sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1vot | HUP | Acetylcholinesterase | 3.1.1.7 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 1vot | HUP | Acetylcholinesterase | 3.1.1.7 | 1.000 | |
| 1gpn | HUB | Acetylcholinesterase | 3.1.1.7 | 0.794 | |
| 2cek | N8T | Acetylcholinesterase | 3.1.1.7 | 0.763 | |
| 1qti | GNT | Acetylcholinesterase | 3.1.1.7 | 0.713 | |
| 2w6c | BM4 | Acetylcholinesterase | 3.1.1.7 | 0.672 | |
| 1w4l | GL8 | Acetylcholinesterase | 3.1.1.7 | 0.654 | |
| 1zgb | A1E | Acetylcholinesterase | 3.1.1.7 | 0.638 | |
| 3zv7 | NHG | Acetylcholinesterase | 3.1.1.7 | 0.636 | |
| 1odc | A8B | Acetylcholinesterase | 3.1.1.7 | 0.625 | |
| 1w6r | GNT | Acetylcholinesterase | 3.1.1.7 | 0.621 | |
| 1e66 | HUX | Acetylcholinesterase | 3.1.1.7 | 0.620 | |
| 1h22 | E10 | Acetylcholinesterase | 3.1.1.7 | 0.617 | |
| 2ckm | AA7 | Acetylcholinesterase | 3.1.1.7 | 0.604 | |
| 2xuf | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.602 | |
| 1w76 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.601 | |
| 1ut6 | A8N | Acetylcholinesterase | 3.1.1.7 | 0.596 | |
| 4b7z | Q4Q | Acetylcholinesterase | 3.1.1.7 | 0.591 | |
| 4ey6 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.590 | |
| 2xuo | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.589 | |
| 2whq | HI6 | Acetylcholinesterase | 3.1.1.7 | 0.586 | |
| 2cmf | F11 | Acetylcholinesterase | 3.1.1.7 | 0.576 | |
| 2xuq | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.575 | |
| 2ha6 | SCK | Acetylcholinesterase | 3.1.1.7 | 0.571 | |
| 1u65 | CP0 | Acetylcholinesterase | 3.1.1.7 | 0.569 | |
| 2gyu | HI6 | Acetylcholinesterase | 3.1.1.7 | 0.569 | |
| 4arb | C57 | Acetylcholinesterase | 3.1.1.7 | 0.568 | |
| 2jf0 | HBP | Acetylcholinesterase | 3.1.1.7 | 0.566 | |
| 1dx6 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.560 | |
| 1eve | E20 | Acetylcholinesterase | 3.1.1.7 | 0.560 | |
| 4ara | C56 | Acetylcholinesterase | 3.1.1.7 | 0.558 | |
| 4m0f | 1YK | Acetylcholinesterase | 3.1.1.7 | 0.555 | |
| 2xuh | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.554 | |
| 2xuj | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.553 | |
| 1zgc | A2E | Acetylcholinesterase | 3.1.1.7 | 0.552 | |
| 4ey7 | E20 | Acetylcholinesterase | 3.1.1.7 | 0.552 | |
| 1q84 | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.550 | |
| 2xuk | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.550 | |
| 2j3q | TFL | Acetylcholinesterase | 3.1.1.7 | 0.549 | |
| 4a16 | H34 | Acetylcholinesterase | 3.1.1.7 | 0.547 | |
| 2xup | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.545 | |
| 2xui | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.544 | |
| 1p0p | BCH | Cholinesterase | 3.1.1.8 | 0.523 | |
| 3jsx | CC2 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.514 | |
| 2gyw | OBI | Acetylcholinesterase | 3.1.1.7 | 0.512 | |
| 3r8h | ZOM | Aldo-keto reductase family 1 member C3 | / | 0.495 | |
| 1ry0 | PG2 | Aldo-keto reductase family 1 member C3 | / | 0.492 | |
| 1jqd | SAH | Histamine N-methyltransferase | 2.1.1.8 | 0.491 | |
| 3g1r | FIT | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.488 | |
| 3gnc | QQQ | Glutaryl-CoA dehydrogenase | / | 0.484 | |
| 4drj | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.482 | |
| 4drj | RAP | Peptidyl-prolyl cis-trans isomerase FKBP4 | 5.2.1.8 | 0.482 | |
| 2g1n | 1IG | Renin | 3.4.23.15 | 0.479 | |
| 2i65 | NAD | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.478 | |
| 3cav | CI2 | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.477 | |
