sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1qyv | NAP | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 1qyv | NAP | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 1.000 | |
| 3tox | NAP | Putative oxidoreductase | / | 0.592 | |
| 1gco | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.582 | |
| 4b79 | NAD | Probable short-chain dehydrogenase | / | 0.581 | |
| 3ai2 | NDP | NADPH-sorbose reductase | / | 0.571 | |
| 1cyd | NDP | Carbonyl reductase [NADPH] 2 | 1.1.1.184 | 0.570 | |
| 1gee | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.570 | |
| 1fdu | NAP | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.566 | |
| 1g6k | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.561 | |
| 1xg5 | NAP | Dehydrogenase/reductase SDR family member 11 | / | 0.560 | |
| 4dmm | NAP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.560 | |
| 1ae1 | NAP | Tropinone reductase 1 | / | 0.556 | |
| 4j7u | NAP | Sepiapterin reductase | 1.1.1.153 | 0.555 | |
| 1xkq | NDP | Uncharacterized protein | / | 0.554 | |
| 3w8e | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.550 | |
| 3bhi | NAP | Carbonyl reductase [NADPH] 1 | 1.1.1.184 | 0.548 | |
| 4j7x | NAP | Sepiapterin reductase | 1.1.1.153 | 0.548 | |
| 3gy0 | NAP | NAD(P)-dependent oxidoreductase | / | 0.547 | |
| 3iah | NAP | Putative oxoacyl-(Acyl carrier protein) reductase | / | 0.546 | |
| 1e3s | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.542 | |
| 1ipe | NDP | Tropinone reductase 2 | 1.1.1.236 | 0.542 | |
| 1pr9 | NAP | L-xylulose reductase | 1.1.1.10 | 0.542 | |
| 1h5q | NAP | NADP-dependent mannitol dehydrogenase | 1.1.1.138 | 0.540 | |
| 1rwb | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.540 | |
| 1sny | NAP | LD36273p | / | 0.540 | |
| 5idw | NAP | Short-chain dehydrogenase/reductase SDR | / | 0.539 | |
| 4bmv | NAP | Short-chain dehydrogenase | / | 0.538 | |
| 2ztm | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.536 | |
| 2d1y | NAD | Oxidoreductase, short-chain dehydrogenase/reductase family | / | 0.535 | |
| 4qec | NAP | ElxO | / | 0.535 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.533 | |
| 3ai3 | NDP | NADPH-sorbose reductase | / | 0.532 | |
| 4hwk | NAP | Sepiapterin reductase | 1.1.1.153 | 0.530 | |
| 1w4z | NAP | Putative ketoacyl reductase | 1.3.1 | 0.529 | |
| 1wnt | NAP | L-xylulose reductase | 1.1.1.10 | 0.529 | |
| 2jah | NDP | Clavaldehyde dehydrogenase | / | 0.528 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.528 | |
| 4fw8 | NAI | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.528 | |
| 5jyd | NAD | Short chain dehydrogenase | / | 0.528 | |
| 2q2v | NAD | Beta-D-hydroxybutyrate dehydrogenase | / | 0.527 | |
| 2ztv | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.527 | |
| 3f1k | NAP | Uncharacterized oxidoreductase YciK | 1 | 0.527 | |
| 3qrw | NDP | Putative ketoacyl reductase | 1.3.1 | 0.526 | |
| 1nff | NAD | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.525 | |
| 4nbt | NAD | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.525 | |
| 2q2q | NAD | Beta-D-hydroxybutyrate dehydrogenase | / | 0.524 | |
| 4fj1 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.523 | |
| 4nbu | NAI | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.523 | |
