sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Modes are compared using Grim.
For more information, please see the following publication:
Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3tsc | NAD | Uncharacterized protein |
| PDB ID | HET | Uniprot Name | EC Number | Binding Mode Similarity |
Align |
|---|---|---|---|---|---|
| 3tsc | NAD | Uncharacterized protein | / | 1.442 | |
| 3pgx | NAD | Uncharacterized NAD-dependent oxidoreductase MAP_4146 | / | 1.296 | |
| 3s55 | NAD | Putative short-chain dehydrogenase/reductase | / | 1.231 | |
| 3sx2 | NAD | Uncharacterized protein | / | 1.136 | |
| 5ig2 | NAD | Short-chain dehydrogenase/reductase SDR | / | 1.051 | |
| 1nff | NAD | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.961 | |
| 2dkn | NAI | 3-alpha-hydroxysteroid dehydrogenase | / | 0.927 | |
| 4z3d | NDP | Carbonyl reductase [NADPH] 1 | 1.1.1.184 | 0.912 | |
| 1e3w | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.911 | |
| 4yag | NAI | C alpha-dehydrogenase | / | 0.909 | |
| 3l77 | NJP | Short-chain alcohol dehydrogenase | / | 0.905 | |
| 2q1w | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.896 | |
| 4is3 | NAD | 3alpha-hydroxy bile acid-CoA-ester 3-dehydrogenase 2 | 1.17.98.1 | 0.888 | |
| 1xg5 | NAP | Dehydrogenase/reductase SDR family member 11 | / | 0.886 | |
| 3qrw | NDP | Putative ketoacyl reductase | 1.3.1 | 0.886 | |
| 3ruf | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.882 | |
| 4j7x | NAP | Sepiapterin reductase | 1.1.1.153 | 0.874 | |
| 5js6 | NAD | 17-beta-hydroxysteroid dehydrogenase 14 | 1.1.1 | 0.873 | |
| 3ruc | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.869 | |
| 1kvr | NAD | UDP-glucose 4-epimerase | 5.1.3.2 | 0.860 | |
| 3geg | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.859 | |
| 1nah | NAD | UDP-glucose 4-epimerase | 5.1.3.2 | 0.857 | |
| 4yai | NAI | C alpha-dehydrogenase | / | 0.857 | |
| 5jsf | NAD | 17-beta-hydroxysteroid dehydrogenase 14 | 1.1.1 | 0.853 | |
| 1e6w | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.852 | |
| 1nfr | NAD | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.848 | |
| 3ru9 | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.848 | |
| 3tn7 | NJP | Short-chain alcohol dehydrogenase | / | 0.848 | |
| 4nbt | NAD | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.848 | |
| 3o26 | NDP | Salutaridine reductase | / | 0.844 | |
| 2gdz | NAD | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | 1.1.1.141 | 0.843 | |
| 3bhi | NAP | Carbonyl reductase [NADPH] 1 | 1.1.1.184 | 0.842 | |
| 1fdu | NAP | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.841 | |
| 4fj1 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.841 | |
| 4bmv | NAP | Short-chain dehydrogenase | / | 0.839 | |
| 3rua | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.838 | |
| 1iy8 | NAD | Levodione reductase | / | 0.837 | |
| 4b79 | NAD | Probable short-chain dehydrogenase | / | 0.836 | |
| 3w8f | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.832 | |
| 2jah | NDP | Clavaldehyde dehydrogenase | / | 0.831 | |
| 2o23 | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.828 | |
| 3rj5 | NAD | Alcohol dehydrogenase | 1.1.1.1 | 0.827 | |
| 4fn4 | NAD | Short chain dehydrogenase | / | 0.827 | |
| 4nbu | NAI | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.825 | |
| 3a28 | NAD | L-2,3-butanediol dehydrogenase | 1.1.1.76 | 0.823 | |
