sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2wug | HPK | 4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase | 3.7.1.17 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 2wug | HPK | 4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase | 3.7.1.17 | 1.000 | |
| 2wuf | KEM | 4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase | 3.7.1.17 | 0.666 | |
| 2wue | KEK | 4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase | 3.7.1.17 | 0.640 | |
| 3vt7 | VDX | Vitamin D3 receptor | / | 0.501 | |
| 4jvb | 1M0 | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.496 | |
| 3r04 | UNQ | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.491 | |
| 4g1z | 0VP | Vitamin D3 receptor A | / | 0.491 | |
| 3vt6 | 5YI | Vitamin D3 receptor | / | 0.488 | |
| 1s19 | MC9 | Vitamin D3 receptor | / | 0.487 | |
| 3vtb | TKA | Vitamin D3 receptor | / | 0.487 | |
| 2jn3 | JN3 | Fatty acid-binding protein, liver | / | 0.486 | |
| 3tz3 | B36 | Acetyl-CoA carboxylase | / | 0.486 | |
| 3bac | 3B9 | DNA ligase | / | 0.485 | |
| 3vtd | TKD | Vitamin D3 receptor | / | 0.484 | |
| 3vtc | TK3 | Vitamin D3 receptor | / | 0.482 | |
| 3a78 | 3EV | Vitamin D3 receptor | / | 0.481 | |
| 1txi | TX5 | Vitamin D3 receptor | / | 0.480 | |
| 1osv | CHC | Bile acid receptor | / | 0.479 | |
| 4bb6 | HD1 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.478 | |
| 2w9s | TOP | Dihydrofolate reductase type 1 from Tn4003 | 1.5.1.3 | 0.475 | |
| 3tvu | B37 | Acetyl-CoA carboxylase | / | 0.475 | |
| 3vt5 | YI2 | Vitamin D3 receptor | / | 0.475 | |
| 1g4s | TPS | Thiamine-phosphate synthase | / | 0.474 | |
| 1jip | KTN | 6-deoxyerythronolide B hydroxylase | / | 0.474 | |
| 2hbh | XE4 | Vitamin D3 receptor A | / | 0.473 | |
| 2nq8 | ZID | Enoyl-ACP reductase | / | 0.473 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.473 | |
| 4cax | 646 | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.473 | |
| 2wey | EV1 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.472 | |
| 2ev9 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.471 | |
| 3w0g | W07 | Vitamin D3 receptor | / | 0.471 | |
| 4g1d | 0VK | Vitamin D3 receptor A | / | 0.471 | |
| 1ot7 | IU5 | Bile acid receptor | / | 0.470 | |
| 3w0h | W12 | Vitamin D3 receptor | / | 0.470 | |
| 1ppj | ANY | Cytochrome b | / | 0.469 | |
| 1xu9 | CPS | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.469 | |
| 2har | OCC | Vitamin D3 receptor | / | 0.469 | |
| 4nxu | ADP | Mitochondrial dynamics protein MID51 | / | 0.469 | |
| 2hcd | BIV | Vitamin D3 receptor A | / | 0.468 | |
| 2zlc | VDX | Vitamin D3 receptor | / | 0.468 | |
| 3fco | IIG | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.468 | |
| 3vt9 | YI4 | Vitamin D3 receptor | / | 0.468 | |
| 5eai | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.468 | |
| 1v35 | NAI | Enoyl-ACP reductase | / | 0.467 | |
| 3iae | D7K | Benzaldehyde lyase | / | 0.467 | |
| 3p3z | P3Z | Putative cytochrome P450 | / | 0.466 | |
| 3vrt | YS2 | Vitamin D3 receptor | / | 0.466 | |
| 4lxh | C1E | Alpha/beta hydrolase fold | / | 0.466 | |
| 4z24 | FAD | Putative GMC-type oxidoreductase R135 | 1 | 0.466 | |
| 4e5y | NDP | GDP-L-fucose synthase | 1.1.1.271 | 0.465 | |
| 5iqi | GNP | Bifunctional AAC/APH | 2.3.1 | 0.465 | |
| 5k2c | ZMA | Adenosine receptor A2a | / | 0.465 | |
| 1ot7 | CHC | Bile acid receptor | / | 0.464 | |
