Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
PDB ID | HET | Uniprot Name | EC Number |
---|---|---|---|
1l0l | FMX | Cytochrome b |
PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
---|---|---|---|---|---|
1l0l | FMX | Cytochrome b | / | 1.000 | |
2fyu | FDN | Cytochrome b | / | 0.526 | |
3vtd | TKD | Vitamin D3 receptor | / | 0.492 | |
3uvv | REA | Retinoic acid receptor RXR-alpha | / | 0.489 | |
1olm | VTQ | SEC14-like protein 2 | / | 0.486 | |
2p1u | 4TN | Retinoic acid receptor RXR-alpha | / | 0.485 | |
3vtc | TK3 | Vitamin D3 receptor | / | 0.485 | |
3eml | ZMA | Adenosine receptor A2a | / | 0.483 | |
1rdt | L79 | Retinoic acid receptor RXR-alpha | / | 0.482 | |
2bxq | IMN | Serum albumin | / | 0.482 | |
1fmj | RTL | Retinol dehydratase | / | 0.481 | |
1y60 | H4M | 5,6,7,8-tetrahydromethanopterin hydro-lyase | 4.2.1.147 | 0.481 | |
3vrw | YS5 | Vitamin D3 receptor | / | 0.481 | |
4ruj | VDX | Vitamin D3 receptor A | / | 0.480 | |
3kpz | ZNE | Vitamin D3 receptor | / | 0.479 | |
3v1m | HPK | 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase | 3.7.1.8 | 0.479 | |
4iar | ERM | 5-hydroxytryptamine receptor 1B | / | 0.479 | |
1kb9 | SMA | Cytochrome b | / | 0.478 | |
2pnu | ENM | Androgen receptor | / | 0.478 | |
1rkh | VD2 | Vitamin D3 receptor | / | 0.477 | |
2ouu | 35G | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.476 | |
3tgu | WF3 | Cytochrome b | / | 0.476 | |
1db1 | VDX | Vitamin D3 receptor | / | 0.474 | |
1txi | TX5 | Vitamin D3 receptor | / | 0.474 | |
2ydo | ADN | Adenosine receptor A2a | / | 0.473 | |
4g1z | 0VP | Vitamin D3 receptor A | / | 0.473 | |
1d3g | BRE | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.470 | |
1p8d | CO1 | Oxysterols receptor LXR-beta | / | 0.470 | |
3w5p | 4OA | Vitamin D3 receptor | / | 0.470 | |
4kla | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.470 | |
2op1 | 8PC | Enoyl-ACP reductase | / | 0.469 | |
2p1t | 3TN | Retinoic acid receptor RXR-alpha | / | 0.469 | |
2fpc | SCG | Strictosidine synthase | 4.3.3.2 | 0.468 | |
3e5a | VX6 | Aurora kinase A | 2.7.11.1 | 0.468 | |
3njo | PYV | Abscisic acid receptor PYR1 | / | 0.468 | |
3vt6 | 5YI | Vitamin D3 receptor | / | 0.468 | |
4ajm | 3A6 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.468 | |
4g1y | 0VO | Vitamin D3 receptor A | / | 0.468 | |
4q0a | 4OA | Vitamin D3 receptor A | / | 0.468 | |
1rk3 | VDX | Vitamin D3 receptor | / | 0.467 | |
1ybg | TAV | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.467 | |
2fm5 | M99 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.467 | |
2qd5 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.467 | |
4equ | G6I | Serine/threonine-protein kinase 10 | 2.7.11.1 | 0.467 | |
3sl6 | JN8 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.466 | |
1ezv | SMA | Cytochrome b | / | 0.465 | |
1fpq | SAM | Isoliquiritigenin 2'-O-methyltransferase | / | 0.465 | |
2hbh | XE4 | Vitamin D3 receptor A | / | 0.465 | |
3is9 | AC7 | Gag-Pol polyprotein | 2.7.7.49 | 0.465 | |
4fhh | 0U3 | Vitamin D3 receptor A | / | 0.465 | |
2qd4 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.464 | |
