sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2a2x | NA9 | Prothrombin | 3.4.21.5 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 2a2x | NA9 | Prothrombin | 3.4.21.5 | 1.000 | |
| 1ypl | RA8 | Prothrombin | 3.4.21.5 | 0.697 | |
| 1ypg | UIR | Prothrombin | 3.4.21.5 | 0.674 | |
| 1nm6 | L86 | Prothrombin | 3.4.21.5 | 0.661 | |
| 1z71 | L17 | Prothrombin | 3.4.21.5 | 0.650 | |
| 1xm1 | GAH | Prothrombin | 3.4.21.5 | 0.643 | |
| 1gj4 | 132 | Prothrombin | 3.4.21.5 | 0.636 | |
| 1d6w | 00R | Prothrombin | 3.4.21.5 | 0.633 | |
| 3c1k | T15 | Prothrombin | 3.4.21.5 | 0.632 | |
| 1ta6 | 177 | Prothrombin | 3.4.21.5 | 0.628 | |
| 1d3p | BT3 | Prothrombin | 3.4.21.5 | 0.625 | |
| 1t4v | 14A | Prothrombin | 3.4.21.5 | 0.623 | |
| 1d3d | BZT | Prothrombin | 3.4.21.5 | 0.622 | |
| 1ypm | RA4 | Prothrombin | 3.4.21.5 | 0.622 | |
| 2cn0 | F25 | Prothrombin | 3.4.21.5 | 0.622 | |
| 2cf9 | 348 | Prothrombin | 3.4.21.5 | 0.614 | |
| 2zfq | 45U | Prothrombin | 3.4.21.5 | 0.614 | |
| 3qwc | 98P | Prothrombin | 3.4.21.5 | 0.609 | |
| 1sb1 | 165 | Prothrombin | 3.4.21.5 | 0.607 | |
| 2zi2 | 24U | Prothrombin | 3.4.21.5 | 0.607 | |
| 2uuk | 897 | Prothrombin | 3.4.21.5 | 0.605 | |
| 4ayy | 9MX | Prothrombin | 3.4.21.5 | 0.605 | |
| 2ziq | 26U | Prothrombin | 3.4.21.5 | 0.602 | |
| 1mu8 | CDB | Prothrombin | 3.4.21.5 | 0.601 | |
| 2cf8 | ESH | Prothrombin | 3.4.21.5 | 0.598 | |
| 2zc9 | 22U | Prothrombin | 3.4.21.5 | 0.594 | |
| 2gde | SN3 | Prothrombin | 3.4.21.5 | 0.593 | |
| 3dhk | 23U | Prothrombin | 3.4.21.5 | 0.592 | |
| 1d4p | BPP | Prothrombin | 3.4.21.5 | 0.590 | |
| 2jh5 | 895 | Prothrombin | 3.4.21.5 | 0.589 | |
| 1zgi | 382 | Prothrombin | 3.4.21.5 | 0.588 | |
| 4ax9 | N5N | Prothrombin | 3.4.21.5 | 0.588 | |
| 1c4v | IH2 | Prothrombin | 3.4.21.5 | 0.587 | |
| 1bcu | PRL | Prothrombin | 3.4.21.5 | 0.586 | |
| 4lxb | 7R9 | Prothrombin | 3.4.21.5 | 0.585 | |
| 2anm | CDO | Prothrombin | 3.4.21.5 | 0.583 | |
| 3egk | M18 | Prothrombin | 3.4.21.5 | 0.581 | |
| 1ypj | UIB | Prothrombin | 3.4.21.5 | 0.580 | |
| 1mu6 | CDA | Prothrombin | 3.4.21.5 | 0.579 | |
| 2bvs | 2CE | Prothrombin | 3.4.21.5 | 0.579 | |
| 1ype | UIP | Prothrombin | 3.4.21.5 | 0.578 | |
| 1t4u | 81A | Prothrombin | 3.4.21.5 | 0.577 | |
| 1k22 | MEL | Prothrombin | 3.4.21.5 | 0.572 | |
| 2zhq | 27U | Prothrombin | 3.4.21.5 | 0.572 | |
| 1o0d | 163 | Prothrombin | 3.4.21.5 | 0.571 | |
| 2zhe | 13U | Prothrombin | 3.4.21.5 | 0.571 | |
| 2bdy | UNB | Prothrombin | 3.4.21.5 | 0.569 | |
| 1gj5 | 130 | Prothrombin | 3.4.21.5 | 0.568 | |
| 1ypk | CCR | Prothrombin | 3.4.21.5 | 0.568 | |
| 1mue | CDD | Prothrombin | 3.4.21.5 | 0.566 | |
| 4hfp | 15U | Prothrombin | 3.4.21.5 | 0.564 | |
| 2jh0 | 701 | Prothrombin | 3.4.21.5 | 0.563 | |
| 1kts | C24 | Prothrombin | 3.4.21.5 | 0.562 | |
