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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3refGDPRho family GTPase

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
3refGDPRho family GTPase/1.000
1culGSPGuanine nucleotide-binding protein G(s) subunit alpha isoforms short/0.529
1mh1GNPRas-related C3 botulinum toxin substrate 1/0.518
3vhxGTPADP-ribosylation factor 6/0.518
4e03ADPPlasmid partitioning protein ParF/0.508
2p2lGDPRas-related C3 botulinum toxin substrate 1/0.506
1g4tFTPThiamine-phosphate synthase/0.505
4panGDPGuanine nucleotide-binding protein G(i) subunit alpha-1/0.505
1wdtGTPElongation factor G (EF-G-2)/0.503
3pcrGTPADP-ribosylation factor 6/0.503
3umsGDPGuanine nucleotide-binding protein G(i) subunit alpha-1/0.503
4fkv61KCyclin-dependent kinase 22.7.11.220.503
2q3fGNPRas-related GTP-binding protein D/0.502
1aztGSPGuanine nucleotide-binding protein G(s) subunit alpha isoforms short/0.501
4fidGDPG protein alpha subunit, putative/0.501
4hdqGNPRas-related protein Rap-1b/0.501
2vtoLZ8Cyclin-dependent kinase 22.7.11.220.500
1giaGSPGuanine nucleotide-binding protein G(i) subunit alpha-1/0.499
1gilGSPGuanine nucleotide-binding protein G(i) subunit alpha-1/0.499
5di3GNPADP-ribosylation factor-like protein 3/0.499
4eutBX7Serine/threonine-protein kinase TBK12.7.11.10.496
1e79ATPATP synthase subunit alpha, mitochondrial/0.495
1e79ATPATP synthase subunit beta, mitochondrial3.6.3.140.495
3r7wGNPGTP-binding protein GTR2/0.495
4dvgGSPRho family GTPase/0.495
1y3aGDPGuanine nucleotide-binding protein G(i) subunit alpha-1/0.489
3c16GSPGuanine nucleotide-binding protein G(s) subunit alpha isoforms short/0.489
4a4vYFDPeroxisome proliferator-activated receptor gamma/0.489
4e4qRRHPeroxisome proliferator-activated receptor gamma/0.488
4jazSTLPeroxisome proliferator-activated receptor gamma/0.488
3zonIK1Non-receptor tyrosine-protein kinase TYK22.7.10.20.485
1ky2GNPGTP-binding protein YPT7/0.484
4fvqATPTyrosine-protein kinase JAK2/0.483
4echFADPolyamine oxidase FMS1/0.482
4gzmGSPRas-related C3 botulinum toxin substrate 1/0.482
2nu9COASuccinate--CoA ligase [ADP-forming] subunit alpha6.2.1.50.481
2pd8FADVivid PAS protein VVD/0.481
3gbuATPUncharacterized sugar kinase PH14592.7.10.481
1equEQIEstradiol 17-beta-dehydrogenase 11.1.1.620.480
3vn2TLSPeroxisome proliferator-activated receptor gamma/0.480
4btjATPTau-tubulin kinase 12.7.11.10.480
4dzzADPPlasmid partitioning protein ParF/0.480
1qlhNADAlcohol dehydrogenase E chain1.1.1.10.479
3hjiFADVivid PAS protein VVD/0.479
3tgpGNPGTPase HRas/0.479
4c4iX20Dual specificity protein kinase TTK2.7.12.10.479
1rj9GCPSignal recognition particle receptor FtsY/0.478
4dmmNAP3-oxoacyl-[acyl-carrier-protein] reductase/0.478
2hwrDRDPeroxisome proliferator-activated receptor gamma/0.477
3jvvACPTwitching mobility protein/0.477
3c15GSPGuanine nucleotide-binding protein G(s) subunit alpha isoforms short/0.476
3cphGDPRas-related protein SEC4/0.476
3qd03Q43-phosphoinositide-dependent protein kinase 12.7.11.10.476