| 4dc1 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.823 | |
| 2q1t | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.822 | |
| 3nug | NAD | Pyridoxal 4-dehydrogenase | 1.1.1.107 | 0.822 | |
| 1e3s | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.821 | |
| 4j7u | NAP | Sepiapterin reductase | 1.1.1.153 | 0.821 | |
| 4o0l | NDP | NADPH-dependent 3-quinuclidinone reductase | / | 0.820 | |
| 2c59 | NAD | GDP-mannose 3,5-epimerase | 5.1.3.18 | 0.819 | |
| 2ztm | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.819 | |
| 3p19 | NDP | Putative blue fluorescent protein | / | 0.819 | |
| 4gh5 | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.819 | |
| 2c54 | NAD | GDP-mannose 3,5-epimerase | 5.1.3.18 | 0.813 | |
| 2p5y | NAD | UDP-glucose 4-epimerase | / | 0.813 | |
| 3sju | NDP | Keto reductase | / | 0.813 | |
| 3lu1 | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.811 | |
| 5jla | NAD | Putative short-chain dehydrogenase/reductase | / | 0.811 | |
| 3ak4 | NAD | NADH-dependent quinuclidinone reductase | / | 0.810 | |
| 4fj2 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.810 | |
| 1edo | NAP | 3-oxoacyl-[acyl-carrier-protein] reductase 1, chloroplastic | 1.1.1.100 | 0.807 | |
| 4cql | NAD | Estradiol 17-beta-dehydrogenase 8 | 1.1.1.62 | 0.807 | |
| 1oaa | NAP | Sepiapterin reductase | 1.1.1.153 | 0.805 | |
| 2ztl | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.804 | |
| 1n5d | NDP | Carbonyl reductase [NADPH] 1 | / | 0.802 | |
| 2d1y | NAD | Oxidoreductase, short-chain dehydrogenase/reductase family | / | 0.801 | |
| 2wsb | NAD | Galactitol dehydrogenase | / | 0.799 | |
| 1zem | NAD | Xylitol dehydrogenase | / | 0.792 | |
| 4kwh | NAP | Reductase homolog | / | 0.792 | |
| 2q2v | NAD | Beta-D-hydroxybutyrate dehydrogenase | / | 0.791 | |
| 3qwf | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.791 | |
| 1cyd | NDP | Carbonyl reductase [NADPH] 2 | 1.1.1.184 | 0.790 | |
| 3rud | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.789 | |
| 3vdq | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.788 | |
| 3d3w | NAP | L-xylulose reductase | 1.1.1.10 | 0.786 | |
| 3wds | NAD | NADH-dependent quinuclidinone reductase | / | 0.786 | |
| 3w8d | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.783 | |
| 1pr9 | NAP | L-xylulose reductase | 1.1.1.10 | 0.782 | |
| 3ndr | NAD | Pyridoxal 4-dehydrogenase | 1.1.1.107 | 0.782 | |
| 3rj9 | NAD | Alcohol dehydrogenase | 1.1.1.1 | 0.782 | |
| 3ru7 | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.781 | |
| 1geg | NAD | Diacetyl reductase [(S)-acetoin forming] | 1.1.1.304 | 0.780 | |
| 3w8e | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.780 | |
| 3rku | NAP | NADP-dependent 3-hydroxy acid dehydrogenase | / | 0.779 | |
| 3ruh | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.778 | |
| 4dc0 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.778 | |
| 2wdz | NAD | Galactitol dehydrogenase | / | 0.777 | |
| 2y99 | NAD | Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase | 1.3.1.56 | 0.775 | |
| 3iah | NAP | Putative oxoacyl-(Acyl carrier protein) reductase | / | 0.774 | |
| 1u7t | TDT | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.773 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.772 | |
| 1g0n | NDP | Tetrahydroxynaphthalene reductase | 1.1.1.252 | 0.770 | |
| 3gy0 | NAP | NAD(P)-dependent oxidoreductase | / | 0.770 | |
