sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Modes are compared using Grim.
For more information, please see the following publication:
Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3wds | NAD | NADH-dependent quinuclidinone reductase |
| PDB ID | HET | Uniprot Name | EC Number | Binding Mode Similarity |
Align |
|---|---|---|---|---|---|
| 3wds | NAD | NADH-dependent quinuclidinone reductase | / | 1.305 | |
| 3ak4 | NAD | NADH-dependent quinuclidinone reductase | / | 1.101 | |
| 5jsf | NAD | 17-beta-hydroxysteroid dehydrogenase 14 | 1.1.1 | 1.029 | |
| 5js6 | NAD | 17-beta-hydroxysteroid dehydrogenase 14 | 1.1.1 | 1.008 | |
| 1edo | NAP | 3-oxoacyl-[acyl-carrier-protein] reductase 1, chloroplastic | 1.1.1.100 | 0.994 | |
| 1geg | NAD | Diacetyl reductase [(S)-acetoin forming] | 1.1.1.304 | 0.983 | |
| 3nug | NAD | Pyridoxal 4-dehydrogenase | 1.1.1.107 | 0.980 | |
| 2gdz | NAD | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | 1.1.1.141 | 0.970 | |
| 3a28 | NAD | L-2,3-butanediol dehydrogenase | 1.1.1.76 | 0.969 | |
| 3w8d | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.969 | |
| 4nbt | NAD | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.962 | |
| 4dc1 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.958 | |
| 2d1y | NAD | Oxidoreductase, short-chain dehydrogenase/reductase family | / | 0.952 | |
| 3w8f | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.944 | |
| 2q2v | NAD | Beta-D-hydroxybutyrate dehydrogenase | / | 0.943 | |
| 3w8e | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.942 | |
| 4b79 | NAD | Probable short-chain dehydrogenase | / | 0.942 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.942 | |
| 1h5q | NAP | NADP-dependent mannitol dehydrogenase | 1.1.1.138 | 0.940 | |
| 3pgx | NAD | Uncharacterized NAD-dependent oxidoreductase MAP_4146 | / | 0.924 | |
| 1x7h | NDP | Putative ketoacyl reductase | 1.3.1 | 0.922 | |
| 4kwh | NAP | Reductase homolog | / | 0.920 | |
| 1vl8 | NAP | Oxidoreductase, short chain dehydrogenase/reductase family | / | 0.913 | |
| 4dc0 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.913 | |
| 3p19 | NDP | Putative blue fluorescent protein | / | 0.911 | |
| 5jla | NAD | Putative short-chain dehydrogenase/reductase | / | 0.911 | |
| 4wec | NAD | Short chain dehydrogenase | / | 0.902 | |
| 2wsb | NAD | Galactitol dehydrogenase | / | 0.899 | |
| 4is3 | NAD | 3alpha-hydroxy bile acid-CoA-ester 3-dehydrogenase 2 | 1.17.98.1 | 0.898 | |
| 4z3d | NDP | Carbonyl reductase [NADPH] 1 | 1.1.1.184 | 0.898 | |
| 3ai2 | NDP | NADPH-sorbose reductase | / | 0.890 | |
| 3vdq | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.888 | |
| 1gee | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.884 | |
| 3qrw | NDP | Putative ketoacyl reductase | 1.3.1 | 0.881 | |
| 3iah | NAP | Putative oxoacyl-(Acyl carrier protein) reductase | / | 0.878 | |
| 4nbu | NAI | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.876 | |
| 4fj0 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.872 | |
| 1g0n | NDP | Tetrahydroxynaphthalene reductase | 1.1.1.252 | 0.870 | |
| 3o26 | NDP | Salutaridine reductase | / | 0.870 | |
| 1e6w | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.868 | |
| 2jah | NDP | Clavaldehyde dehydrogenase | / | 0.865 | |
| 2ztl | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.865 | |
| 4fj2 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.865 | |
| 1n5d | NDP | Carbonyl reductase [NADPH] 1 | / | 0.860 | |
| 3sju | NDP | Keto reductase | / | 0.857 | |
| 1w4z | NAP | Putative ketoacyl reductase | 1.3.1 | 0.855 | |
| 5ig2 | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.855 | |
| 1gco | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.853 | |
| 1nfr | NAD | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.853 | |
