sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3i7g | 732 | Collagenase 3 | 3.4.24 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 3i7g | 732 | Collagenase 3 | 3.4.24 | 1.000 | |
| 2ow1 | 7MR | Matrix metalloproteinase-9 | 3.4.24.35 | 0.626 | |
| 3ljg | EEF | Macrophage metalloelastase | 3.4.24.65 | 0.619 | |
| 1hy7 | MBS | Stromelysin-1 | 3.4.24.17 | 0.615 | |
| 2wo8 | 077 | Macrophage metalloelastase | 3.4.24.65 | 0.614 | |
| 2hu6 | 37A | Macrophage metalloelastase | 3.4.24.65 | 0.613 | |
| 3kry | 3KR | Collagenase 3 | 3.4.24 | 0.609 | |
| 4gr8 | R4C | Macrophage metalloelastase | 3.4.24.65 | 0.604 | |
| 2ow0 | 6MR | Matrix metalloproteinase-9 | 3.4.24.35 | 0.599 | |
| 3ts4 | EEG | Macrophage metalloelastase | 3.4.24.65 | 0.596 | |
| 1utt | CP8 | Macrophage metalloelastase | 3.4.24.65 | 0.595 | |
| 3kej | 3EJ | Collagenase 3 | 3.4.24 | 0.589 | |
| 3lik | EEG | Macrophage metalloelastase | 3.4.24.65 | 0.589 | |
| 2wo9 | 068 | Macrophage metalloelastase | 3.4.24.65 | 0.588 | |
| 4guy | KLJ | Macrophage metalloelastase | 3.4.24.65 | 0.588 | |
| 3lil | EEA | Macrophage metalloelastase | 3.4.24.65 | 0.586 | |
| 4gql | R47 | Macrophage metalloelastase | 3.4.24.65 | 0.586 | |
| 3tsk | QEG | Macrophage metalloelastase | 3.4.24.65 | 0.579 | |
| 2ovx | 4MR | Matrix metalloproteinase-9 | 3.4.24.35 | 0.578 | |
| 2woa | 576 | Macrophage metalloelastase | 3.4.24.65 | 0.577 | |
| 4i03 | L88 | Macrophage metalloelastase | 3.4.24.65 | 0.577 | |
| 3kec | 3KE | Collagenase 3 | 3.4.24 | 0.576 | |
| 4gr3 | R45 | Macrophage metalloelastase | 3.4.24.65 | 0.576 | |
| 1zvx | FIN | Neutrophil collagenase | 3.4.24.34 | 0.575 | |
| 1you | PFD | Collagenase 3 | 3.4.24 | 0.573 | |
| 2d1n | FA4 | Collagenase 3 | 3.4.24 | 0.572 | |
| 1xuc | PB3 | Collagenase 3 | 3.4.24 | 0.571 | |
| 2ovz | 5MR | Matrix metalloproteinase-9 | 3.4.24.35 | 0.570 | |
| 4a7b | 3W5 | Collagenase 3 | 3.4.24 | 0.570 | |
| 1ztq | 033 | Collagenase 3 | 3.4.24 | 0.566 | |
| 4a7b | 3W4 | Collagenase 3 | 3.4.24 | 0.563 | |
| 3o2x | 3O2 | Collagenase 3 | 3.4.24 | 0.560 | |
| 1g49 | 111 | Stromelysin-1 | 3.4.24.17 | 0.546 | |
| 1caq | DPS | Stromelysin-1 | 3.4.24.17 | 0.540 | |
| 4h76 | 10B | Macrophage metalloelastase | 3.4.24.65 | 0.536 | |
| 3i7i | 518 | Collagenase 3 | 3.4.24 | 0.534 | |
| 2yig | 5EL | Collagenase 3 | 3.4.24 | 0.533 | |
| 4g9l | NGH | Stromelysin-1 | 3.4.24.17 | 0.533 | |
| 1c8t | TR1 | Stromelysin-1 | 3.4.24.17 | 0.530 | |
| 1ciz | DPS | Stromelysin-1 | 3.4.24.17 | 0.528 | |
| 1g05 | BBH | Stromelysin-1 | 3.4.24.17 | 0.527 | |
| 1zs0 | EIN | Neutrophil collagenase | 3.4.24.34 | 0.527 | |
| 2d1o | FA4 | Stromelysin-1 | 3.4.24.17 | 0.524 | |
| 4gr0 | R4B | Macrophage metalloelastase | 3.4.24.65 | 0.524 | |
| 1sln | INH | Stromelysin-1 | 3.4.24.17 | 0.521 | |
| 1b8y | IN7 | Stromelysin-1 | 3.4.24.17 | 0.520 | |
| 1hov | I52 | 72 kDa type IV collagenase | 3.4.24.24 | 0.514 | |
| 1d8f | SPI | Stromelysin-1 | 3.4.24.17 | 0.511 | |
| 1hv5 | RXP | Stromelysin-3 | 3.4.24 | 0.509 | |
| 1xur | PB5 | Collagenase 3 | 3.4.24 | 0.507 | |
