sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2ble | 5GP | GMP reductase 1 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 2ble | 5GP | GMP reductase 1 | / | 1.000 | |
| 2bwg | 5GP | GMP reductase 1 | / | 0.641 | |
| 1nf7 | RVP | Inosine-5'-monophosphate dehydrogenase 2 | / | 0.535 | |
| 2cu0 | XMP | Inosine-5'-monophosphate dehydrogenase | / | 0.523 | |
| 1me7 | RVP | Inosine-5'-monophosphate dehydrogenase | / | 0.516 | |
| 4qq3 | XMP | Inosine-5'-monophosphate dehydrogenase | / | 0.511 | |
| 1me8 | RVP | Inosine-5'-monophosphate dehydrogenase | / | 0.506 | |
| 2a7r | 5GP | GMP reductase 2 | / | 0.497 | |
| 3kjr | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.497 | |
| 4dpw | AGS | Mevalonate diphosphate decarboxylase | / | 0.497 | |
| 2fy5 | SOP | Choline O-acetyltransferase | 2.3.1.6 | 0.493 | |
| 2om9 | AJA | Peroxisome proliferator-activated receptor gamma | / | 0.481 | |
| 1u7t | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.477 | |
| 2ou2 | ACO | Histone acetyltransferase KAT5 | / | 0.476 | |
| 4fn4 | NAD | Short chain dehydrogenase | / | 0.476 | |
| 2xaa | NAD | Secondary alcohol dehydrogenase | / | 0.475 | |
| 1mg5 | NAI | Alcohol dehydrogenase | 1.1.1.1 | 0.474 | |
| 2p5u | NAD | UDP-glucose 4-epimerase | / | 0.474 | |
| 2fzw | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.473 | |
| 1civ | NAP | Malate dehydrogenase [NADP], chloroplastic | 1.1.1.82 | 0.472 | |
| 1k6c | MK1 | Gag-Pol polyprotein | 3.4.23.16 | 0.471 | |
| 1y0s | 331 | Peroxisome proliferator-activated receptor delta | / | 0.471 | |
| 2qnq | QN3 | Gag-Pol polyprotein | 3.4.23.16 | 0.471 | |
| 4bcr | WY1 | Peroxisome proliferator-activated receptor alpha | / | 0.471 | |
| 3tox | NAP | Putative oxidoreductase | / | 0.470 | |
| 1u4o | NDD | L-lactate dehydrogenase | 1.1.1.27 | 0.469 | |
| 2o23 | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.469 | |
| 4z87 | 5GP | Inosine-5'-monophosphate dehydrogenase | / | 0.469 | |
| 1szm | BI4 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.468 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.468 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.466 | |
| 2gmh | FAD | Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial | 1.5.5.1 | 0.466 | |
| 2gs7 | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.465 | |
| 3nwx | KVS | Gag-Pol polyprotein | 3.4.23.16 | 0.465 | |
| 4fc7 | NAP | Peroxisomal 2,4-dienoyl-CoA reductase | 1.3.1.34 | 0.464 | |
| 4gh5 | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.464 | |
| 5kjc | NAJ | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.464 | |
| 3w0g | W07 | Vitamin D3 receptor | / | 0.463 | |
| 1z7y | AA5 | Cysteine synthase 1 | 2.5.1.47 | 0.462 | |
| 2x0r | NAD | Malate dehydrogenase | / | 0.462 | |
| 3bgb | LJG | Gag-Pol polyprotein | 3.4.23.16 | 0.461 | |
| 3dhe | AND | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.461 | |
| 3kjs | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.461 | |
| 3ndr | NAD | Pyridoxal 4-dehydrogenase | 1.1.1.107 | 0.461 | |
| 3oqu | A8S | Abscisic acid receptor PYL9 | / | 0.461 | |
| 3clb | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.460 | |
| 1mei | XMP | Inosine-5'-monophosphate dehydrogenase | / | 0.459 | |
