Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3biv | 11U | Prothrombin | 3.4.21.5 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 3biv | 11U | Prothrombin | 3.4.21.5 | 1.000 | |
| 2znk | 31U | Prothrombin | 3.4.21.5 | 0.881 | |
| 2zi2 | 24U | Prothrombin | 3.4.21.5 | 0.856 | |
| 2zdv | 37U | Prothrombin | 3.4.21.5 | 0.852 | |
| 2zg0 | 50U | Prothrombin | 3.4.21.5 | 0.841 | |
| 2zda | 32U | Prothrombin | 3.4.21.5 | 0.838 | |
| 2zgx | 29U | Prothrombin | 3.4.21.5 | 0.813 | |
| 3biu | 10U | Prothrombin | 3.4.21.5 | 0.803 | |
| 2zc9 | 22U | Prothrombin | 3.4.21.5 | 0.791 | |
| 2ziq | 26U | Prothrombin | 3.4.21.5 | 0.790 | |
| 2zhf | 49U | Prothrombin | 3.4.21.5 | 0.784 | |
| 2zfq | 45U | Prothrombin | 3.4.21.5 | 0.781 | |
| 2zff | 53U | Prothrombin | 3.4.21.5 | 0.777 | |
| 2zhe | 13U | Prothrombin | 3.4.21.5 | 0.751 | |
| 3dhk | 23U | Prothrombin | 3.4.21.5 | 0.750 | |
| 4ax9 | N5N | Prothrombin | 3.4.21.5 | 0.744 | |
| 7kme | ACE_0BN_CHG_PRR | Prothrombin | 3.4.21.5 | 0.735 | |
| 3dux | 64U | Prothrombin | 3.4.21.5 | 0.721 | |
| 3eq0 | 2TS | Prothrombin | 3.4.21.5 | 0.721 | |
| 2zhq | 27U | Prothrombin | 3.4.21.5 | 0.718 | |
| 2zgb | 21U | Prothrombin | 3.4.21.5 | 0.706 | |
| 4bam | MM9 | Prothrombin | 3.4.21.5 | 0.694 | |
| 3hat | GLY_VAL_ARG_RNG | Prothrombin | 3.4.21.5 | 0.680 | |
| 1ypg | UIR | Prothrombin | 3.4.21.5 | 0.679 | |
| 1mue | CDD | Prothrombin | 3.4.21.5 | 0.676 | |
| 1d6w | 00R | Prothrombin | 3.4.21.5 | 0.668 | |
| 2zf0 | 51U | Prothrombin | 3.4.21.5 | 0.667 | |
| 2zfp | 19U | Prothrombin | 3.4.21.5 | 0.664 | |
| 2r2m | I50 | Prothrombin | 3.4.21.5 | 0.655 | |
| 3f68 | 91U | Prothrombin | 3.4.21.5 | 0.655 | |
| 1zrb | 062 | Prothrombin | 3.4.21.5 | 0.654 | |
| 1ypk | CCR | Prothrombin | 3.4.21.5 | 0.648 | |
| 2jh5 | 895 | Prothrombin | 3.4.21.5 | 0.647 | |
| 1d4p | BPP | Prothrombin | 3.4.21.5 | 0.645 | |
| 1k21 | IGN | Prothrombin | 3.4.21.5 | 0.642 | |
| 3egk | M18 | Prothrombin | 3.4.21.5 | 0.642 | |
| 4bak | M67 | Prothrombin | 3.4.21.5 | 0.642 | |
| 1afe | ALZ | Prothrombin | 3.4.21.5 | 0.640 | |
| 2anm | CDO | Prothrombin | 3.4.21.5 | 0.640 | |
| 1ta6 | 177 | Prothrombin | 3.4.21.5 | 0.639 | |
| 2bvs | 2CE | Prothrombin | 3.4.21.5 | 0.636 | |
| 1o0d | 163 | Prothrombin | 3.4.21.5 | 0.632 | |
| 3qwc | 98P | Prothrombin | 3.4.21.5 | 0.632 | |
| 1ae8 | AZL | Prothrombin | 3.4.21.5 | 0.630 | |
| 1t4u | 81A | Prothrombin | 3.4.21.5 | 0.628 | |
| 2v3o | I26 | Prothrombin | 3.4.21.5 | 0.628 | |
| 1z71 | L17 | Prothrombin | 3.4.21.5 | 0.626 | |
| 1mu8 | CDB | Prothrombin | 3.4.21.5 | 0.624 | |
| 1ype | UIP | Prothrombin | 3.4.21.5 | 0.624 | |
| 3c1k | T15 | Prothrombin | 3.4.21.5 | 0.623 | |
| 1c4u | IH1 | Prothrombin | 3.4.21.5 | 0.620 | |
| 1sb1 | 165 | Prothrombin | 3.4.21.5 | 0.620 | |
| 1ta2 | 176 | Prothrombin | 3.4.21.5 | 0.617 | |
| 4lxb | 7R9 | Prothrombin | 3.4.21.5 | 0.615 | |
| 1xm1 | GAH | Prothrombin | 3.4.21.5 | 0.614 | |
| 3qto | 10P | Prothrombin | 3.4.21.5 | 0.611 | |
| 1mu6 | CDA | Prothrombin | 3.4.21.5 | 0.610 | |
| 1ypj | UIB | Prothrombin | 3.4.21.5 | 0.610 | |
| 2zhw | 12U | Prothrombin | 3.4.21.5 | 0.607 | |
| 4baq | M4Z | Prothrombin | 3.4.21.5 | 0.607 | |
