Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3b8r | 887 | Vascular endothelial growth factor receptor 2 | 2.7.10.1 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 3b8r | 887 | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 1.000 | |
| 4dgg | I76 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.598 | |
| 4nka | 2K7 | Fibroblast growth factor receptor 1 | / | 0.591 | |
| 3b2w | 9NH | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.589 | |
| 2p2h | 994 | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.585 | |
| 3vs6 | VSH | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.574 | |
| 3s4q | NK0 | Mitogen-activated protein kinase 14 | / | 0.572 | |
| 2hk5 | 1BM | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.564 | |
| 3vs4 | VSF | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.564 | |
| 4fic | 0UL | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.561 | |
| 4y93 | 746 | Tyrosine-protein kinase | / | 0.553 | |
| 3cjg | KIM | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.552 | |
| 2of4 | 979 | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.550 | |
| 3vrz | VRZ | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.549 | |
| 1m17 | AQ4 | Epidermal growth factor receptor | 2.7.10.1 | 0.547 | |
| 4mxo | DB8 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.546 | |
| 3qlf | PD5 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.544 | |
| 3vs7 | KS1 | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.543 | |
| 3vjo | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.542 | |
| 3qlg | 1N1 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.541 | |
| 4f64 | 0S8 | Fibroblast growth factor receptor 1 | / | 0.541 | |
| 3bbt | FMM | Receptor tyrosine-protein kinase erbB-4 | 2.7.10.1 | 0.539 | |
| 2c0i | L1G | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.537 | |
| 4nks | 2M2 | Fibroblast growth factor receptor 1 | / | 0.536 | |
| 2bdf | 24A | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.535 | |
| 4i22 | IRE | Epidermal growth factor receptor | 2.7.10.1 | 0.533 | |
| 1qpd | STU | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.532 | |
| 2bdj | HET | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.532 | |
| 2ivu | ZD6 | Proto-oncogene tyrosine-protein kinase receptor Ret | 2.7.10.1 | 0.532 | |
| 3vry | B43 | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.532 | |
| 2of2 | 547 | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.531 | |
| 3vid | 4TT | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.531 | |
| 4bc6 | XZN | Serine/threonine-protein kinase 10 | 2.7.11.1 | 0.528 | |
| 2c0t | L3G | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.527 | |
| 2cdz | 23D | Serine/threonine-protein kinase PAK 4 | 2.7.11.1 | 0.527 | |
| 5aaa | VGH | ALK tyrosine kinase receptor | 2.7.10.1 | 0.525 | |
| 4c62 | XWW | Tyrosine-protein kinase JAK2 | / | 0.524 | |
| 4aa5 | NQB | Mitogen-activated protein kinase 14 | / | 0.523 | |
| 4xey | 1N1 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.522 | |
| 2eb3 | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.521 | |
| 2vwx | 7X4 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.521 | |
| 4j97 | ACP | Fibroblast growth factor receptor 2 | / | 0.521 | |
| 4k11 | 0J9 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.521 | |
| 3w33 | W19 | Epidermal growth factor receptor | 2.7.10.1 | 0.520 | |
| 4kiq | 1RA | Mitogen-activated protein kinase 14 | / | 0.520 | |
| 2dq7 | STU | Tyrosine-protein kinase Fyn | 2.7.10.2 | 0.519 | |
| 3ac5 | KZM | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.518 | |