| 3e8e | G98 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.459 | |
| 4qi4 | FAD | Cellobiose dehydrogenase | / | 0.459 | |
| 4xd2 | NAI | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.459 | |
| 3ea4 | FAB | Acetolactate synthase, chloroplastic | 2.2.1.6 | 0.458 | |
| 3g49 | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.458 | |
| 3rj9 | NAD | Alcohol dehydrogenase | 1.1.1.1 | 0.458 | |
| 4fj0 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.458 | |
| 1qbg | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.457 | |
| 2ooy | ATP | 5'-AMP-activated protein kinase subunit gamma | / | 0.457 | |
| 2yyu | C5P | Orotidine 5'-phosphate decarboxylase | / | 0.457 | |
| 3dga | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.457 | |
| 3uoz | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.457 | |
| 3vfq | AR6 | Poly [ADP-ribose] polymerase 14 | 2.4.2.30 | 0.457 | |
| 4ntd | FAD | Thioredoxin reductase | / | 0.457 | |
| 1mja | COA | Histone acetyltransferase ESA1 | / | 0.456 | |
| 1xe5 | 5FE | Plasmepsin-2 | 3.4.23.39 | 0.456 | |
| 3g7j | GTX | Glutathione transferase GST1-4 | / | 0.456 | |
| 3hja | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.456 | |
| 3vt7 | VDX | Vitamin D3 receptor | / | 0.456 | |
| 1g0n | NDP | Tetrahydroxynaphthalene reductase | 1.1.1.252 | 0.455 | |
| 1kf6 | FAD | Fumarate reductase flavoprotein subunit | 1.3.5.4 | 0.455 | |
| 2fzn | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.455 | |
| 4dc1 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.455 | |
| 1e6w | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.454 | |
| 1pdh | FAS | p-hydroxybenzoate hydroxylase | / | 0.454 | |
| 2a1y | 5GP | GMP reductase | / | 0.454 | |
| 4a6b | QG8 | Gag-Pol polyprotein | 3.4.23.16 | 0.454 | |
| 1iy8 | NAD | Levodione reductase | / | 0.453 | |
| 1s22 | ATP | Actin, alpha skeletal muscle | / | 0.453 | |
| 2bel | CBO | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.453 | |
| 2eba | FAD | Putative glutaryl-CoA dehydrogenase | / | 0.453 | |
| 2p41 | SAH | Genome polyprotein | / | 0.453 | |
| 3dme | FAD | Putative conserved exported protein | / | 0.453 | |
| 3i59 | N6R | CRP-like cAMP-activated global transcriptional regulator | / | 0.453 | |
| 3qwf | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.453 | |
| 3w9r | A8S | Abscisic acid receptor PYL9 | / | 0.453 | |
| 4iqg | NAP | Short-chain dehydrogenase/reductase SDR | / | 0.453 | |
| 4nxw | ADP | Mitochondrial dynamics protein MID51 | / | 0.453 | |
| 5cae | COA | Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial | 6.2.1.4 | 0.453 | |
| 1k6t | XN1 | Gag-Pol polyprotein | 3.4.23.16 | 0.452 | |
| 1llz | FMN | Ferredoxin-dependent glutamate synthase 2 | 1.4.7.1 | 0.452 | |
| 1tj2 | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.452 | |
| 2qo5 | CHD | Fatty acid-binding protein 10-A, liver basic | / | 0.452 | |
| 3iae | D7K | Benzaldehyde lyase | / | 0.452 | |
| 4g3j | VNT | Lanosterol 14-alpha-demethylase | / | 0.452 | |
| 4qec | NAP | ElxO | / | 0.452 | |
| 1jpa | ANP | Ephrin type-B receptor 2 | 2.7.10.1 | 0.451 | |
| 1kvk | ATP | Mevalonate kinase | 2.7.1.36 | 0.451 | |
| 1lwi | NAP | 3-alpha-hydroxysteroid dehydrogenase | 1.1.1.50 | 0.451 | |