| 1d3d | BZT | Prothrombin | 3.4.21.5 | 0.606 | |
| 3p17 | 99P | Prothrombin | 3.4.21.5 | 0.602 | |
| 2jh0 | 701 | Prothrombin | 3.4.21.5 | 0.601 | |
| 1d9i | 00P | Prothrombin | 3.4.21.5 | 0.597 | |
| 3c27 | DKK | Prothrombin | 3.4.21.5 | 0.596 | |
| 1jwt | BLI | Prothrombin | 3.4.21.5 | 0.594 | |
| 1ypm | RA4 | Prothrombin | 3.4.21.5 | 0.594 | |
| 2gde | SN3 | Prothrombin | 3.4.21.5 | 0.586 | |
| 1vzq | SHY | Prothrombin | 3.4.21.5 | 0.583 | |
| 4ayy | 9MX | Prothrombin | 3.4.21.5 | 0.579 | |
| 4bah | MEL | Prothrombin | 3.4.21.5 | 0.579 | |
| 3utu | 1TS | Prothrombin | 3.4.21.5 | 0.578 | |
| 2cf9 | 348 | Prothrombin | 3.4.21.5 | 0.577 | |
| 1ny2 | ARG_PRO_PRO_GLY | Prothrombin | 3.4.21.5 | 0.576 | |
| 1oyt | FSN | Prothrombin | 3.4.21.5 | 0.575 | |
| 4hfp | 15U | Prothrombin | 3.4.21.5 | 0.572 | |
| 2bdy | UNB | Prothrombin | 3.4.21.5 | 0.571 | |
| 1c4y | IH3 | Prothrombin | 3.4.21.5 | 0.569 | |
| 2cn0 | F25 | Prothrombin | 3.4.21.5 | 0.569 | |
| 2uuj | 896 | Prothrombin | 3.4.21.5 | 0.569 | |
| 2a2x | NA9 | Prothrombin | 3.4.21.5 | 0.567 | |
| 2pks | G44 | Prothrombin | 3.4.21.5 | 0.567 | |
| 1uvs | I11 | Prothrombin | 3.4.21.5 | 0.566 | |
| 2v3h | I25 | Prothrombin | 3.4.21.5 | 0.566 | |
| 1nzq | 162 | Prothrombin | 3.4.21.5 | 0.565 | |
| 3qtv | 06P | Prothrombin | 3.4.21.5 | 0.565 | |
| 4n3l | 2FN | Prothrombin | 3.4.21.5 | 0.565 | |
| 1ghv | 120 | Prothrombin | 3.4.21.5 | 0.561 | |
| 1nm6 | L86 | Prothrombin | 3.4.21.5 | 0.560 | |
| 4bao | MVF | Prothrombin | 3.4.21.5 | 0.560 | |
| 2cf8 | ESH | Prothrombin | 3.4.21.5 | 0.559 | |
| 1c4v | IH2 | Prothrombin | 3.4.21.5 | 0.558 | |
| 4az2 | 9MU | Prothrombin | 3.4.21.5 | 0.557 | |
| 4e7r | 0NW | Prothrombin | 3.4.21.5 | 0.556 | |
| 4loy | 6XS | Prothrombin | 3.4.21.5 | 0.556 | |
| 1d3p | BT3 | Prothrombin | 3.4.21.5 | 0.554 | |
| 4rn6 | 15U | Prothrombin | 3.4.21.5 | 0.547 | |
| 1c5n | ESI | Prothrombin | 3.4.21.5 | 0.546 | |
| 1gj4 | 132 | Prothrombin | 3.4.21.5 | 0.539 | |
| 1k22 | MEL | Prothrombin | 3.4.21.5 | 0.538 | |
| 1gj5 | 130 | Prothrombin | 3.4.21.5 | 0.537 | |
| 2bxt | C2D | Prothrombin | 3.4.21.5 | 0.532 | |
| 1kts | C24 | Prothrombin | 3.4.21.5 | 0.528 | |
| 1bcu | PRL | Prothrombin | 3.4.21.5 | 0.523 | |
| 1ypl | RA8 | Prothrombin | 3.4.21.5 | 0.522 | |
| 1a4w | QWE | Prothrombin | 3.4.21.5 | 0.519 | |
| 1w7g | MIU | Prothrombin | 3.4.21.5 | 0.516 | |
| 4ayv | 9MQ | Prothrombin | 3.4.21.5 | 0.514 | |
| 1o2g | 696 | Prothrombin | 3.4.21.5 | 0.513 | |
| 4b1j | A1R | Poly(ADP-ribose) glycohydrolase | 3.2.1.143 | 0.509 | |
| 5irn | ADP | Nucleotide binding oligomerization domain containing 2 | / | 0.498 | |
| 1riw | OSC | Prothrombin | 3.4.21.5 | 0.496 | |
| 1o5g | CR9 | Prothrombin | 3.4.21.5 | 0.491 | |
| 2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.489 | |
| 2qim | ZEA | Class 10 plant pathogenesis-related protein | / | 0.489 | |
| 1zsk | 421 | Coagulation factor XI | 3.4.21.27 | 0.487 | |
| 5cmx | 0G6 | Prothrombin | 3.4.21.5 | 0.487 | |
| 1wqv | PSM | Coagulation factor VII | 3.4.21.21 | 0.485 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.480 | |
| 2zp0 | PI0 | Coagulation factor VII | 3.4.21.21 | 0.477 | |
