sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Modes are compared using Grim.
For more information, please see the following publication:
Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3gy0 | NAP | NAD(P)-dependent oxidoreductase |
| PDB ID | HET | Uniprot Name | EC Number | Binding Mode Similarity |
Align |
|---|---|---|---|---|---|
| 3gy0 | NAP | NAD(P)-dependent oxidoreductase | / | 1.337 | |
| 3iah | NAP | Putative oxoacyl-(Acyl carrier protein) reductase | / | 1.124 | |
| 3p19 | NDP | Putative blue fluorescent protein | / | 0.964 | |
| 4fj0 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.951 | |
| 4j7x | NAP | Sepiapterin reductase | 1.1.1.153 | 0.949 | |
| 3o26 | NDP | Salutaridine reductase | / | 0.945 | |
| 4fj1 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.936 | |
| 5idw | NAP | Short-chain dehydrogenase/reductase SDR | / | 0.932 | |
| 3bhi | NAP | Carbonyl reductase [NADPH] 1 | 1.1.1.184 | 0.924 | |
| 4z3d | NDP | Carbonyl reductase [NADPH] 1 | 1.1.1.184 | 0.921 | |
| 1sny | NAP | LD36273p | / | 0.920 | |
| 4hwk | NAP | Sepiapterin reductase | 1.1.1.153 | 0.913 | |
| 4hp8 | NAP | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.908 | |
| 4j7u | NAP | Sepiapterin reductase | 1.1.1.153 | 0.899 | |
| 4fj2 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.896 | |
| 3r3s | NAD | Putative oxidoreductase | / | 0.891 | |
| 5jyd | NAD | Short chain dehydrogenase | / | 0.891 | |
| 3qwf | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.887 | |
| 1vl8 | NAP | Oxidoreductase, short chain dehydrogenase/reductase family | / | 0.874 | |
| 2d1y | NAD | Oxidoreductase, short-chain dehydrogenase/reductase family | / | 0.871 | |
| 1n5d | NDP | Carbonyl reductase [NADPH] 1 | / | 0.870 | |
| 1edo | NAP | 3-oxoacyl-[acyl-carrier-protein] reductase 1, chloroplastic | 1.1.1.100 | 0.867 | |
| 4pvd | NDP | NADPH-dependent methylglyoxal reductase GRE2 | / | 0.865 | |
| 4b79 | NAD | Probable short-chain dehydrogenase | / | 0.863 | |
| 3f1k | NAP | Uncharacterized oxidoreductase YciK | 1 | 0.858 | |
| 2hrb | NAP | Carbonyl reductase [NADPH] 3 | 1.1.1.184 | 0.855 | |
| 1oaa | NAP | Sepiapterin reductase | 1.1.1.153 | 0.854 | |
| 3l77 | NJP | Short-chain alcohol dehydrogenase | / | 0.849 | |
| 3nug | NAD | Pyridoxal 4-dehydrogenase | 1.1.1.107 | 0.848 | |
| 3tn7 | NJP | Short-chain alcohol dehydrogenase | / | 0.848 | |
| 3h4v | NAP | Pteridine reductase 1 | 1.5.1.33 | 0.847 | |
| 4kwh | NAP | Reductase homolog | / | 0.847 | |
| 3s55 | NAD | Putative short-chain dehydrogenase/reductase | / | 0.843 | |
| 4bmv | NAP | Short-chain dehydrogenase | / | 0.842 | |
| 4zju | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.840 | |
| 1h5q | NAP | NADP-dependent mannitol dehydrogenase | 1.1.1.138 | 0.838 | |
| 3pgx | NAD | Uncharacterized NAD-dependent oxidoreductase MAP_4146 | / | 0.838 | |
| 2jah | NDP | Clavaldehyde dehydrogenase | / | 0.836 | |
| 4fc7 | NAP | Peroxisomal 2,4-dienoyl-CoA reductase | 1.3.1.34 | 0.836 | |
| 3ak4 | NAD | NADH-dependent quinuclidinone reductase | / | 0.831 | |
| 3wds | NAD | NADH-dependent quinuclidinone reductase | / | 0.830 | |
| 1ae1 | NAP | Tropinone reductase 1 | / | 0.829 | |
| 2dkn | NAI | 3-alpha-hydroxysteroid dehydrogenase | / | 0.827 | |
| 2ztm | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.826 | |
| 1xg5 | NAP | Dehydrogenase/reductase SDR family member 11 | / | 0.823 | |
| 3w8d | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.823 | |
| 1rwb | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.819 | |
| 4o0l | NDP | NADPH-dependent 3-quinuclidinone reductase | / | 0.817 | |
| 1cyd | NDP | Carbonyl reductase [NADPH] 2 | 1.1.1.184 | 0.816 | |
