sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1rm8 | BAT | Matrix metalloproteinase-16 | 3.4.24 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 1rm8 | BAT | Matrix metalloproteinase-16 | 3.4.24 | 1.000 | |
| 4dpe | NGH | Stromelysin-1 | 3.4.24.17 | 0.627 | |
| 2woa | 023 | Macrophage metalloelastase | 3.4.24.65 | 0.622 | |
| 3ljg | EEF | Macrophage metalloelastase | 3.4.24.65 | 0.620 | |
| 1bzs | BSI | Neutrophil collagenase | 3.4.24.34 | 0.619 | |
| 4ja1 | NGH | Stromelysin-1 | 3.4.24.17 | 0.619 | |
| 2oxw | ILE_ALA_GLY | Macrophage metalloelastase | 3.4.24.65 | 0.616 | |
| 4g9l | NGH | Stromelysin-1 | 3.4.24.17 | 0.615 | |
| 3hy7 | 097 | A disintegrin and metalloproteinase with thrombospondin motifs 5 | 3.4.24 | 0.612 | |
| 2wo8 | 077 | Macrophage metalloelastase | 3.4.24.65 | 0.609 | |
| 1biw | S80 | Stromelysin-1 | 3.4.24.17 | 0.604 | |
| 1g05 | BBH | Stromelysin-1 | 3.4.24.17 | 0.603 | |
| 2oy2 | ILE_ALA_GLY | Neutrophil collagenase | 3.4.24.34 | 0.599 | |
| 1zvx | FIN | Neutrophil collagenase | 3.4.24.34 | 0.590 | |
| 1hv5 | RXP | Stromelysin-3 | 3.4.24 | 0.586 | |
| 3oho | Z79 | Stromelysin-1 | 3.4.24.17 | 0.583 | |
| 4gr3 | R45 | Macrophage metalloelastase | 3.4.24.65 | 0.583 | |
| 2wo8 | 023 | Macrophage metalloelastase | 3.4.24.65 | 0.582 | |
| 1d7x | SPC | Stromelysin-1 | 3.4.24.17 | 0.579 | |
| 1gkc | NFH | Matrix metalloproteinase-9 | 3.4.24.35 | 0.578 | |
| 1mnc | PLH | Neutrophil collagenase | 3.4.24.34 | 0.573 | |
| 1sln | INH | Stromelysin-1 | 3.4.24.17 | 0.573 | |
| 1zs0 | EIN | Neutrophil collagenase | 3.4.24.34 | 0.573 | |
| 2wo9 | 023 | Macrophage metalloelastase | 3.4.24.65 | 0.570 | |
| 4gr8 | R4C | Macrophage metalloelastase | 3.4.24.65 | 0.567 | |
| 1g4k | HQQ | Stromelysin-1 | 3.4.24.17 | 0.564 | |
| 3hy9 | 098 | A disintegrin and metalloproteinase with thrombospondin motifs 5 | 3.4.24 | 0.562 | |
| 3zxh | E41 | Collagenase 3 | 3.4.24 | 0.560 | |
| 3b8z | 294 | A disintegrin and metalloproteinase with thrombospondin motifs 5 | 3.4.24 | 0.559 | |
| 1b8y | IN7 | Stromelysin-1 | 3.4.24.17 | 0.557 | |
| 2d1o | FA4 | Stromelysin-1 | 3.4.24.17 | 0.557 | |
| 2w0d | CGS | Macrophage metalloelastase | 3.4.24.65 | 0.556 | |
| 3le9 | 727 | Disintegrin and metalloproteinase domain-containing protein 17 | 3.4.24.86 | 0.553 | |
| 1b3d | S27 | Stromelysin-1 | 3.4.24.17 | 0.550 | |
| 2wo9 | 068 | Macrophage metalloelastase | 3.4.24.65 | 0.550 | |
| 2i47 | KGY | Disintegrin and metalloproteinase domain-containing protein 17 | 3.4.24.86 | 0.547 | |
| 2xs3 | ALA_PHE_THR_SER | Karilysin | 3.4.24 | 0.546 | |
| 2d1n | FA4 | Collagenase 3 | 3.4.24 | 0.545 | |
| 4guy | KLJ | Macrophage metalloelastase | 3.4.24.65 | 0.544 | |
| 1g49 | 111 | Stromelysin-1 | 3.4.24.17 | 0.541 | |
| 1utt | CP8 | Macrophage metalloelastase | 3.4.24.65 | 0.541 | |
| 3aig | 0ZC | Snake venom metalloproteinase adamalysin-2 | 3.4.24.46 | 0.541 | |