3vt5 | YI2 | Vitamin D3 receptor | / | 0.464 | |
4g20 | 484 | Vitamin D3 receptor A | / | 0.464 | |
4tzk | 641 | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.464 | |
2p1v | 5TN | Retinoic acid receptor RXR-alpha | / | 0.463 | |
3dr1 | C5D | Vitamin D3 receptor A | / | 0.462 | |
5k2a | ZMA | Adenosine receptor A2a | / | 0.462 | |
2xvv | 9DN | Serum albumin | / | 0.461 | |
3w5r | LOA | Vitamin D3 receptor | / | 0.461 | |
4dqu | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.461 | |
4mvh | 2F5 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.461 | |
5dq8 | FLF | Transcriptional enhancer factor TEF-4 | / | 0.461 | |
4ruo | BIV | Vitamin D3 receptor A | / | 0.460 | |
2acw | UPG | Glycosyltransferase | / | 0.459 | |
2hb7 | O1C | Vitamin D3 receptor | / | 0.459 | |
2qjy | SMA | Cytochrome b | / | 0.459 | |
2zla | VDB | Vitamin D3 receptor | / | 0.459 | |
3b9l | AZZ | Serum albumin | / | 0.459 | |
3tky | N7I | (Iso)eugenol O-methyltransferase | 2.1.1.146 | 0.459 | |
4iui | 1GQ | Estrogen receptor | / | 0.459 | |
1fds | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.458 | |
1x8l | OXR | Retinol dehydratase | / | 0.458 | |
2r0p | K2C | Putative FAD-monooxygenase | / | 0.458 | |
2xvw | 9NR | Serum albumin | / | 0.458 | |
3nxt | D2E | Dihydrofolate reductase | 1.5.1.3 | 0.458 | |
3wv9 | FEG | Hmd co-occurring protein HcgE | / | 0.458 | |
4dvi | 2IW | Tankyrase-1 | 2.4.2.30 | 0.458 | |
1fby | REA | Retinoic acid receptor RXR-alpha | / | 0.457 | |
1fml | RTL | Retinol dehydratase | / | 0.457 | |
1gpe | FAD | Glucose oxidase | 1.1.3.4 | 0.457 | |
1kkq | 471 | Peroxisome proliferator-activated receptor alpha | / | 0.457 | |
2p15 | EZT | Estrogen receptor | / | 0.457 | |
2ydv | NEC | Adenosine receptor A2a | / | 0.457 | |
3qtr | X36 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.457 | |
3vrv | YSD | Vitamin D3 receptor | / | 0.457 | |
3w0a | DS5 | Vitamin D3 receptor | / | 0.457 | |
4llk | MEW | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.457 | |
1fdw | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.456 | |
1mzn | BM6 | Retinoic acid receptor RXR-alpha | / | 0.456 | |
2acl | REA | Retinoic acid receptor RXR-alpha | / | 0.456 | |
2hw2 | RFP | Rifampin ADP-ribosyl transferase | / | 0.456 | |
3reo | EUG | (Iso)eugenol O-methyltransferase | 2.1.1.146 | 0.456 | |
3sl8 | JN7 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.456 | |
3t8x | T8X | T-cell surface glycoprotein CD1b | / | 0.456 | |
3v1s | 0LH | Strictosidine synthase | 4.3.3.2 | 0.456 | |
3vt4 | 5YI | Vitamin D3 receptor | / | 0.456 | |
4apu | A2K | Progesterone receptor | / | 0.456 | |
4ddl | 0JQ | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.456 | |
4mub | OAQ | Sulfotransferase oxamniquine resistance protein | / | 0.456 | |
5g53 | NEC | Adenosine receptor A2a | / | 0.456 | |
1s19 | MC9 | Vitamin D3 receptor | / | 0.455 | |
2zlc | VDX | Vitamin D3 receptor | / | 0.455 | |
3cxh | SMA | Cytochrome b | / | 0.455 | |
3ipq | 965 | Oxysterols receptor LXR-alpha | / | 0.455 | |
1dkf | BMS | Retinoic acid receptor alpha | / | 0.454 | |
