Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3oey NAD Enoyl-[acyl-carrier-protein] reductase [NADH] 1.3.1.9

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
3oey NADEnoyl-[acyl-carrier-protein] reductase [NADH] 1.3.1.9 1.171
3of2 NADEnoyl-[acyl-carrier-protein] reductase [NADH] 1.3.1.9 1.147
2aq8 NAIEnoyl-[acyl-carrier-protein] reductase [NADH] 1.3.1.9 1.103
4trn NADEnoyl-[acyl-carrier-protein] reductase [NADH] 1.3.1.9 1.094
4bii NADEnoyl-[acyl-carrier-protein] reductase [NADH] 1.3.1.9 1.085
3oew NADEnoyl-[acyl-carrier-protein] reductase [NADH] 1.3.1.9 1.074
4dre NAIEnoyl-[acyl-carrier-protein] reductase [NADH] 1.3.1.9 1.038
2aqh NAIEnoyl-[acyl-carrier-protein] reductase [NADH] 1.3.1.9 1.034
4bqp NADEnoyl-[acyl-carrier-protein] reductase [NADH] 1.3.1.9 1.034
2aqk NAIEnoyl-[acyl-carrier-protein] reductase [NADH] 1.3.1.9 1.027
4dti NAIEnoyl-[acyl-carrier-protein] reductase [NADH] 1.3.1.9 1.027
2aqi NAIEnoyl-[acyl-carrier-protein] reductase [NADH] 1.3.1.9 1.012
2b35 NADEnoyl-[acyl-carrier-protein] reductase [NADH] 1.3.1.9 1.008
2nv6 ZIDEnoyl-[acyl-carrier-protein] reductase [NADH] 1.3.1.9 0.995
4zju NADEnoyl-[acyl-carrier-protein] reductase [NADH] / 0.986
1eny NADEnoyl-[acyl-carrier-protein] reductase [NADH] 1.3.1.9 0.978
2b37 NADEnoyl-[acyl-carrier-protein] reductase [NADH] 1.3.1.9 0.970
4oxy NADEnoyl-[acyl-carrier-protein] reductase [NADH] 1.3.1.9 0.958
4bgi NADEnoyl-[acyl-carrier-protein] reductase [NADH] 1.3.1.9 0.946
2idz ZIDEnoyl-[acyl-carrier-protein] reductase [NADH] 1.3.1.9 0.945
4dqu NAIEnoyl-[acyl-carrier-protein] reductase [NADH] 1.3.1.9 0.933
5cpb NADEnoyl-[acyl-carrier-protein] reductase [NADH] 1.3.1.9 0.926
2ieb ZIDEnoyl-[acyl-carrier-protein] reductase [NADH] 1.3.1.9 0.912
4m87 NADEnoyl-[acyl-carrier-protein] reductase [NADH] / 0.898
3uic NADEnoyl-[acyl-carrier-protein] reductase [NADH] / 0.893
2h9i EADEnoyl-[acyl-carrier-protein] reductase [NADH] 1.3.1.9 0.886
2ntv P1HEnoyl-[acyl-carrier-protein] reductase [NADH] / 0.880
2ie0 ZIDEnoyl-[acyl-carrier-protein] reductase [NADH] 1.3.1.9 0.879
2ntj P1HEnoyl-[acyl-carrier-protein] reductase [NADH] 1.3.1.9 0.859
2b36 NADEnoyl-[acyl-carrier-protein] reductase [NADH] 1.3.1.9 0.852
5koi NADEnoyl-[acyl-carrier-protein] reductase [NADH] / 0.851
4qxm NADEnoyl-[acyl-carrier-protein] reductase [NADH] 1.3.1.9 0.849
2wyv NADEnoyl-[acyl-carrier-protein] reductase [NADH] / 0.801
3r3s NADPutative oxidoreductase / 0.798
3rj9 NADAlcohol dehydrogenase 1.1.1.1 0.794
1enz NADEnoyl-[acyl-carrier-protein] reductase [NADH] 1.3.1.9 0.779
4k6f NAPPutative Acetoacetyl-CoA reductase / 0.774
3rj5 NADAlcohol dehydrogenase 1.1.1.1 0.771
1p44 NADEnoyl-[acyl-carrier-protein] reductase [NADH] 1.3.1.9 0.770
2pr2 DG1Enoyl-[acyl-carrier-protein] reductase [NADH] 1.3.1.9 0.765
3bhi NAPCarbonyl reductase [NADPH] 1 1.1.1.184 0.763
1vl8 NAPOxidoreductase, short chain dehydrogenase/reductase family / 0.760
3vdq NAD3-hydroxybutyrate dehydrogenase / 0.760