| 3i7g | 732 | Collagenase 3 | 3.4.24 | 0.541 | |
| 4h76 | 10B | Macrophage metalloelastase | 3.4.24.65 | 0.541 | |
| 1hy7 | MBS | Stromelysin-1 | 3.4.24.17 | 0.540 | |
| 2ovx | 4MR | Matrix metalloproteinase-9 | 3.4.24.35 | 0.539 | |
| 1atl | 0QI | Snake venom metalloproteinase atrolysin-D | 3.4.24.42 | 0.538 | |
| 2dw0 | GM6 | Zinc metalloproteinase-disintegrin-like VAP2B | 3.4.24 | 0.538 | |
| 4a7b | 3W4 | Collagenase 3 | 3.4.24 | 0.537 | |
| 1d8f | SPI | Stromelysin-1 | 3.4.24.17 | 0.536 | |
| 2xs4 | ALA_PHE_THR | Karilysin | 3.4.24 | 0.536 | |
| 1bqo | N25 | Stromelysin-1 | 3.4.24.17 | 0.534 | |
| 2ovz | 5MR | Matrix metalloproteinase-9 | 3.4.24.35 | 0.533 | |
| 2jih | 097 | A disintegrin and metalloproteinase with thrombospondin motifs 1 | 3.4.24 | 0.529 | |
| 3kmc | 403 | Disintegrin and metalloproteinase domain-containing protein 17 | 3.4.24.86 | 0.528 | |
| 3kme | INN | Disintegrin and metalloproteinase domain-containing protein 17 | 3.4.24.86 | 0.528 | |
| 1d5j | MM3 | Stromelysin-1 | 3.4.24.17 | 0.526 | |
| 2ow0 | 6MR | Matrix metalloproteinase-9 | 3.4.24.35 | 0.526 | |
| 3b92 | 440 | Disintegrin and metalloproteinase domain-containing protein 17 | 3.4.24.86 | 0.526 | |
| 1dth | BAT | Snake venom metalloproteinase atrolysin-D | 3.4.24.42 | 0.522 | |
| 1d8m | BBH | Stromelysin-1 | 3.4.24.17 | 0.520 | |
| 1jk3 | BAT | Macrophage metalloelastase | 3.4.24.65 | 0.520 | |
| 4i03 | L88 | Macrophage metalloelastase | 3.4.24.65 | 0.519 | |
| 1zxc | IH6 | Disintegrin and metalloproteinase domain-containing protein 17 | 3.4.24.86 | 0.515 | |
| 2a8h | 4NH | Disintegrin and metalloproteinase domain-containing protein 17 | 3.4.24.86 | 0.514 | |
| 2i47 | INN | Disintegrin and metalloproteinase domain-containing protein 17 | 3.4.24.86 | 0.512 | |
| 3l0t | INN | Disintegrin and metalloproteinase domain-containing protein 17 | 3.4.24.86 | 0.512 | |
| 3ayk | CGS | Interstitial collagenase | 3.4.24.7 | 0.508 | |
| 2ow1 | 7MR | Matrix metalloproteinase-9 | 3.4.24.35 | 0.502 | |
| 3lgp | 50X | Disintegrin and metalloproteinase domain-containing protein 17 | 3.4.24.86 | 0.502 | |
| 4ayk | CGS | Interstitial collagenase | 3.4.24.7 | 0.501 | |
| 1fm1 | WAY | Collagenase 3 | 3.4.24 | 0.498 | |
| 2w13 | WR2 | Snake venom metalloproteinase BaP1 | 3.4.24 | 0.489 | |
| 1fls | WAY | Collagenase 3 | 3.4.24 | 0.487 | |
| 2srt | INH | Stromelysin-1 | 3.4.24.17 | 0.487 | |
| 1xur | PB5 | Collagenase 3 | 3.4.24 | 0.485 | |
| 1x1c | SAH | C-20 methyltransferase | / | 0.484 | |
| 4qen | SAH | Histone-lysine N-methyltransferase, H3 lysine-9 specific SUVH4 | 2.1.1.43 | 0.484 | |
| 1i7p | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.481 | |
| 1m9n | AMZ | Bifunctional purine biosynthesis protein PURH | 2.1.2.3 | 0.481 | |
| 2g1y | 5IG | Renin | 3.4.23.15 | 0.481 | |
| 2jnp | NGH | Stromelysin-1 | 3.4.24.17 | 0.481 | |
| 3ljt | LA3 | A disintegrin and metalloproteinase with thrombospondin motifs 5 | 3.4.24 | 0.478 | |