| 2q1w | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.521 | |
| 3d3w | NAP | L-xylulose reductase | 1.1.1.10 | 0.520 | |
| 3p19 | NDP | Putative blue fluorescent protein | / | 0.520 | |
| 1g0n | NDP | Tetrahydroxynaphthalene reductase | 1.1.1.252 | 0.519 | |
| 1n5d | NDP | Carbonyl reductase [NADPH] 1 | / | 0.519 | |
| 1edo | NAP | 3-oxoacyl-[acyl-carrier-protein] reductase 1, chloroplastic | 1.1.1.100 | 0.518 | |
| 4fj2 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.518 | |
| 4iqg | NAP | Short-chain dehydrogenase/reductase SDR | / | 0.518 | |
| 4eso | NAP | Putative oxidoreductase | / | 0.517 | |
| 4fj0 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.517 | |
| 1xse | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.516 | |
| 4dc1 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.515 | |
| 2dte | NAI | Glucose 1-dehydrogenase related protein | / | 0.514 | |
| 3w8f | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.514 | |
| 1nfr | NAD | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.513 | |
| 2zat | NAP | Dehydrogenase/reductase SDR family member 4 | 1.1.1.184 | 0.513 | |
| 1x7h | NDP | Putative ketoacyl reductase | 1.3.1 | 0.512 | |
| 3qwf | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.512 | |
| 5jsf | NAD | 17-beta-hydroxysteroid dehydrogenase 14 | 1.1.1 | 0.511 | |
| 1x7g | NAP | Putative ketoacyl reductase | 1.3.1 | 0.510 | |
| 3g49 | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.510 | |
| 4z3d | NDP | Carbonyl reductase [NADPH] 1 | 1.1.1.184 | 0.510 | |
| 2hrb | NAP | Carbonyl reductase [NADPH] 3 | 1.1.1.184 | 0.509 | |
| 3rku | NAP | NADP-dependent 3-hydroxy acid dehydrogenase | / | 0.509 | |
| 3l77 | NJP | Short-chain alcohol dehydrogenase | / | 0.508 | |
| 4pvd | NDP | NADPH-dependent methylglyoxal reductase GRE2 | / | 0.508 | |
| 3vdq | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.507 | |
| 5jla | NAD | Putative short-chain dehydrogenase/reductase | / | 0.507 | |
| 2ewm | NAD | (S)-1-Phenylethanol dehydrogenase | 1.1.1.311 | 0.506 | |
| 2ztl | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.506 | |
| 1oaa | NAP | Sepiapterin reductase | 1.1.1.153 | 0.505 | |
| 2b37 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.505 | |
| 3rj5 | NAD | Alcohol dehydrogenase | 1.1.1.1 | 0.505 | |
| 4i5e | NAP | Alclohol dehydrogenase/short-chain dehydrogenase | / | 0.504 | |
| 1rkx | NAD | CDP-D-glucose-4,6-dehydratase | / | 0.503 | |
| 3w8d | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.503 | |
| 4bms | NAP | Alclohol dehydrogenase/short-chain dehydrogenase | / | 0.503 | |
| 4fn4 | NAD | Short chain dehydrogenase | / | 0.503 | |
| 5js6 | NAD | 17-beta-hydroxysteroid dehydrogenase 14 | 1.1.1 | 0.502 | |
| 2wyv | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.500 | |
| 2yut | NAP | Putative short-chain oxidoreductase | / | 0.500 | |
| 4gh5 | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.500 | |
| 4nbw | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.499 | |
| 3geg | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.498 | |
| 1g1a | NAD | dTDP-glucose 4,6-dehydratase | / | 0.497 | |
| 3uxy | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.497 | |