| 4ja1 | NGH | Stromelysin-1 | 3.4.24.17 | 0.500 | |
| 4dpe | NGH | Stromelysin-1 | 3.4.24.17 | 0.498 | |
| 1g4k | HQQ | Stromelysin-1 | 3.4.24.17 | 0.492 | |
| 4b8w | NAP | GDP-L-fucose synthase | 1.1.1.271 | 0.491 | |
| 3zbr | NAP | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.490 | |
| 2ow2 | 8MR | Matrix metalloproteinase-9 | 3.4.24.35 | 0.488 | |
| 1d8m | BBH | Stromelysin-1 | 3.4.24.17 | 0.487 | |
| 2oxw | ILE_ALA_GLY | Macrophage metalloelastase | 3.4.24.65 | 0.485 | |
| 4fco | 0U4 | Beta-secretase 1 | 3.4.23.46 | 0.483 | |
| 5dbf | NDP | Iridoid synthase | 1.3.1.99 | 0.482 | |
| 3cuk | FAD | D-amino-acid oxidase | 1.4.3.3 | 0.481 | |
| 1bzs | BSI | Neutrophil collagenase | 3.4.24.34 | 0.480 | |
| 2wyv | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.480 | |
| 1xkq | NDP | Uncharacterized protein | / | 0.478 | |
| 4lxa | 1YS | Beta-secretase 1 | 3.4.23.46 | 0.478 | |
| 1bqo | N25 | Stromelysin-1 | 3.4.24.17 | 0.477 | |
| 4z64 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.476 | |
| 2pob | GW4 | Peroxisome proliferator-activated receptor gamma | / | 0.475 | |
| 2q1w | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.475 | |
| 3oqf | S51 | Renin | 3.4.23.15 | 0.473 | |
| 3zxh | E41 | Collagenase 3 | 3.4.24 | 0.473 | |
| 4d89 | BXD | Beta-secretase 1 | 3.4.23.46 | 0.473 | |
| 3b6z | CO7 | Enoyl reductase LovC | 1 | 0.472 | |
| 4h3i | 10V | Beta-secretase 1 | 3.4.23.46 | 0.472 | |
| 1yqx | NAP | Sinapyl alcohol dehydrogenase | / | 0.471 | |
| 2y6d | TQJ | Matrilysin | 3.4.24.23 | 0.471 | |
| 2zat | NAP | Dehydrogenase/reductase SDR family member 4 | 1.1.1.184 | 0.470 | |
| 3vg1 | 0GT | Beta-secretase 1 | 3.4.23.46 | 0.470 | |
| 4dh6 | 0KN | Beta-secretase 1 | 3.4.23.46 | 0.470 | |
| 2w0d | CGS | Macrophage metalloelastase | 3.4.24.65 | 0.469 | |
| 5hsa | FAS | Alcohol oxidase 1 | 1.1.3.13 | 0.469 | |
| 2ewm | NAD | (S)-1-Phenylethanol dehydrogenase | 1.1.1.311 | 0.468 | |
| 3bg7 | FAD | Pyranose 2-oxidase | / | 0.468 | |
| 3qof | GDP | Atlastin-1 | 3.6.5 | 0.468 | |
| 4b79 | NAD | Probable short-chain dehydrogenase | / | 0.468 | |
| 4dpf | 0LG | Beta-secretase 1 | 3.4.23.46 | 0.468 | |
| 2woa | 023 | Macrophage metalloelastase | 3.4.24.65 | 0.466 | |
| 4dlb | NAD | S-(hydroxymethyl)glutathione dehydrogenase | / | 0.466 | |
| 2fzw | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.465 | |
| 3tox | NAP | Putative oxidoreductase | / | 0.465 | |
| 4ubv | COA | Steroid 3-ketoacyl-CoA thiolase | / | 0.465 | |
| 1n5d | NDP | Carbonyl reductase [NADPH] 1 | / | 0.464 | |
| 1soz | VAL_TYR_GLN_PHE | Serine endoprotease DegS | 3.4.21.107 | 0.464 | |
| 2y0m | ACO | Histone acetyltransferase KAT8 | / | 0.464 | |
| 3vyf | VYF | Renin | 3.4.23.15 | 0.464 | |
| 5emh | NAP | Iridoid synthase | 1.3.1.99 | 0.464 | |
| 1d7x | SPC | Stromelysin-1 | 3.4.24.17 | 0.463 | |
| 2xls | FAD | Putative flavin-containing monooxygenase | / | 0.463 | |
| 3g49 | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.463 | |
| 3lpj | Z75 | Beta-secretase 1 | 3.4.23.46 | 0.462 | |