| 1xq6 | NAP | Uncharacterized protein At5g02240 | / | 0.451 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.451 | |
| 3m12 | FAD | Monomeric sarcosine oxidase | 1.5.3.1 | 0.451 | |
| 3oib | FDA | Putative acyl-CoA dehydrogenase | / | 0.451 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.450 | |
| 3clr | FAD | Electron transfer flavoprotein subunit alpha | / | 0.450 | |
| 3cr3 | ADP | PTS-dependent dihydroxyacetone kinase, ADP-binding subunit DhaL | 2.7 | 0.450 | |
| 3nug | NAD | Pyridoxal 4-dehydrogenase | 1.1.1.107 | 0.450 | |
| 3zku | HCV | Isopenicillin N synthase | 1.21.3.1 | 0.450 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.450 | |
| 4a6c | QG9 | Gag-Pol polyprotein | 3.4.23.16 | 0.450 | |
| 4k42 | ADP | Actin, alpha skeletal muscle | / | 0.450 | |
| 5br7 | FAD | UDP-galactopyranose mutase | / | 0.450 | |
| 1gg5 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.449 | |
| 1k6v | XN2 | Gag-Pol polyprotein | 3.4.23.16 | 0.449 | |
| 1ma0 | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.449 | |
| 2f4b | EHA | Peroxisome proliferator-activated receptor gamma | / | 0.449 | |
| 3b70 | NAP | Enoyl reductase LovC | 1 | 0.449 | |
| 3k4c | FAD | Pyranose 2-oxidase | / | 0.449 | |
| 4i5e | NAP | Alclohol dehydrogenase/short-chain dehydrogenase | / | 0.449 | |
| 4qi5 | FAD | Cellobiose dehydrogenase | / | 0.449 | |
| 4zoh | MCN | Putative oxidoreductase molybdopterin-binding subunit | / | 0.449 | |
| 1rne | C60 | Renin | 3.4.23.15 | 0.448 | |
| 2cmj | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.448 | |
| 2rbe | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.448 | |
| 2ww4 | ADP | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | 2.7.1.148 | 0.448 | |
| 2y0m | ACO | Histone acetyltransferase KAT8 | / | 0.448 | |
| 3g1r | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.448 | |
| 3kq7 | KQ7 | Mitogen-activated protein kinase 14 | / | 0.448 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.448 | |
| 3mjh | GTP | Ras-related protein Rab-5A | / | 0.448 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.448 | |
| 3syi | FAD | Sulfide-quinone reductase | / | 0.448 | |
| 3vgl | ANP | Glucokinase | / | 0.448 | |
| 4d86 | ADP | Poly [ADP-ribose] polymerase 14 | 2.4.2.30 | 0.448 | |
| 5c6c | CMP | cGMP-dependent protein kinase 2 | 2.7.11.12 | 0.448 | |
| 1h5r | THM | Glucose-1-phosphate thymidylyltransferase 1 | / | 0.447 | |
| 1kqm | ANP | Myosin heavy chain, striated muscle | / | 0.447 | |
| 2hcd | BIV | Vitamin D3 receptor A | / | 0.447 | |
| 2wle | COA | Polysialic acid O-acetyltransferase | / | 0.447 | |
| 3a1n | NAD | NDP-sugar epimerase | / | 0.447 | |
| 3b4y | F42 | F420-dependent glucose-6-phosphate dehydrogenase | / | 0.447 | |
| 3t2z | FAD | Sulfide-quinone reductase | / | 0.447 | |
| 4yr9 | NAD | L-threonine 3-dehydrogenase, mitochondrial | 1.1.1.103 | 0.447 | |
| 1hf3 | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.446 | |
| 1men | GAR | Trifunctional purine biosynthetic protein adenosine-3 | 2.1.2.2 | 0.446 | |
| 1psa | 0ZL | Pepsin A | 3.4.23.1 | 0.446 | |
| 1teh | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.446 | |
| 2fy4 | COA | Choline O-acetyltransferase | 2.3.1.6 | 0.446 | |
| 3kgc | LY7 | Glutamate receptor 2 | / | 0.446 | |
