Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3ocg | OCG | Mitogen-activated protein kinase 14 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 3ocg | OCG | Mitogen-activated protein kinase 14 | / | 1.000 | |
| 4kin | 1M8 | Mitogen-activated protein kinase 14 | / | 0.594 | |
| 3mpt | 1GK | Mitogen-activated protein kinase 14 | / | 0.588 | |
| 2rg6 | 287 | Mitogen-activated protein kinase 14 | / | 0.584 | |
| 3fkl | FKL | Mitogen-activated protein kinase 14 | / | 0.575 | |
| 3iph | G11 | Mitogen-activated protein kinase 14 | / | 0.575 | |
| 4aa5 | NQB | Mitogen-activated protein kinase 14 | / | 0.574 | |
| 4kiq | 1RA | Mitogen-activated protein kinase 14 | / | 0.574 | |
| 3fln | 3FN | Mitogen-activated protein kinase 14 | / | 0.572 | |
| 3nww | 3NW | Mitogen-activated protein kinase 14 | / | 0.568 | |
| 4kip | 1R9 | Mitogen-activated protein kinase 14 | / | 0.568 | |
| 2rg5 | 279 | Mitogen-activated protein kinase 14 | / | 0.565 | |
| 2bal | PQA | Mitogen-activated protein kinase 14 | / | 0.551 | |
| 3fsk | RO6 | Mitogen-activated protein kinase 14 | / | 0.544 | |
| 3flz | FLZ | Mitogen-activated protein kinase 14 | / | 0.540 | |
| 3hl7 | I47 | Mitogen-activated protein kinase 14 | / | 0.536 | |
| 3dt1 | P40 | Mitogen-activated protein kinase 14 | / | 0.530 | |
| 3fi4 | FI4 | Mitogen-activated protein kinase 14 | / | 0.530 | |
| 3fmk | FMK | Mitogen-activated protein kinase 14 | / | 0.530 | |
| 3fmh | 533 | Mitogen-activated protein kinase 14 | / | 0.525 | |
| 3mvm | 39P | Mitogen-activated protein kinase 14 | / | 0.524 | |
| 3l8x | N4D | Mitogen-activated protein kinase 14 | / | 0.522 | |
| 4aa4 | QC0 | Mitogen-activated protein kinase 14 | / | 0.519 | |
| 3uvq | FS8 | Mitogen-activated protein kinase 14 | / | 0.514 | |
| 3b8r | 887 | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.510 | |
| 1ywr | LI9 | Mitogen-activated protein kinase 14 | / | 0.504 | |
| 2wot | ZZG | TGF-beta receptor type-1 | 2.7.11.30 | 0.503 | |
| 3mvl | 38P | Mitogen-activated protein kinase 14 | / | 0.503 | |
| 3uib | SB2 | Putative mitogen-activated protein kinase | / | 0.502 | |
| 4lop | SB4 | Mitogen-activated protein kinase 14 | / | 0.501 | |
| 3fly | FLY | Mitogen-activated protein kinase 14 | / | 0.500 | |
| 3s4q | NK0 | Mitogen-activated protein kinase 14 | / | 0.500 | |
| 3el8 | PD5 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.499 | |
| 3bbt | FMM | Receptor tyrosine-protein kinase erbB-4 | 2.7.10.1 | 0.496 | |
| 3flw | FLW | Mitogen-activated protein kinase 14 | / | 0.496 | |
| 3gfe | P37 | Mitogen-activated protein kinase 14 | / | 0.495 | |
| 4eh6 | 0ON | Mitogen-activated protein kinase 14 | / | 0.494 | |
| 2zb0 | GK3 | Mitogen-activated protein kinase 14 | / | 0.493 | |
| 3b2w | 9NH | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.492 | |
| 4dgg | I76 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.492 | |
| 2og8 | 1N8 | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.490 | |
| 3hdm | MMG | Serine/threonine-protein kinase Sgk1 | 2.7.11.1 | 0.488 | |
| 4y95 | 746 | Tyrosine-protein kinase | / | 0.488 | |
| 1zz2 | B11 | Mitogen-activated protein kinase 14 | / | 0.487 | |
| 2chx | 090 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.487 | |
| 3mpa | SB2 | Mitogen-activated protein kinase 14 | / | 0.487 | |
| 4loo | SB4 | Mitogen-activated protein kinase 14 | / | 0.487 | |
| 2bdj | HET | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.485 | |
