Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
PDB ID | HET | Uniprot Name | EC Number |
---|---|---|---|
3a4p | DFQ | Hepatocyte growth factor receptor | 2.7.10.1 |
PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
---|---|---|---|---|---|
3a4p | DFQ | Hepatocyte growth factor receptor | 2.7.10.1 | 1.000 | |
4gg7 | 0J8 | Hepatocyte growth factor receptor | 2.7.10.1 | 0.602 | |
2wgj | VGH | Hepatocyte growth factor receptor | 2.7.10.1 | 0.559 | |
4lm5 | Q17 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.550 | |
3zze | 6XP | Hepatocyte growth factor receptor | 2.7.10.1 | 0.549 | |
4gg5 | 0J3 | Hepatocyte growth factor receptor | 2.7.10.1 | 0.542 | |
1xjd | STU | Protein kinase C theta type | 2.7.11.13 | 0.538 | |
4ap7 | F47 | Hepatocyte growth factor receptor | 2.7.10.1 | 0.532 | |
3bgq | VX2 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.530 | |
4aoi | 4K0 | Hepatocyte growth factor receptor | 2.7.10.1 | 0.529 | |
1yhs | STU | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.522 | |
2jed | LG8 | Protein kinase C theta type | 2.7.11.13 | 0.521 | |
4deg | 0JJ | Hepatocyte growth factor receptor | 2.7.10.1 | 0.520 | |
4n70 | 2HX | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.517 | |
4k18 | 1OB | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.513 | |
3cy3 | JN5 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.510 | |
4mbl | 26L | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.510 | |
3zc5 | W9Z | Hepatocyte growth factor receptor | 2.7.10.1 | 0.509 | |
1yi4 | ADN | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.508 | |
2xj1 | XJ1 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.508 | |
3uix | Q17 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.506 | |
4dtk | 7LI | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.506 | |
2o65 | MYF | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.504 | |
3jxw | LXG | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.503 | |
4dym | IYZ | Activin receptor type-1 | 2.7.11.30 | 0.503 | |
2wkm | PFY | Hepatocyte growth factor receptor | 2.7.10.1 | 0.502 | |
3bgp | VX1 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.502 | |
1yi3 | LY2 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.501 | |
3r02 | UNM | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.501 | |
4k0y | 1OA | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.501 | |
4n6z | 2HW | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.501 | |
1xws | BI1 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.500 | |
2j2i | LY4 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.499 | |
3a99 | ANP | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.497 | |
3a60 | STU | Ribosomal protein S6 kinase beta-1 | 2.7.11.1 | 0.494 | |
3vbq | 0F5 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.494 | |
4hni | 16W | Casein kinase I isoform epsilon | 2.7.11.1 | 0.494 | |
4erw | STU | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.493 | |
4lmu | QUE | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.493 | |
4bcp | T3C | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.492 | |
4eny | J19 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.492 | |
2uzl | C94 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.491 | |
2vz6 | FEF | Calcium/calmodulin-dependent protein kinase type II subunit alpha | 2.7.11.17 | 0.491 | |
3c4e | C4E | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.491 | |
3say | OFT | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.491 | |
3uyt | 0CK | Casein kinase I isoform delta | 2.7.11.1 | 0.491 | |
3dcv | 55E | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.490 | |
3ddp | RC8 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.490 | |
3zxz | KRW | Hepatocyte growth factor receptor | 2.7.10.1 | 0.489 | |
2x1n | X1N | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.488 | |
3jpv | 1DR | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.488 | |
5dgz | L20 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.488 | |
2brm | DFZ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.487 | |
2obj | VRV | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.487 | |