| 4ewo | 996 | Beta-secretase 1 | 3.4.23.46 | 0.462 | |
| 1yqd | NAP | Sinapyl alcohol dehydrogenase | / | 0.461 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.461 | |
| 4dpi | 0N1 | Beta-secretase 1 | 3.4.23.46 | 0.461 | |
| 4qec | NAP | ElxO | / | 0.461 | |
| 4yag | NAI | C alpha-dehydrogenase | / | 0.461 | |
| 1xse | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.460 | |
| 2get | COK | Pantothenate kinase | 2.7.1.33 | 0.460 | |
| 2gmh | FAD | Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial | 1.5.5.1 | 0.460 | |
| 3vuc | HHE | Renin | 3.4.23.15 | 0.460 | |
| 4frk | DWD | Beta-secretase 1 | 3.4.23.46 | 0.460 | |
| 3dv5 | BAV | Beta-secretase 1 | 3.4.23.46 | 0.459 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.459 | |
| 4ozt | P1A | Ecdysone receptor, putative | / | 0.459 | |
| 1xe5 | 5FE | Plasmepsin-2 | 3.4.23.39 | 0.458 | |
| 1yb5 | NAP | Quinone oxidoreductase | 1.6.5.5 | 0.458 | |
| 2q2q | NAD | Beta-D-hydroxybutyrate dehydrogenase | / | 0.458 | |
| 2z3l | PHE_ARG_TYR_LEU_GLY | Leucyl/phenylalanyl-tRNA--protein transferase | 2.3.2.6 | 0.458 | |
| 2ztm | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.458 | |
| 3iah | NAP | Putative oxoacyl-(Acyl carrier protein) reductase | / | 0.458 | |
| 3k5g | BJC | Beta-secretase 1 | 3.4.23.46 | 0.458 | |
| 4an4 | DUD | Putative glycosyl transferase | / | 0.458 | |
| 4b8z | NAP | GDP-L-fucose synthase | 1.1.1.271 | 0.458 | |
| 4d04 | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.458 | |
| 4egb | NAD | dTDP-glucose 4,6-dehydratase | / | 0.458 | |
| 1wnt | NAP | L-xylulose reductase | 1.1.1.10 | 0.457 | |
| 2g1r | 3IG | Renin | 3.4.23.15 | 0.457 | |
| 3pqb | VGP | Putative oxidoreductase | / | 0.457 | |
| 4dc1 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.457 | |
| 4fw8 | NAI | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.457 | |
| 5dbg | NAD | Iridoid synthase | 1.3.1.99 | 0.457 | |
| 1ae1 | NAP | Tropinone reductase 1 | / | 0.456 | |
| 2c20 | NAD | UDP-glucose 4-epimerase | / | 0.456 | |
| 3bhi | NAP | Carbonyl reductase [NADPH] 1 | 1.1.1.184 | 0.456 | |
| 3to6 | LYS_CMC | Histone acetyltransferase ESA1 | / | 0.456 | |
| 4bcr | WY1 | Peroxisome proliferator-activated receptor alpha | / | 0.456 | |
| 4imp | NDP | Polyketide synthase extender modules 3-4 | / | 0.456 | |
| 4nbw | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.456 | |
| 6cts | CIC | Citrate synthase, mitochondrial | 2.3.3.1 | 0.456 | |
| 1fwm | CB3 | Thymidylate synthase | / | 0.455 | |
| 2hyd | ADP | Putative multidrug export ATP-binding/permease protein SAV1866 | 3.6.3 | 0.455 | |
| 2p5u | NAD | UDP-glucose 4-epimerase | / | 0.455 | |
| 2v16 | C47 | Renin | 3.4.23.15 | 0.455 | |
| 3qlr | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 1bim | 0QB | Renin | 3.4.23.15 | 0.454 | |
| 1mjb | ACO | Histone acetyltransferase ESA1 | / | 0.454 | |
| 2rbe | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.454 | |
| 2wo8 | 023 | Macrophage metalloelastase | 3.4.24.65 | 0.454 | |
| 3vf3 | 0GS | Beta-secretase 1 | 3.4.23.46 | 0.454 | |