| 1bxk | NAD | dTDP-glucose 4,6-dehydratase 2 | / | 0.496 | |
| 2wdz | NAD | Galactitol dehydrogenase | / | 0.496 | |
| 3wds | NAD | NADH-dependent quinuclidinone reductase | / | 0.495 | |
| 4wji | NAP | Putative cyclohexadienyl dehydrogenase and ADH prephenate dehydrogenase | / | 0.494 | |
| 1zem | NAD | Xylitol dehydrogenase | / | 0.492 | |
| 3rj9 | NAD | Alcohol dehydrogenase | 1.1.1.1 | 0.492 | |
| 4is3 | NAD | 3alpha-hydroxy bile acid-CoA-ester 3-dehydrogenase 2 | 1.17.98.1 | 0.491 | |
| 4qed | NAP | ElxO | / | 0.490 | |
| 4rf2 | NAP | NADPH dependent R-specific alcohol dehydrogenase | / | 0.489 | |
| 4yag | NAI | C alpha-dehydrogenase | / | 0.488 | |
| 1geg | NAD | Diacetyl reductase [(S)-acetoin forming] | 1.1.1.304 | 0.487 | |
| 2bfo | NDP | Pteridine reductase 1 | 1.5.1.33 | 0.487 | |
| 2jkv | NAP | 6-phosphogluconate dehydrogenase, decarboxylating | 1.1.1.44 | 0.487 | |
| 3ehe | NAD | UDP-glucose 4-epimerase (GalE-1) | / | 0.487 | |
| 2hsd | NAD | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.486 | |
| 3lu1 | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.486 | |
| 1vl8 | NAP | Oxidoreductase, short chain dehydrogenase/reductase family | / | 0.485 | |
| 3r3s | NAD | Putative oxidoreductase | / | 0.484 | |
| 1sby | NAD | Alcohol dehydrogenase | 1.1.1.1 | 0.483 | |
| 3o4r | NAP | Dehydrogenase/reductase SDR family member 4 | 1.1.1.184 | 0.483 | |
| 3ruc | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.483 | |
| 2ag5 | NAD | 3-hydroxybutyrate dehydrogenase type 2 | / | 0.481 | |
| 2rbe | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.480 | |
| 3a28 | NAD | L-2,3-butanediol dehydrogenase | 1.1.1.76 | 0.479 | |
| 3sju | NDP | Keto reductase | / | 0.479 | |
| 3qwb | NDP | Probable quinone oxidoreductase | 1.6.5.5 | 0.478 | |
| 1b15 | NAE | Alcohol dehydrogenase | 1.1.1.1 | 0.477 | |
| 3bmo | NAP | Pteridine reductase | / | 0.477 | |
| 4yai | NAI | C alpha-dehydrogenase | / | 0.477 | |
| 1b14 | NAD | Alcohol dehydrogenase | 1.1.1.1 | 0.476 | |
| 3ak4 | NAD | NADH-dependent quinuclidinone reductase | / | 0.476 | |
| 3tn7 | NJP | Short-chain alcohol dehydrogenase | / | 0.476 | |
| 4bv9 | NDP | Ketimine reductase mu-crystallin | 1.5.1.25 | 0.476 | |
| 4egb | NAD | dTDP-glucose 4,6-dehydratase | / | 0.476 | |
| 1e3w | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.475 | |
| 2bd0 | NAP | Sepiapterin reductase | / | 0.475 | |
| 3ndr | NAD | Pyridoxal 4-dehydrogenase | 1.1.1.107 | 0.475 | |
| 1t2a | NDP | GDP-mannose 4,6 dehydratase | 4.2.1.47 | 0.474 | |
| 2dkn | NAI | 3-alpha-hydroxysteroid dehydrogenase | / | 0.474 | |
| 2p5u | NAD | UDP-glucose 4-epimerase | / | 0.474 | |
| 1e6w | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.473 | |
| 3nug | NAD | Pyridoxal 4-dehydrogenase | 1.1.1.107 | 0.473 | |
| 5dp2 | NAP | CurF | / | 0.473 | |
| 1n7h | NDP | GDP-mannose 4,6 dehydratase 2 | 4.2.1.47 | 0.472 | |
| 5lc1 | NAD | L-threonine 3-dehydrogenase | / | 0.472 | |
| 3s55 | NAD | Putative short-chain dehydrogenase/reductase | / | 0.471 | |
| 1n7g | NDP | GDP-mannose 4,6 dehydratase 2 | 4.2.1.47 | 0.470 | |
| 2c0c | NAP | Prostaglandin reductase 3 | 1 | 0.470 | |
| 3tsc | NAD | Uncharacterized protein | / | 0.470 | |
| 1yqd | NAP | Sinapyl alcohol dehydrogenase | / | 0.469 | |
