Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3a4p | DFQ | Hepatocyte growth factor receptor | 2.7.10.1 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 3a4p | DFQ | Hepatocyte growth factor receptor | 2.7.10.1 | 1.000 | |
| 4gg7 | 0J8 | Hepatocyte growth factor receptor | 2.7.10.1 | 0.602 | |
| 2wgj | VGH | Hepatocyte growth factor receptor | 2.7.10.1 | 0.559 | |
| 4lm5 | Q17 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.550 | |
| 3zze | 6XP | Hepatocyte growth factor receptor | 2.7.10.1 | 0.549 | |
| 4gg5 | 0J3 | Hepatocyte growth factor receptor | 2.7.10.1 | 0.542 | |
| 1xjd | STU | Protein kinase C theta type | 2.7.11.13 | 0.538 | |
| 4ap7 | F47 | Hepatocyte growth factor receptor | 2.7.10.1 | 0.532 | |
| 3bgq | VX2 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.530 | |
| 4aoi | 4K0 | Hepatocyte growth factor receptor | 2.7.10.1 | 0.529 | |
| 1yhs | STU | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.522 | |
| 2jed | LG8 | Protein kinase C theta type | 2.7.11.13 | 0.521 | |
| 4deg | 0JJ | Hepatocyte growth factor receptor | 2.7.10.1 | 0.520 | |
| 4n70 | 2HX | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.517 | |
| 4k18 | 1OB | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.513 | |
| 3cy3 | JN5 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.510 | |
| 4mbl | 26L | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.510 | |
| 3zc5 | W9Z | Hepatocyte growth factor receptor | 2.7.10.1 | 0.509 | |
| 1yi4 | ADN | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.508 | |
| 2xj1 | XJ1 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.508 | |
| 3uix | Q17 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.506 | |
| 4dtk | 7LI | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.506 | |
| 2o65 | MYF | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.504 | |
| 3jxw | LXG | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.503 | |
| 4dym | IYZ | Activin receptor type-1 | 2.7.11.30 | 0.503 | |
| 2wkm | PFY | Hepatocyte growth factor receptor | 2.7.10.1 | 0.502 | |
| 3bgp | VX1 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.502 | |
| 1yi3 | LY2 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.501 | |
| 3r02 | UNM | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.501 | |
| 4k0y | 1OA | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.501 | |
| 4n6z | 2HW | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.501 | |
| 1xws | BI1 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.500 | |
| 2j2i | LY4 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.499 | |
| 3a99 | ANP | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.497 | |
| 3a60 | STU | Ribosomal protein S6 kinase beta-1 | 2.7.11.1 | 0.494 | |
| 3vbq | 0F5 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.494 | |
| 4hni | 16W | Casein kinase I isoform epsilon | 2.7.11.1 | 0.494 | |
| 4erw | STU | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.493 | |
| 4lmu | QUE | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.493 | |
| 4bcp | T3C | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.492 | |
| 4eny | J19 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.492 | |
| 2uzl | C94 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.491 | |
| 2vz6 | FEF | Calcium/calmodulin-dependent protein kinase type II subunit alpha | 2.7.11.17 | 0.491 | |
| 3c4e | C4E | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.491 | |
| 3say | OFT | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.491 | |
| 3uyt | 0CK | Casein kinase I isoform delta | 2.7.11.1 | 0.491 | |
| 3dcv | 55E | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.490 | |
| 3ddp | RC8 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.490 | |
| 3zxz | KRW | Hepatocyte growth factor receptor | 2.7.10.1 | 0.489 | |
| 2x1n | X1N | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.488 | |
| 3jpv | 1DR | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.488 | |
| 5dgz | L20 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.488 | |
| 2brm | DFZ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.487 | |
| 2obj | VRV | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.487 | |
| 4yuq | KS1 | Calmodulin-like domain protein kinase | / | 0.486 | |
