sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1pwm | FID | Aldose reductase | 1.1.1.21 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 1pwm | FID | Aldose reductase | 1.1.1.21 | 1.000 | |
| 2pdy | FID | Aldose reductase | 1.1.1.21 | 0.785 | |
| 2pdw | FID | Aldose reductase | 1.1.1.21 | 0.771 | |
| 2is7 | 2CL | Aldose reductase | 1.1.1.21 | 0.690 | |
| 1ef3 | FID | Aldose reductase | 1.1.1.21 | 0.643 | |
| 3s3g | TLT | Aldose reductase | 1.1.1.21 | 0.619 | |
| 3u2c | SUZ | Aldose reductase | 1.1.1.21 | 0.614 | |
| 4gab | FID | Aldo-keto reductase family 1 member B10 | 1.1.1 | 0.612 | |
| 2f2k | TGG | Aldose reductase | 1.1.1.21 | 0.610 | |
| 2pd9 | FID | Aldose reductase | 1.1.1.21 | 0.607 | |
| 2inz | OHP | Aldose reductase | 1.1.1.21 | 0.604 | |
| 2nvc | ITA | Aldose reductase | 1.1.1.21 | 0.581 | |
| 2pdk | SBI | Aldose reductase | 1.1.1.21 | 0.575 | |
| 2pdm | ZST | Aldose reductase | 1.1.1.21 | 0.571 | |
| 3p2v | DOY | Aldose reductase | 1.1.1.21 | 0.570 | |
| 1eko | I84 | Aldose reductase | 1.1.1.21 | 0.563 | |
| 1ah0 | SBI | Aldose reductase | 1.1.1.21 | 0.560 | |
| 3v35 | NTI | Aldose reductase | 1.1.1.21 | 0.555 | |
| 1el3 | I84 | Aldose reductase | 1.1.1.21 | 0.539 | |
| 2hvo | ZST | Aldose reductase | 1.1.1.21 | 0.530 | |
| 5liu | 388 | Aldo-keto reductase family 1 member B10 | 1.1.1 | 0.525 | |
| 2agt | FID | Aldose reductase | 1.1.1.21 | 0.524 | |
| 2pdf | ZST | Aldose reductase | 1.1.1.21 | 0.524 | |
| 2pdj | 393 | Aldose reductase | 1.1.1.21 | 0.524 | |
| 1az1 | ALR | Aldose reductase | 1.1.1.21 | 0.513 | |
| 2duz | ZST | Aldose reductase | 1.1.1.21 | 0.512 | |
| 2hvn | ZST | Aldose reductase | 1.1.1.21 | 0.505 | |
| 1uho | VDN | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.504 | |
| 4g2w | NI0 | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.504 | |
| 2f38 | 15M | Aldo-keto reductase family 1 member C3 | / | 0.496 | |
| 2ikj | 393 | Aldose reductase | 1.1.1.21 | 0.494 | |
| 3bv7 | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.494 | |
| 2pdu | 393 | Aldose reductase | 1.1.1.21 | 0.493 | |
| 1oyn | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.490 | |
| 1ry0 | PG2 | Aldo-keto reductase family 1 member C3 | / | 0.490 | |
| 2i16 | LDT | Aldose reductase | 1.1.1.21 | 0.487 | |
| 4kfj | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.487 | |
| 4dbu | BT9 | Aldo-keto reductase family 1 member C3 | / | 0.486 | |
| 1s3u | TQD | Dihydrofolate reductase | 1.5.1.3 | 0.485 | |
| 4a95 | 9MT | Glycylpeptide N-tetradecanoyltransferase | / | 0.483 | |
| 1mvt | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.482 | |
| 1us0 | LDT | Aldose reductase | 1.1.1.21 | 0.480 | |
| 2dhf | DZF | Dihydrofolate reductase | 1.5.1.3 | 0.479 | |
| 1hfr | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.478 | |
| 3h4g | FID | Alcohol dehydrogenase [NADP(+)] | 1.1.1.2 | 0.478 | |
| 2yne | YNE | Glycylpeptide N-tetradecanoyltransferase | / | 0.477 | |
| 3u5y | SCG | Raucaffricine-O-beta-D-glucosidase | 3.2.1.125 | 0.477 | |
| 4bbh | YBN | Glycylpeptide N-tetradecanoyltransferase | / | 0.477 | |
| 2pdh | 47D | Aldose reductase | 1.1.1.21 | 0.476 | |
| 4b11 | 7I1 | Glycylpeptide N-tetradecanoyltransferase | / | 0.475 | |
| 2jl1 | NAP | Triphenylmethane reductase | / | 0.474 | |
| 1e1f | PSG | 4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase 1, chloroplastic | 3.2.1.182 | 0.473 | |
| 1ry8 | RUT | Aldo-keto reductase family 1 member C3 | / | 0.472 | |
| 1xor | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.472 | |
| 4b13 | X25 | Glycylpeptide N-tetradecanoyltransferase | / | 0.472 | |
| 4b14 | 4XB | Glycylpeptide N-tetradecanoyltransferase | / | 0.472 | |
| 4wev | SUZ | Aldo-keto reductase family 1 member B10 | 1.1.1 | 0.472 | |
| 2bjs | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.471 | |
| 2hzq | STR | Apolipoprotein D | / | 0.471 | |
| 4g2y | NI5 | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.471 | |
| 4gv4 | MEJ | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.471 | |
| 1rxj | BNI | Streptavidin | / | 0.470 | |
| 3g5e | Q74 | Aldose reductase | 1.1.1.21 | 0.470 | |
| 4m6k | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.470 | |
