sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Modes are compared using Grim.
For more information, please see the following publication:
Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2ztu | NAD | D(-)-3-hydroxybutyrate dehydrogenase |
| PDB ID | HET | Uniprot Name | EC Number | Binding Mode Similarity |
Align |
|---|---|---|---|---|---|
| 2ztu | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 1.109 | |
| 2ztv | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.967 | |
| 2q2v | NAD | Beta-D-hydroxybutyrate dehydrogenase | / | 0.905 | |
| 2ztm | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.903 | |
| 2dte | NAI | Glucose 1-dehydrogenase related protein | / | 0.870 | |
| 3w8e | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.861 | |
| 2d1y | NAD | Oxidoreductase, short-chain dehydrogenase/reductase family | / | 0.843 | |
| 3w8d | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.832 | |
| 3w8f | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.819 | |
| 3vdq | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.815 | |
| 2ztl | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.814 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.807 | |
| 2y99 | NAD | Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase | 1.3.1.56 | 0.805 | |
| 2q2q | NAD | Beta-D-hydroxybutyrate dehydrogenase | / | 0.796 | |
| 1h5q | NAP | NADP-dependent mannitol dehydrogenase | 1.1.1.138 | 0.795 | |
| 1bdb | NAD | Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase | / | 0.786 | |
| 3a28 | NAD | L-2,3-butanediol dehydrogenase | 1.1.1.76 | 0.786 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.786 | |
| 3nug | NAD | Pyridoxal 4-dehydrogenase | 1.1.1.107 | 0.785 | |
| 3p19 | NDP | Putative blue fluorescent protein | / | 0.785 | |
| 2zat | NAP | Dehydrogenase/reductase SDR family member 4 | 1.1.1.184 | 0.784 | |
| 3qrw | NDP | Putative ketoacyl reductase | 1.3.1 | 0.784 | |
| 5jsf | NAD | 17-beta-hydroxysteroid dehydrogenase 14 | 1.1.1 | 0.784 | |
| 1geg | NAD | Diacetyl reductase [(S)-acetoin forming] | 1.1.1.304 | 0.782 | |
| 1x7g | NAP | Putative ketoacyl reductase | 1.3.1 | 0.782 | |
| 4hp8 | NAP | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.782 | |
| 4is3 | NAD | 3alpha-hydroxy bile acid-CoA-ester 3-dehydrogenase 2 | 1.17.98.1 | 0.780 | |
| 1edo | NAP | 3-oxoacyl-[acyl-carrier-protein] reductase 1, chloroplastic | 1.1.1.100 | 0.779 | |
| 2ekp | NAD | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.779 | |
| 3ai3 | NDP | NADPH-sorbose reductase | / | 0.778 | |
| 4kwh | NAP | Reductase homolog | / | 0.776 | |
| 4dc0 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.775 | |
| 4rf2 | NAP | NADPH dependent R-specific alcohol dehydrogenase | / | 0.775 | |
| 1ipe | NDP | Tropinone reductase 2 | 1.1.1.236 | 0.774 | |
| 4dmm | NAP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.772 | |
| 3ak4 | NAD | NADH-dependent quinuclidinone reductase | / | 0.770 | |
| 3pgx | NAD | Uncharacterized NAD-dependent oxidoreductase MAP_4146 | / | 0.770 | |
| 1n5d | NDP | Carbonyl reductase [NADPH] 1 | / | 0.769 | |
| 2bd0 | NAP | Sepiapterin reductase | / | 0.769 | |
| 4yai | NAI | C alpha-dehydrogenase | / | 0.769 | |
| 2wdz | NAD | Galactitol dehydrogenase | / | 0.768 | |
| 1g1a | NAD | dTDP-glucose 4,6-dehydratase | / | 0.766 | |
| 3ai2 | NDP | NADPH-sorbose reductase | / | 0.762 | |
| 1ae1 | NAP | Tropinone reductase 1 | / | 0.760 | |