| 1b2l | NDC | Alcohol dehydrogenase | 1.1.1.1 | 0.474 | |
| 1c1u | BAI | Prothrombin | 3.4.21.5 | 0.474 | |
| 2cv2 | GSU | Glutamate--tRNA ligase | 6.1.1.17 | 0.474 | |
| 2g24 | 7IG | Renin | 3.4.23.15 | 0.472 | |
| 3g0y | P9A | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.472 | |
| 3g5q | FAD | Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO | / | 0.472 | |
| 3jsx | CC2 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.471 | |
| 3qdz | PRO_ALA_PRO_ARG | Prothrombin | 3.4.21.5 | 0.471 | |
| 1ndh | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.470 | |
| 1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.470 | |
| 2j83 | BAT | Ulilysin | 3.4.24 | 0.470 | |
| 4fuf | 8UP | Urokinase-type plasminogen activator | 3.4.21.73 | 0.470 | |
| 2nr4 | FMN | Conserved protein | / | 0.468 | |
| 4fue | 7UP | Urokinase-type plasminogen activator | 3.4.21.73 | 0.468 | |
| 4na4 | A1R | Poly(ADP-ribose) glycohydrolase | 3.2.1.143 | 0.467 | |
| 3ehe | NAD | UDP-glucose 4-epimerase (GalE-1) | / | 0.465 | |
| 5f8f | SFG | Possible transcriptional regulatory protein | / | 0.465 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.464 | |
| 2ddo | ATP | Pyridoxine/pyridoxal/pyridoxamine kinase | / | 0.464 | |
| 2pg0 | FAD | Acyl-CoA dehydrogenase | / | 0.464 | |
| 2rlc | CHD | Choloylglycine hydrolase | 3.5.1.24 | 0.463 | |
| 3k3h | BYE | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.463 | |
| 4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.463 | |
| 4d03 | NAP | Phenylacetone monooxygenase | 1.14.13.92 | 0.463 | |
| 4i4z | 2NE | 1,4-dihydroxy-2-naphthoyl-CoA synthase | / | 0.463 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.463 | |
| 2y60 | M8F | Isopenicillin N synthase | 1.21.3.1 | 0.462 | |
| 4lzw | THM | Uridine phosphorylase | / | 0.462 | |
| 5eja | TD6 | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.462 | |
| 1hb3 | SCV | Isopenicillin N synthase | 1.21.3.1 | 0.461 | |
| 1hku | NAD | C-terminal-binding protein 1 | 1.1.1 | 0.461 | |
| 2xb9 | XNW | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.461 | |
| 2xuo | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.461 | |
| 4m0f | 1YK | Acetylcholinesterase | 3.1.1.7 | 0.461 | |
| 1c1w | BAH | Prothrombin | 3.4.21.5 | 0.460 | |
| 3fhx | PXL | Pyridoxal kinase | 2.7.1.35 | 0.460 | |
| 3fpd | SAH | Histone-lysine N-methyltransferase EHMT1 | / | 0.460 | |
| 3oaf | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.460 | |
| 4a86 | 2AN | Major pollen allergen Bet v 1-A | / | 0.460 | |
| 4mlp | 2CX | Cryptochrome-2 | / | 0.460 | |
| 4yjd | FAD | D-amino-acid oxidase | 1.4.3.3 | 0.460 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.459 | |
| 4f1l | 0RY | Poly [ADP-ribose] polymerase 14 | 2.4.2.30 | 0.459 | |
| 4g2j | 0WF | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.459 | |
| 4zzi | 1NS | NAD-dependent protein deacetylase sirtuin-1 | 3.5.1 | 0.459 | |
| 1rt9 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.458 | |
| 2g00 | 4QC | Coagulation factor X | 3.4.21.6 | 0.458 | |
| 3gjw | GJW | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.458 | |