| 2xik | J60 | Serine/threonine-protein kinase 25 | 2.7.11.1 | 0.485 | |
| 3jy0 | LYG | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.485 | |
| 5e8w | STU | TGF-beta receptor type-1 | 2.7.11.30 | 0.485 | |
| 4enx | Z20 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.484 | |
| 1oiu | N76 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.483 | |
| 1qcf | PP1 | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.483 | |
| 1e9h | INR | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.482 | |
| 3bgz | VX3 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.482 | |
| 3vrz | VRZ | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.481 | |
| 4aoj | V4Z | High affinity nerve growth factor receptor | 2.7.10.1 | 0.480 | |
| 1wvx | BD4 | Death-associated protein kinase 1 | 2.7.11.1 | 0.479 | |
| 2iw8 | 4SP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.479 | |
| 2w05 | FRT | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.479 | |
| 4i22 | IRE | Epidermal growth factor receptor | 2.7.10.1 | 0.479 | |
| 4i41 | MIX | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.479 | |
| 2nry | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.478 | |
| 2uze | C95 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.478 | |
| 3c50 | ADP | Rhodopsin kinase | / | 0.478 | |
| 2h8h | H8H | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.477 | |
| 2j4z | 626 | Aurora kinase A | 2.7.11.1 | 0.477 | |
| 3pjc | PJC | Tyrosine-protein kinase JAK3 | 2.7.10.2 | 0.477 | |
| 4a7c | E46 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.477 | |
| 4gih | 0X5 | Non-receptor tyrosine-protein kinase TYK2 | 2.7.10.2 | 0.477 | |
| 1oi9 | N20 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.476 | |
| 4c3f | 7KW | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.476 | |
| 4k1b | 1OC | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.476 | |
| 3vs4 | VSF | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.475 | |
| 4u97 | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.475 | |
| 1stc | STU | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.474 | |
| 2wpa | 889 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.474 | |
| 3r04 | UNQ | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.474 | |
| 4fob | 0US | ALK tyrosine kinase receptor | 2.7.10.1 | 0.474 | |
| 4idt | T28 | Mitogen-activated protein kinase kinase kinase 14 | 2.7.11.25 | 0.474 | |
| 4jia | 1K3 | Tyrosine-protein kinase JAK2 | / | 0.474 | |
| 1h1r | 6CP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.473 | |
| 1ogu | ST8 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.473 | |
| 4acg | 6LQ | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.473 | |
| 4eor | 4SP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.473 | |
| 4gu6 | 10N | Focal adhesion kinase 1 | 2.7.10.2 | 0.473 | |
| 1u54 | ACP | Activated CDC42 kinase 1 | / | 0.472 | |
| 3dtc | VIN | Mitogen-activated protein kinase kinase kinase 9 | 2.7.11.25 | 0.472 | |
| 3f69 | XDR | Serine/threonine-protein kinase PknB | 2.7.11.1 | 0.472 | |
| 3iw4 | LW4 | Protein kinase C alpha type | 2.7.11.13 | 0.472 | |
| 2hy8 | 1ST | Serine/threonine-protein kinase PAK 1 | 2.7.11.1 | 0.471 | |
| 2pwl | ACP | Fibroblast growth factor receptor 2 | / | 0.471 | |
| 2wot | ZZG | TGF-beta receptor type-1 | 2.7.11.30 | 0.471 | |
| 4eon | 1RO | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.471 | |
| 2bil | BI1 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.470 | |
| 3zbx | 6XE | Hepatocyte growth factor receptor | 2.7.10.1 | 0.470 | |
| 4fny | I3K | ALK tyrosine kinase receptor | 2.7.10.1 | 0.470 | |
| 1u4d | DBQ | Activated CDC42 kinase 1 | / | 0.469 | |
| 1xr1 | ANP | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.469 | |
| 3vs7 | KS1 | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.469 | |
| 4b7s | QLE | Cytochrome P450 monooxygenase PikC | / | 0.469 | |
| 4gfo | 0X2 | Non-receptor tyrosine-protein kinase TYK2 | 2.7.10.2 | 0.469 | |
| 4gmy | 0X5 | Tyrosine-protein kinase JAK2 | / | 0.469 | |
| 2e9u | A25 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.468 | |
| 2iw6 | QQ2 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.468 | |
| 3c1x | CKK | Hepatocyte growth factor receptor | 2.7.10.1 | 0.468 | |