| 3rj9 | NAD | Alcohol dehydrogenase | 1.1.1.1 | 0.852 | |
| 1e3s | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.849 | |
| 4iqg | NAP | Short-chain dehydrogenase/reductase SDR | / | 0.849 | |
| 1rwb | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.847 | |
| 3ruc | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.846 | |
| 4fn4 | NAD | Short chain dehydrogenase | / | 0.846 | |
| 3geg | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.845 | |
| 1ipe | NDP | Tropinone reductase 2 | 1.1.1.236 | 0.843 | |
| 1fdu | NAP | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.842 | |
| 3s55 | NAD | Putative short-chain dehydrogenase/reductase | / | 0.842 | |
| 1cyd | NDP | Carbonyl reductase [NADPH] 2 | 1.1.1.184 | 0.841 | |
| 2dte | NAI | Glucose 1-dehydrogenase related protein | / | 0.841 | |
| 4bmv | NAP | Short-chain dehydrogenase | / | 0.840 | |
| 3ruh | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.838 | |
| 1bdb | NAD | Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase | / | 0.837 | |
| 4dmm | NAP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.837 | |
| 4hp8 | NAP | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.837 | |
| 4pvd | NDP | NADPH-dependent methylglyoxal reductase GRE2 | / | 0.837 | |
| 1e3w | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.833 | |
| 2ekp | NAD | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.833 | |
| 4hwk | NAP | Sepiapterin reductase | 1.1.1.153 | 0.833 | |
| 2o23 | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.832 | |
| 3gy0 | NAP | NAD(P)-dependent oxidoreductase | / | 0.830 | |
| 4gh5 | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.828 | |
| 1nff | NAD | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.827 | |
| 1u7t | TDT | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.827 | |
| 2c29 | NAP | Dihydroflavonol 4-reductase | / | 0.824 | |
| 3ruf | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.820 | |
| 5idw | NAP | Short-chain dehydrogenase/reductase SDR | / | 0.820 | |
| 4fj1 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.817 | |
| 4j7u | NAP | Sepiapterin reductase | 1.1.1.153 | 0.816 | |
| 4k6f | NAP | Putative Acetoacetyl-CoA reductase | / | 0.815 | |
| 4rf2 | NAP | NADPH dependent R-specific alcohol dehydrogenase | / | 0.815 | |
| 3qwf | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.814 | |
| 4bms | NAP | Alclohol dehydrogenase/short-chain dehydrogenase | / | 0.814 | |
| 3sx2 | NAD | Uncharacterized protein | / | 0.812 | |
| 4qed | NAP | ElxO | / | 0.810 | |
| 2ztv | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.809 | |
| 3bhi | NAP | Carbonyl reductase [NADPH] 1 | 1.1.1.184 | 0.808 | |
| 2q2q | NAD | Beta-D-hydroxybutyrate dehydrogenase | / | 0.807 | |
| 3d3w | NAP | L-xylulose reductase | 1.1.1.10 | 0.807 | |
| 4qec | NAP | ElxO | / | 0.806 | |
| 1sny | NAP | LD36273p | / | 0.802 | |
| 4yai | NAI | C alpha-dehydrogenase | / | 0.801 | |
| 1pr9 | NAP | L-xylulose reductase | 1.1.1.10 | 0.800 | |
| 1sby | NAD | Alcohol dehydrogenase | 1.1.1.1 | 0.799 | |
| 2y99 | NAD | Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase | 1.3.1.56 | 0.796 | |
| 3ijr | NAD | Oxidoreductase, short chain dehydrogenase/reductase family | / | 0.795 | |
| 4u7w | NDP | MxaA | / | 0.794 | |
| 2ztm | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.792 | |
| 2q1w | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.791 | |
| 3rj5 | NAD | Alcohol dehydrogenase | 1.1.1.1 | 0.791 | |
| 3rku | NAP | NADP-dependent 3-hydroxy acid dehydrogenase | / | 0.790 | |
| 3ru7 | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.787 | |
| 2bd0 | NAP | Sepiapterin reductase | / | 0.786 | |
| 2hrb | NAP | Carbonyl reductase [NADPH] 3 | 1.1.1.184 | 0.786 | |
| 3ai3 | NDP | NADPH-sorbose reductase | / | 0.786 | |
