sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3fly | FLY | Mitogen-activated protein kinase 14 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 3fly | FLY | Mitogen-activated protein kinase 14 | / | 1.000 | |
| 3fmh | 533 | Mitogen-activated protein kinase 14 | / | 0.811 | |
| 3flz | FLZ | Mitogen-activated protein kinase 14 | / | 0.785 | |
| 3fi4 | FI4 | Mitogen-activated protein kinase 14 | / | 0.725 | |
| 3fln | 3FN | Mitogen-activated protein kinase 14 | / | 0.707 | |
| 3flw | FLW | Mitogen-activated protein kinase 14 | / | 0.706 | |
| 3fkl | FKL | Mitogen-activated protein kinase 14 | / | 0.676 | |
| 3fmk | FMK | Mitogen-activated protein kinase 14 | / | 0.652 | |
| 3iph | G11 | Mitogen-activated protein kinase 14 | / | 0.643 | |
| 3fsk | RO6 | Mitogen-activated protein kinase 14 | / | 0.634 | |
| 3hl7 | I47 | Mitogen-activated protein kinase 14 | / | 0.630 | |
| 3nww | 3NW | Mitogen-activated protein kinase 14 | / | 0.615 | |
| 3dt1 | P40 | Mitogen-activated protein kinase 14 | / | 0.609 | |
| 3mpt | 1GK | Mitogen-activated protein kinase 14 | / | 0.599 | |
| 2bal | PQA | Mitogen-activated protein kinase 14 | / | 0.594 | |
| 4lop | SB4 | Mitogen-activated protein kinase 14 | / | 0.585 | |
| 3hvc | GG5 | Mitogen-activated protein kinase 14 | / | 0.572 | |
| 3fls | FLS | Mitogen-activated protein kinase 14 | / | 0.565 | |
| 4aa5 | NQB | Mitogen-activated protein kinase 14 | / | 0.564 | |
| 4aa4 | QC0 | Mitogen-activated protein kinase 14 | / | 0.563 | |
| 3hll | I45 | Mitogen-activated protein kinase 14 | / | 0.562 | |
| 2ghl | LIB | Mitogen-activated protein kinase 14 | / | 0.558 | |
| 4kip | 1R9 | Mitogen-activated protein kinase 14 | / | 0.557 | |
| 3fml | FML | Mitogen-activated protein kinase 14 | / | 0.556 | |
| 3fmn | 530 | Mitogen-activated protein kinase 14 | / | 0.554 | |
| 1ouk | 084 | Mitogen-activated protein kinase 14 | / | 0.549 | |
| 4loo | SB4 | Mitogen-activated protein kinase 14 | / | 0.545 | |
| 3s4q | NK0 | Mitogen-activated protein kinase 14 | / | 0.543 | |
| 4aac | AAV | Mitogen-activated protein kinase 14 | / | 0.543 | |
| 4loq | SB4 | Mitogen-activated protein kinase 14 | / | 0.533 | |
| 2qd9 | LGF | Mitogen-activated protein kinase 14 | / | 0.532 | |
| 2rg6 | 287 | Mitogen-activated protein kinase 14 | / | 0.532 | |
| 3fl4 | FL4 | Mitogen-activated protein kinase 14 | / | 0.525 | |
| 1zz2 | B11 | Mitogen-activated protein kinase 14 | / | 0.523 | |
| 2rg5 | 279 | Mitogen-activated protein kinase 14 | / | 0.520 | |
| 4kin | 1M8 | Mitogen-activated protein kinase 14 | / | 0.517 | |
| 1bl6 | SB6 | Mitogen-activated protein kinase 14 | / | 0.516 | |
| 3u8w | 09J | Mitogen-activated protein kinase 14 | / | 0.516 | |
| 3mvl | 38P | Mitogen-activated protein kinase 14 | / | 0.512 | |
| 4kiq | 1RA | Mitogen-activated protein kinase 14 | / | 0.512 | |
| 1ouy | 094 | Mitogen-activated protein kinase 14 | / | 0.511 | |
| 3fko | FKO | Mitogen-activated protein kinase 14 | / | 0.510 | |
| 3gfe | P37 | Mitogen-activated protein kinase 14 | / | 0.509 | |
| 3roc | 29A | Mitogen-activated protein kinase 14 | / | 0.508 | |
| 1ywr | LI9 | Mitogen-activated protein kinase 14 | / | 0.507 | |
| 1zyj | BI5 | Mitogen-activated protein kinase 14 | / | 0.502 | |
| 3uib | SB2 | Putative mitogen-activated protein kinase | / | 0.497 | |
| 3l8x | N4D | Mitogen-activated protein kinase 14 | / | 0.494 | |
| 3mpa | SB2 | Mitogen-activated protein kinase 14 | / | 0.494 | |
| 4eh7 | 0OO | Mitogen-activated protein kinase 14 | / | 0.494 | |
