0.456 | |
| 4gkv | NAD | Alcohol dehydrogenase, propanol-preferring | 1.1.1.1 | 0.456 | |
| 1b16 | NAQ | Alcohol dehydrogenase | 1.1.1.1 | 0.455 | |
| 1g2k | NM1 | Gag-Pol polyprotein | 3.4.23.16 | 0.455 | |
| 1hwr | 216 | Gag-Pol polyprotein | 3.4.23.16 | 0.455 | |
| 1qbs | DMP | Gag-Pol polyprotein | 3.4.23.16 | 0.455 | |
| 2bpv | 1IN | Gag-Pol polyprotein | 3.4.23.16 | 0.455 | |
| 2bpy | 3IN | Gag-Pol polyprotein | 3.4.23.16 | 0.455 | |
| 2qd8 | 065 | Gag-Pol polyprotein | 3.4.23.16 | 0.455 | |
| 3ggx | GGX | Gag-Pol polyprotein | / | 0.455 | |
| 3sa3 | 23X | Protease | / | 0.455 | |
| 3upj | U03 | Gag-Pol polyprotein | / | 0.455 | |
| 4a6c | QG9 | Gag-Pol polyprotein | 3.4.23.16 | 0.455 | |
| 4loq | SB4 | Mitogen-activated protein kinase 14 | / | 0.455 | |
| 4ye3 | G04 | Gag-Pol polyprotein | 3.4.23.16 | 0.455 | |
| 1b6m | PI6 | Gag-Pol polyprotein | 3.4.23.16 | 0.454 | |
| 1ec3 | MS3 | Gag-Pol polyprotein | 3.4.23.16 | 0.454 | |
| 2bbb | HH1 | Gag-Pol polyprotein | 3.4.23.16 | 0.454 | |
| 2f8g | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.454 | |
| 2w0j | ZAT | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.454 | |
| 3ekx | 1UN | Gag-Pol polyprotein | 3.4.23.16 | 0.454 | |
| 3ndr | NAD | Pyridoxal 4-dehydrogenase | 1.1.1.107 | 0.454 | |
| 3sa7 | 55A | Protease | / | 0.454 | |
| 3tm5 | SFG | Uncharacterized protein | / | 0.454 | |
| 4iar | ERM | 5-hydroxytryptamine receptor 1B | / | 0.454 | |
| 4nju | TPV | Protease | / | 0.454 | |
| 1d4l | PI9 | Gag-Pol polyprotein | 3.4.23.16 | 0.453 | |
| 1daz | 0Q4 | Gag-Pol polyprotein | 3.4.23.16 | 0.453 | |
| 2aqu | DR7 | Gag-Pol polyprotein | 3.4.23.16 | 0.453 | |
| 2bb9 | AKC | Gag-Pol polyprotein | 3.4.23.16 | 0.453 | |
| 2ieo | 017 | Protease | / | 0.453 | |
| 2qi0 | MZ3 | Gag-Pol polyprotein | / | 0.453 | |
| 3atz | FMN | Prostaglandin F2a synthase | / | 0.453 | |
| 3el1 | DR7 | Gag-Pol polyprotein | 3.4.23.16 | 0.453 | |
| 3vt5 | YI2 | Vitamin D3 receptor | / | 0.453 | |
| 4a6b | QG8 | Gag-Pol polyprotein | 3.4.23.16 | 0.453 | |
| 4enh | FVX | Cholesterol 24-hydroxylase | / | 0.453 | |
| 4nwz | FAD | FAD-dependent pyridine nucleotide-disulfide oxidoreductase | / | 0.453 | |
| 4qgi | ROC | Gag-Pol polyprotein | 3.4.23.16 | 0.453 | |
| 4xqc | NAD | Homospermidine synthase | 2.5.1.44 | 0.453 | |
| 1d4k | PI8 | Gag-Pol polyprotein | 3.4.23.16 | 0.452 | |
| 1ec0 | BED | Gag-Pol polyprotein | 3.4.23.16 | 0.452 | |
| 1ivq | 0PX | Gag-Pol polyprotein | / | 0.452 | |
| 1k2b | 0Q4 | Gag-Pol polyprotein | 3.4.23.16 | 0.452 | |
| 1npa | 3NH | Gag-Pol polyprotein | 3.4.23.16 | 0.452 | |
| 1npw | LGZ | Gag-Pol polyprotein | 3.4.23.16 | 0.452 | |
| 1ppj | ANY | Cytochrome b | / | 0.452 | |
| 1q8u | H52 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.452 | |
