sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Modes are compared using Grim.
For more information, please see the following publication:
Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4iv8 | SAM | Phosphoethanolamine N-methyltransferase,putative |
| PDB ID | HET | Uniprot Name | EC Number | Binding Mode Similarity |
Align |
|---|---|---|---|---|---|
| 4iv8 | SAM | Phosphoethanolamine N-methyltransferase,putative | / | 0.842 | |
| 3uj8 | SFG | Phosphoethanolamine N-methyltransferase | / | 0.778 | |
| 4mwz | SAM | Phosphoethanolamine N-methyltransferase, putative | / | 0.770 | |
| 4yv2 | S4M | Spermidine synthase, putative | / | 0.762 | |
| 4fgz | SAH | Phosphoethanolamine N-methyltransferase | / | 0.761 | |
| 2o07 | MTA | Spermidine synthase | 2.5.1.16 | 0.757 | |
| 4yuz | S4M | Spermidine synthase, putative | / | 0.757 | |
| 2o06 | MTA | Spermidine synthase | 2.5.1.16 | 0.751 | |
| 5je3 | SAH | Methyl transferase | / | 0.744 | |
| 4obw | SAM | 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial | / | 0.743 | |
| 4qdk | SAH | Magnesium-protoporphyrin O-methyltransferase | 2.1.1.11 | 0.741 | |
| 2pan | FAD | Glyoxylate carboligase | 4.1.1.47 | 0.738 | |
| 4iv0 | SAM | Phosphoethanolamine N-methyltransferase, putative | / | 0.738 | |
| 2hv9 | SFG | mRNA cap guanine-N7 methyltransferase | 2.1.1.56 | 0.735 | |
| 4o29 | SAH | Protein-L-isoaspartate O-methyltransferase | / | 0.734 | |
| 5dst | SAH | Protein arginine N-methyltransferase 8 | 2.1.1 | 0.730 | |
| 5jdz | SAH | Methyl transferase | / | 0.729 | |
| 3uj7 | SAM | Phosphoethanolamine N-methyltransferase | / | 0.728 | |
| 5je4 | SAH | Methyl transferase | / | 0.728 | |
| 2p35 | SAH | Trans-aconitate 2-methyltransferase | / | 0.725 | |
| 4yv0 | S4M | Spermidine synthase, putative | / | 0.725 | |
| 3rw9 | DSH | Spermidine synthase | 2.5.1.16 | 0.724 | |
| 3ea4 | FAB | Acetolactate synthase, chloroplastic | 2.2.1.6 | 0.723 | |
| 4yuv | S4M | Spermidine synthase, putative | / | 0.723 | |
| 4yv1 | S4M | Spermidine synthase, putative | / | 0.723 | |
| 4krh | SAM | Phosphoethanolamine N-methyltransferase 2 | / | 0.722 | |
| 3e9y | FAB | Acetolactate synthase, chloroplastic | 2.2.1.6 | 0.721 | |
| 5epe | SAH | Uncharacterized protein | / | 0.720 | |
| 2pt6 | S4M | Spermidine synthase | / | 0.718 | |
| 1ri3 | SAH | mRNA cap guanine-N7 methyltransferase | 2.1.1.56 | 0.717 | |
| 2ibt | NEA | Modification methylase TaqI | 2.1.1.72 | 0.717 | |
| 1ahh | NAD | 7-alpha-hydroxysteroid dehydrogenase | 1.1.1.159 | 0.714 | |
| 4yac | NAI | C alpha-dehydrogenase | / | 0.714 | |
| 2qe6 | SAM | Uncharacterized protein | / | 0.712 | |
| 1kr5 | SAH | Protein-L-isoaspartate(D-aspartate) O-methyltransferase | 2.1.1.77 | 0.711 | |
| 2hmv | ADP | Ktr system potassium uptake protein A | / | 0.711 | |
| 4gqb | 0XU | Protein arginine N-methyltransferase 5 | / | 0.711 | |
| 1y9d | FAD | Pyruvate oxidase | 1.2.3.3 | 0.710 | |