| 4wdf | A2P | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.454 | |
| 2g78 | REA | Cellular retinoic acid-binding protein 2 | / | 0.453 | |
| 2ifa | FMN | Uncharacterized protein | / | 0.453 | |
| 2ign | FAD | Pyranose 2-oxidase | / | 0.453 | |
| 2z1q | FAD | Acyl-CoA dehydrogenase | / | 0.453 | |
| 2zfn | ACO | Histone acetyltransferase RTT109 | 2.3.1.48 | 0.453 | |
| 3ecg | 065 | Gag-Pol polyprotein | 3.4.23.47 | 0.453 | |
| 3kjs | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.453 | |
| 3up0 | D7S | aceDAF-12 | / | 0.453 | |
| 4l4x | NDP | AmphI | / | 0.453 | |
| 5dcy | NAP | Iridoid synthase | 1.3.1.99 | 0.453 | |
| 1rne | C60 | Renin | 3.4.23.15 | 0.452 | |
| 2ekp | NAD | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.452 | |
| 2ou2 | ACO | Histone acetyltransferase KAT5 | / | 0.452 | |
| 2v13 | C40 | Renin | 3.4.23.15 | 0.452 | |
| 2wf4 | ZY4 | Beta-secretase 1 | 3.4.23.46 | 0.452 | |
| 3jw2 | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.452 | |
| 3k5c | 0BI | Beta-secretase 1 | 3.4.23.46 | 0.452 | |
| 3oho | Z79 | Stromelysin-1 | 3.4.24.17 | 0.452 | |
| 3zbz | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.452 | |
| 4bft | ZVT | Pantothenate kinase | 2.7.1.33 | 0.452 | |
| 4bix | ADP | Sensor histidine kinase CpxA | / | 0.452 | |
| 4dx9 | SER_ALA_VAL_THR | Integrin beta-1 | / | 0.452 | |
| 4dx9 | SER_ALA_VAL_THR | Integrin beta-1-binding protein 1 | / | 0.452 | |
| 4rf2 | NAP | NADPH dependent R-specific alcohol dehydrogenase | / | 0.452 | |
| 1gco | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.451 | |
| 2hps | CTZ | Ca2+-triggered coelenterazine-binding protein 1 | / | 0.451 | |
| 3cz7 | ACO | Histone acetyltransferase RTT109 | 2.3.1.48 | 0.451 | |
| 3tda | PN0 | Cytochrome P450 2D6 | / | 0.451 | |
| 4at0 | FAD | Possible succinate dehydrogenase | / | 0.451 | |
| 4ge7 | 0K5 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.451 | |
| 5af7 | FAD | Acyl-CoA dehydrogenase | / | 0.451 | |
| 2xlr | FAD | Putative flavin-containing monooxygenase | / | 0.450 | |
| 3etd | NDP | Glutamate dehydrogenase 1, mitochondrial | 1.4.1.3 | 0.450 | |
| 3own | 3OW | Renin | 3.4.23.15 | 0.450 | |
| 3syi | FAD | Sulfide-quinone reductase | / | 0.450 | |
| 3u9f | CLM | Chloramphenicol acetyltransferase | 2.3.1.28 | 0.450 | |
| 4amb | DUD | Putative glycosyl transferase | / | 0.450 | |
| 4fj1 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.450 | |
| 1cyd | NDP | Carbonyl reductase [NADPH] 2 | 1.1.1.184 | 0.449 | |
| 1gee | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.449 | |
| 1rwb | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.449 | |
| 1trg | CB3 | Thymidylate synthase | / | 0.449 | |
| 2c59 | NAD | GDP-mannose 3,5-epimerase | 5.1.3.18 | 0.449 | |
| 2iw5 | FAD | Lysine-specific histone demethylase 1A | 1 | 0.449 | |
| 2v6g | NAP | 3-oxo-Delta(4,5)-steroid 5-beta-reductase | / | 0.449 | |
| 2xvf | FAD | Putative flavin-containing monooxygenase | / | 0.449 | |
| 2yph | QQY | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.449 | |
| 3cos | NAD | Alcohol dehydrogenase 4 | 1.1.1.1 | 0.449 | |