| 3n3z | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.458 | |
| 3ozd | 4CT | S-methyl-5'-thioadenosine phosphorylase | / | 0.458 | |
| 3vn2 | TLS | Peroxisome proliferator-activated receptor gamma | / | 0.458 | |
| 2gv8 | NDP | Thiol-specific monooxygenase | 1.14.13 | 0.457 | |
| 3mo0 | SAH | Histone-lysine N-methyltransferase EHMT1 | / | 0.457 | |
| 3swc | SAH | Histone-lysine N-methyltransferase EHMT1 | / | 0.457 | |
| 1f20 | FAD | Nitric oxide synthase, brain | 1.14.13.39 | 0.456 | |
| 2aba | STR | Pentaerythritol tetranitrate reductase | / | 0.456 | |
| 2hxz | H7J | Cathepsin S | 3.4.22.27 | 0.456 | |
| 3ic9 | FAD | Putative dihydrolipoamide dehydrogenase | / | 0.456 | |
| 3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.456 | |
| 3s7d | LEU_SER_LYS_LYS_MLZ | N-lysine methyltransferase SMYD2 | / | 0.456 | |
| 3wqm | B29 | Diterpene synthase | 3.1.7.8 | 0.456 | |
| 4ejm | NAP | Putative zinc-binding dehydrogenase | / | 0.456 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.455 | |
| 4cf6 | CBD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.455 | |
| 4ey6 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.455 | |
| 4g95 | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 1pqc | 444 | Oxysterols receptor LXR-beta | / | 0.454 | |
| 1rkw | PNT | HTH-type transcriptional regulator QacR | / | 0.454 | |
| 1rr6 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.454 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.454 | |
| 2p2m | PRX | Acetyl-coenzyme A synthetase | / | 0.454 | |
| 2yy2 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.454 | |
| 3ai0 | PNW | Beta-glucosidase | / | 0.454 | |
| 1owe | 675 | Urokinase-type plasminogen activator | 3.4.21.73 | 0.453 | |
| 2c4f | GIL | Coagulation factor VII | 3.4.21.21 | 0.453 | |
| 2dxd | ANP | Nucleoside diphosphate kinase | 2.7.4.6 | 0.453 | |
| 2j14 | GNI | Peroxisome proliferator-activated receptor delta | / | 0.453 | |
| 2nq8 | ZID | Enoyl-ACP reductase | / | 0.453 | |
| 2uag | UMA | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.453 | |
| 2y6f | M9F | Isopenicillin N synthase | 1.21.3.1 | 0.453 | |
| 3g70 | A5T | Renin | 3.4.23.15 | 0.453 | |
| 3hu1 | AGS | Transitional endoplasmic reticulum ATPase | 3.6.4.6 | 0.453 | |
| 3wag | TYD | Glycosyltransferase | / | 0.453 | |
| 4m5p | FMN | NADPH dehydrogenase | / | 0.453 | |
| 4xbj | IN5 | Alanine racemase, biosynthetic | / | 0.453 | |
| 5eb5 | FAD | (R)-mandelonitrile lyase 1 | 4.1.2.10 | 0.453 | |
| 1sl3 | 170 | Prothrombin | 3.4.21.5 | 0.452 | |
| 2h21 | SAM | Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplastic | 2.1.1.127 | 0.452 | |
| 2q1s | NAI | Putative nucleotide sugar epimerase/ dehydratase | / | 0.452 | |
| 3k1w | BFX | Renin | 3.4.23.15 | 0.452 | |
| 3sp9 | IL2 | Peroxisome proliferator-activated receptor delta | / | 0.452 | |
| 4y1b | NAP | AntE | / | 0.452 | |
| 1kbo | 340 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.451 | |
| 1owk | 303 | Urokinase-type plasminogen activator | 3.4.21.73 | 0.451 | |
| 1p0h | COA | Mycothiol acetyltransferase | 2.3.1.189 | 0.451 | |
| 2aq7 | TL5 | 3-oxoacyl-[acyl-carrier-protein] synthase 1 | 2.3.1.41 | 0.451 | |