| 1d9i | 00P | Prothrombin | 3.4.21.5 | 0.561 | |
| 2zda | 32U | Prothrombin | 3.4.21.5 | 0.561 | |
| 2znk | 31U | Prothrombin | 3.4.21.5 | 0.557 | |
| 1ghv | 120 | Prothrombin | 3.4.21.5 | 0.556 | |
| 1o2g | 696 | Prothrombin | 3.4.21.5 | 0.556 | |
| 2r2m | I50 | Prothrombin | 3.4.21.5 | 0.556 | |
| 1zgv | 501 | Prothrombin | 3.4.21.5 | 0.555 | |
| 4n3l | 2FN | Prothrombin | 3.4.21.5 | 0.555 | |
| 2zhf | 49U | Prothrombin | 3.4.21.5 | 0.554 | |
| 4ayv | 9MQ | Prothrombin | 3.4.21.5 | 0.554 | |
| 2jh6 | 894 | Prothrombin | 3.4.21.5 | 0.551 | |
| 3biv | 11U | Prothrombin | 3.4.21.5 | 0.551 | |
| 1o5g | CR9 | Prothrombin | 3.4.21.5 | 0.550 | |
| 1nzq | 162 | Prothrombin | 3.4.21.5 | 0.548 | |
| 1zrb | 062 | Prothrombin | 3.4.21.5 | 0.546 | |
| 2v3h | I25 | Prothrombin | 3.4.21.5 | 0.544 | |
| 2zdv | 37U | Prothrombin | 3.4.21.5 | 0.540 | |
| 1ta2 | 176 | Prothrombin | 3.4.21.5 | 0.538 | |
| 2zfr | 46U | Prothrombin | 3.4.21.5 | 0.538 | |
| 1uvs | I11 | Prothrombin | 3.4.21.5 | 0.535 | |
| 2zhw | 12U | Prothrombin | 3.4.21.5 | 0.534 | |
| 1ae8 | AZL | Prothrombin | 3.4.21.5 | 0.532 | |
| 1c4u | IH1 | Prothrombin | 3.4.21.5 | 0.532 | |
| 1a4w | QWE | Prothrombin | 3.4.21.5 | 0.528 | |
| 1c4y | IH3 | Prothrombin | 3.4.21.5 | 0.528 | |
| 1afe | ALZ | Prothrombin | 3.4.21.5 | 0.526 | |
| 2zgx | 29U | Prothrombin | 3.4.21.5 | 0.525 | |
| 3hat | GLY_VAL_ARG_RNG | Prothrombin | 3.4.21.5 | 0.525 | |
| 4rn6 | 15U | Prothrombin | 3.4.21.5 | 0.522 | |
| 1k21 | IGN | Prothrombin | 3.4.21.5 | 0.521 | |
| 1c5n | ESI | Prothrombin | 3.4.21.5 | 0.520 | |
| 1riw | OSC | Prothrombin | 3.4.21.5 | 0.520 | |
| 2v3o | I26 | Prothrombin | 3.4.21.5 | 0.513 | |
| 3biu | 10U | Prothrombin | 3.4.21.5 | 0.512 | |
| 3qdz | PRO_ALA_PRO_ARG | Prothrombin | 3.4.21.5 | 0.511 | |
| 4e7r | 0NW | Prothrombin | 3.4.21.5 | 0.511 | |
| 4az2 | 9MU | Prothrombin | 3.4.21.5 | 0.510 | |
| 4loy | 6XS | Prothrombin | 3.4.21.5 | 0.510 | |
| 1ny2 | ARG_PRO_PRO_GLY | Prothrombin | 3.4.21.5 | 0.509 | |
| 2zff | 53U | Prothrombin | 3.4.21.5 | 0.508 | |
| 3f68 | 91U | Prothrombin | 3.4.21.5 | 0.504 | |
| 4g95 | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.504 | |
| 2zf0 | 51U | Prothrombin | 3.4.21.5 | 0.501 | |
| 2zg0 | 50U | Prothrombin | 3.4.21.5 | 0.501 | |
| 3eq0 | 2TS | Prothrombin | 3.4.21.5 | 0.498 | |
| 2pks | G44 | Prothrombin | 3.4.21.5 | 0.497 | |
| 3s8p | SAM | Histone-lysine N-methyltransferase KMT5B | 2.1.1.43 | 0.493 | |
| 1zsk | 421 | Coagulation factor XI | 3.4.21.27 | 0.492 | |
| 3dux | 64U | Prothrombin | 3.4.21.5 | 0.489 | |
| 3uzw | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.488 | |
| 2zfp | 19U | Prothrombin | 3.4.21.5 | 0.487 | |
| 3cty | FAD | Probable thioredoxin reductase | / | 0.487 | |
| 1iqg | XME | Coagulation factor X | 3.4.21.6 | 0.484 | |
