sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2dux | ZST | Aldose reductase | 1.1.1.21 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 2dux | ZST | Aldose reductase | 1.1.1.21 | 1.000 | |
| 2duz | ZST | Aldose reductase | 1.1.1.21 | 0.806 | |
| 2i17 | LDT | Aldose reductase | 1.1.1.21 | 0.768 | |
| 3ght | LDT | Aldose reductase | 1.1.1.21 | 0.747 | |
| 3ld5 | LDT | Aldose reductase | 1.1.1.21 | 0.747 | |
| 2pdg | 47D | Aldose reductase | 1.1.1.21 | 0.740 | |
| 1z3n | 3NA | Aldose reductase | 1.1.1.21 | 0.719 | |
| 3ghs | LDT | Aldose reductase | 1.1.1.21 | 0.716 | |
| 2hvo | ZST | Aldose reductase | 1.1.1.21 | 0.711 | |
| 3g5e | Q74 | Aldose reductase | 1.1.1.21 | 0.700 | |
| 3ghr | LDT | Aldose reductase | 1.1.1.21 | 0.700 | |
| 3ghu | LDT | Aldose reductase | 1.1.1.21 | 0.699 | |
| 3m4h | 388 | Aldose reductase | 1.1.1.21 | 0.699 | |
| 1t40 | ID5 | Aldose reductase | 1.1.1.21 | 0.698 | |
| 4yu1 | 53N | Aldose reductase | 1.1.1.21 | 0.694 | |
| 2pdi | ZST | Aldose reductase | 1.1.1.21 | 0.689 | |
| 2i16 | LDT | Aldose reductase | 1.1.1.21 | 0.685 | |
| 3lbo | LDT | Aldose reductase | 1.1.1.21 | 0.685 | |
| 2qxw | LDT | Aldose reductase | 1.1.1.21 | 0.677 | |
| 3mb9 | ZST | Aldose reductase | 1.1.1.21 | 0.672 | |
| 3lql | LDT | Aldose reductase | 1.1.1.21 | 0.671 | |
| 1pwl | BFI | Aldose reductase | 1.1.1.21 | 0.669 | |
| 4gca | 2X9 | Aldose reductase | 1.1.1.21 | 0.657 | |
| 3len | ZST | Aldose reductase | 1.1.1.21 | 0.651 | |
| 1t41 | ID5 | Aldose reductase | 1.1.1.21 | 0.649 | |
| 1us0 | LDT | Aldose reductase | 1.1.1.21 | 0.648 | |
| 2pdn | 47D | Aldose reductase | 1.1.1.21 | 0.647 | |
| 2pdp | 393 | Aldose reductase | 1.1.1.21 | 0.647 | |
| 2pdx | ZST | Aldose reductase | 1.1.1.21 | 0.647 | |
| 2pzn | 393 | Aldose reductase | 1.1.1.21 | 0.647 | |
| 2iki | 388 | Aldose reductase | 1.1.1.21 | 0.641 | |
| 2pdm | ZST | Aldose reductase | 1.1.1.21 | 0.627 | |
| 2pdc | 393 | Aldose reductase | 1.1.1.21 | 0.625 | |
| 2pdh | 47D | Aldose reductase | 1.1.1.21 | 0.624 | |
| 2pdu | 393 | Aldose reductase | 1.1.1.21 | 0.624 | |
| 3t42 | 3T4 | Aldose reductase | 1.1.1.21 | 0.624 | |
| 2pd5 | ZST | Aldose reductase | 1.1.1.21 | 0.621 | |
| 2pdb | ZST | Aldose reductase | 1.1.1.21 | 0.618 | |
| 3m0i | ZST | Aldose reductase | 1.1.1.21 | 0.618 | |
| 3m64 | 393 | Aldose reductase | 1.1.1.21 | 0.618 | |
| 2pdf | ZST | Aldose reductase | 1.1.1.21 | 0.612 | |
| 1z89 | 62P | Aldose reductase | 1.1.1.21 | 0.607 | |
| 2dv0 | ZST | Aldose reductase | 1.1.1.21 | 0.606 | |
| 2fz8 | ZST | Aldose reductase | 1.1.1.21 | 0.606 | |
| 3mc5 | 393 | Aldose reductase | 1.1.1.21 | 0.603 | |
| 2pdq | 47D | Aldose reductase | 1.1.1.21 | 0.596 | |
| 2ikj | 393 | Aldose reductase | 1.1.1.21 | 0.595 | |
| 2hv5 | ZST | Aldose reductase | 1.1.1.21 | 0.594 | |
| 1frb | ZST | Aldose reductase-related protein 2 | / | 0.592 | |
| 2ikh | LIT | Aldose reductase | 1.1.1.21 | 0.591 | |
| 2hvn | ZST | Aldose reductase | 1.1.1.21 | 0.589 | |
| 2pdj | 393 | Aldose reductase | 1.1.1.21 | 0.584 | |
| 2fz9 | ZST | Aldose reductase | 1.1.1.21 | 0.571 | |
| 1ah3 | TOL | Aldose reductase | 1.1.1.21 | 0.570 | |
| 1el3 | I84 | Aldose reductase | 1.1.1.21 | 0.569 | |