| 3vs6 | VSH | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.485 | |
| 2hen | ADP | Ephrin type-B receptor 2 | 2.7.10.1 | 0.484 | |
| 2qo9 | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.483 | |
| 3hll | I45 | Mitogen-activated protein kinase 14 | / | 0.482 | |
| 4gk3 | L87 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.482 | |
| 2ghl | LIB | Mitogen-activated protein kinase 14 | / | 0.481 | |
| 3hvc | GG5 | Mitogen-activated protein kinase 14 | / | 0.481 | |
| 4g2f | C07 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.480 | |
| 2qd9 | LGF | Mitogen-activated protein kinase 14 | / | 0.479 | |
| 3oaf | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.479 | |
| 3ac2 | KSE | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.478 | |
| 2dq7 | STU | Tyrosine-protein kinase Fyn | 2.7.10.2 | 0.477 | |
| 3hx4 | ANP | Calmodulin-domain protein kinase 1 | / | 0.477 | |
| 2p2h | 994 | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.476 | |
| 2y6o | 1N1 | Ephrin type-A receptor 4 | 2.7.10.1 | 0.476 | |
| 3gc9 | B45 | Mitogen-activated protein kinase 11 | 2.7.11.24 | 0.476 | |
| 1c2t | NHS | Phosphoribosylglycinamide formyltransferase | / | 0.475 | |
| 1y57 | MPZ | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.475 | |
| 1zyj | BI5 | Mitogen-activated protein kinase 14 | / | 0.475 | |
| 2xyu | Q9G | Ephrin type-A receptor 4 | 2.7.10.1 | 0.475 | |
| 3gub | GUB | Death-associated protein kinase 1 | 2.7.11.1 | 0.475 | |
| 2itn | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.474 | |
| 3zuy | TCH | Transporter | / | 0.473 | |
| 3uyt | 0CK | Casein kinase I isoform delta | 2.7.11.1 | 0.471 | |
| 3w2r | W2R | Epidermal growth factor receptor | 2.7.10.1 | 0.471 | |
| 2c0o | L2G | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.470 | |
| 2nry | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.470 | |
| 3w33 | W19 | Epidermal growth factor receptor | 2.7.10.1 | 0.470 | |
| 4uyf | 73B | Bromodomain-containing protein 2 | / | 0.470 | |
| 1zem | NAD | Xylitol dehydrogenase | / | 0.469 | |
| 1c2t | GAR | Phosphoribosylglycinamide formyltransferase | / | 0.468 | |
| 4c02 | TAK | Activin receptor type-1 | 2.7.11.30 | 0.468 | |
| 4h4z | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.468 | |
| 4i23 | 1C9 | Epidermal growth factor receptor | 2.7.10.1 | 0.468 | |
| 1h73 | ANP | Homoserine kinase | 2.7.1.39 | 0.467 | |
| 2o0u | C0M | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.467 | |
| 2qoc | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.467 | |
| 3ac1 | KZI | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.467 | |
| 1mg5 | NAI | Alcohol dehydrogenase | 1.1.1.1 | 0.466 | |
| 3lmg | ANP | Receptor tyrosine-protein kinase erbB-3 | 2.7.10.1 | 0.466 | |
| 3vrz | VRZ | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.466 | |
| 4c8b | 0LI | Receptor-interacting serine/threonine-protein kinase 2 | 2.7.11.1 | 0.466 | |
| 4fuy | EK2 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.466 | |
| 4y3z | F41 | Endothiapepsin | 3.4.23.22 | 0.466 | |
| 3vjo | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.465 | |
| 4bb4 | 32W | Ephrin type-B receptor 4 | 2.7.10.1 | 0.465 | |
| 4bdc | ODH | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.465 | |
| 2qd3 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.464 | |
| 2r5t | ANP | Serine/threonine-protein kinase Sgk1 | 2.7.11.1 | 0.464 | |
| 3ac3 | KSH | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.464 | |
