sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Modes are compared using Grim.
For more information, please see the following publication:
Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3rj5 | NAD | Alcohol dehydrogenase | 1.1.1.1 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Mode Similarity |
Align |
|---|---|---|---|---|---|
| 3rj5 | NAD | Alcohol dehydrogenase | 1.1.1.1 | 1.244 | |
| 3rj9 | NAD | Alcohol dehydrogenase | 1.1.1.1 | 1.141 | |
| 1mg5 | NAI | Alcohol dehydrogenase | 1.1.1.1 | 1.108 | |
| 1b15 | NAE | Alcohol dehydrogenase | 1.1.1.1 | 1.100 | |
| 1b16 | NAQ | Alcohol dehydrogenase | 1.1.1.1 | 1.086 | |
| 1b2l | NDC | Alcohol dehydrogenase | 1.1.1.1 | 1.018 | |
| 1sby | NAD | Alcohol dehydrogenase | 1.1.1.1 | 0.935 | |
| 1b14 | NAD | Alcohol dehydrogenase | 1.1.1.1 | 0.931 | |
| 4z3d | NDP | Carbonyl reductase [NADPH] 1 | 1.1.1.184 | 0.901 | |
| 3w8d | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.894 | |
| 5js6 | NAD | 17-beta-hydroxysteroid dehydrogenase 14 | 1.1.1 | 0.888 | |
| 3nug | NAD | Pyridoxal 4-dehydrogenase | 1.1.1.107 | 0.887 | |
| 3p19 | NDP | Putative blue fluorescent protein | / | 0.883 | |
| 3vdq | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.883 | |
| 5jsf | NAD | 17-beta-hydroxysteroid dehydrogenase 14 | 1.1.1 | 0.878 | |
| 1x7g | NAP | Putative ketoacyl reductase | 1.3.1 | 0.871 | |
| 3w8f | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.867 | |
| 4b79 | NAD | Probable short-chain dehydrogenase | / | 0.867 | |
| 4o0l | NDP | NADPH-dependent 3-quinuclidinone reductase | / | 0.864 | |
| 2o23 | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.861 | |
| 1vl8 | NAP | Oxidoreductase, short chain dehydrogenase/reductase family | / | 0.859 | |
| 2wsb | NAD | Galactitol dehydrogenase | / | 0.859 | |
| 3w8e | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.856 | |
| 1w4z | NAP | Putative ketoacyl reductase | 1.3.1 | 0.854 | |
| 3pgx | NAD | Uncharacterized NAD-dependent oxidoreductase MAP_4146 | / | 0.854 | |
| 4fj0 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.848 | |
| 3iah | NAP | Putative oxoacyl-(Acyl carrier protein) reductase | / | 0.846 | |
| 3bhi | NAP | Carbonyl reductase [NADPH] 1 | 1.1.1.184 | 0.840 | |
| 1x7h | NDP | Putative ketoacyl reductase | 1.3.1 | 0.839 | |
| 4fj2 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.839 | |
| 2ztl | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.837 | |
| 5ig2 | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.836 | |
| 1g0n | NDP | Tetrahydroxynaphthalene reductase | 1.1.1.252 | 0.834 | |
| 4dc0 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.834 | |
| 2jah | NDP | Clavaldehyde dehydrogenase | / | 0.832 | |
| 2q2v | NAD | Beta-D-hydroxybutyrate dehydrogenase | / | 0.832 | |
| 3tsc | NAD | Uncharacterized protein | / | 0.827 | |
| 4pvd | NDP | NADPH-dependent methylglyoxal reductase GRE2 | / | 0.826 | |
| 1e3w | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.825 | |
| 2gdz | NAD | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | 1.1.1.141 | 0.825 | |
| 4dc1 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.825 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.820 | |
| 3a28 | NAD | L-2,3-butanediol dehydrogenase | 1.1.1.76 | 0.819 | |
| 3ak4 | NAD | NADH-dependent quinuclidinone reductase | / | 0.819 | |
| 3qrw | NDP | Putative ketoacyl reductase | 1.3.1 | 0.817 | |
| 1geg | NAD | Diacetyl reductase [(S)-acetoin forming] | 1.1.1.304 | 0.814 | |
| 4kwh | NAP | Reductase homolog | / | 0.814 | |
| 1gee | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.813 | |
