sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1eou | SMS | Carbonic anhydrase 2 | 4.2.1.1 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 1eou | SMS | Carbonic anhydrase 2 | 4.2.1.1 | 1.000 | |
| 3m2y | BE0 | Carbonic anhydrase 2 | 4.2.1.1 | 0.662 | |
| 3oik | WZB | Carbonic anhydrase 2 | 4.2.1.1 | 0.646 | |
| 3sbi | E90 | Carbonic anhydrase 2 | 4.2.1.1 | 0.619 | |
| 3sbh | E65 | Carbonic anhydrase 2 | 4.2.1.1 | 0.618 | |
| 1oq5 | CEL | Carbonic anhydrase 2 | 4.2.1.1 | 0.615 | |
| 3mna | DWH | Carbonic anhydrase 2 | 4.2.1.1 | 0.611 | |
| 3m5e | JDR | Carbonic anhydrase 2 | 4.2.1.1 | 0.608 | |
| 4kni | E1E | Carbonic anhydrase 2 | 4.2.1.1 | 0.607 | |
| 4itp | 1GD | Carbonic anhydrase 2 | 4.2.1.1 | 0.603 | |
| 3mmf | D9H | Carbonic anhydrase 2 | 4.2.1.1 | 0.602 | |
| 2weg | FBV | Carbonic anhydrase 2 | 4.2.1.1 | 0.598 | |
| 3ffp | LC1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.595 | |
| 4kap | 1QV | Carbonic anhydrase 2 | 4.2.1.1 | 0.591 | |
| 1g1d | FSB | Carbonic anhydrase 2 | 4.2.1.1 | 0.590 | |
| 3oys | OYS | Carbonic anhydrase 2 | 4.2.1.1 | 0.589 | |
| 3mzc | S6I | Carbonic anhydrase 2 | 4.2.1.1 | 0.588 | |
| 1kwr | SG2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.586 | |
| 1if6 | FBU | Carbonic anhydrase 2 | 4.2.1.1 | 0.583 | |
| 3oim | VZ5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.583 | |
| 2x7t | WZB | Carbonic anhydrase 2 | 4.2.1.1 | 0.581 | |
| 1kwq | SG1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.579 | |
| 3eft | 3BS | Carbonic anhydrase 2 | 4.2.1.1 | 0.579 | |
| 3qyk | IE2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.576 | |
| 3n3j | WWV | Carbonic anhydrase 2 | 4.2.1.1 | 0.575 | |
| 3n0n | P9B | Carbonic anhydrase 2 | 4.2.1.1 | 0.572 | |
| 4knj | E1F | Carbonic anhydrase 2 | 4.2.1.1 | 0.572 | |
| 2h15 | B19 | Carbonic anhydrase 2 | 4.2.1.1 | 0.571 | |
| 2pow | I7C | Carbonic anhydrase 2 | 4.2.1.1 | 0.571 | |
| 3dbu | D8W | Carbonic anhydrase 2 | 4.2.1.1 | 0.571 | |
| 3f4x | KLT | Carbonic anhydrase 2 | 4.2.1.1 | 0.571 | |
| 1i90 | INM | Carbonic anhydrase 2 | 4.2.1.1 | 0.570 | |
| 2eu3 | FF3 | Carbonic anhydrase 2 | 4.2.1.1 | 0.570 | |
| 3s9t | E49 | Carbonic anhydrase 2 | 4.2.1.1 | 0.570 | |
| 1if4 | FBS | Carbonic anhydrase 2 | 4.2.1.1 | 0.569 | |
| 4m2v | BZ1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.569 | |
| 3m98 | E02 | Carbonic anhydrase 2 | 4.2.1.1 | 0.566 | |
| 3mho | J43 | Carbonic anhydrase 2 | 4.2.1.1 | 0.566 | |
| 3s8x | E59 | Carbonic anhydrase 2 | 4.2.1.1 | 0.566 | |
| 4ilx | 1EZ | Carbonic anhydrase 2 | 4.2.1.1 | 0.566 | |
| 3m96 | E38 | Carbonic anhydrase 2 | 4.2.1.1 | 0.564 | |
| 1ttm | 667 | Carbonic anhydrase 2 | 4.2.1.1 | 0.563 | |
| 3igp | DT7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.563 | |
| 1okn | STB | Carbonic anhydrase 2 | 4.2.1.1 | 0.559 | |
| 1xpz | 4TZ | Carbonic anhydrase 2 | 4.2.1.1 | 0.559 | |
| 3sax | E50 | Carbonic anhydrase 2 | 4.2.1.1 | 0.558 | |
| 1a42 | BZU | Carbonic anhydrase 2 | 4.2.1.1 | 0.556 | |
| 4ito | MPX | Carbonic anhydrase 2 | 4.2.1.1 | 0.552 | |
