sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Modes are compared using Grim.
For more information, please see the following publication:
Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1nff | NAD | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Mode Similarity |
Align |
|---|---|---|---|---|---|
| 1nff | NAD | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 1.252 | |
| 1nfr | NAD | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 1.116 | |
| 3sx2 | NAD | Uncharacterized protein | / | 1.058 | |
| 3pgx | NAD | Uncharacterized NAD-dependent oxidoreductase MAP_4146 | / | 1.050 | |
| 3s55 | NAD | Putative short-chain dehydrogenase/reductase | / | 1.026 | |
| 3tsc | NAD | Uncharacterized protein | / | 0.961 | |
| 5ig2 | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.931 | |
| 2gdz | NAD | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | 1.1.1.141 | 0.907 | |
| 2d1y | NAD | Oxidoreductase, short-chain dehydrogenase/reductase family | / | 0.901 | |
| 5js6 | NAD | 17-beta-hydroxysteroid dehydrogenase 14 | 1.1.1 | 0.873 | |
| 1e3w | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.869 | |
| 5jsf | NAD | 17-beta-hydroxysteroid dehydrogenase 14 | 1.1.1 | 0.865 | |
| 3a28 | NAD | L-2,3-butanediol dehydrogenase | 1.1.1.76 | 0.859 | |
| 1e3s | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.853 | |
| 4nbu | NAI | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.848 | |
| 1edo | NAP | 3-oxoacyl-[acyl-carrier-protein] reductase 1, chloroplastic | 1.1.1.100 | 0.847 | |
| 1geg | NAD | Diacetyl reductase [(S)-acetoin forming] | 1.1.1.304 | 0.841 | |
| 1iy8 | NAD | Levodione reductase | / | 0.841 | |
| 2wsb | NAD | Galactitol dehydrogenase | / | 0.839 | |
| 1e6w | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.836 | |
| 2o23 | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.830 | |
| 4nbt | NAD | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.828 | |
| 3wds | NAD | NADH-dependent quinuclidinone reductase | / | 0.827 | |
| 2q1w | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.817 | |
| 4dc0 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.817 | |
| 1orr | NAD | CDP-paratose 2-epimerase | / | 0.815 | |
| 4gh5 | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.814 | |
| 1vl8 | NAP | Oxidoreductase, short chain dehydrogenase/reductase family | / | 0.812 | |
| 3p19 | NDP | Putative blue fluorescent protein | / | 0.810 | |
| 3l77 | NJP | Short-chain alcohol dehydrogenase | / | 0.809 | |
| 1kvr | NAD | UDP-glucose 4-epimerase | 5.1.3.2 | 0.808 | |
| 1u7t | TDT | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.806 | |
| 2bgm | NAJ | Secoisolariciresinol dehydrogenase | 1.1.1.331 | 0.806 | |
| 2wdz | NAD | Galactitol dehydrogenase | / | 0.805 | |
| 3tn7 | NJP | Short-chain alcohol dehydrogenase | / | 0.803 | |
| 4is3 | NAD | 3alpha-hydroxy bile acid-CoA-ester 3-dehydrogenase 2 | 1.17.98.1 | 0.803 | |
| 3o26 | NDP | Salutaridine reductase | / | 0.802 | |
| 3ruf | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.802 | |
| 5idw | NAP | Short-chain dehydrogenase/reductase SDR | / | 0.798 | |
| 2jah | NDP | Clavaldehyde dehydrogenase | / | 0.797 | |
| 5jla | NAD | Putative short-chain dehydrogenase/reductase | / | 0.796 | |
| 1fdu | NAP | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.795 | |