| 1iei | ZES | Aldose reductase | 1.1.1.21 | 0.565 | |
| 3lz5 | LDT | Aldose reductase | 1.1.1.21 | 0.565 | |
| 1zua | TOL | Aldo-keto reductase family 1 member B10 | 1.1.1 | 0.556 | |
| 2pdl | TOL | Aldose reductase | 1.1.1.21 | 0.554 | |
| 2fzd | TOL | Aldose reductase | 1.1.1.21 | 0.539 | |
| 2fzb | TOL | Aldose reductase | 1.1.1.21 | 0.510 | |
| 5liu | 388 | Aldo-keto reductase family 1 member B10 | 1.1.1 | 0.509 | |
| 2pdk | SBI | Aldose reductase | 1.1.1.21 | 0.501 | |
| 1q9m | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.496 | |
| 2fm5 | M99 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.494 | |
| 4b13 | X25 | Glycylpeptide N-tetradecanoyltransferase | / | 0.494 | |
| 4kn1 | 04J | Folate receptor beta | / | 0.494 | |
| 2jf0 | HBP | Acetylcholinesterase | 3.1.1.7 | 0.492 | |
| 4dbw | 511 | Aldo-keto reductase family 1 member C3 | / | 0.491 | |
| 1tbb | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.490 | |
| 2agt | FID | Aldose reductase | 1.1.1.21 | 0.490 | |
| 1e1f | PSG | 4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase 1, chloroplastic | 3.2.1.182 | 0.489 | |
| 2xuj | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.489 | |
| 4b12 | C23 | Glycylpeptide N-tetradecanoyltransferase | / | 0.489 | |
| 4pab | THG | Dimethylglycine dehydrogenase, mitochondrial | 1.5.8.4 | 0.489 | |
| 1tco | FK5 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.486 | |
| 1tco | FK5 | Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform | 3.1.3.16 | 0.486 | |
| 4kmz | FOL | Folate receptor beta | / | 0.486 | |
| 4b11 | 7I1 | Glycylpeptide N-tetradecanoyltransferase | / | 0.485 | |
| 1xoq | ROF | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.484 | |
| 2aov | C2M | Histamine N-methyltransferase | 2.1.1.8 | 0.484 | |
| 2iqd | LPA | Aldose reductase | 1.1.1.21 | 0.484 | |
| 1uho | VDN | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.483 | |
| 3ghv | GHC | Dihydrofolate reductase | 1.5.1.3 | 0.483 | |
| 4fam | 0SZ | Aldo-keto reductase family 1 member C3 | / | 0.483 | |
| 2aot | 2PM | Histamine N-methyltransferase | 2.1.1.8 | 0.482 | |
| 2yne | YNE | Glycylpeptide N-tetradecanoyltransferase | / | 0.482 | |
| 2vt4 | P32 | Beta-1 adrenergic receptor | / | 0.481 | |
| 3k4s | 0MO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.481 | |
| 4dbu | BT9 | Aldo-keto reductase family 1 member C3 | / | 0.481 | |
| 3g4g | D71 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.480 | |
| 2f38 | 15M | Aldo-keto reductase family 1 member C3 | / | 0.479 | |
| 4hf4 | 15H | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.479 | |
| 4wev | SUZ | Aldo-keto reductase family 1 member B10 | 1.1.1 | 0.479 | |
| 8cat | NDP | Catalase | 1.11.1.6 | 0.479 | |
| 2xuf | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.478 | |
| 3n0h | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.478 | |
| 4kn2 | LYA | Folate receptor beta | / | 0.478 | |
| 1oyn | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.477 | |
| 4eil | FOL | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.477 | |
| 2cbq | TH2 | Neocarzinostatin | / | 0.476 | |
| 4phl | PIL | Phosphodiesterase | / | 0.476 | |
| 4li6 | 1XO | Tankyrase-1 | 2.4.2.30 | 0.475 | |
