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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1e1vCMGCyclin-dependent kinase 22.7.11.22

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
1e1vCMGCyclin-dependent kinase 22.7.11.221.000
3r73X87Cyclin-dependent kinase 22.7.11.220.635
1b39ATPCyclin-dependent kinase 22.7.11.220.614
3qqkX02Cyclin-dependent kinase 22.7.11.220.583
1vyzN5BCyclin-dependent kinase 22.7.11.220.581
3qqfX07Cyclin-dependent kinase 22.7.11.220.581
3r71X86Cyclin-dependent kinase 22.7.11.220.581
1e1xNW1Cyclin-dependent kinase 22.7.11.220.580
2r3gSC9Cyclin-dependent kinase 22.7.11.220.578
3qtuX44Cyclin-dependent kinase 22.7.11.220.568
3iggEFQCyclin-dependent kinase 22.7.11.220.565
5aniES4Cyclin-dependent kinase 22.7.11.220.565
1h0w207Cyclin-dependent kinase 22.7.11.220.563
3qruX19Cyclin-dependent kinase 22.7.11.220.562
3r7yZ04Cyclin-dependent kinase 22.7.11.220.555
1pxkCK3Cyclin-dependent kinase 22.7.11.220.552
2r3o2SCCyclin-dependent kinase 22.7.11.220.550
3rpo24ZCyclin-dependent kinase 22.7.11.220.550
2r3r6SCCyclin-dependent kinase 22.7.11.220.549
3qx4X4BCyclin-dependent kinase 22.7.11.220.547
3ql8X01Cyclin-dependent kinase 22.7.11.220.546
3qzgX67Cyclin-dependent kinase 22.7.11.220.544
3rpr25ZCyclin-dependent kinase 22.7.11.220.544
3rk909ZCyclin-dependent kinase 22.7.11.220.543
3s0o50ZCyclin-dependent kinase 22.7.11.220.543
3qwjX6ACyclin-dependent kinase 22.7.11.220.542
4fkr45KCyclin-dependent kinase 22.7.11.220.542
1b38ATPCyclin-dependent kinase 22.7.11.220.537
1h0vUN4Cyclin-dependent kinase 22.7.11.220.537
2c6mDT5Cyclin-dependent kinase 22.7.11.220.537
3qx2X63Cyclin-dependent kinase 22.7.11.220.535
1w8cN69Cyclin-dependent kinase 22.7.11.220.533
2c69CT8Cyclin-dependent kinase 22.7.11.220.532
4eos1ROCyclin-dependent kinase 22.7.11.220.532
1h1pCMGCyclin-dependent kinase 22.7.11.220.530
3r6xX84Cyclin-dependent kinase 22.7.11.220.530
3rpy27ZCyclin-dependent kinase 22.7.11.220.530
4ek610KCyclin-dependent kinase 22.7.11.220.530
3rahO1ZCyclin-dependent kinase 22.7.11.220.529
3qqhX0ACyclin-dependent kinase 22.7.11.220.528
3rk708ZCyclin-dependent kinase 22.7.11.220.525
4eor4SPCyclin-dependent kinase 22.7.11.220.525
3qziX72Cyclin-dependent kinase 22.7.11.220.524
3raiX85Cyclin-dependent kinase 22.7.11.220.523
3rm719ZCyclin-dependent kinase 22.7.11.220.522
3r1sX73Cyclin-dependent kinase 22.7.11.220.520
3qxoX65Cyclin-dependent kinase 22.7.11.220.519
4fkg4CKCyclin-dependent kinase 22.7.11.220.519
3r83Z14Cyclin-dependent kinase 22.7.11.220.518
3sqq99ZCyclin-dependent kinase 22.7.11.220.518
1h1r6CPCyclin-dependent kinase 22.7.11.220.517
3qqlX03Cyclin-dependent kinase 22.7.11.220.515
4ek816KCyclin-dependent kinase 22.7.11.220.515
3fz1B98Cyclin-dependent kinase 22.7.11.220.512
1oiyN41Cyclin-dependent kinase 22.7.11.220.511
4eol1ROCyclin-dependent kinase 22.7.11.220.511
4ez30S0Cyclin-dependent kinase 22.7.11.220.511
4eon1ROCyclin-dependent kinase 22.7.11.220.510
2r3iSCFCyclin-dependent kinase 22.7.11.220.509
3rpv26ZCyclin-dependent kinase 22.7.11.220.509
1h1q2A6Cyclin-dependent kinase 22.7.11.220.508
1oguST8Cyclin-dependent kinase 22.7.11.220.508
3r9hZ67Cyclin-dependent kinase 22.7.11.220.508
3qu0X40Cyclin-dependent kinase 22.7.11.220.507
3qtzX42Cyclin-dependent kinase 22.7.11.220.506