| 4hc4 | SAH | Protein arginine N-methyltransferase 6 | / | 0.710 | |
| 1z3c | SA8 | mRNA cap guanine-N7 methyltransferase | 2.1.1.56 | 0.709 | |
| 4r6x | SAH | Phosphoethanolamine N-methyltransferase | / | 0.708 | |
| 1d2h | SAH | Glycine N-methyltransferase | 2.1.1.20 | 0.707 | |
| 2zzm | SAM | tRNA (guanine(37)-N1)-methyltransferase Trm5b | 2.1.1.228 | 0.707 | |
| 3b3f | SAH | Histone-arginine methyltransferase CARM1 | / | 0.707 | |
| 2yx1 | SFG | tRNA (guanine(37)-N1)-methyltransferase Trm5b | 2.1.1.228 | 0.706 | |
| 3tos | SAH | CalS11 | / | 0.704 | |
| 4nec | SAH | Putative SAM-dependent methyltransferase | / | 0.704 | |
| 3g07 | SAM | 7SK snRNA methylphosphate capping enzyme | 2.1.1 | 0.702 | |
| 1skm | SAH | Modification methylase HhaI | 2.1.1.37 | 0.701 | |
| 3fpf | MTA | Uncharacterized protein | / | 0.701 | |
| 5dx8 | SFG | Histone-arginine methyltransferase CARM1 | / | 0.700 | |
| 2yvl | SAM | tRNA (adenine(58)-N(1))-methyltransferase TrmI | / | 0.699 | |
| 1y8q | ATP | SUMO-activating enzyme subunit 2 | 6.3.2 | 0.698 | |
| 2hnk | SAH | SAM-dependent O-methyltransferase | / | 0.698 | |
| 2vdv | SAM | tRNA (guanine-N(7)-)-methyltransferase | / | 0.698 | |
| 3sso | SAH | Mycinamicin VI 2''-O-methyltransferase | / | 0.697 | |
| 5dx1 | SFG | Histone-arginine methyltransferase CARM1 | / | 0.697 | |
| 2ih2 | NEA | Modification methylase TaqI | 2.1.1.72 | 0.696 | |
| 2eju | SAH | tRNA (guanine(26)-N(2))-dimethyltransferase | / | 0.695 | |
| 2wsb | NAD | Galactitol dehydrogenase | / | 0.694 | |
| 2y1w | SFG | Histone-arginine methyltransferase CARM1 | / | 0.694 | |
| 3lhd | SAH | tRNA (adenine(57)-N(1)/adenine(58)-N(1))-methyltransferase TrmI | 2.1.1.219 | 0.694 | |
| 4c04 | SFG | Protein arginine N-methyltransferase 6 | / | 0.694 | |
| 4fzv | SAM | 5-methylcytosine rRNA methyltransferase NSUN4 | 2.1.1 | 0.694 | |
| 5dxj | SFG | Histone-arginine methyltransferase CARM1 | / | 0.694 | |
| 1g1a | NAD | dTDP-glucose 4,6-dehydratase | / | 0.693 | |
| 2okc | SAM | Probable type I restriction enzyme BthVORF4518P M protein | 2.1.1.72 | 0.693 | |
| 3qow | SAM | Histone-lysine N-methyltransferase, H3 lysine-79 specific | 2.1.1.43 | 0.693 | |
| 4b69 | FAD | L-ornithine N(5)-monooxygenase | / | 0.693 | |
| 4hh4 | SAH | CcbJ | / | 0.693 | |
| 3a26 | MTA | tRNA(Phe) (4-demethylwyosine(37)-C(7)) aminocarboxypropyltransferase | / | 0.692 | |
| 4qpp | SAH | Protein arginine N-methyltransferase 6 | / | 0.692 | |
| 1f3l | SAH | Protein arginine N-methyltransferase 3 | / | 0.691 | |
| 2dji | FAD | Pyruvate oxidase | / | 0.691 | |
| 4kwc | SAH | Methyltransferase domain family | / | 0.691 | |
| 4nzh | FAD | L-ornithine N(5)-monooxygenase | / | 0.690 | |
| 1pow | FAD | Pyruvate oxidase | 1.2.3.3 | 0.689 | |
| 1qzz | SAM | Aclacinomycin 10-hydroxylase RdmB | 4.1.1 | 0.689 | |
| 3dlc | SAM | SAM (And some other nucleotide) binding motif:Generic methyltransferase | / | 0.689 | |
