sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 5ioq | DUR | Flavin-dependent thymidylate synthase | 2.1.1.148 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 5ioq | DUR | Flavin-dependent thymidylate synthase | 2.1.1.148 | 1.000 | |
| 5iot | UMP | Flavin-dependent thymidylate synthase | 2.1.1.148 | 0.512 | |
| 2oap | ANP | Type II secretion system protein (GspE-2) | / | 0.490 | |
| 4qms | 1N1 | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.490 | |
| 4mxx | DB8 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.489 | |
| 2itw | ITQ | Epidermal growth factor receptor | 2.7.10.1 | 0.486 | |
| 1i59 | ADP | Chemotaxis protein CheA | 2.7.13.3 | 0.483 | |
| 2zaz | GK1 | Mitogen-activated protein kinase 14 | / | 0.483 | |
| 2qo9 | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.482 | |
| 3vjo | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.481 | |
| 3kc0 | 2T5 | Fructose-1,6-bisphosphatase 1 | 3.1.3.11 | 0.479 | |
| 2y6o | 1N1 | Ephrin type-A receptor 4 | 2.7.10.1 | 0.476 | |
| 1cf2 | NAP | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.475 | |
| 1cqp | 803 | Integrin alpha-L | / | 0.474 | |
| 1zth | ADP | RIO-type serine/threonine-protein kinase Rio1 | 2.7.11.1 | 0.474 | |
| 2itu | ITQ | Epidermal growth factor receptor | 2.7.10.1 | 0.474 | |
| 2rlc | CHD | Choloylglycine hydrolase | 3.5.1.24 | 0.474 | |
| 2zyb | KSL | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.474 | |
| 2vwx | 7X4 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.473 | |
| 2xck | MH4 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.473 | |
| 3ac5 | KZM | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.473 | |
| 1m17 | AQ4 | Epidermal growth factor receptor | 2.7.10.1 | 0.472 | |
| 2ddo | ATP | Pyridoxine/pyridoxal/pyridoxamine kinase | / | 0.470 | |
| 2zm4 | KSM | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.470 | |
| 3apw | DP0 | Alpha-1-acid glycoprotein 2 | / | 0.470 | |
| 4hjo | AQ4 | Epidermal growth factor receptor | 2.7.10.1 | 0.470 | |
| 1il0 | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.469 | |
| 2z4s | ADP | Chromosomal replication initiator protein DnaA | / | 0.469 | |
| 2zm1 | KSF | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.469 | |
| 2pe1 | 517 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.468 | |
| 4eqc | XR1 | Serine/threonine-protein kinase PAK 1 | 2.7.11.1 | 0.468 | |
| 4i23 | 1C9 | Epidermal growth factor receptor | 2.7.10.1 | 0.468 | |
| 2ohv | NHL | Glutamate racemase | / | 0.467 | |
| 4mxo | DB8 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.467 | |
| 2itv | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.466 | |
| 3p82 | FMN | Pentaerythritol tetranitrate reductase | / | 0.466 | |
| 3p0j | TYE | Putative tyrosyl-tRNA synthetase | / | 0.465 | |
| 4ie0 | PD2 | Alpha-ketoglutarate-dependent dioxygenase FTO | / | 0.465 | |
| 1xnj | ADP | Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1 | 2.7.1.25 | 0.464 | |
| 1z5a | ADP | Type 2 DNA topoisomerase 6 subunit B | / | 0.464 | |
| 3s1d | ZIR | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.464 | |
| 1di9 | MSQ | Mitogen-activated protein kinase 14 | / | 0.463 | |
| 2nnq | T4B | Fatty acid-binding protein, adipocyte | / | 0.463 | |
| 2q46 | NAP | Uncharacterized protein At5g02240 | / | 0.463 | |
| 3h06 | VBP | Glutamate receptor 2 | / | 0.463 | |
| 3op5 | REB | Serine/threonine-protein kinase VRK1 | 2.7.11.1 | 0.463 | |
| 4die | C5P | Cytidylate kinase | / | 0.463 | |
| 4tmc | FMN | Old yellow enzyme | / | 0.463 | |
| 1p9w | ANP | Type II secretion system protein E | / | 0.462 | |
