Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2c6mDT5Cyclin-dependent kinase 22.7.11.22

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
2c6mDT5Cyclin-dependent kinase 22.7.11.221.000
2c6o4SPCyclin-dependent kinase 22.7.11.220.591
3r8uZ31Cyclin-dependent kinase 22.7.11.220.580
1h0w207Cyclin-dependent kinase 22.7.11.220.578
2c6iDT1Cyclin-dependent kinase 22.7.11.220.576
3r71X86Cyclin-dependent kinase 22.7.11.220.575
3r73X87Cyclin-dependent kinase 22.7.11.220.571
2vtpLZ9Cyclin-dependent kinase 22.7.11.220.569
2uzoC62Cyclin-dependent kinase 22.7.11.220.566
2r3r6SCCyclin-dependent kinase 22.7.11.220.562
1w8cN69Cyclin-dependent kinase 22.7.11.220.560
2c69CT8Cyclin-dependent kinase 22.7.11.220.552
2c6kDT2Cyclin-dependent kinase 22.7.11.220.551
2r3gSC9Cyclin-dependent kinase 22.7.11.220.551
2r3iSCFCyclin-dependent kinase 22.7.11.220.551
2btrU73Cyclin-dependent kinase 22.7.11.220.547
2btsU32Cyclin-dependent kinase 22.7.11.220.546
3r8vZ62Cyclin-dependent kinase 22.7.11.220.545
3rm719ZCyclin-dependent kinase 22.7.11.220.544
2c6lDT4Cyclin-dependent kinase 22.7.11.220.540
3iggEFQCyclin-dependent kinase 22.7.11.220.540
3raiX85Cyclin-dependent kinase 22.7.11.220.534
3qxoX65Cyclin-dependent kinase 22.7.11.220.533
4bgh3I6Cyclin-dependent kinase 22.7.11.220.533
3r9hZ67Cyclin-dependent kinase 22.7.11.220.532
3qx2X63Cyclin-dependent kinase 22.7.11.220.531
4fkpLS5Cyclin-dependent kinase 22.7.11.220.530
4fkq42KCyclin-dependent kinase 22.7.11.220.530
1ke7LS3Cyclin-dependent kinase 22.7.11.220.529
3r9nZ68Cyclin-dependent kinase 22.7.11.220.529
2r3o2SCCyclin-dependent kinase 22.7.11.220.525
3sqq99ZCyclin-dependent kinase 22.7.11.220.523
3qtxX43Cyclin-dependent kinase 22.7.11.220.520
2r3p3SCCyclin-dependent kinase 22.7.11.220.518
3qruX19Cyclin-dependent kinase 22.7.11.220.518
4fkg4CKCyclin-dependent kinase 22.7.11.220.518
1ke5LS1Cyclin-dependent kinase 22.7.11.220.516
1pxmCK5Cyclin-dependent kinase 22.7.11.220.515
1oiyN41Cyclin-dependent kinase 22.7.11.220.514
1y8yCT7Cyclin-dependent kinase 22.7.11.220.514
2fvdLIACyclin-dependent kinase 22.7.11.220.514
3qwjX6ACyclin-dependent kinase 22.7.11.220.514
3rni21ZCyclin-dependent kinase 22.7.11.220.513
2vthLZ2Cyclin-dependent kinase 22.7.11.220.512
3qqkX02Cyclin-dependent kinase 22.7.11.220.512
3qqlX03Cyclin-dependent kinase 22.7.11.220.512
3roy22ZCyclin-dependent kinase 22.7.11.220.512
1vyzN5BCyclin-dependent kinase 22.7.11.220.511
2vu3LZECyclin-dependent kinase 22.7.11.220.511
3rpr25ZCyclin-dependent kinase 22.7.11.220.510
1e1xNW1Cyclin-dependent kinase 22.7.11.220.509
4ek610KCyclin-dependent kinase 22.7.11.220.509
1p2a5BNCyclin-dependent kinase 22.7.11.220.508
3pj8404Cyclin-dependent kinase 22.7.11.220.508
3qtuX44Cyclin-dependent kinase 22.7.11.220.507
3r1sX73Cyclin-dependent kinase 22.7.11.220.506
4fkr45KCyclin-dependent kinase 22.7.11.220.506
1h0vUN4Cyclin-dependent kinase 22.7.11.220.505
3rpo24ZCyclin-dependent kinase 22.7.11.220.505
3s00Z60Cyclin-dependent kinase 22.7.11.220.505
3qqfX07Cyclin-dependent kinase 22.7.11.220.504
2c68CT6Cyclin-dependent kinase 22.7.11.220.503
3rpv26ZCyclin-dependent kinase 22.7.11.220.503
3s0o50ZCyclin-dependent kinase 22.7.11.220.503
4ez30S0Cyclin-dependent kinase 22.7.11.220.503