| 1orr | NAD | CDP-paratose 2-epimerase | / | 0.769 | |
| 3o03 | NAP | Dehydrogenase with different specificities (Related to short-chain alcohol dehydrogenase) | / | 0.765 | |
| 4qec | NAP | ElxO | / | 0.764 | |
| 1b15 | NAE | Alcohol dehydrogenase | 1.1.1.1 | 0.762 | |
| 1ipe | NDP | Tropinone reductase 2 | 1.1.1.236 | 0.762 | |
| 4rf2 | NAP | NADPH dependent R-specific alcohol dehydrogenase | / | 0.762 | |
| 4hp8 | NAP | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.760 | |
| 4lis | NAD | UDP-glucose 4-epimerase (Eurofung) | / | 0.760 | |
| 3ai3 | NDP | NADPH-sorbose reductase | / | 0.759 | |
| 3icp | NAD | NAD-dependent epimerase/dehydratase | / | 0.759 | |
| 3tox | NAP | Putative oxidoreductase | / | 0.759 | |
| 1w4z | NAP | Putative ketoacyl reductase | 1.3.1 | 0.757 | |
| 1xkq | NDP | Uncharacterized protein | / | 0.757 | |
| 5idw | NAP | Short-chain dehydrogenase/reductase SDR | / | 0.757 | |
| 2bd0 | NAP | Sepiapterin reductase | / | 0.754 | |
| 3r3s | NAD | Putative oxidoreductase | / | 0.754 | |
| 3o4r | NAP | Dehydrogenase/reductase SDR family member 4 | 1.1.1.184 | 0.752 | |
| 4hwk | NAP | Sepiapterin reductase | 1.1.1.153 | 0.750 | |
| 2hmv | ADP | Ktr system potassium uptake protein A | / | 0.749 | |
| 1mg5 | NAI | Alcohol dehydrogenase | 1.1.1.1 | 0.748 | |
| 3ijr | NAD | Oxidoreductase, short chain dehydrogenase/reductase family | / | 0.748 | |
| 1rkx | NAD | CDP-D-glucose-4,6-dehydratase | / | 0.747 | |
| 2c29 | NAP | Dihydroflavonol 4-reductase | / | 0.745 | |
| 1h83 | FAD | Polyamine oxidase | 1.5.3.14 | 0.744 | |
| 3uxy | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.743 | |
| 2pzj | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.741 | |
| 1sny | NAP | LD36273p | / | 0.740 | |
| 2b69 | NAD | UDP-glucuronic acid decarboxylase 1 | 4.1.1.35 | 0.740 | |
| 3ko8 | NAD | NAD-dependent epimerase/dehydratase | / | 0.740 | |
| 4gdp | FAD | Polyamine oxidase FMS1 | / | 0.739 | |
| 3u4c | NDP | NADPH-dependent reductase BacG | / | 0.738 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.738 | |
| 1i3l | NAD | UDP-glucose 4-epimerase | / | 0.737 | |
| 1x7h | NDP | Putative ketoacyl reductase | 1.3.1 | 0.737 | |
| 1ek5 | NAD | UDP-glucose 4-epimerase | / | 0.735 | |
| 2dte | NAI | Glucose 1-dehydrogenase related protein | / | 0.735 | |
| 2ggs | NDP | dTDP-4-dehydrorhamnose reductase | / | 0.735 | |
| 3aut | NAI | Glucose 1-dehydrogenase 4 | 1.1.1.47 | 0.735 | |
| 3aw9 | NAD | NAD-dependent epimerase/dehydratase | / | 0.734 | |
| 1vl8 | NAP | Oxidoreductase, short chain dehydrogenase/reductase family | / | 0.733 | |
| 3orf | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.733 | |
| 1u7t | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.732 | |
| 4yv2 | S4M | Spermidine synthase, putative | / | 0.732 | |
| 5jyd | NAD | Short chain dehydrogenase | / | 0.730 | |
| 1ae1 | NAP | Tropinone reductase 1 | / | 0.729 | |
| 4bms | NAP | Alclohol dehydrogenase/short-chain dehydrogenase | / | 0.728 | |
| 1bdb | NAD | Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase | / | 0.726 | |
| 2o06 | MTA | Spermidine synthase | 2.5.1.16 | 0.726 | |
| 4hbg | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | 1.1.1.100 | 0.726 | |
| 2bgm | NAJ | Secoisolariciresinol dehydrogenase | 1.1.1.331 | 0.725 | |
| 4twr | NAD | NAD binding site:NAD-dependent epimerase/dehydratase:UDP-glucose 4-epimerase | / | 0.724 | |