1gz8MBPCyclin-dependent kinase 22.7.11.220.504
2r64740Cyclin-dependent kinase 22.7.11.220.504
3ig7EFPCyclin-dependent kinase 22.7.11.220.504
3ral04ZCyclin-dependent kinase 22.7.11.220.504
3rmf20ZCyclin-dependent kinase 22.7.11.220.504
3roy22ZCyclin-dependent kinase 22.7.11.220.503
1ke5LS1Cyclin-dependent kinase 22.7.11.220.502
3r7eX88Cyclin-dependent kinase 22.7.11.220.501
3rm618ZCyclin-dependent kinase 22.7.11.220.501
3s00Z60Cyclin-dependent kinase 22.7.11.220.501
4kd11QKCyclin-dependent kinase 22.7.11.220.501
3lfnA27Cyclin-dependent kinase 22.7.11.220.499
4fkq42KCyclin-dependent kinase 22.7.11.220.499
1v1k3FPCyclin-dependent kinase 22.7.11.220.498
3qtxX43Cyclin-dependent kinase 22.7.11.220.498
4eomATPCyclin-dependent kinase 22.7.11.220.497
3qwkX62Cyclin-dependent kinase 22.7.11.220.495
3ti1B49Cyclin-dependent kinase 22.7.11.220.495
1p2a5BNCyclin-dependent kinase 22.7.11.220.494
3r1yX76Cyclin-dependent kinase 22.7.11.220.494
3r8pZ46Cyclin-dependent kinase 22.7.11.220.494
4eop1ROCyclin-dependent kinase 22.7.11.220.494
2vtnLZ7Cyclin-dependent kinase 22.7.11.220.493
3qtrX36Cyclin-dependent kinase 22.7.11.220.493
4fkpLS5Cyclin-dependent kinase 22.7.11.220.493
3lfsA07Cyclin-dependent kinase 22.7.11.220.492
3r7iX9ICyclin-dependent kinase 22.7.11.220.492
4bgh3I6Cyclin-dependent kinase 22.7.11.220.492
4fkj11KCyclin-dependent kinase 22.7.11.220.492
1vyw292Cyclin-dependent kinase 22.7.11.220.491
3ddqRRCCyclin-dependent kinase 22.7.11.220.491
3rk507ZCyclin-dependent kinase 22.7.11.220.491
2btsU32Cyclin-dependent kinase 22.7.11.220.490
3qzhX69Cyclin-dependent kinase 22.7.11.220.490
3r7vZ02Cyclin-dependent kinase 22.7.11.220.489
3r8uZ31Cyclin-dependent kinase 22.7.11.220.489
1pxmCK5Cyclin-dependent kinase 22.7.11.220.488
1ykr628Cyclin-dependent kinase 22.7.11.220.488
1oi9N20Cyclin-dependent kinase 22.7.11.220.487
2btrU73Cyclin-dependent kinase 22.7.11.220.486
4lyn1YGCyclin-dependent kinase 22.7.11.220.486
3ezrEZRCyclin-dependent kinase 22.7.11.220.485
3lfqA28Cyclin-dependent kinase 22.7.11.220.485
3unk0BYCyclin-dependent kinase 22.7.11.220.485
4bcpT3CCyclin-dependent kinase 22.7.11.220.485
1g5sI17Cyclin-dependent kinase 22.7.11.220.483
4i3zADPCyclin-dependent kinase 22.7.11.220.483
1ckpPVBCyclin-dependent kinase 22.7.11.220.482
1ke6LS2Cyclin-dependent kinase 22.7.11.220.482
1r78FMDCyclin-dependent kinase 22.7.11.220.482
2a4lRRCCyclin-dependent kinase 22.7.11.220.482
1gy3ATPCyclin-dependent kinase 22.7.11.220.481
2c6iDT1Cyclin-dependent kinase 22.7.11.220.481
3py0SU9Cyclin-dependent kinase 22.7.11.220.481
2vtjLZ4Cyclin-dependent kinase 22.7.11.220.480
2vtpLZ9Cyclin-dependent kinase 22.7.11.220.480
3r28XA0Cyclin-dependent kinase 22.7.11.220.480
3rak03ZCyclin-dependent kinase 22.7.11.220.479
3s1h56ZCyclin-dependent kinase 22.7.11.220.479
4fki09KCyclin-dependent kinase 22.7.11.220.479
1dm2HMDCyclin-dependent kinase 22.7.11.220.478
2uzoC62Cyclin-dependent kinase 22.7.11.220.478
3rzb02ZCyclin-dependent kinase 22.7.11.220.478
1ke7LS3Cyclin-dependent kinase 22.7.11.220.477
1gih1PUCyclin-dependent kinase 22.7.11.220.476
1ke9LS5Cyclin-dependent kinase 22.7.11.220.476
1w0xOLOCyclin-dependent kinase 22.7.11.220.476
2b55D31Cyclin-dependent kinase 22.7.11.220.476
3qtqX35Cyclin-dependent kinase 22.7.11.220.476
3r7uX96Cyclin-dependent kinase 22.7.11.220.476