| 3tsc | NAD | Uncharacterized protein | / | 0.786 | |
| 2b4q | NAP | Rhamnolipids biosynthesis 3-oxoacyl-[acyl-carrier-protein] reductase | 1.1.1.100 | 0.785 | |
| 4nbw | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.784 | |
| 4j7x | NAP | Sepiapterin reductase | 1.1.1.153 | 0.782 | |
| 4zju | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.782 | |
| 1xkq | NDP | Uncharacterized protein | / | 0.781 | |
| 1x7g | NAP | Putative ketoacyl reductase | 1.3.1 | 0.780 | |
| 4fc7 | NAP | Peroxisomal 2,4-dienoyl-CoA reductase | 1.3.1.34 | 0.779 | |
| 2c59 | NAD | GDP-mannose 3,5-epimerase | 5.1.3.18 | 0.778 | |
| 2dkn | NAI | 3-alpha-hydroxysteroid dehydrogenase | / | 0.778 | |
| 2wdz | NAD | Galactitol dehydrogenase | / | 0.778 | |
| 1zem | NAD | Xylitol dehydrogenase | / | 0.777 | |
| 2wyv | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.777 | |
| 1b15 | NAE | Alcohol dehydrogenase | 1.1.1.1 | 0.776 | |
| 1oaa | NAP | Sepiapterin reductase | 1.1.1.153 | 0.776 | |
| 3r3s | NAD | Putative oxidoreductase | / | 0.776 | |
| 1b16 | NAQ | Alcohol dehydrogenase | 1.1.1.1 | 0.775 | |
| 3aut | NAI | Glucose 1-dehydrogenase 4 | 1.1.1.47 | 0.775 | |
| 3ko8 | NAD | NAD-dependent epimerase/dehydratase | / | 0.773 | |
| 4yag | NAI | C alpha-dehydrogenase | / | 0.773 | |
| 5d2e | NAP | MlnE | / | 0.773 | |
| 1mg5 | NAI | Alcohol dehydrogenase | 1.1.1.1 | 0.772 | |
| 4lis | NAD | UDP-glucose 4-epimerase (Eurofung) | / | 0.772 | |
| 1ae1 | NAP | Tropinone reductase 1 | / | 0.770 | |
| 1g6k | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.770 | |
| 3ru9 | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.770 | |
| 3rua | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.770 | |
| 2p5u | NAD | UDP-glucose 4-epimerase | / | 0.768 | |
| 3ndr | NAD | Pyridoxal 4-dehydrogenase | 1.1.1.107 | 0.766 | |
| 1xse | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.765 | |
| 1b2l | NDC | Alcohol dehydrogenase | 1.1.1.1 | 0.764 | |
| 2nnl | NAP | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.764 | |
| 4m87 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.763 | |
| 2q1s | NAI | Putative nucleotide sugar epimerase/ dehydratase | / | 0.762 | |
| 3uce | NDP | Dehydrogenase | / | 0.759 | |
| 2idz | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.758 | |
| 2rbe | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.757 | |
| 2ztu | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.757 | |
| 1kvr | NAD | UDP-glucose 4-epimerase | 5.1.3.2 | 0.755 | |
| 3uic | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.751 | |
| 5cpb | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.750 | |
| 1fk8 | NAD | 3-alpha-hydroxysteroid dehydrogenase/carbonyl reductase | 1.1.1.50 | 0.748 | |
| 2q1u | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.748 | |
| 3sj7 | NDP | 3-oxoacyl-(Acyl-carrier-protein) reductase, putative | / | 0.748 | |
| 2c54 | NAD | GDP-mannose 3,5-epimerase | 5.1.3.18 | 0.747 | |
| 1i2b | NAD | UDP-sulfoquinovose synthase, chloroplastic | 3.13.1.1 | 0.746 | |
| 2ag5 | NAD | 3-hydroxybutyrate dehydrogenase type 2 | / | 0.746 | |
| 1u7t | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.745 | |
| 1eny | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.743 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.743 | |
| 3l77 | NJP | Short-chain alcohol dehydrogenase | / | 0.742 | |
| 1orr | NAD | CDP-paratose 2-epimerase | / | 0.739 | |
| 2ntj | P1H | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.738 | |
| 3of2 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.738 | |
| 4oxy | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.738 | |
| 1nah | NAD | UDP-glucose 4-epimerase | 5.1.3.2 | 0.737 | |
| 4i5e | NAP | Alclohol dehydrogenase/short-chain dehydrogenase | / | 0.737 | |
