sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4c9p | CAM | Cytochrome P450 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 4c9p | CAM | Cytochrome P450 | / | 1.000 | |
| 3lxi | CAM | Cytochrome P450 | / | 0.672 | |
| 2a1m | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.648 | |
| 1t88 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.641 | |
| 1t87 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.639 | |
| 1dz6 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.634 | |
| 2cpp | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.631 | |
| 1o76 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.628 | |
| 4g3r | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.628 | |
| 4l4a | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.626 | |
| 1yrd | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.625 | |
| 1dz8 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.624 | |
| 1noo | CAH | Camphor 5-monooxygenase | 1.14.15.1 | 0.621 | |
| 5cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.621 | |
| 4cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.619 | |
| 1iwj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.618 | |
| 3fwg | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.617 | |
| 4c9o | CAM | Cytochrome P450 | / | 0.617 | |
| 1iwi | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.616 | |
| 2z97 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.616 | |
| 3wrh | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.616 | |
| 4l4c | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.616 | |
| 2a1n | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.615 | |
| 4l4b | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.613 | |
| 2m56 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.612 | |
| 1t85 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.611 | |
| 3fwf | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.611 | |
| 4kky | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.611 | |
| 4l49 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.610 | |
| 4l4d | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.610 | |
| 1phg | MYT | Camphor 5-monooxygenase | 1.14.15.1 | 0.609 | |
| 1dz4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.608 | |
| 3fwj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.608 | |
| 3fwi | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.607 | |
| 3wrl | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.606 | |
| 1t86 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.603 | |
| 2zaw | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.602 | |
| 3l63 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.602 | |
| 1yrc | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.601 | |
| 2feu | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.601 | |
| 2zax | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.600 | |
| 3wrm | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.599 | |
| 3wrj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.598 | |
| 6cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.598 | |
| 3cpp | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.597 | |
| 2qbl | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.596 | |
| 2qbm | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.594 | |
| 4ek1 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.594 | |
| 2qbo | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.592 | |
| 2a1o | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.587 | |
| 2qbn | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.586 | |
| 1uyu | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.583 | |
| 1geb | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.579 | |