| 1u70 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.469 | |
| 2c9z | QUE | Anthocyanidin 3-O-glucosyltransferase 2 | 2.4.1.115 | 0.469 | |
| 3wav | DWV | Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 | 3.1.4.39 | 0.468 | |
| 4oex | 5EO | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.468 | |
| 4fam | 0SZ | Aldo-keto reductase family 1 member C3 | / | 0.467 | |
| 2w3m | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.466 | |
| 3ugr | IMN | Aldo-keto reductase family 1 member C3 | / | 0.466 | |
| 4dbw | 511 | Aldo-keto reductase family 1 member C3 | / | 0.466 | |
| 1ohj | COP | Dihydrofolate reductase | 1.5.1.3 | 0.465 | |
| 1sg0 | STL | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.465 | |
| 3u57 | DH8 | Raucaffricine-O-beta-D-glucosidase | 3.2.1.125 | 0.465 | |
| 4keb | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.465 | |
| 1qjf | ACS | Isopenicillin N synthase | 1.21.3.1 | 0.464 | |
| 3ld5 | LDT | Aldose reductase | 1.1.1.21 | 0.464 | |
| 3v94 | WYQ | Phosphodiesterase | / | 0.464 | |
| 4wo5 | 324 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.464 | |
| 1isg | AGS | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2 | 3.2.2.6 | 0.463 | |
| 3r8h | ZOM | Aldo-keto reductase family 1 member C3 | / | 0.463 | |
| 4oew | 5IO | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.463 | |
| 1ejb | INJ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.462 | |
| 1ut6 | A8N | Acetylcholinesterase | 3.1.1.7 | 0.462 | |
| 1xom | CIO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.461 | |
| 4i9z | 5BA | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.461 | |
| 5agk | H4B | Nitric oxide synthase, brain | 1.14.13.39 | 0.461 | |
| 1kms | LIH | Dihydrofolate reductase | 1.5.1.3 | 0.460 | |
| 2h44 | 7CA | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.460 | |
| 2ipw | 2CL | Aldose reductase | 1.1.1.21 | 0.460 | |
| 3g4g | D71 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.460 | |
| 1dlr | MXA | Dihydrofolate reductase | 1.5.1.3 | 0.459 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.459 | |
| 1pqc | 444 | Oxysterols receptor LXR-beta | / | 0.459 | |
| 1zgb | A1E | Acetylcholinesterase | 3.1.1.7 | 0.459 | |
| 1zq5 | E04 | Aldo-keto reductase family 1 member C3 | / | 0.459 | |
| 2h42 | VIA | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.459 | |
| 2qw8 | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.459 | |
| 3g4k | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.459 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.459 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.458 | |
| 2ouy | CMP | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.458 | |
| 2vi5 | Y19 | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.458 | |
| 3sl6 | JN8 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.458 | |
| 3k45 | 51P | Dihydrofolate reductase | 1.5.1.3 | 0.457 | |
| 3nub | UD0 | UDP-2-acetamido-2-deoxy-3-oxo-D-glucuronate aminotransferase | 2.6.1.98 | 0.457 | |
| 3o73 | O73 | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.457 | |
| 4n3l | 2FN | Prothrombin | 3.4.21.5 | 0.457 | |
| 1d3d | BZT | Prothrombin | 3.4.21.5 | 0.456 | |
| 1hb3 | SCV | Isopenicillin N synthase | 1.21.3.1 | 0.456 | |
| 1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.456 | |
| 1sjw | NGV | Nogalonic acid methyl ester cyclase | / | 0.456 | |
| 1z3n | 3NA | Aldose reductase | 1.1.1.21 | 0.455 | |
| 3w5e | NVW | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.455 | |
| 2fm5 | M99 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.454 | |
| 2pdp | 393 | Aldose reductase | 1.1.1.21 | 0.454 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.454 | |
| 3nxv | D2F | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 3uzw | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.454 | |
| 4hf4 | 15H | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.454 | |
| 1efy | BZC | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.453 | |
| 1udt | VIA | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.453 | |
| 3r6i | JMS | Aldo-keto reductase family 1 member C3 | / | 0.453 | |
| 4ia0 | 5BB | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.453 | |
