sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Modes are compared using Grim.
For more information, please see the following publication:
Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 5jsf | NAD | 17-beta-hydroxysteroid dehydrogenase 14 | 1.1.1 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Mode Similarity |
Align |
|---|---|---|---|---|---|
| 5jsf | NAD | 17-beta-hydroxysteroid dehydrogenase 14 | 1.1.1 | 1.299 | |
| 5js6 | NAD | 17-beta-hydroxysteroid dehydrogenase 14 | 1.1.1 | 1.272 | |
| 3nug | NAD | Pyridoxal 4-dehydrogenase | 1.1.1.107 | 1.032 | |
| 3wds | NAD | NADH-dependent quinuclidinone reductase | / | 1.029 | |
| 1geg | NAD | Diacetyl reductase [(S)-acetoin forming] | 1.1.1.304 | 1.003 | |
| 2gdz | NAD | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | 1.1.1.141 | 1.001 | |
| 5jla | NAD | Putative short-chain dehydrogenase/reductase | / | 0.996 | |
| 3ak4 | NAD | NADH-dependent quinuclidinone reductase | / | 0.993 | |
| 2d1y | NAD | Oxidoreductase, short-chain dehydrogenase/reductase family | / | 0.979 | |
| 1x7h | NDP | Putative ketoacyl reductase | 1.3.1 | 0.960 | |
| 2wsb | NAD | Galactitol dehydrogenase | / | 0.960 | |
| 2q2v | NAD | Beta-D-hydroxybutyrate dehydrogenase | / | 0.944 | |
| 4z3d | NDP | Carbonyl reductase [NADPH] 1 | 1.1.1.184 | 0.944 | |
| 3pgx | NAD | Uncharacterized NAD-dependent oxidoreductase MAP_4146 | / | 0.941 | |
| 1x7g | NAP | Putative ketoacyl reductase | 1.3.1 | 0.939 | |
| 4dc0 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.939 | |
| 3w8d | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.937 | |
| 3w8f | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.936 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.931 | |
| 3w8e | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.927 | |
| 3qrw | NDP | Putative ketoacyl reductase | 1.3.1 | 0.912 | |
| 4gh5 | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.911 | |
| 4b79 | NAD | Probable short-chain dehydrogenase | / | 0.909 | |
| 4dc1 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.909 | |
| 3a28 | NAD | L-2,3-butanediol dehydrogenase | 1.1.1.76 | 0.907 | |
| 3s55 | NAD | Putative short-chain dehydrogenase/reductase | / | 0.907 | |
| 2o23 | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.902 | |
| 3sx2 | NAD | Uncharacterized protein | / | 0.901 | |
| 4nbt | NAD | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.900 | |
| 1g0n | NDP | Tetrahydroxynaphthalene reductase | 1.1.1.252 | 0.899 | |
| 3vdq | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.896 | |
| 3p19 | NDP | Putative blue fluorescent protein | / | 0.892 | |
| 4kwh | NAP | Reductase homolog | / | 0.886 | |
| 1nfr | NAD | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.880 | |
| 3ai2 | NDP | NADPH-sorbose reductase | / | 0.878 | |
| 3rj5 | NAD | Alcohol dehydrogenase | 1.1.1.1 | 0.878 | |
| 4is3 | NAD | 3alpha-hydroxy bile acid-CoA-ester 3-dehydrogenase 2 | 1.17.98.1 | 0.878 | |
| 1h5q | NAP | NADP-dependent mannitol dehydrogenase | 1.1.1.138 | 0.877 | |
| 1edo | NAP | 3-oxoacyl-[acyl-carrier-protein] reductase 1, chloroplastic | 1.1.1.100 | 0.874 | |
| 2ztl | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.871 | |
| 4fn4 | NAD | Short chain dehydrogenase | / | 0.870 | |
| 4wec | NAD | Short chain dehydrogenase | / | 0.867 | |
| 1ae1 | NAP | Tropinone reductase 1 | / | 0.866 | |
| 1nff | NAD | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.865 | |
| 3o26 | NDP | Salutaridine reductase | / | 0.863 | |
