Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2i17 | LDT | Aldose reductase | 1.1.1.21 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 2i17 | LDT | Aldose reductase | 1.1.1.21 | 1.000 | |
| 3ght | LDT | Aldose reductase | 1.1.1.21 | 0.904 | |
| 3ghs | LDT | Aldose reductase | 1.1.1.21 | 0.856 | |
| 3ld5 | LDT | Aldose reductase | 1.1.1.21 | 0.843 | |
| 3ghu | LDT | Aldose reductase | 1.1.1.21 | 0.831 | |
| 3ghr | LDT | Aldose reductase | 1.1.1.21 | 0.821 | |
| 1us0 | LDT | Aldose reductase | 1.1.1.21 | 0.787 | |
| 2qxw | LDT | Aldose reductase | 1.1.1.21 | 0.780 | |
| 2dux | ZST | Aldose reductase | 1.1.1.21 | 0.764 | |
| 2duz | ZST | Aldose reductase | 1.1.1.21 | 0.720 | |
| 2hvo | ZST | Aldose reductase | 1.1.1.21 | 0.716 | |
| 2i16 | LDT | Aldose reductase | 1.1.1.21 | 0.713 | |
| 3g5e | Q74 | Aldose reductase | 1.1.1.21 | 0.712 | |
| 2pdi | ZST | Aldose reductase | 1.1.1.21 | 0.698 | |
| 1z3n | 3NA | Aldose reductase | 1.1.1.21 | 0.689 | |
| 2pdg | 47D | Aldose reductase | 1.1.1.21 | 0.685 | |
| 2pzn | 393 | Aldose reductase | 1.1.1.21 | 0.683 | |
| 3mb9 | ZST | Aldose reductase | 1.1.1.21 | 0.674 | |
| 4yu1 | 53N | Aldose reductase | 1.1.1.21 | 0.671 | |
| 2iki | 388 | Aldose reductase | 1.1.1.21 | 0.658 | |
| 1pwl | BFI | Aldose reductase | 1.1.1.21 | 0.654 | |
| 2fz8 | ZST | Aldose reductase | 1.1.1.21 | 0.654 | |
| 1t40 | ID5 | Aldose reductase | 1.1.1.21 | 0.652 | |
| 2pdh | 47D | Aldose reductase | 1.1.1.21 | 0.633 | |
| 4gca | 2X9 | Aldose reductase | 1.1.1.21 | 0.632 | |
| 2pdl | TOL | Aldose reductase | 1.1.1.21 | 0.628 | |
| 2pdu | 393 | Aldose reductase | 1.1.1.21 | 0.628 | |
| 3lbo | LDT | Aldose reductase | 1.1.1.21 | 0.627 | |
| 2pdp | 393 | Aldose reductase | 1.1.1.21 | 0.625 | |
| 1z89 | 62P | Aldose reductase | 1.1.1.21 | 0.620 | |
| 2pdf | ZST | Aldose reductase | 1.1.1.21 | 0.617 | |
| 2hv5 | ZST | Aldose reductase | 1.1.1.21 | 0.614 | |
| 2hvn | ZST | Aldose reductase | 1.1.1.21 | 0.614 | |
| 3mc5 | 393 | Aldose reductase | 1.1.1.21 | 0.612 | |
| 3lql | LDT | Aldose reductase | 1.1.1.21 | 0.611 | |
| 1frb | ZST | Aldose reductase-related protein 2 | / | 0.610 | |
| 2pdx | ZST | Aldose reductase | 1.1.1.21 | 0.610 | |
| 2pdn | 47D | Aldose reductase | 1.1.1.21 | 0.609 | |
| 2pdb | ZST | Aldose reductase | 1.1.1.21 | 0.604 | |
| 2pdm | ZST | Aldose reductase | 1.1.1.21 | 0.602 | |
| 3m0i | ZST | Aldose reductase | 1.1.1.21 | 0.602 | |
| 2pd5 | ZST | Aldose reductase | 1.1.1.21 | 0.600 | |
| 3t42 | 3T4 | Aldose reductase | 1.1.1.21 | 0.599 | |
| 3len | ZST | Aldose reductase | 1.1.1.21 | 0.597 | |
| 1t41 | ID5 | Aldose reductase | 1.1.1.21 | 0.594 | |
| 3m64 | 393 | Aldose reductase | 1.1.1.21 | 0.594 | |
| 2pdc | 393 | Aldose reductase | 1.1.1.21 | 0.593 | |
| 2pdj | 393 | Aldose reductase | 1.1.1.21 | 0.592 | |
| 2dv0 | ZST | Aldose reductase | 1.1.1.21 | 0.588 | |
| 2pdq | 47D | Aldose reductase | 1.1.1.21 | 0.587 | |
| 3lz5 | LDT | Aldose reductase | 1.1.1.21 | 0.584 | |
| 3m4h | 388 | Aldose reductase | 1.1.1.21 | 0.583 | |
| 1iei | ZES | Aldose reductase | 1.1.1.21 | 0.579 | |
| 1ah3 | TOL | Aldose reductase | 1.1.1.21 | 0.566 | |
| 2inz | OHP | Aldose reductase | 1.1.1.21 | 0.566 | |