| 4i5e | NAP | Alclohol dehydrogenase/short-chain dehydrogenase | / | 0.722 | |
| 4yac | NAI | C alpha-dehydrogenase | / | 0.721 | |
| 3a4v | NAD | NDP-sugar epimerase | / | 0.720 | |
| 3ai2 | NDP | NADPH-sorbose reductase | / | 0.720 | |
| 3uic | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.720 | |
| 4m87 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.720 | |
| 2b4q | NAP | Rhamnolipids biosynthesis 3-oxoacyl-[acyl-carrier-protein] reductase | 1.1.1.100 | 0.719 | |
| 4fc7 | NAP | Peroxisomal 2,4-dienoyl-CoA reductase | 1.3.1.34 | 0.719 | |
| 2nnl | NAP | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.718 | |
| 4zju | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.718 | |
| 5bxy | SAH | Putative RNA methylase family UPF0020 | / | 0.718 | |
| 2h9i | EAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.717 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.717 | |
| 2jb2 | FAD | L-amino acid oxidase | / | 0.716 | |
| 1gee | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.714 | |
| 2hrb | NAP | Carbonyl reductase [NADPH] 3 | 1.1.1.184 | 0.714 | |
| 2yr4 | FAD | Phenylalanine 2-monooxygenase precursor | 1.13.12.9 | 0.714 | |
| 1nai | NAD | UDP-glucose 4-epimerase | 5.1.3.2 | 0.713 | |
| 3g49 | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.713 | |
| 3mje | NDP | AmphB | / | 0.712 | |
| 4qed | NAP | ElxO | / | 0.712 | |
| 1x7g | NAP | Putative ketoacyl reductase | 1.3.1 | 0.711 | |
| 3bgi | SAH | Thiopurine S-methyltransferase | 2.1.1.67 | 0.711 | |
| 3rue | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.711 | |
| 3wmx | NAD | NAD dependent epimerase/dehydratase | / | 0.711 | |
| 3bmo | NAP | Pteridine reductase | / | 0.710 | |
| 3uce | NDP | Dehydrogenase | / | 0.710 | |
| 4iqg | NAP | Short-chain dehydrogenase/reductase SDR | / | 0.710 | |
| 3kpf | FAD | Polyamine oxidase | 1.5.3.14 | 0.709 | |
| 4k6f | NAP | Putative Acetoacetyl-CoA reductase | / | 0.709 | |
| 4wec | NAD | Short chain dehydrogenase | / | 0.709 | |
| 1jki | NAI | Inositol-3-phosphate synthase | 5.5.1.4 | 0.708 | |
| 5cpb | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.707 | |
| 2bfo | NDP | Pteridine reductase 1 | 1.5.1.33 | 0.706 | |
| 1rwb | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.703 | |
| 4pvd | NDP | NADPH-dependent methylglyoxal reductase GRE2 | / | 0.703 | |
| 2b35 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.702 | |
| 4fp9 | SAM | 5-methylcytosine rRNA methyltransferase NSUN4 | 2.1.1 | 0.702 | |
| 2yut | NAP | Putative short-chain oxidoreductase | / | 0.701 | |
| 2ztu | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.701 | |
| 2ztv | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.700 | |
| 3sj7 | NDP | 3-oxoacyl-(Acyl-carrier-protein) reductase, putative | / | 0.700 | |
| 1gco | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.699 | |
| 2ekp | NAD | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.699 | |
| 2ag5 | NAD | 3-hydroxybutyrate dehydrogenase type 2 | / | 0.698 | |
| 2hsd | NAD | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.698 | |
| 3a4t | SFG | tRNA (cytosine(48)-C(5))-methyltransferase | 2.1.1 | 0.698 | |
| 2aqh | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.696 | |
| 4j4b | NAI | Uncharacterized protein | / | 0.695 | |
| 1fk8 | NAD | 3-alpha-hydroxysteroid dehydrogenase/carbonyl reductase | 1.1.1.50 | 0.693 | |
