sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Modes are compared using Grim.
For more information, please see the following publication:
Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4dc1 | NDP | Putative ketoacyl reductase | 1.3.1 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Mode Similarity |
Align |
|---|---|---|---|---|---|
| 4dc1 | NDP | Putative ketoacyl reductase | 1.3.1 | 1.385 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 1.217 | |
| 1x7h | NDP | Putative ketoacyl reductase | 1.3.1 | 1.125 | |
| 4dc0 | NDP | Putative ketoacyl reductase | 1.3.1 | 1.120 | |
| 1w4z | NAP | Putative ketoacyl reductase | 1.3.1 | 1.094 | |
| 1x7g | NAP | Putative ketoacyl reductase | 1.3.1 | 1.034 | |
| 3ai2 | NDP | NADPH-sorbose reductase | / | 0.977 | |
| 3w8d | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.975 | |
| 3wds | NAD | NADH-dependent quinuclidinone reductase | / | 0.958 | |
| 3qrw | NDP | Putative ketoacyl reductase | 1.3.1 | 0.956 | |
| 3sju | NDP | Keto reductase | / | 0.953 | |
| 5js6 | NAD | 17-beta-hydroxysteroid dehydrogenase 14 | 1.1.1 | 0.949 | |
| 4rf2 | NAP | NADPH dependent R-specific alcohol dehydrogenase | / | 0.944 | |
| 3nug | NAD | Pyridoxal 4-dehydrogenase | 1.1.1.107 | 0.943 | |
| 4kwh | NAP | Reductase homolog | / | 0.926 | |
| 3w8f | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.919 | |
| 4b79 | NAD | Probable short-chain dehydrogenase | / | 0.919 | |
| 5jsf | NAD | 17-beta-hydroxysteroid dehydrogenase 14 | 1.1.1 | 0.909 | |
| 1vl8 | NAP | Oxidoreductase, short chain dehydrogenase/reductase family | / | 0.906 | |
| 2ztm | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.901 | |
| 1h5q | NAP | NADP-dependent mannitol dehydrogenase | 1.1.1.138 | 0.896 | |
| 4z3d | NDP | Carbonyl reductase [NADPH] 1 | 1.1.1.184 | 0.891 | |
| 1geg | NAD | Diacetyl reductase [(S)-acetoin forming] | 1.1.1.304 | 0.889 | |
| 3ai3 | NDP | NADPH-sorbose reductase | / | 0.885 | |
| 1xse | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.879 | |
| 3p19 | NDP | Putative blue fluorescent protein | / | 0.873 | |
| 2wsb | NAD | Galactitol dehydrogenase | / | 0.872 | |
| 3tn7 | NJP | Short-chain alcohol dehydrogenase | / | 0.872 | |
| 3pgx | NAD | Uncharacterized NAD-dependent oxidoreductase MAP_4146 | / | 0.869 | |
| 5ig2 | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.865 | |
| 1edo | NAP | 3-oxoacyl-[acyl-carrier-protein] reductase 1, chloroplastic | 1.1.1.100 | 0.861 | |
| 2o23 | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.861 | |
| 4fc7 | NAP | Peroxisomal 2,4-dienoyl-CoA reductase | 1.3.1.34 | 0.861 | |
| 2d1y | NAD | Oxidoreductase, short-chain dehydrogenase/reductase family | / | 0.860 | |
| 4bmv | NAP | Short-chain dehydrogenase | / | 0.859 | |
| 1ipe | NDP | Tropinone reductase 2 | 1.1.1.236 | 0.858 | |
| 4fn4 | NAD | Short chain dehydrogenase | / | 0.857 | |
| 2ztv | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.856 | |
| 2jah | NDP | Clavaldehyde dehydrogenase | / | 0.854 | |
| 3vdq | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.853 | |
| 4i5e | NAP | Alclohol dehydrogenase/short-chain dehydrogenase | / | 0.851 | |
| 4nbt | NAD | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.850 | |
| 3o4r | NAP | Dehydrogenase/reductase SDR family member 4 | 1.1.1.184 | 0.846 | |
| 1e6w | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.845 | |
| 3rj9 | NAD | Alcohol dehydrogenase | 1.1.1.1 | 0.844 | |
| 2q2v | NAD | Beta-D-hydroxybutyrate dehydrogenase | / | 0.843 | |
| 4dmm | NAP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.843 | |