| 3uvp | 048 | Mitogen-activated protein kinase 14 | / | 0.464 | |
| 4mxo | DB8 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.464 | |
| 2itu | ITQ | Epidermal growth factor receptor | 2.7.10.1 | 0.463 | |
| 2wou | ZZF | TGF-beta receptor type-1 | 2.7.11.30 | 0.463 | |
| 2nru | T12 | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.462 | |
| 2of4 | 979 | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.462 | |
| 3t7x | 4SH | Endothiapepsin | 3.4.23.22 | 0.462 | |
| 4id7 | 1G0 | Activated CDC42 kinase 1 | / | 0.462 | |
| 1e3e | NAI | Alcohol dehydrogenase 4 | 1.1.1.1 | 0.461 | |
| 3ndr | NAD | Pyridoxal 4-dehydrogenase | 1.1.1.107 | 0.461 | |
| 5ikr | ID8 | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.461 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.460 | |
| 2ooy | ATP | 5'-AMP-activated protein kinase subunit gamma | / | 0.460 | |
| 1qpd | STU | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.459 | |
| 2gs7 | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.459 | |
| 2ivv | PP1 | Proto-oncogene tyrosine-protein kinase receptor Ret | 2.7.10.1 | 0.459 | |
| 3cuk | FAD | D-amino-acid oxidase | 1.4.3.3 | 0.459 | |
| 3e8n | VRA | Dual specificity mitogen-activated protein kinase kinase 1 | 2.7.12.2 | 0.459 | |
| 3vid | 4TT | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.459 | |
| 4hbg | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | 1.1.1.100 | 0.459 | |
| 4i22 | IRE | Epidermal growth factor receptor | 2.7.10.1 | 0.459 | |
| 4mxx | DB8 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.459 | |
| 5bvw | 1N1 | Epithelial discoidin domain-containing receptor 1 | 2.7.10.1 | 0.459 | |
| 1c3e | GAR | Phosphoribosylglycinamide formyltransferase | / | 0.458 | |
| 1m17 | AQ4 | Epidermal growth factor receptor | 2.7.10.1 | 0.458 | |
| 2vd5 | BI8 | Myotonin-protein kinase | 2.7.11.1 | 0.458 | |
| 2ww4 | ADP | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | 2.7.1.148 | 0.458 | |
| 4anx | 534 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.458 | |
| 4b99 | R4L | Mitogen-activated protein kinase 7 | 2.7.11.24 | 0.458 | |
| 5e8w | STU | TGF-beta receptor type-1 | 2.7.11.30 | 0.458 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.457 | |
| 3f5p | 741 | Insulin-like growth factor 1 receptor | 2.7.10.1 | 0.457 | |
| 3roc | 29A | Mitogen-activated protein kinase 14 | / | 0.457 | |
| 3vry | B43 | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.457 | |
| 2j3j | HC4 | NADPH-dependent oxidoreductase 2-alkenal reductase | 1.3.1.74 | 0.456 | |
| 2yit | YIT | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.456 | |
| 2zva | 1N1 | Tyrosine-protein kinase Lyn | 2.7.10.2 | 0.456 | |
| 3inv | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.456 | |
| 4gk2 | L66 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.456 | |
| 4is3 | NAD | 3alpha-hydroxy bile acid-CoA-ester 3-dehydrogenase 2 | 1.17.98.1 | 0.456 | |
| 4xli | 1N1 | Abelson tyrosine-protein kinase 2 | 2.7.10.2 | 0.456 | |
| 2e9u | A25 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.455 | |
| 2hk5 | 1BM | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.455 | |
| 2of2 | 547 | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.455 | |
| 3bv3 | P39 | Mitogen-activated protein kinase 14 | / | 0.455 | |
| 4c3f | 7KW | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.455 | |
| 4fic | 0UL | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.455 | |