| 4bf9 | FMN | tRNA-dihydrouridine(16) synthase | / | 0.477 | |
| 1c8t | TR1 | Stromelysin-1 | 3.4.24.17 | 0.476 | |
| 1fm7 | DFV | Chalcone--flavonone isomerase 1 | 5.5.1.6 | 0.476 | |
| 2xlr | FAD | Putative flavin-containing monooxygenase | / | 0.475 | |
| 2xq0 | BES | Leukotriene A-4 hydrolase homolog | 3.3.2.6 | 0.475 | |
| 3djj | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.475 | |
| 3zdu | 38R | Cyclin-dependent kinase-like 3 | 2.7.11.22 | 0.474 | |
| 3l0v | 724 | Disintegrin and metalloproteinase domain-containing protein 17 | 3.4.24.86 | 0.473 | |
| 3p67 | FMN | Pentaerythritol tetranitrate reductase | / | 0.473 | |
| 2gjn | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.471 | |
| 3u04 | BB2 | Peptide deformylase | / | 0.471 | |
| 4m49 | 22Y | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.471 | |
| 4yco | FMN | tRNA-dihydrouridine(16) synthase | / | 0.471 | |
| 1sve | I01 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.470 | |
| 3img | BZ3 | Pantothenate synthetase | 6.3.2.1 | 0.470 | |
| 4ycp | FMN | tRNA-dihydrouridine(16) synthase | / | 0.470 | |
| 3br3 | ET | HTH-type transcriptional regulator QacR | / | 0.469 | |
| 5ewj | QEL | NMDA glutamate receptor subunit | / | 0.469 | |
| 5ewj | QEL | Glutamate receptor ionotropic, NMDA 2B | / | 0.469 | |
| 2jsd | NGH | Matrix metalloproteinase-20 | 3.4.24 | 0.468 | |
| 1r6t | TYM | Tryptophan--tRNA ligase, cytoplasmic | 6.1.1.2 | 0.467 | |
| 3ioe | A7D | Pantothenate synthetase | 6.3.2.1 | 0.467 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.466 | |
| 2yq9 | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.466 | |
| 3sj7 | NDP | 3-oxoacyl-(Acyl-carrier-protein) reductase, putative | / | 0.466 | |
| 3lqs | PSZ | D-alanine aminotransferase | 2.6.1.21 | 0.465 | |
| 3m6p | BB2 | Peptide deformylase 1B, chloroplastic/mitochondrial | 3.5.1.88 | 0.465 | |
| 5egh | PC | Ectonucleotide pyrophosphatase/phosphodiesterase family member 6 | / | 0.465 | |
| 2e15 | SAH | Diphthine synthase | / | 0.464 | |
| 3o03 | NAP | Dehydrogenase with different specificities (Related to short-chain alcohol dehydrogenase) | / | 0.464 | |
| 1gc5 | ADP | ADP-dependent glucokinase | 2.7.1.147 | 0.463 | |
| 2y6d | TQJ | Matrilysin | 3.4.24.23 | 0.463 | |
| 4b66 | NAP | L-ornithine N(5)-monooxygenase | / | 0.463 | |
| 1itz | TPP | Transketolase, chloroplastic | 2.2.1.1 | 0.462 | |
| 1g1a | NAD | dTDP-glucose 4,6-dehydratase | / | 0.461 | |
| 2hxz | H7J | Cathepsin S | 3.4.22.27 | 0.461 | |
| 3ha5 | SFG | Hydroxymycolate synthase MmaA4 | 2.1.1 | 0.461 | |
| 3uyt | 0CK | Casein kinase I isoform delta | 2.7.11.1 | 0.460 | |
| 4egb | NAD | dTDP-glucose 4,6-dehydratase | / | 0.460 | |
| 1h60 | STR | Pentaerythritol tetranitrate reductase | / | 0.459 | |
| 2vhw | NAI | Alanine dehydrogenase | 1.4.1.1 | 0.459 | |
| 4eph | 0RK | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.459 | |