| 2q2q | NAD | Beta-D-hydroxybutyrate dehydrogenase | / | 0.840 | |
| 1n5d | NDP | Carbonyl reductase [NADPH] 1 | / | 0.839 | |
| 3l77 | NJP | Short-chain alcohol dehydrogenase | / | 0.839 | |
| 4iqg | NAP | Short-chain dehydrogenase/reductase SDR | / | 0.839 | |
| 2dkn | NAI | 3-alpha-hydroxysteroid dehydrogenase | / | 0.837 | |
| 3w8e | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.833 | |
| 3g49 | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.831 | |
| 2bd0 | NAP | Sepiapterin reductase | / | 0.830 | |
| 4o0l | NDP | NADPH-dependent 3-quinuclidinone reductase | / | 0.828 | |
| 4yag | NAI | C alpha-dehydrogenase | / | 0.826 | |
| 3rj5 | NAD | Alcohol dehydrogenase | 1.1.1.1 | 0.825 | |
| 4qed | NAP | ElxO | / | 0.824 | |
| 3tsc | NAD | Uncharacterized protein | / | 0.823 | |
| 1cyd | NDP | Carbonyl reductase [NADPH] 2 | 1.1.1.184 | 0.820 | |
| 4hwk | NAP | Sepiapterin reductase | 1.1.1.153 | 0.817 | |
| 1gee | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.815 | |
| 1u7t | TDT | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.815 | |
| 2ztl | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.815 | |
| 1w8d | NAP | 2,4-dienoyl-CoA reductase, mitochondrial | 1.3.1.34 | 0.814 | |
| 3uce | NDP | Dehydrogenase | / | 0.814 | |
| 1fdu | NAP | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.812 | |
| 2dte | NAI | Glucose 1-dehydrogenase related protein | / | 0.810 | |
| 4j7u | NAP | Sepiapterin reductase | 1.1.1.153 | 0.808 | |
| 1e3s | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.807 | |
| 3ak4 | NAD | NADH-dependent quinuclidinone reductase | / | 0.807 | |
| 3o26 | NDP | Salutaridine reductase | / | 0.807 | |
| 5d2e | NAP | MlnE | / | 0.807 | |
| 1e3w | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.806 | |
| 5jla | NAD | Putative short-chain dehydrogenase/reductase | / | 0.806 | |
| 2zat | NAP | Dehydrogenase/reductase SDR family member 4 | 1.1.1.184 | 0.805 | |
| 1gco | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.799 | |
| 4qec | NAP | ElxO | / | 0.798 | |
| 1pr9 | NAP | L-xylulose reductase | 1.1.1.10 | 0.797 | |
| 3a28 | NAD | L-2,3-butanediol dehydrogenase | 1.1.1.76 | 0.796 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.796 | |
| 4nbu | NAI | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.796 | |
| 4tqg | NDP | Putative dTDP-d-glucose 4 6-dehydratase | / | 0.796 | |
| 4hxy | NDP | Plm1 | / | 0.795 | |
| 3bhi | NAP | Carbonyl reductase [NADPH] 1 | 1.1.1.184 | 0.794 | |
| 1u7t | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.791 | |
| 3gy0 | NAP | NAD(P)-dependent oxidoreductase | / | 0.790 | |
| 4gh5 | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.790 | |
| 2c29 | NAP | Dihydroflavonol 4-reductase | / | 0.788 | |
| 3r3s | NAD | Putative oxidoreductase | / | 0.788 | |
| 4imp | NDP | Polyketide synthase extender modules 3-4 | / | 0.787 | |
| 3ruh | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.786 | |
| 1g0n | NDP | Tetrahydroxynaphthalene reductase | 1.1.1.252 | 0.784 | |
| 2ekp | NAD | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.784 | |
| 3d3w | NAP | L-xylulose reductase | 1.1.1.10 | 0.784 | |
| 3u4c | NDP | NADPH-dependent reductase BacG | / | 0.783 | |
| 5idw | NAP | Short-chain dehydrogenase/reductase SDR | / | 0.783 | |
| 1ae1 | NAP | Tropinone reductase 1 | / | 0.782 | |
| 4is3 | NAD | 3alpha-hydroxy bile acid-CoA-ester 3-dehydrogenase 2 | 1.17.98.1 | 0.782 | |
| 2hrb | NAP | Carbonyl reductase [NADPH] 3 | 1.1.1.184 | 0.780 | |
| 4pvd | NDP | NADPH-dependent methylglyoxal reductase GRE2 | / | 0.778 | |