| 1if7 | SBR | Carbonic anhydrase 2 | 4.2.1.1 | 0.550 | |
| 3oy0 | OY0 | Carbonic anhydrase 2 | 4.2.1.1 | 0.550 | |
| 1g52 | F2B | Carbonic anhydrase 2 | 4.2.1.1 | 0.549 | |
| 2weh | FB1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.549 | |
| 3b4f | TUO | Carbonic anhydrase 2 | 4.2.1.1 | 0.549 | |
| 4bf6 | X0Q | Carbonic anhydrase 2 | 4.2.1.1 | 0.548 | |
| 3nb5 | R21 | Carbonic anhydrase 2 | 4.2.1.1 | 0.547 | |
| 4dz7 | D02 | Carbonic anhydrase 2 | 4.2.1.1 | 0.547 | |
| 4m2r | BZ1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.546 | |
| 1okl | MNS | Carbonic anhydrase 2 | 4.2.1.1 | 0.545 | |
| 3bet | CTF | Carbonic anhydrase 2 | 4.2.1.1 | 0.545 | |
| 1bn4 | AL9 | Carbonic anhydrase 2 | 4.2.1.1 | 0.544 | |
| 3oyq | OYQ | Carbonic anhydrase 2 | 4.2.1.1 | 0.543 | |
| 3m2n | J74 | Carbonic anhydrase 2 | 4.2.1.1 | 0.542 | |
| 3kig | DA4 | Carbonic anhydrase 2 | 4.2.1.1 | 0.541 | |
| 3t85 | SG7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.541 | |
| 1bnm | AL8 | Carbonic anhydrase 2 | 4.2.1.1 | 0.538 | |
| 3k2f | NKX | Carbonic anhydrase 2 | 4.2.1.1 | 0.538 | |
| 3ml2 | SU0 | Carbonic anhydrase 2 | 4.2.1.1 | 0.538 | |
| 4k0t | D9Z | Carbonic anhydrase 2 | 4.2.1.1 | 0.538 | |
| 3dd0 | EZL | Carbonic anhydrase 2 | 4.2.1.1 | 0.537 | |
| 1cnw | EG1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.536 | |
| 3dc3 | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.536 | |
| 1g4j | FFB | Carbonic anhydrase 2 | 4.2.1.1 | 0.535 | |
| 3dcc | D9Z | Carbonic anhydrase 2 | 4.2.1.1 | 0.535 | |
| 2wej | FB2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.534 | |
| 3mhc | ARZ | Carbonic anhydrase 2 | 4.2.1.1 | 0.533 | |
| 1cil | ETS | Carbonic anhydrase 2 | 4.2.1.1 | 0.532 | |
| 2weo | FBW | Carbonic anhydrase 2 | 4.2.1.1 | 0.532 | |
| 3p5l | IT5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.530 | |
| 1bnt | AL2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.529 | |
| 3hku | TOR | Carbonic anhydrase 2 | 4.2.1.1 | 0.527 | |
| 4mo8 | 2VQ | Carbonic anhydrase 2 | 4.2.1.1 | 0.527 | |
| 1bn1 | AL5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.526 | |
| 1bnn | AL1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.525 | |
| 1g45 | FSB | Carbonic anhydrase 2 | 4.2.1.1 | 0.525 | |
| 3n4b | WWZ | Carbonic anhydrase 2 | 4.2.1.1 | 0.525 | |
| 4bf1 | 9FK | Carbonic anhydrase 2 | 4.2.1.1 | 0.525 | |
| 1cny | EG3 | Carbonic anhydrase 2 | 4.2.1.1 | 0.524 | |
| 1g54 | FFB | Carbonic anhydrase 2 | 4.2.1.1 | 0.523 | |
| 3myq | E27 | Carbonic anhydrase 2 | 4.2.1.1 | 0.523 | |
| 1yda | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.522 | |
| 1bnv | AL7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.521 | |
| 2wd2 | MS5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.521 | |
| 3dcw | EZL | Carbonic anhydrase 2 | 4.2.1.1 | 0.521 | |
| 1i91 | INQ | Carbonic anhydrase 2 | 4.2.1.1 | 0.520 | |
| 3v2j | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.520 | |
| 3t84 | SG6 | Carbonic anhydrase 2 | 4.2.1.1 | 0.519 | |
| 1if8 | SBS | Carbonic anhydrase 2 | 4.2.1.1 | 0.518 | |