| 3kjs | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.482 | |
| 2qim | ZEA | Class 10 plant pathogenesis-related protein | / | 0.480 | |
| 2uuj | 896 | Prothrombin | 3.4.21.5 | 0.480 | |
| 3p17 | 99P | Prothrombin | 3.4.21.5 | 0.480 | |
| 3v2u | ATP | Protein GAL3 | / | 0.480 | |
| 3qto | 10P | Prothrombin | 3.4.21.5 | 0.479 | |
| 3v0x | ANH | Cationic trypsin | 3.4.21.4 | 0.477 | |
| 2zgb | 21U | Prothrombin | 3.4.21.5 | 0.476 | |
| 3oqf | S51 | Renin | 3.4.23.15 | 0.476 | |
| 1jwt | BLI | Prothrombin | 3.4.21.5 | 0.474 | |
| 1gky | 5GP | Guanylate kinase | 2.7.4.8 | 0.473 | |
| 1vzq | SHY | Prothrombin | 3.4.21.5 | 0.473 | |
| 3ada | NAD | Subunit alpha of sarocosine oxidase | / | 0.473 | |
| 4bup | SAM | Histone-lysine N-methyltransferase KMT5B | 2.1.1.43 | 0.473 | |
| 7kme | ACE_0BN_CHG_PRR | Prothrombin | 3.4.21.5 | 0.473 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.472 | |
| 1bil | 0IU | Renin | 3.4.23.15 | 0.471 | |
| 2g1o | 2IG | Renin | 3.4.23.15 | 0.470 | |
| 2w3b | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.470 | |
| 1ex7 | 5GP | Guanylate kinase | 2.7.4.8 | 0.469 | |
| 1w7g | MIU | Prothrombin | 3.4.21.5 | 0.469 | |
| 2cib | CM6 | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.469 | |
| 4gyz | D5M | Tyrosyl-DNA phosphodiesterase 2 | 3.1.4 | 0.469 | |
| 4jlk | 1NO | Deoxycytidine kinase | 2.7.1.74 | 0.469 | |
| 4gv4 | MEJ | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.468 | |
| 1dr3 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.467 | |
| 2g1n | 1IG | Renin | 3.4.23.15 | 0.467 | |
| 3oqk | S52 | Renin | 3.4.23.15 | 0.467 | |
| 3phi | NDP | Shikimate dehydrogenase (NADP(+)) | / | 0.467 | |
| 3qtv | 06P | Prothrombin | 3.4.21.5 | 0.467 | |
| 4bak | M67 | Prothrombin | 3.4.21.5 | 0.467 | |
| 4bao | MVF | Prothrombin | 3.4.21.5 | 0.467 | |
| 1rne | C60 | Renin | 3.4.23.15 | 0.466 | |
| 4btu | 6XS | Coagulation factor X | 3.4.21.6 | 0.466 | |
| 1vja | 7IN | Urokinase-type plasminogen activator | 3.4.21.73 | 0.465 | |
| 1sqt | UI3 | Urokinase-type plasminogen activator | 3.4.21.73 | 0.464 | |
| 1sl3 | 170 | Prothrombin | 3.4.21.5 | 0.463 | |
| 2qf2 | GDP | Phosphoenolpyruvate carboxykinase, cytosolic [GTP] | 4.1.1.32 | 0.463 | |
| 3oaf | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.463 | |
| 4kq6 | DLZ | 6,7-dimethyl-8-ribityllumazine synthase | / | 0.463 | |
| 4xgu | ADP | Putative pachytene checkpoint protein 2 | / | 0.463 | |
| 5cmx | 0G6 | Prothrombin | 3.4.21.5 | 0.463 | |
| 1drh | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.461 | |
| 1xvt | COA | L-carnitine CoA-transferase | / | 0.461 | |
| 1kbo | 340 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.460 | |
| 1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.460 | |
| 1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.460 | |