| 1g1a | NAD | dTDP-glucose 4,6-dehydratase | / | 0.735 | |
| 5koi | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.735 | |
| 3sxp | NAD | ADP-L-glycero-D-mannoheptose-6-epimerase | / | 0.734 | |
| 3oey | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.733 | |
| 3tn7 | NJP | Short-chain alcohol dehydrogenase | / | 0.732 | |
| 2p5y | NAD | UDP-glucose 4-epimerase | / | 0.729 | |
| 3rue | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.729 | |
| 5b1y | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.729 | |
| 2bgm | NAJ | Secoisolariciresinol dehydrogenase | 1.1.1.331 | 0.728 | |
| 2pzj | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.728 | |
| 5jy1 | NAD | Putative short-chain dehydrogenase/reductase | / | 0.728 | |
| 2ieb | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.727 | |
| 2b35 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.726 | |
| 2yut | NAP | Putative short-chain oxidoreductase | / | 0.726 | |
| 3rud | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.726 | |
| 1i3l | NAD | UDP-glucose 4-epimerase | / | 0.724 | |
| 4cql | NAD | Estradiol 17-beta-dehydrogenase 8 | 1.1.1.62 | 0.722 | |
| 4idg | NAD | Putative UDP-glucose 4-epimerase | / | 0.722 | |
| 4bii | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.721 | |
| 3oew | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.720 | |
| 1rkx | NAD | CDP-D-glucose-4,6-dehydratase | / | 0.717 | |
| 5jyd | NAD | Short chain dehydrogenase | / | 0.717 | |
| 2aq8 | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.716 | |
| 4trn | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.716 | |
| 2yy7 | NAD | L-threonine dehydrogenase | / | 0.715 | |
| 4gll | NAD | UDP-glucuronic acid decarboxylase 1 | 4.1.1.35 | 0.715 | |
| 1w73 | NAP | 2,4-dienoyl-CoA reductase, mitochondrial | 1.3.1.34 | 0.713 | |
| 4bqp | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.713 | |
| 1bxk | NAD | dTDP-glucose 4,6-dehydratase 2 | / | 0.712 | |
| 2b37 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.712 | |
| 2b69 | NAD | UDP-glucuronic acid decarboxylase 1 | 4.1.1.35 | 0.712 | |
| 3bmo | NAP | Pteridine reductase | / | 0.712 | |
| 3wmx | NAD | NAD dependent epimerase/dehydratase | / | 0.712 | |
| 1qyv | NAP | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.711 | |
| 4dre | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.711 | |
| 4bgi | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.710 | |
| 1xg5 | NAP | Dehydrogenase/reductase SDR family member 11 | / | 0.709 | |
| 3tox | NAP | Putative oxidoreductase | / | 0.709 | |
| 2h9i | EAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.708 | |
| 3o03 | NAP | Dehydrogenase with different specificities (Related to short-chain alcohol dehydrogenase) | / | 0.708 | |
| 4twr | NAD | NAD binding site:NAD-dependent epimerase/dehydratase:UDP-glucose 4-epimerase | / | 0.708 | |
| 2ie0 | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.706 | |
| 4ej0 | NAP | ADP-L-glycero-D-manno-heptose-6-epimerase | / | 0.706 | |
| 3a9w | NAD | NDP-sugar epimerase | / | 0.705 | |
| 4dti | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.705 | |
| 4egb | NAD | dTDP-glucose 4,6-dehydratase | / | 0.705 | |
| 4yac | NAI | C alpha-dehydrogenase | / | 0.705 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.701 | |
| 4n5n | NAP | Acetoacetyl-CoA reductase | 1.1.1.36 | 0.700 | |
| 1i36 | NAP | Conserved protein | / | 0.699 | |
| 1n7h | NDP | GDP-mannose 4,6 dehydratase 2 | 4.2.1.47 | 0.699 | |
| 1ahh | NAD | 7-alpha-hydroxysteroid dehydrogenase | 1.1.1.159 | 0.697 | |
| 3aw9 | NAD | NAD-dependent epimerase/dehydratase | / | 0.697 | |
| 1nai | NAD | UDP-glucose 4-epimerase | 5.1.3.2 | 0.695 | |
| 4dqu | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.693 | |
| 2hsd | NAD | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.692 | |
