scPDB - Distribution of Binding site Similarity values of 4odo entry / Site 2

Distribution of Binding site similarity measured by Shaper

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Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
4odo	FK5	Peptidyl-prolyl cis-trans isomerase

Complex with similar binding sites

PDB ID	HET	Uniprot Name	EC Number	Binding Site Similarity
4odo	FK5	Peptidyl-prolyl cis-trans isomerase	/	1.000
1xdd	AAY	Integrin alpha-L	/	0.485
1dhi	MTX	Dihydrofolate reductase	1.5.1.3	0.480
4xwt	U5P	Ribonuclease J	/	0.478
3vqs	JT1	Genome polyprotein	/	0.475
4xsv	C5P	Ethanolamine-phosphate cytidylyltransferase	2.7.7.14	0.471
4f4d	CHD	Ferrochelatase, mitochondrial	4.99.1.1	0.470
2uxp	CLM	HTH-type transcriptional regulator TtgR	/	0.468
3czr	3CZ	Corticosteroid 11-beta-dehydrogenase isozyme 1	1.1.1.146	0.467
4lxj	LAN	Lanosterol 14-alpha demethylase	1.14.13.70	0.466
2cf6	NAP	Cinnamyl alcohol dehydrogenase 5	1.1.1.195	0.465
4ict	1ED	Mycocyclosin synthase	1.14.21.9	0.465
4m83	ERY	Oleandomycin glycosyltransferase	2.4.1	0.465
4iar	ERM	5-hydroxytryptamine receptor 1B	/	0.464
4ipw	1G7	Mycocyclosin synthase	1.14.21.9	0.464
1h69	ARH	NAD(P)H dehydrogenase [quinone] 1	1.6.5.2	0.463
3u8h	BHP	Phospholipase A2, membrane associated	/	0.463
2g1r	3IG	Renin	3.4.23.15	0.462
4g7g	VFV	Lanosterol 14-alpha-demethylase	/	0.462
4iah	1DX	Alr2278 protein	/	0.462
2x7h	PFN	Prostaglandin reductase 3	1	0.461
3ssn	MVI	Mycinamicin VI 2''-O-methyltransferase	/	0.461
4q0k	GA3	Phytohormone-binding protein	/	0.460
3s79	ASD	Aromatase	1.14.14.14	0.458
4hy6	FJ1	Heat shock protein HSP 90-alpha	/	0.457
4l8u	9AZ	Serum albumin	/	0.457
5eai	FAD	NAD(P)H dehydrogenase [quinone] 1	1.6.5.2	0.457
1w6h	TIT	Plasmepsin-2	3.4.23.39	0.456
2xc3	RT8	Steroid C26-monooxygenase	1.14.13.141	0.456
4gl4	NAI	Alcohol dehydrogenase class-3	/	0.456
2po7	CHD	Ferrochelatase, mitochondrial	4.99.1.1	0.455
2vbd	V10	Isopenicillin N synthase	1.21.3.1	0.454
3h3q	H13	Collagen type IV alpha-3-binding protein	/	0.454
3ibd	CPZ	Cytochrome P450 2B6	1.14.13	0.453
3vt8	YI3	Vitamin D3 receptor	/	0.453
4a30	QMI	Glycylpeptide N-tetradecanoyltransferase	/	0.453
1ay0	TPP	Transketolase 1	2.2.1.1	0.452
1psa	0ZL	Pepsin A	3.4.23.1	0.452
1uye	PU9	Heat shock protein HSP 90-alpha	/	0.452
1x8l	OXR	Retinol dehydratase	/	0.452
3sf6	FDA	Glutaryl-CoA dehydrogenase	/	0.452
1dyj	DDF	Dihydrofolate reductase	1.5.1.3	0.451
1kbo	FAD	NAD(P)H dehydrogenase [quinone] 1	1.6.5.2	0.451
1tdr	MTX	Dihydrofolate reductase	1.5.1.3	0.451
2hrc	CHD	Ferrochelatase, mitochondrial	4.99.1.1	0.451
3h0b	B35	Beta-secretase 1	3.4.23.46	0.451
1axw	MTX	Thymidylate synthase	/	0.450
4l9q	9TP	Serum albumin	/	0.450
5hs1	VOR	Lanosterol 14-alpha demethylase	/	0.450
1bk0	ACV	Isopenicillin N synthase	1.21.3.1	0.449
1j3k	WRA	Bifunctional dihydrofolate reductase-thymidylate synthase	1.5.1.3	0.449
3t8x	T8X	T-cell surface glycoprotein CD1b	/	0.449
3zei	AWH	O-acetylserine sulfhydrylase	/	0.449
4a6n	FAD	TetX family tetracycline inactivation enzyme	/	0.449
4bfz	ZVZ	Pantothenate kinase	2.7.1.33	0.449
4pnm	NU1	Tankyrase-2	2.4.2.30	0.449
1rb3	MTX	Dihydrofolate reductase	1.5.1.3	0.448
2uxo	TAC	HTH-type transcriptional regulator TtgR	/	0.448
3oqf	S51	Renin	3.4.23.15	0.448
