sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3ibq | ATP | Pyridoxal kinase |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 3ibq | ATP | Pyridoxal kinase | / | 1.000 | |
| 1rfv | ADP | Pyridoxal kinase | 2.7.1.35 | 0.572 | |
| 3hyo | ADP | Pyridoxal kinase | / | 0.540 | |
| 1rfu | ADP | Pyridoxal kinase | 2.7.1.35 | 0.526 | |
| 2ddo | ATP | Pyridoxine/pyridoxal/pyridoxamine kinase | / | 0.509 | |
| 3keu | ATP | Pyridoxal kinase | 2.7.1.35 | 0.500 | |
| 3fhy | ATP | Pyridoxal kinase | 2.7.1.35 | 0.496 | |
| 3hx4 | ANP | Calmodulin-domain protein kinase 1 | / | 0.493 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.491 | |
| 3u9e | COA | Lmo1369 protein | / | 0.489 | |
| 3s1d | ZIR | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.488 | |
| 2ejv | NAD | L-threonine 3-dehydrogenase | / | 0.487 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.486 | |
| 1nzd | UPG | DNA beta-glucosyltransferase | / | 0.485 | |
| 2chz | 093 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.483 | |
| 3nd1 | SAH | Precorrin-6A synthase (Deacetylating) | / | 0.482 | |
| 2xck | MH4 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.481 | |
| 1zrz | BI1 | Protein kinase C iota type | 2.7.11.13 | 0.480 | |
| 2yxu | ATP | Pyridoxal kinase | 2.7.1.35 | 0.479 | |
| 4en4 | ATP | Pyridoxal kinase | 2.7.1.35 | 0.479 | |
| 1bxk | NAD | dTDP-glucose 4,6-dehydratase 2 | / | 0.476 | |
| 4bkz | 1WS | Maternal embryonic leucine zipper kinase | 2.7.11.1 | 0.476 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.476 | |
| 5ar4 | SB2 | Receptor-interacting serine/threonine-protein kinase 2 | 2.7.11.1 | 0.476 | |
| 2qo9 | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.475 | |
| 4fv3 | EK6 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.474 | |
| 2bro | DF2 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.473 | |
| 2clq | STU | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.473 | |
| 1bsv | NDP | GDP-L-fucose synthase | / | 0.471 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.471 | |
| 2oap | ANP | Type II secretion system protein (GspE-2) | / | 0.471 | |
| 1teh | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.470 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.470 | |
| 2vwx | 7X4 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.470 | |
| 3flk | NAI | Tartrate dehydrogenase/decarboxylase | 1.1.1.93 | 0.470 | |
| 1hdc | CBO | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.469 | |
| 4gk3 | L87 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.469 | |
| 5a4k | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.469 | |
| 1u8v | FAD | 4-hydroxybutyryl-CoA dehydratase/vinylacetyl-CoA-Delta-isomerase | / | 0.468 | |
| 3ixp | 834 | Ecdysone receptor | / | 0.468 | |
| 1f17 | NAI | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.467 | |
| 2qen | ADP | Walker-Type ATPase | / | 0.467 | |
| 3i5z | Z48 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.466 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.466 | |
| 4ocp | ADP | N-acetylhexosamine 1-kinase | 2.7.1.162 | 0.466 | |
| 1bvr | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.465 | |
| 1kkq | 471 | Peroxisome proliferator-activated receptor alpha | / | 0.465 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.465 | |
| 3pe2 | E1B | Casein kinase II subunit alpha | 2.7.11.1 | 0.465 | |
| 4g2f | C07 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.465 | |
| 4gk2 | L66 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.465 | |
| 4xf7 | ACP | Carbohydrate/pyrimidine kinase, PfkB family | / | 0.465 | |
| 2z1m | NDP | GDP-mannose 4,6-dehydratase | / | 0.464 | |
| 4tuv | CPZ | Cytochrome P450 119 | 1.14 | 0.464 | |
| 1qbg | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.463 | |
| 2brg | DFY | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.463 | |
| 2p5u | NAD | UDP-glucose 4-epimerase | / | 0.463 | |
| 4m83 | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.463 | |