| 4qjc | IXE | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 1ohk | COP | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 1y2e | 5DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.452 | |
| 1z4i | UMP | 5'(3')-deoxyribonucleotidase, mitochondrial | 3.1.3 | 0.452 | |
| 2g22 | 6IG | Renin | 3.4.23.15 | 0.452 | |
| 3d3p | 20A | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.452 | |
| 4ajd | F04 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.452 | |
| 4nwi | CTN | 7-methylguanosine phosphate-specific 5'-nucleotidase | / | 0.452 | |
| 1u65 | CP0 | Acetylcholinesterase | 3.1.1.7 | 0.451 | |
| 2qo4 | CHD | Fatty acid-binding protein 10-A, liver basic | / | 0.451 | |
| 3n0h | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 3qm4 | PN0 | Cytochrome P450 2D6 | / | 0.451 | |
| 3r8g | IZP | Aldo-keto reductase family 1 member C3 | / | 0.451 | |
| 4fcb | 0T7 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.451 | |
| 4mvh | 2F5 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.451 | |
| 1eve | E20 | Acetylcholinesterase | 3.1.1.7 | 0.450 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.450 | |
| 1pd9 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 1pwl | BFI | Aldose reductase | 1.1.1.21 | 0.450 | |
| 1xon | PIL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.450 | |
| 3aiv | HBO | 4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase, chloroplastic | 3.2.1.182 | 0.450 | |
| 3r43 | ID8 | Aldo-keto reductase family 1 member C3 | / | 0.450 | |
| 1kyx | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.449 | |
| 1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.449 | |
| 1z71 | L17 | Prothrombin | 3.4.21.5 | 0.449 | |
| 2fzb | TOL | Aldose reductase | 1.1.1.21 | 0.449 | |
| 3nn6 | HNK | 6-hydroxy-L-nicotine oxidase | / | 0.449 | |
| 3wd9 | QPC | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.449 | |
| 4dbs | 0HV | Aldo-keto reductase family 1 member C3 | / | 0.449 | |
| 4llk | MEW | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.449 | |
| 1fvp | FMA | Non-fluorescent flavoprotein | / | 0.448 | |
| 1upw | 444 | Oxysterols receptor LXR-beta | / | 0.448 | |
| 2wsa | 646 | Glycylpeptide N-tetradecanoyltransferase | / | 0.448 | |
| 2xi4 | AFT | Acetylcholinesterase | 3.1.1.7 | 0.448 | |
| 3g58 | 988 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.448 | |
| 3jt3 | H4B | Nitric oxide synthase, brain | 1.14.13.39 | 0.448 | |
| 3sni | 546 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.448 | |
| 4b12 | C23 | Glycylpeptide N-tetradecanoyltransferase | / | 0.448 | |
| 4gv0 | 8ME | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.448 | |
| 4hhz | 15S | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.448 | |
| 1re0 | AFB | ADP-ribosylation factor 1 | / | 0.447 | |
| 1re0 | AFB | ARF guanine-nucleotide exchange factor 1 | / | 0.447 | |
| 1s3v | TQD | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 1zgv | 501 | Prothrombin | 3.4.21.5 | 0.447 | |
| 2ouu | 35G | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.447 | |
| 2vdy | HCY | Corticosteroid-binding globulin | / | 0.447 | |
| 2xlp | NAP | Putative flavin-containing monooxygenase | / | 0.447 | |
| 3arv | SAU | Chitinase A | / | 0.447 | |
| 3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.447 | |
| 3hmv | HBT | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.447 | |
| 3sl8 | JN7 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.447 | |
| 3zj6 | VM2 | Raucaffricine-O-beta-D-glucosidase | 3.2.1.125 | 0.447 | |
| 4fcd | 0T6 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.447 | |
| 4gv2 | 5ME | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.447 | |
| 1drf | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 1s36 | CEI | Obelin | / | 0.446 | |
| 2ipi | AKY | Aclacinomycin-N/aclacinomycin-A oxidase | / | 0.446 | |
| 2obx | INI | 6,7-dimethyl-8-ribityllumazine synthase 2 | 2.5.1.78 | 0.446 | |
| 2z3u | CRR | Cytochrome P450 | / | 0.446 | |
| 3ppk | FNI | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.446 | |
| 3zia | ADP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.446 | |
| 3zo7 | K6H | Muconolactone Delta-isomerase | / | 0.446 | |
| 4pab | THG | Dimethylglycine dehydrogenase, mitochondrial | 1.5.8.4 | 0.446 | |
