sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Modes are compared using Grim.
For more information, please see the following publication:
Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1nfr | NAD | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Mode Similarity |
Align |
|---|---|---|---|---|---|
| 1nfr | NAD | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 1.214 | |
| 1nff | NAD | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 1.116 | |
| 3pgx | NAD | Uncharacterized NAD-dependent oxidoreductase MAP_4146 | / | 0.978 | |
| 3s55 | NAD | Putative short-chain dehydrogenase/reductase | / | 0.951 | |
| 3sx2 | NAD | Uncharacterized protein | / | 0.934 | |
| 5ig2 | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.923 | |
| 2d1y | NAD | Oxidoreductase, short-chain dehydrogenase/reductase family | / | 0.916 | |
| 1edo | NAP | 3-oxoacyl-[acyl-carrier-protein] reductase 1, chloroplastic | 1.1.1.100 | 0.903 | |
| 3a28 | NAD | L-2,3-butanediol dehydrogenase | 1.1.1.76 | 0.880 | |
| 5jsf | NAD | 17-beta-hydroxysteroid dehydrogenase 14 | 1.1.1 | 0.880 | |
| 5js6 | NAD | 17-beta-hydroxysteroid dehydrogenase 14 | 1.1.1 | 0.871 | |
| 3wds | NAD | NADH-dependent quinuclidinone reductase | / | 0.853 | |
| 4z3d | NDP | Carbonyl reductase [NADPH] 1 | 1.1.1.184 | 0.852 | |
| 3tsc | NAD | Uncharacterized protein | / | 0.848 | |
| 1vl8 | NAP | Oxidoreductase, short chain dehydrogenase/reductase family | / | 0.828 | |
| 1e3s | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.824 | |
| 3ruc | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.824 | |
| 4nbt | NAD | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.824 | |
| 1h5q | NAP | NADP-dependent mannitol dehydrogenase | 1.1.1.138 | 0.823 | |
| 3nug | NAD | Pyridoxal 4-dehydrogenase | 1.1.1.107 | 0.816 | |
| 4bmv | NAP | Short-chain dehydrogenase | / | 0.815 | |
| 4nbu | NAI | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.809 | |
| 4is3 | NAD | 3alpha-hydroxy bile acid-CoA-ester 3-dehydrogenase 2 | 1.17.98.1 | 0.808 | |
| 3gy0 | NAP | NAD(P)-dependent oxidoreductase | / | 0.806 | |
| 4dc0 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.802 | |
| 4wec | NAD | Short chain dehydrogenase | / | 0.800 | |
| 2bgm | NAJ | Secoisolariciresinol dehydrogenase | 1.1.1.331 | 0.797 | |
| 3rj9 | NAD | Alcohol dehydrogenase | 1.1.1.1 | 0.796 | |
| 3ndr | NAD | Pyridoxal 4-dehydrogenase | 1.1.1.107 | 0.795 | |
| 5idw | NAP | Short-chain dehydrogenase/reductase SDR | / | 0.795 | |
| 2wsb | NAD | Galactitol dehydrogenase | / | 0.793 | |
| 1xse | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.792 | |
| 2y99 | NAD | Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase | 1.3.1.56 | 0.791 | |
| 3rj5 | NAD | Alcohol dehydrogenase | 1.1.1.1 | 0.791 | |
| 1g0n | NDP | Tetrahydroxynaphthalene reductase | 1.1.1.252 | 0.790 | |
| 1geg | NAD | Diacetyl reductase [(S)-acetoin forming] | 1.1.1.304 | 0.790 | |
| 1xg5 | NAP | Dehydrogenase/reductase SDR family member 11 | / | 0.788 | |
| 3ak4 | NAD | NADH-dependent quinuclidinone reductase | / | 0.787 | |
| 3lu1 | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.787 | |
| 3ru7 | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.787 | |
| 3l77 | NJP | Short-chain alcohol dehydrogenase | / | 0.786 | |
| 4qec | NAP | ElxO | / | 0.786 | |
| 4gh5 | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.784 | |
| 1pr9 | NAP | L-xylulose reductase | 1.1.1.10 | 0.783 | |
| 1e3w | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.782 | |
| 3ruf | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.781 | |
| 3ruh | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.781 | |
| 3bhi | NAP | Carbonyl reductase [NADPH] 1 | 1.1.1.184 | 0.780 | |
| 4j7x | NAP | Sepiapterin reductase | 1.1.1.153 | 0.779 | |
| 1cyd | NDP | Carbonyl reductase [NADPH] 2 | 1.1.1.184 | 0.778 | |
| 3tn7 | NJP | Short-chain alcohol dehydrogenase | / | 0.778 | |
| 4fj2 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.778 | |
| 1e6w | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.777 | |
