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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3rk708ZCyclin-dependent kinase 22.7.11.22

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
3rk708ZCyclin-dependent kinase 22.7.11.221.000
3qzgX67Cyclin-dependent kinase 22.7.11.220.640
3rk507ZCyclin-dependent kinase 22.7.11.220.623
3rk909ZCyclin-dependent kinase 22.7.11.220.612
2xmyCDKCyclin-dependent kinase 22.7.11.220.599
3qu0X40Cyclin-dependent kinase 22.7.11.220.594
3rni21ZCyclin-dependent kinase 22.7.11.220.593
3qtxX43Cyclin-dependent kinase 22.7.11.220.590
3rpv26ZCyclin-dependent kinase 22.7.11.220.587
4fkg4CKCyclin-dependent kinase 22.7.11.220.583
1y91CT9Cyclin-dependent kinase 22.7.11.220.582
3rmf20ZCyclin-dependent kinase 22.7.11.220.579
3rjc06ZCyclin-dependent kinase 22.7.11.220.577
3lfnA27Cyclin-dependent kinase 22.7.11.220.573
1g5sI17Cyclin-dependent kinase 22.7.11.220.569
3r8lZ30Cyclin-dependent kinase 22.7.11.220.568
1pxlCK4Cyclin-dependent kinase 22.7.11.220.566
3rak03ZCyclin-dependent kinase 22.7.11.220.565
1ykr628Cyclin-dependent kinase 22.7.11.220.564
3s1h56ZCyclin-dependent kinase 22.7.11.220.560
4fkv61KCyclin-dependent kinase 22.7.11.220.557
3r73X87Cyclin-dependent kinase 22.7.11.220.556
4ek816KCyclin-dependent kinase 22.7.11.220.553
3qtrX36Cyclin-dependent kinase 22.7.11.220.552
2b52D42Cyclin-dependent kinase 22.7.11.220.549
3qqkX02Cyclin-dependent kinase 22.7.11.220.549
2r3kSCQCyclin-dependent kinase 22.7.11.220.548
3lfqA28Cyclin-dependent kinase 22.7.11.220.545
3rpo24ZCyclin-dependent kinase 22.7.11.220.545
1gih1PUCyclin-dependent kinase 22.7.11.220.543
3ral04ZCyclin-dependent kinase 22.7.11.220.543
2c6o4SPCyclin-dependent kinase 22.7.11.220.542
2vtoLZ8Cyclin-dependent kinase 22.7.11.220.542
4ek610KCyclin-dependent kinase 22.7.11.220.542
4fkj11KCyclin-dependent kinase 22.7.11.220.539
2w06FRVCyclin-dependent kinase 22.7.11.220.538
2w1hL0FCyclin-dependent kinase 22.7.11.220.538
3qtwX3ACyclin-dependent kinase 22.7.11.220.538
1aq1STUCyclin-dependent kinase 22.7.11.220.537
1oirHDYCyclin-dependent kinase 22.7.11.220.536
2a0cCK9Cyclin-dependent kinase 22.7.11.220.536
2vtjLZ4Cyclin-dependent kinase 22.7.11.220.535
3iggEFQCyclin-dependent kinase 22.7.11.220.535
3py0SU9Cyclin-dependent kinase 22.7.11.220.535
3r7yZ04Cyclin-dependent kinase 22.7.11.220.533
4acm7YGCyclin-dependent kinase 22.7.11.220.533
2uznC96Cyclin-dependent kinase 22.7.11.220.532
2uzoC62Cyclin-dependent kinase 22.7.11.220.532
1pxoCK7Cyclin-dependent kinase 22.7.11.220.531
3qwjX6ACyclin-dependent kinase 22.7.11.220.530
3sw418KCyclin-dependent kinase 22.7.11.220.528
4fki09KCyclin-dependent kinase 22.7.11.220.528
1ke5LS1Cyclin-dependent kinase 22.7.11.220.527
3ql8X01Cyclin-dependent kinase 22.7.11.220.527
3qqfX07Cyclin-dependent kinase 22.7.11.220.527
3r71X86Cyclin-dependent kinase 22.7.11.220.527
4fkr45KCyclin-dependent kinase 22.7.11.220.527
3r1yX76Cyclin-dependent kinase 22.7.11.220.526
1pxmCK5Cyclin-dependent kinase 22.7.11.220.525
2vtrLZBCyclin-dependent kinase 22.7.11.220.525
3sqq99ZCyclin-dependent kinase 22.7.11.220.525
2vv9IM9Cyclin-dependent kinase 22.7.11.220.524
4fks46KCyclin-dependent kinase 22.7.11.220.524
2btrU73Cyclin-dependent kinase 22.7.11.220.523
3r8vZ62Cyclin-dependent kinase 22.7.11.220.523