| 5ar4 | SB2 | Receptor-interacting serine/threonine-protein kinase 2 | 2.7.11.1 | 0.459 | |
| 1pwu | GM6 | Lethal factor | 3.4.24.83 | 0.458 | |
| 1tqf | 32P | Beta-secretase 1 | 3.4.23.46 | 0.458 | |
| 2r6g | ATP | Maltose/maltodextrin import ATP-binding protein MalK | / | 0.458 | |
| 3inv | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.458 | |
| 1ps9 | MDE | 2,4-dienoyl-CoA reductase | 1.3.1.34 | 0.457 | |
| 1vyr | FMN | Pentaerythritol tetranitrate reductase | / | 0.457 | |
| 2owu | SAH | Diphthine synthase | / | 0.457 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.457 | |
| 5c8w | PCG | cGMP-dependent protein kinase 2 | 2.7.11.12 | 0.457 | |
| 1uay | ADN | Oxidoreductase | / | 0.456 | |
| 2cnd | FAD | Nitrate reductase [NADH] | 1.7.1.1 | 0.456 | |
| 4kgm | ATP | Uncharacterized protein | / | 0.456 | |
| 1bwl | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.455 | |
| 1x7d | NAD | Putative ornithine cyclodeaminase | / | 0.455 | |
| 1zdf | UPG | Glycogenin-1 | 2.4.1.186 | 0.455 | |
| 2a94 | AP0 | L-lactate dehydrogenase | 1.1.1.27 | 0.455 | |
| 2znp | K55 | Peroxisome proliferator-activated receptor delta | / | 0.455 | |
| 3c8b | ARG_ARG_GLY_ILE_NH2 | Botulinum neurotoxin type A | 3.4.24.69 | 0.455 | |
| 3ime | BZ2 | Pantothenate synthetase | 6.3.2.1 | 0.455 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.455 | |
| 4avl | TMP | Polymerase acidic protein | / | 0.455 | |
| 4ynp | SAM | Histone-lysine N-methyltransferase ASH1L | 2.1.1.43 | 0.455 | |
| 5cnn | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.455 | |
| 1h51 | FMN | Pentaerythritol tetranitrate reductase | / | 0.454 | |
| 1ol6 | ATP | Aurora kinase A | 2.7.11.1 | 0.454 | |
| 1phe | PIY | Camphor 5-monooxygenase | 1.14.15.1 | 0.454 | |
| 2g28 | TDK | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.454 | |
| 3dga | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.454 | |
| 3ftx | BES | Leukotriene A-4 hydrolase | 3.3.2.6 | 0.454 | |
| 4opg | FDA | Conserved Archaeal protein | / | 0.454 | |
| 1rp0 | AHZ | Thiamine thiazole synthase, chloroplastic | / | 0.453 | |
| 1ws1 | BB2 | Peptide deformylase 1 | / | 0.453 | |
| 2pch | SAH | Diphthine synthase | / | 0.453 | |
| 2v3o | I26 | Prothrombin | 3.4.21.5 | 0.453 | |
| 1gpd | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.452 | |
| 2z2d | HSI | Macrophage metalloelastase | 3.4.24.65 | 0.452 | |
| 3cuk | FAD | D-amino-acid oxidase | 1.4.3.3 | 0.452 | |
| 3kek | 3EK | Collagenase 3 | 3.4.24 | 0.452 | |
| 3koz | Z97 | D-ornithine 4,5-aminomutase subunit beta | / | 0.452 | |
| 4bby | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.452 | |
| 1cnf | FAD | Nitrate reductase [NADH] | 1.7.1.1 | 0.451 | |
| 1h63 | FMN | Pentaerythritol tetranitrate reductase | / | 0.451 | |
| 2g1r | 3IG | Renin | 3.4.23.15 | 0.451 | |
| 2ow2 | 8MR | Matrix metalloproteinase-9 | 3.4.24.35 | 0.451 | |
| 3gdp | FAD | (R)-mandelonitrile lyase 2 | 4.1.2.10 | 0.451 | |