| 2dte | NAI | Glucose 1-dehydrogenase related protein | / | 0.854 | |
| 3rj9 | NAD | Alcohol dehydrogenase | 1.1.1.1 | 0.853 | |
| 3tsc | NAD | Uncharacterized protein | / | 0.853 | |
| 4iqg | NAP | Short-chain dehydrogenase/reductase SDR | / | 0.853 | |
| 2ekp | NAD | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.852 | |
| 2wdz | NAD | Galactitol dehydrogenase | / | 0.851 | |
| 3geg | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.849 | |
| 2ag5 | NAD | 3-hydroxybutyrate dehydrogenase type 2 | / | 0.848 | |
| 3ai3 | NDP | NADPH-sorbose reductase | / | 0.848 | |
| 4bmv | NAP | Short-chain dehydrogenase | / | 0.847 | |
| 2bd0 | NAP | Sepiapterin reductase | / | 0.846 | |
| 1gee | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.845 | |
| 3ruc | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.844 | |
| 2ztm | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.843 | |
| 2y99 | NAD | Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase | 1.3.1.56 | 0.841 | |
| 1gco | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.840 | |
| 2ztv | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.840 | |
| 5ig2 | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.840 | |
| 1e6w | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.839 | |
| 4rf2 | NAP | NADPH dependent R-specific alcohol dehydrogenase | / | 0.837 | |
| 3sju | NDP | Keto reductase | / | 0.832 | |
| 4yag | NAI | C alpha-dehydrogenase | / | 0.828 | |
| 1rwb | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.827 | |
| 2b4q | NAP | Rhamnolipids biosynthesis 3-oxoacyl-[acyl-carrier-protein] reductase | 1.1.1.100 | 0.825 | |
| 3d3w | NAP | L-xylulose reductase | 1.1.1.10 | 0.823 | |
| 1n5d | NDP | Carbonyl reductase [NADPH] 1 | / | 0.822 | |
| 1e3s | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.821 | |
| 2q2q | NAD | Beta-D-hydroxybutyrate dehydrogenase | / | 0.818 | |
| 3tn7 | NJP | Short-chain alcohol dehydrogenase | / | 0.816 | |
| 1u7t | TDT | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.815 | |
| 3qwf | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.815 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.812 | |
| 4hp8 | NAP | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.810 | |
| 2jah | NDP | Clavaldehyde dehydrogenase | / | 0.809 | |
| 1cyd | NDP | Carbonyl reductase [NADPH] 2 | 1.1.1.184 | 0.808 | |
| 1ipe | NDP | Tropinone reductase 2 | 1.1.1.236 | 0.808 | |
| 3ndr | NAD | Pyridoxal 4-dehydrogenase | 1.1.1.107 | 0.807 | |
| 1e3w | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.806 | |
| 1w4z | NAP | Putative ketoacyl reductase | 1.3.1 | 0.806 | |
| 3gy0 | NAP | NAD(P)-dependent oxidoreductase | / | 0.804 | |
| 4qec | NAP | ElxO | / | 0.803 | |
| 1vl8 | NAP | Oxidoreductase, short chain dehydrogenase/reductase family | / | 0.800 | |
| 3bhi | NAP | Carbonyl reductase [NADPH] 1 | 1.1.1.184 | 0.799 | |
| 1zem | NAD | Xylitol dehydrogenase | / | 0.798 | |
| 5idw | NAP | Short-chain dehydrogenase/reductase SDR | / | 0.798 | |
| 1g6k | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.797 | |
| 2zat | NAP | Dehydrogenase/reductase SDR family member 4 | 1.1.1.184 | 0.796 | |
| 3o4r | NAP | Dehydrogenase/reductase SDR family member 4 | 1.1.1.184 | 0.796 | |
| 4qed | NAP | ElxO | / | 0.793 | |
| 1bdb | NAD | Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase | / | 0.791 | |
| 1pr9 | NAP | L-xylulose reductase | 1.1.1.10 | 0.789 | |
| 1fdu | NAP | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.788 | |