| 2itx | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.462 | |
| 3mvm | 39P | Mitogen-activated protein kinase 14 | / | 0.462 | |
| 3q5d | GDP | Atlastin-1 | 3.6.5 | 0.462 | |
| 4fkg | 4CK | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.462 | |
| 2itq | ITQ | Epidermal growth factor receptor | 2.7.10.1 | 0.461 | |
| 2vwq | NAP | Glucose 1-dehydrogenase | / | 0.461 | |
| 4hia | FMN | LOV protein | / | 0.461 | |
| 1fpq | SAM | Isoliquiritigenin 2'-O-methyltransferase | / | 0.460 | |
| 1m75 | CAA | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.460 | |
| 2of4 | 979 | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.460 | |
| 2olr | ATP | Phosphoenolpyruvate carboxykinase (ATP) | / | 0.460 | |
| 2qg4 | NAD | UDP-glucose 6-dehydrogenase | 1.1.1.22 | 0.460 | |
| 2v51 | LAB | Actin, alpha skeletal muscle | / | 0.460 | |
| 3d2r | ADP | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial | 2.7.11.2 | 0.460 | |
| 3kji | ADP | CO dehydrogenase/acetyl-CoA synthase complex, accessory protein CooC | / | 0.460 | |
| 4dpu | AGS | Mevalonate diphosphate decarboxylase | / | 0.460 | |
| 4h1m | 0YJ | Protein-tyrosine kinase 2-beta | 2.7.10.2 | 0.460 | |
| 1nzf | UPG | DNA beta-glucosyltransferase | / | 0.459 | |
| 1szm | BI4 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.459 | |
| 1z2n | ADP | Inositol-tetrakisphosphate 1-kinase | 2.7.1.134 | 0.459 | |
| 2rgh | FAD | Alpha-Glycerophosphate Oxidase | / | 0.459 | |
| 2zva | 1N1 | Tyrosine-protein kinase Lyn | 2.7.10.2 | 0.459 | |
| 4dan | 2FA | Purine nucleoside phosphorylase DeoD-type | 2.4.2.1 | 0.459 | |
| 4jrv | KJV | Epidermal growth factor receptor | 2.7.10.1 | 0.459 | |
| 1lol | XMP | Orotidine 5'-phosphate decarboxylase | 4.1.1.23 | 0.458 | |
| 1vi2 | NAD | Quinate/shikimate dehydrogenase | / | 0.458 | |
| 2nr4 | FMN | Conserved protein | / | 0.458 | |
| 2tps | TPS | Thiamine-phosphate synthase | / | 0.458 | |
| 3ac2 | KSE | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.458 | |
| 3dyn | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.458 | |
| 3gbu | ATP | Uncharacterized sugar kinase PH1459 | 2.7.1 | 0.458 | |
| 3t50 | FMN | Blue-light-activated histidine kinase | 2.7.13.3 | 0.458 | |
| 4gyz | D5M | Tyrosyl-DNA phosphodiesterase 2 | 3.1.4 | 0.458 | |
| 1g9c | BAB | Botulinum neurotoxin type B | 3.4.24.69 | 0.457 | |
| 1rfu | ADP | Pyridoxal kinase | 2.7.1.35 | 0.457 | |
| 3kr4 | BES | M17 leucyl aminopeptidase | / | 0.457 | |
| 4c02 | TAK | Activin receptor type-1 | 2.7.11.30 | 0.457 | |
| 4z87 | 5GP | Inosine-5'-monophosphate dehydrogenase | / | 0.457 | |
| 1eio | GCH | Gastrotropin | / | 0.456 | |
| 1lhw | ESM | Sex hormone-binding globulin | / | 0.456 | |
| 1wkh | PPE | [LysW]-aminoadipate semialdehyde transaminase | / | 0.456 | |
| 2gr0 | FAD | Ferredoxin reductase | / | 0.456 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.456 | |
| 3cgc | COA | Coenzyme A disulfide reductase | / | 0.456 | |
| 3ns2 | PYV | Abscisic acid receptor PYL2 | / | 0.456 | |
| 4jlo | ADP | Adenylate kinase | / | 0.456 | |
| 4tv3 | ML9 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform | / | 0.456 | |
| 1x2h | LPA | Lipoate-protein ligase A | 6.3.1.20 | 0.455 | |
| 3kr5 | BEY | M17 leucyl aminopeptidase | / | 0.455 | |
| 3pcf | FHB | Protocatechuate 3,4-dioxygenase beta chain | 1.13.11.3 | 0.455 | |
| 2chz | 093 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.454 | |
| 2ds1 | 1CD | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.454 | |
| 2f3r | G5P | Guanylate kinase | 2.7.4.8 | 0.454 | |
| 2j9g | ADP | Biotin carboxylase | 6.3.4.14 | 0.454 | |
| 2rki | TT1 | Gag-Pol polyprotein | 2.7.7.49 | 0.454 | |