4yuq | KS1 | Calmodulin-like domain protein kinase | / | 0.486 | |
2xik | J60 | Serine/threonine-protein kinase 25 | 2.7.11.1 | 0.485 | |
3jy0 | LYG | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.485 | |
5e8w | STU | TGF-beta receptor type-1 | 2.7.11.30 | 0.485 | |
4enx | Z20 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.484 | |
1oiu | N76 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.483 | |
1qcf | PP1 | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.483 | |
1e9h | INR | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.482 | |
3bgz | VX3 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.482 | |
3vrz | VRZ | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.481 | |
4aoj | V4Z | High affinity nerve growth factor receptor | 2.7.10.1 | 0.480 | |
1wvx | BD4 | Death-associated protein kinase 1 | 2.7.11.1 | 0.479 | |
2iw8 | 4SP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.479 | |
2w05 | FRT | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.479 | |
4i22 | IRE | Epidermal growth factor receptor | 2.7.10.1 | 0.479 | |
4i41 | MIX | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.479 | |
2nry | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.478 | |
2uze | C95 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.478 | |
3c50 | ADP | Rhodopsin kinase | / | 0.478 | |
2h8h | H8H | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.477 | |
2j4z | 626 | Aurora kinase A | 2.7.11.1 | 0.477 | |
3pjc | PJC | Tyrosine-protein kinase JAK3 | 2.7.10.2 | 0.477 | |
4a7c | E46 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.477 | |
4gih | 0X5 | Non-receptor tyrosine-protein kinase TYK2 | 2.7.10.2 | 0.477 | |
1oi9 | N20 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.476 | |
4c3f | 7KW | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.476 | |
4k1b | 1OC | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.476 | |
3vs4 | VSF | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.475 | |
4u97 | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.475 | |
1stc | STU | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.474 | |
2wpa | 889 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.474 | |
3r04 | UNQ | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.474 | |
4fob | 0US | ALK tyrosine kinase receptor | 2.7.10.1 | 0.474 | |
4idt | T28 | Mitogen-activated protein kinase kinase kinase 14 | 2.7.11.25 | 0.474 | |
4jia | 1K3 | Tyrosine-protein kinase JAK2 | / | 0.474 | |
1h1r | 6CP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.473 | |
1ogu | ST8 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.473 | |
4acg | 6LQ | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.473 | |
4eor | 4SP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.473 | |
4gu6 | 10N | Focal adhesion kinase 1 | 2.7.10.2 | 0.473 | |
1u54 | ACP | Activated CDC42 kinase 1 | / | 0.472 | |
3dtc | VIN | Mitogen-activated protein kinase kinase kinase 9 | 2.7.11.25 | 0.472 | |
3f69 | XDR | Serine/threonine-protein kinase PknB | 2.7.11.1 | 0.472 | |
3iw4 | LW4 | Protein kinase C alpha type | 2.7.11.13 | 0.472 | |
2hy8 | 1ST | Serine/threonine-protein kinase PAK 1 | 2.7.11.1 | 0.471 | |
2pwl | ACP | Fibroblast growth factor receptor 2 | / | 0.471 | |
2wot | ZZG | TGF-beta receptor type-1 | 2.7.11.30 | 0.471 | |
4eon | 1RO | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.471 | |
2bil | BI1 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.470 | |
3zbx | 6XE | Hepatocyte growth factor receptor | 2.7.10.1 | 0.470 | |
4fny | I3K | ALK tyrosine kinase receptor | 2.7.10.1 | 0.470 | |
1u4d | DBQ | Activated CDC42 kinase 1 | / | 0.469 | |
1xr1 | ANP | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.469 | |
3vs7 | KS1 | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.469 | |
4b7s | QLE | Cytochrome P450 monooxygenase PikC | / | 0.469 | |
4gfo | 0X2 | Non-receptor tyrosine-protein kinase TYK2 | 2.7.10.2 | 0.469 | |
4gmy | 0X5 | Tyrosine-protein kinase JAK2 | / | 0.469 | |
2e9u | A25 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.468 | |
2iw6 | QQ2 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.468 | |