| 4hjo | AQ4 | Epidermal growth factor receptor | 2.7.10.1 | 0.518 | |
| 3b8q | 900 | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.517 | |
| 4anq | VGH | ALK tyrosine kinase receptor | 2.7.10.1 | 0.515 | |
| 4i23 | 1C9 | Epidermal growth factor receptor | 2.7.10.1 | 0.515 | |
| 3uvq | FS8 | Mitogen-activated protein kinase 14 | / | 0.514 | |
| 4y95 | 746 | Tyrosine-protein kinase | / | 0.514 | |
| 1qpe | PP2 | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.513 | |
| 4xli | 1N1 | Abelson tyrosine-protein kinase 2 | 2.7.10.2 | 0.513 | |
| 4mxx | DB8 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.511 | |
| 1yol | S03 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.509 | |
| 2y6o | 1N1 | Ephrin type-A receptor 4 | 2.7.10.1 | 0.509 | |
| 2zva | 1N1 | Tyrosine-protein kinase Lyn | 2.7.10.2 | 0.509 | |
| 2c0o | L2G | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.507 | |
| 2zm1 | KSF | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.507 | |
| 3dt1 | P40 | Mitogen-activated protein kinase 14 | / | 0.507 | |
| 3lmg | ANP | Receptor tyrosine-protein kinase erbB-3 | 2.7.10.1 | 0.507 | |
| 3fkl | FKL | Mitogen-activated protein kinase 14 | / | 0.506 | |
| 4gk2 | L66 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.506 | |
| 3w2r | W2R | Epidermal growth factor receptor | 2.7.10.1 | 0.505 | |
| 1zyj | BI5 | Mitogen-activated protein kinase 14 | / | 0.503 | |
| 4otw | DB8 | Receptor tyrosine-protein kinase erbB-3 | 2.7.10.1 | 0.503 | |
| 5ajq | DB8 | Serine/threonine-protein kinase 10 | 2.7.11.1 | 0.503 | |
| 1y57 | MPZ | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.502 | |
| 5e8x | STU | TGF-beta receptor type-1 | 2.7.11.30 | 0.502 | |
| 2py3 | ACP | Fibroblast growth factor receptor 2 | / | 0.501 | |
| 2h8h | H8H | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.500 | |
| 2pzr | ACP | Fibroblast growth factor receptor 2 | / | 0.500 | |
| 2vx1 | 7X8 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.500 | |
| 3mpt | 1GK | Mitogen-activated protein kinase 14 | / | 0.499 | |
| 3mvl | 38P | Mitogen-activated protein kinase 14 | / | 0.499 | |
| 4fob | 0US | ALK tyrosine kinase receptor | 2.7.10.1 | 0.499 | |
| 4jq8 | KJ8 | Epidermal growth factor receptor | 2.7.10.1 | 0.499 | |
| 2xp2 | VGH | ALK tyrosine kinase receptor | 2.7.10.1 | 0.498 | |
| 2qo9 | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.497 | |
| 3el8 | PD5 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.497 | |
| 2vwz | 7X6 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.496 | |
| 2vx0 | 7X7 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.496 | |
| 3w2s | W2R | Epidermal growth factor receptor | 2.7.10.1 | 0.496 | |
| 4jq7 | KJQ | Epidermal growth factor receptor | 2.7.10.1 | 0.496 | |
| 2itn | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.495 | |
| 2yn8 | STU | Ephrin type-B receptor 4 | 2.7.10.1 | 0.495 | |
| 2zv9 | PP2 | Tyrosine-protein kinase Lyn | 2.7.10.2 | 0.494 | |
| 3ac2 | KSE | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.494 | |
| 3gfe | P37 | Mitogen-activated protein kinase 14 | / | 0.493 | |
| 4f63 | 0S7 | Fibroblast growth factor receptor 1 | / | 0.493 | |
| 2bal | PQA | Mitogen-activated protein kinase 14 | / | 0.492 | |
| 2zb0 | GK3 | Mitogen-activated protein kinase 14 | / | 0.492 | |
| 4lgh | 0JN | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.492 | |
| 5amn | DTQ | Proto-oncogene tyrosine-protein kinase receptor Ret | 2.7.10.1 | 0.492 | |
| 2fb8 | 215 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.491 | |
| 4qmn | DB8 | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.491 | |