2fe4GDPRas-related protein Rab-6B/0.474
2fg5GNPRas-related protein Rab-31/0.474
3qd43Q63-phosphoinositide-dependent protein kinase 12.7.11.10.474
3rak03ZCyclin-dependent kinase 22.7.11.220.474
3sbdGNPRas-related C3 botulinum toxin substrate 1/0.474
4nu6NADPhosphonate dehydrogenase1.20.1.10.474
1ykdCMPAdenylate cyclase/0.473
2ic5GDPRas-related C3 botulinum toxin substrate 3/0.473
2oo7AP5Adenylate kinase/0.473
3i59N6RCRP-like cAMP-activated global transcriptional regulator/0.473
1y91CT9Cyclin-dependent kinase 22.7.11.220.472
1z2aGDPRas-related protein Rab-23/0.472
2q5p241Peroxisome proliferator-activated receptor gamma/0.472
2j0vGDPRac-like GTP-binding protein ARAC7/0.471
2jamJ60Calcium/calmodulin-dependent protein kinase type 1G2.7.11.170.471
2uw4L15cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.471
3dheANDEstradiol 17-beta-dehydrogenase 11.1.1.620.471
3q0gBCOProbable enoyl-CoA hydratase echA84.2.1.170.471
4hxyNDPPlm1/0.471
4xumIMNPeroxisome proliferator-activated receptor gamma/0.471
3nugNADPyridoxal 4-dehydrogenase1.1.1.1070.470
3r83Z14Cyclin-dependent kinase 22.7.11.220.470
4ehzJAKTyrosine-protein kinase JAK1/0.470
4gojGNPADP-ribosylation factor-like protein 3/0.470
3zu2NAIEnoyl-[acyl-carrier-protein] reductase [NADH]/0.469
5e92ANPTGF-beta receptor type-22.7.11.300.469
2yfeYFEPeroxisome proliferator-activated receptor gamma/0.468
4c4h7RODual specificity protein kinase TTK2.7.12.10.468
4c58824Cyclin-G-associated kinase2.7.11.10.468
4xvrGNPGTPase HRas/0.468
5kczNAJAlcohol dehydrogenase E chain1.1.1.10.468
1glfADPGlycerol kinase/0.467
3ndrNADPyridoxal 4-dehydrogenase1.1.1.1070.467
4paoGSPGuanine nucleotide-binding protein G(i) subunit alpha-1/0.467
1oirHDYCyclin-dependent kinase 22.7.11.220.466
2g0nGDPRas-related C3 botulinum toxin substrate 3/0.466
4m87NADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.466
1oitHDTCyclin-dependent kinase 22.7.11.220.465
4oh4ANPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.465
4z61ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.465
1aj8COACitrate synthase/0.464
1zeoC01Peroxisome proliferator-activated receptor gamma/0.464
2jlcTPP2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase/0.464
3is2FADVivid PAS protein VVD/0.464
3lbhGNPGTPase HRas/0.464
3qbtGNPRas-related protein Rab-8A/0.464
3uhmRFNUDP-3-O-acyl-N-acetylglucosamine deacetylase/0.464
3zw9NADPeroxisomal bifunctional enzyme1.1.1.350.464
5iqiGNPBifunctional AAC/APH2.3.10.464
1ju9NADAlcohol dehydrogenase E chain1.1.1.10.463
1wvgAPRCDP-glucose 4,6-dehydratase4.2.1.450.463
2om9AJAPeroxisome proliferator-activated receptor gamma/0.463
2qmeGCPRas-related C3 botulinum toxin substrate 3/0.463
3tqaNDPDihydrofolate reductase/0.463
4b99R4LMitogen-activated protein kinase 72.7.11.240.463
4v02ATPSite-determining protein/0.463
1tz8DESTransthyretin/0.462
2hmaSAMtRNA-specific 2-thiouridylase MnmA/0.462
2q61SF1Peroxisome proliferator-activated receptor gamma/0.462
2rc6NAPFerredoxin--NADP reductase/0.462
