sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1uhl | MEI | Retinoic acid receptor RXR-beta |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 1uhl | MEI | Retinoic acid receptor RXR-beta | / | 1.000 | |
| 1k74 | 9CR | Retinoic acid receptor RXR-alpha | / | 0.616 | |
| 1fby | REA | Retinoic acid receptor RXR-alpha | / | 0.603 | |
| 3uvv | REA | Retinoic acid receptor RXR-alpha | / | 0.603 | |
| 1fm6 | 9CR | Retinoic acid receptor RXR-alpha | / | 0.597 | |
| 2p1v | 5TN | Retinoic acid receptor RXR-alpha | / | 0.583 | |
| 1rdt | L79 | Retinoic acid receptor RXR-alpha | / | 0.581 | |
| 2p1u | 4TN | Retinoic acid receptor RXR-alpha | / | 0.578 | |
| 3oap | REA | Retinoic acid receptor RXR-alpha | / | 0.577 | |
| 2p1t | 3TN | Retinoic acid receptor RXR-alpha | / | 0.573 | |
| 1mzn | BM6 | Retinoic acid receptor RXR-alpha | / | 0.566 | |
| 4m8h | R4M | Retinoic acid receptor RXR-alpha | / | 0.563 | |
| 4k6i | 9RA | Retinoic acid receptor RXR-alpha | / | 0.562 | |
| 1xls | REA | Retinoic acid receptor RXR-alpha | / | 0.559 | |
| 1mvc | BM6 | Retinoic acid receptor RXR-alpha | / | 0.557 | |
| 1xiu | REA | Retinoic acid receptor RXR | / | 0.556 | |
| 4k4j | 1O8 | Retinoic acid receptor RXR-alpha | / | 0.551 | |
| 4m8e | 29V | Retinoic acid receptor RXR-alpha | / | 0.549 | |
| 3h0a | 9RA | Retinoic acid receptor RXR-alpha | / | 0.546 | |
| 2acl | REA | Retinoic acid receptor RXR-alpha | / | 0.534 | |
| 3fc6 | REA | Retinoic acid receptor RXR-alpha | / | 0.534 | |
| 3fal | REA | Retinoic acid receptor RXR-alpha | / | 0.528 | |
| 1fm9 | 9CR | Retinoic acid receptor RXR-alpha | / | 0.525 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.490 | |
| 2p15 | EZT | Estrogen receptor | / | 0.484 | |
| 2ydo | ADN | Adenosine receptor A2a | / | 0.482 | |
| 4j6d | TES | Cytochrome P450 monooxygenase | / | 0.482 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.479 | |
| 2h55 | DZ8 | Heat shock protein HSP 90-alpha | / | 0.478 | |
| 3njo | PYV | Abscisic acid receptor PYR1 | / | 0.478 | |
| 4qa0 | SHH | Histone deacetylase 8 | 3.5.1.98 | 0.478 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.477 | |
| 3p99 | LNP | Lanosterol 14-alpha-demethylase | / | 0.477 | |
| 3p9t | TCL | Repressor | / | 0.477 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.476 | |
| 3l0l | HC3 | Nuclear receptor ROR-gamma | / | 0.475 | |
| 3lfc | Z86 | Mitogen-activated protein kinase 14 | / | 0.475 | |
| 1pkf | EPD | Epothilone C/D epoxidase | 1.14 | 0.474 | |
| 3rfm | CFF | Adenosine receptor A2a | / | 0.474 | |
| 1og5 | SWF | Cytochrome P450 2C9 | / | 0.473 | |
| 1uzw | CDH | Isopenicillin N synthase | 1.21.3.1 | 0.473 | |
| 2y98 | MIV | Mycinamicin IV hydroxylase/epoxidase | / | 0.473 | |
| 3oaf | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.473 | |
| 4j6c | STR | Cytochrome P450 monooxygenase | / | 0.471 | |
| 3jsu | KA5 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.470 | |
| 1hfq | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.469 | |
| 1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.469 | |
| 1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.469 | |
| 1dhf | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.468 | |
| 2y46 | MIV | Mycinamicin IV hydroxylase/epoxidase | / | 0.468 | |
| 4bfr | J82 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform | 2.7.1.153 | 0.468 | |
| 3byz | H11 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.467 | |
| 4h96 | 14Q | Dihydrofolate reductase | 1.5.1.3 | 0.467 | |