| 1nup | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.462 | |
| 1nvs | UCM | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.462 | |
| 4dqu | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.462 | |
| 1d4a | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.461 | |
| 1h66 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.461 | |
| 1xe5 | 5FE | Plasmepsin-2 | 3.4.23.39 | 0.461 | |
| 3hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.461 | |
| 3tne | RIT | Candidapepsin-1 | 3.4.23.24 | 0.461 | |
| 4c3f | 7KW | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.461 | |
| 1e3e | NAI | Alcohol dehydrogenase 4 | 1.1.1.1 | 0.460 | |
| 1h51 | FMN | Pentaerythritol tetranitrate reductase | / | 0.460 | |
| 1zmc | NAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.460 | |
| 2dfv | NAD | L-threonine 3-dehydrogenase | / | 0.460 | |
| 3nbv | ANP | Ketohexokinase | / | 0.460 | |
| 4q72 | FAD | Bifunctional protein PutA | / | 0.460 | |
| 2cy0 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.459 | |
| 4f4d | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.459 | |
| 1g1a | NAD | dTDP-glucose 4,6-dehydratase | / | 0.458 | |
| 4m9a | FDA | Acyl-CoA dehydrogenase | / | 0.458 | |
| 4rrv | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.458 | |
| 1dxq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.457 | |
| 2ktd | PUC | Prostaglandin-H2 D-isomerase | 5.3.99.2 | 0.457 | |
| 2wxv | WXV | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.457 | |
| 3qai | XNN | Ketohexokinase | / | 0.457 | |
| 1zem | NAD | Xylitol dehydrogenase | / | 0.456 | |
| 2xyu | Q9G | Ephrin type-A receptor 4 | 2.7.10.1 | 0.456 | |
| 4e5y | NDP | GDP-L-fucose synthase | 1.1.1.271 | 0.456 | |
| 4kzo | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.456 | |
| 3bbr | BHY | Glutamate receptor 2 | / | 0.455 | |
| 3inx | JZC | Heat shock protein HSP 90-alpha | / | 0.455 | |
| 4b7s | QLE | Cytochrome P450 monooxygenase PikC | / | 0.455 | |
| 1h50 | FMN | Pentaerythritol tetranitrate reductase | / | 0.454 | |
| 1jmh | UMP | Thymidylate synthase | / | 0.454 | |
| 1nvt | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.454 | |
| 1xdp | ATP | Polyphosphate kinase | / | 0.454 | |
| 1zth | ADP | RIO-type serine/threonine-protein kinase Rio1 | 2.7.11.1 | 0.454 | |
| 3d8v | UD1 | Bifunctional protein GlmU | / | 0.454 | |
| 3i81 | EBI | Insulin-like growth factor 1 receptor | 2.7.10.1 | 0.454 | |
| 3pqb | VGP | Putative oxidoreductase | / | 0.454 | |
| 3umo | ATP | ATP-dependent 6-phosphofructokinase isozyme 2 | 2.7.1.11 | 0.454 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.454 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.454 | |
| 4gj3 | 0XP | Non-receptor tyrosine-protein kinase TYK2 | 2.7.10.2 | 0.454 | |
| 4xuh | SFI | Peroxisome proliferator-activated receptor gamma | / | 0.454 | |
| 5eai | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.454 | |
| 1y0s | 331 | Peroxisome proliferator-activated receptor delta | / | 0.453 | |
| 2vwz | 7X6 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.453 | |
| 3etd | NDP | Glutamate dehydrogenase 1, mitochondrial | 1.4.1.3 | 0.453 | |
| 3p8i | FMN | Pentaerythritol tetranitrate reductase | / | 0.453 | |
| 4anx | 534 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.453 | |
| 4fsr | HKC | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.453 | |
| 4hgl | 0YO | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.453 | |
| 4v12 | POG | MaoC like domain protein | / | 0.453 | |
| 1sxj | AGS | Replication factor C subunit 1 | / | 0.452 | |
| 2chx | 090 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.452 | |
| 2hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.452 | |
| 2izr | BRK | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.452 | |
| 2vwq | NAP | Glucose 1-dehydrogenase | / | 0.452 | |
| 3gbu | ATP | Uncharacterized sugar kinase PH1459 | 2.7.1 | 0.452 | |