3c1x | CKK | Hepatocyte growth factor receptor | 2.7.10.1 | 0.468 | |
3ma3 | 01I | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.468 | |
4a4l | 939 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.468 | |
4feq | 0T8 | Tyrosine-protein kinase receptor TYRO3 | 2.7.10.1 | 0.468 | |
1aq1 | STU | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.467 | |
2br1 | PFP | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.467 | |
3kf7 | L9G | Mitogen-activated protein kinase 14 | / | 0.467 | |
3l8p | 0CE | Angiopoietin-1 receptor | 2.7.10.1 | 0.467 | |
3vry | B43 | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.467 | |
4ftu | 7HK | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.467 | |
1oir | HDY | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.466 | |
2gcd | STU | Serine/threonine-protein kinase TAO2 | 2.7.11.1 | 0.466 | |
2i40 | BLZ | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.466 | |
2vgo | AD5 | Aurora kinase B-A | 2.7.11.1 | 0.466 | |
2w9s | TOP | Dihydrofolate reductase type 1 from Tn4003 | 1.5.1.3 | 0.466 | |
3l0l | HC3 | Nuclear receptor ROR-gamma | / | 0.466 | |
3mfs | ANP | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.466 | |
4gii | 0X6 | Non-receptor tyrosine-protein kinase TYK2 | 2.7.10.2 | 0.466 | |
2c0t | L3G | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.465 | |
2r0u | M54 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.465 | |
3lfq | A28 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.465 | |
4at3 | LTI | BDNF/NT-3 growth factors receptor | 2.7.10.1 | 0.465 | |
4bib | IEO | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.465 | |
2chl | DKI | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.464 | |
3bhe | BZN | Gag-Pol polyprotein | 3.4.23.16 | 0.464 | |
3cxw | 7CP | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.464 | |
1nvr | STU | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.463 | |
1oiy | N41 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.463 | |
2bik | BI1 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.463 | |
2hog | 710 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.463 | |
2qhm | 7CS | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.463 | |
3oom | 507 | Activin receptor type-1 | 2.7.11.30 | 0.463 | |
3zep | 1NX | Tyrosine-protein kinase JAK3 | 2.7.10.2 | 0.462 | |
4fg7 | ATP | Calcium/calmodulin-dependent protein kinase type 1 | 2.7.11.17 | 0.462 | |
4oac | ADP | Protein BRASSINOSTEROID INSENSITIVE 1 | 2.7.10.1 | 0.462 | |
2hxl | 422 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.461 | |
2j0j | 4ST | Focal adhesion kinase 1 | 2.7.10.2 | 0.461 | |
3hl7 | I47 | Mitogen-activated protein kinase 14 | / | 0.461 | |
3vs2 | VSB | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.461 | |
4bgg | 844 | Activin receptor type-1 | 2.7.11.30 | 0.461 | |
4c1i | EH9 | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.460 | |
4cy8 | FDA | 2-hydroxybiphenyl-3-monooxygenase | / | 0.460 | |
4kik | KSA | Inhibitor of nuclear factor kappa-B kinase subunit beta | 2.7.11.10 | 0.460 | |
4o70 | 1QK | Bromodomain-containing protein 4 | / | 0.460 | |
3qgt | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.459 | |
3vs0 | VS0 | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.459 | |
4z61 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.459 | |
1k6p | XN3 | Gag-Pol polyprotein | 3.4.23.16 | 0.458 | |
2c5n | CK8 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.458 | |
2etm | 7PY | Focal adhesion kinase 1 | 2.7.10.2 | 0.458 | |
2f4b | EHA | Peroxisome proliferator-activated receptor gamma | / | 0.458 | |
2vag | V25 | Dual specificity protein kinase CLK1 | 2.7.12.1 | 0.458 | |
3ncg | BK1 | Calmodulin-domain protein kinase 1, putative | / | 0.458 | |
4bf2 | STU | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.458 | |
4hvh | 19R | Tyrosine-protein kinase JAK3 | 2.7.10.2 | 0.458 | |
2b36 | 5PP | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.457 | |
2h96 | 893 | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.457 | |
3et7 | 349 | Protein-tyrosine kinase 2-beta | 2.7.10.2 | 0.457 | |
3mtl | FEF | Cyclin-dependent kinase 16 | 2.7.11.22 | 0.457 | |