| 1xg5 | NAP | Dehydrogenase/reductase SDR family member 11 | / | 0.777 | |
| 4wec | NAD | Short chain dehydrogenase | / | 0.777 | |
| 3sx2 | NAD | Uncharacterized protein | / | 0.776 | |
| 2ag5 | NAD | 3-hydroxybutyrate dehydrogenase type 2 | / | 0.775 | |
| 2gn8 | NAP | UDP-N-acetylglucosamine 4,6-dehydratase (inverting) | 4.2.1.115 | 0.775 | |
| 4bms | NAP | Alclohol dehydrogenase/short-chain dehydrogenase | / | 0.775 | |
| 3ruc | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.770 | |
| 1nfr | NAD | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.768 | |
| 2b4q | NAP | Rhamnolipids biosynthesis 3-oxoacyl-[acyl-carrier-protein] reductase | 1.1.1.100 | 0.768 | |
| 3ruf | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.766 | |
| 1bdb | NAD | Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase | / | 0.765 | |
| 3s55 | NAD | Putative short-chain dehydrogenase/reductase | / | 0.763 | |
| 4yai | NAI | C alpha-dehydrogenase | / | 0.763 | |
| 1rwb | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.761 | |
| 3h4v | NAP | Pteridine reductase 1 | 1.5.1.33 | 0.761 | |
| 2rbe | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.759 | |
| 1oaa | NAP | Sepiapterin reductase | 1.1.1.153 | 0.755 | |
| 5jy1 | NAD | Putative short-chain dehydrogenase/reductase | / | 0.755 | |
| 2ztu | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.754 | |
| 3icp | NAD | NAD-dependent epimerase/dehydratase | / | 0.754 | |
| 4fj2 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.754 | |
| 1qyv | NAP | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.750 | |
| 3rue | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.750 | |
| 2yy7 | NAD | L-threonine dehydrogenase | / | 0.749 | |
| 2q1t | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.748 | |
| 2bfo | NDP | Pteridine reductase 1 | 1.5.1.33 | 0.747 | |
| 3geg | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.747 | |
| 3ndr | NAD | Pyridoxal 4-dehydrogenase | 1.1.1.107 | 0.747 | |
| 3rku | NAP | NADP-dependent 3-hydroxy acid dehydrogenase | / | 0.746 | |
| 1nah | NAD | UDP-glucose 4-epimerase | 5.1.3.2 | 0.745 | |
| 3qwf | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.745 | |
| 2wdz | NAD | Galactitol dehydrogenase | / | 0.744 | |
| 5jyd | NAD | Short chain dehydrogenase | / | 0.743 | |
| 1fk8 | NAD | 3-alpha-hydroxysteroid dehydrogenase/carbonyl reductase | 1.1.1.50 | 0.742 | |
| 2nnl | NAP | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.741 | |
| 2yut | NAP | Putative short-chain oxidoreductase | / | 0.741 | |
| 2q1w | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.740 | |
| 4u7w | NDP | MxaA | / | 0.739 | |
| 2hsd | NAD | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.738 | |
| 2p5u | NAD | UDP-glucose 4-epimerase | / | 0.738 | |
| 4clo | NAP | Pteridine reductase | / | 0.738 | |
| 2gdz | NAD | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | 1.1.1.141 | 0.737 | |
| 3mje | NDP | AmphB | / | 0.737 | |
| 3tox | NAP | Putative oxidoreductase | / | 0.735 | |
| 4j7x | NAP | Sepiapterin reductase | 1.1.1.153 | 0.735 | |
| 3iah | NAP | Putative oxoacyl-(Acyl carrier protein) reductase | / | 0.732 | |
| 3ru7 | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.732 | |
| 4lis | NAD | UDP-glucose 4-epimerase (Eurofung) | / | 0.732 | |
| 4fw8 | NAI | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.731 | |
| 3sj7 | NDP | 3-oxoacyl-(Acyl-carrier-protein) reductase, putative | / | 0.728 | |
| 1b16 | NAQ | Alcohol dehydrogenase | 1.1.1.1 | 0.727 | |
| 1nff | NAD | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.726 | |