| 4nb6 | 444 | Nuclear receptor ROR-gamma | / | 0.467 | |
| 1q5d | EPB | Epothilone C/D epoxidase | 1.14 | 0.466 | |
| 1w06 | W05 | Isopenicillin N synthase | 1.21.3.1 | 0.466 | |
| 3kjs | DQ1 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.466 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.466 | |
| 4uym | VOR | 14-alpha sterol demethylase Cyp51B | / | 0.466 | |
| 3c0g | 3AM | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.465 | |
| 4j6b | PLO | Cytochrome P450 monooxygenase | / | 0.465 | |
| 4jib | 1L6 | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.465 | |
| 3pwh | ZMA | Adenosine receptor A2a | / | 0.465 | |
| 2fm5 | M99 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.463 | |
| 4jvm | XDI | Estrogen sulfotransferase | 2.8.2.4 | 0.463 | |
| 4kne | 1CY | Dihydrofolate reductase | 1.5.1.3 | 0.463 | |
| 2dqs | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.462 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.462 | |
| 4ajw | VWN | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform | 2.7.1.153 | 0.462 | |
| 4bii | PYW | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.462 | |
| 1e7a | PFL | Serum albumin | / | 0.461 | |
| 1nzy | BCA | 4-chlorobenzoyl coenzyme A dehalogenase | 3.8.1.7 | 0.461 | |
| 1soj | IBM | cGMP-inhibited 3',5'-cyclic phosphodiesterase B | 3.1.4.17 | 0.461 | |
| 1tbb | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.461 | |
| 4equ | G6I | Serine/threonine-protein kinase 10 | 2.7.11.1 | 0.461 | |
| 4p6w | MOF | Glucocorticoid receptor | / | 0.461 | |
| 4ruo | BIV | Vitamin D3 receptor A | / | 0.461 | |
| 2y60 | M8F | Isopenicillin N synthase | 1.21.3.1 | 0.460 | |
| 3ar4 | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.460 | |
| 4lsj | LSJ | Glucocorticoid receptor | / | 0.460 | |
| 1ia3 | TQ5 | Dihydrofolate reductase | 1.5.1.3 | 0.459 | |
| 1rd4 | L08 | Integrin alpha-L | / | 0.459 | |
| 1u2g | APR | NAD(P) transhydrogenase subunit alpha part 1 | 1.6.1.2 | 0.459 | |
| 1xdk | REA | Retinoic acid receptor beta | / | 0.459 | |
| 2hw2 | RFP | Rifampin ADP-ribosyl transferase | / | 0.459 | |
| 5d7q | 4I5 | NAD-dependent protein deacetylase sirtuin-2 | 3.5.1 | 0.459 | |
| 3rey | XAC | Adenosine receptor A2a | / | 0.459 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.458 | |
| 3inv | C50 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.458 | |
| 4fjz | 4FJ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.458 | |
| 4j4v | SVR | Nucleocapsid protein | / | 0.458 | |
| 5bn4 | ANP | V-type ATP synthase alpha chain | / | 0.458 | |
| 1y2d | 4DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.457 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.457 | |
| 3irn | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.457 | |
| 4fjy | FJY | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.457 | |
| 5d1b | TSN | Histone deacetylase 8 | 3.5.1.98 | 0.457 | |
| 1hb3 | SCV | Isopenicillin N synthase | 1.21.3.1 | 0.456 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.456 | |
| 2w0b | CMW | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.456 | |
| 3tda | PN0 | Cytochrome P450 2D6 | / | 0.456 | |
| 4l9q | 9TP | Serum albumin | / | 0.456 | |
| 1blz | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.455 | |
| 2y6f | M9F | Isopenicillin N synthase | 1.21.3.1 | 0.455 | |
| 2ydv | NEC | Adenosine receptor A2a | / | 0.455 | |
| 3cv9 | VDX | Vitamin D3 dihydroxylase | / | 0.455 | |
| 3qlw | N22 | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 4cd2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 4jlj | 1NM | Deoxycytidine kinase | 2.7.1.74 | 0.455 | |