| 4rup | H97 | Vitamin D3 receptor A | / | 0.464 | |
| 1ie9 | VDX | Vitamin D3 receptor | / | 0.463 | |
| 1jio | DEB | 6-deoxyerythronolide B hydroxylase | / | 0.463 | |
| 3ml8 | ML8 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.463 | |
| 4bzo | 676 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.463 | |
| 1fml | RTL | Retinol dehydratase | / | 0.462 | |
| 1qbg | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.462 | |
| 2hb8 | MVD | Vitamin D3 receptor | / | 0.462 | |
| 3byz | H11 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.462 | |
| 4j6d | TES | Cytochrome P450 monooxygenase | / | 0.462 | |
| 4ruj | VDX | Vitamin D3 receptor A | / | 0.462 | |
| 1cf3 | FAD | Glucose oxidase | 1.1.3.4 | 0.461 | |
| 1xal | NAD | 3-dehydroquinate synthase | / | 0.461 | |
| 3u8h | BHP | Phospholipase A2, membrane associated | / | 0.461 | |
| 3vt8 | YI3 | Vitamin D3 receptor | / | 0.461 | |
| 4i6g | FAD | Cryptochrome-2 | / | 0.461 | |
| 4ixf | IXF | Dihydrofolate reductase | 1.5.1.3 | 0.461 | |
| 1ie8 | KH1 | Vitamin D3 receptor | / | 0.460 | |
| 1rk3 | VDX | Vitamin D3 receptor | / | 0.460 | |
| 2v1a | FMN | NPH1-1 | / | 0.460 | |
| 3cxw | 7CP | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.460 | |
| 3qk0 | QK0 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.460 | |
| 4g2h | 0VQ | Vitamin D3 receptor A | / | 0.460 | |
| 4itf | TFY | Vitamin D3 receptor | / | 0.460 | |
| 4j6b | PLO | Cytochrome P450 monooxygenase | / | 0.460 | |
| 4jv6 | 18F | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.460 | |
| 5a4k | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.460 | |
| 5jsc | FAD | Putative acyl-CoA dehydrogenase | / | 0.460 | |
| 3d3e | D3E | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.459 | |
| 3ssn | MVI | Mycinamicin VI 2''-O-methyltransferase | / | 0.459 | |
| 3vrw | YS5 | Vitamin D3 receptor | / | 0.459 | |
| 3w5p | 4OA | Vitamin D3 receptor | / | 0.459 | |
| 1d4a | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.458 | |
| 3qaq | QAQ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.458 | |
| 3qlr | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.458 | |
| 1db1 | VDX | Vitamin D3 receptor | / | 0.457 | |
| 1qax | HMG | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 1.1.1.88 | 0.457 | |
| 2a1t | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.457 | |
| 3w5r | LOA | Vitamin D3 receptor | / | 0.457 | |
| 4oxy | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.457 | |
| 1iyz | NDP | Probable quinone oxidoreductase | / | 0.456 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.456 | |
| 2o4r | VD5 | Vitamin D3 receptor | / | 0.456 | |
| 3kpz | ZNE | Vitamin D3 receptor | / | 0.456 | |
| 4enh | FVX | Cholesterol 24-hydroxylase | / | 0.456 | |
| 4ia2 | BIV | Vitamin D3 receptor A | / | 0.456 | |
| 4ite | TEY | Vitamin D3 receptor | / | 0.456 | |
| 4ly9 | 1YY | Glucokinase regulatory protein | / | 0.456 | |
| 4nkv | AER | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.456 | |
| 4rlh | 0WE | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.456 | |
| 1h69 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.455 | |
| 2hc4 | VDX | Vitamin D3 receptor A | / | 0.455 | |
| 2zl9 | VDA | Vitamin D3 receptor | / | 0.455 | |
| 3qwb | NDP | Probable quinone oxidoreductase | 1.6.5.5 | 0.455 | |