| 3qt6 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.460 | |
| 2hk9 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.459 | |
| 1u1g | BBB | Uridine phosphorylase | 2.4.2.3 | 0.458 | |
| 1nup | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.457 | |
| 2dhf | DZF | Dihydrofolate reductase | 1.5.1.3 | 0.457 | |
| 2nr4 | FMN | Conserved protein | / | 0.457 | |
| 3a1c | ACP | Probable copper-exporting P-type ATPase A | 3.6.3.54 | 0.457 | |
| 3fr5 | I4A | Fatty acid-binding protein, adipocyte | / | 0.457 | |
| 3nmp | PYV | Abscisic acid receptor PYL2 | / | 0.457 | |
| 3own | 3OX | Renin | 3.4.23.15 | 0.457 | |
| 1b2l | NDC | Alcohol dehydrogenase | 1.1.1.1 | 0.456 | |
| 1bim | 0QB | Renin | 3.4.23.15 | 0.456 | |
| 1vf3 | GDN | Glutathione S-transferase 3 | 2.5.1.18 | 0.456 | |
| 3dga | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.456 | |
| 3k1w | BFX | Renin | 3.4.23.15 | 0.456 | |
| 4eso | NAP | Putative oxidoreductase | / | 0.456 | |
| 4fui | UI3 | Urokinase-type plasminogen activator | 3.4.21.73 | 0.456 | |
| 1nfy | RTR | Coagulation factor X | 3.4.21.6 | 0.454 | |
| 1owe | 675 | Urokinase-type plasminogen activator | 3.4.21.73 | 0.454 | |
| 2g1r | 3IG | Renin | 3.4.23.15 | 0.454 | |
| 2iko | 7IG | Renin | 3.4.23.15 | 0.454 | |
| 2iku | LIY | Renin | 3.4.23.15 | 0.454 | |
| 2vqz | MGT | Polymerase basic protein 2 | / | 0.454 | |
| 4jlm | 1NN | Deoxycytidine kinase | 2.7.1.74 | 0.454 | |
| 4mlp | 2CX | Cryptochrome-2 | / | 0.454 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.453 | |
| 3aos | JH2 | Hemolymph juvenile hormone binding protein | / | 0.453 | |
| 1fap | RAP | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.452 | |
| 1fap | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.452 | |
| 1rsz | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.452 | |
| 2yy2 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.452 | |
| 3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.452 | |
| 3vsw | R31 | Renin | 3.4.23.15 | 0.452 | |
| 1toi | HCI | Aspartate aminotransferase | 2.6.1.1 | 0.451 | |
| 2g1y | 5IG | Renin | 3.4.23.15 | 0.451 | |
| 2wd8 | VGF | Pteridine reductase | / | 0.451 | |
| 3c27 | DKK | Prothrombin | 3.4.21.5 | 0.451 | |
| 3h3s | H15 | Collagen type IV alpha-3-binding protein | / | 0.451 | |
| 1rt9 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.450 | |
| 3h3q | H13 | Collagen type IV alpha-3-binding protein | / | 0.450 | |
| 3hwx | TPP | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.450 | |
| 4l7h | 1W1 | Beta-secretase 1 | 3.4.23.46 | 0.450 | |
| 1qoq | IGP | Tryptophan synthase alpha chain | / | 0.449 | |
| 2g00 | 4QC | Coagulation factor X | 3.4.21.6 | 0.449 | |
| 2iml | FMN | Uncharacterized protein | / | 0.449 | |
| 2jt2 | C90 | UDP-3-O-acyl-N-acetylglucosamine deacetylase | / | 0.449 | |