| 4l4f | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.578 | |
| 4jx1 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.576 | |
| 4jx1 | CAH | Camphor 5-monooxygenase | 1.14.15.1 | 0.572 | |
| 4l4e | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.572 | |
| 1phe | PIY | Camphor 5-monooxygenase | 1.14.15.1 | 0.549 | |
| 3p6o | ETG | Camphor 5-monooxygenase | 1.14.15.1 | 0.544 | |
| 4tuv | CPZ | Cytochrome P450 119 | 1.14 | 0.538 | |
| 2zui | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.532 | |
| 4nky | 3QZ | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.518 | |
| 3mdm | FJZ | Cholesterol 24-hydroxylase | / | 0.515 | |
| 4enh | FVX | Cholesterol 24-hydroxylase | / | 0.513 | |
| 3mdv | CL6 | Cholesterol 24-hydroxylase | / | 0.509 | |
| 3ruk | AER | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.507 | |
| 3t3r | 9PL | Cytochrome P450 2A6 | 1.14.13 | 0.506 | |
| 5hs1 | VOR | Lanosterol 14-alpha demethylase | / | 0.506 | |
| 4lht | CNL | 1,8-cineole 2-endo-monooxygenase | 1.14.13.156 | 0.503 | |
| 1jio | DEB | 6-deoxyerythronolide B hydroxylase | / | 0.502 | |
| 4ejh | 0QA | Cytochrome P450 2A13 | 1.14.14.1 | 0.501 | |
| 3tk3 | CPZ | Cytochrome P450 2B4 | 1.14.14.1 | 0.500 | |
| 4nkv | AER | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.497 | |
| 3p99 | LNP | Lanosterol 14-alpha-demethylase | / | 0.496 | |
| 1jip | KTN | 6-deoxyerythronolide B hydroxylase | / | 0.493 | |
| 1suo | CPZ | Cytochrome P450 2B4 | 1.14.14.1 | 0.489 | |
| 2w0b | CMW | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.489 | |
| 4ia3 | BIV | Vitamin D3 receptor A | / | 0.488 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.485 | |
| 3ibd | CPZ | Cytochrome P450 2B6 | 1.14.13 | 0.485 | |
| 4y8w | STR | Steroid 21-hydroxylase | / | 0.484 | |
| 1t2b | CNL | 1,8-cineole 2-endo-monooxygenase | 1.14.13.156 | 0.483 | |
| 4uym | VOR | 14-alpha sterol demethylase Cyp51B | / | 0.483 | |
| 4j6c | STR | Cytochrome P450 monooxygenase | / | 0.482 | |
| 4r20 | AER | Cytochrome P450 family 17 polypeptide 2 | / | 0.481 | |
| 3pb3 | SAH | 16S rRNA (adenine(1408)-N(1))-methyltransferase | 2.1.1.180 | 0.479 | |
| 3s79 | ASD | Aromatase | 1.14.14.14 | 0.479 | |
| 2vn0 | TDZ | Cytochrome P450 2C8 | / | 0.477 | |
| 3gxo | MQA | Mitomycin biosynthesis 6-O-methyltransferase | / | 0.477 | |
| 4l6g | CNL | 1,8-cineole 2-endo-monooxygenase | 1.14.13.156 | 0.477 | |
| 1eup | ASD | 6-deoxyerythronolide B hydroxylase | / | 0.475 | |
| 2x7g | PVB | SRSF protein kinase 2 | 2.7.11.1 | 0.475 | |
| 3a1l | 2CC | Cytochrome P450 | / | 0.473 | |
| 3nr4 | PYV | Abscisic acid receptor PYL2 | / | 0.472 | |
| 1ouk | 084 | Mitogen-activated protein kinase 14 | / | 0.470 | |
| 2nnh | REA | Cytochrome P450 2C8 | / | 0.470 | |
| 2y3s | TIR | TamL | / | 0.469 | |
| 3t3q | 9PL | Cytochrome P450 2A6 | 1.14.13 | 0.469 | |
| 3irm | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.468 | |
| 4k9v | 6AW | Cytochrome P450 3A4 | / | 0.468 | |
| 4fmx | CNL | 1,8-cineole 2-endo-monooxygenase | 1.14.13.156 | 0.467 | |
| 4qq3 | XMP | Inosine-5'-monophosphate dehydrogenase | / | 0.467 | |
| 3ns2 | PYV | Abscisic acid receptor PYL2 | / | 0.466 | |
| 4fjz | 4FJ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.466 | |
| 1dg5 | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.465 | |
| 4q72 | FAD | Bifunctional protein PutA | / | 0.465 | |
| 5c8w | PCG | cGMP-dependent protein kinase 2 | 2.7.11.12 | 0.465 | |
| 3kdj | A8S | Abscisic acid receptor PYL1 | / | 0.464 | |
| 3tjs | D0R | Cytochrome P450 3A4 | / | 0.464 | |
| 4ia7 | BIV | Vitamin D3 receptor A | / | 0.464 | |
| 1m13 | HYF | Nuclear receptor subfamily 1 group I member 2 | / | 0.463 | |
| 3inv | C50 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.462 | |
| 1dss | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.461 | |