| 2vf3 | GVS | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.451 | |
| 3elb | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.451 | |
| 3h3q | H13 | Collagen type IV alpha-3-binding protein | / | 0.451 | |
| 3v4a | PK1 | Androgen receptor | / | 0.451 | |
| 2bu9 | HFV | Isopenicillin N synthase | 1.21.3.1 | 0.450 | |
| 3fp0 | FP0 | 15-O-acetyltransferase | / | 0.450 | |
| 3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.450 | |
| 3pm1 | ET | HTH-type transcriptional regulator QacR | / | 0.450 | |
| 3vil | SA0 | Beta-glucosidase | / | 0.450 | |
| 4b1r | ITC | Tetracycline repressor protein class D | / | 0.450 | |
| 1khe | GCP | Phosphoenolpyruvate carboxykinase, cytosolic [GTP] | 4.1.1.32 | 0.449 | |
| 1ma0 | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.449 | |
| 1okl | MNS | Carbonic anhydrase 2 | 4.2.1.1 | 0.449 | |
| 1q84 | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.449 | |
| 2g8y | NAD | Hydroxycarboxylate dehydrogenase B | / | 0.449 | |
| 2qf2 | GDP | Phosphoenolpyruvate carboxykinase, cytosolic [GTP] | 4.1.1.32 | 0.449 | |
| 2xug | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.449 | |
| 3e2s | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.449 | |
| 4fui | UI3 | Urokinase-type plasminogen activator | 3.4.21.73 | 0.449 | |
| 4gv4 | MEJ | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.449 | |
| 5ej9 | TPP | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.449 | |
| 5jhn | SAM | Histone-lysine N-methyltransferase EHMT2 | / | 0.449 | |
| 1icv | FMN | Oxygen-insensitive NAD(P)H nitroreductase | / | 0.448 | |
| 3c36 | KAI | Glutamate receptor ionotropic, kainate 1 | / | 0.448 | |
| 3o0i | P54 | Heat shock protein HSP 90-alpha | / | 0.448 | |
| 3po6 | DT9 | Carbonic anhydrase 2 | 4.2.1.1 | 0.448 | |
| 5hs1 | VOR | Lanosterol 14-alpha demethylase | / | 0.448 | |
| 1khb | GCP | Phosphoenolpyruvate carboxykinase, cytosolic [GTP] | 4.1.1.32 | 0.447 | |
| 1nhk | CMP | Nucleoside diphosphate kinase | 2.7.4.6 | 0.447 | |
| 1rz1 | NAD | Phenol 2-hydroxylase component B | / | 0.447 | |
| 1rzu | ADP | Glycogen synthase 1 | 2.4.1.21 | 0.447 | |
| 3wav | DWV | Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 | 3.1.4.39 | 0.447 | |
| 4a87 | NAR | Major pollen allergen Bet v 1-A | / | 0.447 | |
| 4eb7 | PLP | Cysteine desulfurase IscS 2 | / | 0.447 | |
| 4gv2 | 5ME | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.447 | |
| 4n82 | FMN | Ribonucleotide reductase (NrdI family protein), putative | / | 0.447 | |
| 4uug | PXG | Branched-chain amino acid aminotransferase, putative | / | 0.447 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.446 | |
| 1i5r | HYC | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.446 | |
| 1ju2 | FAD | (R)-mandelonitrile lyase 2 | 4.1.2.10 | 0.446 | |
| 1tsx | UMP | Thymidylate synthase | / | 0.446 | |
| 1uym | PU3 | Heat shock protein HSP 90-beta | / | 0.446 | |
| 1vbi | NAD | Malate/L-lactate dehydrogenase family protein | / | 0.446 | |
| 1zis | INI | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.446 | |
| 2fe4 | GDP | Ras-related protein Rab-6B | / | 0.446 | |
| 2fw3 | BUI | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.446 | |