| 2wsb | NAD | Galactitol dehydrogenase | / | 0.760 | |
| 3o26 | NDP | Salutaridine reductase | / | 0.760 | |
| 5js6 | NAD | 17-beta-hydroxysteroid dehydrogenase 14 | 1.1.1 | 0.760 | |
| 5idw | NAP | Short-chain dehydrogenase/reductase SDR | / | 0.759 | |
| 3wds | NAD | NADH-dependent quinuclidinone reductase | / | 0.757 | |
| 4yag | NAI | C alpha-dehydrogenase | / | 0.757 | |
| 1pr9 | NAP | L-xylulose reductase | 1.1.1.10 | 0.756 | |
| 2gdz | NAD | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | 1.1.1.141 | 0.756 | |
| 4b79 | NAD | Probable short-chain dehydrogenase | / | 0.756 | |
| 4k6f | NAP | Putative Acetoacetyl-CoA reductase | / | 0.756 | |
| 1bxk | NAD | dTDP-glucose 4,6-dehydratase 2 | / | 0.755 | |
| 1g0n | NDP | Tetrahydroxynaphthalene reductase | 1.1.1.252 | 0.754 | |
| 2b4q | NAP | Rhamnolipids biosynthesis 3-oxoacyl-[acyl-carrier-protein] reductase | 1.1.1.100 | 0.754 | |
| 2rbe | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.754 | |
| 4dc1 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.754 | |
| 4hwk | NAP | Sepiapterin reductase | 1.1.1.153 | 0.754 | |
| 2dkn | NAI | 3-alpha-hydroxysteroid dehydrogenase | / | 0.752 | |
| 2p5y | NAD | UDP-glucose 4-epimerase | / | 0.752 | |
| 4u7w | NDP | MxaA | / | 0.752 | |
| 1oaa | NAP | Sepiapterin reductase | 1.1.1.153 | 0.751 | |
| 2c29 | NAP | Dihydroflavonol 4-reductase | / | 0.750 | |
| 4j7u | NAP | Sepiapterin reductase | 1.1.1.153 | 0.749 | |
| 1xse | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.748 | |
| 5jla | NAD | Putative short-chain dehydrogenase/reductase | / | 0.748 | |
| 2c59 | NAD | GDP-mannose 3,5-epimerase | 5.1.3.18 | 0.746 | |
| 3rj5 | NAD | Alcohol dehydrogenase | 1.1.1.1 | 0.746 | |
| 4o0l | NDP | NADPH-dependent 3-quinuclidinone reductase | / | 0.745 | |
| 3g49 | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.744 | |
| 1x7h | NDP | Putative ketoacyl reductase | 1.3.1 | 0.743 | |
| 1xg5 | NAP | Dehydrogenase/reductase SDR family member 11 | / | 0.743 | |
| 3tn7 | NJP | Short-chain alcohol dehydrogenase | / | 0.743 | |
| 4hxy | NDP | Plm1 | / | 0.743 | |
| 1e3s | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.741 | |
| 3d3w | NAP | L-xylulose reductase | 1.1.1.10 | 0.741 | |
| 4fw8 | NAI | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.741 | |
| 1sny | NAP | LD36273p | / | 0.740 | |
| 4iqg | NAP | Short-chain dehydrogenase/reductase SDR | / | 0.740 | |
| 2idz | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.739 | |
| 4bmv | NAP | Short-chain dehydrogenase | / | 0.739 | |
| 1zem | NAD | Xylitol dehydrogenase | / | 0.738 | |
| 2wyv | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.737 | |
| 3ehe | NAD | UDP-glucose 4-epimerase (GalE-1) | / | 0.734 | |
| 1gee | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.733 | |
| 3sj7 | NDP | 3-oxoacyl-(Acyl-carrier-protein) reductase, putative | / | 0.733 | |
| 2q1s | NAI | Putative nucleotide sugar epimerase/ dehydratase | / | 0.732 | |
| 3s55 | NAD | Putative short-chain dehydrogenase/reductase | / | 0.732 | |
| 4z3d | NDP | Carbonyl reductase [NADPH] 1 | 1.1.1.184 | 0.731 | |
| 3oew | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.730 | |
| 4fj0 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.730 | |
| 4j7x | NAP | Sepiapterin reductase | 1.1.1.153 | 0.730 | |
| 1w8d | NAP | 2,4-dienoyl-CoA reductase, mitochondrial | 1.3.1.34 | 0.729 | |
| 3geg | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.729 | |
| 3uce | NDP | Dehydrogenase | / | 0.729 | |
