sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4pao | GSP | Guanine nucleotide-binding protein G(i) subunit alpha-1 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 4pao | GSP | Guanine nucleotide-binding protein G(i) subunit alpha-1 | / | 1.000 | |
| 3ums | GDP | Guanine nucleotide-binding protein G(i) subunit alpha-1 | / | 0.601 | |
| 1gia | GSP | Guanine nucleotide-binding protein G(i) subunit alpha-1 | / | 0.594 | |
| 1azt | GSP | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | / | 0.581 | |
| 4pan | GDP | Guanine nucleotide-binding protein G(i) subunit alpha-1 | / | 0.577 | |
| 3vhx | GTP | ADP-ribosylation factor 6 | / | 0.574 | |
| 1gil | GSP | Guanine nucleotide-binding protein G(i) subunit alpha-1 | / | 0.566 | |
| 3c16 | GSP | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | / | 0.566 | |
| 3c15 | GSP | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | / | 0.559 | |
| 1cul | GSP | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | / | 0.544 | |
| 1y3a | GDP | Guanine nucleotide-binding protein G(i) subunit alpha-1 | / | 0.541 | |
| 4fid | GDP | G protein alpha subunit, putative | / | 0.505 | |
| 1gp2 | GDP | Guanine nucleotide-binding protein G(i) subunit alpha-1 | / | 0.501 | |
| 1got | GDP | Guanine nucleotide-binding protein G(t) subunit alpha-1 | / | 0.498 | |
| 3pcr | GTP | ADP-ribosylation factor 6 | / | 0.497 | |
| 1n6l | GTP | Ras-related protein Rab-5A | / | 0.496 | |
| 2ch6 | ADP | N-acetyl-D-glucosamine kinase | 2.7.1.59 | 0.486 | |
| 3tjz | GNP | ADP-ribosylation factor 1 | / | 0.485 | |
| 3tqa | NDP | Dihydrofolate reductase | / | 0.484 | |
| 2q3f | GNP | Ras-related GTP-binding protein D | / | 0.482 | |
| 4wda | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.482 | |
| 1ae1 | NAP | Tropinone reductase 1 | / | 0.479 | |
| 2fg5 | GNP | Ras-related protein Rab-31 | / | 0.479 | |
| 3cx6 | GDP | Guanine nucleotide-binding protein subunit alpha-13 | / | 0.479 | |
| 4jnk | ZHK | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.476 | |
| 5di3 | GNP | ADP-ribosylation factor-like protein 3 | / | 0.475 | |
| 2fe4 | GDP | Ras-related protein Rab-6B | / | 0.472 | |
| 2p9c | NAI | D-3-phosphoglycerate dehydrogenase | 1.1.1.95 | 0.472 | |
| 1zd9 | GDP | ADP-ribosylation factor-like protein 8A | / | 0.469 | |
| 2b69 | NAD | UDP-glucuronic acid decarboxylase 1 | 4.1.1.35 | 0.469 | |
| 1m2o | GNP | Small COPII coat GTPase SAR1 | 3.6.5 | 0.468 | |
| 4gyy | 12V | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.468 | |
| 1ky2 | GNP | GTP-binding protein YPT7 | / | 0.467 | |
| 3flk | NAI | Tartrate dehydrogenase/decarboxylase | 1.1.1.93 | 0.467 | |
| 4ozt | P1A | Ecdysone receptor, putative | / | 0.467 | |
| 1qf5 | RPL | Adenylosuccinate synthetase | / | 0.466 | |
| 3r9x | GNP | GTPase Era | / | 0.466 | |
| 4hdq | GNP | Ras-related protein Rap-1b | / | 0.466 | |
| 4wud | ANP | DNA gyrase subunit B | / | 0.466 | |
| 1f17 | NAI | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.465 | |
| 1mh1 | GNP | Ras-related C3 botulinum toxin substrate 1 | / | 0.465 | |
| 3d84 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.465 | |
| 3kyb | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.465 | |
| 4v02 | ATP | Site-determining protein | / | 0.465 | |
| 1drh | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.464 | |
| 4goj | GNP | ADP-ribosylation factor-like protein 3 | / | 0.464 | |
| 4o2r | GDP | GTP-binding protein Rheb | / | 0.464 | |
| 1nzd | UPG | DNA beta-glucosyltransferase | / | 0.463 | |