| 3ruc | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.795 | |
| 4z3d | NDP | Carbonyl reductase [NADPH] 1 | 1.1.1.184 | 0.795 | |
| 2c59 | NAD | GDP-mannose 3,5-epimerase | 5.1.3.18 | 0.793 | |
| 3rku | NAP | NADP-dependent 3-hydroxy acid dehydrogenase | / | 0.793 | |
| 3sju | NDP | Keto reductase | / | 0.792 | |
| 1g0n | NDP | Tetrahydroxynaphthalene reductase | 1.1.1.252 | 0.789 | |
| 3ruh | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.789 | |
| 3bhi | NAP | Carbonyl reductase [NADPH] 1 | 1.1.1.184 | 0.786 | |
| 3rua | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.784 | |
| 4bmv | NAP | Short-chain dehydrogenase | / | 0.784 | |
| 3ru9 | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.783 | |
| 3rj9 | NAD | Alcohol dehydrogenase | 1.1.1.1 | 0.779 | |
| 4j7u | NAP | Sepiapterin reductase | 1.1.1.153 | 0.777 | |
| 4iqg | NAP | Short-chain dehydrogenase/reductase SDR | / | 0.776 | |
| 1x7h | NDP | Putative ketoacyl reductase | 1.3.1 | 0.775 | |
| 3qrw | NDP | Putative ketoacyl reductase | 1.3.1 | 0.774 | |
| 2q1s | NAI | Putative nucleotide sugar epimerase/ dehydratase | / | 0.773 | |
| 2bd0 | NAP | Sepiapterin reductase | / | 0.772 | |
| 3lu1 | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.771 | |
| 4yag | NAI | C alpha-dehydrogenase | / | 0.771 | |
| 3gy0 | NAP | NAD(P)-dependent oxidoreductase | / | 0.770 | |
| 1u7t | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.768 | |
| 1nah | NAD | UDP-glucose 4-epimerase | 5.1.3.2 | 0.767 | |
| 2nnl | NAP | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.767 | |
| 3rj5 | NAD | Alcohol dehydrogenase | 1.1.1.1 | 0.767 | |
| 3ru7 | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.767 | |
| 4hwk | NAP | Sepiapterin reductase | 1.1.1.153 | 0.766 | |
| 3ai3 | NDP | NADPH-sorbose reductase | / | 0.763 | |
| 3nug | NAD | Pyridoxal 4-dehydrogenase | 1.1.1.107 | 0.763 | |
| 4wec | NAD | Short chain dehydrogenase | / | 0.763 | |
| 2y99 | NAD | Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase | 1.3.1.56 | 0.762 | |
| 4u7w | NDP | MxaA | / | 0.762 | |
| 1xg5 | NAP | Dehydrogenase/reductase SDR family member 11 | / | 0.761 | |
| 2c54 | NAD | GDP-mannose 3,5-epimerase | 5.1.3.18 | 0.761 | |
| 2p5y | NAD | UDP-glucose 4-epimerase | / | 0.761 | |
| 1pr9 | NAP | L-xylulose reductase | 1.1.1.10 | 0.759 | |
| 1cyd | NDP | Carbonyl reductase [NADPH] 2 | 1.1.1.184 | 0.758 | |
| 1oaa | NAP | Sepiapterin reductase | 1.1.1.153 | 0.758 | |
| 4fn4 | NAD | Short chain dehydrogenase | / | 0.757 | |
| 3iah | NAP | Putative oxoacyl-(Acyl carrier protein) reductase | / | 0.756 | |
| 3icp | NAD | NAD-dependent epimerase/dehydratase | / | 0.756 | |
| 3sxp | NAD | ADP-L-glycero-D-mannoheptose-6-epimerase | / | 0.755 | |
| 1mg5 | NAI | Alcohol dehydrogenase | 1.1.1.1 | 0.754 | |
| 1zem | NAD | Xylitol dehydrogenase | / | 0.754 | |
| 3uce | NDP | Dehydrogenase | / | 0.754 | |
| 2dkn | NAI | 3-alpha-hydroxysteroid dehydrogenase | / | 0.753 | |
| 1i3l | NAD | UDP-glucose 4-epimerase | / | 0.752 | |
| 2ag5 | NAD | 3-hydroxybutyrate dehydrogenase type 2 | / | 0.752 | |
| 3qwf | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.751 | |
| 1x7g | NAP | Putative ketoacyl reductase | 1.3.1 | 0.750 | |
| 4j7x | NAP | Sepiapterin reductase | 1.1.1.153 | 0.750 | |
| 4kwh | NAP | Reductase homolog | / | 0.750 | |
| 2zat | NAP | Dehydrogenase/reductase SDR family member 4 | 1.1.1.184 | 0.747 | |