| 1t7i | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.452 | |
| 2fdd | 385 | Pol protein | / | 0.452 | |
| 2hmy | SAM | Modification methylase HhaI | 2.1.1.37 | 0.452 | |
| 2w9s | TOP | Dihydrofolate reductase type 1 from Tn4003 | 1.5.1.3 | 0.452 | |
| 2zl9 | VDA | Vitamin D3 receptor | / | 0.452 | |
| 3em4 | DR7 | Gag-Pol polyprotein | 3.4.23.16 | 0.452 | |
| 3kpz | ZNE | Vitamin D3 receptor | / | 0.452 | |
| 3kyt | HC2 | Nuclear receptor ROR-gamma | / | 0.452 | |
| 4hdp | G52 | Gag-Pol polyprotein | 3.4.23.16 | 0.452 | |
| 4hla | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.452 | |
| 4j6d | TES | Cytochrome P450 monooxygenase | / | 0.452 | |
| 4l8u | 9AZ | Serum albumin | / | 0.452 | |
| 4lop | SB4 | Mitogen-activated protein kinase 14 | / | 0.452 | |
| 1a9m | U0E | Gag-Pol polyprotein | / | 0.451 | |
| 1mes | DMP | Gag-Pol polyprotein | 3.4.23.16 | 0.451 | |
| 1nzd | UPG | DNA beta-glucosyltransferase | / | 0.451 | |
| 1qbr | XV6 | Gag-Pol polyprotein | 3.4.23.16 | 0.451 | |
| 1uum | AFI | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.451 | |
| 2xye | CXG | Gag-Pol polyprotein | / | 0.451 | |
| 4cql | NAD | Estradiol 17-beta-dehydrogenase 8 | 1.1.1.62 | 0.451 | |
| 4fr4 | STU | Serine/threonine-protein kinase 32A | 2.7.11.1 | 0.451 | |
| 4k4p | 3TL | Gag-Pol polyprotein | / | 0.451 | |
| 4l9k | EHF | Serum albumin | / | 0.451 | |
| 5bp9 | SAH | Putative methyltransferase protein | / | 0.451 | |
| 7upj | INU | Gag-Pol polyprotein | 3.4.23.16 | 0.451 | |
| 2bpz | 3IN | Gag-Pol polyprotein | 3.4.23.16 | 0.450 | |
| 2q55 | MU0 | Protease | / | 0.450 | |
| 2qi1 | MZ4 | Gag-Pol polyprotein | / | 0.450 | |
| 3jw2 | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.450 | |
| 3l8s | BFF | Mitogen-activated protein kinase 14 | / | 0.450 | |
| 3pb3 | SAH | 16S rRNA (adenine(1408)-N(1))-methyltransferase | 2.1.1.180 | 0.450 | |
| 3qp0 | NI8 | Gag-Pol polyprotein | 3.4.23.16 | 0.450 | |
| 3syi | FAD | Sulfide-quinone reductase | / | 0.450 | |
| 3t3c | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.450 | |
| 3zpu | M8B | Gag-Pol polyprotein | 3.4.23.16 | 0.450 | |
| 4anv | 751 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.450 | |
| 4c4o | NAD | SADH | / | 0.450 | |
| 4dqc | 017 | Gag-Pol polyprotein | / | 0.450 | |
| 4u7t | SAH | DNA (cytosine-5)-methyltransferase 3A | 2.1.1.37 | 0.450 | |
| 4wlv | NAD | Malate dehydrogenase, mitochondrial | 1.1.1.37 | 0.450 | |
| 1c70 | L75 | Protease | / | 0.449 | |
| 1nw6 | SFG | Modification methylase RsrI | 2.1.1.72 | 0.449 | |
| 1sh9 | RIT | Gag-Pol polyprotein | 3.4.23.16 | 0.449 | |
| 2cen | 4AH | Protease | / | 0.449 | |
| 2fzw | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.449 | |
| 2q63 | 1UN | Gag-Pol polyprotein | 3.4.23.16 | 0.449 | |
| 2wyv | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.449 | |