| 4lwp | SAH | Arginine N-methyltransferase, putative | / | 0.689 | |
| 4nbu | NAI | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.689 | |
| 4wec | NAD | Short chain dehydrogenase | / | 0.689 | |
| 5je2 | SAH | Methyl transferase | / | 0.689 | |
| 1g60 | SAM | Modification methylase MboII | 2.1.1.72 | 0.688 | |
| 5i39 | FAD | L-amino acid deaminase | / | 0.688 | |
| 3bgi | SAH | Thiopurine S-methyltransferase | 2.1.1.67 | 0.687 | |
| 4htf | SAM | tRNA 5-carboxymethoxyuridine methyltransferase | / | 0.687 | |
| 1pox | FAD | Pyruvate oxidase | 1.2.3.3 | 0.686 | |
| 2ih5 | NEA | Modification methylase TaqI | 2.1.1.72 | 0.686 | |
| 4c03 | SFG | Protein arginine N-methyltransferase 6 | / | 0.686 | |
| 4c05 | SAH | Protein arginine N-methyltransferase 6 | / | 0.686 | |
| 4tm1 | FDA | KtzI | / | 0.686 | |
| 1v5e | FAD | Pyruvate oxidase | / | 0.685 | |
| 3oc4 | FAD | Oxidoreductase, pyridine nucleotide-disulfide family | / | 0.685 | |
| 3v8v | SAM | Ribosomal RNA large subunit methyltransferase K/L | 2.1.1.173 | 0.685 | |
| 1l3i | SAH | Probable cobalt-precorrin-6B C(15)-methyltransferase (decarboxylating) | / | 0.684 | |
| 1wy7 | SAH | Uncharacterized protein | / | 0.684 | |
| 3kkj | FAD | Renalase | / | 0.684 | |
| 3go4 | SAH | Uncharacterized protein | / | 0.683 | |
| 3pb3 | SAH | 16S rRNA (adenine(1408)-N(1))-methyltransferase | 2.1.1.180 | 0.683 | |
| 4gh5 | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.683 | |
| 1ri4 | SAM | mRNA cap guanine-N7 methyltransferase | 2.1.1.56 | 0.682 | |
| 2nyu | SAM | rRNA methyltransferase 2, mitochondrial | / | 0.682 | |
| 2zul | SAM | Probable ribosomal RNA small subunit methyltransferase | / | 0.682 | |
| 3lsh | FAD | Pyranose 2-oxidase | / | 0.682 | |
| 5hxw | FAD | L-amino acid deaminase | / | 0.682 | |
| 2fkn | NAD | Urocanate hydratase | 4.2.1.49 | 0.680 | |
| 2fje | FAD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.678 | |
| 2ji7 | ADP | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.678 | |
| 2pwy | SAH | tRNA (adenine(58)-N(1))-methyltransferase TrmI | 2.1.1.220 | 0.678 | |
| 3lcv | SAM | 16S rRNA (guanine(1405)-N(7))-methyltransferase | 2.1.1.179 | 0.678 | |
| 3nug | NAD | Pyridoxal 4-dehydrogenase | 1.1.1.107 | 0.678 | |
| 3cox | FAD | Cholesterol oxidase | 1.1.3.6 | 0.677 | |
| 3grv | ADN | Probable ribosomal RNA small subunit methyltransferase A | / | 0.677 | |
| 3n1s | 5GP | Purine nucleoside phosphoramidase | / | 0.677 | |
| 3p2e | SAH | 16S rRNA (adenine(1408)-N(1))-methyltransferase | 2.1.1.180 | 0.677 | |
| 1ori | SAH | Protein arginine N-methyltransferase 1 | / | 0.676 | |
| 3a27 | SAM | tRNA(Phe) (4-demethylwyosine(37)-C(7)) aminocarboxypropyltransferase | / | 0.676 | |
| 3dmg | SAH | Probable ribosomal RNA small subunit methyltransferase | / | 0.676 | |
| 3gsi | FAD | Dimethylglycine oxidase | 1.5.3.10 | 0.676 | |
| 3orh | SAH | Guanidinoacetate N-methyltransferase | 2.1.1.2 | 0.676 | |