1lco | PPY | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.454 | |
1mvc | BM6 | Retinoic acid receptor RXR-alpha | / | 0.454 | |
1o1v | TCH | Gastrotropin | / | 0.454 | |
1osv | CHC | Bile acid receptor | / | 0.454 | |
1xls | REA | Retinoic acid receptor RXR-alpha | / | 0.454 | |
2fzi | DH3 | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
2has | C3O | Vitamin D3 receptor | / | 0.454 | |
2hc4 | VDX | Vitamin D3 receptor A | / | 0.454 | |
2z7g | EH9 | Adenosine deaminase | 3.5.4.4 | 0.454 | |
3c3x | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.454 | |
3jyn | NDP | Quinone oxidoreductase | / | 0.454 | |
3l0l | HC3 | Nuclear receptor ROR-gamma | / | 0.454 | |
4jv8 | 1M1 | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.454 | |
4kfj | 1R0 | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
5uvi | ZMA | Adenosine receptor A2a | / | 0.454 | |
1x2h | LPA | Lipoate-protein ligase A | 6.3.1.20 | 0.453 | |
2gpv | OHT | Estrogen-related receptor gamma | / | 0.453 | |
2ibz | SMA | Cytochrome b | / | 0.453 | |
2nsd | 4PI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.453 | |
2zb4 | 5OP | Prostaglandin reductase 2 | 1.3.1.48 | 0.453 | |
3oap | REA | Retinoic acid receptor RXR-alpha | / | 0.453 | |
3w5e | NVW | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.453 | |
4ia1 | BIV | Vitamin D3 receptor A | / | 0.453 | |
3pwh | ZMA | Adenosine receptor A2a | / | 0.453 | |
1fm6 | 9CR | Retinoic acid receptor RXR-alpha | / | 0.452 | |
1ie8 | KH1 | Vitamin D3 receptor | / | 0.452 | |
3bfa | 9OD | Odorant binding protein ASP1 | / | 0.452 | |
3gkj | HC3 | Niemann-Pick C1 protein | / | 0.452 | |
3w0j | T08 | Vitamin D3 receptor | / | 0.452 | |
3w5t | LHP | Vitamin D3 receptor | / | 0.452 | |
4fcb | 0T7 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.452 | |
4ite | TEY | Vitamin D3 receptor | / | 0.452 | |
1rjk | VDZ | Vitamin D3 receptor | / | 0.451 | |
2ham | C33 | Vitamin D3 receptor | / | 0.451 | |
3cx5 | SMA | Cytochrome b | / | 0.451 | |
3sn7 | 540 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.451 | |
3vrt | YS2 | Vitamin D3 receptor | / | 0.451 | |
3vtb | TKA | Vitamin D3 receptor | / | 0.451 | |
1ndz | FR5 | Adenosine deaminase | 3.5.4.4 | 0.450 | |
2pog | WST | Estrogen receptor | / | 0.450 | |
3eta | 351 | Insulin receptor | 2.7.10.1 | 0.450 | |
3k9u | ACO | Spermidine N(1)-acetyltransferase | / | 0.450 | |
3p9t | TCL | Repressor | / | 0.450 | |
3qly | 55V | Uncharacterized protein | / | 0.450 | |
3qpo | PFR | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.450 | |
3s79 | ASD | Aromatase | 1.14.14.14 | 0.450 | |
4a84 | DXC | Major pollen allergen Bet v 1-A | / | 0.450 | |
4ajd | F04 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.450 | |
5iub | CLR | Adenosine receptor A2a | / | 0.450 | |
1l2j | ETC | Estrogen receptor beta | / | 0.449 | |
1uuo | BRF | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.449 | |
2ol4 | JPN | Enoyl-ACP reductase | / | 0.449 | |
2ovv | PFH | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.449 | |
2xls | FAD | Putative flavin-containing monooxygenase | / | 0.449 | |
3be2 | RAJ | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.449 | |