| 4y93 | 746 | Tyrosine-protein kinase | / | 0.455 | |
| 1di9 | MSQ | Mitogen-activated protein kinase 14 | / | 0.454 | |
| 1szm | BI4 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.454 | |
| 1trb | FAD | Thioredoxin reductase | 1.8.1.9 | 0.454 | |
| 1yol | S03 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.454 | |
| 2acx | ANP | G protein-coupled receptor kinase 6 | 2.7.11.16 | 0.454 | |
| 4e73 | 0NR | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.454 | |
| 4gt3 | ATP | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.454 | |
| 4kb8 | 1QO | Casein kinase I isoform delta | 2.7.11.1 | 0.454 | |
| 4m69 | ANP | Receptor-interacting serine/threonine-protein kinase 3 | 2.7.11.1 | 0.454 | |
| 1nvq | UCN | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.453 | |
| 1rrm | APR | Lactaldehyde reductase | 1.1.1.77 | 0.453 | |
| 2c0t | L3G | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.453 | |
| 2zb1 | GK4 | Mitogen-activated protein kinase 14 | / | 0.453 | |
| 3b70 | NAP | Enoyl reductase LovC | 1 | 0.453 | |
| 2hk9 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.452 | |
| 2x8e | X8E | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.452 | |
| 2zv9 | PP2 | Tyrosine-protein kinase Lyn | 2.7.10.2 | 0.452 | |
| 3gu8 | 3GU | Death-associated protein kinase 1 | 2.7.11.1 | 0.452 | |
| 3v04 | V04 | Dual specificity mitogen-activated protein kinase kinase 1 | 2.7.12.2 | 0.452 | |
| 4fv0 | EK3 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.452 | |
| 4tuv | CPZ | Cytochrome P450 119 | 1.14 | 0.452 | |
| 1cde | GAR | Phosphoribosylglycinamide formyltransferase | / | 0.451 | |
| 2bri | ANP | Uridylate kinase | 2.7.4.22 | 0.451 | |
| 2itw | ITQ | Epidermal growth factor receptor | 2.7.10.1 | 0.451 | |
| 2p9c | NAI | D-3-phosphoglycerate dehydrogenase | 1.1.1.95 | 0.451 | |
| 3axw | TID | Casein kinase II subunit alpha | 2.7.11.1 | 0.451 | |
| 3cjf | SAV | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.451 | |
| 3d7z | GK5 | Mitogen-activated protein kinase 14 | / | 0.451 | |
| 3owj | 1EL | Casein kinase II subunit alpha | 2.7.11.1 | 0.451 | |
| 3pi0 | F91 | Endothiapepsin | 3.4.23.22 | 0.451 | |
| 3r3s | NAD | Putative oxidoreductase | / | 0.451 | |
| 4hjo | AQ4 | Epidermal growth factor receptor | 2.7.10.1 | 0.451 | |
| 4i6a | HMG | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 1.1.1.88 | 0.451 | |
| 4ien | COA | Putative acyl-CoA hydrolase | / | 0.451 | |
| 4jr3 | KJR | Epidermal growth factor receptor | 2.7.10.1 | 0.451 | |
| 4yuq | KS1 | Calmodulin-like domain protein kinase | / | 0.451 | |
| 1pnv | TYD | dTDP-epi-vancosaminyltransferase | 2.4.1.311 | 0.450 | |
| 1rbz | KT5 | Trifunctional purine biosynthetic protein adenosine-3 | 2.1.2.2 | 0.450 | |
| 2g82 | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.450 | |
| 2oor | NAD | NAD(P) transhydrogenase subunit alpha part 1 | 1.6.1.2 | 0.450 | |
| 2q61 | SF1 | Peroxisome proliferator-activated receptor gamma | / | 0.450 | |
| 3b8q | 900 | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.450 | |
| 3cis | ATP | Universal stress protein Rv2623 | / | 0.450 | |
| 3nug | NAD | Pyridoxal 4-dehydrogenase | 1.1.1.107 | 0.450 | |
| 3pvu | QRW | Beta-adrenergic receptor kinase 1 | 2.7.11.15 | 0.450 | |
| 3sp6 | IL2 | Peroxisome proliferator-activated receptor alpha | / | 0.450 | |
| 3ump | ATP | ATP-dependent 6-phosphofructokinase isozyme 2 | 2.7.1.11 | 0.450 | |