| 3el9 | DR7 | Gag-Pol polyprotein | 3.4.23.16 | 0.449 | |
| 3em6 | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.449 | |
| 3ndu | ROC | Gag-Pol polyprotein | 3.4.23.16 | 0.449 | |
| 3o9f | K2D | Gag-Pol polyprotein | / | 0.449 | |
| 3stu | DK3 | Methylketone synthase I | / | 0.449 | |
| 3sz0 | FAD | Sulfide-quinone reductase | / | 0.449 | |
| 3t14 | FAD | Sulfide-quinone reductase | / | 0.449 | |
| 3tm4 | SAM | Uncharacterized protein | / | 0.449 | |
| 3vtd | TKD | Vitamin D3 receptor | / | 0.449 | |
| 4b4d | FAD | Ferredoxin-NADP reductase | / | 0.449 | |
| 4dqe | 017 | Gag-Pol polyprotein | / | 0.449 | |
| 4g1d | 0VK | Vitamin D3 receptor A | / | 0.449 | |
| 4g1y | 0VO | Vitamin D3 receptor A | / | 0.449 | |
| 1ahi | CHO | 7-alpha-hydroxysteroid dehydrogenase | 1.1.1.159 | 0.448 | |
| 1bai | 0Q4 | Gag-Pro polyprotein | / | 0.448 | |
| 1bve | DMP | Gag-Pol polyprotein | 3.4.23.16 | 0.448 | |
| 1c6y | MK1 | Protease | / | 0.448 | |
| 1qnf | FAD | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.448 | |
| 1sbg | IM1 | Gag-Pol polyprotein | / | 0.448 | |
| 1sdt | MK1 | Gag-Pol polyprotein | 3.4.23.16 | 0.448 | |
| 1wbk | 568 | Pol protein | / | 0.448 | |
| 1ydt | IQB | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.448 | |
| 2qi4 | MZ6 | Gag-Pol polyprotein | / | 0.448 | |
| 2wsb | NAD | Galactitol dehydrogenase | / | 0.448 | |
| 2ww4 | ADP | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | 2.7.1.148 | 0.448 | |
| 2ycr | HCW | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.448 | |
| 3aid | ARQ | Gag-Pol polyprotein | 3.4.23.16 | 0.448 | |
| 3b70 | NAP | Enoyl reductase LovC | 1 | 0.448 | |
| 3ekw | DR7 | Gag-Pol polyprotein | 3.4.23.16 | 0.448 | |
| 3kf0 | 3TL | Gag-Pol polyprotein | / | 0.448 | |
| 3kfr | 3TL | Gag-Pol polyprotein | / | 0.448 | |
| 3t2k | FAD | Sulfide-quinone reductase | / | 0.448 | |
| 3vfa | 031 | Gag-Pol polyprotein | 3.4.23.16 | 0.448 | |
| 4heg | G52 | Gag-Pol polyprotein | 3.4.23.16 | 0.448 | |
| 4nie | NBH | Nuclear receptor ROR-gamma | / | 0.448 | |
| 1ec1 | BEE | Gag-Pol polyprotein | 3.4.23.16 | 0.447 | |
| 1fgc | 2NC | Gag-Pol polyprotein | 3.4.23.16 | 0.447 | |
| 1g35 | AHF | Gag-Pol polyprotein | 3.4.23.16 | 0.447 | |
| 1izh | Q50 | Protease | / | 0.447 | |
| 1zsr | 0ZT | Gag-Pol polyprotein | 3.4.23.16 | 0.447 | |
| 2bpx | MK1 | Gag-Pol polyprotein | 3.4.23.16 | 0.447 | |
| 2fde | 385 | Gag-Pol polyprotein | 3.4.23.16 | 0.447 | |
| 2hs1 | 017 | Protease | / | 0.447 | |
| 2hs2 | 017 | Protease | / | 0.447 | |
| 2xyn | VX6 | Abelson tyrosine-protein kinase 2 | 2.7.10.2 | 0.447 | |
| 2yim | MC4 | Probable alpha-methylacyl-CoA racemase Mcr (2-methylacyl-CoA racemase) (2-arylpropionyl-CoA epimerase ) | / | 0.447 | |
| 3cbs | R12 | Cellular retinoic acid-binding protein 2 | / | 0.447 | |