2z4sADPChromosomal replication initiator protein DnaA/0.462
3a20FMNFMN-binding protein/0.462
3k9lGNPGTPase HRas/0.462
3kkqGDPRas-related protein M-Ras/0.462
3kz1GSPTransforming protein RhoA/0.462
4l4xNDPAmphI/0.462
4ly91YYGlucokinase regulatory protein/0.462
5k5zANPUncharacterized protein/0.462
2pd7FADVivid PAS protein VVD/0.461
3ormAGSSerine/threonine protein kinase/0.461
3uzp0CKCasein kinase I isoform delta2.7.11.10.461
4aw1ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.461
4l9sGDPGTPase HRas/0.461
4wa7GDPGTPase KRas/0.461
4yzcSTUSerine/threonine-protein kinase/endoribonuclease IRE12.7.11.10.461
5esoTDP2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase/0.461
3cgfJNFMitogen-activated protein kinase 102.7.11.240.460
3hjkFADVivid PAS protein VVD/0.460
3keuATPPyridoxal kinase2.7.1.350.460
3w32W32Epidermal growth factor receptor2.7.10.10.460
4c4g7RODual specificity protein kinase TTK2.7.12.10.460
4lj9ACPChaperone protein ClpB/0.460
4xuhSFIPeroxisome proliferator-activated receptor gamma/0.460
1kevNDPNADP-dependent isopropanol dehydrogenase1.1.1.800.459
2b9fADPMitogen-activated protein kinase FUS32.7.11.240.459
2hkoFADLysine-specific histone demethylase 1A10.459
2q29ACOOxalyl-CoA decarboxylase4.1.1.80.459
3hwxTPP2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase/0.459
4pl4ADPSerine/threonine-protein kinase/endoribonuclease IRE12.7.11.10.459
1vjy460TGF-beta receptor type-12.7.11.300.458
2b52D42Cyclin-dependent kinase 22.7.11.220.458
2hf8GSPProbable hydrogenase nickel incorporation protein HypB/0.458
2zrjAGSProtein RecA/0.458
3pcfFHBProtocatechuate 3,4-dioxygenase beta chain1.13.11.30.458
3qlrNDPDihydrofolate reductase1.5.1.30.458
3zbnCOA3-ketoacyl-CoA thiolase-like protein/0.458
4an35Y0Dual specificity mitogen-activated protein kinase kinase 12.7.12.20.458
4bwxAGSPAB-dependent poly(A)-specific ribonuclease subunit pan3/0.458
4fv6E57Mitogen-activated protein kinase 12.7.11.240.458
4h4wNAPBiphenyl dioxygenase ferredoxin reductase subunit/0.458
4jr7GNPCasein kinase II subunit alpha2.7.11.10.458
4tq9GDPGTPase KRas/0.458
5iqdGNPBifunctional AAC/APH2.3.10.458
1pmn984Mitogen-activated protein kinase 102.7.11.240.457
3r9xGNPGTPase Era/0.457
3tqhNDPQuinone oxidoreductase/0.457
4du82P0Mevalonate diphosphate decarboxylase/0.457
5dozNDPJamJ/0.457
1edoNAP3-oxoacyl-[acyl-carrier-protein] reductase 1, chloroplastic1.1.1.1000.456
1g6cIFPThiamine-phosphate synthase/0.456
1sn5T3Transthyretin/0.456
2hy0306Serine/threonine-protein kinase Chk12.7.11.10.456
3aw9NADNAD-dependent epimerase/dehydratase/0.456
3cn8FADPolyamine oxidase FMS1/0.456
3i0pNADMalate dehydrogenase, putative/0.456
4bf2STUMitogen-activated protein kinase kinase kinase 52.7.11.250.456
4dymIYZActivin receptor type-12.7.11.300.456
4fv5EK9Mitogen-activated protein kinase 12.7.11.240.456
4l2iFADElectron transfer flavoprotein alpha/beta-subunit/0.456
1j1cADPGlycogen synthase kinase-3 beta2.7.11.260.455
1m2oGNPSmall COPII coat GTPase SAR13.6.50.455