| 2dte | NAI | Glucose 1-dehydrogenase related protein | / | 0.777 | |
| 3w8e | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.777 | |
| 4b79 | NAD | Probable short-chain dehydrogenase | / | 0.777 | |
| 2wdz | NAD | Galactitol dehydrogenase | / | 0.776 | |
| 1n5d | NDP | Carbonyl reductase [NADPH] 1 | / | 0.775 | |
| 3ai3 | NDP | NADPH-sorbose reductase | / | 0.774 | |
| 3ru9 | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.774 | |
| 4j7u | NAP | Sepiapterin reductase | 1.1.1.153 | 0.773 | |
| 3iah | NAP | Putative oxoacyl-(Acyl carrier protein) reductase | / | 0.772 | |
| 2o23 | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.771 | |
| 4k6f | NAP | Putative Acetoacetyl-CoA reductase | / | 0.771 | |
| 3rua | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.770 | |
| 4fj0 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.770 | |
| 1orr | NAD | CDP-paratose 2-epimerase | / | 0.769 | |
| 4dc1 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.768 | |
| 2c54 | NAD | GDP-mannose 3,5-epimerase | 5.1.3.18 | 0.767 | |
| 3o26 | NDP | Salutaridine reductase | / | 0.767 | |
| 1zem | NAD | Xylitol dehydrogenase | / | 0.766 | |
| 2ztv | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.764 | |
| 1kvr | NAD | UDP-glucose 4-epimerase | 5.1.3.2 | 0.762 | |
| 1oaa | NAP | Sepiapterin reductase | 1.1.1.153 | 0.762 | |
| 3ijr | NAD | Oxidoreductase, short chain dehydrogenase/reductase family | / | 0.762 | |
| 5jla | NAD | Putative short-chain dehydrogenase/reductase | / | 0.762 | |
| 1w4z | NAP | Putative ketoacyl reductase | 1.3.1 | 0.761 | |
| 4yai | NAI | C alpha-dehydrogenase | / | 0.761 | |
| 3g49 | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.759 | |
| 3w8d | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.758 | |
| 2q1t | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.756 | |
| 3qwf | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.755 | |
| 4fn4 | NAD | Short chain dehydrogenase | / | 0.755 | |
| 1mg5 | NAI | Alcohol dehydrogenase | 1.1.1.1 | 0.754 | |
| 4fj1 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.754 | |
| 2c59 | NAD | GDP-mannose 3,5-epimerase | 5.1.3.18 | 0.752 | |
| 3rku | NAP | NADP-dependent 3-hydroxy acid dehydrogenase | / | 0.752 | |
| 1gee | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.751 | |
| 1x7h | NDP | Putative ketoacyl reductase | 1.3.1 | 0.751 | |
| 1gco | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.750 | |
| 4pvd | NDP | NADPH-dependent methylglyoxal reductase GRE2 | / | 0.750 | |
| 3qrw | NDP | Putative ketoacyl reductase | 1.3.1 | 0.749 | |
| 4qed | NAP | ElxO | / | 0.749 | |
| 3p19 | NDP | Putative blue fluorescent protein | / | 0.747 | |
| 3vdq | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.747 | |
| 4hwk | NAP | Sepiapterin reductase | 1.1.1.153 | 0.747 | |
| 4iqg | NAP | Short-chain dehydrogenase/reductase SDR | / | 0.747 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.746 | |
| 2rbe | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.745 | |
| 3ai2 | NDP | NADPH-sorbose reductase | / | 0.745 | |
| 2bd0 | NAP | Sepiapterin reductase | / | 0.744 | |
| 5b1y | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.744 | |
| 1ipe | NDP | Tropinone reductase 2 | 1.1.1.236 | 0.741 | |
| 2ydx | NAP | Methionine adenosyltransferase 2 subunit beta | / | 0.741 | |
| 3icp | NAD | NAD-dependent epimerase/dehydratase | / | 0.740 | |
| 4kwh | NAP | Reductase homolog | / | 0.740 | |
| 1b2l | NDC | Alcohol dehydrogenase | 1.1.1.1 | 0.739 | |
| 3d3w | NAP | L-xylulose reductase | 1.1.1.10 | 0.738 | |
| 1sny | NAP | LD36273p | / | 0.737 | |
| 1u7t | TDT | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.737 | |
| 2ag5 | NAD | 3-hydroxybutyrate dehydrogenase type 2 | / | 0.737 | |
| 4rf2 | NAP | NADPH dependent R-specific alcohol dehydrogenase | / | 0.737 | |
| 2hsd | NAD | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.735 | |
| 2pzj | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.735 | |
| 1x7g | NAP | Putative ketoacyl reductase | 1.3.1 | 0.734 | |