| 3ma3 | 01I | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.468 | |
| 4a4l | 939 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.468 | |
| 4feq | 0T8 | Tyrosine-protein kinase receptor TYRO3 | 2.7.10.1 | 0.468 | |
| 1aq1 | STU | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.467 | |
| 2br1 | PFP | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.467 | |
| 3kf7 | L9G | Mitogen-activated protein kinase 14 | / | 0.467 | |
| 3l8p | 0CE | Angiopoietin-1 receptor | 2.7.10.1 | 0.467 | |
| 3vry | B43 | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.467 | |
| 4ftu | 7HK | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.467 | |
| 1oir | HDY | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.466 | |
| 2gcd | STU | Serine/threonine-protein kinase TAO2 | 2.7.11.1 | 0.466 | |
| 2i40 | BLZ | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.466 | |
| 2vgo | AD5 | Aurora kinase B-A | 2.7.11.1 | 0.466 | |
| 2w9s | TOP | Dihydrofolate reductase type 1 from Tn4003 | 1.5.1.3 | 0.466 | |
| 3l0l | HC3 | Nuclear receptor ROR-gamma | / | 0.466 | |
| 3mfs | ANP | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.466 | |
| 4gii | 0X6 | Non-receptor tyrosine-protein kinase TYK2 | 2.7.10.2 | 0.466 | |
| 2c0t | L3G | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.465 | |
| 2r0u | M54 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.465 | |
| 3lfq | A28 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.465 | |
| 4at3 | LTI | BDNF/NT-3 growth factors receptor | 2.7.10.1 | 0.465 | |
| 4bib | IEO | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.465 | |
| 2chl | DKI | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.464 | |
| 3bhe | BZN | Gag-Pol polyprotein | 3.4.23.16 | 0.464 | |
| 3cxw | 7CP | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.464 | |
| 1nvr | STU | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.463 | |
| 1oiy | N41 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.463 | |
| 2bik | BI1 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.463 | |
| 2hog | 710 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.463 | |
| 2qhm | 7CS | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.463 | |
| 3oom | 507 | Activin receptor type-1 | 2.7.11.30 | 0.463 | |
| 3zep | 1NX | Tyrosine-protein kinase JAK3 | 2.7.10.2 | 0.462 | |
| 4fg7 | ATP | Calcium/calmodulin-dependent protein kinase type 1 | 2.7.11.17 | 0.462 | |
| 4oac | ADP | Protein BRASSINOSTEROID INSENSITIVE 1 | 2.7.10.1 | 0.462 | |
| 2hxl | 422 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.461 | |
| 2j0j | 4ST | Focal adhesion kinase 1 | 2.7.10.2 | 0.461 | |
| 3hl7 | I47 | Mitogen-activated protein kinase 14 | / | 0.461 | |
| 3vs2 | VSB | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.461 | |
| 4bgg | 844 | Activin receptor type-1 | 2.7.11.30 | 0.461 | |
| 4c1i | EH9 | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.460 | |
| 4cy8 | FDA | 2-hydroxybiphenyl-3-monooxygenase | / | 0.460 | |
| 4kik | KSA | Inhibitor of nuclear factor kappa-B kinase subunit beta | 2.7.11.10 | 0.460 | |
| 4o70 | 1QK | Bromodomain-containing protein 4 | / | 0.460 | |
| 3qgt | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.459 | |
| 3vs0 | VS0 | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.459 | |
| 4z61 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.459 | |
| 1k6p | XN3 | Gag-Pol polyprotein | 3.4.23.16 | 0.458 | |
| 2c5n | CK8 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.458 | |
| 2etm | 7PY | Focal adhesion kinase 1 | 2.7.10.2 | 0.458 | |
| 2f4b | EHA | Peroxisome proliferator-activated receptor gamma | / | 0.458 | |
| 2vag | V25 | Dual specificity protein kinase CLK1 | 2.7.12.1 | 0.458 | |
| 3ncg | BK1 | Calmodulin-domain protein kinase 1, putative | / | 0.458 | |
| 4bf2 | STU | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.458 | |
| 4hvh | 19R | Tyrosine-protein kinase JAK3 | 2.7.10.2 | 0.458 | |
| 2b36 | 5PP | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.457 | |
| 2h96 | 893 | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.457 | |
| 3et7 | 349 | Protein-tyrosine kinase 2-beta | 2.7.10.2 | 0.457 | |
| 3mtl | FEF | Cyclin-dependent kinase 16 | 2.7.11.22 | 0.457 | |
| 3u9n | 09H | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.457 | |