1yu9GNPRas-related protein Rab-4A/0.455
2ce2GDPGTPase HRas/0.455
2p2xSAHDiphthine synthase/0.455
2phkATPPhosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform2.7.11.190.455
2z6dFMNPhototropin-22.7.11.10.455
4dpmCOAMalonyl-CoA reductase1.2.1.750.455
4ktc1X3Genome polyprotein3.4.21.980.455
4wujFMNGlycoside hydrolase family 15, cellulose signaling associated protein envoy/0.455
1bmfANPATP synthase subunit alpha, mitochondrial/0.454
1bmfANPATP synthase subunit beta, mitochondrial3.6.3.140.454
1pxoCK7Cyclin-dependent kinase 22.7.11.220.454
2b9iADPMitogen-activated protein kinase FUS32.7.11.240.454
2j3jHC4NADPH-dependent oxidoreductase 2-alkenal reductase1.3.1.740.454
2wo7ASVIsopenicillin N synthase1.21.3.10.454
3dh7FMNIsopentenyl-diphosphate delta-isomerase/0.454
3n83ADPAldehyde dehydrogenase, mitochondrial1.2.1.30.454
3tsoGNPRas-related protein Rab-25/0.454
4dieC5PCytidylate kinase/0.454
1bwfATFGlycerol kinase/0.453
1qcfPP1Tyrosine-protein kinase HCK2.7.10.20.453
2aa0MTPAdenosine kinase2.7.1.200.453
2gtmLIDMitogen-activated protein kinase 14/0.453
3juqAJDPhenazine biosynthesis protein A/B/0.453
4i3zADPCyclin-dependent kinase 22.7.11.220.453
4j7uNAPSepiapterin reductase1.1.1.1530.453
1dajMOTDihydrofolate reductase1.5.1.30.452
1gotGDPGuanine nucleotide-binding protein G(t) subunit alpha-1/0.452
2b9jADPMitogen-activated protein kinase FUS32.7.11.240.452
2bhiSFTCytotoxin 3/0.452
2gcpGSPRho-related GTP-binding protein RhoC/0.452
3i5zZ48Mitogen-activated protein kinase 12.7.11.240.452
3kkoGNPRas-related protein M-Ras/0.452
4fr4STUSerine/threonine-protein kinase 32A2.7.11.10.452
5kjfNAJAlcohol dehydrogenase E chain1.1.1.10.452
1i44ACPInsulin receptor2.7.10.10.451
1pn3TYDdTDP-epi-vancosaminyltransferase2.4.1.3110.451
1u8vFAD4-hydroxybutyryl-CoA dehydratase/vinylacetyl-CoA-Delta-isomerase/0.451
2ejvNADL-threonine 3-dehydrogenase/0.451
2w4jADPDeath-associated protein kinase 12.7.11.10.451
3iw1ASDSteroid C26-monooxygenase1.14.13.1410.451
3lkiATPFructokinase/0.451
3ruvANPChaperonin/0.451
4awiAQ2Mitogen-activated protein kinase 82.7.11.240.451
4bgePYWEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.451
4fg9ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.451
4lpkGDPGTPase KRas/0.451
4qi5FADCellobiose dehydrogenase/0.451
1dbvNADGlyceraldehyde-3-phosphate dehydrogenase/0.450
1j39UPGDNA beta-glucosyltransferase/0.450
1szjNADGlyceraldehyde-3-phosphate dehydrogenase1.2.1.120.450
1xq6NAPUncharacterized protein At5g02240/0.450
2p9cNAID-3-phosphoglycerate dehydrogenase1.1.1.950.450
2q3eNAIUDP-glucose 6-dehydrogenase1.1.1.220.450
2r7b2533-phosphoinositide-dependent protein kinase 12.7.11.10.450
2v7qATPATP synthase subunit alpha, mitochondrial/0.450
2v7qATPATP synthase subunit beta, mitochondrial3.6.3.140.450
3bbrBHYGlutamate receptor 2/0.450
3fwrADPTranscriptional repressor CcpN/0.450
3rusADPChaperonin/0.450
3w3oROEDihydroorotate dehydrogenase (fumarate)1.3.98.10.450
4bi0Z0WDual specificity protein kinase TTK2.7.12.10.450
4dreNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.450
1eh4IC1Casein kinase I homolog 12.7.11.10.449
1ihxSNDGlyceraldehyde-3-phosphate dehydrogenase1.2.1.120.449
1mruAGSSerine/threonine-protein kinase PknB2.7.11.10.449
1qorNDPQuinone oxidoreductase 1/0.449
2i4pDRHPeroxisome proliferator-activated receptor gamma/0.449
3ad9NADSubunit alpha of sarocosine oxidase/0.449
3cx6GDPGuanine nucleotide-binding protein subunit alpha-13/0.449
4e8yIHAD-beta-D-heptose 7-phosphate kinase/0.449
4fmxCNL1,8-cineole 2-endo-monooxygenase1.14.13.1560.449
4gh5NADShort-chain dehydrogenase/reductase SDR/0.449
4lrjANPUncharacterized protein/0.449
4yswFADXanthine dehydrogenase/oxidase/0.449
1dj3GDPAdenylosuccinate synthetase, chloroplastic/0.448
1jlcFTCGag-Pol polyprotein2.7.7.490.448
1zbdGTPRas-related protein Rab-3A/0.448
2jn3JN3Fatty acid-binding protein, liver/0.448
2opsHBQGag-Pol polyprotein2.7.7.490.448
2ov2GCPRas-related C3 botulinum toxin substrate 3/0.448
3ddcGNPGTPase HRas/0.448
3em6017Gag-Pol polyprotein3.4.23.160.448
3lcdBDYMacrophage colony-stimulating factor 1 receptor2.7.10.10.448
3oom507Activin receptor type-12.7.11.300.448
3qlsNDPDihydrofolate reductase1.5.1.30.448
3v1yNADGlyceraldehyde-3-phosphate dehydrogenase 1, cytosolic1.2.1.120.448
4ewn0VRImidazole glycerol phosphate synthase subunit HisF4.1.30.448
4h3qANPMitogen-activated protein kinase 12.7.11.240.448
4k8aK8AFocal adhesion kinase 12.7.10.20.448
4kl9NDPDihydrofolate reductase1.5.1.30.448
4lv6GDPGTPase KRas/0.448
4oa9ANPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.448
4y0vGDPADP-ribosylation factor 1, putative/0.448
5bsgNAPPyrroline-5-carboxylate reductase/0.448
2a0wDIHPurine nucleoside phosphorylase2.4.2.10.447
2b69NADUDP-glucuronic acid decarboxylase 14.1.1.350.447
2ggsNDPdTDP-4-dehydrorhamnose reductase/0.447
2r26CMCCitrate synthase2.3.3.160.447
2rgeGNPGTPase HRas/0.447
2xvdAS6Ephrin type-B receptor 42.7.10.10.447
2zulSAMProbable ribosomal RNA small subunit methyltransferase/0.447
3dl0AP5Adenylate kinase/0.447
3o9aK14Pol polyprotein/0.447
4c4f7CEDual specificity protein kinase TTK2.7.12.10.447
4fuxE75Mitogen-activated protein kinase 12.7.11.240.447
4fv1EK4Mitogen-activated protein kinase 12.7.11.240.447
4nmbFADBifunctional protein PutA/0.447
5ap57RODual specificity protein kinase TTK2.7.12.10.447
5c88COAN-alpha-acetyltransferase/0.447
1v8kANPKinesin-like protein KIF2C/0.446
1vcfFMNIsopentenyl-diphosphate delta-isomerase/0.446
1wwkNAD307aa long hypothetical phosphoglycerate dehydrogenase/0.446
2ahrNAPPyrroline-5-carboxylate reductase/0.446
2ou2ACOHistone acetyltransferase KAT5/0.446
2yvwEPUUDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.446
3am5TCLEnoyl-ACP reductase/0.446
3cntFADPolyamine oxidase FMS1/0.446
3oibFDAPutative acyl-CoA dehydrogenase/0.446
4g95OAGDihydrofolate reductase1.5.1.30.446
4l49CAMCamphor 5-monooxygenase1.14.15.10.446
4oj4DIFPeroxisome proliferator-activated receptor gamma/0.446
4ztvTA7Anthranilate phosphoribosyltransferase/0.446