| 4riy | ANP | Receptor tyrosine-protein kinase erbB-3 | 2.7.10.1 | 0.491 | |
| 2itz | IRE | Epidermal growth factor receptor | 2.7.10.1 | 0.490 | |
| 3c7q | XIN | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.490 | |
| 4fnz | NZF | ALK tyrosine kinase receptor | 2.7.10.1 | 0.490 | |
| 4g2f | C07 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.490 | |
| 4lgg | VGG | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.490 | |
| 1di9 | MSQ | Mitogen-activated protein kinase 14 | / | 0.489 | |
| 2pvy | ACP | Fibroblast growth factor receptor 2 | / | 0.489 | |
| 2vwy | 7X5 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.489 | |
| 2pwl | ACP | Fibroblast growth factor receptor 2 | / | 0.488 | |
| 2itp | AEE | Epidermal growth factor receptor | 2.7.10.1 | 0.487 | |
| 3ad6 | KSC | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.487 | |
| 3ocg | OCG | Mitogen-activated protein kinase 14 | / | 0.487 | |
| 4aot | GW8 | Serine/threonine-protein kinase 10 | 2.7.11.1 | 0.487 | |
| 4gk3 | L87 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.487 | |
| 4kin | 1M8 | Mitogen-activated protein kinase 14 | / | 0.487 | |
| 2i0e | PDS | Protein kinase C beta type | 2.7.11.13 | 0.486 | |
| 2itt | AEE | Epidermal growth factor receptor | 2.7.10.1 | 0.486 | |
| 3iph | G11 | Mitogen-activated protein kinase 14 | / | 0.486 | |
| 4m69 | ANP | Receptor-interacting serine/threonine-protein kinase 3 | 2.7.11.1 | 0.486 | |
| 2itw | ITQ | Epidermal growth factor receptor | 2.7.10.1 | 0.485 | |
| 2zyb | KSL | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.485 | |
| 3vs0 | VS0 | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.485 | |
| 4c8b | 0LI | Receptor-interacting serine/threonine-protein kinase 2 | 2.7.11.1 | 0.484 | |
| 2f4j | VX6 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.483 | |
| 2pzp | ACP | Fibroblast growth factor receptor 2 | / | 0.483 | |
| 3ac3 | KSH | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.483 | |
| 4wkq | IRE | Epidermal growth factor receptor | 2.7.10.1 | 0.483 | |
| 1xkk | FMM | Epidermal growth factor receptor | 2.7.10.1 | 0.482 | |
| 2ivv | PP1 | Proto-oncogene tyrosine-protein kinase receptor Ret | 2.7.10.1 | 0.482 | |
| 2qo7 | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.482 | |
| 3ue4 | DB8 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.482 | |
| 4jrv | KJV | Epidermal growth factor receptor | 2.7.10.1 | 0.482 | |
| 4mxy | DB8 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.482 | |
| 4mxz | DB8 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.482 | |
| 3cjf | SAV | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.481 | |
| 3fln | 3FN | Mitogen-activated protein kinase 14 | / | 0.481 | |
| 3hll | I45 | Mitogen-activated protein kinase 14 | / | 0.481 | |
| 3uvp | 048 | Mitogen-activated protein kinase 14 | / | 0.481 | |
| 4l7s | G7K | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.481 | |
| 3l8x | N4D | Mitogen-activated protein kinase 14 | / | 0.480 | |
| 1szm | BI4 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.479 | |
| 2rg6 | 287 | Mitogen-activated protein kinase 14 | / | 0.478 | |
| 2vww | 7X2 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.478 | |
| 2yfx | VGH | ALK tyrosine kinase receptor | 2.7.10.1 | 0.478 | |
| 4fk3 | 325 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.478 | |
| 4fsq | HK3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.478 | |
| 4hvh | 19R | Tyrosine-protein kinase JAK3 | 2.7.10.2 | 0.478 | |
| 4bdd | Z0O | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.477 | |
| 1oec | AA2 | Fibroblast growth factor receptor 2 | / | 0.476 | |