| 1zua | TOL | Aldo-keto reductase family 1 member B10 | 1.1.1 | 0.563 | |
| 2ikh | LIT | Aldose reductase | 1.1.1.21 | 0.554 | |
| 2pdy | FID | Aldose reductase | 1.1.1.21 | 0.548 | |
| 2iqd | LPA | Aldose reductase | 1.1.1.21 | 0.546 | |
| 2ikj | 393 | Aldose reductase | 1.1.1.21 | 0.541 | |
| 2fzb | TOL | Aldose reductase | 1.1.1.21 | 0.532 | |
| 2fzd | TOL | Aldose reductase | 1.1.1.21 | 0.531 | |
| 2is7 | 2CL | Aldose reductase | 1.1.1.21 | 0.527 | |
| 2fz9 | ZST | Aldose reductase | 1.1.1.21 | 0.525 | |
| 2f2k | TGG | Aldose reductase | 1.1.1.21 | 0.519 | |
| 1el3 | I84 | Aldose reductase | 1.1.1.21 | 0.518 | |
| 2yne | YNE | Glycylpeptide N-tetradecanoyltransferase | / | 0.513 | |
| 1eko | I84 | Aldose reductase | 1.1.1.21 | 0.512 | |
| 2pdk | SBI | Aldose reductase | 1.1.1.21 | 0.509 | |
| 1yw7 | A41 | Methionine aminopeptidase 2 | / | 0.502 | |
| 2agt | FID | Aldose reductase | 1.1.1.21 | 0.501 | |
| 4u16 | 3C0 | Muscarinic acetylcholine receptor M3 | / | 0.499 | |
| 4ga8 | SBI | Aldo-keto reductase family 1 member B10 | 1.1.1 | 0.498 | |
| 1y2d | 4DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.497 | |
| 3p2v | DOY | Aldose reductase | 1.1.1.21 | 0.495 | |
| 4bbh | YBN | Glycylpeptide N-tetradecanoyltransferase | / | 0.495 | |
| 4li8 | 1XQ | Tankyrase-1 | 2.4.2.30 | 0.493 | |
| 3g49 | 3G4 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.491 | |
| 3jsx | CC2 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.490 | |
| 4b12 | C23 | Glycylpeptide N-tetradecanoyltransferase | / | 0.490 | |
| 2aot | 2PM | Histamine N-methyltransferase | 2.1.1.8 | 0.489 | |
| 3zec | ANP | Adenosine monophosphate-protein transferase SoFic | 2.7.7.n1 | 0.489 | |
| 4jt8 | 1NR | NAD-dependent protein deacetylase sirtuin-3, mitochondrial | 3.5.1 | 0.488 | |
| 2aov | C2M | Histamine N-methyltransferase | 2.1.1.8 | 0.487 | |
| 3uzz | TES | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.486 | |
| 3s3g | TLT | Aldose reductase | 1.1.1.21 | 0.485 | |
| 3g4k | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.483 | |
| 4c2z | 646 | Glycylpeptide N-tetradecanoyltransferase 1 | / | 0.483 | |
| 4kmz | FOL | Folate receptor beta | / | 0.483 | |
| 4kn2 | LYA | Folate receptor beta | / | 0.483 | |
| 5cxv | 0HK | Muscarinic acetylcholine receptor M1 | / | 0.481 | |
| 1h35 | R01 | Squalene--hopene cyclase | 4.2.1.129 | 0.479 | |
| 1ry0 | PG2 | Aldo-keto reductase family 1 member C3 | / | 0.478 | |
| 4b11 | 7I1 | Glycylpeptide N-tetradecanoyltransferase | / | 0.478 | |
| 5liu | 388 | Aldo-keto reductase family 1 member B10 | 1.1.1 | 0.478 | |
| 1q9m | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.477 | |
| 4jsr | 1NQ | NAD-dependent protein deacetylase sirtuin-3, mitochondrial | 3.5.1 | 0.477 | |
| 3f3y | 4OA | Bile salt sulfotransferase | 2.8.2.14 | 0.476 | |
| 4dbu | BT9 | Aldo-keto reductase family 1 member C3 | / | 0.476 | |
| 4dbw | 511 | Aldo-keto reductase family 1 member C3 | / | 0.476 | |
| 1q23 | FUA | Chloramphenicol acetyltransferase | 2.3.1.28 | 0.474 | |
| 2ipi | AKY | Aclacinomycin-N/aclacinomycin-A oxidase | / | 0.474 | |
| 4bft | ZVT | Pantothenate kinase | 2.7.1.33 | 0.474 | |
| 4drj | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.474 | |
