Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4h4w FAD Biphenyl dioxygenase ferredoxin reductase subunit

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
4h4w FADBiphenyl dioxygenase ferredoxin reductase subunit / 1.465
4h4s FADBiphenyl dioxygenase ferredoxin reductase subunit / 1.409
4h4y FADBiphenyl dioxygenase ferredoxin reductase subunit / 1.409
2gr1 FADFerredoxin reductase / 1.407
2yvf FADFerredoxin reductase / 1.407
4h4u FADBiphenyl dioxygenase ferredoxin reductase subunit / 1.389
4h4q FADBiphenyl dioxygenase ferredoxin reductase subunit / 1.374
4h50 FADBiphenyl dioxygenase ferredoxin reductase subunit / 1.346
4h4z FADBiphenyl dioxygenase ferredoxin reductase subunit / 1.178
4h4v FADBiphenyl dioxygenase ferredoxin reductase subunit / 1.156
4h4x FADBiphenyl dioxygenase ferredoxin reductase subunit / 1.153
4h4r FADBiphenyl dioxygenase ferredoxin reductase subunit / 1.134
2gr3 FADFerredoxin reductase / 1.126
4h4t FADBiphenyl dioxygenase ferredoxin reductase subunit / 1.120
2gr0 FADFerredoxin reductase / 1.113
2gqw FADFerredoxin reductase / 1.105
4h4p FADBiphenyl dioxygenase ferredoxin reductase subunit / 1.100
1d7y FADFerredoxin reductase / 1.093
1f3p FADFerredoxin reductase / 1.071
1q1r FADPutidaredoxin reductase 1.18.1.5 0.905
5fs9 FADApoptosis-inducing factor 1, mitochondrial 1.1.1 0.887
2yvj FADFerredoxin reductase / 0.876
1q1w FADPutidaredoxin reductase 1.18.1.5 0.846
1gv4 FADApoptosis-inducing factor 1, mitochondrial 1.1.1 0.845
1m6i FADApoptosis-inducing factor 1, mitochondrial 1.1.1 0.840
5fs6 FADApoptosis-inducing factor 1, mitochondrial 1.1.1 0.840
4bv6 FADApoptosis-inducing factor 1, mitochondrial 1.1.1 0.839
4lii FADApoptosis-inducing factor 1, mitochondrial 1.1.1 0.834
3lb8 FADPutidaredoxin reductase 1.18.1.5 0.831
3ef6 FADToluene 1,2-dioxygenase system ferredoxin--NAD(+) reductase component 1.18.1.3 0.830
5fs7 FADApoptosis-inducing factor 1, mitochondrial 1.1.1 0.828
3klj FADNADH-rubredoxin oxidoreductase 1.18.1.1 0.814
4bur FADApoptosis-inducing factor 1, mitochondrial 1.1.1 0.775
5fs8 FADApoptosis-inducing factor 1, mitochondrial 1.1.1 0.767
2dw4 FADLysine-specific histone demethylase 1A 1 0.755
3rha FDAPutrescine oxidase / 0.751
3kpf FADPolyamine oxidase 1.5.3.14 0.748
2uxx FAJLysine-specific histone demethylase 1A 1 0.742
1rsg FADPolyamine oxidase FMS1 / 0.739
2y48 FADLysine-specific histone demethylase 1A 1 0.735
4ocg FADFAD-dependent pyridine nucleotide-disulphide oxidoreductase / 0.734
3f8p NADNADH oxidase/thioredoxin reductase / 0.732
2yr5 FADPhenylalanine 2-monooxygenase precursor 1.13.12.9 0.728
4fwf FADLysine-specific histone demethylase 1B 1 0.723
2v3a FADRubredoxin-NAD(+) reductase 1.18.1.1 0.719
5er0 FADUncharacterized NAD(FAD)-dependent dehydrogenase / 0.719
4eqs FADCoenzyme A disulfide reductase / 0.716
2nvk FADThioredoxin reductase 1, mitochondrial 1.8.1.9 0.715
3kve FADL-amino-acid oxidase / 0.715
1w4x FADPhenylacetone monooxygenase 1.14.13.92 0.714
2yg7 FADPutrescine oxidase / 0.713
1h81 FADPolyamine oxidase 1.5.3.14 0.708
3icr FADCoenzyme A disulfide reductase / 0.708
1z6l FADPolyamine oxidase FMS1 / 0.706
1grb FADGlutathione reductase, mitochondrial 1.8.1.7 0.705
3ihg FADAklavinone 12-hydroxylase RdmE / 0.702
1d4c FADFumarate reductase flavoprotein subunit 1.3.5.4 0.701
3bi5 FADPolyamine oxidase FMS1 / 0.700
4emj FADToluene 1,2-dioxygenase system ferredoxin--NAD(+) reductase component 1.18.1.3 0.700
3cge FADCoenzyme A disulfide reductase / 0.699
2yg3 FADPutrescine oxidase / 0.698
2tmd ADPTrimethylamine dehydrogenase 1.5.8.2 0.697
2cdu FADNADH oxidase / 0.696
3nta FADFAD-dependent pyridine nucleotide-disulphide oxidoreductase / 0.696