| 2hqp | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.462 | |
| 3oaf | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.462 | |
| 3s1d | ZIR | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.462 | |
| 4bqp | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.462 | |
| 4du8 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.462 | |
| 4wuj | FMN | Glycoside hydrolase family 15, cellulose signaling associated protein envoy | / | 0.462 | |
| 5ch7 | MD1 | DMSO reductase family type II enzyme, molybdopterin subunit | / | 0.462 | |
| 5k5z | ANP | Uncharacterized protein | / | 0.462 | |
| 2z6c | FMN | Phototropin-1 | 2.7.11.1 | 0.461 | |
| 4c04 | SFG | Protein arginine N-methyltransferase 6 | / | 0.461 | |
| 1rj9 | GCP | Signal recognition particle receptor FtsY | / | 0.460 | |
| 4e8y | IHA | D-beta-D-heptose 7-phosphate kinase | / | 0.460 | |
| 4lj9 | ACP | Chaperone protein ClpB | / | 0.460 | |
| 1ykf | NAP | NADP-dependent isopropanol dehydrogenase | 1.1.1.80 | 0.459 | |
| 2hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.459 | |
| 1cg1 | IMO | Adenylosuccinate synthetase | / | 0.458 | |
| 1ha3 | MAU | Elongation factor Tu-A | / | 0.458 | |
| 1juv | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.458 | |
| 2cy0 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.458 | |
| 3gon | ANP | Phosphomevalonate kinase | / | 0.458 | |
| 4jld | ADP | Adenylate kinase | / | 0.458 | |
| 4wuc | ANP | DNA gyrase subunit B | / | 0.458 | |
| 2c59 | NAD | GDP-mannose 3,5-epimerase | 5.1.3.18 | 0.457 | |
| 4e07 | ACP | Plasmid partitioning protein ParF | / | 0.457 | |
| 4l4x | NDP | AmphI | / | 0.457 | |
| 1adf | TAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.456 | |
| 1dr3 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.456 | |
| 1oix | GDP | Ras-related protein Rab-11A | / | 0.456 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.456 | |
| 2y0m | ACO | Histone acetyltransferase KAT8 | / | 0.456 | |
| 2z54 | AB1 | Gag-Pol polyprotein | 3.4.23.16 | 0.456 | |
| 4an4 | DUD | Putative glycosyl transferase | / | 0.456 | |
| 5a4k | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.456 | |
| 3kko | GNP | Ras-related protein M-Ras | / | 0.455 | |
| 3up4 | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.455 | |
| 4zir | ANP | Energy-coupling factor transporter ATP-binding protein EcfA2 | 3.6.3 | 0.455 | |
| 4zir | ANP | Energy-coupling factor transporter ATP-binding protein EcfA1 | / | 0.455 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.454 | |
| 1qf4 | RPD | Adenylosuccinate synthetase | / | 0.454 | |
| 2ggs | NDP | dTDP-4-dehydrorhamnose reductase | / | 0.454 | |
| 2y9q | ANP | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.454 | |
| 3f1k | NAP | Uncharacterized oxidoreductase YciK | 1 | 0.454 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.454 | |
| 1dg8 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 1kvk | ATP | Mevalonate kinase | 2.7.1.36 | 0.453 | |
| 2pd7 | FAD | Vivid PAS protein VVD | / | 0.453 | |
| 2wo7 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.453 | |
| 3h6v | NS6 | Glutamate receptor 2 | / | 0.453 | |
| 3juq | AJD | Phenazine biosynthesis protein A/B | / | 0.453 | |
| 4bbx | LKF | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.453 | |
| 4j7u | NAP | Sepiapterin reductase | 1.1.1.153 | 0.453 | |
| 5br7 | FAD | UDP-galactopyranose mutase | / | 0.453 | |
| 3b6z | CO7 | Enoyl reductase LovC | 1 | 0.452 | |
| 3clu | FAD | Electron transfer flavoprotein subunit alpha | / | 0.452 | |