| 3vt4 | 5YI | Vitamin D3 receptor | / | 0.455 | |
| 4ork | GDP | Bifunctional AAC/APH | 2.3.1 | 0.455 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.455 | |
| 1byg | STU | Tyrosine-protein kinase CSK | / | 0.454 | |
| 2ieb | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.454 | |
| 2qo9 | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.454 | |
| 2y1o | T26 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.454 | |
| 2zla | VDB | Vitamin D3 receptor | / | 0.454 | |
| 3w0i | O11 | Vitamin D3 receptor | / | 0.454 | |
| 4bb5 | HD2 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.454 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.454 | |
| 4z63 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.454 | |
| 1fmj | RTL | Retinol dehydratase | / | 0.453 | |
| 1vrw | NAI | Enoyl-ACP reductase | / | 0.453 | |
| 3l08 | ZIG | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.453 | |
| 3r5y | F42 | Uncharacterized protein | / | 0.453 | |
| 3w0j | T08 | Vitamin D3 receptor | / | 0.453 | |
| 4ia3 | BIV | Vitamin D3 receptor A | / | 0.453 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.452 | |
| 1nyt | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.452 | |
| 1x8l | OXR | Retinol dehydratase | / | 0.452 | |
| 2qo5 | CHD | Fatty acid-binding protein 10-A, liver basic | / | 0.452 | |
| 3t2y | FAD | Sulfide-quinone reductase | / | 0.452 | |
| 3up3 | XCA | aceDAF-12 | / | 0.452 | |
| 4bii | PYW | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.452 | |
| 4o70 | 1QK | Bromodomain-containing protein 4 | / | 0.452 | |
| 1gal | FAD | Glucose oxidase | 1.1.3.4 | 0.451 | |
| 2aib | ERG | Beta-elicitin cinnamomin | / | 0.451 | |
| 2j2i | LY4 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.451 | |
| 2vtd | LKM | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.451 | |
| 3gmd | 2M3 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.451 | |
| 3h1j | SMA | Cytochrome b | / | 0.451 | |
| 3r6s | CMP | CRP-like cAMP-activated global transcriptional regulator | / | 0.451 | |
| 3t2z | FAD | Sulfide-quinone reductase | / | 0.451 | |
| 3vru | YS3 | Vitamin D3 receptor | / | 0.451 | |
| 3zbn | COA | 3-ketoacyl-CoA thiolase-like protein | / | 0.451 | |
| 4jvf | 17X | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.451 | |
| 1kbo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.450 | |
| 3bxx | QUE | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.450 | |
| 3pm9 | FAD | Putative oxidoreductase | / | 0.450 | |
| 4at0 | FAD | Possible succinate dehydrogenase | / | 0.450 | |
| 4fhi | 0S4 | Vitamin D3 receptor A | / | 0.450 | |
| 4gi2 | NAP | Crotonyl-CoA carboxylase/reductase | / | 0.450 | |
| 4m87 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.450 | |
| 1nvt | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.449 | |
| 2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.449 | |
| 2q66 | ATP | Poly(A) polymerase | 2.7.7.19 | 0.449 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.449 | |
| 2wyv | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.449 | |
| 2x86 | ADP | ADP-L-glycero-D-manno-heptose-6-epimerase | / | 0.449 | |
| 3mg3 | ECH | Orange carotenoid-binding protein | / | 0.449 | |
| 4ez8 | DHF | Thymidylate synthase | 2.1.1.45 | 0.449 | |
| 1p44 | GEQ | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.448 | |