3ijr NADOxidoreductase, short chain dehydrogenase/reductase family / 0.757
2q2v NADBeta-D-hydroxybutyrate dehydrogenase / 0.756
3iah NAPPutative oxoacyl-(Acyl carrier protein) reductase / 0.756
1n5d NDPCarbonyl reductase [NADPH] 1 / 0.755
2yw9 NAPEnoyl-[acyl-carrier-protein] reductase [NADH] / 0.754
1sny NAPLD36273p / 0.752
2yut NAPPutative short-chain oxidoreductase / 0.748
3gy0 NAPNAD(P)-dependent oxidoreductase / 0.748
4hp8 NAP2-deoxy-D-gluconate 3-dehydrogenase / 0.747
3pgx NADUncharacterized NAD-dependent oxidoreductase MAP_4146 / 0.742
2ztl NADD(-)-3-hydroxybutyrate dehydrogenase / 0.741
4b79 NADProbable short-chain dehydrogenase / 0.741
1bvr NADEnoyl-[acyl-carrier-protein] reductase [NADH] 1.3.1.9 0.740
2o23 NAD3-hydroxyacyl-CoA dehydrogenase type-2 1.1.1.35 0.740
3ak4 NADNADH-dependent quinuclidinone reductase / 0.739
3sxp NADADP-L-glycero-D-mannoheptose-6-epimerase / 0.739
1e6w NAD3-hydroxyacyl-CoA dehydrogenase type-2 1.1.1.35 0.737
1h5q NAPNADP-dependent mannitol dehydrogenase 1.1.1.138 0.737
3p19 NDPPutative blue fluorescent protein / 0.735
2q1u NADPutative nucleotide sugar epimerase/ dehydratase / 0.734
1gee NADGlucose 1-dehydrogenase 1.1.1.47 0.733
3wds NADNADH-dependent quinuclidinone reductase / 0.733
1zid ZIDEnoyl-[acyl-carrier-protein] reductase [NADH] 1.3.1.9 0.732
3w8e NAD3-hydroxybutyrate dehydrogenase / 0.732
4lis NADUDP-glucose 4-epimerase (Eurofung) / 0.732
3mje NDPAmphB / 0.731
5ig2 NADShort-chain dehydrogenase/reductase SDR / 0.731
5js6 NAD17-beta-hydroxysteroid dehydrogenase 14 1.1.1 0.731
4gll NADUDP-glucuronic acid decarboxylase 1 4.1.1.35 0.729
4pvd NDPNADPH-dependent methylglyoxal reductase GRE2 / 0.729
3o03 NAPDehydrogenase with different specificities (Related to short-chain alcohol dehydrogenase) / 0.727
2p5y NADUDP-glucose 4-epimerase / 0.726
1mg5 NAIAlcohol dehydrogenase 1.1.1.1 0.725
5jyd NADShort chain dehydrogenase / 0.722
4hxy NDPPlm1 / 0.721
3w8d NAD3-hydroxybutyrate dehydrogenase / 0.719
4is3 NAD3alpha-hydroxy bile acid-CoA-ester 3-dehydrogenase 2 1.17.98.1 0.719
1rkx NADCDP-D-glucose-4,6-dehydratase / 0.716
1rwb NADGlucose 1-dehydrogenase 1.1.1.47 0.716
2q1s NAIPutative nucleotide sugar epimerase/ dehydratase / 0.716
3w8f NAD3-hydroxybutyrate dehydrogenase / 0.716
3a28 NADL-2,3-butanediol dehydrogenase 1.1.1.76 0.715
3ai2 NDPNADPH-sorbose reductase / 0.715
3s55 NADPutative short-chain dehydrogenase/reductase / 0.715
5jsf NAD17-beta-hydroxysteroid dehydrogenase 14 1.1.1 0.713
1sby NADAlcohol dehydrogenase 1.1.1.1 0.712
2d1y NADOxidoreductase, short-chain dehydrogenase/reductase family / 0.712
3nug NADPyridoxal 4-dehydrogenase 1.1.1.107 0.712
4z3d NDPCarbonyl reductase [NADPH] 1 1.1.1.184 0.711
1e3w NAD3-hydroxyacyl-CoA dehydrogenase type-2 1.1.1.35 0.709
1x7h NDPPutative ketoacyl reductase 1.3.1 0.709
2c59 NADGDP-mannose 3,5-epimerase 5.1.3.18 0.709
2hrb NAPCarbonyl reductase [NADPH] 3 1.1.1.184 0.708
4kwh NAPReductase homolog / 0.708