| 1oj4 | CDM | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | 2.7.1.148 | 0.476 | |
| 2a58 | RBF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.476 | |
| 3cot | STR | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.476 | |
| 2a0x | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.474 | |
| 5irn | ADP | Nucleotide binding oligomerization domain containing 2 | / | 0.474 | |
| 1efy | BZC | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.473 | |
| 3uzz | ASD | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.473 | |
| 4dbw | 511 | Aldo-keto reductase family 1 member C3 | / | 0.473 | |
| 1ry8 | RUT | Aldo-keto reductase family 1 member C3 | / | 0.472 | |
| 3hii | PNT | Amiloride-sensitive amine oxidase [copper-containing] | / | 0.472 | |
| 4e0u | 0MV | Cyclic dipeptide N-prenyltransferase | / | 0.472 | |
| 2il2 | LIX | Renin | 3.4.23.15 | 0.471 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.470 | |
| 1h60 | STR | Pentaerythritol tetranitrate reductase | / | 0.469 | |
| 1h69 | ARH | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.469 | |
| 1q83 | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.468 | |
| 1fap | RAP | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.467 | |
| 1fap | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.467 | |
| 1hb3 | SCV | Isopenicillin N synthase | 1.21.3.1 | 0.467 | |
| 1rsz | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.467 | |
| 2ixk | TDO | dTDP-4-dehydrorhamnose 3,5-epimerase | 5.1.3.13 | 0.467 | |
| 4mr7 | 2BV | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.467 | |
| 2c1z | KMP | Anthocyanidin 3-O-glucosyltransferase 2 | 2.4.1.115 | 0.466 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.466 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.466 | |
| 4rxq | DUT | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.466 | |
| 1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.465 | |
| 4dri | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.465 | |
| 4dri | RAP | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.465 | |
| 2fap | RAD | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.464 | |
| 2fap | RAD | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.464 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.464 | |
| 3u57 | DH8 | Raucaffricine-O-beta-D-glucosidase | 3.2.1.125 | 0.464 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.463 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.463 | |
| 3gjw | GJW | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.463 | |
| 3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.463 | |
| 4mr9 | 2BX | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.463 | |
| 3ggs | 2FD | Purine nucleoside phosphorylase | 2.4.2.1 | 0.462 | |
| 3ug8 | IMN | Aldo-keto reductase family 1 member C3 | / | 0.462 | |
| 4bfs | ZVS | Pantothenate kinase | 2.7.1.33 | 0.462 | |
| 1amo | FMN | NADPH--cytochrome P450 reductase | / | 0.461 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.461 | |
| 3dzk | NMN | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.461 | |
| 3hku | TOR | Carbonic anhydrase 2 | 4.2.1.1 | 0.461 | |
| 4bft | ZVT | Pantothenate kinase | 2.7.1.33 | 0.461 | |
| 1nsg | RAD | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.460 | |
| 1nsg | RAD | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.460 | |
| 1yw8 | A75 | Methionine aminopeptidase 2 | / | 0.460 | |
| 2g1y | 5IG | Renin | 3.4.23.15 | 0.460 | |