| 3ocg | OCG | Mitogen-activated protein kinase 14 | / | 0.492 | |
| 5ar4 | SB2 | Receptor-interacting serine/threonine-protein kinase 2 | 2.7.11.1 | 0.491 | |
| 2nry | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.489 | |
| 3b8r | 887 | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.488 | |
| 3gw9 | VNI | Lanosterol 14-alpha-demethylase | / | 0.488 | |
| 4c3f | 7KW | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.488 | |
| 1m7q | DQO | Mitogen-activated protein kinase 14 | / | 0.486 | |
| 2hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.483 | |
| 3hp5 | 52P | Mitogen-activated protein kinase 14 | / | 0.482 | |
| 4nka | 2K7 | Fibroblast growth factor receptor 1 | / | 0.480 | |
| 2zb0 | GK3 | Mitogen-activated protein kinase 14 | / | 0.479 | |
| 4eh6 | 0ON | Mitogen-activated protein kinase 14 | / | 0.479 | |
| 1fwk | ADP | Homoserine kinase | 2.7.1.39 | 0.476 | |
| 2vyn | NAD | Glyceraldehyde-3-phosphate dehydrogenase A | / | 0.476 | |
| 2j5x | GSP | ADP-ribosylation factor 6 | / | 0.474 | |
| 4l4x | NDP | AmphI | / | 0.473 | |
| 4nk9 | 2K5 | Fibroblast growth factor receptor 1 | / | 0.473 | |
| 1bdl | IM1 | Gag-Pol polyprotein | 3.4.23.16 | 0.472 | |
| 3fmj | FMJ | Mitogen-activated protein kinase 14 | / | 0.472 | |
| 4g3j | VNT | Lanosterol 14-alpha-demethylase | / | 0.472 | |
| 4mf0 | 29Z | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.472 | |
| 4ewq | MWL | Mitogen-activated protein kinase 14 | / | 0.471 | |
| 2xik | J60 | Serine/threonine-protein kinase 25 | 2.7.11.1 | 0.470 | |
| 3atz | FMN | Prostaglandin F2a synthase | / | 0.470 | |
| 3fmm | XI2 | Mitogen-activated protein kinase 14 | / | 0.470 | |
| 3mvm | 39P | Mitogen-activated protein kinase 14 | / | 0.469 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.468 | |
| 2qbo | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.468 | |
| 3t11 | 3T1 | Gag-Pol polyprotein | 3.4.23.16 | 0.468 | |
| 4bdi | HAU | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.468 | |
| 4cd2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.468 | |
| 1s0x | C3S | Nuclear receptor ROR-alpha | / | 0.467 | |
| 2q9f | C3S | Cholesterol 24-hydroxylase | / | 0.467 | |
| 3t2z | FAD | Sulfide-quinone reductase | / | 0.467 | |
| 3cjg | KIM | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.466 | |
| 3kf7 | L9G | Mitogen-activated protein kinase 14 | / | 0.466 | |
| 1yw2 | PGJ | Mitogen-activated protein kinase 14 | / | 0.465 | |
| 3ha8 | 5JZ | Mitogen-activated protein kinase 14 | / | 0.465 | |
| 3hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.465 | |
| 4u97 | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.465 | |
| 3b70 | NAP | Enoyl reductase LovC | 1 | 0.464 | |
| 3bv3 | P39 | Mitogen-activated protein kinase 14 | / | 0.464 | |
| 3itz | P66 | Mitogen-activated protein kinase 14 | / | 0.464 | |
| 1f17 | NAI | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.463 | |
| 4bf2 | STU | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.463 | |
| 4epl | JAI | Jasmonic acid-amido synthetase JAR1 | 6.3.2 | 0.463 | |
| 4fw8 | NAI | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.463 | |
| 4nky | 3QZ | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.463 | |
| 2xa4 | AZ5 | Tyrosine-protein kinase JAK2 | / | 0.462 | |
| 1vik | BAY | Gag-Pol polyprotein | / | 0.461 | |
| 1z1r | HBH | Gag-Pol polyprotein | 3.4.23.16 | 0.461 | |
| 2q5k | AB1 | Protease | / | 0.461 | |
| 3mwu | BK3 | Calmodulin-domain protein kinase 1, putative | / | 0.461 | |