| 2bdf | 24A | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.448 | |
| 2bik | BI1 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.448 | |
| 2dr3 | ADP | UPF0273 protein PH0284 | / | 0.448 | |
| 2q4w | FAD | Cytokinin dehydrogenase 7 | 1.5.99.12 | 0.448 | |
| 3cyl | VIT | Basic phospholipase A2 homolog piratoxin-2 | / | 0.448 | |
| 3oib | FDA | Putative acyl-CoA dehydrogenase | / | 0.448 | |
| 3r5z | F42 | Uncharacterized protein | / | 0.448 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.448 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.447 | |
| 1jut | LYD | Thymidylate synthase | / | 0.447 | |
| 1rx5 | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 1t9g | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.447 | |
| 2ham | C33 | Vitamin D3 receptor | / | 0.447 | |
| 2iod | MYC | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.447 | |
| 3cuk | FAD | D-amino-acid oxidase | 1.4.3.3 | 0.447 | |
| 3g5m | FAD | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.447 | |
| 3tda | PN0 | Cytochrome P450 2D6 | / | 0.447 | |
| 4g3j | VNT | Lanosterol 14-alpha-demethylase | / | 0.447 | |
| 3rey | XAC | Adenosine receptor A2a | / | 0.447 | |
| 2eba | FAD | Putative glutaryl-CoA dehydrogenase | / | 0.446 | |
| 2h2q | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.446 | |
| 2has | C3O | Vitamin D3 receptor | / | 0.446 | |
| 4at3 | LTI | BDNF/NT-3 growth factors receptor | 2.7.10.1 | 0.446 | |
| 4hfr | 14M | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.446 | |
| 4ure | 1PS | Cyclohexanol dehydrogenase | / | 0.446 | |
| 1gqt | ACP | Ribokinase | / | 0.445 | |
| 1qvn | FRI | Interleukin-2 | / | 0.445 | |
| 2pui | ADP | Methylthioribose kinase | 2.7.1.100 | 0.445 | |
| 3apf | BMW | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.445 | |
| 3drc | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 4bzn | UGX | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.445 | |
| 4feh | FAD | Decaprenylphosphoryl-beta-D-ribose oxidase | / | 0.445 | |
| 4kln | AGS | Transitional endoplasmic reticulum ATPase | 3.6.4.6 | 0.445 | |
| 4q72 | FAD | Bifunctional protein PutA | / | 0.445 | |
| 5k2a | ZMA | Adenosine receptor A2a | / | 0.445 | |
| 5jtb | ZMA | Adenosine receptor A2a | / | 0.445 | |
| 1h66 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.444 | |
| 2giv | ACO | Histone acetyltransferase KAT8 | / | 0.444 | |
| 2nn7 | M29 | Carbonic anhydrase 1 | 4.2.1.1 | 0.444 | |
| 2wpx | ACO | Orf14 | / | 0.444 | |
| 3gw9 | VNI | Lanosterol 14-alpha-demethylase | / | 0.444 | |
| 3p8i | FMN | Pentaerythritol tetranitrate reductase | / | 0.444 | |
| 3uag | UMA | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.444 | |
| 3uoz | NAP | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.444 | |
| 4dk5 | 0KO | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.444 | |
| 4icy | FAD | PgaE | / | 0.444 | |
| 5byl | GCP | Bifunctional AAC/APH | 2.3.1 | 0.444 | |
| 1syn | F89 | Thymidylate synthase | / | 0.443 | |
| 1szm | BI4 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.443 | |
| 2fr0 | NDP | 6-deoxyerythronolide-B synthase EryA1, modules 1 and 2 | / | 0.443 | |
| 3frd | DHF | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 3r7k | FDA | Probable acyl CoA dehydrogenase | / | 0.443 | |
| 3ruk | AER | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.443 | |
