sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4du8 | 2P0 | Mevalonate diphosphate decarboxylase |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 4du8 | 2P0 | Mevalonate diphosphate decarboxylase | / | 1.000 | |
| 4dpu | AGS | Mevalonate diphosphate decarboxylase | / | 0.569 | |
| 3qt6 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.557 | |
| 4dpy | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.533 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.484 | |
| 4dpt | AGS | Mevalonate diphosphate decarboxylase | / | 0.483 | |
| 1vbi | NAD | Malate/L-lactate dehydrogenase family protein | / | 0.481 | |
| 3k3e | PDB | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.481 | |
| 3tjz | GNP | ADP-ribosylation factor 1 | / | 0.479 | |
| 2q85 | 973 | UDP-N-acetylenolpyruvoylglucosamine reductase | 1.3.1.98 | 0.478 | |
| 4jld | ADP | Adenylate kinase | / | 0.478 | |
| 1tqf | 32P | Beta-secretase 1 | 3.4.23.46 | 0.477 | |
| 4eak | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.477 | |
| 3c1y | 2BA | DNA integrity scanning protein DisA | / | 0.476 | |
| 4amb | DUD | Putative glycosyl transferase | / | 0.476 | |
| 4e90 | 7RG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.474 | |
| 1m8k | NAD | Nicotinamide-nucleotide adenylyltransferase | 2.7.7.1 | 0.473 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.472 | |
| 2rlc | CHD | Choloylglycine hydrolase | 3.5.1.24 | 0.472 | |
| 4zju | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.472 | |
| 3uic | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.471 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.470 | |
| 3c21 | 2BA | DNA integrity scanning protein DisA | / | 0.470 | |
| 4q73 | FAD | Bifunctional protein PutA | / | 0.470 | |
| 4f4d | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.469 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.468 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.468 | |
| 3h3q | H13 | Collagen type IV alpha-3-binding protein | / | 0.468 | |
| 4g7g | VFV | Lanosterol 14-alpha-demethylase | / | 0.468 | |
| 4xgu | ADP | Putative pachytene checkpoint protein 2 | / | 0.468 | |
| 2o1s | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.467 | |
| 1d4a | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.466 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.466 | |
| 4gdy | 0X1 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.466 | |
| 4xr9 | NAD | CalS8 | / | 0.466 | |
| 2xtn | GTP | GTPase IMAP family member 2 | / | 0.465 | |
| 3zw9 | NAD | Peroxisomal bifunctional enzyme | 1.1.1.35 | 0.464 | |
| 4cvm | ANP | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase | / | 0.464 | |
| 4nd2 | A3D | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.464 | |
| 1j49 | NAD | D-lactate dehydrogenase | 1.1.1.28 | 0.462 | |
| 2abb | FMN | Pentaerythritol tetranitrate reductase | / | 0.462 | |
| 3gqv | NAP | Enoyl reductase LovC | 1 | 0.462 | |
| 4jnk | NAI | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.462 | |
| 4o1m | NAD | Enoyl-acyl carrier reductase | / | 0.461 | |
| 2ktd | PUC | Prostaglandin-H2 D-isomerase | 5.3.99.2 | 0.460 | |
| 2oor | NAD | NAD(P) transhydrogenase subunit alpha part 1 | 1.6.1.2 | 0.460 | |
| 4e5y | NDP | GDP-L-fucose synthase | 1.1.1.271 | 0.460 | |
| 4q72 | FAD | Bifunctional protein PutA | / | 0.460 | |
| 2g1n | 1IG | Renin | 3.4.23.15 | 0.459 | |
| 2gv8 | NDP | Thiol-specific monooxygenase | 1.14.13 | 0.459 | |
| 2hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.459 | |
| 3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.459 | |
| 3h86 | AP5 | Adenylate kinase | / | 0.459 | |