| 4xoq | F42 | Coenzyme F420:L-glutamate ligase | / | 0.455 | |
| 3uza | T4G | Adenosine receptor A2a | / | 0.455 | |
| 1mkd | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.454 | |
| 1so2 | 666 | cGMP-inhibited 3',5'-cyclic phosphodiesterase B | 3.1.4.17 | 0.454 | |
| 2drc | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 3dga | RJ1 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.454 | |
| 3h1v | TK1 | Glucokinase | 2.7.1.2 | 0.454 | |
| 4ap1 | NAP | Steroid monooxygenase | / | 0.454 | |
| 4h97 | 53S | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 5dc5 | B3N | Histone deacetylase 8 | 3.5.1.98 | 0.454 | |
| 3qak | UKA | Adenosine receptor A2a | / | 0.454 | |
| 2w3v | TOP | Dihydrofolate reductase | / | 0.453 | |
| 2x7h | PFN | Prostaglandin reductase 3 | 1 | 0.453 | |
| 3ar5 | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.453 | |
| 3ar6 | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.453 | |
| 3iro | 2CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.453 | |
| 3qly | 55V | Uncharacterized protein | / | 0.453 | |
| 3u8h | BHP | Phospholipase A2, membrane associated | / | 0.453 | |
| 3um5 | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.453 | |
| 1tsd | F89 | Thymidylate synthase | / | 0.452 | |
| 2gpv | OHT | Estrogen-related receptor gamma | / | 0.452 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.452 | |
| 2vxo | XMP | GMP synthase [glutamine-hydrolyzing] | 6.3.5.2 | 0.452 | |
| 3cd2 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 3eig | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 3qm4 | PN0 | Cytochrome P450 2D6 | / | 0.452 | |
| 3zku | HCV | Isopenicillin N synthase | 1.21.3.1 | 0.452 | |
| 1uyc | PU7 | Heat shock protein HSP 90-alpha | / | 0.451 | |
| 1uyd | PU8 | Heat shock protein HSP 90-alpha | / | 0.451 | |
| 2chw | 039 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.451 | |
| 2pnu | ENM | Androgen receptor | / | 0.451 | |
| 3nr4 | PYV | Abscisic acid receptor PYL2 | / | 0.451 | |
| 3nrr | D16 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.451 | |
| 3zze | 6XP | Hepatocyte growth factor receptor | 2.7.10.1 | 0.451 | |
| 4c3y | ANB | 3-ketosteroid dehydrogenase | / | 0.451 | |
| 1ivr | CBA | Aspartate aminotransferase, mitochondrial | 2.6.1.1 | 0.450 | |
| 1ysx | 4EB | Serum albumin | / | 0.450 | |
| 2agv | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.450 | |
| 2bu9 | HFV | Isopenicillin N synthase | 1.21.3.1 | 0.450 | |
| 2jc6 | QPP | Calcium/calmodulin-dependent protein kinase type 1D | 2.7.11.17 | 0.450 | |
| 2ouu | 35G | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.450 | |
| 2wo7 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.450 | |
| 3lal | KRV | Gag-Pol polyprotein | 2.7.7.49 | 0.450 | |
| 3lu8 | IQX | Serum albumin | / | 0.450 | |
| 3p3z | P3Z | Putative cytochrome P450 | / | 0.450 | |
| 3qlr | QLR | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 3ssn | MVI | Mycinamicin VI 2''-O-methyltransferase | / | 0.450 | |
| 3t14 | FAD | Sulfide-quinone reductase | / | 0.450 | |
| 3zsh | 469 | Mitogen-activated protein kinase 14 | / | 0.450 | |
| 4fex | 0TO | Aminoglycoside 3'-phosphotransferase AphA1-IAB | / | 0.450 | |
| 4gg5 | 0J3 | Hepatocyte growth factor receptor | 2.7.10.1 | 0.450 | |
| 4hyf | 1AK | Tankyrase-2 | 2.4.2.30 | 0.450 | |
| 4pnm | NU1 | Tankyrase-2 | 2.4.2.30 | 0.450 | |
| 3ctj | 320 | Hepatocyte growth factor receptor | 2.7.10.1 | 0.449 | |