| 4drj | RAP | Peptidyl-prolyl cis-trans isomerase FKBP4 | 5.2.1.8 | 0.474 | |
| 4pab | THG | Dimethylglycine dehydrogenase, mitochondrial | 1.5.8.4 | 0.474 | |
| 1ah0 | SBI | Aldose reductase | 1.1.1.21 | 0.473 | |
| 1s9d | AFB | Cytohesin-2 | / | 0.473 | |
| 1s9d | AFB | ADP-ribosylation factor 1 | / | 0.473 | |
| 4a2z | VIQ | Glycylpeptide N-tetradecanoyltransferase | / | 0.473 | |
| 3v35 | NTI | Aldose reductase | 1.1.1.21 | 0.472 | |
| 4b13 | X25 | Glycylpeptide N-tetradecanoyltransferase | / | 0.472 | |
| 4paa | THG | Dimethylglycine dehydrogenase, mitochondrial | 1.5.8.4 | 0.472 | |
| 2cek | N8T | Acetylcholinesterase | 3.1.1.7 | 0.471 | |
| 2wsa | 646 | Glycylpeptide N-tetradecanoyltransferase | / | 0.471 | |
| 3uzx | AOX | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.471 | |
| 3hii | PNT | Amiloride-sensitive amine oxidase [copper-containing] | / | 0.470 | |
| 3u9f | CLM | Chloramphenicol acetyltransferase | 2.3.1.28 | 0.470 | |
| 4jq4 | IMN | Aldo-keto reductase family 1 member C2 | / | 0.470 | |
| 2ga2 | A19 | Methionine aminopeptidase 2 | / | 0.469 | |
| 3u2c | SUZ | Aldose reductase | 1.1.1.21 | 0.469 | |
| 4es5 | MGT | Polymerase basic protein 2 | / | 0.469 | |
| 4fam | 0SZ | Aldo-keto reductase family 1 member C3 | / | 0.469 | |
| 1x8l | OXR | Retinol dehydratase | / | 0.468 | |
| 2f38 | 15M | Aldo-keto reductase family 1 member C3 | / | 0.467 | |
| 4lsa | BLD | Protein BRASSINOSTEROID INSENSITIVE 1 | 2.7.10.1 | 0.467 | |
| 2v0m | KLN | Cytochrome P450 3A4 | / | 0.466 | |
| 2xup | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.466 | |
| 4b14 | 4XB | Glycylpeptide N-tetradecanoyltransferase | / | 0.466 | |
| 3rj0 | BLD | Protein BRASSINOSTEROID INSENSITIVE 1 | 2.7.10.1 | 0.465 | |
| 4mt9 | 2D6 | Tankyrase-1 | 2.4.2.30 | 0.465 | |
| 4wev | SUZ | Aldo-keto reductase family 1 member B10 | 1.1.1 | 0.465 | |
| 3n3z | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.464 | |
| 3r8h | ZOM | Aldo-keto reductase family 1 member C3 | / | 0.464 | |
| 4std | BFS | Scytalone dehydratase | 4.2.1.94 | 0.464 | |
| 1rxj | BNI | Streptavidin | / | 0.463 | |
| 1s2c | FLF | Aldo-keto reductase family 1 member C3 | / | 0.463 | |
| 1xf0 | ASD | Aldo-keto reductase family 1 member C3 | / | 0.463 | |
| 1zkn | IBM | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.463 | |
| 2xuh | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.463 | |
| 3aiv | HBO | 4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase, chloroplastic | 3.2.1.182 | 0.463 | |
| 3nub | UD0 | UDP-2-acetamido-2-deoxy-3-oxo-D-glucuronate aminotransferase | 2.6.1.98 | 0.463 | |
| 3zku | HCV | Isopenicillin N synthase | 1.21.3.1 | 0.463 | |
| 1lke | DOG | Bilin-binding protein | / | 0.462 | |
| 1zgb | A1E | Acetylcholinesterase | 3.1.1.7 | 0.462 | |
| 2nvc | ITA | Aldose reductase | 1.1.1.21 | 0.462 | |
| 3ghv | GHC | Dihydrofolate reductase | 1.5.1.3 | 0.462 | |
| 3uwe | VJJ | Aldo-keto reductase family 1 member C3 | / | 0.462 | |
| 4g2l | 0WL | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.462 | |
| 4li6 | 1XO | Tankyrase-1 | 2.4.2.30 | 0.462 | |
| 1pj6 | FOL | Dimethylglycine oxidase | 1.5.3.10 | 0.461 | |
| 2xui | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.461 | |