| 4hhz | 15S | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.461 | |
| 1k6c | MK1 | Gag-Pol polyprotein | 3.4.23.16 | 0.460 | |
| 1ywn | LIF | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.460 | |
| 2p3b | 3TL | V-1 PROTEASE protein | / | 0.460 | |
| 2p3b | 3TL | V-1 protease | / | 0.460 | |
| 3hx4 | ANP | Calmodulin-domain protein kinase 1 | / | 0.460 | |
| 3kpk | FAD | Sulfide-quinone reductase | / | 0.460 | |
| 3lsh | FAD | Pyranose 2-oxidase | / | 0.460 | |
| 3p6p | A6B | Camphor 5-monooxygenase | 1.14.15.1 | 0.460 | |
| 3sp6 | IL2 | Peroxisome proliferator-activated receptor alpha | / | 0.460 | |
| 4anq | VGH | ALK tyrosine kinase receptor | 2.7.10.1 | 0.460 | |
| 4g74 | FAD | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.460 | |
| 4hdb | G52 | Gag-Pol polyprotein | 3.4.23.16 | 0.460 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.459 | |
| 1nvt | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.459 | |
| 2fto | CB3 | Thymidylate synthase | / | 0.459 | |
| 2gfs | PQB | Mitogen-activated protein kinase 14 | / | 0.459 | |
| 3cbl | STU | Tyrosine-protein kinase Fes/Fps | 2.7.10.2 | 0.459 | |
| 4fod | 0UV | ALK tyrosine kinase receptor | 2.7.10.1 | 0.459 | |
| 3vid | 4TT | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.458 | |
| 3v8w | 0G2 | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.457 | |
| 1kbo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.456 | |
| 1noo | CAH | Camphor 5-monooxygenase | 1.14.15.1 | 0.456 | |
| 2iko | 7IG | Renin | 3.4.23.15 | 0.456 | |
| 3gst | GPR | Glutathione S-transferase Mu 1 | 2.5.1.18 | 0.456 | |
| 3vye | VYE | Renin | 3.4.23.15 | 0.456 | |
| 4hp8 | NAP | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.456 | |
| 1bmk | SB5 | Mitogen-activated protein kinase 14 | / | 0.455 | |
| 1n83 | CLR | Nuclear receptor ROR-alpha | / | 0.455 | |
| 1qbg | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.455 | |
| 2zaz | GK1 | Mitogen-activated protein kinase 14 | / | 0.455 | |
| 3ggp | NAD | Prephenate dehydrogenase | / | 0.455 | |
| 3o8t | BMU | Mitogen-activated protein kinase 14 | / | 0.455 | |
| 3uku | C69 | Actin-related protein 3 | / | 0.455 | |
| 4nfn | 2KC | Tau-tubulin kinase 1 | 2.7.11.1 | 0.455 | |
| 1agw | SU2 | Fibroblast growth factor receptor 1 | / | 0.454 | |
| 1k6p | XN3 | Gag-Pol polyprotein | 3.4.23.16 | 0.454 | |
| 1msm | JE2 | Gag-Pol polyprotein | 3.4.23.16 | 0.454 | |
| 2ft9 | CHD | Fatty acid-binding protein 2, liver | / | 0.454 | |
| 2nru | T12 | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.454 | |
| 3ieu | GDP | GTPase Era | / | 0.454 | |
| 3ol5 | SAW | Camphor 5-monooxygenase | 1.14.15.1 | 0.454 | |
| 4kbc | 1QJ | Casein kinase I isoform delta | 2.7.11.1 | 0.454 | |
| 4xum | IMN | Peroxisome proliferator-activated receptor gamma | / | 0.454 | |
| 1xl5 | 190 | Gag-Pol polyprotein | 3.4.23.16 | 0.453 | |
| 2igo | FAD | Pyranose 2-oxidase | / | 0.453 | |
| 3ma3 | 01I | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.453 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.453 | |
| 4ic7 | ANP | Mitogen-activated protein kinase 7 | 2.7.11.24 | 0.453 | |
| 4qmx | H8H | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.453 | |
| 1jpa | ANP | Ephrin type-B receptor 2 | 2.7.10.1 | 0.452 | |
| 1szm | BI4 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.452 | |
| 2uzl | C94 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.452 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.452 | |
| 3o9g | F53 | Gag-Pol polyprotein | / | 0.452 | |