3r7vZ02Cyclin-dependent kinase 22.7.11.220.502
2r64740Cyclin-dependent kinase 22.7.11.220.501
2w06FRVCyclin-dependent kinase 22.7.11.220.500
3qzhX69Cyclin-dependent kinase 22.7.11.220.500
4fkt48KCyclin-dependent kinase 22.7.11.220.499
5aniES4Cyclin-dependent kinase 22.7.11.220.497
2r3fSC8Cyclin-dependent kinase 22.7.11.220.496
3qtzX42Cyclin-dependent kinase 22.7.11.220.495
3ral04ZCyclin-dependent kinase 22.7.11.220.495
1ckpPVBCyclin-dependent kinase 22.7.11.220.493
3r7yZ04Cyclin-dependent kinase 22.7.11.220.492
3r8pZ46Cyclin-dependent kinase 22.7.11.220.492
1oguST8Cyclin-dependent kinase 22.7.11.220.490
3ezrEZRCyclin-dependent kinase 22.7.11.220.490
3r1yX76Cyclin-dependent kinase 22.7.11.220.490
3r8lZ30Cyclin-dependent kinase 22.7.11.220.490
3r9dX6BCyclin-dependent kinase 22.7.11.220.489
4ek816KCyclin-dependent kinase 22.7.11.220.488
2r3lSCWCyclin-dependent kinase 22.7.11.220.486
2vtlLZ5Cyclin-dependent kinase 22.7.11.220.486
3rk909ZCyclin-dependent kinase 22.7.11.220.486
3rm618ZCyclin-dependent kinase 22.7.11.220.486
4eor4SPCyclin-dependent kinase 22.7.11.220.486
3s2pPMUCyclin-dependent kinase 22.7.11.220.485
1w0xOLOCyclin-dependent kinase 22.7.11.220.484
2exmZIPCyclin-dependent kinase 22.7.11.220.484
3r6xX84Cyclin-dependent kinase 22.7.11.220.484
1ke8LS4Cyclin-dependent kinase 22.7.11.220.481
1oi9N20Cyclin-dependent kinase 22.7.11.220.481
2vtsLZCCyclin-dependent kinase 22.7.11.220.481
3qu0X40Cyclin-dependent kinase 22.7.11.220.481
3qzgX67Cyclin-dependent kinase 22.7.11.220.480
3rk708ZCyclin-dependent kinase 22.7.11.220.480
4fkj11KCyclin-dependent kinase 22.7.11.220.480
3r28XA0Cyclin-dependent kinase 22.7.11.220.479
3rk507ZCyclin-dependent kinase 22.7.11.220.479
1ke6LS2Cyclin-dependent kinase 22.7.11.220.478
2vtiLZ3Cyclin-dependent kinase 22.7.11.220.478
4fkw62KCyclin-dependent kinase 22.7.11.220.478
1e1vCMGCyclin-dependent kinase 22.7.11.220.477
2w05FRTCyclin-dependent kinase 22.7.11.220.477
3qrtX14Cyclin-dependent kinase 22.7.11.220.477
3rjc06ZCyclin-dependent kinase 22.7.11.220.477
1unlRRCCyclin-dependent-like kinase 52.7.11.10.475
2b55D31Cyclin-dependent kinase 22.7.11.220.475
3r83Z14Cyclin-dependent kinase 22.7.11.220.475
3rak03ZCyclin-dependent kinase 22.7.11.220.474
3lfqA28Cyclin-dependent kinase 22.7.11.220.473
3qqhX0ACyclin-dependent kinase 22.7.11.220.473
1v1k3FPCyclin-dependent kinase 22.7.11.220.471
2duv371Cyclin-dependent kinase 22.7.11.220.471
2iw84SPCyclin-dependent kinase 22.7.11.220.471
2w1hL0FCyclin-dependent kinase 22.7.11.220.471
3my5RFZCyclin-dependent kinase 22.7.11.220.471
3qtsX46Cyclin-dependent kinase 22.7.11.220.471
4eol1ROCyclin-dependent kinase 22.7.11.220.471
1vyw292Cyclin-dependent kinase 22.7.11.220.470
3qwkX62Cyclin-dependent kinase 22.7.11.220.470
3r7uX96Cyclin-dependent kinase 22.7.11.220.470
1b38ATPCyclin-dependent kinase 22.7.11.220.469
3r1qX75Cyclin-dependent kinase 22.7.11.220.469
1fvv107Cyclin-dependent kinase 22.7.11.220.468
2vttLZDCyclin-dependent kinase 22.7.11.220.468
3ezvEZVCyclin-dependent kinase 22.7.11.220.468
1oirHDYCyclin-dependent kinase 22.7.11.220.467
3ig7EFPCyclin-dependent kinase 22.7.11.220.467
3lfsA07Cyclin-dependent kinase 22.7.11.220.467
1gih1PUCyclin-dependent kinase 22.7.11.220.466