| 3otw | COA | Phosphopantetheine adenylyltransferase | / | 0.451 | |
| 3pdq | KC6 | Lysine-specific demethylase 4A | 1.14.11 | 0.451 | |
| 3qlr | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 4k81 | GTP | GTPase HRas | / | 0.451 | |
| 1ma0 | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.450 | |
| 1q3a | NGH | Stromelysin-2 | 3.4.24.22 | 0.450 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.450 | |
| 3hyg | 099 | A disintegrin and metalloproteinase with thrombospondin motifs 5 | 3.4.24 | 0.450 | |
| 3kjr | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.450 | |
| 3q9t | FAY | Uncharacterized protein | / | 0.450 | |
| 4df2 | FMN | NADPH dehydrogenase | / | 0.450 | |
| 4ef9 | FMN | Dihydroorotate dehydrogenase (fumarate) | / | 0.450 | |
| 1icp | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.449 | |
| 2jla | TPP | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.449 | |
| 2qbm | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.449 | |
| 4fcd | 0T6 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.449 | |
| 2eeq | SAH | Diphthine synthase | / | 0.448 | |
| 2i4q | UA4 | Renin | 3.4.23.15 | 0.448 | |
| 2p6k | SAH | Diphthine synthase | / | 0.448 | |
| 2zdy | ADP | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial | 2.7.11.2 | 0.448 | |
| 3afh | GSU | Glutamate--tRNA ligase 2 | / | 0.448 | |
| 3aut | NAI | Glucose 1-dehydrogenase 4 | 1.1.1.47 | 0.448 | |
| 3fuh | BES | Leukotriene A-4 hydrolase | 3.3.2.6 | 0.448 | |
| 3qiy | QI1 | Botulinum neurotoxin type A | 3.4.24.69 | 0.448 | |
| 5ej8 | TD6 | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.448 | |
| 1ep1 | FMN | Dihydroorotate dehydrogenase B (NAD(+)), catalytic subunit | 1.3.1.14 | 0.447 | |
| 2qfo | A51 | Heat shock protein HSP 90-alpha | / | 0.447 | |
| 2x3f | APC | Pantothenate synthetase | / | 0.447 | |
| 2yj5 | ATP | Copper-transporting ATPase | / | 0.447 | |
| 3ebi | BEY | M1 family aminopeptidase | 3.4.11 | 0.447 | |
| 4drm | 0MC | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.447 | |
| 4nd3 | NAD | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.447 | |
| 4yqf | GDP | Septin-9 | / | 0.447 | |
| 1sb1 | 165 | Prothrombin | 3.4.21.5 | 0.446 | |
| 2a0y | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.446 | |
| 2cft | PLP | Pyridoxal phosphate phosphatase | / | 0.446 | |
| 2ejj | SAH | Diphthine synthase | / | 0.446 | |
| 3c8a | ARG_ARG_GLY_LEU_NH2 | Botulinum neurotoxin type A | 3.4.24.69 | 0.446 | |
| 3e2s | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.446 | |
| 3f28 | S7B | Thermolysin | 3.4.24.27 | 0.446 | |
| 3ivx | FG6 | Pantothenate synthetase | 6.3.2.1 | 0.446 | |
| 3lik | EEG | Macrophage metalloelastase | 3.4.24.65 | 0.446 | |
| 3ts1 | TYA | Tyrosine--tRNA ligase | 6.1.1.1 | 0.446 | |
| 4dc0 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.446 | |
| 4j36 | 1HR | Kynurenine 3-monooxygenase | / | 0.446 | |