| 2v13 | C40 | Renin | 3.4.23.15 | 0.449 | |
| 3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.449 | |
| 3zv7 | NHG | Acetylcholinesterase | 3.1.1.7 | 0.449 | |
| 1ma0 | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.448 | |
| 1nt1 | T76 | Prothrombin | 3.4.21.5 | 0.448 | |
| 2e8u | IPE | Geranylgeranyl pyrophosphate synthase | / | 0.448 | |
| 2g24 | 7IG | Renin | 3.4.23.15 | 0.448 | |
| 2ojt | UBA | Glutamate receptor ionotropic, kainate 1 | / | 0.448 | |
| 2qbu | SAH | Precorrin-2 methyltransferase | / | 0.448 | |
| 3oew | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.448 | |
| 4ead | 0NP | Thymidine phosphorylase | 2.4.2.4 | 0.448 | |
| 4mrm | 2BY | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.448 | |
| 4nwz | FAD | FAD-dependent pyridine nucleotide-disulfide oxidoreductase | / | 0.448 | |
| 1gzu | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 | 2.7.7.1 | 0.447 | |
| 2g21 | L1B | Renin | 3.4.23.15 | 0.447 | |
| 2v16 | C47 | Renin | 3.4.23.15 | 0.447 | |
| 2xuk | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.447 | |
| 3k3h | BYE | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.447 | |
| 4fub | 4UP | Urokinase-type plasminogen activator | 3.4.21.73 | 0.447 | |
| 1dr5 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 1iqe | XMB | Coagulation factor X | 3.4.21.6 | 0.446 | |
| 1lv8 | 9PP | Purine nucleoside phosphorylase | 2.4.2.1 | 0.446 | |
| 2h2q | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.446 | |
| 2il2 | LIX | Renin | 3.4.23.15 | 0.446 | |
| 2y5g | FJD | Coagulation factor X | 3.4.21.6 | 0.446 | |
| 3vsx | R32 | Renin | 3.4.23.15 | 0.446 | |
| 4g2j | 0WF | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.446 | |
| 4lxj | LAN | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.446 | |
| 2aba | STR | Pentaerythritol tetranitrate reductase | / | 0.445 | |
| 2aq8 | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.445 | |
| 2cnd | FAD | Nitrate reductase [NADH] | 1.7.1.1 | 0.445 | |
| 1cjk | FOK | Adenylate cyclase type 2 | / | 0.444 | |
| 1cjk | FOK | Adenylate cyclase type 5 | / | 0.444 | |
| 1h66 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.444 | |
| 2cek | N8T | Acetylcholinesterase | 3.1.1.7 | 0.444 | |
| 2e94 | 364 | Geranylgeranyl pyrophosphate synthase | / | 0.444 | |
| 2npi | ATP | mRNA cleavage and polyadenylation factor CLP1 | / | 0.444 | |
| 2viv | VG2 | Urokinase-type plasminogen activator | 3.4.21.73 | 0.444 | |
| 2x3j | ATP | AcsD | / | 0.444 | |
| 2xvv | 9DN | Serum albumin | / | 0.444 | |
| 3own | 3OW | Renin | 3.4.23.15 | 0.444 | |
| 4fuf | 8UP | Urokinase-type plasminogen activator | 3.4.21.73 | 0.444 | |
| 4ms1 | 381 | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.444 | |
| 1dr2 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 1gsf | EAA | Glutathione S-transferase A1 | 2.5.1.18 | 0.443 | |