| 1pkf | EPD | Epothilone C/D epoxidase | 1.14 | 0.461 | |
| 3vt5 | YI2 | Vitamin D3 receptor | / | 0.461 | |
| 3zuy | TCH | Transporter | / | 0.460 | |
| 1tv8 | SAM | GTP 3',8-cyclase | 4.1.99.18 | 0.459 | |
| 2eau | CZA | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.459 | |
| 2hcd | BIV | Vitamin D3 receptor A | / | 0.459 | |
| 3nj0 | PYV | Abscisic acid receptor PYL2 | / | 0.459 | |
| 4g1z | 0VP | Vitamin D3 receptor A | / | 0.459 | |
| 1ouy | 094 | Mitogen-activated protein kinase 14 | / | 0.458 | |
| 2hb7 | O1C | Vitamin D3 receptor | / | 0.458 | |
| 2xa4 | AZ5 | Tyrosine-protein kinase JAK2 | / | 0.458 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.458 | |
| 1qbg | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.457 | |
| 1wbp | ADP | SRSF protein kinase 1 | 2.7.11.1 | 0.457 | |
| 2ktd | PUC | Prostaglandin-H2 D-isomerase | 5.3.99.2 | 0.457 | |
| 3qlx | QLR | Uncharacterized protein | / | 0.457 | |
| 4h98 | 14Q | Uncharacterized protein | / | 0.457 | |
| 4l42 | 5FI | Ribosomal protein S6 kinase beta-1 | 2.7.11.1 | 0.457 | |
| 1u3d | FAD | Cryptochrome-1 | / | 0.456 | |
| 2y1o | T26 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.456 | |
| 2y60 | M8F | Isopenicillin N synthase | 1.21.3.1 | 0.456 | |
| 3cyl | VIT | Basic phospholipase A2 homolog piratoxin-2 | / | 0.456 | |
| 3wec | AUI | Cytochrome P450 | / | 0.456 | |
| 1og5 | SWF | Cytochrome P450 2C9 | / | 0.455 | |
| 2has | C3O | Vitamin D3 receptor | / | 0.455 | |
| 2ph5 | NAD | Homospermidine synthase | / | 0.455 | |
| 3a4o | STU | Tyrosine-protein kinase Lyn | 2.7.10.2 | 0.455 | |
| 1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.454 | |
| 3nrr | D16 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.454 | |
| 3oew | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.454 | |
| 3qaq | QAQ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.454 | |
| 3th8 | TH9 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.454 | |
| 2drc | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 2nv6 | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.453 | |
| 2uxp | CLM | HTH-type transcriptional regulator TtgR | / | 0.453 | |
| 1bvr | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.452 | |
| 2pr2 | DG1 | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.452 | |
| 2rkv | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.452 | |
| 3gph | OID | Cytochrome P450 2E1 | 1.14.13 | 0.452 | |
| 4dre | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.452 | |
| 4ewn | 0VR | Imidazole glycerol phosphate synthase subunit HisF | 4.1.3 | 0.452 | |
| 1u3c | FAD | Cryptochrome-1 | / | 0.451 | |
| 1zmd | NAI | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.451 | |
| 2jcv | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | / | 0.451 | |
| 3ii4 | 3II | Dihydrolipoyl dehydrogenase | 1.8.1.4 | 0.451 | |
| 1d4a | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.450 | |
| 1eny | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.450 | |
| 1fmj | RTL | Retinol dehydratase | / | 0.450 | |
| 1kbo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.450 | |
| 3bc3 | OPT | Cathepsin L1 | 3.4.22.15 | 0.450 | |
| 3och | 2MX | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 4qmn | DB8 | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.450 | |
| 4ylf | FAD | Dihydroorotate dehydrogenase B (NAD(+)), electron transfer subunit homolog | / | 0.450 | |
| 1k6c | MK1 | Gag-Pol polyprotein | 3.4.23.16 | 0.449 | |
| 1nhz | 486 | Glucocorticoid receptor | / | 0.449 | |
| 1q5d | EPB | Epothilone C/D epoxidase | 1.14 | 0.449 | |
| 2aq8 | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.449 | |
| 3h8b | NSY | Cathepsin L1 | 3.4.22.15 | 0.449 | |
| 3opd | HIE | Heat shock protein 83 | / | 0.449 | |