| 1i2b | NAD | UDP-sulfoquinovose synthase, chloroplastic | 3.13.1.1 | 0.788 | |
| 2rbe | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.787 | |
| 4hwk | NAP | Sepiapterin reductase | 1.1.1.153 | 0.787 | |
| 2c29 | NAP | Dihydroflavonol 4-reductase | / | 0.786 | |
| 2dkn | NAI | 3-alpha-hydroxysteroid dehydrogenase | / | 0.786 | |
| 4m87 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.785 | |
| 2ztu | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.784 | |
| 1xse | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.783 | |
| 4nbu | NAI | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.783 | |
| 3iah | NAP | Putative oxoacyl-(Acyl carrier protein) reductase | / | 0.780 | |
| 4yai | NAI | C alpha-dehydrogenase | / | 0.780 | |
| 1mg5 | NAI | Alcohol dehydrogenase | 1.1.1.1 | 0.778 | |
| 4o0l | NDP | NADPH-dependent 3-quinuclidinone reductase | / | 0.776 | |
| 4j7x | NAP | Sepiapterin reductase | 1.1.1.153 | 0.772 | |
| 4u7w | NDP | MxaA | / | 0.772 | |
| 3r3s | NAD | Putative oxidoreductase | / | 0.771 | |
| 1b2l | NDC | Alcohol dehydrogenase | 1.1.1.1 | 0.770 | |
| 1xkq | NDP | Uncharacterized protein | / | 0.769 | |
| 3ruf | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.769 | |
| 1xg5 | NAP | Dehydrogenase/reductase SDR family member 11 | / | 0.768 | |
| 4j7u | NAP | Sepiapterin reductase | 1.1.1.153 | 0.768 | |
| 4bms | NAP | Alclohol dehydrogenase/short-chain dehydrogenase | / | 0.766 | |
| 4k6f | NAP | Putative Acetoacetyl-CoA reductase | / | 0.766 | |
| 3rku | NAP | NADP-dependent 3-hydroxy acid dehydrogenase | / | 0.765 | |
| 4pvd | NDP | NADPH-dependent methylglyoxal reductase GRE2 | / | 0.765 | |
| 2q1w | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.762 | |
| 4lis | NAD | UDP-glucose 4-epimerase (Eurofung) | / | 0.762 | |
| 1oaa | NAP | Sepiapterin reductase | 1.1.1.153 | 0.761 | |
| 2q1t | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.761 | |
| 1kvr | NAD | UDP-glucose 4-epimerase | 5.1.3.2 | 0.759 | |
| 2hrb | NAP | Carbonyl reductase [NADPH] 3 | 1.1.1.184 | 0.759 | |
| 1ek5 | NAD | UDP-glucose 4-epimerase | / | 0.756 | |
| 4nbw | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.756 | |
| 1b15 | NAE | Alcohol dehydrogenase | 1.1.1.1 | 0.755 | |
| 3ruh | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.755 | |
| 4hxy | NDP | Plm1 | / | 0.755 | |
| 3icp | NAD | NAD-dependent epimerase/dehydratase | / | 0.753 | |
| 1sby | NAD | Alcohol dehydrogenase | 1.1.1.1 | 0.751 | |
| 1u7t | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.751 | |
| 3ko8 | NAD | NAD-dependent epimerase/dehydratase | / | 0.751 | |
| 2wyv | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.750 | |
| 2yy7 | NAD | L-threonine dehydrogenase | / | 0.749 | |
| 2c59 | NAD | GDP-mannose 3,5-epimerase | 5.1.3.18 | 0.748 | |
| 4oxy | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.748 | |
| 1iy8 | NAD | Levodione reductase | / | 0.747 | |
| 2p5y | NAD | UDP-glucose 4-epimerase | / | 0.744 | |
| 2bgm | NAJ | Secoisolariciresinol dehydrogenase | 1.1.1.331 | 0.743 | |
| 3aut | NAI | Glucose 1-dehydrogenase 4 | 1.1.1.47 | 0.743 | |
| 4zju | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.743 | |
| 1g1a | NAD | dTDP-glucose 4,6-dehydratase | / | 0.741 | |
| 2nnl | NAP | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.741 | |
| 3tox | NAP | Putative oxidoreductase | / | 0.741 | |
| 1b16 | NAQ | Alcohol dehydrogenase | 1.1.1.1 | 0.740 | |