| 1hb3 | SCV | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
| 1kr2 | TAD | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 | 2.7.7.1 | 0.443 | |
| 2g1s | 4IG | Renin | 3.4.23.15 | 0.443 | |
| 2geu | COK | Pantothenate kinase | 2.7.1.33 | 0.443 | |
| 3af1 | GDP | Pantothenate kinase | 2.7.1.33 | 0.443 | |
| 3d84 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 3djf | BC3 | Purine nucleoside phosphorylase | / | 0.443 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.443 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.443 | |
| 3jus | BCD | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.443 | |
| 3oad | LPO | Renin | 3.4.23.15 | 0.443 | |
| 4epl | JAI | Jasmonic acid-amido synthetase JAR1 | 6.3.2 | 0.443 | |
| 4jlj | 1NM | Deoxycytidine kinase | 2.7.1.74 | 0.443 | |
| 1lvu | 9PP | Purine nucleoside phosphorylase | 2.4.2.1 | 0.442 | |
| 2iod | MYC | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.442 | |
| 2viy | VG3 | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 2xvi | FAD | Putative flavin-containing monooxygenase | / | 0.442 | |
| 3g70 | A5T | Renin | 3.4.23.15 | 0.442 | |
| 3inv | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.442 | |
| 4gv2 | 5ME | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.442 | |
| 5a01 | 12V | O-glycosyltransferase | / | 0.442 | |
| 1bwl | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.441 | |
| 1ege | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.441 | |
| 1i7p | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.441 | |
| 1rx1 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 1ygj | RMC | Pyridoxal kinase | 2.7.1.35 | 0.441 | |
| 2i4q | UA4 | Renin | 3.4.23.15 | 0.441 | |
| 2xuh | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.441 | |
| 4brd | ANP | Ectonucleoside triphosphate diphosphohydrolase I | / | 0.441 | |
| 4e90 | 7RG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.441 | |
| 4f7i | NAD | 3-isopropylmalate dehydrogenase | 1.1.1.85 | 0.441 | |
| 4m6j | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 4zzi | 1NS | NAD-dependent protein deacetylase sirtuin-1 | 3.5.1 | 0.441 | |
| 5fmm | MGT | Polymerase basic protein 2 | / | 0.441 | |
| 1pd9 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 1sq5 | ADP | Pantothenate kinase | 2.7.1.33 | 0.440 | |
| 1uk1 | FRQ | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.440 | |
| 2ivn | ANP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.440 | |
| 2xug | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.440 | |
| 3hii | PNT | Amiloride-sensitive amine oxidase [copper-containing] | / | 0.440 | |
| 3zkp | ERB | Erythromycin C-12 hydroxylase | 1.14.13.154 | 0.440 | |
| 4gh6 | LUO | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.440 |