| 3wmx | NAD | NAD dependent epimerase/dehydratase | / | 0.452 | |
| 3zs7 | ATP | Pyridoxine/pyridoxal/pyridoxamine kinase | / | 0.452 | |
| 3zuy | TCH | Transporter | / | 0.452 | |
| 4o0r | X4Z | Serine/threonine-protein kinase PAK 1 | 2.7.11.1 | 0.452 | |
| 4qmx | H8H | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.452 | |
| 4wbo | ANW | Rhodopsin kinase | / | 0.452 | |
| 4xiw | AZM | Carbonic anhydrase, alpha type | / | 0.452 | |
| 4xum | IMN | Peroxisome proliferator-activated receptor gamma | / | 0.452 | |
| 4yr9 | NAD | L-threonine 3-dehydrogenase, mitochondrial | 1.1.1.103 | 0.452 | |
| 1dxo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.451 | |
| 2g22 | 6IG | Renin | 3.4.23.15 | 0.451 | |
| 2rkv | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.451 | |
| 2xfs | J01 | Uncharacterized protein | / | 0.451 | |
| 2xj2 | 985 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.451 | |
| 3hzt | J60 | Calmodulin-like domain protein kinase isoform 3 | / | 0.451 | |
| 3say | OFT | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.451 | |
| 4bzo | 676 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.451 | |
| 4g09 | 0VD | Histidinol dehydrogenase | / | 0.451 | |
| 4yao | FMN | NADPH--cytochrome P450 reductase | / | 0.451 | |
| 2b7a | IZA | Tyrosine-protein kinase JAK2 | / | 0.450 | |
| 2d29 | FAD | Acyl-CoA dehydrogenase | / | 0.450 | |
| 3a1n | NAD | NDP-sugar epimerase | / | 0.450 | |
| 3c1y | 2BA | DNA integrity scanning protein DisA | / | 0.450 | |
| 3gw9 | VNI | Lanosterol 14-alpha-demethylase | / | 0.450 | |
| 4a6n | FAD | TetX family tetracycline inactivation enzyme | / | 0.450 | |
| 4a99 | FAD | TetX family tetracycline inactivation enzyme | / | 0.450 | |
| 4bge | PYW | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.450 | |
| 5hs1 | VOR | Lanosterol 14-alpha demethylase | / | 0.450 | |
| 1byg | STU | Tyrosine-protein kinase CSK | / | 0.449 | |
| 1g2v | TTP | Glucose-1-phosphate thymidylyltransferase | / | 0.449 | |
| 2c59 | NAD | GDP-mannose 3,5-epimerase | 5.1.3.18 | 0.449 | |
| 3b9l | AZZ | Serum albumin | / | 0.449 | |
| 3g49 | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.449 | |
| 3had | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.449 | |
| 3sf6 | FDA | Glutaryl-CoA dehydrogenase | / | 0.449 | |
| 4asu | ADP | ATP synthase subunit alpha, mitochondrial | / | 0.449 | |
| 4bf2 | STU | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.449 | |
| 4ge7 | 0K5 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.449 | |
| 4ly9 | 1YY | Glucokinase regulatory protein | / | 0.449 | |
| 5ack | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.449 | |
| 1gqt | ACP | Ribokinase | / | 0.448 | |
| 1j39 | UPG | DNA beta-glucosyltransferase | / | 0.448 | |
| 2brn | DF1 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.448 | |
| 2cgw | 3C3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.448 | |
| 2hk9 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.448 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.448 | |
| 3f03 | FMN | Pentaerythritol tetranitrate reductase | / | 0.448 | |
| 3mpj | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.448 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.448 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.448 | |
| 4lj9 | ACP | Chaperone protein ClpB | / | 0.448 | |
| 1h69 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.447 | |
| 1kp3 | ATP | Argininosuccinate synthase | 6.3.4.5 | 0.447 | |
| 2hun | NAD | 336aa long hypothetical dTDP-glucose 4,6-dehydratase | / | 0.447 | |
| 2xgo | ZKD | Uncharacterized protein | / | 0.447 | |
| 2xvd | AS6 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.447 | |
| 3bht | MFR | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.447 | |
| 3etg | NDP | Glutamate dehydrogenase 1, mitochondrial | 1.4.1.3 | 0.447 | |
| 3o03 | NAP | Dehydrogenase with different specificities (Related to short-chain alcohol dehydrogenase) | / | 0.447 | |