| 3lfm | 3DT | Alpha-ketoglutarate-dependent dioxygenase FTO | / | 0.459 | |
| 3slk | NDP | Polyketide synthase extender module 2 | / | 0.459 | |
| 4nie | NBH | Nuclear receptor ROR-gamma | / | 0.459 | |
| 4wdf | A2P | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.459 | |
| 1hdc | CBO | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.458 | |
| 2dte | NAI | Glucose 1-dehydrogenase related protein | / | 0.458 | |
| 2q1u | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.458 | |
| 3hk1 | B64 | Fatty acid-binding protein, adipocyte | / | 0.458 | |
| 5a4k | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.458 | |
| 2d29 | FAD | Acyl-CoA dehydrogenase | / | 0.457 | |
| 3b6z | CO7 | Enoyl reductase LovC | 1 | 0.457 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.457 | |
| 4rvf | TYD | D-mycarose 3-C-methyltransferase | / | 0.457 | |
| 4xsv | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.457 | |
| 2fsv | NAD | NAD(P) transhydrogenase subunit alpha part 1 | 1.6.1.2 | 0.456 | |
| 2vke | TAC | Tetracycline repressor protein class D | / | 0.456 | |
| 3a1c | ACP | Probable copper-exporting P-type ATPase A | 3.6.3.54 | 0.456 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.456 | |
| 4fry | NAD | Putative signal-transduction protein with CBS domains | / | 0.456 | |
| 1u2g | APR | NAD(P) transhydrogenase subunit alpha part 1 | 1.6.1.2 | 0.455 | |
| 3jun | AJD | Phenazine biosynthesis protein A/B | / | 0.455 | |
| 4fw8 | NAI | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.455 | |
| 4jlo | ADP | Adenylate kinase | / | 0.455 | |
| 1h51 | FMN | Pentaerythritol tetranitrate reductase | / | 0.454 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.454 | |
| 1uzw | CDH | Isopenicillin N synthase | 1.21.3.1 | 0.454 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.454 | |
| 2ztv | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.454 | |
| 3to6 | LYS_CMC | Histone acetyltransferase ESA1 | / | 0.454 | |
| 4ge9 | 0L0 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.454 | |
| 4xye | NAD | Formate dehydrogenase | / | 0.454 | |
| 5eai | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.454 | |
| 1h73 | ANP | Homoserine kinase | 2.7.1.39 | 0.453 | |
| 1kfb | IGP | Tryptophan synthase alpha chain | / | 0.453 | |
| 1xe6 | 5FP | Plasmepsin-2 | 3.4.23.39 | 0.453 | |
| 1yb5 | NAP | Quinone oxidoreductase | 1.6.5.5 | 0.453 | |
| 2a92 | NAI | L-lactate dehydrogenase | / | 0.453 | |
| 4m83 | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.453 | |
| 1t2c | NAI | L-lactate dehydrogenase | 1.1.1.27 | 0.452 | |
| 2yxu | ATP | Pyridoxal kinase | 2.7.1.35 | 0.452 | |
| 3phi | NDP | Shikimate dehydrogenase (NADP(+)) | / | 0.452 | |
| 4fqs | LYA | Thymidylate synthase ThyA | / | 0.452 | |
| 4xiw | AZM | Carbonic anhydrase, alpha type | / | 0.452 | |
| 5ein | NAP | [LysW]-L-2-aminoadipate 6-phosphate reductase | / | 0.452 | |
| 1beu | IPL | Tryptophan synthase alpha chain | / | 0.451 | |
| 2bi4 | NAD | Lactaldehyde reductase | 1.1.1.77 | 0.451 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.451 | |
| 2npa | MMB | Peroxisome proliferator-activated receptor alpha | / | 0.451 | |
| 3m1v | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.451 | |
| 3m1v | COM | Methyl-coenzyme M reductase I subunit beta | 2.8.4.1 | 0.451 | |
| 3nxx | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 4hwk | NAP | Sepiapterin reductase | 1.1.1.153 | 0.451 | |
| 4jnk | ZHK | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.451 | |
| 1b16 | NAQ | Alcohol dehydrogenase | 1.1.1.1 | 0.450 | |
| 1gve | NAP | Aflatoxin B1 aldehyde reductase member 3 | 1 | 0.450 | |
| 1hdo | NAP | Flavin reductase (NADPH) | / | 0.450 | |