| 3nxx | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 3r3s | NAD | Putative oxidoreductase | / | 0.446 | |
| 4ejm | NAP | Putative zinc-binding dehydrogenase | / | 0.446 | |
| 4z38 | FMN | MlnA | / | 0.446 | |
| 1d4c | FAD | Fumarate reductase flavoprotein subunit | 1.3.5.4 | 0.445 | |
| 1jq5 | NAD | Glycerol dehydrogenase | 1.1.1.6 | 0.445 | |
| 1l7e | NAI | NAD(P) transhydrogenase subunit alpha part 1 | 1.6.1.2 | 0.445 | |
| 1t7j | 478 | Gag-Pol polyprotein | 3.4.23.16 | 0.445 | |
| 2ft9 | CHD | Fatty acid-binding protein 2, liver | / | 0.445 | |
| 2giv | ACO | Histone acetyltransferase KAT8 | / | 0.445 | |
| 2zjm | F1M | Beta-secretase 1 | 3.4.23.46 | 0.445 | |
| 3etg | NDP | Glutamate dehydrogenase 1, mitochondrial | 1.4.1.3 | 0.445 | |
| 3oq6 | NAJ | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.445 | |
| 3r6s | CMP | CRP-like cAMP-activated global transcriptional regulator | / | 0.445 | |
| 3sz0 | FAD | Sulfide-quinone reductase | / | 0.445 | |
| 4jlo | ADP | Adenylate kinase | / | 0.445 | |
| 4kzo | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.445 | |
| 4nxu | ADP | Mitochondrial dynamics protein MID51 | / | 0.445 | |
| 4w5j | AP5 | Adenylate kinase | / | 0.445 | |
| 1ae1 | NAP | Tropinone reductase 1 | / | 0.444 | |
| 1cyd | NDP | Carbonyl reductase [NADPH] 2 | 1.1.1.184 | 0.444 | |
| 1dbv | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.444 | |
| 1f8f | NAD | Benzyl alcohol dehydrogenase | / | 0.444 | |
| 1hwz | NDP | Glutamate dehydrogenase 1, mitochondrial | 1.4.1.3 | 0.444 | |
| 1txi | TX5 | Vitamin D3 receptor | / | 0.444 | |
| 2c0c | NAP | Prostaglandin reductase 3 | 1 | 0.444 | |
| 2hdj | NDP | Aldo-keto reductase family 1 member C2 | / | 0.444 | |
| 2xx9 | 1NF | Glutamate receptor 2 | / | 0.444 | |
| 3q43 | D66 | M1 family aminopeptidase | 3.4.11 | 0.444 | |
| 3tqh | NDP | Quinone oxidoreductase | / | 0.444 | |
| 4bca | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.444 | |
| 4oh4 | ANP | Protein BRASSINOSTEROID INSENSITIVE 1 | 2.7.10.1 | 0.444 | |
| 1nqo | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.443 | |
| 1zq9 | SAM | Probable dimethyladenosine transferase | / | 0.443 | |
| 2b9w | FAD | Putative aminooxidase | / | 0.443 | |
| 2dte | NAI | Glucose 1-dehydrogenase related protein | / | 0.443 | |
| 2h8h | H8H | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.443 | |
| 2jn3 | JN3 | Fatty acid-binding protein, liver | / | 0.443 | |
| 3liv | E16 | Protease | / | 0.443 | |
| 4ydu | ADP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.443 | |
| 5idw | NAP | Short-chain dehydrogenase/reductase SDR | / | 0.443 | |
| 1bw9 | NAD | Phenylalanine dehydrogenase | / | 0.442 | |
| 1d4a | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.442 | |
| 1edo | NAP | 3-oxoacyl-[acyl-carrier-protein] reductase 1, chloroplastic | 1.1.1.100 | 0.442 | |
| 1f8w | FAD | NADH peroxidase | 1.11.1.1 | 0.442 | |
| 1ffu | FAD | Carbon monoxide dehydrogenase medium chain | / | 0.442 | |
| 1h69 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.442 | |
| 1h73 | ANP | Homoserine kinase | 2.7.1.39 | 0.442 | |
| 1k6p | XN3 | Gag-Pol polyprotein | 3.4.23.16 | 0.442 | |
| 1mp0 | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.442 | |
| 1o0s | NAI | NAD-dependent malic enzyme, mitochondrial | 1.1.1.38 | 0.442 | |