| 3h4v | NAP | Pteridine reductase 1 | 1.5.1.33 | 0.691 | |
| 3lu1 | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.691 | |
| 2nv6 | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.690 | |
| 5c2t | FAD | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial | / | 0.690 | |
| 2p35 | SAH | Trans-aconitate 2-methyltransferase | / | 0.686 | |
| 1enz | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.685 | |
| 2z1m | NDP | GDP-mannose 4,6-dehydratase | / | 0.685 | |
| 3icp | NAD | NAD-dependent epimerase/dehydratase | / | 0.685 | |
| 1ek5 | NAD | UDP-glucose 4-epimerase | / | 0.684 | |
| 5lc1 | NAD | L-threonine 3-dehydrogenase | / | 0.684 | |
| 1b14 | NAD | Alcohol dehydrogenase | 1.1.1.1 | 0.683 | |
| 3g49 | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.683 | |
| 2aqi | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.680 | |
| 1eq2 | NAP | ADP-L-glycero-D-manno-heptose-6-epimerase | / | 0.676 | |
| 4c4o | NAD | SADH | / | 0.676 | |
| 4hbg | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | 1.1.1.100 | 0.676 | |
| 2aqh | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.675 | |
| 4o0l | NDP | NADPH-dependent 3-quinuclidinone reductase | / | 0.675 | |
| 2ntv | P1H | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.674 | |
| 3a4v | NAD | NDP-sugar epimerase | / | 0.674 | |
| 3uxy | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.673 | |
| 1d2h | SAH | Glycine N-methyltransferase | 2.1.1.20 | 0.672 | |
| 3pvz | NAD | UDP-N-acetylglucosamine 4,6-dehydratase | / | 0.672 | |
| 1ht0 | NAD | Alcohol dehydrogenase 1C | 1.1.1.1 | 0.670 | |
| 2ggs | NDP | dTDP-4-dehydrorhamnose reductase | / | 0.670 | |
| 3ajr | NAD | NDP-sugar epimerase | / | 0.670 | |
| 4fw8 | NAI | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.669 | |
| 1n7g | NDP | GDP-mannose 4,6 dehydratase 2 | 4.2.1.47 | 0.668 | |
| 2ewm | NAD | (S)-1-Phenylethanol dehydrogenase | 1.1.1.311 | 0.668 | |
| 4lk3 | NAD | UDP-glucuronic acid decarboxylase 1 | 4.1.1.35 | 0.668 | |
| 4bkq | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.667 | |
| 4o1m | NAD | Enoyl-acyl carrier reductase | / | 0.667 | |
| 1rpn | NDP | GDP-mannose 4,6-dehydratase | / | 0.666 | |
| 2aqk | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.666 | |
| 2qe6 | SAM | Uncharacterized protein | / | 0.666 | |
| 3wfj | NAD | 2-dehydropantoate 2-reductase | / | 0.666 | |
| 4b8z | NAP | GDP-L-fucose synthase | 1.1.1.271 | 0.666 | |
| 2yw9 | NAP | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.665 | |
| 2xdo | FAD | TetX family tetracycline inactivation enzyme | / | 0.662 | |
| 1uxj | NAD | Malate dehydrogenase | / | 0.660 | |
| 3ehe | NAD | UDP-glucose 4-epimerase (GalE-1) | / | 0.660 | |
| 2i9p | NAD | 3-hydroxyisobutyrate dehydrogenase, mitochondrial | 1.1.1.31 | 0.659 | |
| 3w6u | NAP | 6-phosphogluconate dehydrogenase, NAD-binding protein | / | 0.659 | |
| 1n2s | NAI | dTDP-4-dehydrorhamnose reductase | 1.1.1.133 | 0.658 | |
| 4xb2 | NDP | 319aa long hypothetical homoserine dehydrogenase | / | 0.658 | |
| 3wsw | NAD | L-lactate dehydrogenase | / | 0.657 | |
| 2ydx | NAP | Methionine adenosyltransferase 2 subunit beta | / | 0.656 | |
| 3f1k | NAP | Uncharacterized oxidoreductase YciK | 1 | 0.655 | |
| 1aqi | SAH | Modification methylase TaqI | 2.1.1.72 | 0.654 | |
| 3uj7 | SAM | Phosphoethanolamine N-methyltransferase | / | 0.654 | |
| 5hws | NAP | 2-dehydropantoate 2-reductase | / | 0.654 | |
| 3pdu | NAP | Glyoxalate/3-oxopropanoate/4-oxobutanoate reductase | / | 0.653 | |
| 4b8w | NAP | GDP-L-fucose synthase | 1.1.1.271 | 0.653 | |
| 1rp0 | AHZ | Thiamine thiazole synthase, chloroplastic | / | 0.652 | |
| 3orf | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.652 | |
| 1vrw | NAI | Enoyl-ACP reductase | / | 0.651 |