| 4c34 | STU | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.447 | |
| 4qmz | B49 | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.447 | |
| 1gg5 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.446 | |
| 2g5c | NAD | Prephenate dehydrogenase | / | 0.446 | |
| 2i4q | UA4 | Renin | 3.4.23.15 | 0.446 | |
| 2lba | CHO | Fatty acid binding protein 6 | / | 0.446 | |
| 2rh9 | IGP | Tryptophan synthase alpha chain | / | 0.446 | |
| 3p82 | FMN | Pentaerythritol tetranitrate reductase | / | 0.446 | |
| 3slk | NDP | Polyketide synthase extender module 2 | / | 0.446 | |
| 4ewn | 0VR | Imidazole glycerol phosphate synthase subunit HisF | 4.1.3 | 0.446 | |
| 4u0m | GTP | Cyclic GMP-AMP synthase | / | 0.446 | |
| 5dqr | FAD | 7-hydroxymethyl chlorophyll a reductase, chloroplastic | 1.17.7.2 | 0.446 | |
| 1fxs | NAP | GDP-L-fucose synthase | / | 0.445 | |
| 1noo | CAH | Camphor 5-monooxygenase | 1.14.15.1 | 0.445 | |
| 1nvq | UCN | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.445 | |
| 2fy4 | COA | Choline O-acetyltransferase | 2.3.1.6 | 0.445 | |
| 2nry | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.445 | |
| 2yn8 | STU | Ephrin type-B receptor 4 | 2.7.10.1 | 0.445 | |
| 3elj | GS7 | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.445 | |
| 3tjz | GNP | ADP-ribosylation factor 1 | / | 0.445 | |
| 4bzn | UGX | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.445 | |
| 4e4m | 0NH | Tyrosine-protein kinase JAK2 | / | 0.445 | |
| 4kky | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.445 | |
| 4v2g | ITC | Tetracycline repressor protein class D | / | 0.445 | |
| 4wec | NAD | Short chain dehydrogenase | / | 0.445 | |
| 4y9q | C2E | Uncharacterized protein | / | 0.445 | |
| 1kbo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.444 | |
| 1kh3 | ANP | Argininosuccinate synthase | / | 0.444 | |
| 1kp2 | ATP | Argininosuccinate synthase | 6.3.4.5 | 0.444 | |
| 1n2h | PAJ | Pantothenate synthetase | 6.3.2.1 | 0.444 | |
| 1o9b | NAI | Quinate/shikimate dehydrogenase | / | 0.444 | |
| 1yw2 | PGJ | Mitogen-activated protein kinase 14 | / | 0.444 | |
| 2fr0 | NDP | 6-deoxyerythronolide-B synthase EryA1, modules 1 and 2 | / | 0.444 | |
| 2iyf | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.444 | |
| 2jcx | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | / | 0.444 | |
| 2ojg | 19A | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.444 | |
| 2vn0 | TDZ | Cytochrome P450 2C8 | / | 0.444 | |
| 3apf | BMW | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.444 | |
| 3lsh | FAD | Pyranose 2-oxidase | / | 0.444 | |
| 3tri | NAP | Pyrroline-5-carboxylate reductase | / | 0.444 | |
| 4bb4 | 32W | Ephrin type-B receptor 4 | 2.7.10.1 | 0.444 | |
| 4fhk | 0U0 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.444 | |
| 5a3b | APR | SIR2 family protein | / | 0.444 | |
| 1cul | FOK | Adenylate cyclase type 2 | / | 0.443 | |
| 1cul | FOK | Adenylate cyclase type 5 | / | 0.443 | |
| 1eio | GCH | Gastrotropin | / | 0.443 | |
| 1ej2 | NAD | Nicotinamide-nucleotide adenylyltransferase | 2.7.7.1 | 0.443 | |
| 1mp0 | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.443 | |
| 2uzl | C94 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.443 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
| 2vx1 | 7X8 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.443 | |
| 3cbl | STU | Tyrosine-protein kinase Fes/Fps | 2.7.10.2 | 0.443 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.443 | |
| 3oqk | S52 | Renin | 3.4.23.15 | 0.443 | |
| 3q92 | XNB | Ketohexokinase | / | 0.443 | |
| 3spt | UD1 | Bifunctional protein GlmU | / | 0.443 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.443 | |
| 4i6a | HMG | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 1.1.1.88 | 0.443 | |
| 4ipw | 1G7 | Mycocyclosin synthase | 1.14.21.9 | 0.443 | |
| 4jnk | ZHK | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.443 | |