| 2ylr | NAP | Phenylacetone monooxygenase | 1.14.13.92 | 0.454 | |
| 3qs8 | 17D | Anthranilate phosphoribosyltransferase | / | 0.454 | |
| 4m11 | MXM | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.454 | |
| 1vyr | FMN | Pentaerythritol tetranitrate reductase | / | 0.453 | |
| 1y57 | MPZ | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.453 | |
| 2py7 | ATP | Phosphoenolpyruvate carboxykinase (ATP) | / | 0.453 | |
| 2r2n | KYN | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.453 | |
| 2ym5 | YM5 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.453 | |
| 3a14 | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | / | 0.453 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.453 | |
| 3sqw | ANP | ATP-dependent RNA helicase MSS116, mitochondrial | 3.6.4.13 | 0.453 | |
| 4eft | EFT | Heat shock protein HSP 90-alpha | / | 0.453 | |
| 1gii | 1PU | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.452 | |
| 1h6v | NDP | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.452 | |
| 3au8 | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic | 1.1.1.267 | 0.452 | |
| 3b2e | ADP | ATPase GET3 | / | 0.452 | |
| 3lfm | 3DT | Alpha-ketoglutarate-dependent dioxygenase FTO | / | 0.452 | |
| 3mpt | 1GK | Mitogen-activated protein kinase 14 | / | 0.452 | |
| 4dpy | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.452 | |
| 4fxy | 0W2 | Neurolysin, mitochondrial | 3.4.24.16 | 0.452 | |
| 4kiq | 1RA | Mitogen-activated protein kinase 14 | / | 0.452 | |
| 4y9q | C2E | Uncharacterized protein | / | 0.452 | |
| 4z17 | PEP | Enolase | / | 0.452 | |
| 5kgp | ACO | Predicted acetyltransferase | / | 0.452 | |
| 1f3p | NAD | Ferredoxin reductase | / | 0.451 | |
| 1fp6 | ADP | Nitrogenase iron protein 1 | 1.18.6.1 | 0.451 | |
| 2dbz | NAP | Glyoxylate reductase | 1.1.1.26 | 0.451 | |
| 2of2 | 547 | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.451 | |
| 3orm | AGS | Serine/threonine protein kinase | / | 0.451 | |
| 4ct1 | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.451 | |
| 4g95 | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 1i58 | ADP | Chemotaxis protein CheA | 2.7.13.3 | 0.450 | |
| 1i5c | ADP | Chemotaxis protein CheA | 2.7.13.3 | 0.450 | |
| 1m8k | NAD | Nicotinamide-nucleotide adenylyltransferase | 2.7.7.1 | 0.450 | |
| 2cy0 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.450 | |
| 2xf3 | J01 | Uncharacterized protein | / | 0.450 | |
| 3otw | COA | Phosphopantetheine adenylyltransferase | / | 0.450 | |
| 3r1r | ATP | Ribonucleoside-diphosphate reductase 1 subunit alpha | 1.17.4.1 | 0.450 | |
| 4bf2 | STU | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.450 | |
| 4c3f | 7KW | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.450 | |
| 4dre | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.450 | |
| 4m55 | NAD | UDP-glucuronic acid decarboxylase 1 | 4.1.1.35 | 0.450 | |
| 4qmx | H8H | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.450 | |
| 4rqv | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.450 | |
| 4uyf | 73B | Bromodomain-containing protein 2 | / | 0.450 | |
| 4xx9 | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.450 | |
| 1dxy | NAD | D-2-hydroxyisocaproate dehydrogenase | 1.1.1 | 0.449 | |
| 1e90 | MYC | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.449 | |
| 1tqf | 32P | Beta-secretase 1 | 3.4.23.46 | 0.449 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.449 | |
| 2ww4 | ADP | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | 2.7.1.148 | 0.449 | |
| 3cgd | FAD | Coenzyme A disulfide reductase | / | 0.449 | |