| 3rj9 | NAD | Alcohol dehydrogenase | 1.1.1.1 | 0.816 | |
| 3g49 | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.815 | |
| 4nbt | NAD | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.815 | |
| 2q2v | NAD | Beta-D-hydroxybutyrate dehydrogenase | / | 0.813 | |
| 2ztl | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.810 | |
| 3rku | NAP | NADP-dependent 3-hydroxy acid dehydrogenase | / | 0.809 | |
| 4u7w | NDP | MxaA | / | 0.808 | |
| 4clo | NAP | Pteridine reductase | / | 0.807 | |
| 1nfr | NAD | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.806 | |
| 2wyv | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.806 | |
| 5jsf | NAD | 17-beta-hydroxysteroid dehydrogenase 14 | 1.1.1 | 0.804 | |
| 4hxy | NDP | Plm1 | / | 0.803 | |
| 3w8f | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.798 | |
| 1pr9 | NAP | L-xylulose reductase | 1.1.1.10 | 0.796 | |
| 1e3s | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.795 | |
| 4is3 | NAD | 3alpha-hydroxy bile acid-CoA-ester 3-dehydrogenase 2 | 1.17.98.1 | 0.795 | |
| 4dc0 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.794 | |
| 2c29 | NAP | Dihydroflavonol 4-reductase | / | 0.793 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.792 | |
| 1x7g | NAP | Putative ketoacyl reductase | 1.3.1 | 0.791 | |
| 3ndr | NAD | Pyridoxal 4-dehydrogenase | 1.1.1.107 | 0.791 | |
| 3of2 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.791 | |
| 4k6f | NAP | Putative Acetoacetyl-CoA reductase | / | 0.791 | |
| 2ztv | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.790 | |
| 4dc1 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.790 | |
| 5bt9 | NAP | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.789 | |
| 3tox | NAP | Putative oxidoreductase | / | 0.788 | |
| 3w8e | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.788 | |
| 1ipe | NDP | Tropinone reductase 2 | 1.1.1.236 | 0.786 | |
| 1rkx | NAD | CDP-D-glucose-4,6-dehydratase | / | 0.785 | |
| 1geg | NAD | Diacetyl reductase [(S)-acetoin forming] | 1.1.1.304 | 0.784 | |
| 2p5y | NAD | UDP-glucose 4-epimerase | / | 0.784 | |
| 1xse | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.781 | |
| 1g0n | NDP | Tetrahydroxynaphthalene reductase | 1.1.1.252 | 0.779 | |
| 1e6w | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.778 | |
| 2dte | NAI | Glucose 1-dehydrogenase related protein | / | 0.778 | |
| 3ai2 | NDP | NADPH-sorbose reductase | / | 0.778 | |
| 2o23 | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.777 | |
| 2zat | NAP | Dehydrogenase/reductase SDR family member 4 | 1.1.1.184 | 0.777 | |
| 3bmo | NAP | Pteridine reductase | / | 0.777 | |
| 1fdu | NAP | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.775 | |
| 5ig2 | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.775 | |
| 1b16 | NAQ | Alcohol dehydrogenase | 1.1.1.1 | 0.774 | |
| 1w73 | NAP | 2,4-dienoyl-CoA reductase, mitochondrial | 1.3.1.34 | 0.772 | |
| 1w8d | NAP | 2,4-dienoyl-CoA reductase, mitochondrial | 1.3.1.34 | 0.772 | |
| 2b37 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.772 | |
| 4bii | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.772 | |
| 4hbg | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | 1.1.1.100 | 0.772 | |
| 3sx2 | NAD | Uncharacterized protein | / | 0.771 | |
| 1nff | NAD | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.770 | |
| 2b4q | NAP | Rhamnolipids biosynthesis 3-oxoacyl-[acyl-carrier-protein] reductase | 1.1.1.100 | 0.770 | |
| 3ruc | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.770 | |
| 3tsc | NAD | Uncharacterized protein | / | 0.770 | |
| 1gee | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.767 | |