| 3oog | YTP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.452 | |
| 3sab | F78 | Protease | / | 0.452 | |
| 3u9n | 09H | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.452 | |
| 4aox | FAD | Steroid monooxygenase | / | 0.452 | |
| 4hbg | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | 1.1.1.100 | 0.452 | |
| 4jx1 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.452 | |
| 1dhr | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.451 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.451 | |
| 1lso | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.451 | |
| 1w06 | W05 | Isopenicillin N synthase | 1.21.3.1 | 0.451 | |
| 3iae | D7K | Benzaldehyde lyase | / | 0.451 | |
| 3mdv | CL6 | Cholesterol 24-hydroxylase | / | 0.451 | |
| 1bxo | PP7 | Penicillopepsin-1 | 3.4.23.20 | 0.450 | |
| 1byg | STU | Tyrosine-protein kinase CSK | / | 0.450 | |
| 1rbz | KT5 | Trifunctional purine biosynthetic protein adenosine-3 | 2.1.2.2 | 0.450 | |
| 1re7 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 1t88 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.450 | |
| 1yqj | 6NP | Mitogen-activated protein kinase 14 | / | 0.450 | |
| 2f1k | NAP | Prephenate dehydrogenase | / | 0.450 | |
| 3d91 | REM | Renin | 3.4.23.15 | 0.450 | |
| 4ei7 | GDP | Plasmid replication protein RepX | / | 0.450 | |
| 4ez8 | DHF | Thymidylate synthase | 2.1.1.45 | 0.450 | |
| 4ft7 | H3K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.450 | |
| 5cpb | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.450 | |
| 5d3q | GDP | Dynamin-1 | 3.6.5.5 | 0.450 | |
| 2aqu | DR7 | Gag-Pol polyprotein | 3.4.23.16 | 0.449 | |
| 2obj | VRV | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.449 | |
| 3a99 | ANP | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.449 | |
| 3dhe | AND | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.449 | |
| 3fwi | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.449 | |
| 3zsh | 469 | Mitogen-activated protein kinase 14 | / | 0.449 | |
| 5a3b | APR | SIR2 family protein | / | 0.449 | |
| 2bro | DF2 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.448 | |
| 2g1o | 2IG | Renin | 3.4.23.15 | 0.448 | |
| 2qbl | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.448 | |
| 2qbm | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.448 | |
| 2qd7 | 065 | Gag-Pol polyprotein | 3.4.23.16 | 0.448 | |
| 2vd5 | BI8 | Myotonin-protein kinase | 2.7.11.1 | 0.448 | |
| 3a1n | NAD | NDP-sugar epimerase | / | 0.448 | |
| 3bv2 | P38 | Mitogen-activated protein kinase 14 | / | 0.448 | |
| 3gi6 | D78 | Gag-Pol polyprotein | / | 0.448 | |
| 3l63 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.448 | |
| 4gk3 | L87 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.448 | |
| 5a4k | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.448 | |
| 1zrz | BI1 | Protein kinase C iota type | 2.7.11.13 | 0.447 | |
| 2y5k | YCU | Fructose-1,6-bisphosphatase 1 | 3.1.3.11 | 0.447 | |
| 3e5r | NAD | Glyceraldehyde-3-phosphate dehydrogenase 1, cytosolic | 1.2.1.12 | 0.447 | |
| 3fsf | FSS | Mitogen-activated protein kinase 14 | / | 0.447 | |
| 3ggx | GGX | Gag-Pol polyprotein | / | 0.447 | |
| 3t8o | ATP | Rhodopsin kinase | / | 0.447 | |
| 4gk2 | L66 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.447 | |
| 4hxy | NDP | Plm1 | / | 0.447 | |
| 4nbw | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.447 | |
| 4tuv | CPZ | Cytochrome P450 119 | 1.14 | 0.447 | |
| 1nvq | UCN | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.446 | |