| 4b1f | KRH | Glutamate racemase | / | 0.449 | |
| 4l9k | EHF | Serum albumin | / | 0.449 | |
| 3uzc | T4E | Adenosine receptor A2a | / | 0.449 | |
| 1rf7 | DHF | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 1uyk | PUX | Heat shock protein HSP 90-alpha | / | 0.448 | |
| 2b03 | TUD | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.448 | |
| 2b36 | 5PP | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.448 | |
| 2has | C3O | Vitamin D3 receptor | / | 0.448 | |
| 2pui | ADP | Methylthioribose kinase | 2.7.1.100 | 0.448 | |
| 3d3e | D3E | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.448 | |
| 3l08 | ZIG | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.448 | |
| 3um6 | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.448 | |
| 1s9q | OHT | Estrogen-related receptor gamma | / | 0.447 | |
| 2hb7 | O1C | Vitamin D3 receptor | / | 0.447 | |
| 2o7p | NAP | Riboflavin biosynthesis protein RibD | / | 0.447 | |
| 3ar7 | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.447 | |
| 3csd | EMO | Putative ketoacyl reductase | 1.3.1 | 0.447 | |
| 3irm | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.447 | |
| 3oez | STI | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.447 | |
| 4gh3 | 0EV | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.447 | |
| 1m9m | 6NI | Nitric oxide synthase, endothelial | 1.14.13.39 | 0.446 | |
| 1nce | CB3 | Thymidylate synthase | / | 0.446 | |
| 1vj3 | TAB | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 2fhj | MFN | Formylmethanofuran--tetrahydromethanopterin formyltransferase | 2.3.1.101 | 0.446 | |
| 2fm0 | M98 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.446 | |
| 2fzh | DH1 | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 2pul | ACP | Methylthioribose kinase | 2.7.1.100 | 0.446 | |
| 2qd5 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.446 | |
| 2wpw | ACO | Orf14 | / | 0.446 | |
| 3fzn | D7K | Benzoylformate decarboxylase | 4.1.1.7 | 0.446 | |
| 3o56 | ZG1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.446 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.446 | |
| 4e6a | 0O9 | Mitogen-activated protein kinase 14 | / | 0.446 | |
| 4g95 | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 1tdr | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 2b01 | TUD | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.445 | |
| 3ada | NAD | Subunit alpha of sarocosine oxidase | / | 0.445 | |
| 3ua5 | 06X | Cytochrome P450 2B6 | 1.14.13 | 0.445 | |
| 3zia | ADP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.445 | |
| 4dm6 | TTB | Retinoic acid receptor beta | / | 0.445 | |
| 1uy7 | PU4 | Heat shock protein HSP 90-alpha | / | 0.444 | |
| 1vru | AAP | Gag-Pol polyprotein | 2.7.7.49 | 0.444 | |
| 2h42 | VIA | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.444 | |
| 2jed | LG8 | Protein kinase C theta type | 2.7.11.13 | 0.444 | |
| 2jj2 | ANP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.444 | |
| 2zlc | VDX | Vitamin D3 receptor | / | 0.444 | |
| 3vtd | TKD | Vitamin D3 receptor | / | 0.444 | |
| 4c1i | EH9 | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.444 | |
| 4nc3 | ERM | 5-hydroxytryptamine receptor 2B | / | 0.444 | |
| 1fcx | 184 | Retinoic acid receptor gamma | / | 0.443 | |
| 1q9m | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.443 | |
| 2ham | C33 | Vitamin D3 receptor | / | 0.443 | |
| 2imk | GTX | AGAP009194-PA | / | 0.443 | |
| 2iod | MYC | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.443 | |