| 1t44 | ATP | Actin, alpha skeletal muscle | / | 0.442 | |
| 1w4z | NAP | Putative ketoacyl reductase | 1.3.1 | 0.442 | |
| 2cdu | FAD | NADH oxidase | / | 0.442 | |
| 2cft | PLP | Pyridoxal phosphate phosphatase | / | 0.442 | |
| 2ewm | NAD | (S)-1-Phenylethanol dehydrogenase | 1.1.1.311 | 0.442 | |
| 2tps | TPS | Thiamine-phosphate synthase | / | 0.442 | |
| 2yyi | FAD | 4-hydroxyphenylacetate 3-monooxygenase oxygenase component | 1.14.14.9 | 0.442 | |
| 3jv7 | NAD | Secondary alcohol dehydrogenase | / | 0.442 | |
| 3lu8 | IQX | Serum albumin | / | 0.442 | |
| 3qls | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 3rj5 | NAD | Alcohol dehydrogenase | 1.1.1.1 | 0.442 | |
| 3vrt | YS2 | Vitamin D3 receptor | / | 0.442 | |
| 3w0i | O11 | Vitamin D3 receptor | / | 0.442 | |
| 4fj1 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.442 | |
| 4jbi | NDP | Alcohol dehydrogenase (Zinc) | / | 0.442 | |
| 4yag | NAI | C alpha-dehydrogenase | / | 0.442 | |
| 5jyd | NAD | Short chain dehydrogenase | / | 0.442 | |
| 5mdh | NAD | Malate dehydrogenase, cytoplasmic | 1.1.1.37 | 0.442 | |
| 1c70 | L75 | Protease | / | 0.441 | |
| 1fxs | NAP | GDP-L-fucose synthase | / | 0.441 | |
| 1mjb | ACO | Histone acetyltransferase ESA1 | / | 0.441 | |
| 1pr9 | NAP | L-xylulose reductase | 1.1.1.10 | 0.441 | |
| 1rp0 | AHZ | Thiamine thiazole synthase, chloroplastic | / | 0.441 | |
| 1t7i | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.441 | |
| 1ybm | NAP | Uncharacterized protein At5g02240 | / | 0.441 | |
| 2gst | GPS | Glutathione S-transferase Mu 1 | 2.5.1.18 | 0.441 | |
| 2q4b | NAP | Uncharacterized protein At5g02240 | / | 0.441 | |
| 3i7e | DJR | Gag-Pol polyprotein | / | 0.441 | |
| 3iah | NAP | Putative oxoacyl-(Acyl carrier protein) reductase | / | 0.441 | |
| 3mvq | NDP | Glutamate dehydrogenase 1, mitochondrial | 1.4.1.3 | 0.441 | |
| 3poz | 03P | Epidermal growth factor receptor | 2.7.10.1 | 0.441 | |
| 3q44 | D50 | M1 family aminopeptidase | 3.4.11 | 0.441 | |
| 4g1z | 0VP | Vitamin D3 receptor A | / | 0.441 | |
| 4h8a | NAI | Ureidoglycolate dehydrogenase (NAD(+)) | 1.1.1.350 | 0.441 | |
| 4ia7 | BIV | Vitamin D3 receptor A | / | 0.441 | |
| 4ite | TEY | Vitamin D3 receptor | / | 0.441 | |
| 4n9i | PCG | Catabolite expression activator | / | 0.441 | |
| 4tuv | CPZ | Cytochrome P450 119 | 1.14 | 0.441 | |
| 4xdm | GDM | Heat shock cognate 90 kDa protein | / | 0.441 | |
| 5a4k | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.441 | |
| 1b8s | FAD | Cholesterol oxidase | 1.1.3.6 | 0.440 | |
| 1dg8 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 1ib0 | NAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.440 | |
| 1tll | NAP | Nitric oxide synthase, brain | 1.14.13.39 | 0.440 | |
| 1trg | CB3 | Thymidylate synthase | / | 0.440 | |
| 2ob0 | ACO | N-alpha-acetyltransferase 50 | / | 0.440 | |
| 3n7u | NAD | Formate dehydrogenase, chloroplastic/mitochondrial | / | 0.440 | |
| 3oy4 | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.440 | |
| 4ji9 | 1M3 | Tyrosine-protein kinase JAK2 | / | 0.440 | |
| 4kuh | CAA | 3-hydroxybutyryl-CoA dehydrogenase | / | 0.440 | |
| 4pl8 | ATP | Actin, alpha skeletal muscle | / | 0.440 | |
| 5d3q | GDP | Dynamin-1 | 3.6.5.5 | 0.440 |