| 3g6z | A7T | Renin | 3.4.23.15 | 0.447 | |
| 3i6o | GR6 | Gag-Pol polyprotein | 3.4.23.16 | 0.447 | |
| 3kq7 | KQ7 | Mitogen-activated protein kinase 14 | / | 0.447 | |
| 3kxw | 1ZZ | Saframycin Mx1 synthetase B | / | 0.447 | |
| 3mht | SAH | Modification methylase HhaI | 2.1.1.37 | 0.447 | |
| 3ndt | ROC | Gag-Pol polyprotein | 3.4.23.16 | 0.447 | |
| 3ogq | AB1 | Pol polyprotein | / | 0.447 | |
| 3uyl | TYD | Probable NDP-rhamnosyltransferase | / | 0.447 | |
| 4b5p | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.447 | |
| 4bkz | 1WS | Maternal embryonic leucine zipper kinase | 2.7.11.1 | 0.447 | |
| 4f9b | 0SY | Cell division cycle 7-related protein kinase | 2.7.11.1 | 0.447 | |
| 2avs | MK1 | Gag-Pol polyprotein | 3.4.23.16 | 0.446 | |
| 2f7x | 4EA | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.446 | |
| 2gsd | NAD | Formate dehydrogenase | / | 0.446 | |
| 2ji6 | ADP | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.446 | |
| 2nmy | ROC | Protease | / | 0.446 | |
| 2nry | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.446 | |
| 2q64 | 1UN | Gag-Pol polyprotein | 3.4.23.16 | 0.446 | |
| 2uzw | SS4 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.446 | |
| 2xiq | 5AD | Methylmalonyl-CoA mutase, mitochondrial | / | 0.446 | |
| 2znn | S44 | Peroxisome proliferator-activated receptor alpha | / | 0.446 | |
| 2ztl | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.446 | |
| 3cis | ATP | Universal stress protein Rv2623 | / | 0.446 | |
| 3iae | D7K | Benzaldehyde lyase | / | 0.446 | |
| 3nwq | 2NC | Gag-Pol polyprotein | 3.4.23.16 | 0.446 | |
| 3oy4 | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.446 | |
| 3w0j | T08 | Vitamin D3 receptor | / | 0.446 | |
| 3zps | EQM | Gag-Pol polyprotein | 3.4.23.16 | 0.446 | |
| 4hdb | G52 | Gag-Pol polyprotein | 3.4.23.16 | 0.446 | |
| 4hfr | 14M | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.446 | |
| 8mht | SAH | Modification methylase HhaI | 2.1.1.37 | 0.446 | |
| 1ec2 | BEJ | Gag-Pol polyprotein | 3.4.23.16 | 0.445 | |
| 1esv | LAR | Actin, alpha skeletal muscle | / | 0.445 | |
| 1hii | C20 | Gag-Pol polyprotein | / | 0.445 | |
| 1hvs | A77 | Gag-Pol polyprotein | / | 0.445 | |
| 1jol | FFO | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 1kzk | JE2 | Gag-Pol polyprotein | 3.4.23.16 | 0.445 | |
| 1qbt | 146 | Gag-Pol polyprotein | 3.4.23.16 | 0.445 | |
| 1skm | SAH | Modification methylase HhaI | 2.1.1.37 | 0.445 | |
| 1t7k | BH0 | Gag-Pol polyprotein | 3.4.23.16 | 0.445 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.445 | |
| 2p3a | 3TL | Pol protein | / | 0.445 | |
| 2wkz | 5AH | Gag-Pol polyprotein | / | 0.445 | |
| 3b89 | 5GP | 16S rRNA methylase | / | 0.445 | |
| 3g70 | A5T | Renin | 3.4.23.15 | 0.445 | |