| 3lpk | Z76 | Beta-secretase 1 | 3.4.23.46 | 0.449 | |
| 4ejm | NAP | Putative zinc-binding dehydrogenase | / | 0.449 | |
| 4j7u | NAP | Sepiapterin reductase | 1.1.1.153 | 0.449 | |
| 1blz | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.448 | |
| 1e3e | NAI | Alcohol dehydrogenase 4 | 1.1.1.1 | 0.448 | |
| 1pr9 | NAP | L-xylulose reductase | 1.1.1.10 | 0.448 | |
| 1zem | NAD | Xylitol dehydrogenase | / | 0.448 | |
| 2giv | ACO | Histone acetyltransferase KAT8 | / | 0.448 | |
| 2i4q | UA4 | Renin | 3.4.23.15 | 0.448 | |
| 2rjp | 886 | A disintegrin and metalloproteinase with thrombospondin motifs 4 | 3.4.24.82 | 0.448 | |
| 5hes | 032 | Mitogen-activated protein kinase kinase kinase 20 | 2.7.11.25 | 0.448 | |
| 1biw | S80 | Stromelysin-1 | 3.4.24.17 | 0.447 | |
| 1g0n | NDP | Tetrahydroxynaphthalene reductase | 1.1.1.252 | 0.447 | |
| 1o97 | FAD | Electron transfer flavoprotein subunit alpha | / | 0.447 | |
| 1xs7 | MMI | Beta-secretase 1 | 3.4.23.46 | 0.447 | |
| 2pg0 | FAD | Acyl-CoA dehydrogenase | / | 0.447 | |
| 3ge6 | FMN | Nitroreductase | / | 0.447 | |
| 3kpk | FAD | Sulfide-quinone reductase | / | 0.447 | |
| 3q33 | ACO | Histone acetyltransferase RTT109 | 2.3.1.48 | 0.447 | |
| 4dmm | NAP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.447 | |
| 4fr4 | STU | Serine/threonine-protein kinase 32A | 2.7.11.1 | 0.447 | |
| 4j0v | 1H7 | Beta-secretase 1 | 3.4.23.46 | 0.447 | |
| 4z5w | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.447 | |
| 1cf3 | FAD | Glucose oxidase | 1.1.3.4 | 0.446 | |
| 1ja0 | FMN | NADPH--cytochrome P450 reductase | / | 0.446 | |
| 1mja | COA | Histone acetyltransferase ESA1 | / | 0.446 | |
| 1rx0 | FAD | Isobutyryl-CoA dehydrogenase, mitochondrial | 1.3.99 | 0.446 | |
| 1w4x | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.446 | |
| 1w6h | TIT | Plasmepsin-2 | 3.4.23.39 | 0.446 | |
| 2b37 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.446 | |
| 2b3d | FAD | Modulator of drug activity B | / | 0.446 | |
| 2fto | CB3 | Thymidylate synthase | / | 0.446 | |
| 2ylr | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.446 | |
| 3gdp | FAD | (R)-mandelonitrile lyase 2 | 4.1.2.10 | 0.446 | |
| 3p2e | SAH | 16S rRNA (adenine(1408)-N(1))-methyltransferase | 2.1.1.180 | 0.446 | |
| 3q43 | D66 | M1 family aminopeptidase | 3.4.11 | 0.446 | |
| 3r7k | FDA | Probable acyl CoA dehydrogenase | / | 0.446 | |
| 3slz | 3TL | Putative gag-pro-pol polyprotein | / | 0.446 | |
| 4exg | 916 | Beta-secretase 1 | 3.4.23.46 | 0.446 | |
| 4iql | FMN | Enoyl-(Acyl-carrier-protein) reductase II | / | 0.446 | |
| 1di8 | DTQ | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.445 | |
| 1ege | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.445 | |
| 1mv8 | GDX | GDP-mannose 6-dehydrogenase | 1.1.1.132 | 0.445 | |
| 1pqc | 444 | Oxysterols receptor LXR-beta | / | 0.445 | |
| 1teh | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.445 | |
| 1vl8 | NAP | Oxidoreductase, short chain dehydrogenase/reductase family | / | 0.445 | |