| 3fr5 | I4A | Fatty acid-binding protein, adipocyte | / | 0.449 | |
| 4ejm | NAP | Putative zinc-binding dehydrogenase | / | 0.449 | |
| 4jq7 | KJQ | Epidermal growth factor receptor | 2.7.10.1 | 0.449 | |
| 4k5s | PM0 | Oxygenase | / | 0.449 | |
| 4l42 | 5FI | Ribosomal protein S6 kinase beta-1 | 2.7.11.1 | 0.449 | |
| 1bwl | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.448 | |
| 1t2c | NAI | L-lactate dehydrogenase | 1.1.1.27 | 0.448 | |
| 2bal | PQA | Mitogen-activated protein kinase 14 | / | 0.448 | |
| 2bdj | HET | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.448 | |
| 2itp | AEE | Epidermal growth factor receptor | 2.7.10.1 | 0.448 | |
| 2rhr | EMO | Putative ketoacyl reductase | 1.3.1 | 0.448 | |
| 2y1o | T26 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.448 | |
| 3ac3 | KSH | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.448 | |
| 3ag9 | A02 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.448 | |
| 3zw3 | ZW3 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.448 | |
| 4ewn | 0VR | Imidazole glycerol phosphate synthase subunit HisF | 4.1.3 | 0.448 | |
| 1bxo | PP7 | Penicillopepsin-1 | 3.4.23.20 | 0.447 | |
| 1dz8 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.447 | |
| 1i58 | ACP | Chemotaxis protein CheA | 2.7.13.3 | 0.447 | |
| 1qpe | PP2 | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.447 | |
| 2d8a | NAD | L-threonine 3-dehydrogenase | / | 0.447 | |
| 2o23 | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.447 | |
| 2rdn | 1PL | 1-deoxypentalenic acid 11-beta-hydroxylase | 1.14.11.35 | 0.447 | |
| 2w9h | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 2y3s | TIR | TamL | / | 0.447 | |
| 3c0i | 3AM | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.447 | |
| 3fr8 | NDP | Ketol-acid reductoisomerase, chloroplastic | 1.1.1.86 | 0.447 | |
| 3tnl | NAD | Shikimate dehydrogenase (NADP(+)) | / | 0.447 | |
| 4m69 | ANP | Receptor-interacting serine/threonine-protein kinase 3 | 2.7.11.1 | 0.447 | |
| 4xli | 1N1 | Abelson tyrosine-protein kinase 2 | 2.7.10.2 | 0.447 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.446 | |
| 2cmo | M1L | Glutamate receptor 2 | / | 0.446 | |
| 2ojg | 19A | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.446 | |
| 2ym3 | YM3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.446 | |
| 3c50 | ADP | Rhodopsin kinase | / | 0.446 | |
| 3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.446 | |
| 3nta | COA | FAD-dependent pyridine nucleotide-disulphide oxidoreductase | / | 0.446 | |
| 3ort | AGS | Serine/threonine protein kinase | / | 0.446 | |
| 4fd2 | ADP | Chaperone protein ClpB | / | 0.446 | |
| 4otp | ADP | Serine/threonine-protein kinase RIO1 | 2.7.11.1 | 0.446 | |
| 4r2l | ATP | Universal stress protein F | / | 0.446 | |
| 4wud | ANP | DNA gyrase subunit B | / | 0.446 | |
| 5ein | NAP | [LysW]-L-2-aminoadipate 6-phosphate reductase | / | 0.446 | |
| 1diu | BDM | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 1j39 | UPG | DNA beta-glucosyltransferase | / | 0.445 | |
| 1pl8 | NAD | Sorbitol dehydrogenase | 1.1.1.14 | 0.445 | |
| 1rby | KEU | Trifunctional purine biosynthetic protein adenosine-3 | 2.1.2.2 | 0.445 | |
| 2b53 | D23 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.445 | |
| 2bri | ANP | Uridylate kinase | 2.7.4.22 | 0.445 | |
| 2l84 | J28 | CREB-binding protein | / | 0.445 | |
| 2uyy | NA7 | Putative oxidoreductase GLYR1 | 1 | 0.445 | |
| 3ac1 | KZI | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.445 | |
| 3fwy | ADP | Light-independent protochlorophyllide reductase iron-sulfur ATP-binding protein | / | 0.445 | |