3bfb | 9OD | Pheromone-binding protein ASP1 | / | 0.449 | |
3fu9 | KIB | Laccase-1 | 1.10.3.2 | 0.449 | |
4ia3 | BIV | Vitamin D3 receptor A | / | 0.449 | |
4ia7 | BIV | Vitamin D3 receptor A | / | 0.449 | |
1khr | VIR | Streptogramin A acetyltransferase | 2.3.1 | 0.448 | |
1q9m | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.448 | |
1ygj | RMC | Pyridoxal kinase | 2.7.1.35 | 0.448 | |
2uxo | TAC | HTH-type transcriptional regulator TtgR | / | 0.448 | |
2uxp | CLM | HTH-type transcriptional regulator TtgR | / | 0.448 | |
2yiu | SMA | Cytochrome b | / | 0.448 | |
3cyz | 9OD | Pheromone-binding protein ASP1 | / | 0.448 | |
3g4i | D71 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.448 | |
3pqb | VGP | Putative oxidoreductase | / | 0.448 | |
3w5q | 3KL | Vitamin D3 receptor | / | 0.448 | |
4m8e | 29V | Retinoic acid receptor RXR-alpha | / | 0.448 | |
4xym | COA | Acyl-CoA synthetase (NDP forming) | / | 0.448 | |
1fvp | FMA | Non-fluorescent flavoprotein | / | 0.447 | |
1ly3 | COG | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
1ly4 | COQ | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
2acl | L05 | Oxysterols receptor LXR-alpha | / | 0.447 | |
2o12 | FMN | Chorismate synthase | / | 0.447 | |
2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.447 | |
2uxx | FAJ | Lysine-specific histone demethylase 1A | 1 | 0.447 | |
3elm | 24F | Collagenase 3 | 3.4.24 | 0.447 | |
3ipu | O40 | Oxysterols receptor LXR-alpha | / | 0.447 | |
4iaq | 2GM | 5-hydroxytryptamine receptor 1B | / | 0.447 | |
4tzt | 468 | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.447 | |
3qak | UKA | Adenosine receptor A2a | / | 0.447 | |
1gt5 | BZQ | Odorant-binding protein | / | 0.446 | |
1xp6 | AIU | Estrogen receptor | / | 0.446 | |
2o4j | VD4 | Vitamin D3 receptor | / | 0.446 | |
2p4i | MR9 | Angiopoietin-1 receptor | 2.7.10.1 | 0.446 | |
3fu8 | 3DM | Laccase-1 | 1.10.3.2 | 0.446 | |
3jsi | WTC | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.446 | |
3ntd | FAD | FAD-dependent pyridine nucleotide-disulphide oxidoreductase | / | 0.446 | |
4ead | 0NP | Thymidine phosphorylase | 2.4.2.4 | 0.446 | |
4okb | 198 | Androgen receptor | / | 0.446 | |
4z44 | FAD | Flavin-dependent tryptophan halogenase PrnA | 1.14.19.9 | 0.446 | |
5iu8 | 6DZ | Adenosine receptor A2a | / | 0.446 | |
5k2c | ZMA | Adenosine receptor A2a | / | 0.446 | |
5k2b | ZMA | Adenosine receptor A2a | / | 0.446 | |
3rfm | CFF | Adenosine receptor A2a | / | 0.446 | |
3w0y | DS4 | Vitamin D3 receptor | / | 0.445 | |
3w1w | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.445 | |
4cjx | 9L9 | C-1-tetrahydrofolate synthase, cytoplasmic, putative | / | 0.445 | |
4k4j | 1O8 | Retinoic acid receptor RXR-alpha | / | 0.445 | |
7cat | NDP | Catalase | 1.11.1.6 | 0.445 | |
5k2d | ZMA | Adenosine receptor A2a | / | 0.445 | |
3uzc | T4E | Adenosine receptor A2a | / | 0.445 | |
1crb | RTL | Retinol-binding protein 1 | / | 0.444 | |
1p44 | GEQ | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.444 | |
1rkg | VD1 | Vitamin D3 receptor | / | 0.444 | |