| 4ks8 | B49 | Serine/threonine-protein kinase PAK 6 | 2.7.11.1 | 0.476 | |
| 3nww | 3NW | Mitogen-activated protein kinase 14 | / | 0.475 | |
| 4eqc | XR1 | Serine/threonine-protein kinase PAK 1 | 2.7.11.1 | 0.475 | |
| 4riy | ADP | Epidermal growth factor receptor | 2.7.10.1 | 0.475 | |
| 2gs7 | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.474 | |
| 4bib | IEO | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.474 | |
| 4qmx | H8H | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.474 | |
| 2hog | 710 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.473 | |
| 2itq | ITQ | Epidermal growth factor receptor | 2.7.10.1 | 0.473 | |
| 2pz5 | ACP | Fibroblast growth factor receptor 2 | / | 0.473 | |
| 3vs1 | VSA | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.473 | |
| 4bdh | WVI | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.473 | |
| 4gmy | 0X5 | Tyrosine-protein kinase JAK2 | / | 0.473 | |
| 3ac1 | KZI | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.472 | |
| 1nvs | UCM | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.471 | |
| 2ayp | 43A | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.471 | |
| 2r0u | M54 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.471 | |
| 3be2 | RAJ | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.471 | |
| 3f5p | 741 | Insulin-like growth factor 1 receptor | 2.7.10.1 | 0.471 | |
| 4ans | VGH | ALK tyrosine kinase receptor | 2.7.10.1 | 0.470 | |
| 4bf2 | STU | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.470 | |
| 1ywr | LI9 | Mitogen-activated protein kinase 14 | / | 0.469 | |
| 2rg5 | 279 | Mitogen-activated protein kinase 14 | / | 0.469 | |
| 3gub | GUB | Death-associated protein kinase 1 | 2.7.11.1 | 0.469 | |
| 4flh | 14K | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.469 | |
| 5hes | 032 | Mitogen-activated protein kinase kinase kinase 20 | 2.7.11.25 | 0.469 | |
| 2zm4 | KSM | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.468 | |
| 3b2t | M33 | Fibroblast growth factor receptor 2 | / | 0.468 | |
| 3fmk | FMK | Mitogen-activated protein kinase 14 | / | 0.467 | |
| 4bdc | ODH | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.467 | |
| 2wou | ZZF | TGF-beta receptor type-1 | 2.7.11.30 | 0.466 | |
| 3acj | KSS | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.466 | |
| 3flw | FLW | Mitogen-activated protein kinase 14 | / | 0.466 | |
| 3gc9 | B45 | Mitogen-activated protein kinase 11 | 2.7.11.24 | 0.466 | |
| 3lij | ANP | Calcium/calmodulin dependent protein kinase with a kinase domain and 4 calmodulin like EF hands | / | 0.466 | |
| 4bid | IE8 | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.466 | |
| 4ic7 | ANP | Mitogen-activated protein kinase 7 | 2.7.11.24 | 0.466 | |
| 4lop | SB4 | Mitogen-activated protein kinase 14 | / | 0.466 | |
| 5aac | VGH | ALK tyrosine kinase receptor | 2.7.10.1 | 0.466 | |
| 4yuq | KS1 | Calmodulin-like domain protein kinase | / | 0.465 | |
| 2itv | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.464 | |
| 3poz | 03P | Epidermal growth factor receptor | 2.7.10.1 | 0.464 | |
| 3q5i | ANP | Protein kinase, putative | / | 0.464 | |
| 4c61 | LMM | Tyrosine-protein kinase JAK2 | / | 0.464 | |
| 1byg | STU | Tyrosine-protein kinase CSK | / | 0.463 | |
| 3hl7 | I47 | Mitogen-activated protein kinase 14 | / | 0.463 | |
| 4id7 | 1G0 | Activated CDC42 kinase 1 | / | 0.463 | |
| 4z34 | ON7 | Lysophosphatidic acid receptor 1 | / | 0.463 | |
| 2c6e | HPM | Aurora kinase A | 2.7.11.1 | 0.462 | |
| 2qoc | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.462 | |
| 3tuc | FPW | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.462 | |