| 2ggs | NDP | dTDP-4-dehydrorhamnose reductase | / | 0.767 | |
| 2yy7 | NAD | L-threonine dehydrogenase | / | 0.766 | |
| 1u7t | TDT | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.764 | |
| 2bd0 | NAP | Sepiapterin reductase | / | 0.764 | |
| 1n7g | NDP | GDP-mannose 4,6 dehydratase 2 | 4.2.1.47 | 0.763 | |
| 1gco | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.762 | |
| 3ruf | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.762 | |
| 4nbu | NAI | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.762 | |
| 4qec | NAP | ElxO | / | 0.762 | |
| 4m87 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.761 | |
| 2nnl | NAP | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.759 | |
| 3d3w | NAP | L-xylulose reductase | 1.1.1.10 | 0.759 | |
| 4yai | NAI | C alpha-dehydrogenase | / | 0.759 | |
| 2yut | NAP | Putative short-chain oxidoreductase | / | 0.758 | |
| 3lu1 | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.758 | |
| 3oew | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.757 | |
| 4dmm | NAP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.757 | |
| 1bdb | NAD | Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase | / | 0.755 | |
| 1n7h | NDP | GDP-mannose 4,6 dehydratase 2 | 4.2.1.47 | 0.755 | |
| 2wsb | NAD | Galactitol dehydrogenase | / | 0.755 | |
| 3qrw | NDP | Putative ketoacyl reductase | 1.3.1 | 0.755 | |
| 2b35 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.753 | |
| 1qyv | NAP | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.752 | |
| 2gdz | NAD | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | 1.1.1.141 | 0.749 | |
| 2y99 | NAD | Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase | 1.3.1.56 | 0.749 | |
| 4bms | NAP | Alclohol dehydrogenase/short-chain dehydrogenase | / | 0.749 | |
| 2ieb | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.748 | |
| 3ko8 | NAD | NAD-dependent epimerase/dehydratase | / | 0.748 | |
| 3oey | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.748 | |
| 3aut | NAI | Glucose 1-dehydrogenase 4 | 1.1.1.47 | 0.747 | |
| 4i5e | NAP | Alclohol dehydrogenase/short-chain dehydrogenase | / | 0.747 | |
| 1x7h | NDP | Putative ketoacyl reductase | 1.3.1 | 0.746 | |
| 4wec | NAD | Short chain dehydrogenase | / | 0.746 | |
| 1xkq | NDP | Uncharacterized protein | / | 0.745 | |
| 2ekp | NAD | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.745 | |
| 3o4r | NAP | Dehydrogenase/reductase SDR family member 4 | 1.1.1.184 | 0.744 | |
| 3rud | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.743 | |
| 5koi | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.743 | |
| 3geg | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.742 | |
| 3sju | NDP | Keto reductase | / | 0.742 | |
| 1rpn | NDP | GDP-mannose 4,6-dehydratase | / | 0.741 | |
| 2aqh | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.741 | |
| 2ie0 | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.741 | |
| 3vdq | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.741 | |
| 4bgi | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.741 | |
| 5d2e | NAP | MlnE | / | 0.741 | |
| 1g1a | NAD | dTDP-glucose 4,6-dehydratase | / | 0.740 | |
| 1mg5 | NAI | Alcohol dehydrogenase | 1.1.1.1 | 0.740 | |
| 2bfo | NDP | Pteridine reductase 1 | 1.5.1.33 | 0.740 | |
| 3ehe | NAD | UDP-glucose 4-epimerase (GalE-1) | / | 0.740 | |
| 3rua | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.740 | |
| 5jy1 | NAD | Putative short-chain dehydrogenase/reductase | / | 0.740 | |
| 3ruh | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.739 | |
| 5jla | NAD | Putative short-chain dehydrogenase/reductase | / | 0.739 | |