| 1qao | SAM | rRNA adenine N-6-methyltransferase | 2.1.1.184 | 0.675 | |
| 1zx9 | FAD | Mercuric reductase | 1.16.1.1 | 0.675 | |
| 1rje | SAH | Leucine carboxyl methyltransferase 1 | 2.1.1.233 | 0.674 | |
| 3he3 | FAD | UDP-galactopyranose mutase | / | 0.674 | |
| 4qnv | GEK | tRNA U34 carboxymethyltransferase | / | 0.674 | |
| 5bp7 | SAH | SAM-dependent methyltransferase | / | 0.674 | |
| 3cbg | SAH | O-methyltransferase | / | 0.673 | |
| 5js6 | NAD | 17-beta-hydroxysteroid dehydrogenase 14 | 1.1.1 | 0.673 | |
| 5jsf | NAD | 17-beta-hydroxysteroid dehydrogenase 14 | 1.1.1 | 0.673 | |
| 1cbo | FAD | Cholesterol oxidase | 1.1.3.6 | 0.672 | |
| 1jnz | FAD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.672 | |
| 4d79 | ATP | tRNA threonylcarbamoyladenosine dehydratase | 6.1 | 0.672 | |
| 4rek | FAD | Cholesterol oxidase | 1.1.3.6 | 0.672 | |
| 4tm4 | FDA | KtzI | / | 0.672 | |
| 4x7y | SAH | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.672 | |
| 1b4v | FAD | Cholesterol oxidase | 1.1.3.6 | 0.671 | |
| 1jkf | NAD | Inositol-3-phosphate synthase | 5.5.1.4 | 0.671 | |
| 2gew | FAD | Cholesterol oxidase | 1.1.3.6 | 0.671 | |
| 3gyj | FAD | Cholesterol oxidase | 1.1.3.6 | 0.671 | |
| 4u2t | FAD | Cholesterol oxidase | 1.1.3.6 | 0.671 | |
| 5eow | FAD | 6-hydroxynicotinate 3-monooxygenase | 1.14.13.114 | 0.671 | |
| 1bc5 | SAH | Chemotaxis protein methyltransferase | 2.1.1.80 | 0.670 | |
| 1sqf | SAM | Ribosomal RNA small subunit methyltransferase B | 2.1.1.176 | 0.670 | |
| 3bg7 | FAD | Pyranose 2-oxidase | / | 0.670 | |
| 3s5w | FAD | L-ornithine N(5)-monooxygenase | / | 0.670 | |
| 4em4 | FAD | Coenzyme A disulfide reductase | / | 0.670 | |
| 3ad9 | FAD | Subunit beta of sarcosine oxidase | / | 0.669 | |
| 3lsm | SFD | Pyranose 2-oxidase | / | 0.669 | |
| 4tlx | FDA | KtzI | / | 0.669 | |
| 4tm3 | FAD | KtzI | / | 0.669 | |
| 1i3l | NAD | UDP-glucose 4-epimerase | / | 0.668 | |
| 3qgz | ADN | Histidine triad nucleotide-binding protein 1 | 3 | 0.668 | |
| 4eqg | A5A | Histidine triad nucleotide-binding protein 1 | 3 | 0.668 | |
| 1ijh | FAD | Cholesterol oxidase | 1.1.3.6 | 0.667 | |
| 1p1c | SAH | Guanidinoacetate N-methyltransferase | 2.1.1.2 | 0.667 | |
| 2px2 | SAH | Genome polyprotein | 2.7.7.48 | 0.667 | |
| 4wxx | SAH | DNA (cytosine-5)-methyltransferase 1 | 2.1.1.37 | 0.667 | |
| 1b8s | FAD | Cholesterol oxidase | 1.1.3.6 | 0.666 | |
| 3b6d | FAE | Cholesterol oxidase | 1.1.3.6 | 0.666 | |
| 3geg | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.666 | |
| 3ru9 | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.666 | |
| 3ruf | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.666 | |
| 4xcx | SAH | Small RNA 2'-O-methyltransferase | / | 0.666 | |
| 1orr | NAD | CDP-paratose 2-epimerase | / | 0.665 | |
| 3cnj | FAD | Cholesterol oxidase | 1.1.3.6 | 0.665 | |
| 3ou7 | SAM | SAM-dependent methyltransferase | / | 0.665 | |