2vtjLZ4Cyclin-dependent kinase 22.7.11.220.466
4fko20KCyclin-dependent kinase 22.7.11.220.466
2c4g514Cyclin-dependent kinase 22.7.11.220.465
2j9mPY8Cyclin-dependent kinase 22.7.11.220.465
2uznC96Cyclin-dependent kinase 22.7.11.220.465
3r7iX9ICyclin-dependent kinase 22.7.11.220.465
3ddpRC8Cyclin-dependent kinase 22.7.11.220.464
3s1h56ZCyclin-dependent kinase 22.7.11.220.464
4lyn1YGCyclin-dependent kinase 22.7.11.220.463
1pxoCK7Cyclin-dependent kinase 22.7.11.220.462
1r78FMDCyclin-dependent kinase 22.7.11.220.462
1ykr628Cyclin-dependent kinase 22.7.11.220.462
1fvt106Cyclin-dependent kinase 22.7.11.220.461
1gz8MBPCyclin-dependent kinase 22.7.11.220.461
2r3q5SCCyclin-dependent kinase 22.7.11.220.461
3qziX72Cyclin-dependent kinase 22.7.11.220.461
1dm2HMDCyclin-dependent kinase 22.7.11.220.460
1h1r6CPCyclin-dependent kinase 22.7.11.220.460
1pxkCK3Cyclin-dependent kinase 22.7.11.220.460
3qxpX64Cyclin-dependent kinase 22.7.11.220.460
3sw418KCyclin-dependent kinase 22.7.11.220.460
4fki09KCyclin-dependent kinase 22.7.11.220.460
1h1s4SPCyclin-dependent kinase 22.7.11.220.459
2a0cCK9Cyclin-dependent kinase 22.7.11.220.459
2b54D05Cyclin-dependent kinase 22.7.11.220.459
1pxlCK4Cyclin-dependent kinase 22.7.11.220.458
1b39ATPCyclin-dependent kinase 22.7.11.220.457
1pxpCK8Cyclin-dependent kinase 22.7.11.220.457
2xmyCDKCyclin-dependent kinase 22.7.11.220.457
4fx360KCyclin-dependent kinase 22.7.11.220.457
2vv9IM9Cyclin-dependent kinase 22.7.11.220.456
2wxvWXVCyclin-dependent kinase 22.7.11.220.456
3rmf20ZCyclin-dependent kinase 22.7.11.220.456
2vtnLZ7Cyclin-dependent kinase 22.7.11.220.455
4fkv61KCyclin-dependent kinase 22.7.11.220.455
1y91CT9Cyclin-dependent kinase 22.7.11.220.453
2wihP48Cyclin-dependent kinase 22.7.11.220.453
1v0pPVBCell division control protein 2 homolog2.7.11.220.452
2b52D42Cyclin-dependent kinase 22.7.11.220.452
3lfnA27Cyclin-dependent kinase 22.7.11.220.452
3qzfX66Cyclin-dependent kinase 22.7.11.220.452
3r7eX88Cyclin-dependent kinase 22.7.11.220.452
4fks46KCyclin-dependent kinase 22.7.11.220.452
2a4lRRCCyclin-dependent kinase 22.7.11.220.451
3fz1B98Cyclin-dependent kinase 22.7.11.220.450
3unj0BXCyclin-dependent kinase 22.7.11.220.450
1ke9LS5Cyclin-dependent kinase 22.7.11.220.449
2b53D23Cyclin-dependent kinase 22.7.11.220.449
2r3kSCQCyclin-dependent kinase 22.7.11.220.449
1oitHDTCyclin-dependent kinase 22.7.11.220.447
2x1nX1NCyclin-dependent kinase 22.7.11.220.447
3rpy27ZCyclin-dependent kinase 22.7.11.220.447
2i40BLZCyclin-dependent kinase 22.7.11.220.446
4bcmT7ZCyclin-dependent kinase 22.7.11.220.446
3sw719KCyclin-dependent kinase 22.7.11.220.445
1g5sI17Cyclin-dependent kinase 22.7.11.220.444
2iw6QQ2Cyclin-dependent kinase 22.7.11.220.444
2iw94SPCyclin-dependent kinase 22.7.11.220.444
3unk0BYCyclin-dependent kinase 22.7.11.220.444
1hckATPCyclin-dependent kinase 22.7.11.220.442
2bhhRYUCyclin-dependent kinase 22.7.11.220.442
2r3mSCXCyclin-dependent kinase 22.7.11.220.442
1gij2PUCyclin-dependent kinase 22.7.11.220.441
3dogNNNCyclin-dependent kinase 22.7.11.220.441
3qtqX35Cyclin-dependent kinase 22.7.11.220.441
3ddqRRCCyclin-dependent kinase 22.7.11.220.440
3ti1B49Cyclin-dependent kinase 22.7.11.220.440
4bcqTJFCyclin-dependent kinase 22.7.11.220.440