| 3dcs | MZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.517 | |
| 3dd8 | 2C7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.516 | |
| 4k13 | ETS | Carbonic anhydrase 2 | 4.2.1.1 | 0.516 | |
| 1bnw | TPD | Carbonic anhydrase 2 | 4.2.1.1 | 0.515 | |
| 1i8z | INL | Carbonic anhydrase 2 | 4.2.1.1 | 0.514 | |
| 3bl1 | BL1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.514 | |
| 1zsb | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.513 | |
| 5fl4 | 9FK | Carbonic anhydrase 9 | 4.2.1.1 | 0.512 | |
| 3po6 | DT9 | Carbonic anhydrase 2 | 4.2.1.1 | 0.511 | |
| 3t82 | SG4 | Carbonic anhydrase 2 | 4.2.1.1 | 0.511 | |
| 4pxx | CHD | Carbonic anhydrase 2 | 4.2.1.1 | 0.510 | |
| 3mdz | EZL | Carbonic anhydrase 7 | 4.2.1.1 | 0.509 | |
| 4k0z | MZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.508 | |
| 1bnq | AL4 | Carbonic anhydrase 2 | 4.2.1.1 | 0.506 | |
| 3rz8 | RZ8 | Carbonic anhydrase 2 | 4.2.1.1 | 0.506 | |
| 4n16 | CHD | Carbonic anhydrase 2 | 4.2.1.1 | 0.506 | |
| 3d8w | D8W | Carbonic anhydrase 2 | 4.2.1.1 | 0.504 | |
| 2x7u | WZA | Carbonic anhydrase 2 | 4.2.1.1 | 0.503 | |
| 3l14 | I7B | Carbonic anhydrase 2 | 4.2.1.1 | 0.502 | |
| 5flt | VJJ | Carbonic anhydrase 2 | 4.2.1.1 | 0.500 | |
| 1bnu | AL3 | Carbonic anhydrase 2 | 4.2.1.1 | 0.498 | |
| 3daz | MZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.497 | |
| 3n2p | AYX | Carbonic anhydrase 2 | 4.2.1.1 | 0.497 | |
| 1x1a | SAM | C-20 methyltransferase | / | 0.492 | |
| 1g4o | BSB | Carbonic anhydrase 2 | 4.2.1.1 | 0.491 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.491 | |
| 3znc | BZ1 | Carbonic anhydrase 4 | 4.2.1.1 | 0.490 | |
| 1i9n | IOA | Carbonic anhydrase 2 | 4.2.1.1 | 0.489 | |
| 1xq0 | 4TR | Carbonic anhydrase 2 | 4.2.1.1 | 0.489 | |
| 2a59 | LMZ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.489 | |
| 3fw3 | ETS | Carbonic anhydrase 4 | 4.2.1.1 | 0.489 | |
| 3m67 | E36 | Carbonic anhydrase 2 | 4.2.1.1 | 0.488 | |
| 4xiw | AZM | Carbonic anhydrase, alpha type | / | 0.487 | |
| 3m40 | J45 | Carbonic anhydrase 2 | 4.2.1.1 | 0.486 | |
| 2h4n | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.485 | |
| 1okm | SAB | Carbonic anhydrase 2 | 4.2.1.1 | 0.483 | |
| 4kp8 | E1G | Carbonic anhydrase 12 | 4.2.1.1 | 0.483 | |
| 1i9q | IOF | Carbonic anhydrase 2 | 4.2.1.1 | 0.479 | |
| 4kp5 | E1F | Carbonic anhydrase 12 | 4.2.1.1 | 0.478 | |
| 3mhl | J71 | Carbonic anhydrase 2 | 4.2.1.1 | 0.477 | |
| 4f1l | 0RY | Poly [ADP-ribose] polymerase 14 | 2.4.2.30 | 0.476 | |
| 4iwz | 1GO | Carbonic anhydrase 2 | 4.2.1.1 | 0.476 | |
| 1xl8 | 152 | Peroxisomal carnitine O-octanoyltransferase | 2.3.1.137 | 0.474 | |
| 2a57 | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.474 | |
| 3mhi | J90 | Carbonic anhydrase 2 | 4.2.1.1 | 0.474 | |
| 4x5s | AZM | Carbonic anhydrase (Carbonate dehydratase) | / | 0.474 | |
| 2g1n | 1IG | Renin | 3.4.23.15 | 0.473 | |
| 2gv8 | NDP | Thiol-specific monooxygenase | 1.14.13 | 0.472 | |
| 3f7b | AG5 | Carbonic anhydrase 4 | 4.2.1.1 | 0.472 | |
| 2g24 | 7IG | Renin | 3.4.23.15 | 0.471 | |
| 3h3q | H13 | Collagen type IV alpha-3-binding protein | / | 0.471 | |