| 2ze2 | T27 | Gag-Pol polyprotein | 2.7.7.49 | 0.443 | |
| 3s79 | ASD | Aromatase | 1.14.14.14 | 0.443 | |
| 4bge | PYW | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.443 | |
| 4fny | I3K | ALK tyrosine kinase receptor | 2.7.10.1 | 0.443 | |
| 4h4m | 494 | Gag-Pol polyprotein | 2.7.7.49 | 0.443 | |
| 4h98 | 14Q | Uncharacterized protein | / | 0.443 | |
| 4hw3 | 19G | Induced myeloid leukemia cell differentiation protein Mcl-1 | / | 0.443 | |
| 5iu4 | ZMA | Adenosine receptor A2a | / | 0.443 | |
| 1lhw | ESM | Sex hormone-binding globulin | / | 0.442 | |
| 1xp9 | AIJ | Estrogen receptor | / | 0.442 | |
| 1zkl | IBM | High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A | 3.1.4.53 | 0.442 | |
| 2e9a | B28 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.442 | |
| 2g2h | P16 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.442 | |
| 2hm9 | TRR | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 2qd4 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.442 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.442 | |
| 2uxo | TAC | HTH-type transcriptional regulator TtgR | / | 0.442 | |
| 3g4i | D71 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.442 | |
| 3tub | FPU | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.442 | |
| 4dpd | DHF | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.442 | |
| 4dvq | 1CA | Cytochrome P450 11B2, mitochondrial | 1.14.15.4 | 0.442 | |
| 4few | PP2 | Aminoglycoside 3'-phosphotransferase AphA1-IAB | / | 0.442 | |
| 4ia1 | BIV | Vitamin D3 receptor A | / | 0.442 | |
| 4ia7 | BIV | Vitamin D3 receptor A | / | 0.442 | |
| 4iui | 1GQ | Estrogen receptor | / | 0.442 | |
| 4mfb | 29T | Gag-Pol polyprotein | 2.7.7.49 | 0.442 | |
| 4qa2 | SHH | Histone deacetylase 8 | 3.5.1.98 | 0.442 | |
| 5iu8 | 6DZ | Adenosine receptor A2a | / | 0.442 | |
| 1aoe | GW3 | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 1dr3 | HBI | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 1ly3 | COG | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 1s6q | TPB | Gag-Pol polyprotein | 2.7.7.49 | 0.441 | |
| 3a0i | AJI | Glucokinase | 2.7.1.2 | 0.441 | |
| 3eek | 53S | Uncharacterized protein | / | 0.441 | |
| 3ipq | 965 | Oxysterols receptor LXR-alpha | / | 0.441 | |
| 3is9 | AC7 | Gag-Pol polyprotein | 2.7.7.49 | 0.441 | |
| 3kyt | HC2 | Nuclear receptor ROR-gamma | / | 0.441 | |
| 3s3v | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 3t2y | FAD | Sulfide-quinone reductase | / | 0.441 | |
| 4elb | 34R | Dihydrofolate reductase | / | 0.441 | |
| 4iw8 | KN3 | Estrogen receptor | / | 0.441 | |
| 4l8u | 9AZ | Serum albumin | / | 0.441 | |
| 4o71 | CPB | Bromodomain-containing protein 4 | / | 0.441 | |
| 1exa | 394 | Retinoic acid receptor gamma | / | 0.440 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
| 1xng | DND | NH(3)-dependent NAD(+) synthetase | 6.3.1.5 | 0.440 | |
| 2azy | CHD | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.440 | |
| 2fzi | DH3 | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 2vzm | NRB | Cytochrome P450 monooxygenase PikC | / | 0.440 | |
| 3a1l | 2CC | Cytochrome P450 | / | 0.440 | |
| 3new | 3NE | Mitogen-activated protein kinase 14 | / | 0.440 | |
| 3qaq | QAQ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.440 | |
| 3qdd | 94M | Heat shock protein HSP 90-alpha | / | 0.440 | |
| 4aos | NAP | Steroid monooxygenase | / | 0.440 | |
| 4eev | L1X | Hepatocyte growth factor receptor | 2.7.10.1 | 0.440 | |
| 4o76 | 1M3 | Bromodomain-containing protein 4 | / | 0.440 |