| 1ro6 | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.445 | |
| 2hv5 | ZST | Aldose reductase | 1.1.1.21 | 0.445 | |
| 2ohh | FMN | Type A flavoprotein FprA | 1 | 0.445 | |
| 2ovv | PFH | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.445 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.445 | |
| 2zu9 | GDP | Mannosyl-3-phosphoglycerate synthase | 2.4.1.217 | 0.445 | |
| 3f3y | 4OA | Bile salt sulfotransferase | 2.8.2.14 | 0.445 | |
| 3k4s | 0MO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.445 | |
| 3n3z | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.445 | |
| 4lsa | BLD | Protein BRASSINOSTEROID INSENSITIVE 1 | 2.7.10.1 | 0.445 | |
| 4phl | PIL | Phosphodiesterase | / | 0.445 | |
| 1d3p | BT3 | Prothrombin | 3.4.21.5 | 0.444 | |
| 2d06 | EST | Sulfotransferase 1A1 | 2.8.2.1 | 0.444 | |
| 3m64 | 393 | Aldose reductase | 1.1.1.21 | 0.444 | |
| 3ug8 | IMN | Aldo-keto reductase family 1 member C3 | / | 0.444 | |
| 3uwe | VJJ | Aldo-keto reductase family 1 member C3 | / | 0.444 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
| 4bub | ADP | UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--LD-lysine ligase | / | 0.444 | |
| 1kyv | RBF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.443 | |
| 1pkf | EPD | Epothilone C/D epoxidase | 1.14 | 0.443 | |
| 1xoq | ROF | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.443 | |
| 1z6t | ADP | Apoptotic protease-activating factor 1 | / | 0.443 | |
| 3zj7 | C1K | Strictosidine-O-beta-D-glucosidase | 3.2.1.105 | 0.443 | |
| 4l34 | 1VG | Tankyrase-2 | 2.4.2.30 | 0.443 | |
| 4muw | 2F4 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.443 | |
| 4std | BFS | Scytalone dehydratase | 4.2.1.94 | 0.443 | |
| 1blz | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
| 1dig | L37 | C-1-tetrahydrofolate synthase, cytoplasmic | 1.5.1.5 | 0.442 | |
| 1p0p | BCH | Cholinesterase | 3.1.1.8 | 0.442 | |
| 1s2c | FLF | Aldo-keto reductase family 1 member C3 | / | 0.442 | |
| 1s9d | AFB | Cytohesin-2 | / | 0.442 | |
| 1s9d | AFB | ADP-ribosylation factor 1 | / | 0.442 | |
| 2b8j | ADN | Class B acid phosphatase | 3.1.3.2 | 0.442 | |
| 2fb8 | 215 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.442 | |
| 3cso | XNI | Genome polyprotein | 2.7.7.48 | 0.442 | |
| 3g4i | D71 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.442 | |
| 3tvx | PNX | cAMP-specific 3',5'-cyclic phosphodiesterase 4A | 3.1.4.53 | 0.442 | |
| 3wi2 | P98 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.442 | |
| 4gvs | F4M | Methenyltetrahydromethanopterin cyclohydrolase | 3.5.4.27 | 0.442 | |
| 1jum | BER | HTH-type transcriptional regulator QacR | / | 0.441 | |
| 1nqu | RDL | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.441 | |
| 2dv0 | ZST | Aldose reductase | 1.1.1.21 | 0.441 | |
| 2pb1 | NFG | Glucan 1,3-beta-glucosidase | / | 0.441 | |
| 2wo7 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.441 | |
| 2y0j | AXC | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.441 | |
| 2yg3 | FAD | Putrescine oxidase | / | 0.441 | |
| 3c72 | CX1 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.441 | |
| 3uzz | TES | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.441 | |
| 4hmn | 16J | Aldo-keto reductase family 1 member C3 | / | 0.441 | |
| 4j7h | TRH | PCZA361.3 | / | 0.441 | |
| 4nqg | CZH | Mitrocomin | / | 0.441 | |
| 1n9m | BTN | Streptavidin | / | 0.440 | |
| 1tbb | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.440 | |
| 1uwh | BAX | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.440 | |
| 1w19 | T1P | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.440 | |
| 2c94 | TSF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.440 | |
| 2jgs | BTN | Avidin | / | 0.440 | |
| 2pdl | TOL | Aldose reductase | 1.1.1.21 | 0.440 | |
| 2xlt | NA0 | Putative flavin-containing monooxygenase | / | 0.440 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.440 | |
| 3g1r | FIT | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.440 | |
| 3nhl | YTR | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.440 | |
| 4b65 | NDP | L-ornithine N(5)-monooxygenase | / | 0.440 | |
| 4qoh | STL | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.440 |