| 4i5e | NAP | Alclohol dehydrogenase/short-chain dehydrogenase | / | 0.740 | |
| 2ntj | P1H | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.737 | |
| 3o03 | NAP | Dehydrogenase with different specificities (Related to short-chain alcohol dehydrogenase) | / | 0.735 | |
| 3aw9 | NAD | NAD-dependent epimerase/dehydratase | / | 0.733 | |
| 3mje | NDP | AmphB | / | 0.733 | |
| 4fw8 | NAI | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.733 | |
| 3lu1 | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.732 | |
| 1qyv | NAP | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.731 | |
| 3rua | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.731 | |
| 2q1s | NAI | Putative nucleotide sugar epimerase/ dehydratase | / | 0.730 | |
| 5koi | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.729 | |
| 2q1u | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.728 | |
| 4cql | NAD | Estradiol 17-beta-dehydrogenase 8 | 1.1.1.62 | 0.728 | |
| 4dmm | NAP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.728 | |
| 1eny | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.727 | |
| 1sny | NAP | LD36273p | / | 0.727 | |
| 1orr | NAD | CDP-paratose 2-epimerase | / | 0.726 | |
| 1bxk | NAD | dTDP-glucose 4,6-dehydratase 2 | / | 0.724 | |
| 3rud | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.723 | |
| 2b35 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.722 | |
| 3a4v | NAD | NDP-sugar epimerase | / | 0.721 | |
| 3g49 | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.721 | |
| 3sxp | NAD | ADP-L-glycero-D-mannoheptose-6-epimerase | / | 0.720 | |
| 4yac | NAI | C alpha-dehydrogenase | / | 0.720 | |
| 1ahh | NAD | 7-alpha-hydroxysteroid dehydrogenase | 1.1.1.159 | 0.719 | |
| 2idz | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.718 | |
| 1rkx | NAD | CDP-D-glucose-4,6-dehydratase | / | 0.717 | |
| 3bmo | NAP | Pteridine reductase | / | 0.717 | |
| 3uce | NDP | Dehydrogenase | / | 0.716 | |
| 3ru9 | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.714 | |
| 3rue | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.714 | |
| 4fj1 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.714 | |
| 3oey | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.713 | |
| 5cpb | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.712 | |
| 1i3l | NAD | UDP-glucose 4-epimerase | / | 0.711 | |
| 3uic | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.711 | |
| 3pvz | NAD | UDP-N-acetylglucosamine 4,6-dehydratase | / | 0.709 | |
| 3wfj | NAD | 2-dehydropantoate 2-reductase | / | 0.709 | |
| 2ggs | NDP | dTDP-4-dehydrorhamnose reductase | / | 0.707 | |
| 1fk8 | NAD | 3-alpha-hydroxysteroid dehydrogenase/carbonyl reductase | 1.1.1.50 | 0.706 | |
| 2ydx | NAP | Methionine adenosyltransferase 2 subunit beta | / | 0.705 | |
| 4egb | NAD | dTDP-glucose 4,6-dehydratase | / | 0.705 | |
| 3ajr | NAD | NDP-sugar epimerase | / | 0.703 | |
| 5jy1 | NAD | Putative short-chain dehydrogenase/reductase | / | 0.703 | |
| 3a9w | NAD | NDP-sugar epimerase | / | 0.702 | |
| 3ru7 | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.701 | |
| 3wmx | NAD | NAD dependent epimerase/dehydratase | / | 0.701 | |
| 2h9i | EAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.700 | |
| 1b14 | NAD | Alcohol dehydrogenase | 1.1.1.1 | 0.699 | |
| 4idg | NAD | Putative UDP-glucose 4-epimerase | / | 0.699 | |
| 3sj7 | NDP | 3-oxoacyl-(Acyl-carrier-protein) reductase, putative | / | 0.697 | |
| 4fj0 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.696 | |