1oitHDTCyclin-dependent kinase 22.7.11.220.520
3sw719KCyclin-dependent kinase 22.7.11.220.519
2w17I19Cyclin-dependent kinase 22.7.11.220.518
3qtuX44Cyclin-dependent kinase 22.7.11.220.518
4fkt48KCyclin-dependent kinase 22.7.11.220.518
1ke9LS5Cyclin-dependent kinase 22.7.11.220.517
2vtsLZCCyclin-dependent kinase 22.7.11.220.517
1h1s4SPCyclin-dependent kinase 22.7.11.220.516
3wblPDYCyclin-dependent kinase 22.7.11.220.516
2r3jSCJCyclin-dependent kinase 22.7.11.220.514
2vtpLZ9Cyclin-dependent kinase 22.7.11.220.513
4fkq42KCyclin-dependent kinase 22.7.11.220.511
1w0xOLOCyclin-dependent kinase 22.7.11.220.510
3s0o50ZCyclin-dependent kinase 22.7.11.220.510
2btsU32Cyclin-dependent kinase 22.7.11.220.509
2vtnLZ7Cyclin-dependent kinase 22.7.11.220.509
2vthLZ2Cyclin-dependent kinase 22.7.11.220.508
3r1sX73Cyclin-dependent kinase 22.7.11.220.508
2vtiLZ3Cyclin-dependent kinase 22.7.11.220.507
1pyePM1Cyclin-dependent kinase 22.7.11.220.506
3r9hZ67Cyclin-dependent kinase 22.7.11.220.506
4fkw62KCyclin-dependent kinase 22.7.11.220.506
1p2a5BNCyclin-dependent kinase 22.7.11.220.504
2a4lRRCCyclin-dependent kinase 22.7.11.220.504
1ke6LS2Cyclin-dependent kinase 22.7.11.220.503
2vttLZDCyclin-dependent kinase 22.7.11.220.503
4fko20KCyclin-dependent kinase 22.7.11.220.503
2c6kDT2Cyclin-dependent kinase 22.7.11.220.501
2r3lSCWCyclin-dependent kinase 22.7.11.220.501
3r83Z14Cyclin-dependent kinase 22.7.11.220.501
4bgh3I6Cyclin-dependent kinase 22.7.11.220.501
4fkpLS5Cyclin-dependent kinase 22.7.11.220.501
1ke7LS3Cyclin-dependent kinase 22.7.11.220.498
1urwI1PCyclin-dependent kinase 22.7.11.220.498
2duv371Cyclin-dependent kinase 22.7.11.220.498
2ds11CDCyclin-dependent kinase 22.7.11.220.495
3qzhX69Cyclin-dependent kinase 22.7.11.220.494
3ti1B49Cyclin-dependent kinase 22.7.11.220.494
2b53D23Cyclin-dependent kinase 22.7.11.220.493
2iw94SPCyclin-dependent kinase 22.7.11.220.492
4eon1ROCyclin-dependent kinase 22.7.11.220.492
1oguST8Cyclin-dependent kinase 22.7.11.220.491
3qtzX42Cyclin-dependent kinase 22.7.11.220.491
3s2pPMUCyclin-dependent kinase 22.7.11.220.490
1di8DTQCyclin-dependent kinase 22.7.11.220.489
3qqlX03Cyclin-dependent kinase 22.7.11.220.489
3r9oZ71Cyclin-dependent kinase 22.7.11.220.489
3rpy27ZCyclin-dependent kinase 22.7.11.220.489
4fx360KCyclin-dependent kinase 22.7.11.220.489
1h1r6CPCyclin-dependent kinase 22.7.11.220.487
1oiyN41Cyclin-dependent kinase 22.7.11.220.487
1y8yCT7Cyclin-dependent kinase 22.7.11.220.487
3ig7EFPCyclin-dependent kinase 22.7.11.220.487
3r8zZ63Cyclin-dependent kinase 22.7.11.220.487
3fz1B98Cyclin-dependent kinase 22.7.11.220.486
3r8pZ46Cyclin-dependent kinase 22.7.11.220.486
1hckATPCyclin-dependent kinase 22.7.11.220.485
1ckpPVBCyclin-dependent kinase 22.7.11.220.484
2exmZIPCyclin-dependent kinase 22.7.11.220.484
3rm618ZCyclin-dependent kinase 22.7.11.220.483
3unk0BYCyclin-dependent kinase 22.7.11.220.483
1b38ATPCyclin-dependent kinase 22.7.11.220.482
1dm2HMDCyclin-dependent kinase 22.7.11.220.482
2uzeC95Cyclin-dependent kinase 22.7.11.220.482
4kd11QKCyclin-dependent kinase 22.7.11.220.482
1e1xNW1Cyclin-dependent kinase 22.7.11.220.481
2eufLQQCyclin-dependent kinase 62.7.11.220.480
3r6xX84Cyclin-dependent kinase 22.7.11.220.480
3qxoX65Cyclin-dependent kinase 22.7.11.220.479