4iae	1DX	Alr2278 protein	/	0.448
4ktl	1CQ	Cytochrome P450	/	0.448
1h66	FAD	NAD(P)H dehydrogenase [quinone] 1	1.6.5.2	0.447
2w0d	CGS	Macrophage metalloelastase	3.4.24.65	0.447
3g5h	YTT	Mycocyclosin synthase	1.14.21.9	0.447
3qe2	FMN	NADPH--cytochrome P450 reductase	/	0.447
3s1d	ZIR	Cytokinin dehydrogenase 1	1.5.99.12	0.447
3zky	WT4	Isopenicillin N synthase	1.21.3.1	0.447
3zuy	TCH	Transporter	/	0.447
4g3j	VNT	Lanosterol 14-alpha-demethylase	/	0.447
5a4k	FAD	NAD(P)H dehydrogenase [quinone] 1	1.6.5.2	0.447
1hb1	OCV	Isopenicillin N synthase	1.21.3.1	0.446
4b1r	ITC	Tetracycline repressor protein class D	/	0.446
4b2g	V1N	Uncharacterized protein	/	0.446
4dym	IYZ	Activin receptor type-1	2.7.11.30	0.446
4kby	C2E	Stimulator of interferon genes protein	/	0.446
1drb	MTX	Dihydrofolate reductase	1.5.1.3	0.445
1qjf	ACS	Isopenicillin N synthase	1.21.3.1	0.445
2zba	ZBA	Trichothecene 3-O-acetyltransferase	/	0.445
3vt7	VDX	Vitamin D3 receptor	/	0.445
1gg5	FAD	NAD(P)H dehydrogenase [quinone] 1	1.6.5.2	0.444
1rb2	FOL	Dihydrofolate reductase	1.5.1.3	0.444
2g24	7IG	Renin	3.4.23.15	0.444
3drc	MTX	Dihydrofolate reductase	1.5.1.3	0.444
3own	3OW	Renin	3.4.23.15	0.444
3sgv	2BJ	Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)	2.5.1.31	0.444
4ly9	1YY	Glucokinase regulatory protein	/	0.444
4n1g	CEI	Obelin	/	0.444
1fml	RTL	Retinol dehydratase	/	0.443
1h69	FAD	NAD(P)H dehydrogenase [quinone] 1	1.6.5.2	0.443
1m13	HYF	Nuclear receptor subfamily 1 group I member 2	/	0.443
1zx1	CB1	Ribosyldihydronicotinamide dehydrogenase [quinone]	/	0.443
3l6j	Z90	Alr2278 protein	/	0.443
4bfv	ZVV	Pantothenate kinase	2.7.1.33	0.443
4i8v	BHF	Cytochrome P450 1A1	1.14.14.1	0.443
4ia3	BIV	Vitamin D3 receptor A	/	0.443
4ryv	ZEA	Protein LlR18A	/	0.443
4yao	FMN	NADPH--cytochrome P450 reductase	/	0.443
1c7o	PPG	Hemolysin	/	0.442
1kbq	FAD	NAD(P)H dehydrogenase [quinone] 1	1.6.5.2	0.442
1msm	JE2	Gag-Pol polyprotein	3.4.23.16	0.442
1nzd	UPG	DNA beta-glucosyltransferase	/	0.442
2huq	SAH	Diphthine synthase	/	0.442
2iyf	ERY	Oleandomycin glycosyltransferase	2.4.1	0.442
2w0b	CMW	Lanosterol 14-alpha demethylase	1.14.13.70	0.442
2yne	YNE	Glycylpeptide N-tetradecanoyltransferase	/	0.442
3jsx	CC2	NAD(P)H dehydrogenase [quinone] 1	1.6.5.2	0.442
3p2e	SAH	16S rRNA (adenine(1408)-N(1))-methyltransferase	2.1.1.180	0.442
3p3z	P3Z	Putative cytochrome P450	/	0.442
4a2z	VIQ	Glycylpeptide N-tetradecanoyltransferase	/	0.442
1d4a	FAD	NAD(P)H dehydrogenase [quinone] 1	1.6.5.2	0.441
1ndz	FR5	Adenosine deaminase	3.5.4.4	0.441
2op9	WR1	Orf1ab polyprotein	/	0.441
2pnj	CHD	Ferrochelatase, mitochondrial	4.99.1.1	0.441
3zc3	NAP	Ferredoxin--NADP reductase	1.18.1.2	0.441
4b13	X25	Glycylpeptide N-tetradecanoyltransferase	/	0.441
4bb6	HD1	Corticosteroid 11-beta-dehydrogenase isozyme 1	1.1.1.146	0.441
4mv8	ACP	Biotin carboxylase	6.3.4.14	0.441
1fm4	DXC	Major pollen allergen Bet v 1-L	/	0.440
1ppj	ANY	Cytochrome b	/	0.440
1uym	PU3	Heat shock protein HSP 90-beta	/	0.440
2ij7	TPF	Mycocyclosin synthase	1.14.21.9	0.440
2j14	GNI	Peroxisome proliferator-activated receptor delta	/	0.440
3oht	1N1	Mitogen-activated protein kinase	/	0.440
4ips	1G4	Mycocyclosin synthase	1.14.21.9	0.440
4yau	FAD	NADPH--cytochrome P450 reductase	/	0.440