| 3g4k | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.474 | |
| 4bbh | YBN | Glycylpeptide N-tetradecanoyltransferase | / | 0.474 | |
| 4mm7 | 29J | Na(+):neurotransmitter symporter (Snf family) | / | 0.473 | |
| 1ry0 | PG2 | Aldo-keto reductase family 1 member C3 | / | 0.472 | |
| 2psj | CEI | Renilla-luciferin 2-monooxygenase | 1.13.12.5 | 0.472 | |
| 2v0m | KLN | Cytochrome P450 3A4 | / | 0.472 | |
| 3d3p | 20A | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.472 | |
| 3g58 | 988 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.472 | |
| 1efy | BZC | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.471 | |
| 1ro6 | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.471 | |
| 3w5e | NVW | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.471 | |
| 4mvh | 2F5 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.471 | |
| 1xf0 | ASD | Aldo-keto reductase family 1 member C3 | / | 0.470 | |
| 2cek | N8T | Acetylcholinesterase | 3.1.1.7 | 0.470 | |
| 3g4l | ROF | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.470 | |
| 1h35 | R01 | Squalene--hopene cyclase | 4.2.1.129 | 0.469 | |
| 1p91 | SAM | 23S rRNA (guanine(745)-N(1))-methyltransferase | / | 0.469 | |
| 1pqc | 444 | Oxysterols receptor LXR-beta | / | 0.469 | |
| 1y2k | 7DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.469 | |
| 3f3y | 4OA | Bile salt sulfotransferase | 2.8.2.14 | 0.468 | |
| 4paa | THG | Dimethylglycine dehydrogenase, mitochondrial | 1.5.8.4 | 0.468 | |
| 3g4i | D71 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.467 | |
| 3hxe | BD8 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.467 | |
| 3u2c | SUZ | Aldose reductase | 1.1.1.21 | 0.467 | |
| 4ky4 | 04J | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.467 | |
| 1o5r | FR9 | Adenosine deaminase | 3.5.4.4 | 0.466 | |
| 2f2k | TGG | Aldose reductase | 1.1.1.21 | 0.466 | |
| 3gsi | THG | Dimethylglycine oxidase | 1.5.3.10 | 0.466 | |
| 2w6c | BM4 | Acetylcholinesterase | 3.1.1.7 | 0.465 | |
| 2wey | EV1 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.465 | |
| 2xup | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.465 | |
| 3iak | EV1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.465 | |
| 4bjb | P34 | Tankyrase-2 | 2.4.2.30 | 0.465 | |
| 4ey7 | E20 | Acetylcholinesterase | 3.1.1.7 | 0.465 | |
| 1y2c | 3DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.464 | |
| 2bjs | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.464 | |
| 2inz | OHP | Aldose reductase | 1.1.1.21 | 0.464 | |
| 3n3z | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.464 | |
| 1xon | PIL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.463 | |
| 1zgc | A2E | Acetylcholinesterase | 3.1.1.7 | 0.462 | |
| 2pd9 | FID | Aldose reductase | 1.1.1.21 | 0.462 | |
| 3t0k | DCQ | Sulfide-quinone reductase | / | 0.462 | |
| 4u16 | 3C0 | Muscarinic acetylcholine receptor M3 | / | 0.462 | |
| 1mkd | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.461 | |
| 1uhj | CZB | Aequorin-2 | / | 0.461 | |
| 1xom | CIO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.461 | |
| 3fap | ARD | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.461 | |