| 4prx | ADP | DNA gyrase subunit B | / | 0.446 | |
| 4zse | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.446 | |
| 5es7 | FON | Linear gramicidin synthase subunit A | / | 0.446 | |
| 7std | CRP | Scytalone dehydratase | 4.2.1.94 | 0.446 | |
| 1qyx | ASD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.445 | |
| 1rx1 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 1uda | UFG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.445 | |
| 2abb | FMN | Pentaerythritol tetranitrate reductase | / | 0.445 | |
| 2cv2 | GSU | Glutamate--tRNA ligase | 6.1.1.17 | 0.445 | |
| 2e8h | SAH | Diphthine synthase | / | 0.445 | |
| 2fe4 | GDP | Ras-related protein Rab-6B | / | 0.445 | |
| 2iko | 7IG | Renin | 3.4.23.15 | 0.445 | |
| 2il2 | LIX | Renin | 3.4.23.15 | 0.445 | |
| 3ivg | FG5 | Pantothenate synthetase | 6.3.2.1 | 0.445 | |
| 3q43 | D66 | M1 family aminopeptidase | 3.4.11 | 0.445 | |
| 3s87 | ADP | Ribonucleoside-diphosphate reductase large chain 1 | 1.17.4.1 | 0.445 | |
| 3uk6 | ADP | RuvB-like 2 | 3.6.4.12 | 0.445 | |
| 4ejm | NAP | Putative zinc-binding dehydrogenase | / | 0.445 | |
| 5cyo | GDP | Septin-9 | / | 0.445 | |
| 1ivs | VAA | Valine--tRNA ligase | 6.1.1.9 | 0.444 | |
| 1jqd | SAH | Histamine N-methyltransferase | 2.1.1.8 | 0.444 | |
| 1t86 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.444 | |
| 2b03 | TUD | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.444 | |
| 2f3r | G5P | Guanylate kinase | 2.7.4.8 | 0.444 | |
| 2j9f | THV | 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial | 1.2.4.4 | 0.444 | |
| 2j9f | THV | 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial | 1.2.4.4 | 0.444 | |
| 2pja | 33Z | Carboxypeptidase B | / | 0.444 | |
| 2xve | FAD | Putative flavin-containing monooxygenase | / | 0.444 | |
| 4jic | FMN | GTN Reductase | / | 0.444 | |
| 4mvc | CDC | Choline-phosphate cytidylyltransferase A | / | 0.444 | |
| 4s26 | SAH | Phosphomethylpyrimidine synthase, chloroplastic | 4.1.99.17 | 0.444 | |
| 4yxs | EMU | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.444 | |
| 2anm | CDO | Prothrombin | 3.4.21.5 | 0.443 | |
| 2djl | FMN | Dihydroorotate dehydrogenase (fumarate) | 1.3.98.1 | 0.443 | |
| 3ens | ENS | Coagulation factor X | 3.4.21.6 | 0.443 | |
| 5eja | TD6 | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.443 | |
| 1h50 | FMN | Pentaerythritol tetranitrate reductase | / | 0.442 | |
| 1q5m | NDP | Prostaglandin-E(2) 9-reductase | 1.1.1.189 | 0.442 | |
| 2fgj | ATP | Alpha-hemolysin translocation ATP-binding protein HlyB | / | 0.442 | |
| 2o1s | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.442 | |
| 2q1u | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.442 | |
| 2wed | PP6 | Penicillopepsin-1 | 3.4.23.20 | 0.442 | |
| 2zfr | 46U | Prothrombin | 3.4.21.5 | 0.442 | |
| 3bgx | MEF | Thymidylate synthase | / | 0.442 | |
| 3ehe | NAD | UDP-glucose 4-epimerase (GalE-1) | / | 0.442 | |