| 2wnb | C5P | CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1 | 2.4.99.4 | 0.460 | |
| 3s8p | SAM | Histone-lysine N-methyltransferase KMT5B | 2.1.1.43 | 0.460 | |
| 1ex7 | 5GP | Guanylate kinase | 2.7.4.8 | 0.459 | |
| 1tco | FK5 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.459 | |
| 1tco | FK5 | Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform | 3.1.3.16 | 0.459 | |
| 2ejz | SAH | Diphthine synthase | / | 0.459 | |
| 2g1r | 3IG | Renin | 3.4.23.15 | 0.459 | |
| 3hl0 | NAD | Maleylacetate reductase | / | 0.459 | |
| 1gky | 5GP | Guanylate kinase | 2.7.4.8 | 0.458 | |
| 1h66 | RH1 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.458 | |
| 1lke | DOG | Bilin-binding protein | / | 0.458 | |
| 1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.458 | |
| 2ges | COK | Pantothenate kinase | 2.7.1.33 | 0.458 | |
| 2zsd | COA | Pantothenate kinase | 2.7.1.33 | 0.458 | |
| 3tfu | PL8 | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase | 2.6.1.62 | 0.458 | |
| 4a95 | 9MT | Glycylpeptide N-tetradecanoyltransferase | / | 0.458 | |
| 4fap | ARD | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.458 | |
| 4fap | ARD | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.458 | |
| 4hhz | 15S | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.458 | |
| 1xh5 | R68 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.457 | |
| 2get | COK | Pantothenate kinase | 2.7.1.33 | 0.457 | |
| 3c1k | T15 | Prothrombin | 3.4.21.5 | 0.457 | |
| 3fap | ARD | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.457 | |
| 3fap | ARD | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.457 | |
| 4b11 | 7I1 | Glycylpeptide N-tetradecanoyltransferase | / | 0.457 | |
| 4q0k | GA3 | Phytohormone-binding protein | / | 0.457 | |
| 5dp2 | NAP | CurF | / | 0.457 | |
| 1x1d | SAH | C-20 methyltransferase | / | 0.456 | |
| 4tvj | 09L | Poly [ADP-ribose] polymerase 2 | 2.4.2.30 | 0.456 | |
| 2gev | COK | Pantothenate kinase | 2.7.1.33 | 0.455 | |
| 2xiq | 5AD | Methylmalonyl-CoA mutase, mitochondrial | / | 0.455 | |
| 2xje | U5P | Cytosolic purine 5'-nucleotidase | 3.1.3.5 | 0.455 | |
| 3apw | DP0 | Alpha-1-acid glycoprotein 2 | / | 0.455 | |
| 3nub | UD0 | UDP-2-acetamido-2-deoxy-3-oxo-D-glucuronate aminotransferase | 2.6.1.98 | 0.455 | |
| 3vil | SA0 | Beta-glucosidase | / | 0.455 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.454 | |
| 1c7o | PPG | Hemolysin | / | 0.454 | |
| 2cje | DUN | DUTPase | / | 0.454 | |
| 2geu | COK | Pantothenate kinase | 2.7.1.33 | 0.454 | |
| 3ele | PLP | Aminotransferase | / | 0.454 | |
| 3vyd | VYD | Renin | 3.4.23.15 | 0.454 | |
| 4cf6 | CBD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.454 | |
| 1a9c | GTP | GTP cyclohydrolase 1 | 3.5.4.16 | 0.453 | |
| 1lb9 | DNQ | Glutamate receptor 2 | / | 0.453 | |
| 1qjf | ACS | Isopenicillin N synthase | 1.21.3.1 | 0.453 | |
| 1x1b | SAH | C-20 methyltransferase | / | 0.453 | |
| 1x1c | SAH | C-20 methyltransferase | / | 0.453 | |
| 1yhj | R6C | Pyridoxal kinase | 2.7.1.35 | 0.453 | |
| 3uzx | AOM | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.453 | |
| 4a31 | 2CB | Glycylpeptide N-tetradecanoyltransferase | / | 0.453 | |
| 4b14 | 4XB | Glycylpeptide N-tetradecanoyltransferase | / | 0.453 | |
| 4bfz | ZVZ | Pantothenate kinase | 2.7.1.33 | 0.453 | |
| 1i5r | HYC | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.452 | |
| 1z71 | L17 | Prothrombin | 3.4.21.5 | 0.452 | |
| 1zgv | 501 | Prothrombin | 3.4.21.5 | 0.452 | |
| 2g5w | 8PG | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.452 | |