| 3nxx | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 4fv6 | E57 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.452 | |
| 4hj6 | FMN | LOV protein | / | 0.452 | |
| 1me6 | IVS | Plasmepsin-2 | 3.4.23.39 | 0.451 | |
| 2j5x | GSP | ADP-ribosylation factor 6 | / | 0.451 | |
| 2pr5 | FMN | Blue-light photoreceptor | / | 0.451 | |
| 3r83 | Z14 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.451 | |
| 4dpu | AGS | Mevalonate diphosphate decarboxylase | / | 0.451 | |
| 4dxh | NAJ | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.451 | |
| 4ew2 | DXY | Trifunctional purine biosynthetic protein adenosine-3 | 2.1.2.2 | 0.451 | |
| 4gh5 | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.451 | |
| 4hia | FMN | LOV protein | / | 0.451 | |
| 5a3c | NAD | SIR2 family protein | / | 0.451 | |
| 1h47 | C5P | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | 4.6.1.12 | 0.450 | |
| 1ksz | PGS | Adenylosuccinate synthetase | / | 0.450 | |
| 1o0s | NAI | NAD-dependent malic enzyme, mitochondrial | 1.1.1.38 | 0.450 | |
| 2xpv | MIY | Tetracycline repressor protein class D | / | 0.450 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.450 | |
| 4fj1 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.450 | |
| 4mih | FAD | Pyranose 2-oxidase | 1.1.3.10 | 0.450 | |
| 4pd6 | URI | Nucleoside permease | / | 0.450 | |
| 4rvn | COA | Phenylacetate-coenzyme A ligase | / | 0.450 | |
| 1bdl | IM1 | Gag-Pol polyprotein | 3.4.23.16 | 0.449 | |
| 1hdr | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.449 | |
| 1svw | GTP | Probable GTP-binding protein EngB | / | 0.449 | |
| 1yu9 | GNP | Ras-related protein Rab-4A | / | 0.449 | |
| 2nn7 | M29 | Carbonic anhydrase 1 | 4.2.1.1 | 0.449 | |
| 3r6c | 17N | Anthranilate phosphoribosyltransferase | / | 0.449 | |
| 4eo3 | FMN | Bacterioferritin comigratory protein/NADH dehydrogenase | / | 0.449 | |
| 4hmv | WUB | Phenazine biosynthesis protein PhzG | 1.4 | 0.449 | |
| 1h5q | NAP | NADP-dependent mannitol dehydrogenase | 1.1.1.138 | 0.448 | |
| 1njf | ADP | DNA polymerase III subunit tau | 2.7.7.7 | 0.448 | |
| 1q0q | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | 1.1.1.267 | 0.448 | |
| 2dgn | DOI | Adenylosuccinate synthetase isozyme 1 | / | 0.448 | |
| 2fjd | SFD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.448 | |
| 2giv | ACO | Histone acetyltransferase KAT8 | / | 0.448 | |
| 2wns | OMP | Uridine 5'-monophosphate synthase | 2.4.2.10 | 0.448 | |
| 2xrl | DXT | Tetracycline repressor protein class D | / | 0.448 | |
| 4cid | ANP | EH domain-containing protein 2 | / | 0.448 | |
| 4ewn | 0VR | Imidazole glycerol phosphate synthase subunit HisF | 4.1.3 | 0.448 | |
| 4g95 | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 1dir | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.447 | |
| 1dr3 | HBI | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 1z0d | GDP | Ras-related protein Rab-5C | / | 0.447 | |
| 1zw1 | TN5 | Enoyl-ACP reductase | / | 0.447 | |
| 2fn7 | NAD | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.447 | |
| 2pa3 | NAI | D-3-phosphoglycerate dehydrogenase | 1.1.1.95 | 0.447 | |
| 2r6g | ATP | Maltose/maltodextrin import ATP-binding protein MalK | / | 0.447 | |
| 3nbv | ANP | Ketohexokinase | / | 0.447 | |
| 4o63 | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.447 | |
| 4ure | 1PS | Cyclohexanol dehydrogenase | / | 0.447 | |
| 1x1r | GDP | Ras-related protein M-Ras | / | 0.446 | |
| 1y7u | COA | Acyl-CoA hydrolase | / | 0.446 | |
| 2jkv | NAP | 6-phosphogluconate dehydrogenase, decarboxylating | 1.1.1.44 | 0.446 | |