| 2hun | NAD | 336aa long hypothetical dTDP-glucose 4,6-dehydratase | / | 0.469 | |
| 1bdb | NAD | Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase | / | 0.468 | |
| 4o0l | NDP | NADPH-dependent 3-quinuclidinone reductase | / | 0.468 | |
| 1qor | NDP | Quinone oxidoreductase 1 | / | 0.467 | |
| 2wsb | NAD | Galactitol dehydrogenase | / | 0.467 | |
| 3ru7 | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.467 | |
| 3rue | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.467 | |
| 3sx2 | NAD | Uncharacterized protein | / | 0.467 | |
| 1hdo | NAP | Flavin reductase (NADPH) | / | 0.466 | |
| 1iy8 | NAD | Levodione reductase | / | 0.466 | |
| 4oxy | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.466 | |
| 3uce | NDP | Dehydrogenase | / | 0.465 | |
| 4zju | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.465 | |
| 3sxp | NAD | ADP-L-glycero-D-mannoheptose-6-epimerase | / | 0.464 | |
| 2ekp | NAD | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.463 | |
| 4imp | NDP | Polyketide synthase extender modules 3-4 | / | 0.463 | |
| 4bkq | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.462 | |
| 1b16 | NAQ | Alcohol dehydrogenase | 1.1.1.1 | 0.461 | |
| 2gdz | NAD | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | 1.1.1.141 | 0.461 | |
| 3doc | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.461 | |
| 3ruf | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.461 | |
| 1mg5 | NAI | Alcohol dehydrogenase | 1.1.1.1 | 0.460 | |
| 3a4v | NAD | NDP-sugar epimerase | / | 0.460 | |
| 3ru9 | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.460 | |
| 3te5 | NAI | 5'-AMP-activated protein kinase subunit gamma | / | 0.460 | |
| 3wie | DN4 | Glucose 1-dehydrogenase | / | 0.460 | |
| 4fc7 | NAP | Peroxisomal 2,4-dienoyl-CoA reductase | 1.3.1.34 | 0.460 | |
| 2ie0 | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.459 | |
| 2ydx | NAP | Methionine adenosyltransferase 2 subunit beta | / | 0.459 | |
| 3w6u | NAP | 6-phosphogluconate dehydrogenase, NAD-binding protein | / | 0.459 | |
| 3gqv | NAP | Enoyl reductase LovC | 1 | 0.458 | |
| 3zbr | NAP | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.457 | |
| 4b8w | NAP | GDP-L-fucose synthase | 1.1.1.271 | 0.457 | |
| 4cql | NAD | Estradiol 17-beta-dehydrogenase 8 | 1.1.1.62 | 0.457 | |
| 4gll | NAD | UDP-glucuronic acid decarboxylase 1 | 4.1.1.35 | 0.457 | |
| 2ojt | UBA | Glutamate receptor ionotropic, kainate 1 | / | 0.456 | |
| 3wid | NAP | Glucose 1-dehydrogenase | / | 0.456 | |
| 4cr8 | NAD | N-acylmannosamine 1-dehydrogenase | 1.1.1.233 | 0.456 | |
| 4e5y | NDP | GDP-L-fucose synthase | 1.1.1.271 | 0.455 | |
| 2v6g | NAP | 3-oxo-Delta(4,5)-steroid 5-beta-reductase | / | 0.454 | |
| 3haz | FAD | Bifunctional protein PutA | / | 0.454 | |
| 3pgx | NAD | Uncharacterized NAD-dependent oxidoreductase MAP_4146 | / | 0.454 | |
| 3rua | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.454 | |
| 5koi | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.454 | |
| 1gre | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.452 | |
| 1v35 | NAI | Enoyl-ACP reductase | / | 0.452 | |
| 4uwm | FMN | 3,6-diketocamphane 1,6 monooxygenase | 1.14.13 | 0.452 | |