3rjc06ZCyclin-dependent kinase 22.7.11.220.476
2b52D42Cyclin-dependent kinase 22.7.11.220.475
1h1s4SPCyclin-dependent kinase 22.7.11.220.474
2r3p3SCCyclin-dependent kinase 22.7.11.220.474
2vtlLZ5Cyclin-dependent kinase 22.7.11.220.473
3r1qX75Cyclin-dependent kinase 22.7.11.220.473
4fx360KCyclin-dependent kinase 22.7.11.220.472
1pxlCK4Cyclin-dependent kinase 22.7.11.220.471
1oitHDTCyclin-dependent kinase 22.7.11.220.470
2vttLZDCyclin-dependent kinase 22.7.11.220.470
3qzfX66Cyclin-dependent kinase 22.7.11.220.470
3r8lZ30Cyclin-dependent kinase 22.7.11.220.468
1oiuN76Cyclin-dependent kinase 22.7.11.220.467
3bhtMFRCyclin-dependent kinase 22.7.11.220.466
4fkw62KCyclin-dependent kinase 22.7.11.220.466
2xmyCDKCyclin-dependent kinase 22.7.11.220.465
3qtwX3ACyclin-dependent kinase 22.7.11.220.464
1gij2PUCyclin-dependent kinase 22.7.11.220.463
3ddpRC8Cyclin-dependent kinase 22.7.11.220.463
3tiz3TICyclin-dependent kinase 22.7.11.220.462
4fkt48KCyclin-dependent kinase 22.7.11.220.462
1pxoCK7Cyclin-dependent kinase 22.7.11.220.461
1unlRRCCyclin-dependent-like kinase 52.7.11.10.461
3sw418KCyclin-dependent kinase 22.7.11.220.461
4fko20KCyclin-dependent kinase 22.7.11.220.461
1ke8LS4Cyclin-dependent kinase 22.7.11.220.460
1urwI1PCyclin-dependent kinase 22.7.11.220.460
4acm7YGCyclin-dependent kinase 22.7.11.220.460
4fklCK2Cyclin-dependent kinase 22.7.11.220.459
3rni21ZCyclin-dependent kinase 22.7.11.220.458
1jstATPCyclin-dependent kinase 22.7.11.220.457
3s2pPMUCyclin-dependent kinase 22.7.11.220.457
2iw94SPCyclin-dependent kinase 22.7.11.220.455
2w06FRVCyclin-dependent kinase 22.7.11.220.455
3r9oZ71Cyclin-dependent kinase 22.7.11.220.455
3wblPDYCyclin-dependent kinase 22.7.11.220.455
1qmzATPCyclin-dependent kinase 22.7.11.220.453
2b54D05Cyclin-dependent kinase 22.7.11.220.453
2bhhRYUCyclin-dependent kinase 22.7.11.220.453
2wpa889Cyclin-dependent kinase 22.7.11.220.453
3rkb12ZCyclin-dependent kinase 22.7.11.220.453
4eoi1ROCyclin-dependent kinase 22.7.11.220.453
2iw84SPCyclin-dependent kinase 22.7.11.220.452
3unj0BXCyclin-dependent kinase 22.7.11.220.452
1di8DTQCyclin-dependent kinase 22.7.11.220.451
2r3kSCQCyclin-dependent kinase 22.7.11.220.451
2vtiLZ3Cyclin-dependent kinase 22.7.11.220.451
4nj32KDCyclin-dependent kinase 22.7.11.220.451
2c68CT6Cyclin-dependent kinase 22.7.11.220.449
3dogNNNCyclin-dependent kinase 22.7.11.220.449
3pj8404Cyclin-dependent kinase 22.7.11.220.449
4eok4SPCyclin-dependent kinase 22.7.11.220.449
4fv8E63Mitogen-activated protein kinase 12.7.11.240.449
3r9dX6BCyclin-dependent kinase 22.7.11.220.448
3uli1N3Cyclin-dependent kinase 22.7.11.220.448
2c4g514Cyclin-dependent kinase 22.7.11.220.447
2w1hL0FCyclin-dependent kinase 22.7.11.220.447
4cfnJYMCyclin-dependent kinase 22.7.11.220.446
1oiqHDUCyclin-dependent kinase 22.7.11.220.445
2r3lSCWCyclin-dependent kinase 22.7.11.220.445
2vtsLZCCyclin-dependent kinase 22.7.11.220.444
4au8Z3RCyclin-dependent-like kinase 52.7.11.10.444
1e9hINRCyclin-dependent kinase 22.7.11.220.443
2uzlC94Cyclin-dependent kinase 22.7.11.220.443
4bcnT9NCyclin-dependent kinase 22.7.11.220.443
4fks46KCyclin-dependent kinase 22.7.11.220.443
3tkiS25Serine/threonine-protein kinase Chk12.7.11.10.441
2cchATPCyclin-dependent kinase 22.7.11.220.440
3tnwF18Cyclin-dependent kinase 22.7.11.220.440