| 4dit | 0KD | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.462 | |
| 4kip | 1R9 | Mitogen-activated protein kinase 14 | / | 0.462 | |
| 2gcd | STU | Serine/threonine-protein kinase TAO2 | 2.7.11.1 | 0.461 | |
| 2vd5 | BI8 | Myotonin-protein kinase | 2.7.11.1 | 0.461 | |
| 4dce | 0JF | ALK tyrosine kinase receptor | 2.7.10.1 | 0.461 | |
| 2xyu | Q9G | Ephrin type-A receptor 4 | 2.7.10.1 | 0.460 | |
| 2ym7 | YM7 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.460 | |
| 3fi4 | FI4 | Mitogen-activated protein kinase 14 | / | 0.460 | |
| 4ftk | H9K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.460 | |
| 1e90 | MYC | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.459 | |
| 2j7t | 274 | Serine/threonine-protein kinase 10 | 2.7.11.1 | 0.459 | |
| 3aox | EMH | ALK tyrosine kinase receptor | 2.7.10.1 | 0.459 | |
| 3el7 | PD3 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.459 | |
| 3flz | FLZ | Mitogen-activated protein kinase 14 | / | 0.459 | |
| 3l8p | 0CE | Angiopoietin-1 receptor | 2.7.10.1 | 0.459 | |
| 4aa4 | QC0 | Mitogen-activated protein kinase 14 | / | 0.459 | |
| 4ftm | 1HK | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.459 | |
| 4uya | AGS | Mitogen-activated protein kinase kinase kinase 21 | 2.7.11.25 | 0.459 | |
| 2hy8 | 1ST | Serine/threonine-protein kinase PAK 1 | 2.7.11.1 | 0.458 | |
| 3a4o | STU | Tyrosine-protein kinase Lyn | 2.7.10.2 | 0.458 | |
| 3ncg | BK1 | Calmodulin-domain protein kinase 1, putative | / | 0.458 | |
| 2e9n | 76A | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.457 | |
| 3g0e | B49 | Mast/stem cell growth factor receptor Kit | 2.7.10.1 | 0.457 | |
| 4feq | 0T8 | Tyrosine-protein kinase receptor TYRO3 | 2.7.10.1 | 0.457 | |
| 4kl9 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.457 | |
| 2w0j | ZAT | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.456 | |
| 3fly | FLY | Mitogen-activated protein kinase 14 | / | 0.456 | |
| 4fl3 | ANP | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.456 | |
| 2x2l | X2L | Proto-oncogene tyrosine-protein kinase receptor Ret | 2.7.10.1 | 0.455 | |
| 2ycq | UPX | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.455 | |
| 2ydi | YDI | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.455 | |
| 3hx4 | ANP | Calmodulin-domain protein kinase 1 | / | 0.455 | |
| 4bb4 | 32W | Ephrin type-B receptor 4 | 2.7.10.1 | 0.455 | |
| 4bdb | ODO | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.455 | |
| 4g34 | 924 | Eukaryotic translation initiation factor 2-alpha kinase 3 | 2.7.11.1 | 0.455 | |
| 4hgt | 15G | Casein kinase I isoform delta | 2.7.11.1 | 0.455 | |
| 4ieb | ANP | Calmodulin-domain protein kinase 1 | / | 0.455 | |
| 5d12 | G97 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.455 | |
| 1agw | SU2 | Fibroblast growth factor receptor 1 | / | 0.454 | |
| 3sgx | 0FW | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.454 | |
| 3v8w | 0G2 | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.454 | |
| 4hyu | 1BK | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.454 | |
| 5bvw | 1N1 | Epithelial discoidin domain-containing receptor 1 | 2.7.10.1 | 0.454 | |
| 1u59 | STU | Tyrosine-protein kinase ZAP-70 | 2.7.10.2 | 0.453 | |
| 2exc | JNK | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.453 | |
| 3f69 | XDR | Serine/threonine-protein kinase PknB | 2.7.11.1 | 0.453 | |
| 2vwu | 7X1 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.452 | |
| 2xa4 | AZ5 | Tyrosine-protein kinase JAK2 | / | 0.452 | |
| 3cbl | STU | Tyrosine-protein kinase Fes/Fps | 2.7.10.2 | 0.452 | |
| 3gxl | QIG | TGF-beta receptor type-1 | 2.7.11.30 | 0.452 | |