| 1e6w | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.812 | |
| 4zju | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.812 | |
| 4hxy | NDP | Plm1 | / | 0.811 | |
| 1n5d | NDP | Carbonyl reductase [NADPH] 1 | / | 0.810 | |
| 2wdz | NAD | Galactitol dehydrogenase | / | 0.809 | |
| 2c29 | NAP | Dihydroflavonol 4-reductase | / | 0.808 | |
| 1edo | NAP | 3-oxoacyl-[acyl-carrier-protein] reductase 1, chloroplastic | 1.1.1.100 | 0.807 | |
| 2ekp | NAD | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.806 | |
| 3ijr | NAD | Oxidoreductase, short chain dehydrogenase/reductase family | / | 0.806 | |
| 1u7t | TDT | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.805 | |
| 2ztm | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.802 | |
| 3s55 | NAD | Putative short-chain dehydrogenase/reductase | / | 0.801 | |
| 4qec | NAP | ElxO | / | 0.800 | |
| 3sx2 | NAD | Uncharacterized protein | / | 0.799 | |
| 4rf2 | NAP | NADPH dependent R-specific alcohol dehydrogenase | / | 0.799 | |
| 3r3s | NAD | Putative oxidoreductase | / | 0.798 | |
| 1gco | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.797 | |
| 1oaa | NAP | Sepiapterin reductase | 1.1.1.153 | 0.797 | |
| 5cpb | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.797 | |
| 2d1y | NAD | Oxidoreductase, short-chain dehydrogenase/reductase family | / | 0.796 | |
| 2zat | NAP | Dehydrogenase/reductase SDR family member 4 | 1.1.1.184 | 0.796 | |
| 4j7u | NAP | Sepiapterin reductase | 1.1.1.153 | 0.792 | |
| 1h5q | NAP | NADP-dependent mannitol dehydrogenase | 1.1.1.138 | 0.791 | |
| 1nfr | NAD | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.791 | |
| 3wds | NAD | NADH-dependent quinuclidinone reductase | / | 0.791 | |
| 5jla | NAD | Putative short-chain dehydrogenase/reductase | / | 0.791 | |
| 2q2q | NAD | Beta-D-hydroxybutyrate dehydrogenase | / | 0.790 | |
| 3oew | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.790 | |
| 4fn4 | NAD | Short chain dehydrogenase | / | 0.789 | |
| 5idw | NAP | Short-chain dehydrogenase/reductase SDR | / | 0.788 | |
| 2nnl | NAP | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.787 | |
| 3o26 | NDP | Salutaridine reductase | / | 0.782 | |
| 4nbt | NAD | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.782 | |
| 4is3 | NAD | 3alpha-hydroxy bile acid-CoA-ester 3-dehydrogenase 2 | 1.17.98.1 | 0.780 | |
| 4k6f | NAP | Putative Acetoacetyl-CoA reductase | / | 0.780 | |
| 2q1t | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.777 | |
| 4m87 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.777 | |
| 3ai2 | NDP | NADPH-sorbose reductase | / | 0.776 | |
| 3o4r | NAP | Dehydrogenase/reductase SDR family member 4 | 1.1.1.184 | 0.775 | |
| 1zem | NAD | Xylitol dehydrogenase | / | 0.774 | |
| 2p5y | NAD | UDP-glucose 4-epimerase | / | 0.772 | |
| 3ai3 | NDP | NADPH-sorbose reductase | / | 0.772 | |
| 3geg | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.772 | |
| 3l77 | NJP | Short-chain alcohol dehydrogenase | / | 0.772 | |
| 1i3l | NAD | UDP-glucose 4-epimerase | / | 0.771 | |
| 3oey | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.771 | |
| 3of2 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.771 | |
| 2b37 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.770 | |
| 3aut | NAI | Glucose 1-dehydrogenase 4 | 1.1.1.47 | 0.768 | |
| 3lu1 | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.768 | |
| 1nff | NAD | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.767 | |
| 3mje | NDP | AmphB | / | 0.767 | |
| 3tn7 | NJP | Short-chain alcohol dehydrogenase | / | 0.767 | |
| 4gh5 | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.767 | |