4em4 FADCoenzyme A disulfide reductase / 0.695
3nt6 FADFAD-dependent pyridine nucleotide-disulphide oxidoreductase / 0.694
2yg5 FADPutrescine oxidase / 0.692
3ukf FDAUDP-galactopyranose mutase / 0.690
3bi2 FADPolyamine oxidase FMS1 / 0.689
1tdo FADL-amino-acid oxidase 1.4.3.2 0.688
3gdp FAD(R)-mandelonitrile lyase 2 4.1.2.10 0.688
3r9u FADThioredoxin reductase / 0.688
3k7t FAD6-hydroxy-L-nicotine oxidase / 0.684
1ju2 FAD(R)-mandelonitrile lyase 2 4.1.2.10 0.683
3k30 ADPHistamine dehydrogenase / 0.682
5l3d FADLysine-specific histone demethylase 1A 1 0.681
4j33 FADKynurenine 3-monooxygenase / 0.680
3gd3 FADApoptosis-inducing factor 1, mitochondrial 1.1.1 0.679
3ics FADCoenzyme A disulfide reductase / 0.679
3kkj FADRenalase / 0.679
4em3 FADCoenzyme A disulfide reductase / 0.678
1djq ADPTrimethylamine dehydrogenase 1.5.8.2 0.677
1f8s FADL-amino-acid oxidase 1.4.3.2 0.677
4u8o FDAUDP-galactopyranose mutase / 0.675
4emw FADCoenzyme A disulfide reductase / 0.674
2x8g FADThioredoxin glutathione reductase / 0.673
1ps9 FAD2,4-dienoyl-CoA reductase 1.3.1.34 0.672
2bra FAD[F-actin]-methionine sulfoxide oxidase MICAL1 1.14.13 0.672
4usr FADMonooxygenase / 0.671
2eq8 FADDihydrolipoyl dehydrogenase / 0.670
3lxd FADFAD-dependent pyridine nucleotide-disulfide oxidoreductase / 0.670
4k2x FADPolyketide oxygenase/hydroxylase / 0.670
5j60 FADThioredoxin reductase / 0.669
2bi8 FADUDP-galactopyranose mutase 5.4.99.9 0.668
2eq6 FADDihydrolipoyl dehydrogenase / 0.668
3cgb FADCoenzyme A disulfide reductase / 0.667
3cgd FADCoenzyme A disulfide reductase / 0.666
3utg FDAUDP-galactopyranose mutase / 0.666
3qj4 FADRenalase / 0.664
3kpk FADSulfide-quinone reductase / 0.663
4j57 FADThioredoxin reductase 2 1.8.1.9 0.663
4nte FADDepH / 0.663
2jb2 FADL-amino acid oxidase / 0.662
2yg4 FADPutrescine oxidase / 0.662
3cgc FADCoenzyme A disulfide reductase / 0.662
3ish FADThioredoxin reductase 1.8.1.9 0.662
3syi FADSulfide-quinone reductase / 0.662
4i58 FADCyclohexylamine Oxidase / 0.662
5js6 NAD17-beta-hydroxysteroid dehydrogenase 14 1.1.1 0.662
4mo2 FDAUDP-galactopyranose mutase / 0.661
1knr FADL-aspartate oxidase 1.4.3.16 0.660
3we0 FADLysine 2-monooxygenase / 0.659
1y56 ATPUncharacterized protein / 0.658
3he3 FADUDP-galactopyranose mutase / 0.657
3lzw FADFerredoxin--NADP reductase 2 1.18.1.2 0.657
2nli FMNLactate oxidase / 0.656
4mo2 FADUDP-galactopyranose mutase / 0.656
4wx1 FDAUDP-galactopyranose mutase / 0.656
1buc FADAcyl-CoA dehydrogenase, short-chain specific 1.3.8.1 0.655
2fje FADAdenylylsulfate reductase, subunit A (AprA) / 0.655
3uth FDAUDP-galactopyranose mutase / 0.655
4la1 FADThioredoxin glutathione reductase / 0.655
1cjc FADNADPH:adrenodoxin oxidoreductase, mitochondrial 1.18.1.6 0.654
2jae FADL-amino acid oxidase / 0.654
3ntd FADFAD-dependent pyridine nucleotide-disulphide oxidoreductase / 0.654
3utf FDAUDP-galactopyranose mutase / 0.654
4gcm FADThioredoxin reductase 1.8.1.9 0.654
4u8n FDAUDP-galactopyranose mutase / 0.654
1f8r FADL-amino-acid oxidase 1.4.3.2 0.653
2isl FNR5,6-dimethylbenzimidazole synthase 1.13.11.79 0.653
2jb1 FADL-amino acid oxidase / 0.653
2pg0 FADAcyl-CoA dehydrogenase / 0.653
3zdn FADMonoamine oxidase N 1.4.3.4 0.653
3k7m FAD6-hydroxy-L-nicotine oxidase / 0.652
1fl2 FADAlkyl hydroperoxide reductase subunit F 1.8.1 0.651
1gth FADDihydropyrimidine dehydrogenase [NADP(+)] 1.3.1.2 0.651
2fja FADAdenylylsulfate reductase, subunit A (AprA) / 0.651
3pl8 FADPyranose 2-oxidase / 0.651
1v0j FADUDP-galactopyranose mutase 5.4.99.9 0.650
2a1t FADMedium-chain specific acyl-CoA dehydrogenase, mitochondrial 1.3.8.7 0.650
3fg2 FADPutative rubredoxin reductase / 0.650