| 3rud | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.726 | |
| 4eso | NAP | Putative oxidoreductase | / | 0.726 | |
| 2c59 | NAD | GDP-mannose 3,5-epimerase | 5.1.3.18 | 0.723 | |
| 2y99 | NAD | Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase | 1.3.1.56 | 0.723 | |
| 3ko8 | NAD | NAD-dependent epimerase/dehydratase | / | 0.723 | |
| 1b15 | NAE | Alcohol dehydrogenase | 1.1.1.1 | 0.721 | |
| 3lu1 | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.721 | |
| 3bmo | NAP | Pteridine reductase | / | 0.718 | |
| 4m87 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.718 | |
| 5j23 | A2R | Putative 2-hydroxyacid dehydrogenase | / | 0.718 | |
| 4ej0 | NAP | ADP-L-glycero-D-manno-heptose-6-epimerase | / | 0.717 | |
| 1b2l | NDC | Alcohol dehydrogenase | 1.1.1.1 | 0.716 | |
| 4fj1 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.716 | |
| 1xkq | NDP | Uncharacterized protein | / | 0.715 | |
| 1g6k | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.713 | |
| 1sby | NAD | Alcohol dehydrogenase | 1.1.1.1 | 0.711 | |
| 1i3l | NAD | UDP-glucose 4-epimerase | / | 0.710 | |
| 1kvr | NAD | UDP-glucose 4-epimerase | 5.1.3.2 | 0.710 | |
| 4zju | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.710 | |
| 5bt9 | NAP | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.710 | |
| 2idz | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.708 | |
| 1w73 | NAP | 2,4-dienoyl-CoA reductase, mitochondrial | 1.3.1.34 | 0.707 | |
| 5b1y | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.707 | |
| 1mg5 | NAI | Alcohol dehydrogenase | 1.1.1.1 | 0.706 | |
| 3aut | NAI | Glucose 1-dehydrogenase 4 | 1.1.1.47 | 0.706 | |
| 4hbg | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | 1.1.1.100 | 0.706 | |
| 2q1u | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.705 | |
| 4gll | NAD | UDP-glucuronic acid decarboxylase 1 | 4.1.1.35 | 0.705 | |
| 2q1s | NAI | Putative nucleotide sugar epimerase/ dehydratase | / | 0.704 | |
| 2wyv | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.703 | |
| 4trn | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.703 | |
| 1orr | NAD | CDP-paratose 2-epimerase | / | 0.700 | |
| 5ein | NAP | [LysW]-L-2-aminoadipate 6-phosphate reductase | / | 0.700 | |
| 2b69 | NAD | UDP-glucuronic acid decarboxylase 1 | 4.1.1.35 | 0.699 | |
| 3o03 | NAP | Dehydrogenase with different specificities (Related to short-chain alcohol dehydrogenase) | / | 0.698 | |
| 4fj0 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.698 | |
| 5lc1 | NAD | L-threonine 3-dehydrogenase | / | 0.698 | |
| 2b37 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.697 | |
| 3a4v | NAD | NDP-sugar epimerase | / | 0.696 | |
| 3uic | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.696 | |
| 5eio | NAP | [LysW]-L-2-aminoadipate 6-phosphate reductase | / | 0.695 | |
| 3rua | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.693 | |
| 2hun | NAD | 336aa long hypothetical dTDP-glucose 4,6-dehydratase | / | 0.692 | |
| 2ggs | NDP | dTDP-4-dehydrorhamnose reductase | / | 0.689 | |
| 3baz | NAP | Hydroxyphenylpyruvate reductase | 1.1.1.237 | 0.688 | |
| 2ieb | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.687 | |
| 3oey | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.687 | |
| 3of2 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.687 | |
| 4bii | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.686 | |
| 2bgm | NAJ | Secoisolariciresinol dehydrogenase | 1.1.1.331 | 0.685 | |
| 3uxy | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.685 | |
| 2p5y | NAD | UDP-glucose 4-epimerase | / | 0.684 | |