| 4ea2 | RWZ | Dehydrosqualene synthase | / | 0.461 | |
| 4u14 | 0HK | Muscarinic acetylcholine receptor M3 | / | 0.461 | |
| 1sg0 | STL | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.460 | |
| 2vqq | TFG | Histone deacetylase 4 | 3.5.1.98 | 0.460 | |
| 3cgt | BCD | Cyclomaltodextrin glucanotransferase | 2.4.1.19 | 0.460 | |
| 3dyq | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.460 | |
| 2xuj | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.459 | |
| 3r6i | JMS | Aldo-keto reductase family 1 member C3 | / | 0.459 | |
| 4i5x | FLF | Aldo-keto reductase family 1 member B10 | 1.1.1 | 0.459 | |
| 4lcw | 1VY | Major histocompatibility complex class I-related gene protein | / | 0.459 | |
| 4myq | 19T | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.459 | |
| 2cbq | TH2 | Neocarzinostatin | / | 0.458 | |
| 3n0h | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.458 | |
| 4eil | FOL | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.458 | |
| 4jvn | YUG | Estrogen sulfotransferase | 2.8.2.4 | 0.458 | |
| 4kn1 | 04J | Folate receptor beta | / | 0.458 | |
| 1ihi | IU5 | Aldo-keto reductase family 1 member C2 | / | 0.457 | |
| 2fm5 | M99 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.457 | |
| 3hxe | BD8 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.457 | |
| 3w2e | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.457 | |
| 4ajm | 3A6 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.457 | |
| 4li7 | 1XP | Tankyrase-1 | 2.4.2.30 | 0.457 | |
| 4mrx | CZH | Obelin | / | 0.457 | |
| 4zzi | 1NS | NAD-dependent protein deacetylase sirtuin-1 | 3.5.1 | 0.457 | |
| 5std | UNN | Scytalone dehydratase | 4.2.1.94 | 0.457 | |
| 1oyn | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.456 | |
| 1u70 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.456 | |
| 3gf4 | UPG | UDP-galactopyranose mutase | 5.4.99.9 | 0.456 | |
| 4gi2 | NAP | Crotonyl-CoA carboxylase/reductase | / | 0.456 | |
| 1xoq | ROF | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.455 | |
| 1zgc | A2E | Acetylcholinesterase | 3.1.1.7 | 0.455 | |
| 2cmf | F11 | Acetylcholinesterase | 3.1.1.7 | 0.455 | |
| 3dyl | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.455 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.455 | |
| 4gn6 | TYL | Lactoperoxidase | 1.11.1.7 | 0.455 | |
| 4kn0 | MTX | Folate receptor beta | / | 0.455 | |
| 4kp6 | 1S1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.455 | |
| 1jqd | SAH | Histamine N-methyltransferase | 2.1.1.8 | 0.454 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.454 | |
| 1xon | PIL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.454 | |
| 2aou | CQA | Histamine N-methyltransferase | 2.1.1.8 | 0.454 | |
| 2ckm | AA7 | Acetylcholinesterase | 3.1.1.7 | 0.454 | |
| 2d06 | EST | Sulfotransferase 1A1 | 2.8.2.1 | 0.454 | |
| 4e0u | 0MV | Cyclic dipeptide N-prenyltransferase | / | 0.454 | |
| 4mvh | 2F5 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.454 | |
| 4x7z | ZM3 | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.454 | |
| 4xo7 | ASD | Aldo-keto reductase family 1 member C2 | / | 0.454 | |
| 1lnm | DTX | Bilin-binding protein | / | 0.453 | |