| 3fap | ARD | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.461 | |
| 3keg | MRE | FMN-dependent NADH-azoreductase 1 | / | 0.461 | |
| 3ox2 | 79X | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.461 | |
| 1pj6 | FOL | Dimethylglycine oxidase | 1.5.3.10 | 0.460 | |
| 2o8h | 227 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.460 | |
| 4x3u | SVR | Chromobox protein homolog 7 | / | 0.460 | |
| 1ah0 | SBI | Aldose reductase | 1.1.1.21 | 0.459 | |
| 2i65 | NAD | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.459 | |
| 3hii | PNT | Amiloride-sensitive amine oxidase [copper-containing] | / | 0.459 | |
| 4ara | C56 | Acetylcholinesterase | 3.1.1.7 | 0.459 | |
| 4kn0 | MTX | Folate receptor beta | / | 0.459 | |
| 1ihi | IU5 | Aldo-keto reductase family 1 member C2 | / | 0.458 | |
| 3g49 | 3G4 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.458 | |
| 3hgg | CHD | CmeR | / | 0.458 | |
| 3jsx | CC2 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.458 | |
| 3uwe | VJJ | Aldo-keto reductase family 1 member C3 | / | 0.458 | |
| 3v94 | WYQ | Phosphodiesterase | / | 0.458 | |
| 4c1i | EH9 | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.458 | |
| 4m0f | 1YK | Acetylcholinesterase | 3.1.1.7 | 0.458 | |
| 4muw | 2F4 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.458 | |
| 4myq | 19T | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.458 | |
| 1eko | I84 | Aldose reductase | 1.1.1.21 | 0.457 | |
| 1zkn | IBM | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.457 | |
| 3q9b | B3N | Acetylpolyamine amidohydrolase | / | 0.457 | |
| 4bft | ZVT | Pantothenate kinase | 2.7.1.33 | 0.457 | |
| 4jsr | 1NQ | NAD-dependent protein deacetylase sirtuin-3, mitochondrial | 3.5.1 | 0.457 | |
| 4lrh | FOL | Folate receptor alpha | / | 0.457 | |
| 2nmt | MIM | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.456 | |
| 4c2z | 646 | Glycylpeptide N-tetradecanoyltransferase 1 | / | 0.456 | |
| 4kp6 | 1S1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.456 | |
| 4tvj | 09L | Poly [ADP-ribose] polymerase 2 | 2.4.2.30 | 0.456 | |
| 1qv0 | CZH | Obelin | / | 0.455 | |
| 2fm0 | M98 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.455 | |
| 3aiq | HBO | 4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase 1b, chloroplastic | 3.2.1.182 | 0.455 | |
| 3hxd | BD7 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.455 | |
| 3v35 | NTI | Aldose reductase | 1.1.1.21 | 0.455 | |
| 4a95 | 9MT | Glycylpeptide N-tetradecanoyltransferase | / | 0.455 | |
| 1kyv | RBF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.454 | |
| 1kyx | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.454 | |
| 1pj7 | FFO | Dimethylglycine oxidase | 1.5.3.10 | 0.454 | |
| 1tfz | 869 | 4-hydroxyphenylpyruvate dioxygenase | 1.13.11.27 | 0.454 | |
| 1y2b | DEE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.454 | |
| 2ouu | 35G | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.454 | |
| 2pdy | FID | Aldose reductase | 1.1.1.21 | 0.454 | |
| 2xuh | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.454 | |
| 1jqd | SAH | Histamine N-methyltransferase | 2.1.1.8 | 0.453 | |
| 1s36 | CEI | Obelin | / | 0.453 | |