| 3mwu | BK3 | Calmodulin-domain protein kinase 1, putative | / | 0.452 | |
| 3w2o | 03P | Epidermal growth factor receptor | 2.7.10.1 | 0.452 | |
| 4fst | HK4 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.452 | |
| 4ft7 | H3K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.452 | |
| 5aab | VGH | ALK tyrosine kinase receptor | 2.7.10.1 | 0.452 | |
| 1ie4 | T44 | Transthyretin | / | 0.451 | |
| 1oky | STU | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.451 | |
| 2qd9 | LGF | Mitogen-activated protein kinase 14 | / | 0.451 | |
| 3uib | SB2 | Putative mitogen-activated protein kinase | / | 0.451 | |
| 3zew | STU | Ephrin type-B receptor 4 | 2.7.10.1 | 0.451 | |
| 4cki | ADN | Proto-oncogene tyrosine-protein kinase receptor Ret | 2.7.10.1 | 0.451 | |
| 4fti | H7K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.451 | |
| 4ftl | H0K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.451 | |
| 1w84 | L12 | Mitogen-activated protein kinase 14 | / | 0.450 | |
| 3prf | FP3 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.450 | |
| 4cd0 | AWJ | ALK tyrosine kinase receptor | 2.7.10.1 | 0.450 | |
| 1xl2 | 189 | Gag-Pol polyprotein | 3.4.23.16 | 0.449 | |
| 2itu | ITQ | Epidermal growth factor receptor | 2.7.10.1 | 0.449 | |
| 2oh4 | GIG | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.449 | |
| 2p33 | J07 | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.449 | |
| 2wmq | ZYQ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.449 | |
| 3fmh | 533 | Mitogen-activated protein kinase 14 | / | 0.449 | |
| 3t11 | 3T1 | Gag-Pol polyprotein | 3.4.23.16 | 0.449 | |
| 4g31 | 0WH | Eukaryotic translation initiation factor 2-alpha kinase 3 | 2.7.11.1 | 0.449 | |
| 4mcv | 29K | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.449 | |
| 2bfy | H1N | Aurora kinase B-A | 2.7.11.1 | 0.448 | |
| 2i1m | 5CN | Macrophage colony-stimulating factor 1 receptor | 2.7.10.1 | 0.448 | |
| 2xf0 | 4UB | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.448 | |
| 3oom | 507 | Activin receptor type-1 | 2.7.11.30 | 0.448 | |
| 4a61 | ANP | Plasmid segregation protein ParM | / | 0.448 | |
| 4c3f | 7KW | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.448 | |
| 4jvf | 17X | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.448 | |
| 4nfn | 2KC | Tau-tubulin kinase 1 | 2.7.11.1 | 0.448 | |
| 5f0a | 1FB | cGMP-dependent protein kinase, putative | / | 0.448 | |
| 1qpj | STU | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.447 | |
| 2g2f | AGS | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.447 | |
| 2itx | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.447 | |
| 3a62 | STU | Ribosomal protein S6 kinase beta-1 | 2.7.11.1 | 0.447 | |
| 3ml8 | ML8 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.447 | |
| 3oro | AGS | Serine/threonine protein kinase | / | 0.447 | |
| 4fuy | EK2 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.447 | |
| 4g1w | G1W | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.447 | |
| 4jlc | SU6 | Serine/threonine-protein kinase TBK1 | 2.7.11.1 | 0.447 | |
| 1u54 | ACP | Activated CDC42 kinase 1 | / | 0.446 | |
| 2vgp | AD6 | Aurora kinase B-A | 2.7.11.1 | 0.446 | |
| 3itz | P66 | Mitogen-activated protein kinase 14 | / | 0.446 | |
| 4cd2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 4e4m | 0NH | Tyrosine-protein kinase JAK2 | / | 0.446 | |
| 4hys | 1BJ | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.446 | |
| 4k33 | ACP | Fibroblast growth factor receptor 3 | 2.7.10.1 | 0.446 | |
| 2cig | 1DG | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 3q3b | 55E | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.445 | |