3u9n | 09H | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.457 | |
3uzp | 0CK | Casein kinase I isoform delta | 2.7.11.1 | 0.457 | |
4foc | 0UU | ALK tyrosine kinase receptor | 2.7.10.1 | 0.457 | |
4z64 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.457 | |
5bvw | 1N1 | Epithelial discoidin domain-containing receptor 1 | 2.7.10.1 | 0.457 | |
1pkd | UCN | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.456 | |
1szm | BI4 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.456 | |
1v0p | PVB | Cell division control protein 2 homolog | 2.7.11.22 | 0.456 | |
2ym6 | YM6 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.456 | |
3mtf | A3F | Activin receptor type-1 | 2.7.11.30 | 0.456 | |
4bid | IE8 | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.456 | |
1nvs | UCM | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.455 | |
2b52 | D42 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.455 | |
2j0l | ANP | Focal adhesion kinase 1 | 2.7.10.2 | 0.455 | |
2wmx | ZY6 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.455 | |
2xa4 | AZ5 | Tyrosine-protein kinase JAK2 | / | 0.455 | |
4bch | T7Z | Cyclin-dependent kinase 9 | 2.7.11.22 | 0.455 | |
1nvq | UCN | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.454 | |
2brb | PFQ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.454 | |
2c3k | ABO | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.454 | |
2uxp | CLM | HTH-type transcriptional regulator TtgR | / | 0.454 | |
2uzb | C75 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.454 | |
2w1g | L0G | Aurora kinase A | 2.7.11.1 | 0.454 | |
4ft7 | H3K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.454 | |
4hge | 15V | Tyrosine-protein kinase JAK2 | / | 0.454 | |
4hnf | 16W | Casein kinase I isoform delta | 2.7.11.1 | 0.454 | |
5eyp | LOC | Tubulin beta chain | / | 0.454 | |
1vyw | 292 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.453 | |
1xuo | LA1 | Integrin alpha-L | / | 0.453 | |
3irn | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.453 | |
3vs5 | VSG | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.453 | |
4k11 | 0J9 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.453 | |
4l9i | 8PR | Rhodopsin kinase | / | 0.453 | |
4oth | DRN | Serine/threonine-protein kinase N1 | / | 0.453 | |
1ad5 | ANP | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.452 | |
2c3l | IDZ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.452 | |
2fm5 | M99 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.452 | |
2wih | P48 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.452 | |
2xck | MH4 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.452 | |
3ama | SKE | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.452 | |
3cy2 | MB9 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.452 | |
3vs6 | VSH | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.452 | |
4bco | T6Q | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.452 | |
4d4s | BI9 | Focal adhesion kinase 1 | 2.7.10.2 | 0.452 | |
1qpd | STU | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.451 | |
1zys | 199 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.451 | |
3fzr | 3JZ | Protein-tyrosine kinase 2-beta | 2.7.10.2 | 0.451 | |
4a06 | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.451 | |
4ib4 | ERM | 5-hydroxytryptamine receptor 2B | / | 0.451 | |
1xl2 | 189 | Gag-Pol polyprotein | 3.4.23.16 | 0.450 | |
2i1m | 5CN | Macrophage colony-stimulating factor 1 receptor | 2.7.10.1 | 0.450 | |
2y98 | MIV | Mycinamicin IV hydroxylase/epoxidase | / | 0.450 | |
3gub | GUB | Death-associated protein kinase 1 | 2.7.11.1 | 0.450 | |
3umx | Q18 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.450 | |
4bbe | 3O4 | Tyrosine-protein kinase JAK2 | / | 0.450 | |
4cax | 646 | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.450 | |
4e4m | 0NH | Tyrosine-protein kinase JAK2 | / | 0.450 | |
4yzc | STU | Serine/threonine-protein kinase/endoribonuclease IRE1 | 2.7.11.1 | 0.450 | |
1n83 | CLR | Nuclear receptor ROR-alpha | / | 0.449 | |
1qxl | FR8 | Adenosine deaminase | 3.5.4.4 | 0.449 | |
2ayp | 43A | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.449 | |