| 2ea4 | F79 | Methionine aminopeptidase 2 | / | 0.453 | |
| 2i65 | NAD | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.453 | |
| 2zsd | COA | Pantothenate kinase | 2.7.1.33 | 0.453 | |
| 3g4i | D71 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.453 | |
| 3gmd | 2M3 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.453 | |
| 3tfj | THG | Dimethylsulfonioproprionate demethylase DmdA | 2.1.1.269 | 0.453 | |
| 3uzx | AOM | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.453 | |
| 4hmn | 16J | Aldo-keto reductase family 1 member C3 | / | 0.453 | |
| 1icq | OPD | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.452 | |
| 1ndy | FR3 | Adenosine deaminase | 3.5.4.4 | 0.452 | |
| 2psj | CEI | Renilla-luciferin 2-monooxygenase | 1.13.12.5 | 0.452 | |
| 2qx7 | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.452 | |
| 2wey | EV1 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.452 | |
| 3bur | TES | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.452 | |
| 3wav | DWV | Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 | 3.1.4.39 | 0.452 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.452 | |
| 4dbs | 0HV | Aldo-keto reductase family 1 member C3 | / | 0.452 | |
| 4hf4 | 15H | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.452 | |
| 4htx | 19F | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.452 | |
| 1s36 | CEI | Obelin | / | 0.451 | |
| 3g72 | A6T | Renin | 3.4.23.15 | 0.451 | |
| 3qpp | PFW | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.451 | |
| 4ey7 | E20 | Acetylcholinesterase | 3.1.1.7 | 0.451 | |
| 4lrh | FOL | Folate receptor alpha | / | 0.451 | |
| 4pnm | NU1 | Tankyrase-2 | 2.4.2.30 | 0.451 | |
| 5fd8 | A5A | Putative carboxypeptidase yocD | / | 0.451 | |
| 1efy | BZC | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.450 | |
| 1v08 | NTZ | 4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase 1, chloroplastic | 3.2.1.182 | 0.450 | |
| 1xor | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.450 | |
| 3k4s | 0MO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.450 | |
| 4a95 | 9MT | Glycylpeptide N-tetradecanoyltransferase | / | 0.450 | |
| 4bfs | ZVS | Pantothenate kinase | 2.7.1.33 | 0.450 | |
| 4fcb | 0T7 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.450 | |
| 1e66 | HUX | Acetylcholinesterase | 3.1.1.7 | 0.449 | |
| 1fap | RAP | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.449 | |
| 1fap | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.449 | |
| 1soj | IBM | cGMP-inhibited 3',5'-cyclic phosphodiesterase B | 3.1.4.17 | 0.449 | |
| 1tbb | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.449 | |
| 1y2b | DEE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.449 | |
| 2xtb | KRM | Adenosine kinase, putative | / | 0.449 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.449 | |
| 3hbf | MYC | Flavonoid 3-O-glucosyltransferase | 2.4.1 | 0.449 | |
| 4a32 | 2CD | Glycylpeptide N-tetradecanoyltransferase | / | 0.449 | |
| 3d4s | TIM | Beta-2 adrenergic receptor | / | 0.449 | |
| 1qvt | PRL | HTH-type transcriptional regulator QacR | / | 0.448 | |
| 1y2k | 7DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.448 | |