| 3o4r | NAP | Dehydrogenase/reductase SDR family member 4 | 1.1.1.184 | 0.747 | |
| 4qec | NAP | ElxO | / | 0.747 | |
| 3w8f | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.746 | |
| 5b1y | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.746 | |
| 2q2q | NAD | Beta-D-hydroxybutyrate dehydrogenase | / | 0.744 | |
| 2q1u | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.743 | |
| 4b79 | NAD | Probable short-chain dehydrogenase | / | 0.743 | |
| 1n5d | NDP | Carbonyl reductase [NADPH] 1 | / | 0.742 | |
| 1rwb | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.742 | |
| 3geg | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.742 | |
| 4fj0 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.740 | |
| 4lis | NAD | UDP-glucose 4-epimerase (Eurofung) | / | 0.739 | |
| 2pzj | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.738 | |
| 3w8e | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.738 | |
| 2c29 | NAP | Dihydroflavonol 4-reductase | / | 0.737 | |
| 2yut | NAP | Putative short-chain oxidoreductase | / | 0.736 | |
| 3a9w | NAD | NDP-sugar epimerase | / | 0.736 | |
| 1nai | NAD | UDP-glucose 4-epimerase | 5.1.3.2 | 0.735 | |
| 3ai2 | NDP | NADPH-sorbose reductase | / | 0.735 | |
| 3aw9 | NAD | NAD-dependent epimerase/dehydratase | / | 0.735 | |
| 3ko8 | NAD | NAD-dependent epimerase/dehydratase | / | 0.735 | |
| 4qed | NAP | ElxO | / | 0.734 | |
| 1sny | NAP | LD36273p | / | 0.730 | |
| 2hsd | NAD | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.729 | |
| 1w4z | NAP | Putative ketoacyl reductase | 1.3.1 | 0.727 | |
| 2rbe | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.726 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.726 | |
| 4dc1 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.726 | |
| 4i5e | NAP | Alclohol dehydrogenase/short-chain dehydrogenase | / | 0.726 | |
| 1gco | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.725 | |
| 1bdb | NAD | Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase | / | 0.724 | |
| 2c20 | NAD | UDP-glucose 4-epimerase | / | 0.724 | |
| 2q2v | NAD | Beta-D-hydroxybutyrate dehydrogenase | / | 0.724 | |
| 3a4v | NAD | NDP-sugar epimerase | / | 0.724 | |
| 1b16 | NAQ | Alcohol dehydrogenase | 1.1.1.1 | 0.722 | |
| 1gee | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.722 | |
| 2ggs | NDP | dTDP-4-dehydrorhamnose reductase | / | 0.721 | |
| 4fj1 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.721 | |
| 4yai | NAI | C alpha-dehydrogenase | / | 0.721 | |
| 1b15 | NAE | Alcohol dehydrogenase | 1.1.1.1 | 0.719 | |
| 1rkx | NAD | CDP-D-glucose-4,6-dehydratase | / | 0.719 | |
| 1ek5 | NAD | UDP-glucose 4-epimerase | / | 0.718 | |
| 2ydx | NAP | Methionine adenosyltransferase 2 subunit beta | / | 0.718 | |
| 1h5q | NAP | NADP-dependent mannitol dehydrogenase | 1.1.1.138 | 0.717 | |
| 3orf | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.717 | |
| 3w8d | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.717 | |
| 2ztv | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.715 | |
| 2hrb | NAP | Carbonyl reductase [NADPH] 3 | 1.1.1.184 | 0.714 | |
| 3ak4 | NAD | NADH-dependent quinuclidinone reductase | / | 0.714 | |
| 2b69 | NAD | UDP-glucuronic acid decarboxylase 1 | 4.1.1.35 | 0.713 | |
| 4egb | NAD | dTDP-glucose 4,6-dehydratase | / | 0.711 | |