5l3rGCPCell division protein FtsY homolog, chloroplastic/0.446
1e96GTPRas-related C3 botulinum toxin substrate 1/0.445
1gp2GDPGuanine nucleotide-binding protein G(i) subunit alpha-1/0.445
1kvsUPGUDP-glucose 4-epimerase5.1.3.20.445
1p7cT5AThymidine kinase/0.445
1unhIXMCyclin-dependent-like kinase 52.7.11.10.445
2p5yNADUDP-glucose 4-epimerase/0.445
3a99ANPSerine/threonine-protein kinase pim-12.7.11.10.445
3hmm855TGF-beta receptor type-12.7.11.300.445
3lt2FT3Enoyl-ACP reductase/0.445
3rlq3RQHeat shock protein HSP 90-alpha/0.445
3zksWZVBeta-secretase 23.4.23.450.445
4c59FEFCyclin-G-associated kinase2.7.11.10.445
4jbiNDPAlcohol dehydrogenase (Zinc)/0.445
4otwDB8Receptor tyrosine-protein kinase erbB-32.7.10.10.445
4u2tFADCholesterol oxidase1.1.3.60.445
4w9wYDJBMP-2-inducible protein kinase2.7.11.10.445
5d3qGDPDynamin-13.6.5.50.445
1aypINBPhospholipase A2, membrane associated/0.444
1d7yFADFerredoxin reductase/0.444
1sezOMNProtoporphyrinogen oxidase, mitochondrial1.3.3.40.444
1z5mLI83-phosphoinositide-dependent protein kinase 12.7.11.10.444
2c5lGTPGTPase HRas/0.444
2eu8AP5Adenylate kinase/0.444
2ozoANPTyrosine-protein kinase ZAP-702.7.10.20.444
3b70NAPEnoyl reductase LovC10.444
3hrfATP3-phosphoinositide-dependent protein kinase 12.7.11.10.444
3r1yX76Cyclin-dependent kinase 22.7.11.220.444
3ruqADPChaperonin/0.444
4c0bATPmRNA cleavage and polyadenylation factor CLP1/0.444
4c3rACPAurora kinase A2.7.11.10.444
4fki09KCyclin-dependent kinase 22.7.11.220.444
4h8nNDPNADPH-dependent conjugated polyketone reductase C2/0.444
4q1y017Gag-Pol polyprotein3.4.23.160.444
4qe6JN3Bile acid receptor/0.444
1bvrNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.443
1fnnADPORC1-type DNA replication protein/0.443
1u2oNECEndoplasmin/0.443
2p9gNAID-3-phosphoglycerate dehydrogenase1.1.1.950.443
2vtrLZBCyclin-dependent kinase 22.7.11.220.443
3bgxTMPThymidylate synthase/0.443
3dl9BCDVitamin D 25-hydroxylase/0.443
3drcMTXDihydrofolate reductase1.5.1.30.443
3dvlATPCircadian clock protein kinase KaiC2.7.11.10.443
3icsADPCoenzyme A disulfide reductase/0.443
3kb1ADPIron-sulfur cluster carrier protein/0.443
3ncrADPNitrogen regulatory protein P-II (GlnB-2)/0.443
3nfaCBJGag-Pol polyprotein/0.443
3ntdCOAFAD-dependent pyridine nucleotide-disulphide oxidoreductase/0.443
3nunJMZ3-phosphoinositide-dependent protein kinase 12.7.11.10.443
3pe6ZYHMonoglyceride lipase/0.443
3uoyNAP2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase1.14.13.1600.443
3vt7VDXVitamin D3 receptor/0.443
4btjADPTau-tubulin kinase 12.7.11.10.443
4g01GDPRas-related protein RABF2b/0.443
4gdy0X1Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.443
4l7f1V5Mitogen-activated protein kinase 82.7.11.240.443
4njsG08Protease/0.443
4zcaADPKinesin-like protein KIF11/0.443
4zohFADPutative oxidoreductase FAD-binding subunit/0.443
5drdATPAurora kinase A2.7.11.10.443
5jlaNADPutative short-chain dehydrogenase/reductase/0.443
1a72PADAlcohol dehydrogenase E chain1.1.1.10.442
1n6lGTPRas-related protein Rab-5A/0.442