| 2rd6 | 78P | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.452 | |
| 2std | CRP | Scytalone dehydratase | 4.2.1.94 | 0.452 | |
| 3mj4 | URM | UDP-galactopyranose mutase | / | 0.452 | |
| 4bfu | ZVU | Pantothenate kinase | 2.7.1.33 | 0.452 | |
| 4bfw | ZVW | Pantothenate kinase | 2.7.1.33 | 0.452 | |
| 4cb4 | MGT | Polymerase basic protein 2 | / | 0.452 | |
| 4dy4 | FMN | NAD(P)H dehydrogenase (quinone) | / | 0.452 | |
| 4fhd | 0TT | Spore photoproduct lyase | / | 0.452 | |
| 4flk | Y10 | Methionine aminopeptidase 1 | / | 0.452 | |
| 1esm | COA | Pantothenate kinase | 2.7.1.33 | 0.451 | |
| 1ikg | REX | D-alanyl-D-alanine carboxypeptidase | 3.4.16.4 | 0.451 | |
| 1rkw | PNT | HTH-type transcriptional regulator QacR | / | 0.451 | |
| 3e34 | ED1 | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.451 | |
| 3e34 | ED1 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.451 | |
| 4b68 | FAD | L-ornithine N(5)-monooxygenase | / | 0.451 | |
| 4fgc | PQ0 | NADPH-dependent 7-cyano-7-deazaguanine reductase | 1.7.1.13 | 0.451 | |
| 1ygj | RMC | Pyridoxal kinase | 2.7.1.35 | 0.450 | |
| 2v16 | C47 | Renin | 3.4.23.15 | 0.450 | |
| 2xys | SY9 | Soluble acetylcholine receptor | / | 0.450 | |
| 3k8q | 22A | Purine nucleoside phosphorylase | 2.4.2.1 | 0.450 | |
| 3zho | FMN | NAD(P)H dehydrogenase (quinone) | / | 0.450 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.450 | |
| 4cb7 | 41G | Polymerase basic protein 2 | / | 0.450 | |
| 4nce | MGT | Polymerase basic protein 2 | / | 0.450 | |
| 1blz | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.449 | |
| 1rpw | DID | HTH-type transcriptional regulator QacR | / | 0.449 | |
| 1rr6 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.449 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.449 | |
| 3dzj | NMN | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.449 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.449 | |
| 4a86 | H35 | Major pollen allergen Bet v 1-A | / | 0.449 | |
| 4bfy | ZVY | Pantothenate kinase | 2.7.1.33 | 0.449 | |
| 2fm5 | M99 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.448 | |
| 2po3 | T4K | 4-dehydrase | / | 0.448 | |
| 3bv7 | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.448 | |
| 3jsi | WTC | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.448 | |
| 3nyt | ULP | UDP-2-acetamido-2-deoxy-3-oxo-D-glucuronate aminotransferase | 2.6.1.98 | 0.448 | |
| 3pke | Y10 | Methionine aminopeptidase 2 | / | 0.448 | |
| 4hcy | 0YN | Transketolase | / | 0.448 | |
| 4ms1 | 381 | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.448 | |
| 5std | UNN | Scytalone dehydratase | 4.2.1.94 | 0.448 | |
| 7std | CRP | Scytalone dehydratase | 4.2.1.94 | 0.448 | |
| 1rfg | GMP | Purine nucleoside phosphorylase | 2.4.2.1 | 0.447 | |
| 2e8u | IPE | Geranylgeranyl pyrophosphate synthase | / | 0.447 | |
| 3dcs | MZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.447 | |
| 3dys | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.447 | |
| 1kyx | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.446 | |
| 1r5g | AO1 | Methionine aminopeptidase 2 | / | 0.446 | |
| 1v3q | 2DI | Purine nucleoside phosphorylase | 2.4.2.1 | 0.446 | |
| 2v2z | CDM | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.446 | |
| 3qe2 | FMN | NADPH--cytochrome P450 reductase | / | 0.446 | |
| 4ax9 | N5N | Prothrombin | 3.4.21.5 | 0.446 | |
| 4gh6 | LUO | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.446 | |
| 4mrm | 2BY | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.446 | |