| 3r7i | X9I | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.449 | |
| 3r7u | X96 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.449 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.449 | |
| 4ejg | NCT | Cytochrome P450 2A13 | 1.14.14.1 | 0.449 | |
| 4ia1 | BIV | Vitamin D3 receptor A | / | 0.449 | |
| 4j1r | I5R | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.449 | |
| 4xiw | AZM | Carbonic anhydrase, alpha type | / | 0.449 | |
| 2iod | MYC | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.448 | |
| 3fco | IIG | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.448 | |
| 3iqz | H4M | F420-dependent methylenetetrahydromethanopterin dehydrogenase | 1.5.98.1 | 0.448 | |
| 4anx | 534 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.448 | |
| 4ia2 | BIV | Vitamin D3 receptor A | / | 0.448 | |
| 1bvr | THT | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.447 | |
| 1k6t | XN1 | Gag-Pol polyprotein | 3.4.23.16 | 0.447 | |
| 2i40 | BLZ | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.447 | |
| 2itq | ITQ | Epidermal growth factor receptor | 2.7.10.1 | 0.447 | |
| 2izr | BRK | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.447 | |
| 3eel | 53T | Uncharacterized protein | / | 0.447 | |
| 3fp0 | FP0 | 15-O-acetyltransferase | / | 0.447 | |
| 3ibq | ATP | Pyridoxal kinase | / | 0.447 | |
| 3r7y | Z04 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.447 | |
| 3zk5 | Z18 | Cytochrome P450 monooxygenase PikC | / | 0.447 | |
| 4nmb | FAD | Bifunctional protein PutA | / | 0.447 | |
| 5a4k | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.447 | |
| 1dnp | FAD | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.446 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.446 | |
| 3v1y | NAD | Glyceraldehyde-3-phosphate dehydrogenase 1, cytosolic | 1.2.1.12 | 0.446 | |
| 3w5r | LOA | Vitamin D3 receptor | / | 0.446 | |
| 4lxh | C1E | Alpha/beta hydrolase fold | / | 0.446 | |
| 4ly9 | 1YY | Glucokinase regulatory protein | / | 0.446 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.445 | |
| 1dyh | DZF | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 1m8h | 6NI | Nitric oxide synthase, inducible | 1.14.13.39 | 0.445 | |
| 1w2x | RCP | Acetyl-CoA carboxylase | / | 0.445 | |
| 2cig | 1DG | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 2ovh | AS0 | Progesterone receptor | / | 0.445 | |
| 3d0b | SNX | Heat shock protein HSP 90-alpha | / | 0.445 | |
| 3kb0 | A8S | Abscisic acid receptor PYL2 | / | 0.445 | |
| 3le6 | 2BZ | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.445 | |
| 4gyz | D5M | Tyrosyl-DNA phosphodiesterase 2 | 3.1.4 | 0.445 | |
| 4i8v | BHF | Cytochrome P450 1A1 | 1.14.14.1 | 0.445 | |
| 4j6b | PLO | Cytochrome P450 monooxygenase | / | 0.445 | |
| 4lxj | LAN | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.445 | |
| 4nc3 | ERM | 5-hydroxytryptamine receptor 2B | / | 0.445 | |
| 4o4e | ATP | Kinase | / | 0.445 | |
| 5cpb | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.445 | |
| 1yon | A2R | 2-dehydropantoate 2-reductase | 1.1.1.169 | 0.444 | |
| 2npn | SAM | Putative cobalamin synthesis related protein | / | 0.444 | |
| 3a14 | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | / | 0.444 | |
| 3anm | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | 1.1.1.267 | 0.444 | |
| 3ey9 | TDP | Pyruvate dehydrogenase [ubiquinone] | 1.2.5.1 | 0.444 | |
| 3flw | FLW | Mitogen-activated protein kinase 14 | / | 0.444 | |
| 3ggg | NAD | Prephenate dehydrogenase | / | 0.444 | |
| 3lu8 | IQX | Serum albumin | / | 0.444 | |
| 3nux | 3NV | Cyclin-dependent kinase 6 | 2.7.11.22 | 0.444 | |
| 3qfx | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.444 | |
| 3tda | PN0 | Cytochrome P450 2D6 | / | 0.444 | |