1nhtPGSAdenylosuccinate synthetase/0.442
1t09NAPIsocitrate dehydrogenase [NADP] cytoplasmic1.1.1.420.442
1zgdNAPChalcone reductase/0.442
2p83MR0Beta-secretase 13.4.23.460.442
2w9hTOPDihydrofolate reductase1.5.1.30.442
3cx4ADPGlycogen synthase2.4.1.210.442
3lfqA28Cyclin-dependent kinase 22.7.11.220.442
3r4b74TGag-Pol polyprotein/0.442
3zxtACPDeath-associated protein kinase 12.7.11.10.442
4ek816KCyclin-dependent kinase 22.7.11.220.442
4f650S9Fibroblast growth factor receptor 1/0.442
4fryNADPutative signal-transduction protein with CBS domains/0.442
5bsfNADPyrroline-5-carboxylate reductase/0.442
1mg5NAIAlcohol dehydrogenase1.1.1.10.441
1om1IQACasein kinase II subunit alpha2.7.11.10.441
1pdhFASp-hydroxybenzoate hydroxylase/0.441
1rkxNADCDP-D-glucose-4,6-dehydratase/0.441
1rx8NAPDihydrofolate reductase1.5.1.30.441
1tehNADAlcohol dehydrogenase class-31.1.1.10.441
1xddAAYIntegrin alpha-L/0.441
2d2iNAPGlyceraldehyde-3-phosphate dehydrogenase/0.441
2g2hP16Tyrosine-protein kinase ABL12.7.10.20.441
2gr1FADFerredoxin reductase/0.441
2z6cFMNPhototropin-12.7.11.10.441
2zzaFOLDihydrofolate reductase/0.441
3elcF012-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase4.6.1.120.441
3g49NAPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.441
3gqvNAPEnoyl reductase LovC10.441
3kjsNAPBifunctional dihydrofolate reductase-thymidylate synthase/0.441
3lliFADSulfhydryl oxidase 11.8.3.20.441
3nuyJPZ3-phosphoinositide-dependent protein kinase 12.7.11.10.441
4hle17VPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.441
4y8wSTRSteroid 21-hydroxylase/0.441
1drbMTXDihydrofolate reductase1.5.1.30.440
1iolESTEstradiol 17-beta-dehydrogenase 11.1.1.620.440
1t9a1TBAcetolactate synthase catalytic subunit, mitochondrial2.2.1.60.440
1yb5NAPQuinone oxidoreductase1.6.5.50.440
2a94AP0L-lactate dehydrogenase1.1.1.270.440
2bmeGNPRas-related protein Rab-4A/0.440
2dwbANPAurora kinase A2.7.11.10.440
2fonFADAcyl-coenzyme A oxidase/0.440
2givACOHistone acetyltransferase KAT8/0.440
2q8sL92Peroxisome proliferator-activated receptor gamma/0.440
2r5tANPSerine/threonine-protein kinase Sgk12.7.11.10.440
2x6tNAPADP-L-glycero-D-manno-heptose-6-epimerase/0.440
2znoS44Peroxisome proliferator-activated receptor gamma/0.440
3a4vNADNDP-sugar epimerase/0.440
3d72FADVivid PAS protein VVD/0.440
3irm1CYBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.440
3lpiZ74Beta-secretase 13.4.23.460.440
3nieANPMitogen-activated protein kinase/0.440
3qwbNDPProbable quinone oxidoreductase1.6.5.50.440
3v9v21LPeroxisome proliferator-activated receptor gamma/0.440
3wd7COAAcridone synthase/0.440
4aguD15Cyclin-dependent kinase-like 1/0.440
4dit0KDGlycogen synthase kinase-3 beta2.7.11.260.440
4e6d0NUTyrosine-protein kinase JAK2/0.440
4e6q0NVTyrosine-protein kinase JAK2/0.440
4eooATPCyclin-dependent kinase 22.7.11.220.440
4hy6FJ1Heat shock protein HSP 90-alpha/0.440
4o1pANPRibonuclease L/0.440
5adhAPRAlcohol dehydrogenase E chain1.1.1.10.440
5k2bZMAAdenosine receptor A2a/0.440