| 4d9t | 0JG | Ribosomal protein S6 kinase alpha-3 | 2.7.11.1 | 0.450 | |
| 4hle | 17V | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.450 | |
| 4jq7 | KJQ | Epidermal growth factor receptor | 2.7.10.1 | 0.450 | |
| 4jvf | 17X | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.450 | |
| 4l2i | FAD | Electron transfer flavoprotein alpha/beta-subunit | / | 0.450 | |
| 1c1d | NAI | Phenylalanine dehydrogenase | / | 0.449 | |
| 2vwy | 7X5 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.449 | |
| 2yn8 | STU | Ephrin type-B receptor 4 | 2.7.10.1 | 0.449 | |
| 3ac5 | KZM | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.449 | |
| 4fc7 | NAP | Peroxisomal 2,4-dienoyl-CoA reductase | 1.3.1.34 | 0.449 | |
| 4k11 | 0J9 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.449 | |
| 4ku5 | DCC | 3-oxoacyl-[ACP] synthase III | / | 0.449 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.449 | |
| 4riy | ANP | Receptor tyrosine-protein kinase erbB-3 | 2.7.10.1 | 0.449 | |
| 5ar4 | SB2 | Receptor-interacting serine/threonine-protein kinase 2 | 2.7.11.1 | 0.449 | |
| 5ez7 | FAD | Probable FAD-dependent oxidoreductase PA4991 | / | 0.449 | |
| 2vwx | 7X4 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.448 | |
| 3cbl | STU | Tyrosine-protein kinase Fes/Fps | 2.7.10.2 | 0.448 | |
| 3f69 | XDR | Serine/threonine-protein kinase PknB | 2.7.11.1 | 0.448 | |
| 3lfb | Z87 | Mitogen-activated protein kinase 14 | / | 0.448 | |
| 3pbz | F02 | Endothiapepsin | 3.4.23.22 | 0.448 | |
| 3poz | 03P | Epidermal growth factor receptor | 2.7.10.1 | 0.448 | |
| 4mq2 | 2C4 | Dual specificity tyrosine-phosphorylation-regulated kinase 1A | 2.7.12.1 | 0.448 | |
| 1ae1 | NAP | Tropinone reductase 1 | / | 0.447 | |
| 1cde | DZF | Phosphoribosylglycinamide formyltransferase | / | 0.447 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.447 | |
| 2a1o | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.447 | |
| 2itq | ITQ | Epidermal growth factor receptor | 2.7.10.1 | 0.447 | |
| 2vx0 | 7X7 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.447 | |
| 3evc | SAH | Genome polyprotein | 2.1.1.56 | 0.447 | |
| 3ns2 | PYV | Abscisic acid receptor PYL2 | / | 0.447 | |
| 4h4u | NDP | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.447 | |
| 1a72 | PAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.446 | |
| 1joa | FAD | NADH peroxidase | 1.11.1.1 | 0.446 | |
| 1qrp | HH0 | Pepsin A-4 | 3.4.23.1 | 0.446 | |
| 1uu7 | BI2 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.446 | |
| 1ywn | LIF | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.446 | |
| 2bdf | 24A | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.446 | |
| 2eb3 | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.446 | |
| 2hsd | NAD | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.446 | |
| 3nbw | TR4 | Ketohexokinase | / | 0.446 | |
| 3nj0 | PYV | Abscisic acid receptor PYL2 | / | 0.446 | |
| 3nxx | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 3pvw | QRX | Beta-adrenergic receptor kinase 1 | 2.7.11.15 | 0.446 | |
| 3vs4 | VSF | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.446 | |
| 4eev | L1X | Hepatocyte growth factor receptor | 2.7.10.1 | 0.446 | |
| 4loq | SB4 | Mitogen-activated protein kinase 14 | / | 0.446 | |
| 4m6j | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 4rrw | LUR | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.446 | |