| 2w9h | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 2ztm | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.446 | |
| 3nl6 | TPS | Uncharacterized protein | / | 0.446 | |
| 3p2e | SAH | 16S rRNA (adenine(1408)-N(1))-methyltransferase | 2.1.1.180 | 0.446 | |
| 3w2e | NAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.446 | |
| 4fv7 | E94 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.446 | |
| 4ji9 | 1M3 | Tyrosine-protein kinase JAK2 | / | 0.446 | |
| 4ydd | MD1 | DMSO reductase family type II enzyme, molybdopterin subunit | / | 0.446 | |
| 1ju9 | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.445 | |
| 1nht | PGS | Adenylosuccinate synthetase | / | 0.445 | |
| 1xnj | ADP | Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1 | 2.7.1.25 | 0.445 | |
| 2aa0 | MTP | Adenosine kinase | 2.7.1.20 | 0.445 | |
| 2hfu | MEV | Mevalonate kinase | / | 0.445 | |
| 2qbu | SAH | Precorrin-2 methyltransferase | / | 0.445 | |
| 3cvu | FAD | RE11660p | / | 0.445 | |
| 3d3w | NAP | L-xylulose reductase | 1.1.1.10 | 0.445 | |
| 3f03 | FMN | Pentaerythritol tetranitrate reductase | / | 0.445 | |
| 3ge1 | ADP | Glycerol kinase | / | 0.445 | |
| 3had | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.445 | |
| 3is2 | FAD | Vivid PAS protein VVD | / | 0.445 | |
| 3kga | LX9 | MAP kinase-activated protein kinase 2 | 2.7.11.1 | 0.445 | |
| 3p7n | FMN | Light-activated DNA-binding protein EL222 | / | 0.445 | |
| 4iqg | NAP | Short-chain dehydrogenase/reductase SDR | / | 0.445 | |
| 4obu | PLP | Pyridoxal-dependent decarboxylase domain protein | / | 0.445 | |
| 5kcz | NAJ | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.445 | |
| 1j39 | UPG | DNA beta-glucosyltransferase | / | 0.444 | |
| 1t0l | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.444 | |
| 2fj1 | CTC | Tetracycline repressor protein class D | / | 0.444 | |
| 3bhi | NAP | Carbonyl reductase [NADPH] 1 | 1.1.1.184 | 0.444 | |
| 3dga | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.444 | |
| 3jvv | ACP | Twitching mobility protein | / | 0.444 | |
| 3mje | NDP | AmphB | / | 0.444 | |
| 3vfq | AR6 | Poly [ADP-ribose] polymerase 14 | 2.4.2.30 | 0.444 | |
| 4hwk | NAP | Sepiapterin reductase | 1.1.1.153 | 0.444 | |
| 4nd4 | NAD | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.444 | |
| 1i8t | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.443 | |
| 1mei | XMP | Inosine-5'-monophosphate dehydrogenase | / | 0.443 | |
| 1siq | FAD | Glutaryl-CoA dehydrogenase, mitochondrial | 1.3.8.6 | 0.443 | |
| 1v0j | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.443 | |
| 1zxm | ANP | DNA topoisomerase 2-alpha | 5.99.1.3 | 0.443 | |
| 2chz | 093 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.443 | |
| 2j3j | HC4 | NADPH-dependent oxidoreductase 2-alkenal reductase | 1.3.1.74 | 0.443 | |
| 2yit | YIT | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.443 | |
| 3hk1 | B64 | Fatty acid-binding protein, adipocyte | / | 0.443 | |
| 3rm6 | 18Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.443 | |
| 4die | C5P | Cytidylate kinase | / | 0.443 | |
| 4fc7 | NAP | Peroxisomal 2,4-dienoyl-CoA reductase | 1.3.1.34 | 0.443 | |
| 4lrj | ANP | Uncharacterized protein | / | 0.443 | |
| 4m10 | ICD | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.443 | |
| 1cs4 | FOK | Adenylate cyclase type 2 | / | 0.442 | |
| 1cs4 | FOK | Adenylate cyclase type 5 | / | 0.442 | |
| 1drf | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1k5d | GNP | GTP-binding nuclear protein Ran | / | 0.442 | |