| 3s85 | LK0 | Gag-Pol polyprotein | / | 0.445 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.445 | |
| 4f9m | FCM | Peroxisome proliferator-activated receptor gamma | / | 0.445 | |
| 4kvz | SAH | PtnL protein | / | 0.445 | |
| 1hvh | Q82 | Gag-Pol polyprotein | 3.4.23.16 | 0.444 | |
| 1k6v | XN2 | Gag-Pol polyprotein | 3.4.23.16 | 0.444 | |
| 2dpm | SAM | Modification methylase DpnIIA | 2.1.1.72 | 0.444 | |
| 2fhj | MFN | Formylmethanofuran--tetrahydromethanopterin formyltransferase | 2.3.1.101 | 0.444 | |
| 2gd6 | ACO | Probable alpha-methylacyl-CoA racemase Mcr (2-methylacyl-CoA racemase) (2-arylpropionyl-CoA epimerase ) | / | 0.444 | |
| 2q3k | MUW | Gag-Pol polyprotein | / | 0.444 | |
| 2qd7 | 065 | Gag-Pol polyprotein | 3.4.23.16 | 0.444 | |
| 2v16 | C47 | Renin | 3.4.23.15 | 0.444 | |
| 3bc3 | OPT | Cathepsin L1 | 3.4.22.15 | 0.444 | |
| 3fx5 | KNI | Gag-Pol polyprotein | 3.4.23.16 | 0.444 | |
| 3kdd | JZQ | Gag-Pol polyprotein | 3.4.23.16 | 0.444 | |
| 3ufn | ROC | Gag-Pol polyprotein | / | 0.444 | |
| 3v8w | 0G2 | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.444 | |
| 4ffm | ADP | Uncharacterized protein | / | 0.444 | |
| 4fw8 | NAI | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.444 | |
| 4fx9 | FAD | Coenzyme A disulfide reductase | 1.8.1.14 | 0.444 | |
| 4jv6 | 18F | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.444 | |
| 5fa8 | SAM | Ribosomal protein L11 methyltransferase, putative | / | 0.444 | |
| 1a8k | 0Q4 | Gag-Pol polyprotein | 3.4.23.16 | 0.443 | |
| 1a8p | FAD | Ferredoxin--NADP reductase | / | 0.443 | |
| 1ffi | 2NC | Gag-Pol polyprotein | 3.4.23.16 | 0.443 | |
| 1idb | 0DO | Gag-Pol polyprotein | / | 0.443 | |
| 1ie8 | KH1 | Vitamin D3 receptor | / | 0.443 | |
| 1meu | DMP | Gag-Pol polyprotein | 3.4.23.16 | 0.443 | |
| 1q8t | Y27 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.443 | |
| 1sdv | MK1 | Gag-Pol polyprotein | 3.4.23.16 | 0.443 | |
| 1tcx | IM1 | Gag-Pol polyprotein | 3.4.23.16 | 0.443 | |
| 2aoe | 0Q4 | Gag-Pol polyprotein | 3.4.23.16 | 0.443 | |
| 2f4b | EHA | Peroxisome proliferator-activated receptor gamma | / | 0.443 | |
| 2qhc | AB1 | Protease | / | 0.443 | |
| 2ycq | UPX | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.443 | |
| 3a2o | KNJ | Gag-Pol polyprotein | 3.4.23.16 | 0.443 | |
| 3cin | NAD | Myo-inositol-1-phosphate synthase-related protein | / | 0.443 | |
| 3em0 | CHD | Fatty acid-binding protein 6, ileal (gastrotropin) | / | 0.443 | |
| 3qaa | G04 | Gag-Pol polyprotein | 3.4.23.16 | 0.443 | |
| 3qbf | JHG | Gag-Pol polyprotein | 3.4.23.16 | 0.443 | |
| 3s56 | ROC | Protease | / | 0.443 | |
| 3ufs | HW6 | Nitric oxide synthase, brain | 1.14.13.39 | 0.443 | |
| 3up0 | D7S | aceDAF-12 | / | 0.443 | |