| 3ajr | NAD | NDP-sugar epimerase | / | 0.710 | |
| 3g49 | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.709 | |
| 4cql | NAD | Estradiol 17-beta-dehydrogenase 8 | 1.1.1.62 | 0.709 | |
| 1ae1 | NAP | Tropinone reductase 1 | / | 0.708 | |
| 2yy7 | NAD | L-threonine dehydrogenase | / | 0.707 | |
| 3uxy | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.706 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.705 | |
| 4nbw | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.705 | |
| 4dqu | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.704 | |
| 3tox | NAP | Putative oxidoreductase | / | 0.701 | |
| 1ipe | NDP | Tropinone reductase 2 | 1.1.1.236 | 0.699 | |
| 1qyv | NAP | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.699 | |
| 3rud | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.699 | |
| 4fw8 | NAI | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.699 | |
| 1n2s | NAI | dTDP-4-dehydrorhamnose reductase | 1.1.1.133 | 0.697 | |
| 4yac | NAI | C alpha-dehydrogenase | / | 0.697 | |
| 3vdq | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.696 | |
| 3of2 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.695 | |
| 4bii | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.694 | |
| 2b4q | NAP | Rhamnolipids biosynthesis 3-oxoacyl-[acyl-carrier-protein] reductase | 1.1.1.100 | 0.693 | |
| 4rf2 | NAP | NADPH dependent R-specific alcohol dehydrogenase | / | 0.693 | |
| 1b2l | NDC | Alcohol dehydrogenase | 1.1.1.1 | 0.691 | |
| 1xkq | NDP | Uncharacterized protein | / | 0.691 | |
| 3oey | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.690 | |
| 3wmx | NAD | NAD dependent epimerase/dehydratase | / | 0.690 | |
| 5cpb | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.690 | |
| 1i2b | NAD | UDP-sulfoquinovose synthase, chloroplastic | 3.13.1.1 | 0.689 | |
| 2ztl | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.689 | |
| 3a1n | NAD | NDP-sugar epimerase | / | 0.688 | |
| 4k6f | NAP | Putative Acetoacetyl-CoA reductase | / | 0.688 | |
| 3o03 | NAP | Dehydrogenase with different specificities (Related to short-chain alcohol dehydrogenase) | / | 0.686 | |
| 4hxy | NDP | Plm1 | / | 0.686 | |
| 2aqh | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.684 | |
| 2nv6 | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.684 | |
| 2ztu | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.683 | |
| 3ndr | NAD | Pyridoxal 4-dehydrogenase | 1.1.1.107 | 0.683 | |
| 4bqp | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.682 | |
| 1b14 | NAD | Alcohol dehydrogenase | 1.1.1.1 | 0.681 | |
| 5jyd | NAD | Short chain dehydrogenase | / | 0.681 | |
| 2idz | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.680 | |
| 2x86 | NAP | ADP-L-glycero-D-manno-heptose-6-epimerase | / | 0.680 | |
| 4b8w | NAP | GDP-L-fucose synthase | 1.1.1.271 | 0.680 | |
| 3oew | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.678 | |
| 1p44 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.677 | |
| 4trn | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.677 | |
| 2p5u | NAD | UDP-glucose 4-epimerase | / | 0.676 | |
| 3ec7 | NAD | Inositol 2-dehydrogenase | / | 0.676 | |
| 5koi | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.676 | |
| 1kc1 | NDP | dTDP-4-dehydrorhamnose reductase | 1.1.1.133 | 0.675 | |