| 4bqp | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.695 | |
| 5lc1 | NAD | L-threonine 3-dehydrogenase | / | 0.695 | |
| 2q28 | ADP | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.694 | |
| 2aq8 | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.693 | |
| 5jyd | NAD | Short chain dehydrogenase | / | 0.693 | |
| 2ewm | NAD | (S)-1-Phenylethanol dehydrogenase | 1.1.1.311 | 0.691 | |
| 4fj2 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.691 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.690 | |
| 2b37 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.689 | |
| 3ijr | NAD | Oxidoreductase, short chain dehydrogenase/reductase family | / | 0.689 | |
| 4ej0 | NAP | ADP-L-glycero-D-manno-heptose-6-epimerase | / | 0.689 | |
| 1w73 | NAP | 2,4-dienoyl-CoA reductase, mitochondrial | 1.3.1.34 | 0.688 | |
| 2ie0 | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.688 | |
| 3pdu | NAP | Glyoxalate/3-oxopropanoate/4-oxobutanoate reductase | / | 0.688 | |
| 3zu2 | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.688 | |
| 4eso | NAP | Putative oxidoreductase | / | 0.688 | |
| 2b69 | NAD | UDP-glucuronic acid decarboxylase 1 | 4.1.1.35 | 0.687 | |
| 2hsd | NAD | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.687 | |
| 2nv6 | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.687 | |
| 4dre | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.686 | |
| 4y9d | NAI | C alpha-dehydrogenase | / | 0.686 | |
| 5d2e | NAP | MlnE | / | 0.686 | |
| 1eq2 | NAP | ADP-L-glycero-D-manno-heptose-6-epimerase | / | 0.684 | |
| 3of2 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.684 | |
| 4bgi | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.684 | |
| 2aqh | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.682 | |
| 1n2s | NAI | dTDP-4-dehydrorhamnose reductase | 1.1.1.133 | 0.681 | |
| 2c20 | NAD | UDP-glucose 4-epimerase | / | 0.681 | |
| 2pzj | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.681 | |
| 3l77 | NJP | Short-chain alcohol dehydrogenase | / | 0.680 | |
| 4b8z | NAP | GDP-L-fucose synthase | 1.1.1.271 | 0.680 | |
| 4lk3 | NAD | UDP-glucuronic acid decarboxylase 1 | 4.1.1.35 | 0.679 | |
| 1enz | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.678 | |
| 3pef | NAP | Glyoxalate/3-oxopropanoate/4-oxobutanoate reductase | / | 0.678 | |
| 4bii | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.678 | |
| 1w8d | NAP | 2,4-dienoyl-CoA reductase, mitochondrial | 1.3.1.34 | 0.677 | |
| 2c54 | NAD | GDP-mannose 3,5-epimerase | 5.1.3.18 | 0.677 | |
| 3ehe | NAD | UDP-glucose 4-epimerase (GalE-1) | / | 0.675 | |
| 3f1k | NAP | Uncharacterized oxidoreductase YciK | 1 | 0.675 | |
| 1nai | NAD | UDP-glucose 4-epimerase | 5.1.3.2 | 0.674 | |
| 2yg5 | FAD | Putrescine oxidase | / | 0.673 | |
| 3h2s | NDP | Putative NADH-flavin reductase | / | 0.673 | |
| 4bkq | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.673 | |
| 4iv8 | SAM | Phosphoethanolamine N-methyltransferase,putative | / | 0.673 | |
| 2jib | ADP | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.672 | |
| 2yw9 | NAP | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.672 | |
| 2ieb | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.671 | |
| 2ji9 | ADP | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.671 | |
| 2aqi | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.670 | |
| 4trn | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.670 | |