| 4mvf | STU | Calcium-dependent protein kinase 2 | 2.7.11.1 | 0.445 | |
| 1pn3 | TYD | dTDP-epi-vancosaminyltransferase | 2.4.1.311 | 0.444 | |
| 2xvd | AS6 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.444 | |
| 2y7j | B49 | Phosphorylase b kinase gamma catalytic chain, liver/testis isoform | 2.7.11.19 | 0.444 | |
| 2yiq | YIQ | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.444 | |
| 3mpa | SB2 | Mitogen-activated protein kinase 14 | / | 0.444 | |
| 3vo3 | 0KF | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.444 | |
| 4eh6 | 0ON | Mitogen-activated protein kinase 14 | / | 0.444 | |
| 4g6n | EK0 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.444 | |
| 1k6c | MK1 | Gag-Pol polyprotein | 3.4.23.16 | 0.443 | |
| 2ycr | HCW | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.443 | |
| 3igo | ANP | Calmodulin-domain protein kinase 1, putative | / | 0.443 | |
| 3l08 | ZIG | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.443 | |
| 3lct | ADP | ALK tyrosine kinase receptor | 2.7.10.1 | 0.443 | |
| 3lj3 | WYE | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.443 | |
| 4kbc | 1QJ | Casein kinase I isoform delta | 2.7.11.1 | 0.443 | |
| 1pjk | ANP | Casein kinase II subunit alpha | 2.7.11.1 | 0.442 | |
| 3hdm | MMG | Serine/threonine-protein kinase Sgk1 | 2.7.11.1 | 0.442 | |
| 4d9t | 0JG | Ribosomal protein S6 kinase alpha-3 | 2.7.11.1 | 0.442 | |
| 4wq5 | ATP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.442 | |
| 4ydu | ADP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.442 | |
| 5ar4 | SB2 | Receptor-interacting serine/threonine-protein kinase 2 | 2.7.11.1 | 0.442 | |
| 5dr9 | SKE | Aurora kinase A | 2.7.11.1 | 0.442 | |
| 1uu8 | BI1 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.441 | |
| 2yit | YIT | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.441 | |
| 3ds6 | A17 | Mitogen-activated protein kinase 14 | / | 0.441 | |
| 4kba | 1QM | Casein kinase I isoform delta | 2.7.11.1 | 0.441 | |
| 5e8w | STU | TGF-beta receptor type-1 | 2.7.11.30 | 0.441 | |
| 4z35 | ON9 | Lysophosphatidic acid receptor 1 | / | 0.441 | |
| 1ppj | SMA | Cytochrome b | / | 0.440 | |
| 2cgu | 3A3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.440 | |
| 2e9o | A58 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.440 | |
| 2p55 | MRA | Dual specificity mitogen-activated protein kinase kinase 1 | 2.7.12.2 | 0.440 | |
| 2r7b | 253 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.440 | |
| 2ycs | NXP | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.440 | |
| 3dqw | AGS | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.440 | |
| 3ha8 | 5JZ | Mitogen-activated protein kinase 14 | / | 0.440 | |
| 3hp5 | 52P | Mitogen-activated protein kinase 14 | / | 0.440 | |
| 3jy0 | LYG | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.440 | |
| 3orz | BI4 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.440 | |
| 3v01 | 3V0 | Dual specificity mitogen-activated protein kinase kinase 1 | 2.7.12.2 | 0.440 | |
| 4acc | 7YG | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.440 | |
| 4agw | NG7 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.440 | |
| 4bdg | P3J | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.440 | |
| 4eoi | 1RO | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 | |
| 4ftn | 2HK | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.440 | |
| 4j54 | G52 | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
| 4wo5 | 324 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.440 | |
| 4wq4 | ATP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.440 |