| 1xse | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.675 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.673 | |
| 4gll | NAD | UDP-glucuronic acid decarboxylase 1 | 4.1.1.35 | 0.673 | |
| 4lk3 | NAD | UDP-glucuronic acid decarboxylase 1 | 4.1.1.35 | 0.672 | |
| 3r3s | NAD | Putative oxidoreductase | / | 0.671 | |
| 4imp | NDP | Polyketide synthase extender modules 3-4 | / | 0.671 | |
| 1eny | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.670 | |
| 4clo | NAP | Pteridine reductase | / | 0.670 | |
| 2h9i | EAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.669 | |
| 2ntj | P1H | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.669 | |
| 3ehe | NAD | UDP-glucose 4-epimerase (GalE-1) | / | 0.669 | |
| 2ztm | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.668 | |
| 2z1m | NDP | GDP-mannose 4,6-dehydratase | / | 0.667 | |
| 2aqi | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.663 | |
| 4e5y | NDP | GDP-L-fucose synthase | 1.1.1.271 | 0.663 | |
| 1mp5 | UPG | Glucose-1-phosphate thymidylyltransferase | 2.7.7.24 | 0.662 | |
| 3wfj | NAD | 2-dehydropantoate 2-reductase | / | 0.662 | |
| 4dmm | NAP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.662 | |
| 2ewm | NAD | (S)-1-Phenylethanol dehydrogenase | 1.1.1.311 | 0.661 | |
| 2o4c | NAD | Erythronate-4-phosphate dehydrogenase | / | 0.661 | |
| 3h3j | NAD | L-lactate dehydrogenase 1 | 1.1.1.27 | 0.661 | |
| 3sj7 | NDP | 3-oxoacyl-(Acyl-carrier-protein) reductase, putative | / | 0.661 | |
| 4dti | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.661 | |
| 4idg | NAD | Putative UDP-glucose 4-epimerase | / | 0.661 | |
| 4y9d | NAI | C alpha-dehydrogenase | / | 0.661 | |
| 4yr9 | NAD | L-threonine 3-dehydrogenase, mitochondrial | 1.1.1.103 | 0.661 | |
| 4twr | NAD | NAD binding site:NAD-dependent epimerase/dehydratase:UDP-glucose 4-epimerase | / | 0.660 | |
| 1hdo | NAP | Flavin reductase (NADPH) | / | 0.659 | |
| 2aq8 | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.659 | |
| 4j4b | NAI | Uncharacterized protein | / | 0.659 | |
| 3uic | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.658 | |
| 4zju | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.658 | |
| 5d2e | NAP | MlnE | / | 0.658 | |
| 5lc1 | NAD | L-threonine 3-dehydrogenase | / | 0.658 | |
| 1jki | NAI | Inositol-3-phosphate synthase | 5.5.1.4 | 0.656 | |
| 1g1a | NAD | dTDP-glucose 4,6-dehydratase | / | 0.655 | |
| 1g6k | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.655 | |
| 4plp | NAD | Homospermidine synthase | 2.5.1.44 | 0.655 | |
| 2ieb | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.654 | |
| 2ntv | P1H | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.652 | |
| 4jbi | NDP | Alcohol dehydrogenase (Zinc) | / | 0.652 | |
| 1wvg | APR | CDP-glucose 4,6-dehydratase | 4.2.1.45 | 0.651 | |
| 2bgl | NAJ | Secoisolariciresinol dehydrogenase | 1.1.1.331 | 0.651 | |
| 2gn8 | NAP | UDP-N-acetylglucosamine 4,6-dehydratase (inverting) | 4.2.1.115 | 0.651 | |
| 3gvi | ADP | Malate dehydrogenase | / | 0.651 | |
| 3pvz | NAD | UDP-N-acetylglucosamine 4,6-dehydratase | / | 0.651 | |
| 3w6u | NAP | 6-phosphogluconate dehydrogenase, NAD-binding protein | / | 0.651 | |
| 4cuk | NAI | D-lactate dehydrogenase | / | 0.651 | |
| 1n7h | NDP | GDP-mannose 4,6 dehydratase 2 | 4.2.1.47 | 0.650 | |
| 2yqz | SAM | Uncharacterized protein | / | 0.650 |