| 2v2z | CDM | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.446 | |
| 2vyq | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.446 | |
| 2ym1 | NAP | Phenylacetone monooxygenase | 1.14.13.92 | 0.446 | |
| 3dyl | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.446 | |
| 3qvi | K95 | HAP protein | / | 0.446 | |
| 4alx | IZN | Acetylcholine-binding protein | / | 0.446 | |
| 5f54 | TMP | Single-stranded-DNA-specific exonuclease | / | 0.446 | |
| 1cul | FOK | Adenylate cyclase type 2 | / | 0.445 | |
| 1cul | FOK | Adenylate cyclase type 5 | / | 0.445 | |
| 1x1r | GDP | Ras-related protein M-Ras | / | 0.445 | |
| 2bsx | NOS | Purine nucleoside phosphorylase | / | 0.445 | |
| 2xui | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.445 | |
| 2xuj | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.445 | |
| 2y5h | Y5H | Coagulation factor X | 3.4.21.6 | 0.445 | |
| 2zsh | GA3 | Gibberellin receptor GID1A | 3 | 0.445 | |
| 3gwf | NAP | Cyclohexanone monooxygenase | / | 0.445 | |
| 3h4v | NAP | Pteridine reductase 1 | 1.5.1.33 | 0.445 | |
| 3hl0 | NAD | Maleylacetate reductase | / | 0.445 | |
| 3ho9 | N3A | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.445 | |
| 3phi | NDP | Shikimate dehydrogenase (NADP(+)) | / | 0.445 | |
| 3vev | 0H4 | Glucokinase | 2.7.1.2 | 0.445 | |
| 4bek | XK0 | Beta-secretase 1 | 3.4.23.46 | 0.445 | |
| 4kos | 4KO | Uncharacterized protein | / | 0.445 | |
| 4ms1 | 381 | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.445 | |
| 4nie | NBH | Nuclear receptor ROR-gamma | / | 0.445 | |
| 4xbf | FAD | Lysine-specific histone demethylase 1A | 1 | 0.445 | |
| 1nyx | DRF | Peroxisome proliferator-activated receptor gamma | / | 0.444 | |
| 1ozv | SAH | Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplastic | 2.1.1.127 | 0.444 | |
| 2g1s | 4IG | Renin | 3.4.23.15 | 0.444 | |
| 2ptf | FMN | Uncharacterized protein MTH_863 | / | 0.444 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.444 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.444 | |
| 4hhz | 15S | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.444 | |
| 4jln | 18V | Deoxycytidine kinase | 2.7.1.74 | 0.444 | |
| 4q0k | GA3 | Phytohormone-binding protein | / | 0.444 | |
| 5std | UNN | Scytalone dehydratase | 4.2.1.94 | 0.444 | |
| 1rsz | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.443 | |
| 1rxj | BNI | Streptavidin | / | 0.443 | |
| 1wli | FMN | FMN-binding protein | / | 0.443 | |
| 3zho | FMN | NAD(P)H dehydrogenase (quinone) | / | 0.443 | |
| 4b1e | 6T6 | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 4g2r | H1L | Probable propionyl-CoA carboxylase beta chain 6 | 6.4.1.3 | 0.443 | |
| 4gh6 | LUO | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.443 | |
| 4i8v | BHF | Cytochrome P450 1A1 | 1.14.14.1 | 0.443 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
| 1fap | RAP | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.442 | |
| 1fap | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.442 | |
| 1o1t | 2NH | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.442 | |
| 1p0p | BCH | Cholinesterase | 3.1.1.8 | 0.442 | |