| 1xdp | ATP | Polyphosphate kinase | / | 0.450 | |
| 2c1b | CQP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.450 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.450 | |
| 3b2s | B2S | Trichothecene 3-O-acetyltransferase | / | 0.450 | |
| 3b70 | NAP | Enoyl reductase LovC | 1 | 0.450 | |
| 3gw9 | VNI | Lanosterol 14-alpha-demethylase | / | 0.450 | |
| 3o03 | NAP | Dehydrogenase with different specificities (Related to short-chain alcohol dehydrogenase) | / | 0.450 | |
| 3tqa | NDP | Dihydrofolate reductase | / | 0.450 | |
| 4b68 | FAD | L-ornithine N(5)-monooxygenase | / | 0.450 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.450 | |
| 4dh6 | 0KN | Beta-secretase 1 | 3.4.23.46 | 0.450 | |
| 4hp8 | NAP | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.450 | |
| 4yvz | 3AT | DNA integrity scanning protein DisA | / | 0.450 | |
| 4z3d | NDP | Carbonyl reductase [NADPH] 1 | 1.1.1.184 | 0.450 | |
| 1dr2 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 1h2b | NAJ | NAD-dependent alcohol dehydrogenase | / | 0.449 | |
| 1m13 | HYF | Nuclear receptor subfamily 1 group I member 2 | / | 0.449 | |
| 1p0h | ACO | Mycothiol acetyltransferase | 2.3.1.189 | 0.449 | |
| 1ty9 | FMN | Phenazine biosynthesis protein PhzG | 1.4 | 0.449 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.449 | |
| 2wns | OMP | Uridine 5'-monophosphate synthase | 2.4.2.10 | 0.449 | |
| 4oh4 | ANP | Protein BRASSINOSTEROID INSENSITIVE 1 | 2.7.10.1 | 0.449 | |
| 1eq2 | NAP | ADP-L-glycero-D-manno-heptose-6-epimerase | / | 0.448 | |
| 1h63 | FMN | Pentaerythritol tetranitrate reductase | / | 0.448 | |
| 1kkq | 471 | Peroxisome proliferator-activated receptor alpha | / | 0.448 | |
| 1zio | AP5 | Adenylate kinase | / | 0.448 | |
| 2a1h | GBN | Branched-chain-amino-acid aminotransferase, mitochondrial | 2.6.1.42 | 0.448 | |
| 2g1s | 4IG | Renin | 3.4.23.15 | 0.448 | |
| 3bhi | NAP | Carbonyl reductase [NADPH] 1 | 1.1.1.184 | 0.448 | |
| 4ipw | 1G7 | Mycocyclosin synthase | 1.14.21.9 | 0.448 | |
| 4m49 | 22Y | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.448 | |
| 1ma0 | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.447 | |
| 1nup | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.447 | |
| 1pqc | 444 | Oxysterols receptor LXR-beta | / | 0.447 | |
| 1xe5 | 5FE | Plasmepsin-2 | 3.4.23.39 | 0.447 | |
| 1xkd | NAP | Isocitrate dehydrogenase [NADP] | / | 0.447 | |
| 2cmj | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.447 | |
| 2emu | SAH | Diphthine synthase | / | 0.447 | |
| 2i7p | ACO | Pantothenate kinase 3 | 2.7.1.33 | 0.447 | |
| 2jcx | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | / | 0.447 | |
| 2jkv | NAP | 6-phosphogluconate dehydrogenase, decarboxylating | 1.1.1.44 | 0.447 | |
| 2oap | ANP | Type II secretion system protein (GspE-2) | / | 0.447 | |
| 2qo5 | CHD | Fatty acid-binding protein 10-A, liver basic | / | 0.447 | |
| 3dl0 | AP5 | Adenylate kinase | / | 0.447 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.447 | |
| 4g3j | VNT | Lanosterol 14-alpha-demethylase | / | 0.447 | |
| 5irn | ADP | Nucleotide binding oligomerization domain containing 2 | / | 0.447 | |
| 1mj9 | COA | Histone acetyltransferase ESA1 | / | 0.446 | |
| 1qoq | IGP | Tryptophan synthase alpha chain | / | 0.446 | |
| 1zrq | FAD | 5,10-methylenetetrahydrofolate reductase | 1.5.1.20 | 0.446 | |
| 2ft9 | CHD | Fatty acid-binding protein 2, liver | / | 0.446 | |
| 2g1r | 3IG | Renin | 3.4.23.15 | 0.446 | |
| 2uxo | TAC | HTH-type transcriptional regulator TtgR | / | 0.446 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.446 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.446 | |