| 3uzp | 0CK | Casein kinase I isoform delta | 2.7.11.1 | 0.457 | |
| 4foc | 0UU | ALK tyrosine kinase receptor | 2.7.10.1 | 0.457 | |
| 4z64 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.457 | |
| 5bvw | 1N1 | Epithelial discoidin domain-containing receptor 1 | 2.7.10.1 | 0.457 | |
| 1pkd | UCN | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.456 | |
| 1szm | BI4 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.456 | |
| 1v0p | PVB | Cell division control protein 2 homolog | 2.7.11.22 | 0.456 | |
| 2ym6 | YM6 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.456 | |
| 3mtf | A3F | Activin receptor type-1 | 2.7.11.30 | 0.456 | |
| 4bid | IE8 | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.456 | |
| 1nvs | UCM | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.455 | |
| 2b52 | D42 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.455 | |
| 2j0l | ANP | Focal adhesion kinase 1 | 2.7.10.2 | 0.455 | |
| 2wmx | ZY6 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.455 | |
| 2xa4 | AZ5 | Tyrosine-protein kinase JAK2 | / | 0.455 | |
| 4bch | T7Z | Cyclin-dependent kinase 9 | 2.7.11.22 | 0.455 | |
| 1nvq | UCN | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.454 | |
| 2brb | PFQ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.454 | |
| 2c3k | ABO | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.454 | |
| 2uxp | CLM | HTH-type transcriptional regulator TtgR | / | 0.454 | |
| 2uzb | C75 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.454 | |
| 2w1g | L0G | Aurora kinase A | 2.7.11.1 | 0.454 | |
| 4ft7 | H3K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.454 | |
| 4hge | 15V | Tyrosine-protein kinase JAK2 | / | 0.454 | |
| 4hnf | 16W | Casein kinase I isoform delta | 2.7.11.1 | 0.454 | |
| 5eyp | LOC | Tubulin beta chain | / | 0.454 | |
| 1vyw | 292 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.453 | |
| 1xuo | LA1 | Integrin alpha-L | / | 0.453 | |
| 3irn | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.453 | |
| 3vs5 | VSG | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.453 | |
| 4k11 | 0J9 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.453 | |
| 4l9i | 8PR | Rhodopsin kinase | / | 0.453 | |
| 4oth | DRN | Serine/threonine-protein kinase N1 | / | 0.453 | |
| 1ad5 | ANP | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.452 | |
| 2c3l | IDZ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.452 | |
| 2fm5 | M99 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.452 | |
| 2wih | P48 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.452 | |
| 2xck | MH4 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.452 | |
| 3ama | SKE | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.452 | |
| 3cy2 | MB9 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.452 | |
| 3vs6 | VSH | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.452 | |
| 4bco | T6Q | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.452 | |
| 4d4s | BI9 | Focal adhesion kinase 1 | 2.7.10.2 | 0.452 | |
| 1qpd | STU | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.451 | |
| 1zys | 199 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.451 | |
| 3fzr | 3JZ | Protein-tyrosine kinase 2-beta | 2.7.10.2 | 0.451 | |
| 4a06 | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.451 | |
| 4ib4 | ERM | 5-hydroxytryptamine receptor 2B | / | 0.451 | |
| 1xl2 | 189 | Gag-Pol polyprotein | 3.4.23.16 | 0.450 | |
| 2i1m | 5CN | Macrophage colony-stimulating factor 1 receptor | 2.7.10.1 | 0.450 | |
| 2y98 | MIV | Mycinamicin IV hydroxylase/epoxidase | / | 0.450 | |
| 3gub | GUB | Death-associated protein kinase 1 | 2.7.11.1 | 0.450 | |
| 3umx | Q18 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.450 | |
| 4bbe | 3O4 | Tyrosine-protein kinase JAK2 | / | 0.450 | |
| 4cax | 646 | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.450 | |
| 4e4m | 0NH | Tyrosine-protein kinase JAK2 | / | 0.450 | |
| 4yzc | STU | Serine/threonine-protein kinase/endoribonuclease IRE1 | 2.7.11.1 | 0.450 | |
| 1n83 | CLR | Nuclear receptor ROR-alpha | / | 0.449 | |
| 1qxl | FR8 | Adenosine deaminase | 3.5.4.4 | 0.449 | |
| 2ayp | 43A | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.449 | |
| 2c3i | IYZ | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.449 | |