| 4u2l | SFD | Cholesterol oxidase | 1.1.3.6 | 0.665 | |
| 1ek5 | NAD | UDP-glucose 4-epimerase | / | 0.664 | |
| 1nah | NAD | UDP-glucose 4-epimerase | 5.1.3.2 | 0.664 | |
| 2bra | FAD | [F-actin]-methionine sulfoxide oxidase MICAL1 | 1.14.13 | 0.664 | |
| 4hb9 | FAD | Uncharacterized protein | / | 0.664 | |
| 4tlz | FAD | KtzI | / | 0.664 | |
| 5dwq | SFG | Histone-arginine methyltransferase CARM1 | / | 0.664 | |
| 1f8w | FAD | NADH peroxidase | 1.11.1.1 | 0.663 | |
| 1nw3 | SAM | Histone-lysine N-methyltransferase, H3 lysine-79 specific | 2.1.1.43 | 0.663 | |
| 4eqe | KAA | Histidine triad nucleotide-binding protein 1 | 3 | 0.663 | |
| 2vyn | NAD | Glyceraldehyde-3-phosphate dehydrogenase A | / | 0.662 | |
| 3cjt | SAH | Ribosomal protein L11 methyltransferase | 2.1.1 | 0.662 | |
| 3e23 | SAM | Uncharacterized protein | / | 0.662 | |
| 3nlc | FAD | Uncharacterized protein | / | 0.662 | |
| 3v97 | SAH | Ribosomal RNA large subunit methyltransferase K/L | 2.1.1.173 | 0.662 | |
| 2bi8 | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.661 | |
| 2gvc | FAD | Thiol-specific monooxygenase | 1.14.13 | 0.661 | |
| 2hun | NAD | 336aa long hypothetical dTDP-glucose 4,6-dehydratase | / | 0.661 | |
| 4b67 | FAD | L-ornithine N(5)-monooxygenase | / | 0.661 | |
| 5icf | SAH | (S)-norcoclaurine 6-O-methyltransferase | / | 0.661 | |
| 1kph | SAH | Cyclopropane mycolic acid synthase 1 | 2.1.1.79 | 0.660 | |
| 4ek9 | EP4 | Histone-lysine N-methyltransferase, H3 lysine-79 specific | 2.1.1.43 | 0.660 | |
| 2c20 | NAD | UDP-glucose 4-epimerase | / | 0.659 | |
| 1jnr | FAD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.658 | |
| 1r00 | SAH | Aclacinomycin 10-hydroxylase RdmB | 4.1.1 | 0.658 | |
| 1rzy | 5AS | Histidine triad nucleotide-binding protein 1 | 3 | 0.658 | |
| 2c7q | SAH | Modification methylase HhaI | 2.1.1.37 | 0.658 | |
| 2oy0 | SAH | Genome polyprotein | / | 0.658 | |
| 2xyr | SFG | Replicase polyprotein 1ab | 2.1.1 | 0.658 | |
| 3cmc | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.658 | |
| 3epp | SFG | mRNA cap guanine-N7 methyltransferase | 2.1.1.56 | 0.658 | |
| 2zfu | SAH | Ribosomal RNA-processing protein 8 | / | 0.657 | |
| 3c96 | FAD | Flavin-containing monooxygenase | / | 0.657 | |
| 3e8s | SAH | Uncharacterized protein | / | 0.657 | |
| 3grr | SAH | Probable ribosomal RNA small subunit methyltransferase A | / | 0.657 | |
| 3rfx | NAD | Uronate dehydrogenase | / | 0.657 | |
| 3uka | FAD | UDP-galactopyranose mutase | / | 0.657 | |
| 4pne | SAH | Methyltransferase-like protein | / | 0.657 | |
| 4u8p | FDA | UDP-galactopyranose mutase | / | 0.657 | |
| 5il2 | SAH | N6-adenosine-methyltransferase 70 kDa subunit | / | 0.657 | |
| 1boo | SAH | Modification methylase PvuII | 2.1.1.113 | 0.656 | |
| 1kvr | NAD | UDP-glucose 4-epimerase | 5.1.3.2 | 0.656 | |
| 2c4c | FAD | [F-actin]-methionine sulfoxide oxidase MICAL1 | 1.14.13 | 0.656 | |