1sqq | OST | Cytochrome b | / | 0.444 | |
2xk8 | 5R1 | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.444 | |
2z3u | CRR | Cytochrome P450 | / | 0.444 | |
3a78 | 3EV | Vitamin D3 receptor | / | 0.444 | |
3g4g | D71 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.444 | |
3stv | 3HO | Methylketone synthase I | / | 0.444 | |
4ceq | QCH | Integrase | / | 0.444 | |
4i6f | 1C7 | Serine/threonine-protein kinase PLK2 | 2.7.11.21 | 0.444 | |
4iah | 1DX | Alr2278 protein | / | 0.444 | |
5doz | NDP | JamJ | / | 0.444 | |
2bl9 | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.443 | |
3g4k | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.443 | |
3qri | 919 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.443 | |
4bbx | LKF | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.443 | |
4g2h | 0VQ | Vitamin D3 receptor A | / | 0.443 | |
4m8h | R4M | Retinoic acid receptor RXR-alpha | / | 0.443 | |
5bt4 | 2LO | Bromodomain-containing protein 4 | / | 0.443 | |
1ci7 | UMP | Thymidylate synthase | 2.1.1.45 | 0.442 | |
1e1k | FAD | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.442 | |
1q1r | FAD | Putidaredoxin reductase | 1.18.1.5 | 0.442 | |
1xom | CIO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.442 | |
1zid | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.442 | |
2bxm | IMN | Serum albumin | / | 0.442 | |
2r5n | TPP | Transketolase 1 | / | 0.442 | |
3bej | MUF | Bile acid receptor | / | 0.442 | |
3bxx | QUE | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.442 | |
3mbg | FAD | FAD-linked sulfhydryl oxidase ALR | 1.8.3.2 | 0.442 | |
3vt3 | VDX | Vitamin D3 receptor | / | 0.442 | |
4fhi | 0S4 | Vitamin D3 receptor A | / | 0.442 | |
4g21 | 0VP | Vitamin D3 receptor A | / | 0.442 | |
5jtb | ZMA | Adenosine receptor A2a | / | 0.442 | |
1fm9 | 9CR | Retinoic acid receptor RXR-alpha | / | 0.441 | |
1t7o | 152 | Carnitine O-acetyltransferase | 2.3.1.7 | 0.441 | |
1xu9 | CPS | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.441 | |
2pnc | CLU | Primary amine oxidase, liver isozyme | / | 0.441 | |
3aba | FLI | Cytochrome P450 | / | 0.441 | |
3w0c | 6DS | Vitamin D3 receptor | / | 0.441 | |
4fhd | 0TT | Spore photoproduct lyase | / | 0.441 | |
4o70 | 1QK | Bromodomain-containing protein 4 | / | 0.441 | |
4rup | H97 | Vitamin D3 receptor A | / | 0.441 | |
1juj | LYA | Thymidylate synthase | 2.1.1.45 | 0.440 | |
1kyo | SMA | Cytochrome b | / | 0.440 | |
2a0w | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.440 | |
2rl5 | 2RL | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.440 | |
2wey | EV1 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.440 | |
2zl9 | VDA | Vitamin D3 receptor | / | 0.440 | |
3cz0 | 9OD | Pheromone-binding protein ASP1 | / | 0.440 | |
3dd1 | 25D | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.440 | |
3nta | FAD | FAD-dependent pyridine nucleotide-disulphide oxidoreductase | / | 0.440 | |
3o57 | ZG2 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.440 | |
4eiy | ZMA | Adenosine receptor A2a | / | 0.440 | |
4phl | PIL | Phosphodiesterase | / | 0.440 | |
5iua | 6DX | Adenosine receptor A2a | / | 0.440 |