| 3uzx | AOM | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.453 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.453 | |
| 4kq6 | DLZ | 6,7-dimethyl-8-ribityllumazine synthase | / | 0.453 | |
| 1xor | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.452 | |
| 1y2e | 5DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.452 | |
| 1zkl | IBM | High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A | 3.1.4.53 | 0.452 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.452 | |
| 3r8h | ZOM | Aldo-keto reductase family 1 member C3 | / | 0.452 | |
| 3uzz | TES | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.452 | |
| 4mrx | CZH | Obelin | / | 0.452 | |
| 1fap | RAP | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.451 | |
| 1fap | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.451 | |
| 1ro9 | 8BR | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.451 | |
| 1udt | VIA | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.451 | |
| 1zgb | A1E | Acetylcholinesterase | 3.1.1.7 | 0.451 | |
| 2d06 | EST | Sulfotransferase 1A1 | 2.8.2.1 | 0.451 | |
| 3c1o | NAP | Eugenol synthase | / | 0.451 | |
| 3o56 | ZG1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.451 | |
| 4bj9 | UHB | Tankyrase-2 | 2.4.2.30 | 0.451 | |
| 1ry8 | RUT | Aldo-keto reductase family 1 member C3 | / | 0.450 | |
| 1t47 | NTD | 4-hydroxyphenylpyruvate dioxygenase | 1.13.11.27 | 0.450 | |
| 2rcw | AAI | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.450 | |
| 3cas | ASD | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.450 | |
| 3cr7 | PPS | Adenylyl-sulfate kinase | 2.7.1.25 | 0.450 | |
| 3r43 | ID8 | Aldo-keto reductase family 1 member C3 | / | 0.450 | |
| 3u57 | DH8 | Raucaffricine-O-beta-D-glucosidase | 3.2.1.125 | 0.450 | |
| 3ug8 | IMN | Aldo-keto reductase family 1 member C3 | / | 0.450 | |
| 3ny8 | JRZ | Beta-2 adrenergic receptor | / | 0.450 | |
| 1u65 | CP0 | Acetylcholinesterase | 3.1.1.7 | 0.449 | |
| 2ea4 | F79 | Methionine aminopeptidase 2 | / | 0.449 | |
| 2is7 | 2CL | Aldose reductase | 1.1.1.21 | 0.449 | |
| 4b14 | 4XB | Glycylpeptide N-tetradecanoyltransferase | / | 0.449 | |
| 4ga8 | SBI | Aldo-keto reductase family 1 member B10 | 1.1.1 | 0.449 | |
| 1i5r | HYC | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.448 | |
| 1pd9 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 1ut6 | A8N | Acetylcholinesterase | 3.1.1.7 | 0.448 | |
| 2ckm | AA7 | Acetylcholinesterase | 3.1.1.7 | 0.448 | |
| 2gyw | OBI | Acetylcholinesterase | 3.1.1.7 | 0.448 | |
| 2hzq | STR | Apolipoprotein D | / | 0.448 | |
| 2r2g | EMF | Eugenol synthase 1 | 1.1.1.318 | 0.448 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.448 | |
| 3b82 | NAD | Exotoxin A | 2.4.2.36 | 0.448 | |
| 3tfj | THG | Dimethylsulfonioproprionate demethylase DmdA | 2.1.1.269 | 0.448 | |
| 3zec | ANP | Adenosine monophosphate-protein transferase SoFic | 2.7.7.n1 | 0.448 | |
| 4a32 | 2CD | Glycylpeptide N-tetradecanoyltransferase | / | 0.448 | |
| 4n1f | CZH | Obelin | / | 0.448 | |
| 1dgb | NDP | Catalase | 1.11.1.6 | 0.447 | |
| 1o6q | R17 | Squalene--hopene cyclase | 4.2.1.129 | 0.447 | |
| 1p0p | BCH | Cholinesterase | 3.1.1.8 | 0.447 | |