| 2c3q | GTX | Glutathione S-transferase theta-1 | 2.5.1.18 | 0.446 | |
| 2ien | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.446 | |
| 2qo9 | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.446 | |
| 3syi | FAD | Sulfide-quinone reductase | / | 0.446 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.446 | |
| 4g7g | VFV | Lanosterol 14-alpha-demethylase | / | 0.446 | |
| 4gh5 | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.446 | |
| 4n5n | NAP | Acetoacetyl-CoA reductase | 1.1.1.36 | 0.446 | |
| 1jgt | APC | Carboxyethyl-arginine beta-lactam-synthase | 6.3.3.4 | 0.445 | |
| 1xe5 | 5FE | Plasmepsin-2 | 3.4.23.39 | 0.445 | |
| 2oor | NAD | NAD(P) transhydrogenase subunit alpha part 1 | 1.6.1.2 | 0.445 | |
| 2r5t | ANP | Serine/threonine-protein kinase Sgk1 | 2.7.11.1 | 0.445 | |
| 3gc9 | B45 | Mitogen-activated protein kinase 11 | 2.7.11.24 | 0.445 | |
| 3ndx | RIT | Gag-Pol polyprotein | 3.4.23.16 | 0.445 | |
| 3oag | LPQ | Renin | 3.4.23.15 | 0.445 | |
| 3sa6 | F71 | Protease | / | 0.445 | |
| 3w33 | W19 | Epidermal growth factor receptor | 2.7.10.1 | 0.445 | |
| 4d0l | 093 | Phosphatidylinositol 4-kinase beta | 2.7.1.67 | 0.445 | |
| 4i8z | G08 | Gag-Pol polyprotein | 3.4.23.16 | 0.445 | |
| 1h69 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.444 | |
| 1ke9 | LS5 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.444 | |
| 1t85 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.444 | |
| 1zxm | ANP | DNA topoisomerase 2-alpha | 5.99.1.3 | 0.444 | |
| 2dte | NAI | Glucose 1-dehydrogenase related protein | / | 0.444 | |
| 2qi4 | MZ6 | Gag-Pol polyprotein | / | 0.444 | |
| 2qi7 | MZ9 | Gag-Pol polyprotein | / | 0.444 | |
| 2vzm | NRB | Cytochrome P450 monooxygenase PikC | / | 0.444 | |
| 3eky | DR7 | Gag-Pol polyprotein | 3.4.23.16 | 0.444 | |
| 3ggo | NAI | Prephenate dehydrogenase | / | 0.444 | |
| 3n0t | OPY | Dipeptidyl peptidase 2 | 3.4.14.2 | 0.444 | |
| 3qt6 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.444 | |
| 3sx2 | NAD | Uncharacterized protein | / | 0.444 | |
| 4l49 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.444 | |
| 5e8w | STU | TGF-beta receptor type-1 | 2.7.11.30 | 0.444 | |
| 1c6z | ROC | Protease | / | 0.443 | |
| 1dw6 | 0Q4 | Gag-Pol polyprotein | 3.4.23.16 | 0.443 | |
| 1gg5 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.443 | |
| 1nvs | UCM | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.443 | |
| 1phh | FAD | p-hydroxybenzoate hydroxylase | / | 0.443 | |
| 1sh9 | RIT | Gag-Pol polyprotein | 3.4.23.16 | 0.443 | |
| 1vij | BAY | Gag-Pol polyprotein | / | 0.443 | |
| 2a1m | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 2o23 | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.443 | |
| 3c1t | MYC | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.443 | |
| 3gi5 | K62 | Gag-Pol polyprotein | / | 0.443 | |
| 3inv | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.443 | |
| 3lct | ADP | ALK tyrosine kinase receptor | 2.7.10.1 | 0.443 | |
| 3own | 3OW | Renin | 3.4.23.15 | 0.443 | |
| 3sac | AF8 | Protease | / | 0.443 | |
| 4b4w | 9L9 | Bifunctional protein FolD | / | 0.443 | |
| 4g95 | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 4kl9 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 4yr9 | NAD | L-threonine 3-dehydrogenase, mitochondrial | 1.1.1.103 | 0.443 | |
| 6cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 1dyj | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1hvs | A77 | Gag-Pol polyprotein | / | 0.442 | |