| 2cch | ATP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.449 | |
| 2w3w | VG9 | Dihydrofolate reductase | / | 0.449 | |
| 3a7j | ADP | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.449 | |
| 3inx | JZC | Heat shock protein HSP 90-alpha | / | 0.449 | |
| 3nyn | SGV | G protein-coupled receptor kinase 6 | 2.7.11.16 | 0.449 | |
| 4bzn | UGX | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.449 | |
| 1eh4 | IC1 | Casein kinase I homolog 1 | 2.7.11.1 | 0.448 | |
| 1hfq | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 1klk | PMD | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 1uyf | PU1 | Heat shock protein HSP 90-alpha | / | 0.448 | |
| 2chw | 039 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.448 | |
| 2fwy | H64 | Heat shock protein HSP 90-alpha | / | 0.448 | |
| 2vuw | 5ID | Serine/threonine-protein kinase haspin | 2.7.11.1 | 0.448 | |
| 3cyl | VIT | Basic phospholipase A2 homolog piratoxin-2 | / | 0.448 | |
| 3mqe | 416 | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.448 | |
| 3tea | 4CO | 4-hydroxybenzoyl-CoA thioesterase | 3.1.2.23 | 0.448 | |
| 4a9h | TVP | Bromodomain-containing protein 2 | / | 0.448 | |
| 4acc | 7YG | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.448 | |
| 4c2y | MYA | Glycylpeptide N-tetradecanoyltransferase 1 | / | 0.448 | |
| 4eok | 4SP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.448 | |
| 4xx9 | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.448 | |
| 2bdj | HET | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.447 | |
| 2dq7 | STU | Tyrosine-protein kinase Fyn | 2.7.10.2 | 0.447 | |
| 2j0k | 4ST | Focal adhesion kinase 1 | 2.7.10.2 | 0.447 | |
| 3i8a | N22 | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 3k5u | PFQ | Aurora kinase A | 2.7.11.1 | 0.447 | |
| 3lcd | BDY | Macrophage colony-stimulating factor 1 receptor | 2.7.10.1 | 0.447 | |
| 3ort | AGS | Serine/threonine protein kinase | / | 0.447 | |
| 3vs1 | VSA | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.447 | |
| 4ct2 | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.447 | |
| 4ezl | 0SE | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.447 | |
| 4id7 | 1G0 | Activated CDC42 kinase 1 | / | 0.447 | |
| 4nk9 | 2K5 | Fibroblast growth factor receptor 1 | / | 0.447 | |
| 4qmx | H8H | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.447 | |
| 5dt3 | ATP | Aurora kinase A | 2.7.11.1 | 0.447 | |
| 1rf9 | DBR | Camphor 5-monooxygenase | 1.14.15.1 | 0.446 | |
| 1syn | F89 | Thymidylate synthase | / | 0.446 | |
| 2ykj | YKJ | Heat shock protein HSP 90-alpha | / | 0.446 | |
| 3uli | 1N3 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.446 | |
| 3um5 | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.446 | |
| 3um6 | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.446 | |
| 4a4o | 664 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.446 | |
| 4b8m | VX6 | Aurora kinase B-A | 2.7.11.1 | 0.446 | |
| 4hgl | 0YO | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.446 | |
| 5aaa | VGH | ALK tyrosine kinase receptor | 2.7.10.1 | 0.446 | |
| 1oky | STU | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.445 | |
| 3bkb | STU | Tyrosine-protein kinase Fes/Fps | 2.7.10.2 | 0.445 | |
| 3hx4 | ANP | Calmodulin-domain protein kinase 1 | / | 0.445 | |
| 3vt8 | YI3 | Vitamin D3 receptor | / | 0.445 | |
| 4anx | 534 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.445 | |
| 4bzo | 676 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.445 | |
| 4iar | ERM | 5-hydroxytryptamine receptor 1B | / | 0.445 | |
| 4k6z | 1Q3 | Tyrosine-protein kinase JAK1 | / | 0.445 | |
| 4ks8 | B49 | Serine/threonine-protein kinase PAK 6 | 2.7.11.1 | 0.445 | |
| 4qmt | H1N | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.445 | |
| 1jip | KTN | 6-deoxyerythronolide B hydroxylase | / | 0.444 | |
| 1pmn | 984 | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.444 | |
| 1vjy | 460 | TGF-beta receptor type-1 | 2.7.11.30 | 0.444 | |
| 2bro | DF2 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.444 | |
| 2duv | 371 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.444 | |
| 2xbj | XBJ | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.444 | |
| 2xru | 400 | Aurora kinase A | 2.7.11.1 | 0.444 | |