| 3zcn | ATP | Adenosine monophosphate-protein transferase SoFic | 2.7.7.n1 | 0.443 | |
| 4dl9 | NAD | S-(hydroxymethyl)glutathione dehydrogenase | / | 0.443 | |
| 4ruj | VDX | Vitamin D3 receptor A | / | 0.443 | |
| 5br4 | NAD | Lactaldehyde reductase | 1.1.1.77 | 0.443 | |
| 1d4s | TPV | Gag-Pol polyprotein | 3.4.23.16 | 0.442 | |
| 1jom | FFO | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1k1u | 0Q4 | Gag-Pol polyprotein | 3.4.23.16 | 0.442 | |
| 1w5v | BE3 | Gag-Pol polyprotein | 3.4.23.16 | 0.442 | |
| 1xha | R68 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.442 | |
| 1xjd | STU | Protein kinase C theta type | 2.7.11.13 | 0.442 | |
| 2avm | 2NC | Gag-Pol polyprotein | 3.4.23.16 | 0.442 | |
| 2bqv | A1A | Protease | / | 0.442 | |
| 2hb7 | O1C | Vitamin D3 receptor | / | 0.442 | |
| 2ojf | 4PY | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.442 | |
| 2pqz | G0G | Gag-Pol polyprotein | 3.4.23.16 | 0.442 | |
| 2qd6 | 065 | Gag-Pol polyprotein | 3.4.23.16 | 0.442 | |
| 2rbe | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.442 | |
| 2uxo | TAC | HTH-type transcriptional regulator TtgR | / | 0.442 | |
| 2yyy | NAP | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.59 | 0.442 | |
| 2zgz | GNP | Plasmid segregation protein ParM | / | 0.442 | |
| 3a1l | 2CC | Cytochrome P450 | / | 0.442 | |
| 3at4 | CCK | Casein kinase II subunit alpha | 2.7.11.1 | 0.442 | |
| 3ecg | 065 | Gag-Pol polyprotein | 3.4.23.47 | 0.442 | |
| 3i7e | DJR | Gag-Pol polyprotein | / | 0.442 | |
| 3mxe | K54 | Gag-Pol polyprotein | 3.4.23.16 | 0.442 | |
| 3vf5 | 031 | Gag-Pol polyprotein | 3.4.23.16 | 0.442 | |
| 3wmx | NAD | NAD dependent epimerase/dehydratase | / | 0.442 | |
| 4g95 | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 4j6b | PLO | Cytochrome P450 monooxygenase | / | 0.442 | |
| 4wxx | SAH | DNA (cytosine-5)-methyltransferase 1 | 2.1.1.37 | 0.442 | |
| 1h36 | R88 | Squalene--hopene cyclase | 4.2.1.129 | 0.441 | |
| 1hsg | MK1 | Gag-Pol polyprotein | / | 0.441 | |
| 1nw5 | SAM | Modification methylase RsrI | 2.1.1.72 | 0.441 | |
| 1q8w | M77 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.441 | |
| 2nru | T12 | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.441 | |
| 2qi6 | MZ8 | Gag-Pol polyprotein | / | 0.441 | |
| 2r43 | G3G | Gag-Pol polyprotein | 3.4.23.16 | 0.441 | |
| 2uzv | SS5 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.441 | |
| 2wl0 | 5AH | Gag-Pol polyprotein | / | 0.441 | |
| 2wug | HPK | 4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase | 3.7.1.17 | 0.441 | |
| 2y1o | T26 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.441 | |
| 3bxr | DRR | Gag-Pol polyprotein | 3.4.23.16 | 0.441 | |
| 3crz | FAD | Ferredoxin--NADP+ reductase | / | 0.441 | |
| 3cv9 | VDX | Vitamin D3 dihydroxylase | / | 0.441 | |