| 2c29 | NAP | Dihydroflavonol 4-reductase | / | 0.733 | |
| 1bdb | NAD | Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase | / | 0.732 | |
| 2q2q | NAD | Beta-D-hydroxybutyrate dehydrogenase | / | 0.732 | |
| 1rwb | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.731 | |
| 4twr | NAD | NAD binding site:NAD-dependent epimerase/dehydratase:UDP-glucose 4-epimerase | / | 0.731 | |
| 4m87 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.730 | |
| 3sxp | NAD | ADP-L-glycero-D-mannoheptose-6-epimerase | / | 0.729 | |
| 3ko8 | NAD | NAD-dependent epimerase/dehydratase | / | 0.728 | |
| 3orf | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.728 | |
| 3o4r | NAP | Dehydrogenase/reductase SDR family member 4 | 1.1.1.184 | 0.727 | |
| 1b15 | NAE | Alcohol dehydrogenase | 1.1.1.1 | 0.726 | |
| 2hrb | NAP | Carbonyl reductase [NADPH] 3 | 1.1.1.184 | 0.726 | |
| 4i5e | NAP | Alclohol dehydrogenase/short-chain dehydrogenase | / | 0.726 | |
| 1sby | NAD | Alcohol dehydrogenase | 1.1.1.1 | 0.724 | |
| 3a9w | NAD | NDP-sugar epimerase | / | 0.724 | |
| 1xkq | NDP | Uncharacterized protein | / | 0.723 | |
| 2ztl | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.723 | |
| 2h9i | EAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.722 | |
| 3sju | NDP | Keto reductase | / | 0.722 | |
| 4lis | NAD | UDP-glucose 4-epimerase (Eurofung) | / | 0.721 | |
| 2b4q | NAP | Rhamnolipids biosynthesis 3-oxoacyl-[acyl-carrier-protein] reductase | 1.1.1.100 | 0.720 | |
| 2yy7 | NAD | L-threonine dehydrogenase | / | 0.720 | |
| 1fdu | NAP | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.719 | |
| 2ztm | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.719 | |
| 2q1w | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.718 | |
| 3a1n | NAD | NDP-sugar epimerase | / | 0.718 | |
| 4fw8 | NAI | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.718 | |
| 1nah | NAD | UDP-glucose 4-epimerase | 5.1.3.2 | 0.717 | |
| 3of2 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.715 | |
| 3uic | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.714 | |
| 2dkn | NAI | 3-alpha-hydroxysteroid dehydrogenase | / | 0.713 | |
| 4cql | NAD | Estradiol 17-beta-dehydrogenase 8 | 1.1.1.62 | 0.711 | |
| 4yag | NAI | C alpha-dehydrogenase | / | 0.710 | |
| 1i3l | NAD | UDP-glucose 4-epimerase | / | 0.709 | |
| 1qyv | NAP | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.706 | |
| 2q2v | NAD | Beta-D-hydroxybutyrate dehydrogenase | / | 0.706 | |
| 2ztu | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.706 | |
| 3oew | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.706 | |
| 2wyv | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.705 | |
| 1ek5 | NAD | UDP-glucose 4-epimerase | / | 0.704 | |
| 2yut | NAP | Putative short-chain oxidoreductase | / | 0.704 | |
| 5jyd | NAD | Short chain dehydrogenase | / | 0.704 | |
| 2ekp | NAD | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.703 | |
| 4hp8 | NAP | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.703 | |
| 2nv6 | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.702 | |
| 4zju | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.702 | |
| 4u7w | NDP | MxaA | / | 0.701 | |
| 2b69 | NAD | UDP-glucuronic acid decarboxylase 1 | 4.1.1.35 | 0.700 | |
| 3ajr | NAD | NDP-sugar epimerase | / | 0.700 | |
| 4ej0 | NAP | ADP-L-glycero-D-manno-heptose-6-epimerase | / | 0.699 | |
| 2jah | NDP | Clavaldehyde dehydrogenase | / | 0.698 | |
| 3rud | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.698 | |
| 2b37 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.697 | |
| 4bqp | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.697 | |
| 5cpb | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.697 | |
| 1b14 | NAD | Alcohol dehydrogenase | 1.1.1.1 | 0.696 | |
| 3ehe | NAD | UDP-glucose 4-epimerase (GalE-1) | / | 0.696 | |
| 4dmm | NAP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.696 | |
| 1u7t | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.695 | |
| 4egb | NAD | dTDP-glucose 4,6-dehydratase | / | 0.694 | |