| 1o76 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 1x2h | LPA | Lipoate-protein ligase A | 6.3.1.20 | 0.442 | |
| 1y57 | MPZ | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.442 | |
| 2gcg | NDP | Glyoxylate reductase/hydroxypyruvate reductase | 1.1.1.79 | 0.442 | |
| 2zgy | GDP | Plasmid segregation protein ParM | / | 0.442 | |
| 2zui | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 3ekq | ROC | Gag-Pol polyprotein | 3.4.23.16 | 0.442 | |
| 3th8 | TH9 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.442 | |
| 3v5l | 0G1 | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.442 | |
| 4bkz | 1WS | Maternal embryonic leucine zipper kinase | 2.7.11.1 | 0.442 | |
| 4ftq | 4HK | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.442 | |
| 4ix6 | ADP | Uncharacterized protein | / | 0.442 | |
| 4ly9 | 1YY | Glucokinase regulatory protein | / | 0.442 | |
| 4y35 | F90 | Endothiapepsin | 3.4.23.22 | 0.442 | |
| 1gzu | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 | 2.7.7.1 | 0.441 | |
| 1mvs | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 2e9o | A58 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.441 | |
| 2oh0 | 2PY | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.441 | |
| 2qi6 | MZ8 | Gag-Pol polyprotein | / | 0.441 | |
| 3cmc | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.441 | |
| 3l8s | BFF | Mitogen-activated protein kinase 14 | / | 0.441 | |
| 3rwp | ABQ | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.441 | |
| 3zpt | M8Y | Gag-Pol polyprotein | 3.4.23.16 | 0.441 | |
| 4b4v | L34 | Bifunctional protein FolD | / | 0.441 | |
| 4fr4 | STU | Serine/threonine-protein kinase 32A | 2.7.11.1 | 0.441 | |
| 4hvh | 19R | Tyrosine-protein kinase JAK3 | 2.7.10.2 | 0.441 | |
| 4ien | COA | Putative acyl-CoA hydrolase | / | 0.441 | |
| 1dz4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 1hdc | CBO | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.440 | |
| 1hii | C20 | Gag-Pol polyprotein | / | 0.440 | |
| 1nqo | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.440 | |
| 1oiy | N41 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 | |
| 1qr6 | NAD | NAD-dependent malic enzyme, mitochondrial | 1.1.1.38 | 0.440 | |
| 1t7k | BH0 | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
| 1u7t | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.440 | |
| 1y0s | 331 | Peroxisome proliferator-activated receptor delta | / | 0.440 | |
| 2azn | NAP | 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate reductase | / | 0.440 | |
| 2ev9 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.440 | |
| 2exc | JNK | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.440 | |
| 2f4b | EHA | Peroxisome proliferator-activated receptor gamma | / | 0.440 | |
| 2i0d | MUT | Protease | / | 0.440 | |
| 2idw | 017 | Protease | / | 0.440 | |
| 2vx1 | 7X8 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.440 | |
| 2y6o | 1N1 | Ephrin type-A receptor 4 | 2.7.10.1 | 0.440 | |
| 3el5 | 1UN | Gag-Pol polyprotein | / | 0.440 | |
| 3gqv | NAP | Enoyl reductase LovC | 1 | 0.440 | |
| 3nug | NAD | Pyridoxal 4-dehydrogenase | 1.1.1.107 | 0.440 | |
| 3zw9 | NAD | Peroxisomal bifunctional enzyme | 1.1.1.35 | 0.440 | |
| 4b99 | R4L | Mitogen-activated protein kinase 7 | 2.7.11.24 | 0.440 | |
| 4dc0 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.440 | |
| 4dqc | 017 | Gag-Pol polyprotein | / | 0.440 | |
| 4p8r | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.440 | |
| 4wkq | IRE | Epidermal growth factor receptor | 2.7.10.1 | 0.440 |