| 1eny | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.765 | |
| 2b35 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.765 | |
| 2ztv | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.765 | |
| 3icp | NAD | NAD-dependent epimerase/dehydratase | / | 0.764 | |
| 1fdu | NAP | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.763 | |
| 1ipe | NDP | Tropinone reductase 2 | 1.1.1.236 | 0.763 | |
| 1kvr | NAD | UDP-glucose 4-epimerase | 5.1.3.2 | 0.763 | |
| 4qed | NAP | ElxO | / | 0.763 | |
| 1rkx | NAD | CDP-D-glucose-4,6-dehydratase | / | 0.760 | |
| 1e3s | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.758 | |
| 1rwb | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.758 | |
| 2q1w | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.758 | |
| 3uic | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.758 | |
| 2q1s | NAI | Putative nucleotide sugar epimerase/ dehydratase | / | 0.755 | |
| 4i5e | NAP | Alclohol dehydrogenase/short-chain dehydrogenase | / | 0.755 | |
| 4wec | NAD | Short chain dehydrogenase | / | 0.755 | |
| 1ae1 | NAP | Tropinone reductase 1 | / | 0.754 | |
| 1u7t | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.754 | |
| 1cyd | NDP | Carbonyl reductase [NADPH] 2 | 1.1.1.184 | 0.753 | |
| 4bii | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.752 | |
| 3ru7 | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.751 | |
| 4lis | NAD | UDP-glucose 4-epimerase (Eurofung) | / | 0.751 | |
| 4nbu | NAI | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.751 | |
| 4dmm | NAP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.750 | |
| 3ko8 | NAD | NAD-dependent epimerase/dehydratase | / | 0.749 | |
| 2ag5 | NAD | 3-hydroxybutyrate dehydrogenase type 2 | / | 0.748 | |
| 4bmv | NAP | Short-chain dehydrogenase | / | 0.748 | |
| 2ntj | P1H | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.747 | |
| 2wyv | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.746 | |
| 2ztu | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.746 | |
| 3qwf | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.746 | |
| 1i2b | NAD | UDP-sulfoquinovose synthase, chloroplastic | 3.13.1.1 | 0.743 | |
| 3ruc | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.743 | |
| 2ieb | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.740 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.738 | |
| 4hp8 | NAP | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.738 | |
| 5d2e | NAP | MlnE | / | 0.738 | |
| 2bd0 | NAP | Sepiapterin reductase | / | 0.737 | |
| 5koi | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.737 | |
| 2q1u | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.736 | |
| 2aqh | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.734 | |
| 3ruf | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.734 | |
| 3ru9 | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.733 | |
| 4bqp | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.733 | |
| 4fj1 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.733 | |
| 4yag | NAI | C alpha-dehydrogenase | / | 0.732 | |
| 4trn | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.731 | |
| 4j7x | NAP | Sepiapterin reductase | 1.1.1.153 | 0.730 | |
| 2nv6 | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.729 | |
| 3ruh | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.729 | |
| 3tox | NAP | Putative oxidoreductase | / | 0.729 | |
| 3o03 | NAP | Dehydrogenase with different specificities (Related to short-chain alcohol dehydrogenase) | / | 0.728 | |
| 3sxp | NAD | ADP-L-glycero-D-mannoheptose-6-epimerase | / | 0.727 | |