| 3w8f | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.692 | |
| 4b8z | NAP | GDP-L-fucose synthase | 1.1.1.271 | 0.692 | |
| 1nai | NAD | UDP-glucose 4-epimerase | 5.1.3.2 | 0.691 | |
| 1ae1 | NAP | Tropinone reductase 1 | / | 0.690 | |
| 3aw9 | NAD | NAD-dependent epimerase/dehydratase | / | 0.690 | |
| 3oey | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.689 | |
| 3r3s | NAD | Putative oxidoreductase | / | 0.689 | |
| 4nbw | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.689 | |
| 4bii | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.687 | |
| 2ewm | NAD | (S)-1-Phenylethanol dehydrogenase | 1.1.1.311 | 0.686 | |
| 2c20 | NAD | UDP-glucose 4-epimerase | / | 0.684 | |
| 3geg | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.684 | |
| 2b35 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.683 | |
| 4bms | NAP | Alclohol dehydrogenase/short-chain dehydrogenase | / | 0.682 | |
| 1g6k | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.679 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.679 | |
| 4gll | NAD | UDP-glucuronic acid decarboxylase 1 | 4.1.1.35 | 0.679 | |
| 1p44 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.677 | |
| 1eny | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.676 | |
| 3sj7 | NDP | 3-oxoacyl-(Acyl-carrier-protein) reductase, putative | / | 0.676 | |
| 2ggs | NDP | dTDP-4-dehydrorhamnose reductase | / | 0.674 | |
| 4trn | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.674 | |
| 5d2e | NAP | MlnE | / | 0.674 | |
| 2ieb | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.673 | |
| 3o03 | NAP | Dehydrogenase with different specificities (Related to short-chain alcohol dehydrogenase) | / | 0.673 | |
| 4dre | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.673 | |
| 4bgi | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.672 | |
| 3wmx | NAD | NAD dependent epimerase/dehydratase | / | 0.671 | |
| 4dqu | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.671 | |
| 4dti | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.671 | |
| 2p5u | NAD | UDP-glucose 4-epimerase | / | 0.669 | |
| 3aut | NAI | Glucose 1-dehydrogenase 4 | 1.1.1.47 | 0.667 | |
| 2idz | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.666 | |
| 2p5y | NAD | UDP-glucose 4-epimerase | / | 0.666 | |
| 2aqi | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.663 | |
| 1w8d | NAP | 2,4-dienoyl-CoA reductase, mitochondrial | 1.3.1.34 | 0.662 | |
| 5koi | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.661 | |
| 2i9p | NAD | 3-hydroxyisobutyrate dehydrogenase, mitochondrial | 1.1.1.31 | 0.660 | |
| 2ntv | P1H | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.660 | |
| 4b4o | NDP | Epimerase family protein SDR39U1 | / | 0.660 | |
| 4wji | NAP | Putative cyclohexadienyl dehydrogenase and ADH prephenate dehydrogenase | / | 0.660 | |
| 3oa2 | NAD | UDP-N-acetyl-2-amino-2-deoxy-D-glucuronate oxidase | / | 0.658 | |
| 4yr9 | NAD | L-threonine 3-dehydrogenase, mitochondrial | 1.1.1.103 | 0.657 | |
| 3uxy | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.656 | |
| 1fk8 | NAD | 3-alpha-hydroxysteroid dehydrogenase/carbonyl reductase | 1.1.1.50 | 0.655 | |
| 1iy8 | NAD | Levodione reductase | / | 0.655 | |
| 4qxm | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.655 | |
| 2z95 | NDP | GDP-mannose 4,6-dehydratase | / | 0.654 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.654 | |
| 4nd2 | A3D | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.654 | |
| 1npt | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.651 | |
| 1u7h | NAD | Putative ornithine cyclodeaminase | / | 0.651 | |
| 3mvq | NDP | Glutamate dehydrogenase 1, mitochondrial | 1.4.1.3 | 0.651 | |
| 3w6u | NAP | 6-phosphogluconate dehydrogenase, NAD-binding protein | / | 0.651 | |
| 5fa5 | MTA | Protein arginine N-methyltransferase 5 | / | 0.651 | |
| 1pzh | NAD | Lactate dehydrogenase | / | 0.650 | |
| 2aq8 | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.650 | |
| 5lc1 | NAD | L-threonine 3-dehydrogenase | / | 0.650 |