| 2bfq | AR6 | [Protein ADP-ribosylglutamate] hydrolase AF_1521 | 3.2.2 | 0.445 | |
| 2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.445 | |
| 2qn7 | HBZ | Glycogen phosphorylase, muscle form | 2.4.1.1 | 0.445 | |
| 2wes | FAD | Tryptophan 5-halogenase | / | 0.445 | |
| 3aw9 | NAD | NAD-dependent epimerase/dehydratase | / | 0.445 | |
| 3cid | 318 | Beta-secretase 1 | 3.4.23.46 | 0.445 | |
| 3eks | CY9 | Actin-5C | / | 0.445 | |
| 3fpz | AHZ | Thiamine thiazole synthase | / | 0.445 | |
| 3gqv | NAP | Enoyl reductase LovC | 1 | 0.445 | |
| 3gy0 | NAP | NAD(P)-dependent oxidoreductase | / | 0.445 | |
| 3lsm | SFD | Pyranose 2-oxidase | / | 0.445 | |
| 3s3r | 0IW | Cathepsin B-like peptidase (C01 family) | / | 0.445 | |
| 3sz0 | FAD | Sulfide-quinone reductase | / | 0.445 | |
| 3vsx | R32 | Renin | 3.4.23.15 | 0.445 | |
| 4fj2 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.445 | |
| 4tm0 | NAP | KtzI | / | 0.445 | |
| 5jla | NAD | Putative short-chain dehydrogenase/reductase | / | 0.445 | |
| 1qor | NDP | Quinone oxidoreductase 1 | / | 0.444 | |
| 2iqg | F2I | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
| 2j83 | BAT | Ulilysin | 3.4.24 | 0.444 | |
| 3bgx | MEF | Thymidylate synthase | / | 0.444 | |
| 3ekp | 478 | Gag-Pol polyprotein | 3.4.23.16 | 0.444 | |
| 3ixj | 586 | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
| 3zuy | TCH | Transporter | / | 0.444 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.444 | |
| 4eso | NAP | Putative oxidoreductase | / | 0.444 | |
| 4j7x | NAP | Sepiapterin reductase | 1.1.1.153 | 0.444 | |
| 1drf | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 1hon | GNH | Adenylosuccinate synthetase | / | 0.443 | |
| 1ppj | ANY | Cytochrome b | / | 0.443 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
| 3ohh | 3HH | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 3t14 | FAD | Sulfide-quinone reductase | / | 0.443 | |
| 4l7j | 1W2 | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 4yry | FAD | Glutamate synthase, beta subunit | / | 0.443 | |
| 5idw | NAP | Short-chain dehydrogenase/reductase SDR | / | 0.443 | |
| 1qlh | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.442 | |
| 2d1y | NAD | Oxidoreductase, short-chain dehydrogenase/reductase family | / | 0.442 | |
| 2g1y | 5IG | Renin | 3.4.23.15 | 0.442 | |
| 2g8y | NAD | Hydroxycarboxylate dehydrogenase B | / | 0.442 | |
| 2gev | COK | Pantothenate kinase | 2.7.1.33 | 0.442 | |
| 2iko | 7IG | Renin | 3.4.23.15 | 0.442 | |
| 2jbs | FMN | p-hydroxyphenylacetate 3-hydroxylase, oxygenase component | / | 0.442 | |
| 2p83 | MR0 | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 3cyw | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.442 | |
| 3g5s | FAD | Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO | / | 0.442 | |
| 3jyn | NDP | Quinone oxidoreductase | / | 0.442 | |
| 3l5d | BDV | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 3nug | NAD | Pyridoxal 4-dehydrogenase | 1.1.1.107 | 0.442 | |
| 3p4t | FAO | Putative acyl-CoA dehydrogenase | / | 0.442 | |