1gco NADGlucose 1-dehydrogenase 1.1.1.47 0.707
1w8d NAP2,4-dienoyl-CoA reductase, mitochondrial 1.3.1.34 0.707
4o1m NADEnoyl-acyl carrier reductase / 0.707
5d2e NAPMlnE / 0.707
3sx2 NADUncharacterized protein / 0.706
2gdz NAD15-hydroxyprostaglandin dehydrogenase [NAD(+)] 1.1.1.141 0.705
1x7g NAPPutative ketoacyl reductase 1.3.1 0.704
4wec NADShort chain dehydrogenase / 0.704
2jah NDPClavaldehyde dehydrogenase / 0.703
2pzj NADPutative nucleotide sugar epimerase/ dehydratase / 0.703
4qed NAPElxO / 0.703
3uxy NADShort-chain dehydrogenase/reductase SDR / 0.700
4bmv NAPShort-chain dehydrogenase / 0.698
4qec NAPElxO / 0.698
2ztm NADD(-)-3-hydroxybutyrate dehydrogenase / 0.696
2ztu NADD(-)-3-hydroxybutyrate dehydrogenase / 0.696
2ztv NADD(-)-3-hydroxybutyrate dehydrogenase / 0.695
4hbg NDP3-oxoacyl-[acyl-carrier-protein] reductase 1.1.1.100 0.694
1enp NADEnoyl-[acyl-carrier-protein] reductase [NADH], chloroplastic 1.3.1.9 0.693
4u7w NDPMxaA / 0.693
1v35 NAIEnoyl-ACP reductase / 0.692
1w73 NAP2,4-dienoyl-CoA reductase, mitochondrial 1.3.1.34 0.692
2q2q NADBeta-D-hydroxybutyrate dehydrogenase / 0.691
3icp NADNAD-dependent epimerase/dehydratase / 0.691
1i3l NADUDP-glucose 4-epimerase / 0.690
1nff NAD3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase 1.1.1.53 0.690
2dkn NAI3-alpha-hydroxysteroid dehydrogenase / 0.690
4nbt NAD3-oxoacyl-[acyl-carrier-protein] reductase / 0.690
1nfr NAD3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase 1.1.1.53 0.689
3ai3 NDPNADPH-sorbose reductase / 0.688
3o26 NDPSalutaridine reductase / 0.688
3rku NAPNADP-dependent 3-hydroxy acid dehydrogenase / 0.688
1qyv NAPEstradiol 17-beta-dehydrogenase 1 1.1.1.62 0.687
3tn7 NJPShort-chain alcohol dehydrogenase / 0.687
4dc1 NDPPutative ketoacyl reductase 1.3.1 0.687
4fj1 NAP17beta-hydroxysteroid dehydrogenase / 0.687
4gh5 NADShort-chain dehydrogenase/reductase SDR / 0.687
1b16 NAQAlcohol dehydrogenase 1.1.1.1 0.686
1vrw NAIEnoyl-ACP reductase / 0.686
3qrw NDPPutative ketoacyl reductase 1.3.1 0.686
1edo NAP3-oxoacyl-[acyl-carrier-protein] reductase 1, chloroplastic 1.1.1.100 0.685
1i2b NADUDP-sulfoquinovose synthase, chloroplastic 3.13.1.1 0.685
2q1t NADPutative nucleotide sugar epimerase/ dehydratase / 0.685
5jla NADPutative short-chain dehydrogenase/reductase / 0.685
1u7t TDT3-hydroxyacyl-CoA dehydrogenase type-2 1.1.1.35 0.684
1xg5 NAPDehydrogenase/reductase SDR family member 11 / 0.683
1iy8 NADLevodione reductase / 0.682
2nq8 ZIDEnoyl-ACP reductase / 0.682
4iqg NAPShort-chain dehydrogenase/reductase SDR / 0.682
5bt9 NAP3-oxoacyl-(Acyl-carrier-protein) reductase / 0.682
2wdz NADGalactitol dehydrogenase / 0.681
2zat NAPDehydrogenase/reductase SDR family member 4 1.1.1.184 0.680
2nnl NAPDihydroflavonol 4-reductase 1.1.1.219 0.678
4cql NADEstradiol 17-beta-dehydrogenase 8 1.1.1.62 0.677
1geg NADDiacetyl reductase [(S)-acetoin forming] 1.1.1.304 0.676
4nbu NAI3-oxoacyl-(Acyl-carrier-protein) reductase / 0.676
1fdu NAPEstradiol 17-beta-dehydrogenase 1 1.1.1.62 0.675