2c3i | IYZ | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.449 | |
2cch | ATP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.449 | |
2w3w | VG9 | Dihydrofolate reductase | / | 0.449 | |
3a7j | ADP | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.449 | |
3inx | JZC | Heat shock protein HSP 90-alpha | / | 0.449 | |
3nyn | SGV | G protein-coupled receptor kinase 6 | 2.7.11.16 | 0.449 | |
4bzn | UGX | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.449 | |
1eh4 | IC1 | Casein kinase I homolog 1 | 2.7.11.1 | 0.448 | |
1hfq | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
1klk | PMD | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
1uyf | PU1 | Heat shock protein HSP 90-alpha | / | 0.448 | |
2chw | 039 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.448 | |
2fwy | H64 | Heat shock protein HSP 90-alpha | / | 0.448 | |
2vuw | 5ID | Serine/threonine-protein kinase haspin | 2.7.11.1 | 0.448 | |
3cyl | VIT | Basic phospholipase A2 homolog piratoxin-2 | / | 0.448 | |
3mqe | 416 | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.448 | |
3tea | 4CO | 4-hydroxybenzoyl-CoA thioesterase | 3.1.2.23 | 0.448 | |
4a9h | TVP | Bromodomain-containing protein 2 | / | 0.448 | |
4acc | 7YG | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.448 | |
4c2y | MYA | Glycylpeptide N-tetradecanoyltransferase 1 | / | 0.448 | |
4eok | 4SP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.448 | |
4xx9 | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.448 | |
2bdj | HET | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.447 | |
2dq7 | STU | Tyrosine-protein kinase Fyn | 2.7.10.2 | 0.447 | |
2j0k | 4ST | Focal adhesion kinase 1 | 2.7.10.2 | 0.447 | |
3i8a | N22 | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
3k5u | PFQ | Aurora kinase A | 2.7.11.1 | 0.447 | |
3lcd | BDY | Macrophage colony-stimulating factor 1 receptor | 2.7.10.1 | 0.447 | |
3ort | AGS | Serine/threonine protein kinase | / | 0.447 | |
3vs1 | VSA | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.447 | |
4ct2 | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.447 | |
4ezl | 0SE | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.447 | |
4id7 | 1G0 | Activated CDC42 kinase 1 | / | 0.447 | |
4nk9 | 2K5 | Fibroblast growth factor receptor 1 | / | 0.447 | |
4qmx | H8H | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.447 | |
5dt3 | ATP | Aurora kinase A | 2.7.11.1 | 0.447 | |
1rf9 | DBR | Camphor 5-monooxygenase | 1.14.15.1 | 0.446 | |
1syn | F89 | Thymidylate synthase | / | 0.446 | |
2ykj | YKJ | Heat shock protein HSP 90-alpha | / | 0.446 | |
3uli | 1N3 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.446 | |
3um5 | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.446 | |
3um6 | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.446 | |
4a4o | 664 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.446 | |
4b8m | VX6 | Aurora kinase B-A | 2.7.11.1 | 0.446 | |
4hgl | 0YO | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.446 | |
5aaa | VGH | ALK tyrosine kinase receptor | 2.7.10.1 | 0.446 | |
1oky | STU | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.445 | |
3bkb | STU | Tyrosine-protein kinase Fes/Fps | 2.7.10.2 | 0.445 | |
3hx4 | ANP | Calmodulin-domain protein kinase 1 | / | 0.445 | |
3vt8 | YI3 | Vitamin D3 receptor | / | 0.445 | |
4anx | 534 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.445 | |
4bzo | 676 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.445 | |
4iar | ERM | 5-hydroxytryptamine receptor 1B | / | 0.445 | |
4k6z | 1Q3 | Tyrosine-protein kinase JAK1 | / | 0.445 | |
4ks8 | B49 | Serine/threonine-protein kinase PAK 6 | 2.7.11.1 | 0.445 | |
4qmt | H1N | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.445 | |
1jip | KTN | 6-deoxyerythronolide B hydroxylase | / | 0.444 | |
1pmn | 984 | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.444 | |
1vjy | 460 | TGF-beta receptor type-1 | 2.7.11.30 | 0.444 | |
2bro | DF2 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.444 | |
2duv | 371 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.444 | |
2xbj | XBJ | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.444 | |
2xru | 400 | Aurora kinase A | 2.7.11.1 | 0.444 | |