| 1cyd | NDP | Carbonyl reductase [NADPH] 2 | 1.1.1.184 | 0.728 | |
| 1u7t | TDT | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.728 | |
| 3ndr | NAD | Pyridoxal 4-dehydrogenase | 1.1.1.107 | 0.728 | |
| 3rj9 | NAD | Alcohol dehydrogenase | 1.1.1.1 | 0.727 | |
| 1e6w | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.726 | |
| 2jah | NDP | Clavaldehyde dehydrogenase | / | 0.726 | |
| 4nbt | NAD | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.726 | |
| 1rwb | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.725 | |
| 1gco | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.723 | |
| 2aqh | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.722 | |
| 3lu1 | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.722 | |
| 3ko8 | NAD | NAD-dependent epimerase/dehydratase | / | 0.721 | |
| 2aqi | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.720 | |
| 4gh5 | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.720 | |
| 5ig2 | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.720 | |
| 2hrb | NAP | Carbonyl reductase [NADPH] 3 | 1.1.1.184 | 0.719 | |
| 3bmo | NAP | Pteridine reductase | / | 0.717 | |
| 3iah | NAP | Putative oxoacyl-(Acyl carrier protein) reductase | / | 0.717 | |
| 4eue | NAI | Trans-2-enoyl-CoA reductase [NADH] | / | 0.717 | |
| 5cpb | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.717 | |
| 5jy1 | NAD | Putative short-chain dehydrogenase/reductase | / | 0.717 | |
| 5d2e | NAP | MlnE | / | 0.716 | |
| 2aq8 | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.715 | |
| 3of2 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.715 | |
| 3aut | NAI | Glucose 1-dehydrogenase 4 | 1.1.1.47 | 0.714 | |
| 2q1w | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.713 | |
| 2q1t | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.712 | |
| 4b8z | NAP | GDP-L-fucose synthase | 1.1.1.271 | 0.712 | |
| 4wec | NAD | Short chain dehydrogenase | / | 0.712 | |
| 3r3s | NAD | Putative oxidoreductase | / | 0.711 | |
| 1e3w | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.710 | |
| 3gy0 | NAP | NAD(P)-dependent oxidoreductase | / | 0.710 | |
| 3sju | NDP | Keto reductase | / | 0.710 | |
| 4dqu | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.710 | |
| 4fc7 | NAP | Peroxisomal 2,4-dienoyl-CoA reductase | 1.3.1.34 | 0.710 | |
| 5jyd | NAD | Short chain dehydrogenase | / | 0.710 | |
| 2b35 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.709 | |
| 3mje | NDP | AmphB | / | 0.709 | |
| 3o03 | NAP | Dehydrogenase with different specificities (Related to short-chain alcohol dehydrogenase) | / | 0.709 | |
| 3rku | NAP | NADP-dependent 3-hydroxy acid dehydrogenase | / | 0.709 | |
| 4oxy | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.709 | |
| 2ieb | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.708 | |
| 2pr2 | DG1 | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.708 | |
| 4fj1 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.707 | |
| 1eny | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.706 | |
| 1nfr | NAD | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.706 | |
| 1v35 | NAI | Enoyl-ACP reductase | / | 0.706 | |
| 1iy8 | NAD | Levodione reductase | / | 0.705 | |
| 1xkq | NDP | Uncharacterized protein | / | 0.705 | |
| 3aw9 | NAD | NAD-dependent epimerase/dehydratase | / | 0.705 | |
| 3icp | NAD | NAD-dependent epimerase/dehydratase | / | 0.705 | |