| 1vf3 | GDN | Glutathione S-transferase 3 | 2.5.1.18 | 0.445 | |
| 2idv | M7G | Eukaryotic translation initiation factor 4E-1 | / | 0.445 | |
| 2iko | 7IG | Renin | 3.4.23.15 | 0.445 | |
| 2y6f | M9F | Isopenicillin N synthase | 1.21.3.1 | 0.445 | |
| 3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.445 | |
| 3m1v | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.445 | |
| 3m1v | COM | Methyl-coenzyme M reductase I subunit beta | 2.8.4.1 | 0.445 | |
| 3n3z | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.445 | |
| 3own | 3OX | Renin | 3.4.23.15 | 0.445 | |
| 3ziu | LSS | Leucyl-tRNA synthetase | / | 0.445 | |
| 4mlp | 2CX | Cryptochrome-2 | / | 0.445 | |
| 1gg5 | E09 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.444 | |
| 1nqv | LMZ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.444 | |
| 1xoq | ROF | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.444 | |
| 2a0y | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.444 | |
| 2vf3 | GVS | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.444 | |
| 2vqz | MGT | Polymerase basic protein 2 | / | 0.444 | |
| 3dy8 | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.444 | |
| 1ta6 | 177 | Prothrombin | 3.4.21.5 | 0.443 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
| 2xi4 | AFT | Acetylcholinesterase | 3.1.1.7 | 0.443 | |
| 2y60 | M8F | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
| 3dr7 | GPD | GDP-perosamine synthase | / | 0.443 | |
| 3gwf | NAP | Cyclohexanone monooxygenase | / | 0.443 | |
| 4b4v | L34 | Bifunctional protein FolD | / | 0.443 | |
| 4drh | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.443 | |
| 4drh | RAP | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.443 | |
| 1gzu | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 | 2.7.7.1 | 0.442 | |
| 1pd9 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1pfy | MSP | Methionine--tRNA ligase | 6.1.1.10 | 0.442 | |
| 1uzw | CDH | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
| 2g24 | 7IG | Renin | 3.4.23.15 | 0.442 | |
| 2qim | ZEA | Class 10 plant pathogenesis-related protein | / | 0.442 | |
| 4eso | NAP | Putative oxidoreductase | / | 0.442 | |
| 4psb | GA3 | Cytokinin-specific binding protein | / | 0.442 | |
| 4std | BFS | Scytalone dehydratase | 4.2.1.94 | 0.442 | |
| 4wlj | IK2 | Kynurenine--oxoglutarate transaminase 1 | 2.6.1.7 | 0.442 | |
| 1rt9 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.441 | |
| 1yw7 | A41 | Methionine aminopeptidase 2 | / | 0.441 | |
| 2bn4 | FMN | NADPH--cytochrome P450 reductase | / | 0.441 | |
| 2fhj | H4Z | Formylmethanofuran--tetrahydromethanopterin formyltransferase | 2.3.1.101 | 0.441 | |
| 3g45 | 988 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.441 | |
| 3pqb | VGP | Putative oxidoreductase | / | 0.441 | |
| 3qeo | LLT | Deoxycytidine kinase | 2.7.1.74 | 0.441 | |
| 3tvq | DQH | Multifunctional cyclase-dehydratase-3-O-methyl transferase TcmN | 2.1.1 | 0.441 | |
| 3uzx | AOX | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.441 | |
| 2xvi | FAD | Putative flavin-containing monooxygenase | / | 0.440 | |
| 3dd8 | 2C7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.440 | |
| 3k3e | PDB | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.440 | |
| 3p0f | BAU | Uridine phosphorylase 2 | 2.4.2.3 | 0.440 | |
| 3q9b | B3N | Acetylpolyamine amidohydrolase | / | 0.440 | |
| 4f1l | 0RY | Poly [ADP-ribose] polymerase 14 | 2.4.2.30 | 0.440 | |
| 4lxj | LAN | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.440 |