| 1h5q | NAP | NADP-dependent mannitol dehydrogenase | 1.1.1.138 | 0.693 | |
| 2b37 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.693 | |
| 4bqp | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.693 | |
| 5koi | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.693 | |
| 3a1n | NAD | NDP-sugar epimerase | / | 0.691 | |
| 2aqi | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.690 | |
| 2ji9 | ADP | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.689 | |
| 2idz | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.688 | |
| 2ie0 | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.688 | |
| 2zat | NAP | Dehydrogenase/reductase SDR family member 4 | 1.1.1.184 | 0.687 | |
| 2hun | NAD | 336aa long hypothetical dTDP-glucose 4,6-dehydratase | / | 0.686 | |
| 1b14 | NAD | Alcohol dehydrogenase | 1.1.1.1 | 0.685 | |
| 1w8d | NAP | 2,4-dienoyl-CoA reductase, mitochondrial | 1.3.1.34 | 0.685 | |
| 2wyv | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.685 | |
| 4oxy | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.685 | |
| 1g6k | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.684 | |
| 3go4 | SAH | Uncharacterized protein | / | 0.684 | |
| 4dmm | NAP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.684 | |
| 1ahh | NAD | 7-alpha-hydroxysteroid dehydrogenase | 1.1.1.159 | 0.682 | |
| 1g1a | NAD | dTDP-glucose 4,6-dehydratase | / | 0.682 | |
| 4c4o | NAD | SADH | / | 0.682 | |
| 1b16 | NAQ | Alcohol dehydrogenase | 1.1.1.1 | 0.679 | |
| 1wvg | APR | CDP-glucose 4,6-dehydratase | 4.2.1.45 | 0.678 | |
| 2rbe | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.678 | |
| 3dmt | NAD | Glyceraldehyde-3-phosphate dehydrogenase, glycosomal | 1.2.1.12 | 0.678 | |
| 4hxy | NDP | Plm1 | / | 0.678 | |
| 3ihg | FAD | Aklavinone 12-hydroxylase RdmE | / | 0.676 | |
| 1vjt | NAD | Alpha-glucosidase, putative | / | 0.675 | |
| 2ore | SAH | DNA adenine methylase | 2.1.1.72 | 0.675 | |
| 2yy7 | NAD | L-threonine dehydrogenase | / | 0.675 | |
| 3a9w | NAD | NDP-sugar epimerase | / | 0.675 | |
| 1xcb | NAD | Redox-sensing transcriptional repressor Rex | / | 0.674 | |
| 2p5u | NAD | UDP-glucose 4-epimerase | / | 0.674 | |
| 2ntj | P1H | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.673 | |
| 3ada | NAD | Subunit alpha of sarocosine oxidase | / | 0.673 | |
| 3jyp | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.673 | |
| 5ccx | SAH | tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A | 2.1.1.220 | 0.673 | |
| 1xse | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.672 | |
| 4bgi | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.672 | |
| 4m55 | NAD | UDP-glucuronic acid decarboxylase 1 | 4.1.1.35 | 0.672 | |
| 3zcb | ATP | Adenosine monophosphate-protein transferase VbhT | 2.7.7.n1 | 0.671 | |
| 2aqk | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.670 | |
| 2nyu | SAM | rRNA methyltransferase 2, mitochondrial | / | 0.670 | |
| 4dre | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.670 | |
| 4fj0 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.670 | |
| 2nv6 | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.669 | |
| 1vrw | NAI | Enoyl-ACP reductase | / | 0.668 | |
| 2zth | SAM | Catechol O-methyltransferase | 2.1.1.6 | 0.668 | |
| 4lk3 | NAD | UDP-glucuronic acid decarboxylase 1 | 4.1.1.35 | 0.668 | |
| 4gll | NAD | UDP-glucuronic acid decarboxylase 1 | 4.1.1.35 | 0.667 | |