4b8z NAPGDP-L-fucose synthase 1.1.1.271 0.675
1pr9 NAPL-xylulose reductase 1.1.1.10 0.674
4hwk NAPSepiapterin reductase 1.1.1.153 0.674
3orf NADDihydropteridine reductase 1.5.1.34 0.673
1b14 NADAlcohol dehydrogenase 1.1.1.1 0.672
3l77 NJPShort-chain alcohol dehydrogenase / 0.672
4eue NAITrans-2-enoyl-CoA reductase [NADH] / 0.672
1cyd NDPCarbonyl reductase [NADPH] 2 1.1.1.184 0.671
3a9w NADNDP-sugar epimerase / 0.671
4dmm NAP3-oxoacyl-[acyl-carrier-protein] reductase / 0.671
1e3s NAD3-hydroxyacyl-CoA dehydrogenase type-2 1.1.1.35 0.670
1kvr NADUDP-glucose 4-epimerase 5.1.3.2 0.670
4dc0 NDPPutative ketoacyl reductase 1.3.1 0.670
1b15 NAEAlcohol dehydrogenase 1.1.1.1 0.669
2dte NAIGlucose 1-dehydrogenase related protein / 0.669
2yy7 NADL-threonine dehydrogenase / 0.669
4fj0 NAP17beta-hydroxysteroid dehydrogenase / 0.669
2ag5 NAD3-hydroxybutyrate dehydrogenase type 2 / 0.668
2wsb NADGalactitol dehydrogenase / 0.668
4c7k NAPCorticosteroid 11-beta-dehydrogenase isozyme 1 1.1.1.146 0.668
2y99 NADCis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase 1.3.1.56 0.667
3geg NADShort-chain dehydrogenase/reductase SDR / 0.667
3ru7 NADUDP-N-acetylglucosamine 4-epimerase / 0.667
1orr NADCDP-paratose 2-epimerase / 0.666
4yag NAIC alpha-dehydrogenase / 0.665
3qwf NAP17beta-hydroxysteroid dehydrogenase / 0.663
4fn4 NADShort chain dehydrogenase / 0.663
1g6k NADGlucose 1-dehydrogenase 1.1.1.47 0.662
1oaa NAPSepiapterin reductase 1.1.1.153 0.662
2ggs NDPdTDP-4-dehydrorhamnose reductase / 0.661
3ruf NADUDP-N-acetylglucosamine 4-epimerase / 0.661
4dbz NDPPutative ketoacyl reductase 1.3.1 0.661
1eq2 NAPADP-L-glycero-D-manno-heptose-6-epimerase / 0.660
3rud NADUDP-N-acetylglucosamine 4-epimerase / 0.660
4ej0 NAPADP-L-glycero-D-manno-heptose-6-epimerase / 0.660
1fk8 NAD3-alpha-hydroxysteroid dehydrogenase/carbonyl reductase 1.1.1.50 0.659
1zem NADXylitol dehydrogenase / 0.659
3ko8 NADNAD-dependent epimerase/dehydratase / 0.659
4fc7 NAPPeroxisomal 2,4-dienoyl-CoA reductase 1.3.1.34 0.658
3a1n NADNDP-sugar epimerase / 0.657
3pef NAPGlyoxalate/3-oxopropanoate/4-oxobutanoate reductase / 0.657
1bdb NADCis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase / 0.656
3tsc NADUncharacterized protein / 0.656
3sj7 NDP3-oxoacyl-(Acyl-carrier-protein) reductase, putative / 0.655
1ek5 NADUDP-glucose 4-epimerase / 0.654
3ruc NADUDP-N-acetylglucosamine 4-epimerase / 0.654
3ru9 NADUDP-N-acetylglucosamine 4-epimerase / 0.653
4lk3 NADUDP-glucuronic acid decarboxylase 1 4.1.1.35 0.653
4fj2 NAP17beta-hydroxysteroid dehydrogenase / 0.652
5b1y NDP3-oxoacyl-[acyl-carrier-protein] reductase / 0.652
2ekp NAD2-deoxy-D-gluconate 3-dehydrogenase / 0.651
4j7u NAPSepiapterin reductase 1.1.1.153 0.651
3aw9 NADNAD-dependent epimerase/dehydratase / 0.650
3ehe NADUDP-glucose 4-epimerase (GalE-1) / 0.650
3g49 NAPCorticosteroid 11-beta-dehydrogenase isozyme 1 1.1.1.146 0.650
3rue NADUDP-N-acetylglucosamine 4-epimerase / 0.650