| 1kyx | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.470 | |
| 2qim | ZEA | Class 10 plant pathogenesis-related protein | / | 0.470 | |
| 4kby | C2E | Stimulator of interferon genes protein | / | 0.470 | |
| 2cek | N8T | Acetylcholinesterase | 3.1.1.7 | 0.468 | |
| 3ni5 | C1H | Carbonic anhydrase 2 | 4.2.1.1 | 0.468 | |
| 1x1b | SAH | C-20 methyltransferase | / | 0.467 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.467 | |
| 4b4v | L34 | Bifunctional protein FolD | / | 0.467 | |
| 1rj6 | AZM | Carbonic anhydrase 14 | 4.2.1.1 | 0.465 | |
| 4lu3 | AZM | Carbonic anhydrase 14 | 4.2.1.1 | 0.464 | |
| 1ivs | VAA | Valine--tRNA ligase | 6.1.1.9 | 0.463 | |
| 2a58 | RBF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.463 | |
| 2q1u | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.463 | |
| 3gwf | NAP | Cyclohexanone monooxygenase | / | 0.463 | |
| 4bfw | ZVW | Pantothenate kinase | 2.7.1.33 | 0.463 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.462 | |
| 2q1q | OSP | Carbonic anhydrase 2 | 4.2.1.1 | 0.461 | |
| 4f0r | MTA | 5-methylthioadenosine/S-adenosylhomocysteine deaminase | / | 0.461 | |
| 2g1o | 2IG | Renin | 3.4.23.15 | 0.460 | |
| 4lut | DCS | Alanine racemase | / | 0.460 | |
| 1gpd | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.458 | |
| 4c71 | 7RD | 3-oxoacyl-ACP synthase | / | 0.458 | |
| 2q1s | NAI | Putative nucleotide sugar epimerase/ dehydratase | / | 0.457 | |
| 1cnf | FAD | Nitrate reductase [NADH] | 1.7.1.1 | 0.456 | |
| 1i9p | IOE | Carbonic anhydrase 2 | 4.2.1.1 | 0.456 | |
| 1nup | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.456 | |
| 2g21 | L1B | Renin | 3.4.23.15 | 0.456 | |
| 4mrm | 2BY | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.456 | |
| 1kyv | RBF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.455 | |
| 1xe6 | 5FP | Plasmepsin-2 | 3.4.23.39 | 0.455 | |
| 2ea2 | F77 | Methionine aminopeptidase 2 | / | 0.455 | |
| 3h3s | H15 | Collagen type IV alpha-3-binding protein | / | 0.455 | |
| 3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.455 | |
| 3ho9 | N3A | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.455 | |
| 4e2y | JHZ | Methyltransferase | / | 0.455 | |
| 1eno | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH], chloroplastic | 1.3.1.9 | 0.454 | |
| 4dja | FAD | (6-4) photolyase | / | 0.454 | |
| 4gdy | 0X1 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.454 | |
| 1bn3 | AL6 | Carbonic anhydrase 2 | 4.2.1.1 | 0.453 | |
| 4kp6 | 1S1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.453 | |
| 3d9z | D9Z | Carbonic anhydrase 2 | 4.2.1.1 | 0.452 | |
| 3rbq | GLY_ALA_GLY_ALA_DAO | Protein unc-119 homolog A | / | 0.452 | |
| 4kfq | KFQ | Glutamate receptor ionotropic, NMDA 1 | / | 0.452 | |
| 3jsi | WTC | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.451 | |
| 4gh6 | LUO | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.451 | |
| 1rne | C60 | Renin | 3.4.23.15 | 0.450 | |
| 2c9z | QUE | Anthocyanidin 3-O-glucosyltransferase 2 | 2.4.1.115 | 0.450 | |