| 4gyz | D5M | Tyrosyl-DNA phosphodiesterase 2 | 3.1.4 | 0.446 | |
| 4i1i | NAD | Malate dehydrogenase | / | 0.446 | |
| 1adf | TAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.445 | |
| 1qlh | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.445 | |
| 1yqd | NAP | Sinapyl alcohol dehydrogenase | / | 0.445 | |
| 2ahr | NAP | Pyrroline-5-carboxylate reductase | / | 0.445 | |
| 2f7x | 4EA | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.445 | |
| 2fto | CB3 | Thymidylate synthase | / | 0.445 | |
| 2wqp | WQP | Polysialic acid capsule biosynthesis protein SiaC | / | 0.445 | |
| 2y0m | ACO | Histone acetyltransferase KAT8 | / | 0.445 | |
| 3axk | NDP | Ribulose bisphosphate carboxylase large chain | 4.1.1.39 | 0.445 | |
| 3d8v | UD1 | Bifunctional protein GlmU | / | 0.445 | |
| 3p74 | FMN | Pentaerythritol tetranitrate reductase | / | 0.445 | |
| 3td7 | FAD | Probable FAD-linked sulfhydryl oxidase R596 | 1.8.3.2 | 0.445 | |
| 4a6n | FAD | TetX family tetracycline inactivation enzyme | / | 0.445 | |
| 4cdm | FO1 | Deoxyribodipyrimidine photolyase | / | 0.445 | |
| 4jky | ADP | Adenylate kinase | / | 0.445 | |
| 4kto | FAD | Putative isovaleryl-CoA dehydrogenase protein | / | 0.445 | |
| 5b1y | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.445 | |
| 1mja | COA | Histone acetyltransferase ESA1 | / | 0.444 | |
| 1mjb | ACO | Histone acetyltransferase ESA1 | / | 0.444 | |
| 1rfu | ADP | Pyridoxal kinase | 2.7.1.35 | 0.444 | |
| 2a94 | AP0 | L-lactate dehydrogenase | 1.1.1.27 | 0.444 | |
| 2rcy | NAP | Pyrroline-5-carboxylate reductase | / | 0.444 | |
| 2zat | NAP | Dehydrogenase/reductase SDR family member 4 | 1.1.1.184 | 0.444 | |
| 3atz | FMN | Prostaglandin F2a synthase | / | 0.444 | |
| 3c0g | 3AM | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.444 | |
| 3d4p | NAD | L-lactate dehydrogenase 1 | 1.1.1.27 | 0.444 | |
| 3g5h | YTT | Mycocyclosin synthase | 1.14.21.9 | 0.444 | |
| 3m6i | NAD | L-arabinitol 4-dehydrogenase | 1.1.1.12 | 0.444 | |
| 3tr0 | 5GP | Guanylate kinase | / | 0.444 | |
| 3tza | TZG | Glutamate receptor 2 | / | 0.444 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.444 | |
| 4ewn | 0VR | Imidazole glycerol phosphate synthase subunit HisF | 4.1.3 | 0.444 | |
| 4trn | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.444 | |
| 1njf | ADP | DNA polymerase III subunit tau | 2.7.7.7 | 0.443 | |
| 2aqi | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.443 | |
| 2fn7 | NAD | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.443 | |
| 2i4q | UA4 | Renin | 3.4.23.15 | 0.443 | |
| 2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.443 | |
| 2q1s | NAI | Putative nucleotide sugar epimerase/ dehydratase | / | 0.443 | |
| 2x7h | PFN | Prostaglandin reductase 3 | 1 | 0.443 | |
| 3bv2 | P38 | Mitogen-activated protein kinase 14 | / | 0.443 | |
| 3dv3 | MEK | Dual specificity mitogen-activated protein kinase kinase 1 | 2.7.12.2 | 0.443 | |
| 3gwf | NAP | Cyclohexanone monooxygenase | / | 0.443 | |
| 3haz | FAD | Bifunctional protein PutA | / | 0.443 | |
| 3ijd | C2F | Methylenetetrahydrofolate reductase | / | 0.443 | |
| 3k3h | BYE | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.443 | |
| 4a80 | 2AN | Major pollen allergen Bet v 1-A | / | 0.443 | |
| 4a8v | 2AN | Major pollen allergen Bet v 1-J | / | 0.443 | |
| 4an4 | DUD | Putative glycosyl transferase | / | 0.443 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.443 | |
| 4k6f | NAP | Putative Acetoacetyl-CoA reductase | / | 0.443 | |
| 5hws | NAP | 2-dehydropantoate 2-reductase | / | 0.443 | |
| 1ju2 | FAD | (R)-mandelonitrile lyase 2 | 4.1.2.10 | 0.442 | |