| 3h4v | NAP | Pteridine reductase 1 | 1.5.1.33 | 0.666 | |
| 1boo | SAH | Modification methylase PvuII | 2.1.1.113 | 0.665 | |
| 1sby | NAD | Alcohol dehydrogenase | 1.1.1.1 | 0.664 | |
| 1rpn | NDP | GDP-mannose 4,6-dehydratase | / | 0.662 | |
| 4dti | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.662 | |
| 1i2b | NAD | UDP-sulfoquinovose synthase, chloroplastic | 3.13.1.1 | 0.661 | |
| 2bgl | NAJ | Secoisolariciresinol dehydrogenase | 1.1.1.331 | 0.661 | |
| 3k7t | FAD | 6-hydroxy-L-nicotine oxidase | / | 0.661 | |
| 2gn8 | NAP | UDP-N-acetylglucosamine 4,6-dehydratase (inverting) | 4.2.1.115 | 0.660 | |
| 3mht | SAH | Modification methylase HhaI | 2.1.1.37 | 0.660 | |
| 3rfx | NAD | Uronate dehydrogenase | / | 0.660 | |
| 4fw8 | NAI | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.660 | |
| 4jk3 | NAD | Uncharacterized protein | / | 0.660 | |
| 5lc1 | NAD | L-threonine 3-dehydrogenase | / | 0.660 | |
| 2q1u | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.659 | |
| 3f1k | NAP | Uncharacterized oxidoreductase YciK | 1 | 0.659 | |
| 4b8z | NAP | GDP-L-fucose synthase | 1.1.1.271 | 0.659 | |
| 1eny | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.658 | |
| 1zh8 | NAP | Uncharacterized protein | / | 0.658 | |
| 2nq8 | ZID | Enoyl-ACP reductase | / | 0.658 | |
| 2ntv | P1H | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.658 | |
| 4b8w | NAP | GDP-L-fucose synthase | 1.1.1.271 | 0.658 | |
| 4yr9 | NAD | L-threonine 3-dehydrogenase, mitochondrial | 1.1.1.103 | 0.658 | |
| 4wlu | NAD | Malate dehydrogenase, mitochondrial | 1.1.1.37 | 0.657 | |
| 1n2s | NAI | dTDP-4-dehydrorhamnose reductase | 1.1.1.133 | 0.656 | |
| 1npt | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.656 | |
| 3oey | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.656 | |
| 3w6u | NAP | 6-phosphogluconate dehydrogenase, NAD-binding protein | / | 0.656 | |
| 4dqu | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.656 | |
| 4j49 | NAI | Uncharacterized protein | / | 0.656 | |
| 4nbw | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.656 | |
| 2aq8 | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.655 | |
| 5jy1 | NAD | Putative short-chain dehydrogenase/reductase | / | 0.655 | |
| 4eso | NAP | Putative oxidoreductase | / | 0.654 | |
| 1rjg | SAH | Leucine carboxyl methyltransferase 1 | 2.1.1.233 | 0.653 | |
| 1uxj | NAD | Malate dehydrogenase | / | 0.653 | |
| 2dfv | NAD | L-threonine 3-dehydrogenase | / | 0.653 | |
| 3c3y | SAH | O-methyltransferase | / | 0.653 | |
| 3d64 | NAD | Adenosylhomocysteinase | / | 0.653 | |
| 4xcx | SAH | Small RNA 2'-O-methyltransferase | / | 0.653 | |
| 1b2l | NDC | Alcohol dehydrogenase | 1.1.1.1 | 0.652 | |
| 3sgl | SAM | tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC | / | 0.652 | |
| 1gd1 | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.651 | |
| 1la2 | NAD | Inositol-3-phosphate synthase | 5.5.1.4 | 0.651 | |
| 3abi | NAD | Uncharacterized protein | / | 0.651 | |
| 5l3d | FAD | Lysine-specific histone demethylase 1A | 1 | 0.651 | |
| 1emd | NAD | Malate dehydrogenase | / | 0.650 | |
| 1nbo | NAD | Glyceraldehyde-3-phosphate dehydrogenase A, chloroplastic | 1.2.1.13 | 0.650 | |
| 2vhx | NAD | Alanine dehydrogenase | 1.4.1.1 | 0.650 | |
| 3jyq | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.650 | |
| 4jnk | NAI | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.650 |