| 2nnl | NAP | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.704 | |
| 4clo | NAP | Pteridine reductase | / | 0.704 | |
| 4lis | NAD | UDP-glucose 4-epimerase (Eurofung) | / | 0.704 | |
| 4m87 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.704 | |
| 4pvd | NDP | NADPH-dependent methylglyoxal reductase GRE2 | / | 0.704 | |
| 2ag5 | NAD | 3-hydroxybutyrate dehydrogenase type 2 | / | 0.703 | |
| 2nv6 | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.703 | |
| 3bhi | NAP | Carbonyl reductase [NADPH] 1 | 1.1.1.184 | 0.703 | |
| 2aqk | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.702 | |
| 2o23 | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.702 | |
| 1g6k | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.701 | |
| 3tsc | NAD | Uncharacterized protein | / | 0.701 | |
| 4dre | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.701 | |
| 1b2l | NDC | Alcohol dehydrogenase | 1.1.1.1 | 0.699 | |
| 1vl8 | NAP | Oxidoreductase, short chain dehydrogenase/reductase family | / | 0.699 | |
| 3tox | NAP | Putative oxidoreductase | / | 0.699 | |
| 4dti | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.699 | |
| 1b15 | NAE | Alcohol dehydrogenase | 1.1.1.1 | 0.697 | |
| 1fdu | NAP | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.697 | |
| 2ie0 | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.697 | |
| 3oey | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.696 | |
| 1w4z | NAP | Putative ketoacyl reductase | 1.3.1 | 0.695 | |
| 1i2b | NAD | UDP-sulfoquinovose synthase, chloroplastic | 3.13.1.1 | 0.693 | |
| 4fj2 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.693 | |
| 3qwf | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.692 | |
| 2z1m | NDP | GDP-mannose 4,6-dehydratase | / | 0.691 | |
| 1b16 | NAQ | Alcohol dehydrogenase | 1.1.1.1 | 0.689 | |
| 1vrw | NAI | Enoyl-ACP reductase | / | 0.689 | |
| 2ntj | P1H | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.689 | |
| 4hbg | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | 1.1.1.100 | 0.689 | |
| 4qed | NAP | ElxO | / | 0.689 | |
| 4fn4 | NAD | Short chain dehydrogenase | / | 0.688 | |
| 2hun | NAD | 336aa long hypothetical dTDP-glucose 4,6-dehydratase | / | 0.687 | |
| 3uic | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.686 | |
| 3zu2 | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.686 | |
| 3ijr | NAD | Oxidoreductase, short chain dehydrogenase/reductase family | / | 0.685 | |
| 4trn | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.685 | |
| 2pzj | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.684 | |
| 2yw9 | NAP | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.684 | |
| 3uxy | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.684 | |
| 1nff | NAD | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.683 | |
| 1orr | NAD | CDP-paratose 2-epimerase | / | 0.683 | |
| 1sby | NAD | Alcohol dehydrogenase | 1.1.1.1 | 0.683 | |
| 1mg5 | NAI | Alcohol dehydrogenase | 1.1.1.1 | 0.682 | |
| 2bgl | NAJ | Secoisolariciresinol dehydrogenase | 1.1.1.331 | 0.681 | |
| 2ntv | P1H | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.681 | |
| 2q1u | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.680 | |
| 2yy7 | NAD | L-threonine dehydrogenase | / | 0.679 | |
| 1w73 | NAP | 2,4-dienoyl-CoA reductase, mitochondrial | 1.3.1.34 | 0.678 | |
| 2bgm | NAJ | Secoisolariciresinol dehydrogenase | 1.1.1.331 | 0.678 | |
| 3l77 | NJP | Short-chain alcohol dehydrogenase | / | 0.678 | |