| 4czt | CPS | CBL-interacting serine/threonine-protein kinase 23 | 2.7.11.1 | 0.444 | |
| 4fjy | FJY | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.444 | |
| 4g1d | 0VK | Vitamin D3 receptor A | / | 0.444 | |
| 4g7g | VFV | Lanosterol 14-alpha-demethylase | / | 0.444 | |
| 4h95 | 06U | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 4ruo | BIV | Vitamin D3 receptor A | / | 0.444 | |
| 1bl6 | SB6 | Mitogen-activated protein kinase 14 | / | 0.443 | |
| 1cd2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 1v1k | 3FP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.443 | |
| 1zmc | NAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.443 | |
| 2e9c | B75 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.443 | |
| 3bhe | BZN | Gag-Pol polyprotein | 3.4.23.16 | 0.443 | |
| 3kf7 | L9G | Mitogen-activated protein kinase 14 | / | 0.443 | |
| 3ml8 | ML8 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.443 | |
| 3otq | MZL | Bifunctional epoxide hydrolase 2 | 3.3.2.10 | 0.443 | |
| 4cd2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 4dfr | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 4fuy | EK2 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.443 | |
| 4gg7 | 0J8 | Hepatocyte growth factor receptor | 2.7.10.1 | 0.443 | |
| 1me7 | MOA | Inosine-5'-monophosphate dehydrogenase | / | 0.442 | |
| 1nhh | ANP | DNA mismatch repair protein MutL | / | 0.442 | |
| 1nuu | NAD | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.442 | |
| 1uy7 | PU4 | Heat shock protein HSP 90-alpha | / | 0.442 | |
| 2chw | 039 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.442 | |
| 2zaz | GK1 | Mitogen-activated protein kinase 14 | / | 0.442 | |
| 3mqe | 416 | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.442 | |
| 3o8t | BMU | Mitogen-activated protein kinase 14 | / | 0.442 | |
| 3qlz | QLZ | Uncharacterized protein | / | 0.442 | |
| 4cdm | FAD | Deoxyribodipyrimidine photolyase | / | 0.442 | |
| 5c8y | ACP | Tubulin tyrosine ligase | / | 0.442 | |
| 1sus | SAH | Caffeoyl-CoA O-methyltransferase | 2.1.1.104 | 0.441 | |
| 1u54 | ACP | Activated CDC42 kinase 1 | / | 0.441 | |
| 2y4g | TIR | TamL | / | 0.441 | |
| 2z3u | CRR | Cytochrome P450 | / | 0.441 | |
| 3i4b | Z48 | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.441 | |
| 3kpz | ZNE | Vitamin D3 receptor | / | 0.441 | |
| 3nxu | RIT | Cytochrome P450 3A4 | / | 0.441 | |
| 3of2 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.441 | |
| 4b7s | QLE | Cytochrome P450 monooxygenase PikC | / | 0.441 | |
| 4dti | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.441 | |
| 4gki | 0JN | Aminoglycoside 3'-phosphotransferase AphA1-IAB | / | 0.441 | |
| 4xli | 1N1 | Abelson tyrosine-protein kinase 2 | 2.7.10.2 | 0.441 | |
| 1e6e | FAD | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.440 | |
| 1nzf | UPG | DNA beta-glucosyltransferase | / | 0.440 | |
| 1q99 | ANP | Serine/threonine-protein kinase SKY1 | 2.7.11.1 | 0.440 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.440 | |
| 2b5v | NAP | Glucose 1-dehydrogenase | / | 0.440 | |
| 2xvd | AS6 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.440 | |
| 3c0g | 3AM | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.440 | |
| 3ezr | EZR | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 | |
| 3sgv | 2BJ | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.440 | |
| 3ua5 | 06X | Cytochrome P450 2B6 | 1.14.13 | 0.440 | |
| 4dlj | 6RG | Mitogen-activated protein kinase 14 | / | 0.440 | |
| 4h3c | 0YZ | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.440 | |
| 4hnc | 0UT | Mandelate racemase | / | 0.440 | |
| 4i02 | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.440 | |
| 4ipw | 1G7 | Mycocyclosin synthase | 1.14.21.9 | 0.440 |