| 1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
| 2a94 | AP0 | L-lactate dehydrogenase | 1.1.1.27 | 0.442 | |
| 2bue | COA | AAC(6')-Ib | / | 0.442 | |
| 2c29 | NAP | Dihydroflavonol 4-reductase | / | 0.442 | |
| 2w0j | ZAT | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.442 | |
| 2ylz | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.442 | |
| 3fuf | BES | Leukotriene A-4 hydrolase | 3.3.2.6 | 0.442 | |
| 3itz | P66 | Mitogen-activated protein kinase 14 | / | 0.442 | |
| 3lfm | 3DT | Alpha-ketoglutarate-dependent dioxygenase FTO | / | 0.442 | |
| 3pb3 | SAH | 16S rRNA (adenine(1408)-N(1))-methyltransferase | 2.1.1.180 | 0.442 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.442 | |
| 4c8e | C5P | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | / | 0.442 | |
| 4cvl | ACP | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase | / | 0.442 | |
| 4e8w | IHA | D-beta-D-heptose 7-phosphate kinase | / | 0.442 | |
| 4jky | ADP | Adenylate kinase | / | 0.442 | |
| 4tlb | AGS | Circadian clock protein kinase KaiC | 2.7.11.1 | 0.442 | |
| 5kjf | NAJ | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.442 | |
| 1cg0 | IMO | Adenylosuccinate synthetase | / | 0.441 | |
| 1kor | ANP | Argininosuccinate synthase | / | 0.441 | |
| 2rcy | NAP | Pyrroline-5-carboxylate reductase | / | 0.441 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.441 | |
| 3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.441 | |
| 3etd | NDP | Glutamate dehydrogenase 1, mitochondrial | 1.4.1.3 | 0.441 | |
| 3fvl | BHK | Carboxypeptidase A1 | 3.4.17.1 | 0.441 | |
| 3mpt | 1GK | Mitogen-activated protein kinase 14 | / | 0.441 | |
| 3pj8 | 404 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.441 | |
| 3r6s | CMP | CRP-like cAMP-activated global transcriptional regulator | / | 0.441 | |
| 3sdk | P3N | Proteasome subunit beta type-5 | 3.4.25.1 | 0.441 | |
| 3sdk | P3N | Proteasome subunit beta type-6 | 3.4.25.1 | 0.441 | |
| 3vsw | R31 | Renin | 3.4.23.15 | 0.441 | |
| 4bcr | WY1 | Peroxisome proliferator-activated receptor alpha | / | 0.441 | |
| 4f65 | 0S9 | Fibroblast growth factor receptor 1 | / | 0.441 | |
| 4h3c | 0YZ | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.441 | |
| 4hs4 | FMN | Chromate reductase | / | 0.441 | |
| 4l7f | 1V5 | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.441 | |
| 4y0v | GDP | ADP-ribosylation factor 1, putative | / | 0.441 | |
| 1dr2 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 1orr | NAD | CDP-paratose 2-epimerase | / | 0.440 | |
| 1z2a | GDP | Ras-related protein Rab-23 | / | 0.440 | |
| 1z7y | AA5 | Cysteine synthase 1 | 2.5.1.47 | 0.440 | |
| 2ym1 | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.440 | |
| 3b2s | B2S | Trichothecene 3-O-acetyltransferase | / | 0.440 | |
| 3b70 | NAP | Enoyl reductase LovC | 1 | 0.440 | |
| 3k4c | FAD | Pyranose 2-oxidase | / | 0.440 | |
| 3ozd | 4CT | S-methyl-5'-thioadenosine phosphorylase | / | 0.440 | |
| 3t50 | FMN | Blue-light-activated histidine kinase | 2.7.13.3 | 0.440 | |
| 3u9e | COA | Lmo1369 protein | / | 0.440 | |
| 3u9f | CLM | Chloramphenicol acetyltransferase | 2.3.1.28 | 0.440 | |
| 4bdf | H3R | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.440 | |
| 4jal | SAH | tRNA (cytidine(34)-2'-O)-methyltransferase | / | 0.440 | |
| 4l2i | FAD | Electron transfer flavoprotein alpha/beta-subunit | / | 0.440 | |
| 4xgx | ADP | FAD:protein FMN transferase | / | 0.440 | |
| 5cdt | NAJ | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.440 | |
| 5dp2 | NAP | CurF | / | 0.440 |