| 1nah | NAD | UDP-glucose 4-epimerase | 5.1.3.2 | 0.726 | |
| 1xse | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.726 | |
| 3h4v | NAP | Pteridine reductase 1 | 1.5.1.33 | 0.725 | |
| 1pr9 | NAP | L-xylulose reductase | 1.1.1.10 | 0.724 | |
| 2idz | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.724 | |
| 2aqk | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.723 | |
| 2c54 | NAD | GDP-mannose 3,5-epimerase | 5.1.3.18 | 0.723 | |
| 1orr | NAD | CDP-paratose 2-epimerase | / | 0.721 | |
| 2y99 | NAD | Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase | 1.3.1.56 | 0.721 | |
| 4gll | NAD | UDP-glucuronic acid decarboxylase 1 | 4.1.1.35 | 0.721 | |
| 1fk8 | NAD | 3-alpha-hydroxysteroid dehydrogenase/carbonyl reductase | 1.1.1.50 | 0.720 | |
| 4dti | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.720 | |
| 4oxy | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.720 | |
| 2aq8 | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.718 | |
| 2p5u | NAD | UDP-glucose 4-epimerase | / | 0.718 | |
| 2yy7 | NAD | L-threonine dehydrogenase | / | 0.718 | |
| 2dkn | NAI | 3-alpha-hydroxysteroid dehydrogenase | / | 0.717 | |
| 3orf | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.717 | |
| 3sju | NDP | Keto reductase | / | 0.716 | |
| 3gy0 | NAP | NAD(P)-dependent oxidoreductase | / | 0.715 | |
| 2aqi | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.714 | |
| 2rbe | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.714 | |
| 2ie0 | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.713 | |
| 3ndr | NAD | Pyridoxal 4-dehydrogenase | 1.1.1.107 | 0.713 | |
| 2dte | NAI | Glucose 1-dehydrogenase related protein | / | 0.712 | |
| 2pzj | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.711 | |
| 3rua | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.711 | |
| 3rud | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.707 | |
| 5lc1 | NAD | L-threonine 3-dehydrogenase | / | 0.707 | |
| 1p44 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.706 | |
| 1xkq | NDP | Uncharacterized protein | / | 0.706 | |
| 3d3w | NAP | L-xylulose reductase | 1.1.1.10 | 0.706 | |
| 4ej0 | NAP | ADP-L-glycero-D-manno-heptose-6-epimerase | / | 0.706 | |
| 2c59 | NAD | GDP-mannose 3,5-epimerase | 5.1.3.18 | 0.705 | |
| 4iqg | NAP | Short-chain dehydrogenase/reductase SDR | / | 0.705 | |
| 1bdb | NAD | Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase | / | 0.704 | |
| 4cql | NAD | Estradiol 17-beta-dehydrogenase 8 | 1.1.1.62 | 0.704 | |
| 5jy1 | NAD | Putative short-chain dehydrogenase/reductase | / | 0.704 | |
| 2yut | NAP | Putative short-chain oxidoreductase | / | 0.703 | |
| 4o1m | NAD | Enoyl-acyl carrier reductase | / | 0.702 | |
| 2ggs | NDP | dTDP-4-dehydrorhamnose reductase | / | 0.701 | |
| 2yw9 | NAP | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.701 | |
| 1xg5 | NAP | Dehydrogenase/reductase SDR family member 11 | / | 0.700 | |
| 4nbw | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.700 | |
| 1sny | NAP | LD36273p | / | 0.697 | |
| 3rue | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.697 | |
| 1n7h | NDP | GDP-mannose 4,6 dehydratase 2 | 4.2.1.47 | 0.696 | |
| 1qyv | NAP | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.695 | |
| 3a9w | NAD | NDP-sugar epimerase | / | 0.695 | |
| 3uxy | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.695 | |
| 4dre | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.695 | |
| 4u7w | NDP | MxaA | / | 0.695 | |
| 1g6k | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.694 | |
| 4hwk | NAP | Sepiapterin reductase | 1.1.1.153 | 0.694 | |