| 3nl6 | TPS | Uncharacterized protein | / | 0.445 | |
| 3ntd | COA | FAD-dependent pyridine nucleotide-disulphide oxidoreductase | / | 0.445 | |
| 3svj | 4LI | Peptide deformylase | / | 0.445 | |
| 4d81 | ADP | AAA ATPase, central domain protein | / | 0.445 | |
| 4fv7 | E94 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.445 | |
| 4hjf | C2E | GGDEF family protein | / | 0.445 | |
| 4jql | VJ6 | Heat shock protein HSP 90-alpha | / | 0.445 | |
| 1a8p | FAD | Ferredoxin--NADP reductase | / | 0.444 | |
| 1i5a | ACP | Chemotaxis protein CheA | 2.7.13.3 | 0.444 | |
| 1mqw | ADV | MutT/nudix family protein | / | 0.444 | |
| 1zar | ADP | RIO-type serine/threonine-protein kinase Rio2 | 2.7.11.1 | 0.444 | |
| 2a7r | 5GP | GMP reductase 2 | / | 0.444 | |
| 2bjf | DXC | Choloylglycine hydrolase | 3.5.1.24 | 0.444 | |
| 2bre | KJ2 | ATP-dependent molecular chaperone HSP82 | / | 0.444 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.444 | |
| 2qtv | GNP | Small COPII coat GTPase SAR1 | 3.6.5 | 0.444 | |
| 2ydx | STL | Methionine adenosyltransferase 2 subunit beta | / | 0.444 | |
| 3a4v | NAD | NDP-sugar epimerase | / | 0.444 | |
| 3evb | SAH | Genome polyprotein | 2.1.1.56 | 0.444 | |
| 3m2u | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.444 | |
| 3uic | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.444 | |
| 4e90 | 7RG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.444 | |
| 4lht | CNL | 1,8-cineole 2-endo-monooxygenase | 1.14.13.156 | 0.444 | |
| 4lj9 | ACP | Chaperone protein ClpB | / | 0.444 | |
| 4xhg | ADP | Uncharacterized protein | / | 0.444 | |
| 5f0a | 1FB | cGMP-dependent protein kinase, putative | / | 0.444 | |
| 1f20 | NAP | Nitric oxide synthase, brain | 1.14.13.39 | 0.443 | |
| 1h1w | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.443 | |
| 1txt | CAA | HMG-CoA synthase | / | 0.443 | |
| 2ay3 | MPP | Aromatic-amino-acid aminotransferase | 2.6.1.57 | 0.443 | |
| 2b9y | FAD | Putative aminooxidase | / | 0.443 | |
| 2qfx | NDP | Isocitrate dehydrogenase [NADP], mitochondrial | 1.1.1.42 | 0.443 | |
| 3mtf | A3F | Activin receptor type-1 | 2.7.11.30 | 0.443 | |
| 3opx | U5P | Suppressor of disruption of TFIIS | / | 0.443 | |
| 3t8w | DGZ | M17 leucyl aminopeptidase | / | 0.443 | |
| 3td7 | FAD | Probable FAD-linked sulfhydryl oxidase R596 | 1.8.3.2 | 0.443 | |
| 3vs6 | VSH | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.443 | |
| 3w8r | ACP | Uridine kinase | / | 0.443 | |
| 4du8 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.443 | |
| 4ezj | 0SC | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.443 | |
| 4hbm | 0Y7 | E3 ubiquitin-protein ligase Mdm2 | 6.3.2 | 0.443 | |
| 4wq5 | ATP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.443 | |
| 1dj3 | GDP | Adenylosuccinate synthetase, chloroplastic | / | 0.442 | |
| 1g4t | FTP | Thiamine-phosphate synthase | / | 0.442 | |
| 1jm6 | ADP | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial | 2.7.11.2 | 0.442 | |
| 1mf0 | GDP | Adenylosuccinate synthetase isozyme 1 | / | 0.442 | |
| 1tou | B1V | Fatty acid-binding protein, adipocyte | / | 0.442 | |
| 1z5c | ADP | Type 2 DNA topoisomerase 6 subunit B | / | 0.442 | |
| 1zp9 | ATP | RIO-type serine/threonine-protein kinase Rio1 | 2.7.11.1 | 0.442 | |
| 2ch6 | ADP | N-acetyl-D-glucosamine kinase | 2.7.1.59 | 0.442 | |
| 2p4i | MR9 | Angiopoietin-1 receptor | 2.7.10.1 | 0.442 | |
| 2qdx | FAD | Ferredoxin--NADP+ reductase | / | 0.442 | |
| 2rh9 | IGP | Tryptophan synthase alpha chain | / | 0.442 | |
| 2xyu | Q9G | Ephrin type-A receptor 4 | 2.7.10.1 | 0.442 | |
| 3acj | KSS | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.442 | |