| 3a4o | STU | Tyrosine-protein kinase Lyn | 2.7.10.2 | 0.444 | |
| 3nlb | 5BE | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.444 | |
| 3tkh | 07S | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.444 | |
| 4bcq | TJF | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.444 | |
| 5drd | ATP | Aurora kinase A | 2.7.11.1 | 0.444 | |
| 2w3v | TOP | Dihydrofolate reductase | / | 0.443 | |
| 3bu5 | ATP | Insulin receptor | 2.7.10.1 | 0.443 | |
| 3e5a | VX6 | Aurora kinase A | 2.7.11.1 | 0.443 | |
| 3fco | IIG | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.443 | |
| 3l8s | BFF | Mitogen-activated protein kinase 14 | / | 0.443 | |
| 3ml8 | ML8 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.443 | |
| 3q4z | ANP | Serine/threonine-protein kinase PAK 1 | 2.7.11.1 | 0.443 | |
| 4ach | KDI | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.443 | |
| 4bqp | VMY | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.443 | |
| 4c34 | STU | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.443 | |
| 4ftc | H6K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.443 | |
| 4gj2 | 0XH | Non-receptor tyrosine-protein kinase TYK2 | 2.7.10.2 | 0.443 | |
| 4nc3 | ERM | 5-hydroxytryptamine receptor 2B | / | 0.443 | |
| 4riy | ADP | Epidermal growth factor receptor | 2.7.10.1 | 0.443 | |
| 5ajq | DB8 | Serine/threonine-protein kinase 10 | 2.7.11.1 | 0.443 | |
| 1k6c | MK1 | Gag-Pol polyprotein | 3.4.23.16 | 0.442 | |
| 1og5 | SWF | Cytochrome P450 2C9 | / | 0.442 | |
| 1vik | BAY | Gag-Pol polyprotein | / | 0.442 | |
| 1zth | ADP | RIO-type serine/threonine-protein kinase Rio1 | 2.7.11.1 | 0.442 | |
| 2cgw | 3C3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.442 | |
| 2fm0 | M98 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.442 | |
| 2izr | BRK | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.442 | |
| 2nru | T12 | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.442 | |
| 2qe4 | JJ3 | Estrogen receptor | / | 0.442 | |
| 2wmu | ZYU | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.442 | |
| 3el8 | PD5 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.442 | |
| 3i81 | EBI | Insulin-like growth factor 1 receptor | 2.7.10.1 | 0.442 | |
| 3qlg | 1N1 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.442 | |
| 3uim | ANP | BRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 1 | 2.7.10.1 | 0.442 | |
| 4dfn | 0K1 | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.442 | |
| 4jlj | 1NM | Deoxycytidine kinase | 2.7.1.74 | 0.442 | |
| 1byg | STU | Tyrosine-protein kinase CSK | / | 0.441 | |
| 1gy3 | ATP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.441 | |
| 1qnf | FAD | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.441 | |
| 2hcd | BIV | Vitamin D3 receptor A | / | 0.441 | |
| 2w1f | L0F | Aurora kinase A | 2.7.11.1 | 0.441 | |
| 3c4z | ADP | Rhodopsin kinase | / | 0.441 | |
| 3kga | LX9 | MAP kinase-activated protein kinase 2 | 2.7.11.1 | 0.441 | |
| 4kbk | 1QG | Casein kinase I isoform delta | 2.7.11.1 | 0.441 | |
| 5ar4 | SB2 | Receptor-interacting serine/threonine-protein kinase 2 | 2.7.11.1 | 0.441 | |
| 5auw | QUE | Death-associated protein kinase 1 | 2.7.11.1 | 0.441 | |
| 1p44 | GEQ | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.440 | |
| 1vj3 | TAB | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 2ijm | ATP | Focal adhesion kinase 1 | 2.7.10.2 | 0.440 | |
| 2itt | AEE | Epidermal growth factor receptor | 2.7.10.1 | 0.440 | |
| 2wms | ZYS | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.440 | |
| 3inv | C50 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.440 | |
| 3nwx | KVS | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
| 3qai | XNN | Ketohexokinase | / | 0.440 | |
| 3vt9 | YI4 | Vitamin D3 receptor | / | 0.440 | |
| 3zh8 | C58 | Protein kinase C iota type | 2.7.11.13 | 0.440 | |
| 4dgn | LU2 | Casein kinase II subunit alpha | 2.7.11.1 | 0.440 | |
| 4fsr | HKC | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.440 | |
| 4fv6 | E57 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.440 | |
| 4nh8 | 2LC | Heat shock protein HSP 90-alpha | / | 0.440 | |
| 4nks | 2M2 | Fibroblast growth factor receptor 1 | / | 0.440 | |
| 5auu | LU2 | Death-associated protein kinase 1 | 2.7.11.1 | 0.440 |