4ez30S0Cyclin-dependent kinase 22.7.11.220.478
2bhhRYUCyclin-dependent kinase 22.7.11.220.477
3r7eX88Cyclin-dependent kinase 22.7.11.220.477
3r7uX96Cyclin-dependent kinase 22.7.11.220.477
3rahO1ZCyclin-dependent kinase 22.7.11.220.477
2b54D05Cyclin-dependent kinase 22.7.11.220.476
4eor4SPCyclin-dependent kinase 22.7.11.220.476
3ddpRC8Cyclin-dependent kinase 22.7.11.220.475
3qwkX62Cyclin-dependent kinase 22.7.11.220.475
4eok4SPCyclin-dependent kinase 22.7.11.220.475
3qtqX35Cyclin-dependent kinase 22.7.11.220.472
4fklCK2Cyclin-dependent kinase 22.7.11.220.472
1pxpCK8Cyclin-dependent kinase 22.7.11.220.471
3r1qX75Cyclin-dependent kinase 22.7.11.220.470
1fvv107Cyclin-dependent kinase 22.7.11.220.469
3roy22ZCyclin-dependent kinase 22.7.11.220.468
2b55D31Cyclin-dependent kinase 22.7.11.220.466
1gii1PUCyclin-dependent kinase 22.7.11.220.465
2iw84SPCyclin-dependent kinase 22.7.11.220.465
2pvnP63Casein kinase II subunit alpha2.7.11.10.465
3ddqRRCCyclin-dependent kinase 22.7.11.220.465
1h0w207Cyclin-dependent kinase 22.7.11.220.464
2c6tDT5Cyclin-dependent kinase 22.7.11.220.464
2x1nX1NCyclin-dependent kinase 22.7.11.220.464
4lyn1YGCyclin-dependent kinase 22.7.11.220.464
1vyw292Cyclin-dependent kinase 22.7.11.220.463
1vyzN5BCyclin-dependent kinase 22.7.11.220.463
2r3p3SCCyclin-dependent kinase 22.7.11.220.462
3qrtX14Cyclin-dependent kinase 22.7.11.220.461
3r28XA0Cyclin-dependent kinase 22.7.11.220.461
2vz6FEFCalcium/calmodulin-dependent protein kinase type II subunit alpha2.7.11.170.459
3qx4X4BCyclin-dependent kinase 22.7.11.220.459
1fvt106Cyclin-dependent kinase 22.7.11.220.458
3qx2X63Cyclin-dependent kinase 22.7.11.220.458
3sheI85MAP kinase-activated protein kinase 32.7.11.10.458
2c5nCK8Cyclin-dependent kinase 22.7.11.220.457
2xnbY8LCyclin-dependent kinase 22.7.11.220.457
1gij2PUCyclin-dependent kinase 22.7.11.220.456
1pkdUCNCyclin-dependent kinase 22.7.11.220.456
2c6lDT4Cyclin-dependent kinase 22.7.11.220.456
2uzlC94Cyclin-dependent kinase 22.7.11.220.456
3unj0BXCyclin-dependent kinase 22.7.11.220.456
1pxkCK3Cyclin-dependent kinase 22.7.11.220.454
3lfsA07Cyclin-dependent kinase 22.7.11.220.454
3pj8404Cyclin-dependent kinase 22.7.11.220.454
3raiX85Cyclin-dependent kinase 22.7.11.220.454
3ezvEZVCyclin-dependent kinase 22.7.11.220.452
1w8cN69Cyclin-dependent kinase 22.7.11.220.451
2cchATPCyclin-dependent kinase 22.7.11.220.450
4qmpDKISerine/threonine-protein kinase 242.7.11.10.450
2i40BLZCyclin-dependent kinase 22.7.11.220.449
1vjy460TGF-beta receptor type-12.7.11.300.448
4nj32KDCyclin-dependent kinase 22.7.11.220.448
2b9jADPMitogen-activated protein kinase FUS32.7.11.240.447
2iw6QQ2Cyclin-dependent kinase 22.7.11.220.447
3nynSGVG protein-coupled receptor kinase 62.7.11.160.446
1ke8LS4Cyclin-dependent kinase 22.7.11.220.444
3bhtMFRCyclin-dependent kinase 22.7.11.220.443
2wihP48Cyclin-dependent kinase 22.7.11.220.442
3qruX19Cyclin-dependent kinase 22.7.11.220.442
3tnwF18Cyclin-dependent kinase 22.7.11.220.442
4cfnJYMCyclin-dependent kinase 22.7.11.220.442
1oiuN76Cyclin-dependent kinase 22.7.11.220.441
4eomATPCyclin-dependent kinase 22.7.11.220.441
3pxyJWSCyclin-dependent kinase 22.7.11.220.440
4anmWULCasein kinase II subunit alpha2.7.11.10.440
4gih0X5Non-receptor tyrosine-protein kinase TYK22.7.10.20.440