| 2x6t | NAP | ADP-L-glycero-D-manno-heptose-6-epimerase | / | 0.669 | |
| 3w6u | NAP | 6-phosphogluconate dehydrogenase, NAD-binding protein | / | 0.669 | |
| 4a99 | FAD | TetX family tetracycline inactivation enzyme | / | 0.669 | |
| 1d2h | SAH | Glycine N-methyltransferase | 2.1.1.20 | 0.668 | |
| 1rpn | NDP | GDP-mannose 4,6-dehydratase | / | 0.667 | |
| 4e5y | NDP | GDP-L-fucose synthase | 1.1.1.271 | 0.667 | |
| 5je3 | SAH | Methyl transferase | / | 0.667 | |
| 3a1n | NAD | NDP-sugar epimerase | / | 0.666 | |
| 4emi | NAD | Toluene 1,2-dioxygenase system ferredoxin--NAD(+) reductase component | 1.18.1.3 | 0.666 | |
| 2x3n | FAD | Probable FAD-dependent monooxygenase | / | 0.665 | |
| 2hun | NAD | 336aa long hypothetical dTDP-glucose 4,6-dehydratase | / | 0.664 | |
| 2yg7 | FAD | Putrescine oxidase | / | 0.664 | |
| 3v8v | SAM | Ribosomal RNA large subunit methyltransferase K/L | 2.1.1.173 | 0.664 | |
| 1akc | PPE | Aspartate aminotransferase, mitochondrial | 2.6.1.1 | 0.663 | |
| 1nbi | SAM | Glycine N-methyltransferase | 2.1.1.20 | 0.662 | |
| 1wy7 | SAH | Uncharacterized protein | / | 0.662 | |
| 4o1m | NAD | Enoyl-acyl carrier reductase | / | 0.662 | |
| 1boo | SAH | Modification methylase PvuII | 2.1.1.113 | 0.661 | |
| 2rcy | NAP | Pyrroline-5-carboxylate reductase | / | 0.661 | |
| 3kkz | SAM | Uncharacterized protein | / | 0.661 | |
| 3lzw | FAD | Ferredoxin--NADP reductase 2 | 1.18.1.2 | 0.661 | |
| 3sso | SAH | Mycinamicin VI 2''-O-methyltransferase | / | 0.661 | |
| 4gll | NAD | UDP-glucuronic acid decarboxylase 1 | 4.1.1.35 | 0.660 | |
| 4xgi | NAD | Glutamate dehydrogenase | / | 0.660 | |
| 1bc5 | SAH | Chemotaxis protein methyltransferase | 2.1.1.80 | 0.659 | |
| 1hdo | NAP | Flavin reductase (NADPH) | / | 0.659 | |
| 2bgl | NAJ | Secoisolariciresinol dehydrogenase | 1.1.1.331 | 0.659 | |
| 3g5q | FAD | Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO | / | 0.659 | |
| 3sgl | SAM | tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC | / | 0.659 | |
| 1wg8 | SAM | Ribosomal RNA small subunit methyltransferase H | / | 0.658 | |
| 5dx1 | SFG | Histone-arginine methyltransferase CARM1 | / | 0.656 | |
| 1l3i | SAH | Probable cobalt-precorrin-6B C(15)-methyltransferase (decarboxylating) | / | 0.655 | |
| 2g1p | SAH | DNA adenine methylase | 2.1.1.72 | 0.655 | |
| 5dwq | SFG | Histone-arginine methyltransferase CARM1 | / | 0.655 | |
| 1f0y | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.654 | |
| 2fjb | SFD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.654 | |
| 2gn8 | NAP | UDP-N-acetylglucosamine 4,6-dehydratase (inverting) | 4.2.1.115 | 0.654 | |
| 3bgv | SAH | mRNA cap guanine-N7 methyltransferase | 2.1.1.56 | 0.654 | |
| 3f3s | NAD | Lambda-crystallin homolog | / | 0.653 | |
| 4b8w | NAP | GDP-L-fucose synthase | 1.1.1.271 | 0.653 | |
| 5bxy | SAH | Putative RNA methylase family UPF0020 | / | 0.653 | |
| 1kc1 | NDP | dTDP-4-dehydrorhamnose reductase | 1.1.1.133 | 0.652 | |
| 2i9k | SAH | Modification methylase HhaI | 2.1.1.37 | 0.652 | |
| 2ntv | P1H | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.652 | |
| 2o06 | MTA | Spermidine synthase | 2.5.1.16 | 0.652 | |
| 3nn6 | FB0 | 6-hydroxy-L-nicotine oxidase | / | 0.652 | |
| 4dti | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.652 | |
| 2p5u | NAD | UDP-glucose 4-epimerase | / | 0.651 | |
| 2aqk | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.650 | |
| 2yut | NAP | Putative short-chain oxidoreductase | / | 0.650 |