| 3fd6 | ADP | Selenide, water dikinase 1 | 2.7.9.3 | 0.442 | |
| 3muo | ZPR | Prolyl endopeptidase | / | 0.442 | |
| 3pm1 | ET | HTH-type transcriptional regulator QacR | / | 0.442 | |
| 3zho | FMN | NAD(P)H dehydrogenase (quinone) | / | 0.442 | |
| 4aux | XTC | Tetracycline repressor protein class D | / | 0.442 | |
| 4ih6 | 1EP | Genome polyprotein | 2.7.7.48 | 0.442 | |
| 4oae | CLM | Uncharacterized protein | / | 0.442 | |
| 1e7q | NAP | GDP-L-fucose synthase | / | 0.441 | |
| 1jtv | TES | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.441 | |
| 1x1b | SAH | C-20 methyltransferase | / | 0.441 | |
| 1x1d | SAH | C-20 methyltransferase | / | 0.441 | |
| 1zxn | ADP | DNA topoisomerase 2-alpha | 5.99.1.3 | 0.441 | |
| 2e9u | A25 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.441 | |
| 2egs | SAH | Diphthine synthase | / | 0.441 | |
| 2ej2 | PPE | Branched-chain amino acid aminotransferase (IlvE) | / | 0.441 | |
| 2jdt | I5S | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.441 | |
| 2r5n | TPP | Transketolase 1 | / | 0.441 | |
| 2rlc | CHD | Choloylglycine hydrolase | 3.5.1.24 | 0.441 | |
| 2vwq | NAP | Glucose 1-dehydrogenase | / | 0.441 | |
| 2web | PP4 | Penicillopepsin-1 | 3.4.23.20 | 0.441 | |
| 3wrj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.441 | |
| 4ge9 | 0L0 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.441 | |
| 4s1i | PLP | Pyridoxal kinase, putative | / | 0.441 | |
| 5jr3 | SAH | Carminomycin 4-O-methyltransferase DnrK | 2.1.1.292 | 0.441 | |
| 1eio | GCH | Gastrotropin | / | 0.440 | |
| 1nbi | SAM | Glycine N-methyltransferase | 2.1.1.20 | 0.440 | |
| 1nj6 | A5A | Proline--tRNA ligase | / | 0.440 | |
| 2g7y | MO9 | Cathepsin S | 3.4.22.27 | 0.440 | |
| 2o7o | DXT | Tetracycline repressor protein class D | / | 0.440 | |
| 2p2x | SAH | Diphthine synthase | / | 0.440 | |
| 2vcj | 2EQ | Heat shock protein HSP 90-alpha | / | 0.440 | |
| 2z71 | PNV | Penicillin acylase | 3.5.1.11 | 0.440 | |
| 2znq | 401 | Peroxisome proliferator-activated receptor delta | / | 0.440 | |
| 3fql | 79Z | Genome polyprotein | 2.7.7.48 | 0.440 | |
| 3ig6 | 438 | Urokinase-type plasminogen activator | 3.4.21.73 | 0.440 | |
| 3lxp | IZA | Non-receptor tyrosine-protein kinase TYK2 | 2.7.10.2 | 0.440 | |
| 3ow3 | SMY | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.440 | |
| 3zhs | TD6 | Multifunctional 2-oxoglutarate metabolism enzyme | 1.2.4.2 | 0.440 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.440 | |
| 4e31 | JHZ | Methyltransferase | / | 0.440 | |
| 4j57 | FAD | Thioredoxin reductase 2 | 1.8.1.9 | 0.440 | |
| 4kby | C2E | Stimulator of interferon genes protein | / | 0.440 | |
| 4oh4 | ANP | Protein BRASSINOSTEROID INSENSITIVE 1 | 2.7.10.1 | 0.440 | |
| 5ej6 | TD6 | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.440 | |
| 5esd | TDP | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.440 |