| 1nai | NAD | UDP-glucose 4-epimerase | 5.1.3.2 | 0.693 | |
| 4fc7 | NAP | Peroxisomal 2,4-dienoyl-CoA reductase | 1.3.1.34 | 0.692 | |
| 5jyd | NAD | Short chain dehydrogenase | / | 0.691 | |
| 4yai | NAI | C alpha-dehydrogenase | / | 0.690 | |
| 2y05 | NAP | Prostaglandin reductase 1 | / | 0.688 | |
| 3sj7 | NDP | 3-oxoacyl-(Acyl-carrier-protein) reductase, putative | / | 0.688 | |
| 1g1a | NAD | dTDP-glucose 4,6-dehydratase | / | 0.687 | |
| 4imp | NDP | Polyketide synthase extender modules 3-4 | / | 0.687 | |
| 2b69 | NAD | UDP-glucuronic acid decarboxylase 1 | 4.1.1.35 | 0.686 | |
| 2bgm | NAJ | Secoisolariciresinol dehydrogenase | 1.1.1.331 | 0.686 | |
| 4lk3 | NAD | UDP-glucuronic acid decarboxylase 1 | 4.1.1.35 | 0.686 | |
| 3ehe | NAD | UDP-glucose 4-epimerase (GalE-1) | / | 0.685 | |
| 1wvg | APR | CDP-glucose 4,6-dehydratase | 4.2.1.45 | 0.681 | |
| 4idg | NAD | Putative UDP-glucose 4-epimerase | / | 0.681 | |
| 4egb | NAD | dTDP-glucose 4,6-dehydratase | / | 0.680 | |
| 1rpn | NDP | GDP-mannose 4,6-dehydratase | / | 0.676 | |
| 2z1m | NDP | GDP-mannose 4,6-dehydratase | / | 0.676 | |
| 3u4c | NDP | NADPH-dependent reductase BacG | / | 0.676 | |
| 3a4v | NAD | NDP-sugar epimerase | / | 0.672 | |
| 4bgi | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.671 | |
| 1n2s | NAI | dTDP-4-dehydrorhamnose reductase | 1.1.1.133 | 0.670 | |
| 1hyh | NAD | L-2-hydroxyisocaproate dehydrogenase | / | 0.669 | |
| 2ntv | P1H | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.669 | |
| 3ajr | NAD | NDP-sugar epimerase | / | 0.669 | |
| 3rku | NAP | NADP-dependent 3-hydroxy acid dehydrogenase | / | 0.668 | |
| 3zu2 | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.667 | |
| 2c20 | NAD | UDP-glucose 4-epimerase | / | 0.666 | |
| 3qvs | NAD | Myo-inositol-1-phosphate synthase (Ino1) | / | 0.665 | |
| 3pef | NAP | Glyoxalate/3-oxopropanoate/4-oxobutanoate reductase | / | 0.662 | |
| 3iup | NDP | Possible NADH oxidoreductase | / | 0.661 | |
| 1enz | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.660 | |
| 2g76 | NAD | D-3-phosphoglycerate dehydrogenase | 1.1.1.95 | 0.660 | |
| 1j5p | NAD | L-aspartate dehydrogenase | 1.4.1.21 | 0.658 | |
| 1p9b | IMO | Adenylosuccinate synthetase | / | 0.658 | |
| 2b36 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.658 | |
| 4bkq | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.658 | |
| 4eue | NAI | Trans-2-enoyl-CoA reductase [NADH] | / | 0.658 | |
| 1ek5 | NAD | UDP-glucose 4-epimerase | / | 0.656 | |
| 1w8d | NAP | 2,4-dienoyl-CoA reductase, mitochondrial | 1.3.1.34 | 0.656 | |
| 4dqu | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.656 | |
| 4twr | NAD | NAD binding site:NAD-dependent epimerase/dehydratase:UDP-glucose 4-epimerase | / | 0.656 | |
| 5b1y | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.656 | |
| 1dhr | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.655 | |
| 1eq2 | NAP | ADP-L-glycero-D-manno-heptose-6-epimerase | / | 0.655 | |
| 3ulk | NDP | Ketol-acid reductoisomerase (NADP(+)) | / | 0.655 | |
| 2hrb | NAP | Carbonyl reductase [NADPH] 3 | 1.1.1.184 | 0.654 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.654 | |
| 3wmx | NAD | NAD dependent epimerase/dehydratase | / | 0.654 | |
| 4qxm | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.654 | |
| 1t2a | NDP | GDP-mannose 4,6 dehydratase | 4.2.1.47 | 0.652 | |
| 3nt2 | NAD | Inositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase | 1.1.1.18 | 0.652 | |
| 1h50 | FMN | Pentaerythritol tetranitrate reductase | / | 0.651 | |
| 3aw9 | NAD | NAD-dependent epimerase/dehydratase | / | 0.651 |