| 2pzj | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.450 | |
| 2q7o | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.450 | |
| 4b2g | V1N | Uncharacterized protein | / | 0.450 | |
| 2whq | HI6 | Acetylcholinesterase | 3.1.1.7 | 0.449 | |
| 3fap | ARD | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.449 | |
| 3fap | ARD | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.449 | |
| 4r81 | FMN | Predicted NADH dehydrogenase | / | 0.449 | |
| 1dmy | AZM | Carbonic anhydrase 5A, mitochondrial | 4.2.1.1 | 0.448 | |
| 1jd0 | AZM | Carbonic anhydrase 12 | 4.2.1.1 | 0.448 | |
| 2g1s | 4IG | Renin | 3.4.23.15 | 0.448 | |
| 1h22 | E10 | Acetylcholinesterase | 3.1.1.7 | 0.447 | |
| 2xup | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.447 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.447 | |
| 3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.447 | |
| 1a5b | IGP | Tryptophan synthase alpha chain | / | 0.446 | |
| 3ioe | A7D | Pantothenate synthetase | 6.3.2.1 | 0.446 | |
| 4p9d | TMP | Deoxycytidylate deaminase | / | 0.446 | |
| 1if5 | FBT | Carbonic anhydrase 2 | 4.2.1.1 | 0.445 | |
| 2dxi | ATP | Glutamate--tRNA ligase | 6.1.1.17 | 0.445 | |
| 2g1r | 3IG | Renin | 3.4.23.15 | 0.445 | |
| 3f7u | AG4 | Carbonic anhydrase 4 | 4.2.1.1 | 0.445 | |
| 4a2z | VIQ | Glycylpeptide N-tetradecanoyltransferase | / | 0.445 | |
| 4c6z | TLE | 3-oxoacyl-ACP synthase | / | 0.445 | |
| 4g2j | 0WF | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.445 | |
| 4gdd | NAI | UDP-galactopyranose mutase | / | 0.445 | |
| 1qbq | HFP | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.444 | |
| 1qbq | HFP | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.444 | |
| 3af1 | GDP | Pantothenate kinase | 2.7.1.33 | 0.444 | |
| 3apw | DP0 | Alpha-1-acid glycoprotein 2 | / | 0.444 | |
| 3vsw | R31 | Renin | 3.4.23.15 | 0.444 | |
| 1e66 | HUX | Acetylcholinesterase | 3.1.1.7 | 0.443 | |
| 2g1y | 5IG | Renin | 3.4.23.15 | 0.443 | |
| 2i65 | NAD | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.443 | |
| 4c49 | HCY | Corticosteroid-binding globulin | / | 0.443 | |
| 4eag | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.443 | |
| 1cnx | EG2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.442 | |
| 3ha5 | SFG | Hydroxymycolate synthase MmaA4 | 2.1.1 | 0.442 | |
| 3iqh | TYR_ASP_ILE | Cysteine synthase | 2.5.1.47 | 0.442 | |
| 3wag | TYD | Glycosyltransferase | / | 0.442 | |
| 4b68 | NAP | L-ornithine N(5)-monooxygenase | / | 0.442 | |
| 4ht2 | V50 | Carbonic anhydrase 12 | 4.2.1.1 | 0.442 | |
| 1x1c | SAH | C-20 methyltransferase | / | 0.441 | |
| 1q51 | CAA | 1,4-dihydroxy-2-naphthoyl-CoA synthase | / | 0.440 | |
| 2g25 | TDK | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.440 | |
| 2iko | 7IG | Renin | 3.4.23.15 | 0.440 | |
| 2xuo | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.440 | |
| 3oqf | S51 | Renin | 3.4.23.15 | 0.440 | |
| 4mlp | 2CX | Cryptochrome-2 | / | 0.440 | |
| 5kwv | ANP | Pantothenate synthetase | / | 0.440 | |
| 7std | CRP | Scytalone dehydratase | 4.2.1.94 | 0.440 |