| 3mje | NDP | AmphB | / | 0.736 | |
| 4oxy | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.735 | |
| 4qed | NAP | ElxO | / | 0.735 | |
| 1eny | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.733 | |
| 3uic | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.733 | |
| 3uce | NDP | Dehydrogenase | / | 0.732 | |
| 1e3w | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.731 | |
| 1iy8 | NAD | Levodione reductase | / | 0.731 | |
| 2c59 | NAD | GDP-mannose 3,5-epimerase | 5.1.3.18 | 0.731 | |
| 2idz | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.731 | |
| 4gh5 | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.730 | |
| 4yag | NAI | C alpha-dehydrogenase | / | 0.730 | |
| 4fn4 | NAD | Short chain dehydrogenase | / | 0.725 | |
| 2aq8 | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.724 | |
| 2ydx | NAP | Methionine adenosyltransferase 2 subunit beta | / | 0.724 | |
| 4rf2 | NAP | NADPH dependent R-specific alcohol dehydrogenase | / | 0.724 | |
| 1kvr | NAD | UDP-glucose 4-epimerase | 5.1.3.2 | 0.723 | |
| 2aqi | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.723 | |
| 2q1t | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.723 | |
| 2rbe | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.722 | |
| 3ru9 | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.722 | |
| 4gll | NAD | UDP-glucuronic acid decarboxylase 1 | 4.1.1.35 | 0.722 | |
| 5b1y | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.721 | |
| 2c54 | NAD | GDP-mannose 3,5-epimerase | 5.1.3.18 | 0.720 | |
| 3ijr | NAD | Oxidoreductase, short chain dehydrogenase/reductase family | / | 0.720 | |
| 2q2q | NAD | Beta-D-hydroxybutyrate dehydrogenase | / | 0.719 | |
| 1bxk | NAD | dTDP-glucose 4,6-dehydratase 2 | / | 0.718 | |
| 1orr | NAD | CDP-paratose 2-epimerase | / | 0.718 | |
| 5cpb | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.718 | |
| 1sby | NAD | Alcohol dehydrogenase | 1.1.1.1 | 0.717 | |
| 3a28 | NAD | L-2,3-butanediol dehydrogenase | 1.1.1.76 | 0.717 | |
| 4dre | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.717 | |
| 3icp | NAD | NAD-dependent epimerase/dehydratase | / | 0.715 | |
| 3rj5 | NAD | Alcohol dehydrogenase | 1.1.1.1 | 0.715 | |
| 3wmx | NAD | NAD dependent epimerase/dehydratase | / | 0.715 | |
| 4trn | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.714 | |
| 2nv6 | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.712 | |
| 2q1s | NAI | Putative nucleotide sugar epimerase/ dehydratase | / | 0.712 | |
| 1g6k | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.711 | |
| 1b2l | NDC | Alcohol dehydrogenase | 1.1.1.1 | 0.710 | |
| 2ztu | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.710 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.710 | |
| 4imp | NDP | Polyketide synthase extender modules 3-4 | / | 0.708 | |
| 2q1u | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.706 | |
| 3rue | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.706 | |
| 5lc1 | NAD | L-threonine 3-dehydrogenase | / | 0.705 | |
| 5js6 | NAD | 17-beta-hydroxysteroid dehydrogenase 14 | 1.1.1 | 0.704 | |
| 1vrw | NAI | Enoyl-ACP reductase | / | 0.702 | |
| 3o03 | NAP | Dehydrogenase with different specificities (Related to short-chain alcohol dehydrogenase) | / | 0.702 | |
| 2yw9 | NAP | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.700 | |
| 2nq8 | ZID | Enoyl-ACP reductase | / | 0.699 | |
| 4e5y | NDP | GDP-L-fucose synthase | 1.1.1.271 | 0.699 | |
| 1eq2 | NAP | ADP-L-glycero-D-manno-heptose-6-epimerase | / | 0.698 | |
| 2pzj | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.697 | |
| 3a4v | NAD | NDP-sugar epimerase | / | 0.697 | |