| 4rrz | LUR | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.446 | |
| 1k6t | XN1 | Gag-Pol polyprotein | 3.4.23.16 | 0.445 | |
| 1me8 | RVP | Inosine-5'-monophosphate dehydrogenase | / | 0.445 | |
| 2itz | IRE | Epidermal growth factor receptor | 2.7.10.1 | 0.445 | |
| 3r83 | Z14 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.445 | |
| 3s79 | ASD | Aromatase | 1.14.14.14 | 0.445 | |
| 4fv7 | E94 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.445 | |
| 4lsm | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.445 | |
| 4mwh | ATP | Casein kinase II subunit alpha | 2.7.11.1 | 0.445 | |
| 4xq9 | NAD | Homospermidine synthase | 2.5.1.44 | 0.445 | |
| 5hes | 032 | Mitogen-activated protein kinase kinase kinase 20 | 2.7.11.25 | 0.445 | |
| 1fnn | ADP | ORC1-type DNA replication protein | / | 0.444 | |
| 1hnc | GDN | Glutathione S-transferase Mu 2 | 2.5.1.18 | 0.444 | |
| 1pn3 | TYD | dTDP-epi-vancosaminyltransferase | 2.4.1.311 | 0.444 | |
| 1rfv | ADP | Pyridoxal kinase | 2.7.1.35 | 0.444 | |
| 1w06 | W05 | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
| 2nr4 | FMN | Conserved protein | / | 0.444 | |
| 3ad6 | KSC | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.444 | |
| 3pll | F06 | Endothiapepsin | 3.4.23.22 | 0.444 | |
| 4bdh | WVI | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.444 | |
| 4g6n | EK0 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.444 | |
| 4h95 | 06U | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 1orr | NAD | CDP-paratose 2-epimerase | / | 0.443 | |
| 1xkk | FMM | Epidermal growth factor receptor | 2.7.10.1 | 0.443 | |
| 2cgw | 3C3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.443 | |
| 2fb8 | 215 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.443 | |
| 2itv | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.443 | |
| 2nmt | NHM | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.443 | |
| 2qoq | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.443 | |
| 2wmt | ZYT | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.443 | |
| 2yyu | C5P | Orotidine 5'-phosphate decarboxylase | / | 0.443 | |
| 2zjm | F1M | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 3elu | SAM | Methyltransferase | / | 0.443 | |
| 3ggg | NAD | Prephenate dehydrogenase | / | 0.443 | |
| 3qlf | PD5 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.443 | |
| 3zk5 | Z18 | Cytochrome P450 monooxygenase PikC | / | 0.443 | |
| 4ewn | 0VR | Imidazole glycerol phosphate synthase subunit HisF | 4.1.3 | 0.443 | |
| 4nka | 2K7 | Fibroblast growth factor receptor 1 | / | 0.443 | |
| 5e8x | STU | TGF-beta receptor type-1 | 2.7.11.30 | 0.443 | |
| 1a7k | NAD | Glyceraldehyde-3-phosphate dehydrogenase, glycosomal | 1.2.1.12 | 0.442 | |
| 1dz6 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
| 2cdu | FAD | NADH oxidase | / | 0.442 | |
| 2ekp | NAD | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.442 | |
| 2gfs | PQB | Mitogen-activated protein kinase 14 | / | 0.442 | |
| 2h2q | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.442 | |
| 2i5b | ADP | Pyridoxine kinase | / | 0.442 | |
| 2oiq | STI | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.442 | |
| 2wmq | ZYQ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.442 | |
| 2yxu | ATP | Pyridoxal kinase | 2.7.1.35 | 0.442 | |
| 3dey | DHT | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.442 | |
| 3klm | DHT | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.442 | |