| 1zkl | IBM | High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A | 3.1.4.53 | 0.448 | |
| 3cot | STR | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.448 | |
| 3jq8 | DX3 | Pteridine reductase, putative | / | 0.448 | |
| 3lz6 | A0D | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.448 | |
| 5c1g | GDU | Histo-blood group ABO system transferase | / | 0.448 | |
| 1rpw | DID | HTH-type transcriptional regulator QacR | / | 0.447 | |
| 2o8h | 227 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.447 | |
| 4bb2 | STR | Corticosteroid-binding globulin | / | 0.447 | |
| 4gtv | 7TR | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.447 | |
| 4hhz | 15S | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.447 | |
| 4jt9 | 1NS | NAD-dependent protein deacetylase sirtuin-3, mitochondrial | 3.5.1 | 0.447 | |
| 5d5a | CAU | Beta-2 adrenergic receptor | / | 0.447 | |
| 2get | COK | Pantothenate kinase | 2.7.1.33 | 0.446 | |
| 2oaz | I96 | Methionine aminopeptidase 2 | / | 0.446 | |
| 3d3p | 20A | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.446 | |
| 3nhl | YTR | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.446 | |
| 3q9b | B3N | Acetylpolyamine amidohydrolase | / | 0.446 | |
| 3r58 | NPS | Aldo-keto reductase family 1 member C3 | / | 0.446 | |
| 3v94 | WYQ | Phosphodiesterase | / | 0.446 | |
| 4n9q | FMN | FMN-dependent NADH-azoreductase 1 | / | 0.446 | |
| 1eno | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH], chloroplastic | 1.3.1.9 | 0.445 | |
| 1qv0 | CZH | Obelin | / | 0.445 | |
| 1y2c | 3DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.445 | |
| 1yw9 | A84 | Methionine aminopeptidase 2 | / | 0.445 | |
| 1zq5 | E04 | Aldo-keto reductase family 1 member C3 | / | 0.445 | |
| 2bfm | TOP | Pteridine reductase 1 | 1.5.1.33 | 0.445 | |
| 2xuq | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.445 | |
| 3qi4 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.445 | |
| 3uzz | ASD | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.445 | |
| 4at4 | T6E | BDNF/NT-3 growth factors receptor | 2.7.10.1 | 0.445 | |
| 4m6l | 21V | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 4xba | 5GP | Aprataxin-like protein | 3 | 0.445 | |
| 1hfr | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 1mrq | STR | Aldo-keto reductase family 1 member C1 | / | 0.444 | |
| 1odc | A8B | Acetylcholinesterase | 3.1.1.7 | 0.444 | |
| 1p0p | BCH | Cholinesterase | 3.1.1.8 | 0.444 | |
| 1ro6 | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.444 | |
| 2ouy | CMP | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.444 | |
| 2zu9 | GDP | Mannosyl-3-phosphoglycerate synthase | 2.4.1.217 | 0.444 | |
| 3af1 | GDP | Pantothenate kinase | 2.7.1.33 | 0.444 | |
| 3cas | ASD | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.444 | |
| 3iak | EV1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.444 | |
| 4drh | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.444 | |
| 4drh | RAP | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.444 | |
| 1dgb | NDP | Catalase | 1.11.1.6 | 0.443 | |
| 1ld8 | U49 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.443 | |
| 1ohk | COP | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 1ry8 | RUT | Aldo-keto reductase family 1 member C3 | / | 0.443 | |