3a4o | STU | Tyrosine-protein kinase Lyn | 2.7.10.2 | 0.444 | |
3nlb | 5BE | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.444 | |
3tkh | 07S | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.444 | |
4bcq | TJF | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.444 | |
5drd | ATP | Aurora kinase A | 2.7.11.1 | 0.444 | |
2w3v | TOP | Dihydrofolate reductase | / | 0.443 | |
3bu5 | ATP | Insulin receptor | 2.7.10.1 | 0.443 | |
3e5a | VX6 | Aurora kinase A | 2.7.11.1 | 0.443 | |
3fco | IIG | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.443 | |
3l8s | BFF | Mitogen-activated protein kinase 14 | / | 0.443 | |
3ml8 | ML8 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.443 | |
3q4z | ANP | Serine/threonine-protein kinase PAK 1 | 2.7.11.1 | 0.443 | |
4ach | KDI | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.443 | |
4bqp | VMY | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.443 | |
4c34 | STU | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.443 | |
4ftc | H6K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.443 | |
4gj2 | 0XH | Non-receptor tyrosine-protein kinase TYK2 | 2.7.10.2 | 0.443 | |
4nc3 | ERM | 5-hydroxytryptamine receptor 2B | / | 0.443 | |
4riy | ADP | Epidermal growth factor receptor | 2.7.10.1 | 0.443 | |
5ajq | DB8 | Serine/threonine-protein kinase 10 | 2.7.11.1 | 0.443 | |
1k6c | MK1 | Gag-Pol polyprotein | 3.4.23.16 | 0.442 | |
1og5 | SWF | Cytochrome P450 2C9 | / | 0.442 | |
1vik | BAY | Gag-Pol polyprotein | / | 0.442 | |
1zth | ADP | RIO-type serine/threonine-protein kinase Rio1 | 2.7.11.1 | 0.442 | |
2cgw | 3C3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.442 | |
2fm0 | M98 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.442 | |
2izr | BRK | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.442 | |
2nru | T12 | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.442 | |
2qe4 | JJ3 | Estrogen receptor | / | 0.442 | |
2wmu | ZYU | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.442 | |
3el8 | PD5 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.442 | |
3i81 | EBI | Insulin-like growth factor 1 receptor | 2.7.10.1 | 0.442 | |
3qlg | 1N1 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.442 | |
3uim | ANP | BRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 1 | 2.7.10.1 | 0.442 | |
4dfn | 0K1 | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.442 | |
4jlj | 1NM | Deoxycytidine kinase | 2.7.1.74 | 0.442 | |
1byg | STU | Tyrosine-protein kinase CSK | / | 0.441 | |
1gy3 | ATP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.441 | |
1qnf | FAD | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.441 | |
2hcd | BIV | Vitamin D3 receptor A | / | 0.441 | |
2w1f | L0F | Aurora kinase A | 2.7.11.1 | 0.441 | |
3c4z | ADP | Rhodopsin kinase | / | 0.441 | |
3kga | LX9 | MAP kinase-activated protein kinase 2 | 2.7.11.1 | 0.441 | |
4kbk | 1QG | Casein kinase I isoform delta | 2.7.11.1 | 0.441 | |
5ar4 | SB2 | Receptor-interacting serine/threonine-protein kinase 2 | 2.7.11.1 | 0.441 | |
5auw | QUE | Death-associated protein kinase 1 | 2.7.11.1 | 0.441 | |
1p44 | GEQ | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.440 | |
1vj3 | TAB | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
2ijm | ATP | Focal adhesion kinase 1 | 2.7.10.2 | 0.440 | |
2itt | AEE | Epidermal growth factor receptor | 2.7.10.1 | 0.440 | |
2wms | ZYS | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.440 | |
3inv | C50 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.440 | |
3nwx | KVS | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
3qai | XNN | Ketohexokinase | / | 0.440 | |
3vt9 | YI4 | Vitamin D3 receptor | / | 0.440 | |
3zh8 | C58 | Protein kinase C iota type | 2.7.11.13 | 0.440 | |
4dgn | LU2 | Casein kinase II subunit alpha | 2.7.11.1 | 0.440 | |
4fsr | HKC | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.440 | |
4fv6 | E57 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.440 | |
4nh8 | 2LC | Heat shock protein HSP 90-alpha | / | 0.440 | |
4nks | 2M2 | Fibroblast growth factor receptor 1 | / | 0.440 | |
5auu | LU2 | Death-associated protein kinase 1 | 2.7.11.1 | 0.440 |