| 3etd | NDP | Glutamate dehydrogenase 1, mitochondrial | 1.4.1.3 | 0.441 | |
| 3h0a | D30 | Peroxisome proliferator-activated receptor gamma | / | 0.441 | |
| 3kpk | FAD | Sulfide-quinone reductase | / | 0.441 | |
| 3o9a | K14 | Pol polyprotein | / | 0.441 | |
| 3o9d | K19 | Pol polyprotein | / | 0.441 | |
| 3pt9 | SAH | DNA (cytosine-5)-methyltransferase 1 | 2.1.1.37 | 0.441 | |
| 3qrw | NDP | Putative ketoacyl reductase | 1.3.1 | 0.441 | |
| 3upk | UD1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.441 | |
| 3vt7 | VDX | Vitamin D3 receptor | / | 0.441 | |
| 3w5p | 4OA | Vitamin D3 receptor | / | 0.441 | |
| 4gbe | SAH | DNA adenine methylase | 2.1.1.72 | 0.441 | |
| 4j5j | 478 | Gag-Pol polyprotein | 3.4.23.16 | 0.441 | |
| 4lcf | 1WL | UDP-3-O-acyl-N-acetylglucosamine deacetylase | / | 0.441 | |
| 4xgu | ADP | Putative pachytene checkpoint protein 2 | / | 0.441 | |
| 5k2b | ZMA | Adenosine receptor A2a | / | 0.441 | |
| 1boo | SAH | Modification methylase PvuII | 2.1.1.113 | 0.440 | |
| 1eby | BEB | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
| 1fej | 2NC | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
| 1kzj | CB3 | Thymidylate synthase | / | 0.440 | |
| 1pro | A88 | Gag-Pol polyprotein | / | 0.440 | |
| 1tsx | UMP | Thymidylate synthase | / | 0.440 | |
| 2a4f | AAU | V-1 protease | / | 0.440 | |
| 2c7x | NRB | Cytochrome P450 monooxygenase PikC | / | 0.440 | |
| 2dvl | FAD | Acyl-CoA dehydrogenase | / | 0.440 | |
| 2ivp | ATP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.440 | |
| 2jn3 | JN3 | Fatty acid-binding protein, liver | / | 0.440 | |
| 2ore | SAH | DNA adenine methylase | 2.1.1.72 | 0.440 | |
| 2pk5 | 075 | Protease | / | 0.440 | |
| 2x3n | FAD | Probable FAD-dependent monooxygenase | / | 0.440 | |
| 2yit | YIT | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.440 | |
| 3b6z | CO7 | Enoyl reductase LovC | 1 | 0.440 | |
| 3bgb | LJG | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
| 3cbl | STU | Tyrosine-protein kinase Fes/Fps | 2.7.10.2 | 0.440 | |
| 3gy0 | NAP | NAD(P)-dependent oxidoreductase | / | 0.440 | |
| 3mdm | FJZ | Cholesterol 24-hydroxylase | / | 0.440 | |
| 3o96 | IQO | RAC-alpha serine/threonine-protein kinase | 2.7.11.1 | 0.440 | |
| 3p9k | SAH | Caffeic acid O-methyltransferase | / | 0.440 | |
| 3sa5 | A69 | Protease | / | 0.440 | |
| 3sa9 | A68 | Protease | / | 0.440 | |
| 3uhl | 2NC | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
| 4anu | EM7 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.440 | |
| 4dqf | 017 | Gag-Pol polyprotein | / | 0.440 | |
| 4e2b | FMN | Dehydrogenase | / | 0.440 | |
| 4v2g | ITC | Tetracycline repressor protein class D | / | 0.440 | |
| 4x2q | NAD | Retinal dehydrogenase 2 | 1.2.1.36 | 0.440 | |
| 5itz | LOC | Tubulin beta-2B chain | / | 0.440 |