| 1yhj | R6C | Pyridoxal kinase | 2.7.1.35 | 0.443 | |
| 2vle | DZN | Aldehyde dehydrogenase, mitochondrial | 1.2.1.3 | 0.443 | |
| 2wu4 | HBP | Acetylcholinesterase | 3.1.1.7 | 0.443 | |
| 3ele | PLP | Aminotransferase | / | 0.443 | |
| 3g58 | 988 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.443 | |
| 3tfu | PL8 | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase | 2.6.1.62 | 0.443 | |
| 3ugr | IMN | Aldo-keto reductase family 1 member C3 | / | 0.443 | |
| 4a30 | QMI | Glycylpeptide N-tetradecanoyltransferase | / | 0.443 | |
| 4ky4 | 04J | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.443 | |
| 1qip | GNB | Lactoylglutathione lyase | 4.4.1.5 | 0.442 | |
| 2fap | RAD | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.442 | |
| 2fap | RAD | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.442 | |
| 2geu | COK | Pantothenate kinase | 2.7.1.33 | 0.442 | |
| 2hzq | STR | Apolipoprotein D | / | 0.442 | |
| 2vt4 | P32 | Beta-1 adrenergic receptor | / | 0.442 | |
| 3af0 | GDP | Pantothenate kinase | 2.7.1.33 | 0.442 | |
| 3b9o | FMN | Alkane monoxygenase | / | 0.442 | |
| 3d2d | REN | Reticuline oxidase | 1.21.3.3 | 0.442 | |
| 3r7m | SUZ | Aldo-keto reductase family 1 member C3 | / | 0.442 | |
| 3ny8 | JRZ | Beta-2 adrenergic receptor | / | 0.442 | |
| 1jum | BER | HTH-type transcriptional regulator QacR | / | 0.441 | |
| 1ndz | FR5 | Adenosine deaminase | 3.5.4.4 | 0.441 | |
| 1ps9 | MDE | 2,4-dienoyl-CoA reductase | 1.3.1.34 | 0.441 | |
| 1so2 | 666 | cGMP-inhibited 3',5'-cyclic phosphodiesterase B | 3.1.4.17 | 0.441 | |
| 2c1z | KMP | Anthocyanidin 3-O-glucosyltransferase 2 | 2.4.1.115 | 0.441 | |
| 2jf0 | HBP | Acetylcholinesterase | 3.1.1.7 | 0.441 | |
| 2pdw | FID | Aldose reductase | 1.1.1.21 | 0.441 | |
| 2vdy | HCY | Corticosteroid-binding globulin | / | 0.441 | |
| 3cv7 | C2U | Alcohol dehydrogenase [NADP(+)] | 1.1.1.2 | 0.441 | |
| 3o73 | O73 | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.441 | |
| 3ug8 | IMN | Aldo-keto reductase family 1 member C3 | / | 0.441 | |
| 4jq2 | SUZ | Aldo-keto reductase family 1 member C2 | / | 0.441 | |
| 4jqa | ID8 | Aldo-keto reductase family 1 member C2 | / | 0.441 | |
| 3uon | QNB | Muscarinic acetylcholine receptor M2 | / | 0.441 | |
| 1dgh | NDP | Catalase | 1.11.1.6 | 0.440 | |
| 1eve | E20 | Acetylcholinesterase | 3.1.1.7 | 0.440 | |
| 1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
| 1w6j | R71 | Lanosterol synthase | 5.4.99.7 | 0.440 | |
| 2acl | L05 | Oxysterols receptor LXR-alpha | / | 0.440 | |
| 2w6c | BM4 | Acetylcholinesterase | 3.1.1.7 | 0.440 | |
| 2y60 | M8F | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
| 2zs9 | ADP | Pantothenate kinase | 2.7.1.33 | 0.440 | |
| 2zsb | ADP | Pantothenate kinase | 2.7.1.33 | 0.440 | |
| 3qpn | PFK | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.440 | |
| 4b7z | Q4Q | Acetylcholinesterase | 3.1.1.7 | 0.440 | |
| 4bfy | ZVY | Pantothenate kinase | 2.7.1.33 | 0.440 | |
| 4e90 | 7RG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.440 | |
| 4qg1 | DTP | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.440 | |
| 8cat | NDP | Catalase | 1.11.1.6 | 0.440 |