| 1eq2 | NAP | ADP-L-glycero-D-manno-heptose-6-epimerase | / | 0.682 | |
| 3aw9 | NAD | NAD-dependent epimerase/dehydratase | / | 0.682 | |
| 3ijr | NAD | Oxidoreductase, short chain dehydrogenase/reductase family | / | 0.681 | |
| 1zem | NAD | Xylitol dehydrogenase | / | 0.680 | |
| 3ru9 | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.680 | |
| 5cpb | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.680 | |
| 1e7y | NDP | Glucose-6-phosphate 1-dehydrogenase | / | 0.679 | |
| 2ie0 | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.679 | |
| 2pzj | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.679 | |
| 4cql | NAD | Estradiol 17-beta-dehydrogenase 8 | 1.1.1.62 | 0.678 | |
| 4b8z | NAP | GDP-L-fucose synthase | 1.1.1.271 | 0.677 | |
| 4hp8 | NAP | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.677 | |
| 1eny | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.673 | |
| 3abi | NAD | Uncharacterized protein | / | 0.673 | |
| 4bkq | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.673 | |
| 4xgi | NAD | Glutamate dehydrogenase | / | 0.673 | |
| 2b35 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.671 | |
| 2nv6 | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.671 | |
| 2c54 | NAD | GDP-mannose 3,5-epimerase | 5.1.3.18 | 0.670 | |
| 2v6g | NAP | 3-oxo-Delta(4,5)-steroid 5-beta-reductase | / | 0.670 | |
| 1ahh | NAD | 7-alpha-hydroxysteroid dehydrogenase | 1.1.1.159 | 0.669 | |
| 1sny | NAP | LD36273p | / | 0.668 | |
| 4twr | NAD | NAD binding site:NAD-dependent epimerase/dehydratase:UDP-glucose 4-epimerase | / | 0.668 | |
| 3phi | NDP | Shikimate dehydrogenase (NADP(+)) | / | 0.667 | |
| 4yr9 | NAD | L-threonine 3-dehydrogenase, mitochondrial | 1.1.1.103 | 0.666 | |
| 3qvx | NAD | Myo-inositol-1-phosphate synthase (Ino1) | / | 0.665 | |
| 1zha | PEP | 2-dehydro-3-deoxyphosphooctonate aldolase | 2.5.1.55 | 0.662 | |
| 3h2s | NDP | Putative NADH-flavin reductase | / | 0.662 | |
| 1iy8 | NAD | Levodione reductase | / | 0.660 | |
| 1t8x | PEP | 2-dehydro-3-deoxyphosphooctonate aldolase | 2.5.1.55 | 0.660 | |
| 4wji | NAP | Putative cyclohexadienyl dehydrogenase and ADH prephenate dehydrogenase | / | 0.660 | |
| 4xyb | NDP | Formate dehydrogenase | / | 0.660 | |
| 3sxp | NAD | ADP-L-glycero-D-mannoheptose-6-epimerase | / | 0.659 | |
| 2aqh | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.657 | |
| 2pk3 | A2R | GDP-6-deoxy-D-mannose reductase | / | 0.656 | |
| 3ehe | NAD | UDP-glucose 4-epimerase (GalE-1) | / | 0.656 | |
| 3iup | NDP | Possible NADH oxidoreductase | / | 0.656 | |
| 1nai | NAD | UDP-glucose 4-epimerase | 5.1.3.2 | 0.655 | |
| 5ero | 210 | Fusicoccadiene synthase | 2.5.1.29 | 0.655 | |
| 2rcy | NAP | Pyrroline-5-carboxylate reductase | / | 0.654 | |
| 4bqp | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.654 | |
| 1bxk | NAD | dTDP-glucose 4,6-dehydratase 2 | / | 0.653 | |
| 1g1a | NAD | dTDP-glucose 4,6-dehydratase | / | 0.653 | |
| 3au8 | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic | 1.1.1.267 | 0.653 | |
| 3pef | NAP | Glyoxalate/3-oxopropanoate/4-oxobutanoate reductase | / | 0.653 | |
| 4b8w | NAP | GDP-L-fucose synthase | 1.1.1.271 | 0.653 | |
| 1i36 | NAP | Conserved protein | / | 0.652 | |
| 4zwg | DTP | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.652 | |
| 1ek5 | NAD | UDP-glucose 4-epimerase | / | 0.651 | |
| 2jl1 | NAP | Triphenylmethane reductase | / | 0.651 | |
| 2vq3 | NAP | Metalloreductase STEAP3 | / | 0.651 | |
| 2x86 | NAP | ADP-L-glycero-D-manno-heptose-6-epimerase | / | 0.650 | |
| 4y9d | NAI | C alpha-dehydrogenase | / | 0.650 |