| 3p6o | ETG | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 3qv1 | NAD | Glyceraldehyde-3-phosphate dehydrogenase GAPA1, chloroplastic | 1.2.1.13 | 0.442 | |
| 3vsw | R31 | Renin | 3.4.23.15 | 0.442 | |
| 3w8d | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.442 | |
| 4fx9 | FAD | Coenzyme A disulfide reductase | 1.8.1.14 | 0.442 | |
| 4gl4 | NAI | Alcohol dehydrogenase class-3 | / | 0.442 | |
| 4n6b | COA | Uncharacterized protein | / | 0.442 | |
| 4yai | NAI | C alpha-dehydrogenase | / | 0.442 | |
| 5kjc | NAJ | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.442 | |
| 1u7t | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.441 | |
| 2r0c | FAD | Putative FAD-monooxygenase | / | 0.441 | |
| 3gyu | DL7 | Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily | / | 0.441 | |
| 3ru7 | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.441 | |
| 3ruh | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.441 | |
| 4da8 | BG2 | Purine nucleoside phosphorylase DeoD-type | 2.4.2.1 | 0.441 | |
| 4g9k | FAD | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.441 | |
| 4hfr | 14M | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.441 | |
| 4px9 | ADP | ATP-dependent RNA helicase DDX3X | 3.6.4.13 | 0.441 | |
| 5dbj | FAD | FADH2-dependent halogenase PltA | / | 0.441 | |
| 1eve | E20 | Acetylcholinesterase | 3.1.1.7 | 0.440 | |
| 1g1a | NAD | dTDP-glucose 4,6-dehydratase | / | 0.440 | |
| 1ju2 | FAD | (R)-mandelonitrile lyase 2 | 4.1.2.10 | 0.440 | |
| 1lua | NAP | Bifunctional protein MdtA | 1.5.1.5 | 0.440 | |
| 1mp0 | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.440 | |
| 1w4z | NAP | Putative ketoacyl reductase | 1.3.1 | 0.440 | |
| 1x7h | NDP | Putative ketoacyl reductase | 1.3.1 | 0.440 | |
| 2clq | STU | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.440 | |
| 2eba | FAD | Putative glutaryl-CoA dehydrogenase | / | 0.440 | |
| 2hq9 | FAD | Mll6688 protein | / | 0.440 | |
| 2oy2 | ILE_ALA_GLY | Neutrophil collagenase | 3.4.24.34 | 0.440 | |
| 2p8u | COA | Hydroxymethylglutaryl-CoA synthase, cytoplasmic | 2.3.3.10 | 0.440 | |
| 2vkm | BSD | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 2wf1 | ZY1 | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 2yls | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.440 | |
| 2yut | NAP | Putative short-chain oxidoreductase | / | 0.440 | |
| 3clu | FAD | Electron transfer flavoprotein subunit alpha | / | 0.440 | |
| 3gwd | FAD | Cyclohexanone monooxygenase | / | 0.440 | |
| 3he3 | FAD | UDP-galactopyranose mutase | / | 0.440 | |
| 3hek | BD0 | Heat shock protein HSP 90-alpha | / | 0.440 | |
| 3qaa | G04 | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
| 3qvp | FAD | Glucose oxidase | 1.1.3.4 | 0.440 | |
| 3t2z | FAD | Sulfide-quinone reductase | / | 0.440 | |
| 4mdh | NAD | Malate dehydrogenase, cytoplasmic | 1.1.1.37 | 0.440 | |
| 4qi7 | FAD | Cellobiose dehydrogenase | / | 0.440 | |
| 4tlx | FDA | KtzI | / | 0.440 | |
| 5dqr | FAD | 7-hydroxymethyl chlorophyll a reductase, chloroplastic | 1.17.7.2 | 0.440 |