| 1q23 | FUA | Chloramphenicol acetyltransferase | 2.3.1.28 | 0.447 | |
| 1s2c | FLF | Aldo-keto reductase family 1 member C3 | / | 0.447 | |
| 2f98 | NGV | Aklanonic acid methyl ester cyclase AcmA | 5.5.1.23 | 0.447 | |
| 2fzj | DH3 | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 2xui | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.447 | |
| 3nhp | HGZ | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.447 | |
| 3t31 | DCQ | Sulfide-quinone reductase | / | 0.447 | |
| 3vf6 | 0H6 | Glucokinase | 2.7.1.2 | 0.447 | |
| 4bfy | ZVY | Pantothenate kinase | 2.7.1.33 | 0.447 | |
| 5cxv | 0HK | Muscarinic acetylcholine receptor M1 | / | 0.447 | |
| 2ouy | CMP | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.446 | |
| 2xuk | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.446 | |
| 2y1w | 849 | Histone-arginine methyltransferase CARM1 | / | 0.446 | |
| 3hyw | DCQ | Sulfide-quinone reductase | / | 0.446 | |
| 3qpo | PFR | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.446 | |
| 3szf | DCQ | Sulfide-quinone reductase | / | 0.446 | |
| 4bvn | P32 | Beta-1 adrenergic receptor | / | 0.446 | |
| 4gvs | F4M | Methenyltetrahydromethanopterin cyclohydrolase | 3.5.4.27 | 0.446 | |
| 4ia0 | 5BB | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.446 | |
| 5d5a | CAU | Beta-2 adrenergic receptor | / | 0.446 | |
| 1kyy | INI | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.445 | |
| 1y2d | 4DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.445 | |
| 1z4i | UMP | 5'(3')-deoxyribonucleotidase, mitochondrial | 3.1.3 | 0.445 | |
| 3aos | JH2 | Hemolymph juvenile hormone binding protein | / | 0.445 | |
| 3gx9 | TXD | Morphinone reductase | / | 0.445 | |
| 3o73 | O73 | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.445 | |
| 3wav | DWV | Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 | 3.1.4.39 | 0.445 | |
| 4b7z | Q4Q | Acetylcholinesterase | 3.1.1.7 | 0.445 | |
| 4lcn | GNG | Cytidine and deoxycytidylate deaminase zinc-binding region | / | 0.445 | |
| 1mvt | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 1w6j | R71 | Lanosterol synthase | 5.4.99.7 | 0.444 | |
| 2cmf | F11 | Acetylcholinesterase | 3.1.1.7 | 0.444 | |
| 2y0j | AXC | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.444 | |
| 3itu | IBM | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.444 | |
| 4ajd | F04 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.444 | |
| 4drh | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.444 | |
| 4drh | RAP | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.444 | |
| 4gn6 | TYL | Lactoperoxidase | 1.11.1.7 | 0.444 | |
| 5std | UNN | Scytalone dehydratase | 4.2.1.94 | 0.444 | |
| 2y04 | 68H | Beta-1 adrenergic receptor | / | 0.444 | |
| 4e0u | 0MV | Cyclic dipeptide N-prenyltransferase | / | 0.443 | |
| 4h7c | 10H | Aldo-keto reductase family 1 member C3 | / | 0.443 | |
| 4hyf | 1AK | Tankyrase-2 | 2.4.2.30 | 0.443 | |
| 4jt8 | 1NR | NAD-dependent protein deacetylase sirtuin-3, mitochondrial | 3.5.1 | 0.443 | |
| 4kfj | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 1blz | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
| 1dtp | APU | Diphtheria toxin | / | 0.442 | |