| 3q92 | XNB | Ketohexokinase | / | 0.442 | |
| 3vrt | YS2 | Vitamin D3 receptor | / | 0.442 | |
| 4ic7 | ANP | Mitogen-activated protein kinase 7 | 2.7.11.24 | 0.442 | |
| 4ie6 | UN9 | Alpha-ketoglutarate-dependent dioxygenase FTO | / | 0.442 | |
| 1ai9 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 1e8x | ATP | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.441 | |
| 1npt | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.441 | |
| 1qvn | FRI | Interleukin-2 | / | 0.441 | |
| 2cen | 4AH | Protease | / | 0.441 | |
| 2ch6 | ADP | N-acetyl-D-glucosamine kinase | 2.7.1.59 | 0.441 | |
| 2e9n | 76A | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.441 | |
| 2exc | JNK | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.441 | |
| 2h8h | H8H | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.441 | |
| 2hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.441 | |
| 2i4x | KGQ | Protease | / | 0.441 | |
| 2qo7 | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.441 | |
| 2vwz | 7X6 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.441 | |
| 3cls | FAD | Electron transfer flavoprotein subunit alpha | / | 0.441 | |
| 3cz7 | ACO | Histone acetyltransferase RTT109 | 2.3.1.48 | 0.441 | |
| 3dga | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.441 | |
| 3mwu | BK3 | Calmodulin-domain protein kinase 1, putative | / | 0.441 | |
| 3ogq | AB1 | Pol polyprotein | / | 0.441 | |
| 4a31 | 2CB | Glycylpeptide N-tetradecanoyltransferase | / | 0.441 | |
| 4bdf | H3R | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.441 | |
| 5lc1 | NAD | L-threonine 3-dehydrogenase | / | 0.441 | |
| 1gqt | ACP | Ribokinase | / | 0.440 | |
| 1hdc | CBO | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.440 | |
| 1i7g | AZ2 | Peroxisome proliferator-activated receptor alpha | / | 0.440 | |
| 1zrz | BI1 | Protein kinase C iota type | 2.7.11.13 | 0.440 | |
| 2cdz | 23D | Serine/threonine-protein kinase PAK 4 | 2.7.11.1 | 0.440 | |
| 2oo5 | TXD | NAD(P) transhydrogenase subunit alpha part 1 | 1.6.1.2 | 0.440 | |
| 2vwu | 7X1 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.440 | |
| 2w0j | ZAT | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.440 | |
| 2xck | MH4 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.440 | |
| 3bv2 | P38 | Mitogen-activated protein kinase 14 | / | 0.440 | |
| 3cly | ACP | Fibroblast growth factor receptor 2 | / | 0.440 | |
| 3kf7 | L9G | Mitogen-activated protein kinase 14 | / | 0.440 | |
| 3ksd | NAD | Glyceraldehyde-3-phosphate dehydrogenase 1 | / | 0.440 | |
| 3nbv | ANP | Ketohexokinase | / | 0.440 | |
| 3oez | STI | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.440 | |
| 3orz | BI4 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.440 | |
| 3vfq | AR6 | Poly [ADP-ribose] polymerase 14 | 2.4.2.30 | 0.440 | |
| 4a8v | 2AN | Major pollen allergen Bet v 1-J | / | 0.440 | |
| 4b4v | L34 | Bifunctional protein FolD | / | 0.440 | |
| 4ft7 | H3K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.440 | |
| 4gj3 | 0XP | Non-receptor tyrosine-protein kinase TYK2 | 2.7.10.2 | 0.440 | |
| 4h1j | 0YH | Protein-tyrosine kinase 2-beta | 2.7.10.2 | 0.440 | |
| 4j54 | G52 | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
| 4pzd | NAD | 3-Hydroxyacyl-CoA dehydrogenase | / | 0.440 | |
| 4xf7 | ACP | Carbohydrate/pyrimidine kinase, PfkB family | / | 0.440 | |
| 5ajq | DB8 | Serine/threonine-protein kinase 10 | 2.7.11.1 | 0.440 |