| 1xe5 | 5FE | Plasmepsin-2 | 3.4.23.39 | 0.451 | |
| 2cmj | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.451 | |
| 2yy7 | NAD | L-threonine dehydrogenase | / | 0.451 | |
| 1nyt | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.450 | |
| 2c20 | NAD | UDP-glucose 4-epimerase | / | 0.449 | |
| 3ijr | NAD | Oxidoreductase, short chain dehydrogenase/reductase family | / | 0.449 | |
| 1teh | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.448 | |
| 3b20 | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.448 | |
| 3pw8 | ACO | 1,2-phenylacetyl-CoA epoxidase, subunit A | 1.14.13.149 | 0.448 | |
| 3qv1 | NAD | Glyceraldehyde-3-phosphate dehydrogenase GAPA1, chloroplastic | 1.2.1.13 | 0.448 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.448 | |
| 2cnt | COA | Ribosomal-protein-alanine acetyltransferase | / | 0.447 | |
| 2gn8 | NAP | UDP-N-acetylglucosamine 4,6-dehydratase (inverting) | 4.2.1.115 | 0.447 | |
| 2q4b | NAP | Uncharacterized protein At5g02240 | / | 0.447 | |
| 4twr | NAD | NAD binding site:NAD-dependent epimerase/dehydratase:UDP-glucose 4-epimerase | / | 0.447 | |
| 1nai | NAD | UDP-glucose 4-epimerase | 5.1.3.2 | 0.446 | |
| 2y0m | ACO | Histone acetyltransferase KAT8 | / | 0.446 | |
| 3aho | 3A2 | Oligopeptidase | / | 0.446 | |
| 3rud | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.446 | |
| 4rvu | NDP | Probable quinone reductase Qor (NADPH:quinone reductase) (Zeta-crystallin homolog protein) | / | 0.446 | |
| 1eq2 | NAP | ADP-L-glycero-D-manno-heptose-6-epimerase | / | 0.445 | |
| 3s5w | NAP | L-ornithine N(5)-monooxygenase | / | 0.445 | |
| 1kol | NAD | Glutathione-independent formaldehyde dehydrogenase | / | 0.444 | |
| 1wvg | APR | CDP-glucose 4,6-dehydratase | 4.2.1.45 | 0.444 | |
| 3nx4 | NAP | Putative oxidoreductase | / | 0.444 | |
| 3tjz | GNP | ADP-ribosylation factor 1 | / | 0.444 | |
| 4bc7 | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.444 | |
| 1gra | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.443 | |
| 3mpj | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.443 | |
| 3u4c | NDP | NADPH-dependent reductase BacG | / | 0.443 | |
| 4rvg | TYD | D-mycarose 3-C-methyltransferase | / | 0.443 | |
| 1o8c | NDP | Probable acrylyl-CoA reductase AcuI | 1.3.1.84 | 0.442 | |
| 1yqx | NAP | Sinapyl alcohol dehydrogenase | / | 0.442 | |
| 2v6o | FAD | Thioredoxin glutathione reductase | / | 0.442 | |
| 3hl0 | NAD | Maleylacetate reductase | / | 0.442 | |
| 3p8z | 36A | Genome polyprotein | 2.1.1.56 | 0.442 | |
| 3s5w | FAD | L-ornithine N(5)-monooxygenase | / | 0.442 | |
| 4bby | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.442 | |
| 4g7g | VFV | Lanosterol 14-alpha-demethylase | / | 0.442 | |
| 4jnk | ZHK | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.442 | |
| 4m55 | NAD | UDP-glucuronic acid decarboxylase 1 | 4.1.1.35 | 0.442 | |
| 5dbg | NAD | Iridoid synthase | 1.3.1.99 | 0.442 | |
| 4jbi | NDP | Alcohol dehydrogenase (Zinc) | / | 0.441 | |
| 1rne | C60 | Renin | 3.4.23.15 | 0.440 | |
| 2iku | LIY | Renin | 3.4.23.15 | 0.440 | |
| 4bca | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.440 | |
| 4frk | DWD | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 4h3i | 10V | Beta-secretase 1 | 3.4.23.46 | 0.440 |