| 1soj | IBM | cGMP-inhibited 3',5'-cyclic phosphodiesterase B | 3.1.4.17 | 0.442 | |
| 2aot | SAH | Histamine N-methyltransferase | 2.1.1.8 | 0.442 | |
| 2b04 | CHO | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.442 | |
| 2xuq | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.442 | |
| 2zit | NAD | Exotoxin A | 2.4.2.36 | 0.442 | |
| 3nub | UD0 | UDP-2-acetamido-2-deoxy-3-oxo-D-glucuronate aminotransferase | 2.6.1.98 | 0.442 | |
| 3o57 | ZG2 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.442 | |
| 3u9f | CLM | Chloramphenicol acetyltransferase | 2.3.1.28 | 0.442 | |
| 3zht | TD9 | Multifunctional 2-oxoglutarate metabolism enzyme | 1.2.4.2 | 0.442 | |
| 4a4x | JUP | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.442 | |
| 4f1l | 0RY | Poly [ADP-ribose] polymerase 14 | 2.4.2.30 | 0.442 | |
| 4fal | 0T0 | Aldo-keto reductase family 1 member C3 | / | 0.442 | |
| 4jq1 | NPS | Aldo-keto reductase family 1 member C2 | / | 0.442 | |
| 4kak | 06U | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 4mm4 | 8PR | Na(+):neurotransmitter symporter (Snf family) | / | 0.442 | |
| 4qa0 | SHH | Histone deacetylase 8 | 3.5.1.98 | 0.442 | |
| 4wlj | IK2 | Kynurenine--oxoglutarate transaminase 1 | 2.6.1.7 | 0.442 | |
| 4xwt | U5P | Ribonuclease J | / | 0.442 | |
| 1o6r | R19 | Squalene--hopene cyclase | 4.2.1.129 | 0.441 | |
| 1rvv | INI | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.441 | |
| 1w4l | GL8 | Acetylcholinesterase | 3.1.1.7 | 0.441 | |
| 1zq5 | E04 | Aldo-keto reductase family 1 member C3 | / | 0.441 | |
| 2b01 | TUD | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.441 | |
| 3biz | 61E | Wee1-like protein kinase | 2.7.10.2 | 0.441 | |
| 3hmv | HBT | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.441 | |
| 3s3v | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 3tvx | PNX | cAMP-specific 3',5'-cyclic phosphodiesterase 4A | 3.1.4.53 | 0.441 | |
| 3u5y | SCG | Raucaffricine-O-beta-D-glucosidase | 3.2.1.125 | 0.441 | |
| 4fa3 | 0SL | Aldo-keto reductase family 1 member C3 | / | 0.441 | |
| 4i5x | FLF | Aldo-keto reductase family 1 member B10 | 1.1.1 | 0.441 | |
| 4lxj | LAN | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.441 | |
| 5cc9 | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 4u14 | 0HK | Muscarinic acetylcholine receptor M3 | / | 0.441 | |
| 1odc | A8B | Acetylcholinesterase | 3.1.1.7 | 0.440 | |
| 1rkw | PNT | HTH-type transcriptional regulator QacR | / | 0.440 | |
| 1y60 | H4M | 5,6,7,8-tetrahydromethanopterin hydro-lyase | 4.2.1.147 | 0.440 | |
| 2i02 | FMN | Pyridoxamine 5'-phosphate oxidase-related, FMN-binding | / | 0.440 | |
| 2y6f | M9F | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
| 3akn | 11D | Fatty acid-binding protein, intestinal | / | 0.440 | |
| 3sni | 546 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.440 | |
| 4dbs | 0HV | Aldo-keto reductase family 1 member C3 | / | 0.440 | |
| 4hmn | 16J | Aldo-keto reductase family 1 member C3 | / | 0.440 | |
| 4jpg | 1OX | Pyruvate kinase PKM | 2.7.1.40 | 0.440 | |
| 4lsa | BLD | Protein BRASSINOSTEROID INSENSITIVE 1 | 2.7.10.1 | 0.440 | |
| 4mm9 | FVX | Na(+):neurotransmitter symporter (Snf family) | / | 0.440 |