| 1q12 | ATP | Maltose/maltodextrin import ATP-binding protein MalK | / | 0.442 | |
| 1thy | UMP | Thymidylate synthase | / | 0.442 | |
| 2abj | CBC | Branched-chain-amino-acid aminotransferase, cytosolic | 2.6.1.42 | 0.442 | |
| 2ien | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.442 | |
| 2ql6 | ADP | Nicotinamide riboside kinase 1 | / | 0.442 | |
| 2rh9 | IGP | Tryptophan synthase alpha chain | / | 0.442 | |
| 3a3g | DLZ | Lumazine protein | / | 0.442 | |
| 3c35 | KAI | Glutamate receptor ionotropic, kainate 1 | / | 0.442 | |
| 3iaa | TYD | CalG2 | / | 0.442 | |
| 3nsh | 957 | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 3qv1 | NAD | Glyceraldehyde-3-phosphate dehydrogenase GAPA1, chloroplastic | 1.2.1.13 | 0.442 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.442 | |
| 4dfg | 0JV | Gag-Pol polyprotein | 3.4.23.16 | 0.442 | |
| 4i0i | 957 | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 4nd3 | NAD | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.442 | |
| 1dg8 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 1dir | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.441 | |
| 1i59 | ANP | Chemotaxis protein CheA | 2.7.13.3 | 0.441 | |
| 1juv | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 1kp3 | ATP | Argininosuccinate synthase | 6.3.4.5 | 0.441 | |
| 2eeq | SAH | Diphthine synthase | / | 0.441 | |
| 2g20 | L1A | Renin | 3.4.23.15 | 0.441 | |
| 2i7n | ACO | Pantothenate kinase 1 | 2.7.1.33 | 0.441 | |
| 2owu | SAH | Diphthine synthase | / | 0.441 | |
| 2x0i | NAI | Malate dehydrogenase | / | 0.441 | |
| 2x8h | FAD | Thioredoxin glutathione reductase | / | 0.441 | |
| 3em0 | CHD | Fatty acid-binding protein 6, ileal (gastrotropin) | / | 0.441 | |
| 3geg | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.441 | |
| 3qls | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 4eyw | L0R | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.441 | |
| 4jb1 | NAP | UDP-N-acetylenolpyruvoylglucosamine reductase | / | 0.441 | |
| 4kzo | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.441 | |
| 4yxm | 2BA | DNA integrity scanning protein DisA | / | 0.441 | |
| 5ao1 | DG3 | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.441 | |
| 1dxo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.440 | |
| 1ha3 | MAU | Elongation factor Tu-A | / | 0.440 | |
| 1hku | NAD | C-terminal-binding protein 1 | 1.1.1 | 0.440 | |
| 1ib6 | NAD | Malate dehydrogenase | / | 0.440 | |
| 2avv | MK1 | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
| 2bu9 | HFV | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
| 2g22 | 6IG | Renin | 3.4.23.15 | 0.440 | |
| 2ifa | FMN | Uncharacterized protein | / | 0.440 | |
| 2w3b | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 2x06 | NAD | L-sulfolactate dehydrogenase | / | 0.440 | |
| 2y60 | M8F | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
| 2y8l | ADP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.440 | |
| 2ztm | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.440 | |
| 3d84 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 3ibq | ATP | Pyridoxal kinase | / | 0.440 | |
| 3jun | AKD | Phenazine biosynthesis protein A/B | / | 0.440 | |
| 3mpj | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.440 | |
| 3qe0 | GDP | Guanine nucleotide-binding protein G(i) subunit alpha-1 | / | 0.440 | |
| 3zbz | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.440 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
| 4a99 | FAD | TetX family tetracycline inactivation enzyme | / | 0.440 | |
| 4dc0 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.440 |