| 3sz0 | FAD | Sulfide-quinone reductase | / | 0.443 | |
| 3vrv | YSD | Vitamin D3 receptor | / | 0.443 | |
| 3w0c | 6DS | Vitamin D3 receptor | / | 0.443 | |
| 3zdn | FAD | Monoamine oxidase N | 1.4.3.4 | 0.443 | |
| 4g20 | 484 | Vitamin D3 receptor A | / | 0.443 | |
| 4nky | 3QZ | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.443 | |
| 1fp1 | HCC | Isoliquiritigenin 2'-O-methyltransferase | / | 0.442 | |
| 1gjr | NAP | Ferredoxin--NADP reductase | 1.18.1.2 | 0.442 | |
| 1rjk | VDZ | Vitamin D3 receptor | / | 0.442 | |
| 3bgx | MEF | Thymidylate synthase | / | 0.442 | |
| 3th8 | TH9 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.442 | |
| 3tnl | NAD | Shikimate dehydrogenase (NADP(+)) | / | 0.442 | |
| 4c3x | FAD | 3-ketosteroid dehydrogenase | / | 0.442 | |
| 4e37 | NDP | Catalase | 1.11.1.6 | 0.442 | |
| 4fhh | 0U3 | Vitamin D3 receptor A | / | 0.442 | |
| 4ubs | DIF | Pentalenic acid synthase | 1.14.15.11 | 0.442 | |
| 4wq4 | ATP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.442 | |
| 1dtp | APU | Diphtheria toxin | / | 0.441 | |
| 1dxo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.441 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.441 | |
| 1hnc | GDN | Glutathione S-transferase Mu 2 | 2.5.1.18 | 0.441 | |
| 1rkh | VD2 | Vitamin D3 receptor | / | 0.441 | |
| 1tl7 | FOK | Adenylate cyclase type 2 | / | 0.441 | |
| 1tl7 | FOK | Adenylate cyclase type 5 | / | 0.441 | |
| 1wlv | COA | Phenylacetic acid degradation protein PaaI | / | 0.441 | |
| 2gtk | 208 | Peroxisome proliferator-activated receptor gamma | / | 0.441 | |
| 2vww | 7X2 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.441 | |
| 2z1q | FAD | Acyl-CoA dehydrogenase | / | 0.441 | |
| 3fsu | C2F | 5,10-methylenetetrahydrofolate reductase | 1.5.1.20 | 0.441 | |
| 3gwf | FAD | Cyclohexanone monooxygenase | / | 0.441 | |
| 3ii4 | 3II | Dihydrolipoyl dehydrogenase | 1.8.1.4 | 0.441 | |
| 3iup | NDP | Possible NADH oxidoreductase | / | 0.441 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.441 | |
| 3p99 | LNP | Lanosterol 14-alpha-demethylase | / | 0.441 | |
| 3w5t | LHP | Vitamin D3 receptor | / | 0.441 | |
| 4g1y | 0VO | Vitamin D3 receptor A | / | 0.441 | |
| 4ge4 | 0KE | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.441 | |
| 4irn | FAD | AnaB | / | 0.441 | |
| 4o7u | THF | Thymidylate synthase | / | 0.441 | |
| 1n4h | REA | Nuclear receptor ROR-beta | / | 0.440 | |
| 1nzy | BCA | 4-chlorobenzoyl coenzyme A dehalogenase | 3.8.1.7 | 0.440 | |
| 1s0z | EB1 | Vitamin D3 receptor | / | 0.440 | |
| 2hb7 | O1C | Vitamin D3 receptor | / | 0.440 | |
| 2ic5 | GDP | Ras-related C3 botulinum toxin substrate 3 | / | 0.440 | |
| 2itt | AEE | Epidermal growth factor receptor | 2.7.10.1 | 0.440 | |
| 2w4q | CBW | Prostaglandin reductase 2 | 1.3.1.48 | 0.440 | |
| 3g5s | FAD | Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO | / | 0.440 | |
| 3ml9 | ML9 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.440 | |
| 3znp | FAD | D-amino-acid oxidase | 1.4.3.3 | 0.440 | |
| 4eut | BX7 | Serine/threonine-protein kinase TBK1 | 2.7.11.1 | 0.440 | |
| 4jbt | ASD | Cytochrome P450 monooxygenase | / | 0.440 | |
| 4nxv | GDP | Mitochondrial dynamics protein MID51 | / | 0.440 | |
| 4qmy | STU | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.440 | |
| 4wq5 | ATP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.440 |