| 4bqp | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.676 | |
| 1qyv | NAP | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.675 | |
| 4bgi | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.674 | |
| 4qec | NAP | ElxO | / | 0.674 | |
| 2yut | NAP | Putative short-chain oxidoreductase | / | 0.673 | |
| 3f1k | NAP | Uncharacterized oxidoreductase YciK | 1 | 0.673 | |
| 2h9i | EAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.672 | |
| 3ru9 | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.672 | |
| 3rud | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.672 | |
| 3ruf | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.672 | |
| 4nbu | NAI | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.672 | |
| 4egb | NAD | dTDP-glucose 4,6-dehydratase | / | 0.671 | |
| 5bt9 | NAP | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.671 | |
| 2nq8 | ZID | Enoyl-ACP reductase | / | 0.670 | |
| 4bii | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.670 | |
| 4n5n | NAP | Acetoacetyl-CoA reductase | 1.1.1.36 | 0.670 | |
| 4qxm | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.670 | |
| 4ihi | NAD | Probable pyrroline-5-carboxylate dehydrogenase RocA | / | 0.669 | |
| 1enz | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.668 | |
| 2p9g | NAI | D-3-phosphoglycerate dehydrogenase | 1.1.1.95 | 0.668 | |
| 3h4v | NAP | Pteridine reductase 1 | 1.5.1.33 | 0.668 | |
| 1b14 | NAD | Alcohol dehydrogenase | 1.1.1.1 | 0.667 | |
| 2x6t | NAP | ADP-L-glycero-D-manno-heptose-6-epimerase | / | 0.667 | |
| 2b37 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.665 | |
| 2bfo | NDP | Pteridine reductase 1 | 1.5.1.33 | 0.665 | |
| 3rua | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.665 | |
| 5lc1 | NAD | L-threonine 3-dehydrogenase | / | 0.663 | |
| 1rkx | NAD | CDP-D-glucose-4,6-dehydratase | / | 0.662 | |
| 1zid | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.662 | |
| 3orf | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.662 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.661 | |
| 1kvr | NAD | UDP-glucose 4-epimerase | 5.1.3.2 | 0.661 | |
| 3rue | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.661 | |
| 2ydx | NAP | Methionine adenosyltransferase 2 subunit beta | / | 0.659 | |
| 1nah | NAD | UDP-glucose 4-epimerase | 5.1.3.2 | 0.658 | |
| 3pvz | NAD | UDP-N-acetylglucosamine 4,6-dehydratase | / | 0.658 | |
| 3u4c | NDP | NADPH-dependent reductase BacG | / | 0.658 | |
| 1lsj | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.657 | |
| 3ruc | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.657 | |
| 2p5u | NAD | UDP-glucose 4-epimerase | / | 0.656 | |
| 1fk8 | NAD | 3-alpha-hydroxysteroid dehydrogenase/carbonyl reductase | 1.1.1.50 | 0.655 | |
| 1u7t | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.655 | |
| 4o1m | NAD | Enoyl-acyl carrier reductase | / | 0.655 | |
| 3rhr | NDP | Cytosolic 10-formyltetrahydrofolate dehydrogenase | 1.5.1.6 | 0.653 | |
| 4bms | NAP | Alclohol dehydrogenase/short-chain dehydrogenase | / | 0.653 | |
| 1ek5 | NAD | UDP-glucose 4-epimerase | / | 0.652 | |
| 4nbw | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.652 | |
| 4bkq | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.651 | |
| 4cql | NAD | Estradiol 17-beta-dehydrogenase 8 | 1.1.1.62 | 0.651 | |
| 2p9c | NAI | D-3-phosphoglycerate dehydrogenase | 1.1.1.95 | 0.650 | |
| 3wmx | NAD | NAD dependent epimerase/dehydratase | / | 0.650 |