| 1w1w | AGS | Structural maintenance of chromosomes protein 1 | / | 0.442 | |
| 1zdw | FLV | Prenyltransferase | / | 0.442 | |
| 2c1z | U2F | Anthocyanidin 3-O-glucosyltransferase 2 | 2.4.1.115 | 0.442 | |
| 2pk3 | A2R | GDP-6-deoxy-D-mannose reductase | / | 0.442 | |
| 2psw | COA | N-alpha-acetyltransferase 50 | / | 0.442 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
| 2wu4 | HBP | Acetylcholinesterase | 3.1.1.7 | 0.442 | |
| 2ykj | YKJ | Heat shock protein HSP 90-alpha | / | 0.442 | |
| 2ylt | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.442 | |
| 3g11 | P9C | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.442 | |
| 3nsh | 957 | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 3uzw | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.442 | |
| 4i0i | 957 | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 1nfy | RTR | Coagulation factor X | 3.4.21.6 | 0.441 | |
| 1pua | COA | HAT A1 | / | 0.441 | |
| 1qti | GNT | Acetylcholinesterase | 3.1.1.7 | 0.441 | |
| 1siq | FAD | Glutaryl-CoA dehydrogenase, mitochondrial | 1.3.8.6 | 0.441 | |
| 2cnd | FAD | Nitrate reductase [NADH] | 1.7.1.1 | 0.441 | |
| 2xvf | FAD | Putative flavin-containing monooxygenase | / | 0.441 | |
| 3ada | NAD | Subunit alpha of sarocosine oxidase | / | 0.441 | |
| 3b4f | TUO | Carbonic anhydrase 2 | 4.2.1.1 | 0.441 | |
| 3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.441 | |
| 3f3y | 4OA | Bile salt sulfotransferase | 2.8.2.14 | 0.441 | |
| 4bub | ADP | UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--LD-lysine ligase | / | 0.441 | |
| 4eqk | MGT | Polymerase basic protein 2 | / | 0.441 | |
| 4f4d | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.441 | |
| 4fub | 4UP | Urokinase-type plasminogen activator | 3.4.21.73 | 0.441 | |
| 4i42 | 1HA | 1,4-dihydroxy-2-naphthoyl-CoA synthase | / | 0.441 | |
| 4uth | FMN | Xenobiotic reductase | / | 0.441 | |
| 1c7o | PPG | Hemolysin | / | 0.440 | |
| 1lqd | CMI | Coagulation factor X | 3.4.21.6 | 0.440 | |
| 1uxk | NAD | Malate dehydrogenase | / | 0.440 | |
| 1x1c | SAH | C-20 methyltransferase | / | 0.440 | |
| 1zbd | GTP | Ras-related protein Rab-3A | / | 0.440 | |
| 2o1s | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.440 | |
| 2qw0 | 34Z | 4-chlorobenzoyl CoA ligase | / | 0.440 | |
| 2x96 | RX3 | Angiotensin-converting enzyme | 3.4.15.1 | 0.440 | |
| 2xlu | NA7 | Putative flavin-containing monooxygenase | / | 0.440 | |
| 2yq9 | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.440 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.440 | |
| 3jus | BCD | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.440 | |
| 3qgf | 46F | Genome polyprotein | 2.7.7.48 | 0.440 | |
| 3tg4 | SAM | N-lysine methyltransferase SMYD2 | / | 0.440 | |
| 3wv9 | FEG | Hmd co-occurring protein HcgE | / | 0.440 | |
| 4a95 | 9MT | Glycylpeptide N-tetradecanoyltransferase | / | 0.440 | |
| 4emd | C5P | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.440 | |
| 4j33 | FAD | Kynurenine 3-monooxygenase | / | 0.440 | |
| 4jtq | FLP | Aldo-keto reductase family 1 member C2 | / | 0.440 | |
| 4ozt | P1A | Ecdysone receptor, putative | / | 0.440 |