| 3ai3 | NDP | NADPH-sorbose reductase | / | 0.697 | |
| 1p44 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.695 | |
| 1w4z | NAP | Putative ketoacyl reductase | 1.3.1 | 0.695 | |
| 4dqu | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.695 | |
| 4iqg | NAP | Short-chain dehydrogenase/reductase SDR | / | 0.694 | |
| 1fk8 | NAD | 3-alpha-hydroxysteroid dehydrogenase/carbonyl reductase | 1.1.1.50 | 0.693 | |
| 2z1m | NDP | GDP-mannose 4,6-dehydratase | / | 0.693 | |
| 3a9w | NAD | NDP-sugar epimerase | / | 0.693 | |
| 2ag5 | NAD | 3-hydroxybutyrate dehydrogenase type 2 | / | 0.691 | |
| 2gn8 | NAP | UDP-N-acetylglucosamine 4,6-dehydratase (inverting) | 4.2.1.115 | 0.689 | |
| 3aw9 | NAD | NAD-dependent epimerase/dehydratase | / | 0.689 | |
| 1u7t | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.688 | |
| 4bqp | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.687 | |
| 2bgm | NAJ | Secoisolariciresinol dehydrogenase | 1.1.1.331 | 0.685 | |
| 1n2s | NAI | dTDP-4-dehydrorhamnose reductase | 1.1.1.133 | 0.683 | |
| 1ahh | NAD | 7-alpha-hydroxysteroid dehydrogenase | 1.1.1.159 | 0.682 | |
| 3ru7 | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.682 | |
| 4b8z | NAP | GDP-L-fucose synthase | 1.1.1.271 | 0.682 | |
| 2h9i | EAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.681 | |
| 4o1m | NAD | Enoyl-acyl carrier reductase | / | 0.680 | |
| 3ajr | NAD | NDP-sugar epimerase | / | 0.678 | |
| 1b15 | NAE | Alcohol dehydrogenase | 1.1.1.1 | 0.677 | |
| 1t2a | NDP | GDP-mannose 4,6 dehydratase | 4.2.1.47 | 0.677 | |
| 3sj7 | NDP | 3-oxoacyl-(Acyl-carrier-protein) reductase, putative | / | 0.677 | |
| 3sxp | NAD | ADP-L-glycero-D-mannoheptose-6-epimerase | / | 0.677 | |
| 4egb | NAD | dTDP-glucose 4,6-dehydratase | / | 0.676 | |
| 4lis | NAD | UDP-glucose 4-epimerase (Eurofung) | / | 0.676 | |
| 2b36 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.675 | |
| 4dti | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.675 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.674 | |
| 4nbw | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.673 | |
| 2aqk | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.671 | |
| 1wnt | NAP | L-xylulose reductase | 1.1.1.10 | 0.669 | |
| 4eso | NAP | Putative oxidoreductase | / | 0.669 | |
| 4tqg | NDP | Putative dTDP-d-glucose 4 6-dehydratase | / | 0.668 | |
| 4yr9 | NAD | L-threonine 3-dehydrogenase, mitochondrial | 1.1.1.103 | 0.667 | |
| 3pdu | NAP | Glyoxalate/3-oxopropanoate/4-oxobutanoate reductase | / | 0.666 | |
| 1wvg | APR | CDP-glucose 4,6-dehydratase | 4.2.1.45 | 0.665 | |
| 2b69 | NAD | UDP-glucuronic acid decarboxylase 1 | 4.1.1.35 | 0.664 | |
| 4cql | NAD | Estradiol 17-beta-dehydrogenase 8 | 1.1.1.62 | 0.664 | |
| 4y1b | NAP | AntE | / | 0.663 | |
| 2ntv | P1H | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.661 | |
| 3u4c | NDP | NADPH-dependent reductase BacG | / | 0.660 | |
| 4b8w | NAP | GDP-L-fucose synthase | 1.1.1.271 | 0.658 | |
| 4bv9 | NDP | Ketimine reductase mu-crystallin | 1.5.1.25 | 0.654 | |
| 4nd3 | NAD | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.654 | |
| 1e5q | NDP | Saccharopine dehydrogenase [NADP(+), L-glutamate-forming] | 1.5.1.10 | 0.653 | |
| 4bkq | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.653 | |
| 5hws | NAP | 2-dehydropantoate 2-reductase | / | 0.653 | |
| 1t2d | NAD | L-lactate dehydrogenase | 1.1.1.27 | 0.652 | |
| 2pk3 | A2R | GDP-6-deoxy-D-mannose reductase | / | 0.651 | |
| 4fda | NAP | 3-oxoacyl-[acyl-carrier-protein] reductase | 1.1.1.100 | 0.651 | |
| 1v35 | NAI | Enoyl-ACP reductase | / | 0.650 | |
| 3a1n | NAD | NDP-sugar epimerase | / | 0.650 |