| 4yxm | 2BA | DNA integrity scanning protein DisA | / | 0.443 | |
| 1cf3 | FAD | Glucose oxidase | 1.1.3.4 | 0.442 | |
| 1eh4 | IC1 | Casein kinase I homolog 1 | 2.7.11.1 | 0.442 | |
| 1fm4 | DXC | Major pollen allergen Bet v 1-L | / | 0.442 | |
| 1kc1 | NDP | dTDP-4-dehydrorhamnose reductase | 1.1.1.133 | 0.442 | |
| 1kfb | IGP | Tryptophan synthase alpha chain | / | 0.442 | |
| 2ev9 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.442 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
| 2vna | NAP | Prostaglandin reductase 2 | 1.3.1.48 | 0.442 | |
| 2xx9 | 1NF | Glutamate receptor 2 | / | 0.442 | |
| 3a4v | NAD | NDP-sugar epimerase | / | 0.442 | |
| 3ajr | NAD | NDP-sugar epimerase | / | 0.442 | |
| 3cxw | 7CP | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.442 | |
| 3r83 | Z14 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.442 | |
| 3umv | FAD | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.442 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
| 4a6c | QG9 | Gag-Pol polyprotein | 3.4.23.16 | 0.442 | |
| 4anv | 751 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.442 | |
| 4eyw | L0R | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.442 | |
| 4gb9 | 0WR | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.442 | |
| 4gk4 | L90 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.442 | |
| 4uym | VOR | 14-alpha sterol demethylase Cyp51B | / | 0.442 | |
| 1e7q | NAP | GDP-L-fucose synthase | / | 0.441 | |
| 1e90 | MYC | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.441 | |
| 1nhh | ANP | DNA mismatch repair protein MutL | / | 0.441 | |
| 1ywg | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.441 | |
| 2he5 | NDP | Aldo-keto reductase family 1 member C21 | 1.1.1 | 0.441 | |
| 2izu | P01 | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.441 | |
| 2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.441 | |
| 2q5g | 1FA | Peroxisome proliferator-activated receptor delta | / | 0.441 | |
| 2wih | P48 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.441 | |
| 3atz | FMN | Prostaglandin F2a synthase | / | 0.441 | |
| 3doc | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.441 | |
| 3em0 | CHD | Fatty acid-binding protein 6, ileal (gastrotropin) | / | 0.441 | |
| 3il1 | B5D | Glutamate receptor 2 | / | 0.441 | |
| 4e2d | FMN | Dehydrogenase | / | 0.441 | |
| 4ft7 | H3K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.441 | |
| 4qmp | DKI | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.441 | |
| 1e8x | ATP | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.440 | |
| 1mkd | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.440 | |
| 1yi3 | LY2 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.440 | |
| 2dft | ADP | Shikimate kinase | 2.7.1.71 | 0.440 | |
| 2ejz | SAH | Diphthine synthase | / | 0.440 | |
| 2ft9 | CHD | Fatty acid-binding protein 2, liver | / | 0.440 | |
| 2hrc | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.440 | |
| 2qd3 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.440 | |
| 2rbe | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.440 | |
| 2vig | FAD | Short-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.1 | 0.440 | |
| 2ww4 | ADP | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | 2.7.1.148 | 0.440 | |
| 2xik | J60 | Serine/threonine-protein kinase 25 | 2.7.11.1 | 0.440 | |
| 3gwf | FAD | Cyclohexanone monooxygenase | / | 0.440 | |
| 3r04 | UNQ | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.440 | |
| 3x2e | NAI | Adenosylhomocysteinase | / | 0.440 | |
| 4cuk | NAI | D-lactate dehydrogenase | / | 0.440 | |
| 4egb | NAD | dTDP-glucose 4,6-dehydratase | / | 0.440 | |
| 4eud | COA | Succinyl-CoA:acetate CoA-transferase | / | 0.440 | |
| 4gdy | 0X1 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.440 | |
| 4nbw | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.440 | |
| 4q73 | FAD | Bifunctional protein PutA | / | 0.440 |