| 2wdz | NAD | Galactitol dehydrogenase | / | 0.656 | |
| 3all | FAD | 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase | / | 0.656 | |
| 3cty | FAD | Probable thioredoxin reductase | / | 0.656 | |
| 3nwb | 659 | Catechol O-methyltransferase | 2.1.1.6 | 0.656 | |
| 4j4b | NAI | Uncharacterized protein | / | 0.656 | |
| 4u8i | FDA | UDP-galactopyranose mutase | / | 0.656 | |
| 1qaq | SFG | rRNA adenine N-6-methyltransferase | 2.1.1.184 | 0.655 | |
| 3hja | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.655 | |
| 3ndr | NAD | Pyridoxal 4-dehydrogenase | 1.1.1.107 | 0.655 | |
| 3t7s | SAM | Uncharacterized protein | / | 0.655 | |
| 4g56 | SAH | Protein arginine N-methyltransferase 5 | / | 0.655 | |
| 1i8t | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.654 | |
| 1v59 | NAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.654 | |
| 3pl8 | FAD | Pyranose 2-oxidase | / | 0.654 | |
| 4azw | SAM | O-antigen chain terminator bifunctional methyltransferase/kinase WbdD | / | 0.654 | |
| 4kvz | SAH | PtnL protein | / | 0.654 | |
| 5e72 | SAM | N2, N2-dimethylguanosine tRNA methyltransferase | / | 0.654 | |
| 1e1m | FAD | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.653 | |
| 1i9g | SAM | tRNA (adenine(58)-N(1))-methyltransferase TrmI | / | 0.653 | |
| 1xdu | SFG | Aclacinomycin 10-hydroxylase RdmB | 4.1.1 | 0.653 | |
| 2igo | FAD | Pyranose 2-oxidase | / | 0.653 | |
| 2jib | ADP | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.653 | |
| 2yqz | SAM | Uncharacterized protein | / | 0.653 | |
| 2zif | SAM | Methyltransferase | / | 0.653 | |
| 3alj | FAD | 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase | / | 0.653 | |
| 3bwc | SAM | Spermidine synthase, putative | / | 0.653 | |
| 3hvk | 719 | Catechol O-methyltransferase | 2.1.1.6 | 0.653 | |
| 3kkz | SAM | Uncharacterized protein | / | 0.653 | |
| 4b64 | FAD | L-ornithine N(5)-monooxygenase | / | 0.653 | |
| 4fx9 | FAD | Coenzyme A disulfide reductase | 1.8.1.14 | 0.653 | |
| 7mht | SAH | Modification methylase HhaI | 2.1.1.37 | 0.653 | |
| 3ics | ADP | Coenzyme A disulfide reductase | / | 0.652 | |
| 4k2x | FAD | Polyketide oxygenase/hydroxylase | / | 0.652 | |
| 5eku | SAH | Arginine N-methyltransferase, putative | / | 0.652 | |
| 1aqi | SAH | Modification methylase TaqI | 2.1.1.72 | 0.651 | |
| 1rp0 | AHZ | Thiamine thiazole synthase, chloroplastic | / | 0.651 | |
| 2z6u | SAH | Modification methylase HhaI | 2.1.1.37 | 0.651 | |
| 2zwa | SAH | tRNA wybutosine-synthesizing protein 4 | 2.1.1.290 | 0.651 | |
| 5fa5 | MTA | Protein arginine N-methyltransferase 5 | / | 0.651 | |
| 1h83 | FAD | Polyamine oxidase | 1.5.3.14 | 0.650 | |
| 2i0z | FAD | NAD(FAD)-utilizing dehydrogenases | / | 0.650 | |
| 3k4c | FAD | Pyranose 2-oxidase | / | 0.650 | |
| 3sgl | SAM | tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC | / | 0.650 | |
| 4p8r | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.650 |