| 3ahi | HTL | Probable phosphoketolase | / | 0.442 | |
| 3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.442 | |
| 3p67 | FMN | Pentaerythritol tetranitrate reductase | / | 0.442 | |
| 4bva | T3 | Ketimine reductase mu-crystallin | 1.5.1.25 | 0.442 | |
| 4g2j | 0WF | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.442 | |
| 4jrn | ANP | Rhoptry kinase family protein | / | 0.442 | |
| 4lg5 | A1O | Abscisic acid receptor PYL2 | / | 0.442 | |
| 5bsg | NAP | Pyrroline-5-carboxylate reductase | / | 0.442 | |
| 5eg3 | ACP | Fibroblast growth factor receptor 2 | / | 0.442 | |
| 1bxq | PP8 | Penicillopepsin-1 | 3.4.23.20 | 0.441 | |
| 1sn5 | T3 | Transthyretin | / | 0.441 | |
| 2acx | ANP | G protein-coupled receptor kinase 6 | 2.7.11.16 | 0.441 | |
| 2bdf | 24A | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.441 | |
| 2brb | PFQ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.441 | |
| 2hma | SAM | tRNA-specific 2-thiouridylase MnmA | / | 0.441 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.441 | |
| 2iyf | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.441 | |
| 2wns | OMP | Uridine 5'-monophosphate synthase | 2.4.2.10 | 0.441 | |
| 2xjx | XJX | Heat shock protein HSP 90-alpha | / | 0.441 | |
| 3b2s | B2S | Trichothecene 3-O-acetyltransferase | / | 0.441 | |
| 3m2v | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.441 | |
| 3nyr | MLC | Putative fatty acid synthase | / | 0.441 | |
| 3ocg | OCG | Mitogen-activated protein kinase 14 | / | 0.441 | |
| 3p8j | FMN | Pentaerythritol tetranitrate reductase | / | 0.441 | |
| 3pj8 | 404 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.441 | |
| 3w0p | ADP | Hygromycin-B 4-O-kinase | 2.7.1.163 | 0.441 | |
| 4an4 | DUD | Putative glycosyl transferase | / | 0.441 | |
| 4fyh | TR5 | 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 | / | 0.441 | |
| 4hj6 | FMN | LOV protein | / | 0.441 | |
| 4ie6 | UN9 | Alpha-ketoglutarate-dependent dioxygenase FTO | / | 0.441 | |
| 4nbw | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.441 | |
| 5ar4 | SB2 | Receptor-interacting serine/threonine-protein kinase 2 | 2.7.11.1 | 0.441 | |
| 1fmj | RTL | Retinol dehydratase | / | 0.440 | |
| 1hku | NAD | C-terminal-binding protein 1 | 1.1.1 | 0.440 | |
| 1joa | FAD | NADH peroxidase | 1.11.1.1 | 0.440 | |
| 1wvg | APR | CDP-glucose 4,6-dehydratase | 4.2.1.45 | 0.440 | |
| 2bue | COA | AAC(6')-Ib | / | 0.440 | |
| 2d1y | NAD | Oxidoreductase, short-chain dehydrogenase/reductase family | / | 0.440 | |
| 2i5b | ADP | Pyridoxine kinase | / | 0.440 | |
| 2oci | TYC | Valacyclovir hydrolase | 3.1 | 0.440 | |
| 2rkv | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.440 | |
| 2xka | GSP | Cell division protein FtsZ | / | 0.440 | |
| 3dv3 | MEK | Dual specificity mitogen-activated protein kinase kinase 1 | 2.7.12.2 | 0.440 | |
| 3el8 | PD5 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.440 | |
| 3f8k | COA | Uncharacterized protein | / | 0.440 | |
| 3kh5 | ADP | Uncharacterized protein MJ1225 | / | 0.440 | |
| 3oaf | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 3r6c | 17N | Anthranilate phosphoribosyltransferase | / | 0.440 | |
| 3tdw | GDP | Gentamicin resistance protein | / | 0.440 | |
| 3ub5 | ATP | Actin, cytoplasmic 1 | / | 0.440 | |
| 4c57 | FEF | Cyclin-G-associated kinase | 2.7.11.1 | 0.440 | |
| 4fhk | 0U0 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.440 | |
| 4gap | FAD | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.440 | |
| 4i6g | FAD | Cryptochrome-2 | / | 0.440 | |
| 4zju | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.440 |